Year |
Citation |
Score |
2023 |
Zhang J, Xiang Q, Wu M, Lao YZ, Xian YF, Xu HX, Lin ZX. Autophagy Regulators in Cancer. International Journal of Molecular Sciences. 24. PMID 37446120 DOI: 10.3390/ijms241310944 |
0.33 |
|
2022 |
Tan JQ, Li Z, Chen G, Wu M, Feng JL, Kong SY, Shi XQ, Zhang HM, Lao YZ, Zhou H, Zhang L, Xu HX. The natural compound from Garcinia bracteata mainly induces GSDME-mediated pyroptosis in esophageal cancer cells. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 102: 154142. PMID 35623158 DOI: 10.1016/j.phymed.2022.154142 |
0.329 |
|
2022 |
Zheng Z, Tan J, Zhang J, Wu M, Chen G, Li Z, Shi X, Fu W, Zhou H, Lao Y, Zhang L, Xu H. The natural compound neobractatin inhibits cell proliferation mainly by regulating the RNA binding protein CELF6. Food & Function. PMID 35088780 DOI: 10.1039/d1fo03542h |
0.321 |
|
2020 |
Han L, Xu D, Xi Z, Wu M, Nik Nabil WN, Zhang J, Sui H, Fu W, Zhou H, Lao Y, Xu G, Guo C, Xu H. The Natural Compound Oblongifolin C Exhibits Anticancer Activity by Inhibiting HSPA8 and Cathepsin B . Frontiers in Pharmacology. 11: 564833. PMID 33390942 DOI: 10.3389/fphar.2020.564833 |
0.339 |
|
2020 |
Wu M, Lu G, Lao YZ, Zhang H, Zheng D, Zheng ZQ, Yi J, Xiang Q, Wang LM, Tan HS, Zhou H, Shen HM, Xu HX. Garciesculenxanthone B induces PINK1-Parkin-mediated mitophagy and prevents ischemia-reperfusion brain injury in mice. Acta Pharmacologica Sinica. PMID 32759963 DOI: 10.1038/S41401-020-0480-9 |
0.371 |
|
2020 |
Xiang Q, Wu M, Zhang L, Fu W, Yang J, Zhang B, Zheng Z, Zhang H, Lao Y, Xu H. Gerontoxanthone I and Macluraxanthone Induce Mitophagy and Attenuate Ischemia/Reperfusion Injury. Frontiers in Pharmacology. 11: 452. PMID 32351391 DOI: 10.3389/Fphar.2020.00452 |
0.366 |
|
2020 |
Ye YS, Wu M, Jiang NN, Lao YZ, Fu WW, Liu X, Yang XW, Zhang J, Xu HX, Xu G. Dearomatized Isoprenylated Acylphloroglucinol Derivatives with Potential Antitumor Activities from Hypericum henryi. Natural Products and Bioprospecting. PMID 32016770 DOI: 10.1007/S13659-019-00229-W |
0.468 |
|
2019 |
Yuan M, Xu LF, Zhang J, Kong SY, Wu M, Lao YZ, Zhou H, Zhang L, Xu H. SRC and MEK Co-inhibition Synergistically Enhances the Anti-tumor Effect in Both Non-small-cell Lung Cancer (NSCLC) and Erlotinib-Resistant NSCLC. Frontiers in Oncology. 9: 586. PMID 31428570 DOI: 10.3389/Fonc.2019.00586 |
0.393 |
|
2019 |
Zheng Z, Wu M, Zhang J, Fu W, Xu N, Lao Y, Lin L, Xu H. The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45α. Frontiers in Oncology. 9: 654. PMID 31380287 DOI: 10.3389/Fonc.2019.00654 |
0.674 |
|
2019 |
Wang J, Wu M, Zheng D, Zhang H, Lv Y, Zhang L, Tan HS, Zhou H, Lao YZ, Xu HX. Garcinol inhibits esophageal cancer metastasis by suppressing the p300 and TGF-β1 signaling pathways. Acta Pharmacologica Sinica. PMID 31371781 DOI: 10.1038/S41401-019-0271-3 |
0.412 |
|
2019 |
Zhang J, Zheng Z, Wu M, Zhang L, Wang J, Fu W, Xu N, Zhao Z, Lao Y, Xu H. The natural compound neobractatin inhibits tumor metastasis by upregulating the RNA-binding-protein MBNL2. Cell Death & Disease. 10: 554. PMID 31320607 DOI: 10.1038/S41419-019-1789-5 |
0.662 |
|
2018 |
Wu M, Lao YZ, Tan HS, Lu G, Ren Y, Zheng ZQ, Yi J, Fu WW, Shen HM, Xu HX. Oblongifolin C suppresses lysosomal function independently of TFEB nuclear translocation. Acta Pharmacologica Sinica. PMID 30333555 DOI: 10.1038/S41401-018-0167-7 |
0.431 |
|
2018 |
Jiang SL, Guan YD, Chen XS, Ge P, Wang XL, Lao YZ, Xiao SS, Zhang Y, Yang JM, Xu XJ, Cao DS, Cheng Y. Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway. Acta Pharmacologica Sinica. PMID 30315250 DOI: 10.1038/S41401-018-0165-9 |
0.481 |
|
2018 |
Li Y, Xi Z, Chen X, Cai S, Liang C, Wang Z, Li Y, Tan H, Lao Y, Xu H. Natural compound Oblongifolin C confers gemcitabine resistance in pancreatic cancer by downregulating Src/MAPK/ERK pathways. Cell Death & Disease. 9: 538. PMID 29749405 DOI: 10.1038/S41419-018-0574-1 |
0.41 |
|
2018 |
Xu L, Meng X, Xu N, Fu W, Tan H, Zhang L, Zhou Q, Qian J, Tu S, Li X, Lao Y, Xu H. Gambogenic acid inhibits fibroblast growth factor receptor signaling pathway in erlotinib-resistant non-small-cell lung cancer and suppresses patient-derived xenograft growth. Cell Death & Disease. 9: 262. PMID 29449529 DOI: 10.1038/S41419-018-0314-6 |
0.638 |
|
2018 |
Duan Y, Zhang J, Lao Y, Tan H, Ye Y, Yang X, Xu H, Xu G. Spirocyclic polycyclic polyprenylated acylphloroglucinols from the ethyl acetate fraction of Hypericum henryi Tetrahedron Letters. 59: 4067-4072. DOI: 10.1016/J.Tetlet.2018.09.071 |
0.337 |
|
2017 |
Hu K, Yin F, Yu M, Sun C, Li J, Liang Y, Li W, Xie M, Lao Y, Liang W, Li ZG. In-Tether Chiral Center Induced Helical Peptide Modulators Target p53-MDM2/MDMX and Inhibit Tumor Growth in Stem-Like Cancer Cell. Theranostics. 7: 4566-4576. PMID 29158845 DOI: 10.7150/Thno.19840 |
0.408 |
|
2017 |
Liu L, He J, Wei X, Wan G, Lao Y, Xu W, Li Z, Hu H, Hu Z, Luo X, Wu J, Xie W, Zhang Y, Xu N. MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability. Oncogene. PMID 28628113 DOI: 10.1038/Onc.2017.193 |
0.339 |
|
2017 |
Wang X, Xu L, Lao Y, Zhang H, Xu H. Natural products targeting EGFR signaling pathways as potential anticancer drugs. Current Protein & Peptide Science. PMID 28059040 DOI: 10.2174/1389203718666170106104211 |
0.334 |
|
2017 |
Xu H, Ding Z, Xu D, Lao Y. Interactions between traditional chinese medicine and anticancer drugs in chemotherapy World Journal of Traditional Chinese Medicine. 3: 38. DOI: 10.4103/Wjtcm.Wjtcm_6_17 |
0.365 |
|
2016 |
Li H, Meng XX, Zhang L, Zhang BJ, Liu XY, Fu WW, Tan HS, Lao YZ, Xu HX. Oblongifolin C and guttiferone K extracted from Garcinia yunnanensis fruit synergistically induce apoptosis in human colorectal cancer cells in vitro. Acta Pharmacologica Sinica. PMID 27840412 DOI: 10.1038/Aps.2016.101 |
0.475 |
|
2016 |
Zhang H, Dan Z, Ding ZJ, Lao YZ, Tan HS, Xu HX. UPLC-PDA-QTOFMS-guided isolation of prenylated xanthones and benzoylphloroglucinols from the leaves of Garcinia oblongifolia and their migration-inhibitory activity. Scientific Reports. 6: 35789. PMID 27767059 DOI: 10.1038/Srep35789 |
0.371 |
|
2016 |
Zhang L, Kong SY, Zheng ZQ, Meng XX, Feng JL, Tan HS, Lao YZ, Xiao LB, Xu HX. Nujiangexathone A, a Novel Compound Derived from Garcinia nujiangensis, Induces Caspase-Dependent Apoptosis in Cervical Cancer through the ROS/JNK Pathway. Molecules (Basel, Switzerland). 21. PMID 27754347 DOI: 10.3390/Molecules21101360 |
0.48 |
|
2016 |
Zhao H, Liu QS, Geng H, Tian Y, Cheng M, Jiang YH, Xie MS, Niu XG, Jiang F, Zhang YO, Lao YZ, Wu YD, Xu NH, Li ZG. Crosslinked Aspartic Acids as Helix-Nucleating Templates. Angewandte Chemie (International Ed. in English). PMID 27572954 DOI: 10.1002/Anie.201606833 |
0.566 |
|
2016 |
Liu Q, Zhao H, Jiang Y, Wu M, Tian Y, Wang D, Lao Y, Xu N, Li Z. Development of a lytic peptide derived from BH3-only proteins. Cell Death Discovery. 2: 16008. PMID 27551502 DOI: 10.1038/Cddiscovery.2016.8 |
0.331 |
|
2016 |
Zhang L, Feng J, Kong S, Wu M, Xi Z, Zhang B, Fu W, Lao Y, Tan H, Xu H. Nujiangexathone A, a novel compound from Garcinia nujiangensis, suppresses cervical cancer growth by targeting hnRNPK. Cancer Letters. PMID 27424288 DOI: 10.1016/J.Canlet.2016.07.005 |
0.483 |
|
2016 |
Wang L, Wu R, Fu W, Lao Y, Zheng C, Tan H, Xu H. Synthesis and biological evaluation of Oblongifolin C derivatives as c-Met inhibitors. Bioorganic & Medicinal Chemistry. PMID 27396929 DOI: 10.1016/J.Bmc.2016.06.054 |
0.358 |
|
2016 |
Cheng M, Liu L, Lao Y, Liao W, Liao M, Luo X, Wu J, Xie W, Zhang Y, Xu N. MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis. Oncotarget. PMID 27281615 DOI: 10.18632/Oncotarget.9786 |
0.623 |
|
2016 |
Xi Z, Yao M, Li Y, Xie C, Holst J, Liu T, Cai S, Lao Y, Tan H, Xu HX, Dong Q. Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation. Cell Death & Disease. 7: e2252. PMID 27253416 DOI: 10.1038/Cddis.2016.123 |
0.397 |
|
2016 |
Lao Y, Xu N. Autophagy in Cancer Chemoprevention: Identification of Novel Autophagy Modulators with Anticancer Potential. Methods in Molecular Biology (Clifton, N.J.). 1379: 151-63. PMID 26608298 DOI: 10.1007/978-1-4939-3191-0_14 |
0.671 |
|
2015 |
Ding Z, Lao Y, Zhang H, Fu W, Zhu L, Tan H, Xu H. Griffipavixanthone, a dimeric xanthone extracted from edible plants, inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer. Oncotarget. PMID 26646323 DOI: 10.18632/Oncotarget.6484 |
0.452 |
|
2015 |
Wu M, Lao Y, Xu N, Wang X, Tan H, Fu W, Lin Z, Xu H. Guttiferone K induces autophagy and sensitizes cancer cells to nutrient stress-induced cell death. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 22: 902-10. PMID 26321739 DOI: 10.1016/J.Phymed.2015.06.008 |
0.662 |
|
2015 |
Xia Z, Zhang H, Xu D, Lao Y, Fu W, Tan H, Cao P, Yang L, Xu H. Xanthones from the Leaves of Garcinia cowa Induce Cell Cycle Arrest, Apoptosis, and Autophagy in Cancer Cells. Molecules (Basel, Switzerland). 20: 11387-99. PMID 26102071 DOI: 10.3390/Molecules200611387 |
0.461 |
|
2015 |
Xu L, Lao Y, Zhao Y, Qin J, Fu W, Zhang Y, Xu H. Screening Active Compounds from Garcinia Species Native to China Reveals Novel Compounds Targeting the STAT/JAK Signaling Pathway. Biomed Research International. 2015: 910453. PMID 26090459 DOI: 10.1155/2015/910453 |
0.427 |
|
2015 |
Wang X, Lao Y, Xu N, Xi Z, Wu M, Wang H, Li X, Tan H, Sun M, Xu H. Oblongifolin C inhibits metastasis by up-regulating keratin 18 and tubulins. Scientific Reports. 5: 10293. PMID 25973684 DOI: 10.1038/Srep10293 |
0.665 |
|
2015 |
Li X, Lao Y, Zhang H, Wang X, Tan H, Lin Z, Xu H. The natural compound Guttiferone F sensitizes prostate cancer to starvation induced apoptosis via calcium and JNK elevation. Bmc Cancer. 15: 254. PMID 25885018 DOI: 10.1186/S12885-015-1292-Z |
0.37 |
|
2015 |
Xu W, Cheng M, Lao Y, Wang X, Wu J, Zhou L, Zhang Y, Xu H, Xu N. DNA damage and ER stress contribute to oblongifolin C-induced cell killing in Bax/Bak-deficient cells. Biochemical and Biophysical Research Communications. 457: 300-6. PMID 25576357 DOI: 10.1016/J.Bbrc.2014.12.104 |
0.719 |
|
2015 |
Xu D, Lao Y, Xu N, Hu H, Fu W, Tan H, Gu Y, Song Z, Cao P, Xu H. Identification and characterization of anticancer compounds targeting apoptosis and autophagy from Chinese native Garcinia species. Planta Medica. 81: 79-89. PMID 25478784 DOI: 10.1055/S-0034-1383356 |
0.682 |
|
2015 |
Fu W, Wu M, Zhu L, Lao Y, Wang L, Tan H, Yuan Q, Xu H. Prenylated benzoylphloroglucinols and biphenyl derivatives from the leaves of Garcinia multiflora Champ Rsc Advances. 5: 78259-78267. DOI: 10.1039/C5Ra09213B |
0.433 |
|
2014 |
Xiao K, Wang Y, Chang Z, Lao Y, Chang DC. p32, a novel binding partner of Mcl-1, positively regulates mitochondrial Ca(2+) uptake and apoptosis. Biochemical and Biophysical Research Communications. 451: 322-8. PMID 25091479 DOI: 10.1016/J.Bbrc.2014.07.122 |
0.638 |
|
2014 |
Zhang H, Zhang DD, Lao YZ, Fu WW, Liang S, Yuan QH, Yang L, Xu HX. Cytotoxic and anti-inflammatory prenylated benzoylphloroglucinols and xanthones from the twigs of Garcinia esculenta. Journal of Natural Products. 77: 1700-7. PMID 24960143 DOI: 10.1021/Np5003498 |
0.366 |
|
2014 |
Lao Y, Wang X, Xu N, Zhang H, Xu H. Application of proteomics to determine the mechanism of action of traditional Chinese medicine remedies. Journal of Ethnopharmacology. 155: 1-8. PMID 24862488 DOI: 10.1016/J.Jep.2014.05.022 |
0.604 |
|
2014 |
Lao Y, Wan G, Liu Z, Wang X, Ruan P, Xu W, Xu D, Xie W, Zhang Y, Xu H, Xu N. The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation. Autophagy. 10: 736-49. PMID 24642486 DOI: 10.4161/Auto.28034 |
0.696 |
|
2014 |
Wan G, Xie W, Liu Z, Xu W, Lao Y, Huang N, Cui K, Liao M, He J, Jiang Y, Yang BB, Xu H, Xu N, Zhang Y. Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway. Autophagy. 10: 70-9. PMID 24262949 DOI: 10.4161/Auto.26534 |
0.629 |
|
2014 |
Xiao SJ, Lao YZ, Chen F, Xu HX, Ding LS, Zhou Y. Two new lignans from Gymnotheca chinensis Decne Phytochemistry Letters. 8: 38-40. DOI: 10.1016/J.Phytol.2014.01.007 |
0.343 |
|
2012 |
Xia ZX, Zhang DD, Liang S, Lao YZ, Zhang H, Tan HS, Chen SL, Wang XH, Xu HX. Bioassay-guided isolation of prenylated xanthones and polycyclic acylphloroglucinols from the leaves of Garcinia nujiangensis. Journal of Natural Products. 75: 1459-64. PMID 22871217 DOI: 10.1021/Np3003639 |
0.369 |
|
2012 |
Xu N, Lao Y, Zhang Y, Gillespie DA. Akt: a double-edged sword in cell proliferation and genome stability. Journal of Oncology. 2012: 951724. PMID 22481935 DOI: 10.1155/2012/951724 |
0.636 |
|
2012 |
Xu N, Libertini S, Black EJ, Lao Y, Hegarat N, Walker M, Gillespie DA. Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage. Oncogene. 31: 1086-94. PMID 21765472 DOI: 10.1038/Onc.2011.310 |
0.33 |
|
2008 |
Lao Y, Chang DC. Mobilization of Ca2+ from endoplasmic reticulum to mitochondria plays a positive role in the early stage of UV- or TNFalpha-induced apoptosis. Biochemical and Biophysical Research Communications. 373: 42-7. PMID 18544340 DOI: 10.1016/J.Bbrc.2008.05.172 |
0.539 |
|
2008 |
Liu YW, Li CY, Luo JL, Li WM, Fu HJ, Lao YZ, Liu LJ, Pang YP, Chang DC, Li ZW, Peoples RW, Ai YX, Han YF. Bis(7)-tacrine prevents glutamate-induced excitotoxicity more potently than memantine by selectively inhibiting NMDA receptors. Biochemical and Biophysical Research Communications. 369: 1007-11. PMID 18328812 DOI: 10.1016/J.Bbrc.2008.02.133 |
0.437 |
|
2007 |
Lao Y, Chang DC. Study of the functional role of Bcl-2 family proteins in regulating Ca(2+) signals in apoptotic cells. Biochemical Society Transactions. 35: 1038-9. PMID 17956272 DOI: 10.1042/BST0351038 |
0.457 |
|
2007 |
Fu H, Li W, Liu Y, Lao Y, Liu W, Chen C, Yu H, Lee NT, Chang DC, Li P, Pang Y, Tsim KW, Li M, Han Y. Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons. Journal of Proteome Research. 6: 2435-46. PMID 17530875 DOI: 10.1021/Pr060615G |
0.541 |
|
2006 |
Fu H, Li W, Lao Y, Luo J, Lee NT, Kan KK, Tsang HW, Tsim KW, Pang Y, Li Z, Chang DC, Li M, Han Y. Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels. Journal of Neurochemistry. 98: 1400-10. PMID 16771827 DOI: 10.1111/J.1471-4159.2006.03960.X |
0.519 |
|
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