| Year |
Citation |
Score |
| 2015 |
Ganguly A, Cabral F, Yang H, Patel KD. Peloruside A is a microtubule-stabilizing agent with exceptional anti-migratory properties in human endothelial cells. Oncoscience. 2: 585-95. PMID 26244166 DOI: 10.18632/oncoscience.169 |
0.653 |
|
| 2014 |
Kanakkanthara A, Eras J, Northcote PT, Cabral F, Miller JH. Resistance to peloruside A and laulimalide: functional significance of acquired βI-tubulin mutations at sites important for drug-tubulin binding. Current Cancer Drug Targets. 14: 79-90. PMID 24245693 DOI: 10.2174/1568009613666131113101151 |
0.493 |
|
| 2013 |
Yin S, Zeng C, Hari M, Cabral F. Paclitaxel resistance by random mutagenesis of α-tubulin. Cytoskeleton (Hoboken, N.J.). 70: 849-62. PMID 24155014 DOI: 10.1002/Cm.21154 |
0.794 |
|
| 2013 |
Ganguly A, Yang H, Zhang H, Cabral F, Patel KD. Microtubule dynamics control tail retraction in migrating vascular endothelial cells. Molecular Cancer Therapeutics. 12: 2837-46. PMID 24107446 DOI: 10.1158/1535-7163.Mct-13-0401 |
0.689 |
|
| 2013 |
Ganguly A, Yang H, Cabral F. Detection and quantification of microtubule detachment from centrosomes and spindle poles. Methods in Cell Biology. 115: 49-62. PMID 23973065 DOI: 10.1016/B978-0-12-407757-7.00004-9 |
0.729 |
|
| 2012 |
Ganguly A, Yang H, Sharma R, Patel KD, Cabral F. The role of microtubules and their dynamics in cell migration. The Journal of Biological Chemistry. 287: 43359-69. PMID 23135278 DOI: 10.1074/Jbc.M112.423905 |
0.713 |
|
| 2012 |
Yin S, Zeng C, Hari M, Cabral F. Random mutagenesis of β-tubulin defines a set of dispersed mutations that confer paclitaxel resistance. Pharmaceutical Research. 29: 2994-3006. PMID 22669706 DOI: 10.1007/S11095-012-0794-5 |
0.788 |
|
| 2012 |
Ganguly A, Bhattacharya R, Cabral F. Control of MCAK degradation and removal from centromeres. Cytoskeleton (Hoboken, N.J.). 69: 303-11. PMID 22422706 DOI: 10.1002/Cm.21026 |
0.498 |
|
| 2011 |
Ganguly A, Yang H, Pedroza M, Bhattacharya R, Cabral F. Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance. The Journal of Biological Chemistry. 286: 36378-84. PMID 21903575 DOI: 10.1074/Jbc.M111.296483 |
0.747 |
|
| 2011 |
Ganguly A, Cabral F. The arresting action of microtubules in cell motility. Cell Cycle (Georgetown, Tex.). 10: 2614-5. PMID 21778828 DOI: 10.4161/Cc.10.16.16593 |
0.557 |
|
| 2011 |
Ganguly A, Cabral F. New insights into mechanisms of resistance to microtubule inhibitors. Biochimica Et Biophysica Acta. 1816: 164-71. PMID 21741453 DOI: 10.1016/J.Bbcan.2011.06.001 |
0.546 |
|
| 2011 |
Ganguly A, Yang H, Cabral F. Class III β-tubulin counteracts the ability of paclitaxel to inhibit cell migration. Oncotarget. 2: 368-77. PMID 21576762 DOI: 10.18632/Oncotarget.250 |
0.692 |
|
| 2011 |
Ganguly A, Yang H, Cabral F. Overexpression of mitotic centromere-associated Kinesin stimulates microtubule detachment and confers resistance to paclitaxel. Molecular Cancer Therapeutics. 10: 929-37. PMID 21471284 DOI: 10.1158/1535-7163.Mct-10-1109 |
0.75 |
|
| 2011 |
Yang H, Ganguly A, Yin S, Cabral F. Megakaryocyte lineage-specific class VI β-tubulin suppresses microtubule dynamics, fragments microtubules, and blocks cell division. Cytoskeleton (Hoboken, N.J.). 68: 175-87. PMID 21309084 DOI: 10.1002/Cm.20503 |
0.771 |
|
| 2011 |
Bhattacharya R, Yang H, Cabral F. Class V β-tubulin alters dynamic instability and stimulates microtubule detachment from centrosomes. Molecular Biology of the Cell. 22: 1025-34. PMID 21289088 DOI: 10.1091/Mbc.E10-10-0822 |
0.705 |
|
| 2010 |
Ganguly A, Yang H, Cabral F. Paclitaxel-dependent cell lines reveal a novel drug activity. Molecular Cancer Therapeutics. 9: 2914-23. PMID 20978163 DOI: 10.1158/1535-7163.Mct-10-0552 |
0.731 |
|
| 2010 |
Yang H, Ganguly A, Cabral F. Inhibition of cell migration and cell division correlates with distinct effects of microtubule inhibiting drugs. The Journal of Biological Chemistry. 285: 32242-50. PMID 20696757 DOI: 10.1074/Jbc.M110.160820 |
0.705 |
|
| 2010 |
Yin S, Bhattacharya R, Cabral F. Human mutations that confer paclitaxel resistance. Molecular Cancer Therapeutics. 9: 327-35. PMID 20103599 DOI: 10.1158/1535-7163.Mct-09-0674 |
0.805 |
|
| 2010 |
Ganguly A, Yang H, Cabral F. Abstract LB-53: Paclitaxel inhibits microtubule detachment from centrosomes Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-53 |
0.694 |
|
| 2010 |
Bhattacharya R, Yang H, Cabral F. Abstract 2489: Dramatically increased microtubule shortening resulting from overexpression of β5-tubulin is reversed by paclitaxel Cancer Research. 70: 2489-2489. DOI: 10.1158/1538-7445.Am10-2489 |
0.703 |
|
| 2009 |
Yang H, Cabral F, Bhattacharya R. Tubulin isotype specificity and identification of the epitope for antibody Tub 2.1. Protein Engineering, Design & Selection : Peds. 22: 625-9. PMID 19625384 DOI: 10.1093/Protein/Gzp046 |
0.576 |
|
| 2009 |
Bhattacharya R, Cabral F. Molecular Basis for Class V β-Tubulin Effects on Microtubule Assembly and Paclitaxel Resistance Journal of Biological Chemistry. 284: 13023-13032. PMID 19282281 DOI: 10.1074/Jbc.M900167200 |
0.535 |
|
| 2008 |
Ganguly A, Bhattacharya R, Cabral F. Cell cycle dependent degradation of MCAK: evidence against a role in anaphase chromosome movement. Cell Cycle (Georgetown, Tex.). 7: 3187-93. PMID 18843200 DOI: 10.4161/Cc.7.20.6814 |
0.346 |
|
| 2008 |
Bhattacharya R, Frankfurter A, Cabral F. A minor β‐tubulin essential for mammalian cell proliferation Cytoskeleton. 65: 708-720. PMID 18553364 DOI: 10.1002/Cm.20292 |
0.495 |
|
| 2007 |
Yin S, Cabral F, Veeraraghavan S. Amino acid substitutions at proline 220 of beta-tubulin confer resistance to paclitaxel and colcemid. Molecular Cancer Therapeutics. 6: 2798-806. PMID 17938271 DOI: 10.1158/1535-7163.Mct-06-0791 |
0.803 |
|
| 2007 |
Yang H, Cabral F. Heightened sensitivity to paclitaxel in Class IVa beta-tubulin-transfected cells is lost as expression increases. The Journal of Biological Chemistry. 282: 27058-66. PMID 17627938 DOI: 10.1074/Jbc.M704101200 |
0.724 |
|
| 2006 |
Wang Y, Tian G, Cowan NJ, Cabral F. Mutations affecting beta-tubulin folding and degradation. The Journal of Biological Chemistry. 281: 13628-35. PMID 16554299 DOI: 10.1074/Jbc.M513730200 |
0.475 |
|
| 2006 |
Wang Y, Yin S, Blade K, Cooper G, Menick DR, Cabral F. Mutations at leucine 215 of beta-tubulin affect paclitaxel sensitivity by two distinct mechanisms. Biochemistry. 45: 185-94. PMID 16388594 DOI: 10.1021/Bi051207D |
0.801 |
|
| 2005 |
Wang Y, Cabral F. Paclitaxel resistance in cells with reduced β-tubulin Biochimica Et Biophysica Acta. 1744: 245-255. PMID 15950754 DOI: 10.1016/J.Bbamcr.2004.12.003 |
0.603 |
|
| 2005 |
Kamath K, Wilson L, Cabral F, Jordan MA. BetaIII-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability. The Journal of Biological Chemistry. 280: 12902-7. PMID 15695826 DOI: 10.1074/Jbc.M414477200 |
0.564 |
|
| 2004 |
Wang Y, Veeraraghavan S, Cabral F. Intra-allelic suppression of a mutation that stabilizes microtubules and confers resistance to colcemid. Biochemistry. 43: 8965-8973. PMID 15248754 DOI: 10.1021/Bi049637B |
0.624 |
|
| 2004 |
Bhattacharya R, Cabral F. A Ubiquitous β-tubulin Disrupts Microtubule Assembly and Inhibits Cell Proliferation Molecular Biology of the Cell. 15: 3123-3131. PMID 15121885 DOI: 10.1091/Mbc.E04-01-0060 |
0.436 |
|
| 2003 |
Cabral F, Abraham I, Gottesman MM. Revertants of a Chinese hamster ovary cell mutant with an altered beta-tubulin: evidence that the altered tubulin confers both colcemid resistance and temperature sensitivity on the cell. Molecular and Cellular Biology. 2: 720-9. PMID 14582168 DOI: 10.1128/Mcb.2.6.720 |
0.518 |
|
| 2003 |
Hari M, Yang H, Zeng C, Canizales M, Cabral F. Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel. Cell Motility and the Cytoskeleton. 56: 45-56. PMID 12905530 DOI: 10.1002/Cm.10132 |
0.722 |
|
| 2003 |
Hari M, Wang Y, Veeraraghavan S, Cabral F. Mutations in alpha- and beta-tubulin that stabilize microtubules and confer resistance to colcemid and vinblastine. Molecular Cancer Therapeutics. 2: 597-605. PMID 12883031 |
0.518 |
|
| 2003 |
Barlow SB, Gonzalez-Garay ML, Cabral F. Paclitaxel-dependent mutants have severely reduced microtubule assembly and reduced tubulin synthesis. Journal of Cell Science. 115: 3469-78. PMID 12154077 DOI: 10.1242/jcs.115.17.3469 |
0.492 |
|
| 2001 |
Newman RA, Yang J, Raymond M, Finlay V, Cabral F, Vourloumis D, Stephens LC, Troncoso P, Wu X, Logothetis CJ, Nicolaou KC, Navone NM. Antitumor efficacy of 26-fluoroepothilone B against human prostate cancer xenografts. Cancer Chemotherapy and Pharmacology. 48: 319-26. PMID 11710633 DOI: 10.1007/S002800100323 |
0.323 |
|
| 2001 |
Cabral F. Factors determining cellular mechanisms of resistance to antimitotic drugs Drug Resistance Updates. 4: 3-8. PMID 11512151 DOI: 10.1054/Drup.2000.0172 |
0.496 |
|
| 1999 |
Gonzalez-Garay ML, Chang L, Blade K, Menick DR, Cabral F. A beta-tubulin leucine cluster involved in microtubule assembly and paclitaxel resistance. The Journal of Biological Chemistry. 274: 23875-82. PMID 10446152 DOI: 10.1074/Jbc.274.34.23875 |
0.577 |
|
| 1999 |
Cabral F, Trimble E, Reed E, Sarosy G. Future directions with taxane therapy. Hematology-Oncology Clinics of North America. 13: 21-41. PMID 10080068 DOI: 10.1016/S0889-8588(05)70152-0 |
0.334 |
|
| 1996 |
Gonzalez-Garay ML, Cabral F. alpha-Tubulin limits its own synthesis: evidence for a mechanism involving translational repression. Journal of Cell Biology. 135: 1525-1534. PMID 8978820 DOI: 10.1083/Jcb.135.6.1525 |
0.308 |
|
| 1996 |
Minotti AM, Stiernberg CM, Cabral F. Inhibition of cholesteatoma migration in vitro with all-trans retinoic acid. Otolaryngology-Head and Neck Surgery. 114: 768-776. PMID 8643301 DOI: 10.1016/S0194-5998(96)70100-6 |
0.307 |
|
| 1995 |
Gonzalez‐Garay ML, Cabral F. Overexpression of an epitope‐ tagged β‐tubulin in Chinese hamster ovary cells causes an increase in endogenous α‐tubulin synthesis Cytoskeleton. 31: 259-272. PMID 7553913 DOI: 10.1002/Cm.970310403 |
0.406 |
|
| 1991 |
Barlow SB, Cabral F. Alterations in microtubule assembly caused by the microtubule-active drug LY195448. Cytoskeleton. 19: 9-17. PMID 1863984 DOI: 10.1002/Cm.970190103 |
0.599 |
|
| 1991 |
Cabral F, Barlow SB. Resistance to antimitotic agents as genetic probes of microtubule structure and function. Pharmacology & Therapeutics. 52: 159-171. PMID 1818334 DOI: 10.1016/0163-7258(91)90006-8 |
0.595 |
|
| 1990 |
Minotti AM, Loeb LM, Cook R, Boggs BA, Cabral F. Identification of methionine-containing tryptic peptides of unstable β-tubulin separated by reverse-phase high-performance liquid chromatography Analytical Biochemistry. 184: 28-34. PMID 2321756 DOI: 10.1016/0003-2697(90)90006-U |
0.426 |
|
| 1989 |
Cabral F, Barlow SB. Mechanisms by which mammalian cells acquire resistance to drugs that affect microtubule assembly. The Faseb Journal. 3: 1593-1599. PMID 2646163 DOI: 10.1096/Fasebj.3.5.2646163 |
0.499 |
|
| 1989 |
Schibler MJ, Barlow SB, Cabral F. Elimination of permeability mutants from selections for drug resistance in mammalian cells. The Faseb Journal. 3: 163-168. PMID 2563346 DOI: 10.1096/Fasebj.3.2.2563346 |
0.48 |
|
| 1987 |
Boggs B, Cabral F. Mutations affecting assembly and stability of tubulin: evidence for a nonessential beta-tubulin in CHO cells Molecular and Cellular Biology. 7: 2700-2707. PMID 3670290 DOI: 10.1128/Mcb.7.8.2700 |
0.41 |
|
| 1986 |
Brady RC, Schibler MJ, Cabral F. [22] Isolation of mitotic spindles from mammalian cells Methods in Enzymology. 134: 217-225. PMID 3821562 DOI: 10.1016/0076-6879(86)34090-4 |
0.383 |
|
| 1986 |
Brady RC, Cabral F, Dedman JR. Identification of a 52-kD calmodulin-binding protein associated with the mitotic spindle apparatus in mammalian cells Journal of Cell Biology. 103: 1855-1861. PMID 3536955 DOI: 10.1083/Jcb.103.5.1855 |
0.39 |
|
| 1986 |
Cabral FR, Brady RC, Schibler MJ. A Mechanism of Cellular Resistance to Drugs that Interfere with Microtubule Assemblya Annals of the New York Academy of Sciences. 466: 745-756. PMID 2873781 DOI: 10.1111/J.1749-6632.1986.Tb38456.X |
0.503 |
|
| 1986 |
Schibler MJ, Cabral F. Taxol-dependent mutants of Chinese hamster ovary cells with alterations in alpha- and beta-tubulin. Journal of Cell Biology. 102: 1522-1531. PMID 2870070 DOI: 10.1083/Jcb.102.4.1522 |
0.541 |
|
| 1983 |
Abraham I, Marcus M, Cabral F, Gottesman MM. Mutations in alpha- and beta-tubulin affect spindle formation in Chinese hamster ovary cells. The Journal of Cell Biology. 97: 1055-61. PMID 6619186 DOI: 10.1083/Jcb.97.4.1055 |
0.473 |
|
| 1983 |
Cabral F, Wible L, Brenner S, Brinkley BR. Taxol-requiring mutant of Chinese hamster ovary cells with impaired mitotic spindle assembly. Journal of Cell Biology. 97: 30-39. PMID 6134737 DOI: 10.1083/Jcb.97.1.30 |
0.496 |
|
| 1981 |
Steinert PM, Idler WW, Cabral F, Gottesman MM, Goldman RD. In vitro assembly of homopolymer and copolymer filaments from intermediate filament subunits of muscle and fibroblastic cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 3692-6. PMID 6943573 DOI: 10.1073/Pnas.78.6.3692 |
0.352 |
|
| 1981 |
Cabral F, Abraham I, Gottesman MM. Isolation of a taxol-resistant Chinese hamster ovary cell mutant that has an alteration in alpha-tubulin. Proceedings of the National Academy of Sciences of the United States of America. 78: 4388-91. PMID 6117076 DOI: 10.1073/Pnas.78.7.4388 |
0.449 |
|
| 1980 |
Cabral F, Willingham MC, Gottesman MM. Ultrastructural localization to 10 nm filaments of an insoluble 58K protein in cultured fibroblasts. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 28: 653-62. PMID 7391554 DOI: 10.1177/28.7.7391554 |
0.34 |
|
| 1980 |
Cabral F, Sobel ME, Gottesman MM. CHO mutants resistant to colchicine, colcemid or griseofulvin have an altered β-tubulin Cell. 20: 29-36. PMID 7388944 DOI: 10.1016/0092-8674(80)90231-7 |
0.541 |
|
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