| Year |
Citation |
Score |
| 2024 |
Yen YC, Li Y, Chen CL, Klose T, Watts VJ, Dessauer CW, Tesmer JJG. Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia. Nature Structural & Molecular Biology. PMID 38589608 DOI: 10.1038/s41594-024-01263-0 |
0.337 |
|
| 2023 |
Yen YC, Li Y, Chen CL, Klose T, Watts VJ, Dessauer CW, Tesmer JJG. Isoform Specific Regulation of Adenylyl Cyclase 5 by Gβγ. Biorxiv : the Preprint Server For Biology. PMID 37205557 DOI: 10.1101/2023.05.02.539090 |
0.343 |
|
| 2022 |
Baldwin TA, Li Y, Marsden AN, Rinné S, Garza-Carbajal A, Schindler RFR, Zhang M, Garcia MA, Venna VR, Decher N, Brand T, Dessauer CW. POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium channel TREK-1 in heart. Embo Reports. e55208. PMID 36254885 DOI: 10.15252/embr.202255208 |
0.321 |
|
| 2022 |
Qi C, Lavriha P, Mehta V, Khanppnavar B, Mohammed I, Li Y, Lazaratos M, Schaefer JV, Dreier B, Plückthun A, Bondar AN, Dessauer CW, Korkhov VM. Structural basis of adenylyl cyclase 9 activation. Nature Communications. 13: 1045. PMID 35210418 DOI: 10.1038/s41467-022-28685-y |
0.348 |
|
| 2021 |
Ostrom KF, LaVigne JE, Brust TF, Seifert R, Dessauer CW, Watts VJ, Ostrom RS. Physiological Roles of Mammalian Transmembrane Adenylyl Cyclase Isoforms. Physiological Reviews. PMID 34698552 DOI: 10.1152/physrev.00013.2021 |
0.311 |
|
| 2020 |
Carbajal AG, Bavencoffe A, Walters ET, Dessauer CW. Depolarization-dependent C-Raf signaling promotes hyperexcitability and reduces opioid sensitivity of isolated nociceptors after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32690613 DOI: 10.1523/Jneurosci.0810-20.2020 |
0.329 |
|
| 2020 |
Lazar AM, Irannejad R, Baldwin TA, Sundaram AB, Gutkind JS, Inoue A, Dessauer CW, Von Zastrow M. G protein-regulated endocytic trafficking of adenylyl cyclase type 9. Elife. 9. PMID 32515353 DOI: 10.7554/Elife.58039 |
0.446 |
|
| 2020 |
Lazar AM, Irannejad R, Baldwin TA, Sundaram AB, Gutkind JS, Inoue A, Dessauer CW, Zastrow MV. Author response: G protein-regulated endocytic trafficking of adenylyl cyclase type 9 Elife. DOI: 10.7554/Elife.58039.Sa2 |
0.384 |
|
| 2020 |
Yakubovich D, Kahanovitch U, Tabak G, Keren Raifman T, Tsemakhovich V, Ranjan Tripathy D, Dessauer CW, Hirsch JA, Dascal N. Gβγ Activates GIRK2 with Low-Micromolar Affinity with Distinct Activation Pattern Compared to GIRK1/2 Biophysical Journal. 118: 270a. DOI: 10.1016/J.Bpj.2019.11.1557 |
0.311 |
|
| 2019 |
Marsden AN, Dessauer CW. Nanometric targeting of type 9 adenylyl cyclase in heart. Biochemical Society Transactions. PMID 31769471 DOI: 10.1042/Bst20190227 |
0.375 |
|
| 2019 |
Doyle TB, Muntean BS, Ejendal KF, Hayes MP, Soto-Velasquez M, Martemyanov KA, Dessauer CW, Hu CD, Watts VJ. Identification of Novel Adenylyl Cyclase 5 (AC5) Signaling Networks in D and D Medium Spiny Neurons using Bimolecular Fluorescence Complementation Screening. Cells. 8. PMID 31752385 DOI: 10.3390/Cells8111468 |
0.417 |
|
| 2019 |
Li Y, Hof T, Baldwin TA, Chen L, Kass RS, Dessauer CW. Regulation of I Potassium Current by Isoproterenol in Adult Cardiomyocytes Requires Type 9 Adenylyl Cyclase. Cells. 8. PMID 31461851 DOI: 10.3390/Cells8090981 |
0.395 |
|
| 2019 |
Baldwin TA, Li Y, Brand CS, Watts VJ, Dessauer CW. Insights Into The Regulatory Properties of Human Adenylyl Cyclase Type 9. Molecular Pharmacology. PMID 30696718 DOI: 10.1124/Mol.118.114595 |
0.42 |
|
| 2019 |
Dessauer CW, Ostrom R, Seifert R, Watts VJ. Adenylyl cyclases (ACs) (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f257/2019.4 |
0.337 |
|
| 2018 |
Ferré S, Bonaventura J, Zhu W, Hatcher-Solis C, Taura J, Quiroz C, Cai NS, Moreno E, Casadó-Anguera V, Kravitz AV, Thompson KR, Tomasi DG, Navarro G, Cordomí A, Pardo L, ... ... Dessauer CW, et al. Essential Control of the Function of the Striatopallidal Neuron by Pre-coupled Complexes of Adenosine A-Dopamine D Receptor Heterotetramers and Adenylyl Cyclase. Frontiers in Pharmacology. 9: 243. PMID 29686613 DOI: 10.3389/Fphar.2018.00243 |
0.306 |
|
| 2018 |
Navarro G, Cordomí A, Casadó-Anguera V, Moreno E, Cai NS, Cortés A, Canela EI, Dessauer CW, Casadó V, Pardo L, Lluís C, Ferré S. Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase. Nature Communications. 9: 1242. PMID 29593213 DOI: 10.1038/S41467-018-03522-3 |
0.405 |
|
| 2018 |
Baldwin TA, Dessauer CW. Function of Adenylyl Cyclase in Heart: the AKAP Connection. Journal of Cardiovascular Development and Disease. 5. PMID 29367580 DOI: 10.3390/Jcdd5010002 |
0.418 |
|
| 2017 |
Dessauer CW. Shining a light on GPCR complexes. The Journal of Biological Chemistry. 292: 14290-14291. PMID 28842475 DOI: 10.1074/Jbc.H117.797100 |
0.383 |
|
| 2017 |
Li Y, Baldwin TA, Wang Y, Subramaniam J, Carbajal AG, Brand CS, Cunha SR, Dessauer CW. Loss of type 9 adenylyl cyclase triggers reduced phosphorylation of Hsp20 and diastolic dysfunction. Scientific Reports. 7: 5522. PMID 28717248 DOI: 10.1038/S41598-017-05816-W |
0.367 |
|
| 2017 |
Dessauer CW, Watts VJ, Ostrom RS, Conti M, Dove S, Seifert R. International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases. Pharmacological Reviews. 69: 93-139. PMID 28255005 DOI: 10.1124/Pr.116.013078 |
0.417 |
|
| 2017 |
Brust TF, Alongkronrusmee D, Soto-Velasquez M, Baldwin TA, Ye Z, Dai M, Dessauer CW, van Rijn RM, Watts VJ. Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties. Science Signaling. 10. PMID 28223412 DOI: 10.1126/Scisignal.Aah5381 |
0.371 |
|
| 2016 |
Bavencoffe A, Li Y, Wu Z, Yang Q, Herrera J, Kennedy EJ, Walters ET, Dessauer CW. Persistent Electrical Activity in Primary Nociceptors after Spinal Cord Injury Is Maintained by Scaffolded Adenylyl Cyclase and Protein Kinase A and Is Associated with Altered Adenylyl Cyclase Regulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1660-8. PMID 26843647 DOI: 10.1523/Jneurosci.0895-15.2016 |
0.361 |
|
| 2015 |
Xie K, Masuho I, Shih CC, Cao Y, Sasaki K, Lai CW, Han PL, Ueda H, Dessauer CW, Ehrlich ME, Xu B, Willardson BM, Martemyanov KA. Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling. Elife. 4. PMID 26613416 DOI: 10.7554/Elife.10451 |
0.447 |
|
| 2015 |
Yakubovich D, Berlin S, Kahanovitch U, Rubinstein M, Farhy-Tselnicker I, Styr B, Keren-Raifman T, Dessauer CW, Dascal N. A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ. Plos Computational Biology. 11: e1004598. PMID 26544551 DOI: 10.1371/Journal.Pcbi.1004598 |
0.417 |
|
| 2015 |
Brand CS, Sadana R, Malik S, Smrcka AV, Dessauer CW. Adenylyl Cyclase 5 Regulation by Gβγ Involves Isoform-Specific Use of Multiple Interaction Sites. Molecular Pharmacology. 88: 758-67. PMID 26206488 DOI: 10.1124/Mol.115.099556 |
0.466 |
|
| 2015 |
Xie K, Masuho I, Shih C, Cao Y, Sasaki K, Lai CWJ, Han P, Ueda H, Dessauer CW, Ehrlich ME, Xu B, Willardson BM, Martemyanov KA. Author response: Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling Elife. DOI: 10.7554/Elife.10451.011 |
0.356 |
|
| 2014 |
Kahanovitch U, Tsemakhovich V, Berlin S, Rubinstein M, Styr B, Castel R, Peleg S, Tabak G, Dessauer CW, Ivanina T, Dascal N. Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1. The Journal of Physiology. 592: 5373-90. PMID 25384780 DOI: 10.1113/Jphysiol.2014.283218 |
0.47 |
|
| 2014 |
Dvir M, Strulovich R, Sachyani D, Ben-Tal Cohen I, Haitin Y, Dessauer C, Pongs O, Kass R, Hirsch JA, Attali B. Long QT mutations at the interface between KCNQ1 helix C and KCNE1 disrupt I(KS) regulation by PKA and PIP₂. Journal of Cell Science. 127: 3943-55. PMID 25037568 DOI: 10.1242/Jcs.147033 |
0.369 |
|
| 2014 |
Farhy Tselnicker I, Tsemakhovich V, Rishal I, Kahanovitch U, Dessauer CW, Dascal N. Dual regulation of G proteins and the G-protein-activated K+ channels by lithium. Proceedings of the National Academy of Sciences of the United States of America. 111: 5018-23. PMID 24639496 DOI: 10.1073/Pnas.1316425111 |
0.449 |
|
| 2014 |
Tselnicker IF, Tsemakhovich V, Rishal I, Dessauer CW, Dascal N. Dual Regulation of G Proteins and the G Protein-Activated Potassium Channels (GIRK) by Lithium Biophysical Journal. 106: 433a. DOI: 10.1016/J.Bpj.2013.11.2436 |
0.457 |
|
| 2013 |
Conley JM, Brand CS, Bogard AS, Pratt EP, Xu R, Hockerman GH, Ostrom RS, Dessauer CW, Watts VJ. Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor. The Journal of Pharmacology and Experimental Therapeutics. 347: 276-87. PMID 24008337 DOI: 10.1124/Jpet.113.207449 |
0.321 |
|
| 2013 |
Brand CS, Hocker HJ, Gorfe AA, Cavasotto CN, Dessauer CW. Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds. The Journal of Pharmacology and Experimental Therapeutics. 347: 265-75. PMID 24006339 DOI: 10.1124/Jpet.113.208157 |
0.373 |
|
| 2013 |
Efendiev R, Bavencoffe A, Hu H, Zhu MX, Dessauer CW. Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel. The Journal of Biological Chemistry. 288: 3929-37. PMID 23264624 DOI: 10.1074/Jbc.M112.428144 |
0.444 |
|
| 2013 |
Scott JD, Dessauer CW, Taskén K. Creating order from chaos: Cellular regulation by kinase anchoring Annual Review of Pharmacology and Toxicology. 53: 187-210. PMID 23043438 DOI: 10.1146/Annurev-Pharmtox-011112-140204 |
0.435 |
|
| 2013 |
Dvir M, Shaham D, Ben-Tal Cohen I, Strulovitz R, Haitin Y, Dessauer C, Kass R, Hirsch J, Attali B. The Distal Kcne1 C-Terminus is Crucial for Yotiao Mediated Pka-Dependent Phosphorylation of KCNQ1 Biophysical Journal. 104: 210a. DOI: 10.1016/J.Bpj.2012.11.1186 |
0.368 |
|
| 2012 |
Xie K, Masuho I, Brand C, Dessauer CW, Martemyanov KA. The complex of G protein regulator RGS9-2 and Gβ(5) controls sensitization and signaling kinetics of type 5 adenylyl cyclase in the striatum. Science Signaling. 5: ra63. PMID 22932702 DOI: 10.1126/Scisignal.2002922 |
0.481 |
|
| 2012 |
Li Y, Chen L, Kass RS, Dessauer CW. The A-kinase anchoring protein Yotiao facilitates complex formation between adenylyl cyclase type 9 and the IKs potassium channel in heart. The Journal of Biological Chemistry. 287: 29815-24. PMID 22778270 DOI: 10.1074/Jbc.M112.380568 |
0.419 |
|
| 2012 |
Pulliainen AT, Pieles K, Brand CS, Hauert B, Böhm A, Quebatte M, Wepf A, Gstaiger M, Aebersold R, Dessauer CW, Dehio C. Bacterial effector binds host cell adenylyl cyclase to potentiate Gαs-dependent cAMP production. Proceedings of the National Academy of Sciences of the United States of America. 109: 9581-6. PMID 22635269 DOI: 10.1073/Pnas.1117651109 |
0.456 |
|
| 2012 |
Ejendal KF, Dessauer CW, Hébert TE, Watts VJ. Dopamine D(2) Receptor-Mediated Heterologous Sensitization of AC5 Requires Signalosome Assembly. Journal of Signal Transduction. 2012: 210324. PMID 22523680 DOI: 10.1155/2012/210324 |
0.336 |
|
| 2012 |
Yakubovich D, Berlin S, Rubinstein M, Kahanovich U, Dessauer CW, Dascal N. Preferential Association with Gβγ Over Gα Governs the Activity of a G Protein-Activated K+ Channel Biophysical Journal. 102: 538a. DOI: 10.1016/J.Bpj.2011.11.2939 |
0.404 |
|
| 2012 |
Thakur D, Dessauer C, Zhu MX. Differential Modulation of Detergents on Single Channel Activity of TRPC4/C5 Biophysical Journal. 102: 535a-536a. DOI: 10.1016/J.Bpj.2011.11.2926 |
0.404 |
|
| 2011 |
Efendiev R, Dessauer CW. A kinase-anchoring proteins and adenylyl cyclase in cardiovascular physiology and pathology. Journal of Cardiovascular Pharmacology. 58: 339-44. PMID 21978991 DOI: 10.1097/Fjc.0B013E31821Bc3F0 |
0.404 |
|
| 2011 |
Berlin S, Tsemakhovich VA, Castel R, Ivanina T, Dessauer CW, Keren-Raifman T, Dascal N. Two distinct aspects of coupling between Gα(i) protein and G protein-activated K+ channel (GIRK) revealed by fluorescently labeled Gα(i3) protein subunits. The Journal of Biological Chemistry. 286: 33223-35. PMID 21795707 DOI: 10.1074/Jbc.M111.271056 |
0.424 |
|
| 2011 |
Berlin S, Tsemakhovich V, Dessauer CW, Dascal N. Deficient Regulation of Gbetagamma Effectors by Fluorescently Labeled Galpha i3 Subunits Reveals Distinct Aspects of Coupling to GIRK and Cav2.2 Channels Biophysical Journal. 100: 258a. DOI: 10.1016/J.Bpj.2010.12.1624 |
0.467 |
|
| 2010 |
Tselnicker I, Tsemakhovich VA, Dessauer CW, Dascal N. Stargazin modulates neuronal voltage-dependent Ca(2+) channel Ca(v)2.2 by a Gbetagamma-dependent mechanism. The Journal of Biological Chemistry. 285: 20462-71. PMID 20435886 DOI: 10.1074/Jbc.M110.121277 |
0.375 |
|
| 2010 |
Efendiev R, Samelson BK, Nguyen BT, Phatarpekar PV, Baameur F, Scott JD, Dessauer CW. AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors. The Journal of Biological Chemistry. 285: 14450-8. PMID 20231277 DOI: 10.1074/Jbc.M110.109769 |
0.443 |
|
| 2010 |
Vayttaden SJ, Friedman J, Tran TM, Rich TC, Dessauer CW, Clark RB. Quantitative modeling of GRK-mediated beta2AR regulation. Plos Computational Biology. 6: e1000647. PMID 20098494 DOI: 10.1371/Journal.Pcbi.1000647 |
0.344 |
|
| 2010 |
Berlin S, Keren-Raifman T, Castel R, Rubinstein M, Dessauer CW, Ivanina T, Dascal N. G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K+ channel (GIRK). The Journal of Biological Chemistry. 285: 6179-85. PMID 20018875 DOI: 10.1074/Jbc.M109.085944 |
0.41 |
|
| 2009 |
Sadana R, Dascal N, Dessauer CW. N terminus of type 5 adenylyl cyclase scaffolds Gs heterotrimer. Molecular Pharmacology. 76: 1256-64. PMID 19783621 DOI: 10.1124/Mol.109.058370 |
0.493 |
|
| 2009 |
Dessauer CW. Adenylyl cyclase--A-kinase anchoring protein complexes: the next dimension in cAMP signaling. Molecular Pharmacology. 76: 935-41. PMID 19684092 DOI: 10.1124/Mol.109.059345 |
0.411 |
|
| 2009 |
Kapiloff MS, Piggott LA, Sadana R, Li J, Heredia LA, Henson E, Efendiev R, Dessauer CW. An adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP levels in cardiac myocytes. The Journal of Biological Chemistry. 284: 23540-6. PMID 19574217 DOI: 10.1074/Jbc.M109.030072 |
0.431 |
|
| 2009 |
Rubinstein M, Peleg S, Berlin S, Brass D, Keren-Raifman T, Dessauer CW, Ivanina T, Dascal N. Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GalphaiGDP and Gbetagamma. The Journal of Physiology. 587: 3473-91. PMID 19470775 DOI: 10.1113/Jphysiol.2009.173229 |
0.46 |
|
| 2009 |
Sadana R, Dessauer CW. Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies. Neuro-Signals. 17: 5-22. PMID 18948702 DOI: 10.1159/000166277 |
0.424 |
|
| 2009 |
Yakubovich D, Rishal I, Dessauer CW, Dascal N. Amplitude histogram-based method of analysis of patch clamp recordings that involve extreme changes in channel activity levels. Journal of Molecular Neuroscience : Mn. 37: 201-11. PMID 18622586 DOI: 10.1007/S12031-008-9117-Z |
0.341 |
|
| 2009 |
Rubinstein M, Berlin S, Keren-Raifman T, Peleg S, Dessauer C, Ivanina T, Dascal N. Diverse Regulation of the Neuronal G-Protein Gated K+ Channel (GIRK), GIRK1 and GIRK2 by Gα and Gβγ Biophysical Journal. 96: 464a. DOI: 10.1016/J.Bpj.2008.12.2388 |
0.486 |
|
| 2008 |
Piggott LA, Bauman AL, Scott JD, Dessauer CW. The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain. Proceedings of the National Academy of Sciences of the United States of America. 105: 13835-40. PMID 18772391 DOI: 10.1073/Pnas.0712100105 |
0.432 |
|
| 2008 |
Gu S, Anton A, Salim S, Blumer KJ, Dessauer CW, Heximer SP. Alternative translation initiation of human regulators of G-protein signaling-2 yields a set of functionally distinct proteins. Molecular Pharmacology. 73: 1-11. PMID 17901199 DOI: 10.1124/Mol.107.036285 |
0.419 |
|
| 2007 |
Gao X, Sadana R, Dessauer CW, Patel TB. Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits. The Journal of Biological Chemistry. 282: 294-302. PMID 17110384 DOI: 10.1074/Jbc.M607522200 |
0.466 |
|
| 2007 |
Gao X, Sadana R, Dessauer CW, Patel TB. CONDITIONAL STIMULATION OF TYPE V AND VI ADENYLYL CYCLASES BY G PROTEIN βγ SUBUNITS The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A430-D |
0.406 |
|
| 2006 |
Bauman AL, Soughayer J, Nguyen BT, Willoughby D, Carnegie GK, Wong W, Hoshi N, Langeberg LK, Cooper DM, Dessauer CW, Scott JD. Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes. Molecular Cell. 23: 925-31. PMID 16973443 DOI: 10.1016/J.Molcel.2006.07.025 |
0.463 |
|
| 2006 |
Sayner SL, Alexeyev M, Dessauer CW, Stevens T. Soluble adenylyl cyclase reveals the significance of cAMP compartmentation on pulmonary microvascular endothelial cell barrier. Circulation Research. 98: 675-81. PMID 16469954 DOI: 10.1161/01.Res.0000209516.84815.3E |
0.327 |
|
| 2005 |
Nguyen BT, Dessauer CW. Relaxin stimulates cAMP production in MCF-7 cells upon overexpression of type V adenylyl cyclase. Annals of the New York Academy of Sciences. 1041: 296-9. PMID 15956721 DOI: 10.1196/Annals.1282.044 |
0.376 |
|
| 2005 |
Dessauer CW, Nguyen BT. Relaxin stimulates multiple signaling pathways: activation of cAMP, PI3K, and PKCzeta in THP-1 cells. Annals of the New York Academy of Sciences. 1041: 272-9. PMID 15956717 DOI: 10.1196/Annals.1282.040 |
0.369 |
|
| 2005 |
Nguyen BT, Dessauer CW. Relaxin stimulates protein kinase C zeta translocation: requirement for cyclic adenosine 3',5'-monophosphate production. Molecular Endocrinology (Baltimore, Md.). 19: 1012-23. PMID 15604116 DOI: 10.1210/Me.2004-0279 |
0.429 |
|
| 2005 |
Chen-Goodspeed M, Lukan AN, Dessauer CW. Modeling of Galpha(s) and Galpha(i) regulation of human type V and VI adenylyl cyclase. The Journal of Biological Chemistry. 280: 1808-16. PMID 15545274 DOI: 10.1074/Jbc.M409172200 |
0.386 |
|
| 2004 |
Salim S, Dessauer CW. Analysis of the interaction between RGS2 and adenylyl cyclase Methods in Enzymology. 390: 83-99. PMID 15488172 DOI: 10.1016/S0076-6879(04)90006-7 |
0.498 |
|
| 2004 |
Ivanina T, Varon D, Peleg S, Rishal I, Porozov Y, Dessauer CW, Keren-Raifman T, Dascal N. Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel. The Journal of Biological Chemistry. 279: 17260-8. PMID 14963032 DOI: 10.1074/Jbc.M313425200 |
0.506 |
|
| 2003 |
Ivanina T, Rishal I, Varon D, Mullner C, Frohnwieser-Steinecke B, Schreibmayer W, Dessauer CW, Dascal N. Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel. The Journal of Biological Chemistry. 278: 29174-83. PMID 12743112 DOI: 10.1074/Jbc.M304518200 |
0.425 |
|
| 2003 |
Salim S, Sinnarajah S, Kehrl JH, Dessauer CW. Identification of RGS2 and type V adenylyl cyclase interaction sites. The Journal of Biological Chemistry. 278: 15842-9. PMID 12604604 DOI: 10.1074/Jbc.M210663200 |
0.452 |
|
| 2003 |
Nguyen BT, Yang L, Sanborn BM, Dessauer CW. Phosphoinositide 3-kinase activity is required for biphasic stimulation of cyclic adenosine 3',5'-monophosphate by relaxin. Molecular Endocrinology (Baltimore, Md.). 17: 1075-84. PMID 12595573 DOI: 10.1210/Me.2002-0284 |
0.418 |
|
| 2003 |
Müllner C, Yakubovich D, Dessauer CW, Platzer D, Schreibmayer W. Single channel analysis of the regulation of GIRK1/GIRK4 channels by protein phosphorylation. Biophysical Journal. 84: 1399-409. PMID 12547819 DOI: 10.1016/S0006-3495(03)74954-6 |
0.459 |
|
| 2003 |
Rishal I, Keren-Raifman T, Yakubovich D, Ivanina T, Dessauer CW, Slepak VZ, Dascal N. Na+ promotes the dissociation between Galpha GDP and Gbeta gamma, activating G protein-gated K+ channels. The Journal of Biological Chemistry. 278: 3840-5. PMID 12488455 DOI: 10.1074/Jbc.C200605200 |
0.421 |
|
| 2002 |
Dessauer CW, Chen-Goodspeed M, Chen J. Mechanism of Galpha i-mediated inhibition of type V adenylyl cyclase. The Journal of Biological Chemistry. 277: 28823-9. PMID 12058044 DOI: 10.1074/Jbc.M203962200 |
0.468 |
|
| 2002 |
Peleg S, Varon D, Ivanina T, Dessauer CW, Dascal N. G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK. Neuron. 33: 87-99. PMID 11779482 DOI: 10.1016/S0896-6273(01)00567-0 |
0.413 |
|
| 2002 |
Dessauer CW. Kinetic analysis of the action of P-site analogs. Methods in Enzymology. 345: 112-26. PMID 11665599 DOI: 10.1016/S0076-6879(02)45011-2 |
0.445 |
|
| 2001 |
Shi CS, Lee SB, Sinnarajah S, Dessauer CW, Rhee SG, Kehrl JH. Regulator of G-protein signaling 3 (RGS3) inhibits Gbeta1gamma 2-induced inositol phosphate production, mitogen-activated protein kinase activation, and Akt activation. The Journal of Biological Chemistry. 276: 24293-300. PMID 11294858 DOI: 10.1074/jbc.M100089200 |
0.391 |
|
| 2001 |
Sinnarajah S, Dessauer CW, Srikumar D, Chen J, Yuen J, Yilma S, Dennis JC, Morrison EE, Vodyanoy V, Kehrl JH. RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III. Nature. 409: 1051-5. PMID 11234015 DOI: 10.1038/35059104 |
0.392 |
|
| 2000 |
Tesmer JJ, Dessauer CW, Sunahara RK, Murray LD, Johnson RA, Gilman AG, Sprang SR. Molecular basis for P-site inhibition of adenylyl cyclase. Biochemistry. 39: 14464-71. PMID 11087399 DOI: 10.1021/Bi0015562 |
0.69 |
|
| 2000 |
Scheschonka A, Dessauer CW, Sinnarajah S, Chidiac P, Shi CS, Kehrl JH. RGS3 Is a GTPase-Activating Protein for Giα and Gqα and a Potent Inhibitor of Signaling by GTPase-Deficient Forms of Gqα and G11α Molecular Pharmacology. 58: 719-728. PMID 10999941 DOI: 10.1124/Mol.58.4.719 |
0.483 |
|
| 2000 |
Yakubovich D, Pastushenko V, Bitler A, Dessauer CW, Dascal N. Slow modal gating of single G protein-activated K+ channels expressed in Xenopus oocytes. The Journal of Physiology. 524: 737-55. PMID 10790155 DOI: 10.1111/J.1469-7793.2000.00737.X |
0.359 |
|
| 1999 |
Doronin S, Murray L, Dessauer CW, Johnson RA. Covalent Labeling of Adenylyl Cyclase Cytosolic Domains with γ-Methylimidazole-2′,5′-dideoxy-[γ-32P]3′-ATP and the Mechanism for P-site-mediated Inhibition Journal of Biological Chemistry. 274: 34745-34750. PMID 10574943 DOI: 10.1074/Jbc.274.49.34745 |
0.363 |
|
| 1999 |
Johnson RA, Shoshani I, Dessauer C, Gosselin G. Enzymatic preparation of 32P-labeled beta-L-2',3',-dd-5'ATP and its use as a high-affinity, conformation-specific ligand for labeling adenylyl cyclases. Nucleosides & Nucleotides. 18: 839-42. PMID 10432690 DOI: 10.1080/15257779908041575 |
0.305 |
|
| 1999 |
Dessauer CW, Tesmer JJ, Sprang SR, Gilman AG. The interactions of adenylate cyclases with P-site inhibitors. Trends in Pharmacological Sciences. 20: 205-10. PMID 10354616 DOI: 10.1016/S0165-6147(99)01310-3 |
0.586 |
|
| 1999 |
Zhong J, Dessauer CW, Keef KD, Hume JR. Regulation of L-type Ca2+ channels in rabbit portal vein by G protein α(s) and βγ subunits Journal of Physiology. 517: 109-120. PMID 10226153 DOI: 10.1111/J.1469-7793.1999.0109Z.X |
0.419 |
|
| 1999 |
Doronin S, Dessauer C, Johnson RA. Direct photoaffinity labeling of individual cytosolic domains of adenylyl cyclase by [32P]2'-deoxy-3'-AMP and [alpha-32P]5'-ATP. The Journal of Biological Chemistry. 273: 32416-20. PMID 9829971 DOI: 10.1074/Jbc.273.49.32416 |
0.395 |
|
| 1998 |
Dessauer CW, Tesmer JJ, Sprang SR, Gilman AG. Identification of a Gialpha binding site on type V adenylyl cyclase. The Journal of Biological Chemistry. 273: 25831-9. PMID 9748257 DOI: 10.1074/Jbc.273.40.25831 |
0.61 |
|
| 1997 |
Dessauer CW, Gilman AG. The catalytic mechanism of mammalian adenylyl cyclase: Equilibrium binding and kinetic analysis of P-site inhibition Journal of Biological Chemistry. 272: 27787-27795. PMID 9346923 DOI: 10.1074/Jbc.272.44.27787 |
0.585 |
|
| 1997 |
Dessauer CW, Scully TT, Gilman AG. Interactions of forskolin and ATP with the cytosolic domains of mammalian adenylyl cyclase Journal of Biological Chemistry. 272: 22272-22277. PMID 9268376 DOI: 10.1074/Jbc.272.35.22272 |
0.609 |
|
| 1997 |
Sunahara RK, Dessauer CW, Whisnant RE, Kleuss C, Gilman AG. Interaction of G(sα) with the cytosolic domains of mammalian adenylyl cyclase Journal of Biological Chemistry. 272: 22265-22271. PMID 9268375 DOI: 10.1074/Jbc.272.35.22265 |
0.718 |
|
| 1996 |
Dessauer CW, Posner BA, Gilman AG. Visualizing signal transduction: Receptors, G-proteins, and adenylate cyclases Clinical Science. 91: 527-537. PMID 8942391 DOI: 10.1042/Cs0910527 |
0.663 |
|
| 1996 |
Doupnik CA, Dessauer CW, Slepak VZ, Gilman AG, Davidson N, Lester HA. Time resolved kinetics of direct G beta 1 gamma 2 interactions with the carboxyl terminus of Kir3.4 inward rectifier K+ channel subunits. Neuropharmacology. 35: 923-31. PMID 8938723 DOI: 10.1016/0028-3908(96)00125-6 |
0.615 |
|
| 1996 |
Sunahara RK, Dessauer CW, Gilman AG. Complexity and diversity of mammalian adenylyl cyclases Annual Review of Pharmacology and Toxicology. 36: 461-480. PMID 8725398 DOI: 10.1146/Annurev.Pa.36.040196.002333 |
0.734 |
|
| 1996 |
Whisnant RE, Gilman AG, Dessauer CW. Interaction of the two cytosolic domains of mammalian adenylyl cyclase Proceedings of the National Academy of Sciences of the United States of America. 93: 6621-6625. PMID 8692867 DOI: 10.1073/Pnas.93.13.6621 |
0.607 |
|
| 1996 |
Dessauer CW, Gilman AG. Purification and characterization of a soluble form of mammalian adenylyl cyclase Journal of Biological Chemistry. 271: 16967-16974. PMID 8663304 DOI: 10.1074/Jbc.271.28.16967 |
0.624 |
|
| 1996 |
Schreibmayer W, Dessauer CW, Vorobiov D, Gilman AG, Lester HA, Davidson N, Dascal N. Inhibition of an inwardly rectifying K+ channel by G-protein alpha-subunits. Nature. 380: 624-7. PMID 8602262 DOI: 10.1038/380624A0 |
0.625 |
|
| 1996 |
Schreibmayer W, Dessauer CW, Vorobiov D, Gilman AG, Lester HA, Davidson N, Dascal N. Correction: Inhibition of an inwardly rectifying K+ channel by G-protein α-subunits Nature. 383: 103-103. DOI: 10.1038/383103C0 |
0.556 |
|
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