Year |
Citation |
Score |
2024 |
Kobeissi H, Jilberto J, Karakan MÇ, Gao X, DePalma SJ, Das SL, Quach L, Urquia J, Baker BM, Chen CS, Nordsletten D, Lejeune E. MicroBundleCompute: Automated segmentation, tracking, and analysis of subdomain deformation in cardiac microbundles. Plos One. 19: e0298863. PMID 38530829 DOI: 10.1371/journal.pone.0298863 |
0.801 |
|
2024 |
van Dover G, Javor J, Ewoldt JK, Zhernenkov M, Wąsik P, Freychet G, Lee J, Brown D, Chen CS, Bishop DJ. Structural maturation of myofilaments in engineered 3D cardiac microtissues characterized using small angle X-ray scattering. Physical Biology. PMID 38452380 DOI: 10.1088/1478-3975/ad310e |
0.783 |
|
2024 |
Feaster TK, Ewoldt JK, Avila A, Casciola M, Narkar A, Chen CS, Blinova K. Nonclinical evaluation of chronic cardiac contractility modulation on 3D human engineered cardiac tissues. Journal of Cardiovascular Electrophysiology. PMID 38433304 DOI: 10.1111/jce.16222 |
0.768 |
|
2024 |
Yordanov TE, Keyser MS, Enriquez Martinez MA, Esposito T, Tefft JB, Morris EK, Labzin LI, Stehbens SJ, Rowan AE, Hogan BM, Chen CS, Lauko J, Lagendijk AK. Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels. Apl Bioengineering. 8: 016108. PMID 38352162 DOI: 10.1063/5.0159330 |
0.769 |
|
2024 |
Karakan MÇ, Ewoldt JK, Segarra AJ, Sundaram S, Wang MC, White AE, Chen CS, Ekinci KL. Geometry and length control of 3D engineered heart tissues using direct laser writing. Lab On a Chip. PMID 38317604 DOI: 10.1039/d3lc00752a |
0.78 |
|
2023 |
Lee E, Chan SL, Lee Y, Polacheck WJ, Kwak S, Wen A, Nguyen DT, Kutys ML, Alimperti S, Kolarzyk AM, Kwak TJ, Eyckmans J, Bielenberg DR, Chen H, Chen CS. A 3D biomimetic model of lymphatics reveals cell-cell junction tightening and lymphedema via a cytokine-induced ROCK2/JAM-A complex. Proceedings of the National Academy of Sciences of the United States of America. 120: e2308941120. PMID 37782785 DOI: 10.1073/pnas.2308941120 |
0.805 |
|
2023 |
Griebel M, Vasan A, Chen C, Eyckmans J. Fibroblast clearance of damaged tissue following laser ablation in engineered microtissues. Apl Bioengineering. 7: 016112. PMID 36938481 DOI: 10.1063/5.0133478 |
0.78 |
|
2023 |
Moore J, Ewoldt J, Venturini G, Pereira AC, Padilha K, Lawton M, Lin W, Goel R, Luptak I, Perissi V, Seidman CE, Seidman J, Chin MT, Chen C, Emili A. Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation-Contraction Coupling. International Journal of Molecular Sciences. 24. PMID 36902152 DOI: 10.3390/ijms24054724 |
0.77 |
|
2023 |
Paul I, Bolzan D, Youssef A, Gagnon KA, Hook H, Karemore G, Oliphant MUJ, Lin W, Liu Q, Phanse S, White C, Padhorny D, Kotelnikov S, Chen CS, Hu P, et al. Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT. Nature Communications. 14: 688. PMID 36755019 DOI: 10.1038/s41467-023-36122-x |
0.664 |
|
2022 |
Das SL, Sutherland BP, Lejeune E, Eyckmans J, Chen CS. Mechanical response of cardiac microtissues to acute localized injury. American Journal of Physiology. Heart and Circulatory Physiology. 323: H738-H748. PMID 36053751 DOI: 10.1152/ajpheart.00305.2022 |
0.796 |
|
2022 |
Michas C, Karakan MÇ, Nautiyal P, Seidman JG, Seidman CE, Agarwal A, Ekinci K, Eyckmans J, White AE, Chen CS. Engineering a living cardiac pump on a chip using high-precision fabrication. Science Advances. 8: eabm3791. PMID 35452278 DOI: 10.1126/sciadv.abm3791 |
0.705 |
|
2021 |
Tefft JB, Bays JL, Lammers A, Kim S, Eyckmans J, Chen CS. Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature. American Journal of Physiology. Cell Physiology. PMID 34878922 DOI: 10.1152/ajpcell.00320.2021 |
0.787 |
|
2021 |
Zhang K, Cloonan PE, Sundaram S, Liu F, Das SL, Ewoldt JK, Bays JL, Tomp S, Toepfer CN, Marsiglia JDC, Gorham J, Reichart D, Eyckmans J, Seidman JG, Seidman CE, ... Chen CS, et al. Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization. Science Advances. 7: eabh3995. PMID 34652945 DOI: 10.1126/sciadv.abh3995 |
0.764 |
|
2021 |
Zhao B, Zhang K, Chen CS, Lejeune E. Sarc-Graph: Automated segmentation, tracking, and analysis of sarcomeres in hiPSC-derived cardiomyocytes. Plos Computational Biology. 17: e1009443. PMID 34613960 DOI: 10.1371/journal.pcbi.1009443 |
0.675 |
|
2021 |
Javor J, Ewoldt JK, Cloonan PE, Chopra A, Luu RJ, Freychet G, Zhernenkov M, Ludwig K, Seidman JG, Seidman CE, Chen CS, Bishop DJ. Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue. Microsystems & Nanoengineering. 7: 10. PMID 34567727 DOI: 10.1038/s41378-020-00234-x |
0.793 |
|
2021 |
Agarwal R, Paulo J, Toepfer CN, Ewoldt JK, Sundaram S, Chopra A, Zhang Q, Gorham J, DePalma S, Chen CS, Gygi S, Seidman CE, Seidman JG. Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation. Circulation Research. PMID 34405687 DOI: 10.1161/CIRCRESAHA.120.317076 |
0.782 |
|
2021 |
Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Fuchs SY, et al. SARS-CoV-2 disrupts proximal elements in the JAK-STAT pathway. Journal of Virology. JVI0086221. PMID 34260266 DOI: 10.1128/JVI.00862-21 |
0.775 |
|
2021 |
Das SL, Bose P, Lejeune E, Reich DH, Chen C, Eyckmans J. Extracellular Matrix Alignment Directs Provisional Matrix Assembly and Three Dimensional Fibrous Tissue Closure. Tissue Engineering. Part A. PMID 33979548 DOI: 10.1089/ten.tea.2020.0332 |
0.797 |
|
2021 |
Jayne RK, Karakan MÇ, Zhang K, Pierce N, Michas C, Bishop DJ, Chen CS, Ekinci KL, White AE. Direct laser writing for cardiac tissue engineering: a microfluidic heart on a chip with integrated transducers. Lab On a Chip. 21: 1724-1737. PMID 33949395 DOI: 10.1039/d0lc01078b |
0.797 |
|
2021 |
Tsang JM, Gritton HJ, Das SL, Weber TD, Chen CS, Han X, Mertz J. Fast, multiplane line-scan confocal microscopy using axially distributed slits. Biomedical Optics Express. 12: 1339-1350. PMID 33796357 DOI: 10.1364/BOE.417286 |
0.768 |
|
2021 |
Song J, Michas C, Chen CS, White AE, Grinstaff MW. Controlled Cell Alignment Using Two-Photon Direct Laser Writing-Patterned Hydrogels in 2D and 3D. Macromolecular Bioscience. e2100051. PMID 33738917 DOI: 10.1002/mabi.202100051 |
0.734 |
|
2021 |
Kostecki GM, Shi Y, Chen CS, Reich DH, Entcheva E, Tung L. Optogenetic current in myofibroblasts acutely alters electrophysiology and conduction of co-cultured cardiomyocytes. Scientific Reports. 11: 4430. PMID 33627695 DOI: 10.1038/s41598-021-83398-4 |
0.517 |
|
2021 |
Ward TL, Tai W, Morton SU, Impens F, VanDamme P, Van Haver D, Timmerman E, Venturini G, Zhang K, Jang MY, Willcox JA, Haghighi A, Gelb BD, Chung WK, Goldmuntz E, ... ... Chen CS, et al. Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency. Circulation Research. PMID 33557580 DOI: 10.1161/CIRCRESAHA.120.316966 |
0.7 |
|
2021 |
Tefft JB, Chen CS, Eyckmans J. Reconstituting the dynamics of endothelial cells and fibroblasts in wound closure. Apl Bioengineering. 5: 016102. PMID 33511324 DOI: 10.1063/5.0028651 |
0.778 |
|
2020 |
Chen AX, Chhabra A, Song HG, Fleming HE, Chen CS, Bhatia SN. Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers. Advanced Functional Materials. 30. PMID 33776613 DOI: 10.1002/Adfm.201910442 |
0.412 |
|
2020 |
Song HG, Lammers A, Sundaram S, Rubio L, Chen AX, Li L, Eyckmans J, Bhatia SN, Chen CS. Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues. Advanced Functional Materials. 30. PMID 33613149 DOI: 10.1002/Adfm.202003777 |
0.821 |
|
2020 |
Chen D, Smith LR, Khandekar G, Patel P, Yu CK, Zhang K, Chen CS, Han L, Wells RG. Distinct effects of different matrix proteoglycans on collagen fibrillogenesis and cell-mediated collagen reorganization. Scientific Reports. 10: 19065. PMID 33149218 DOI: 10.1038/s41598-020-76107-0 |
0.793 |
|
2020 |
Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Kapell S, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, et al. SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway. Biorxiv : the Preprint Server For Biology. PMID 33140044 DOI: 10.1101/2020.10.27.358259 |
0.771 |
|
2020 |
Pua CJ, Tham N, Chin CW, Walsh R, Khor CC, Toepfer CN, Repetti GG, Garfinkel AC, Ewoldt JF, Cloonan P, Chen CS, Lim SQ, Cai J, Loo LY, Kong SC, et al. Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in and that Are Common in Chinese Patients. Circulation. Genomic and Precision Medicine. PMID 32815737 DOI: 10.1161/CIRCGEN.119.002823 |
0.738 |
|
2020 |
Kutys ML, Polacheck WJ, Welch MK, Gagnon KA, Koorman T, Kim S, Li L, McClatchey AI, Chen CS. Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform. Nature Communications. 11: 3377. PMID 32632100 DOI: 10.1038/S41467-020-17102-X |
0.697 |
|
2020 |
Song D, Dong L, Gupta M, Li L, Klaas O, Loghin A, Beall M, Chen C, Oberai AA. Recovery of Tractions Exerted by Singe Cells in 3D Nonlinear Matrices. Journal of Biomechanical Engineering. PMID 32320015 DOI: 10.1115/1.4046974 |
0.354 |
|
2020 |
Shroff SN, Das SL, Tseng HA, Noueihed J, Fernandez F, White JA, Chen CS, Han X. Voltage Imaging of Cardiac Cells and Tissue Using the Genetically Encoded Voltage Sensor Archon1. Iscience. 23: 100974. PMID 32299055 DOI: 10.1016/J.Isci.2020.100974 |
0.795 |
|
2020 |
Park JS, Burckhardt CJ, Lazcano R, Solis LM, Isogai T, Li L, Chen CS, Gao B, Minna JD, Bachoo R, DeBerardinis RJ, Danuser G. Mechanical regulation of glycolysis via cytoskeleton architecture. Nature. PMID 32051585 DOI: 10.1038/S41586-020-1998-1 |
0.406 |
|
2020 |
Toepfer CN, Garfinkel AC, Venturini G, Wakimoto H, Repetti G, Alamo L, Sharma A, Agarwal R, Ewoldt JF, Cloonan P, Letendre J, Lun M, Olivotto I, Colan S, Ashley E, ... ... Chen CS, et al. Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy. Circulation. PMID 31983222 DOI: 10.1161/Circulationaha.119.042339 |
0.776 |
|
2019 |
Bose P, Eyckmans J, Nguyen TD, Chen CS, Reich DH. Effects of Geometry on the Mechanics and Alignment of Three-Dimensional Engineered Microtissues. Acs Biomaterials Science & Engineering. 5: 3843-3855. PMID 33438424 DOI: 10.1021/Acsbiomaterials.8B01183 |
0.622 |
|
2019 |
Song J, Michas C, Chen CS, White AE, Grinstaff MW. From Simple to Architecturally Complex Hydrogel Scaffolds for Cell and Tissue Engineering Applications: Opportunities Presented by Two-Photon Polymerization. Advanced Healthcare Materials. e1901217. PMID 31746140 DOI: 10.1002/Adhm.201901217 |
0.731 |
|
2019 |
Nguyen DT, Lee E, Alimperti S, Norgard RJ, Wong A, Lee JJ, Eyckmans J, Stanger BZ, Chen CS. A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling. Science Advances. 5: eaav6789. PMID 31489365 DOI: 10.1126/Sciadv.Aav6789 |
0.794 |
|
2019 |
Du Y, Khandekar G, Llewellyn J, Polacheck W, Chen CS, Wells RG. A Bile Duct-on-a-Chip with Organ-Level Functions. Hepatology (Baltimore, Md.). PMID 31465556 DOI: 10.1002/Hep.30918 |
0.311 |
|
2019 |
Cardenas-Diaz FL, Osorio-Quintero C, Diaz-Miranda MA, Kishore S, Leavens K, Jobaliya C, Stanescu D, Ortiz-Gonzalez X, Yoon C, Chen CS, Haliyur R, Brissova M, Powers AC, French DL, Gadue P. Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A. Cell Stem Cell. 25: 273-289.e5. PMID 31374199 DOI: 10.1016/J.Stem.2019.07.007 |
0.78 |
|
2019 |
Li S, Chopra A, Keung W, Chan C, Costa KD, Kong CW, Hajjar RJ, Chen C, Li R. Sarco/Endoplasmic Reticulum Ca-ATPase is a more effective calcium remover than Sodium-Calcium Exchanger in human embryonic stem cell-derived cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31347915 DOI: 10.1152/Ajpheart.00540.2018 |
0.727 |
|
2019 |
Yoon C, Choi C, Stapleton S, Mirabella T, Howes C, Dong L, King J, Yang J, Oberai A, Eyckmans J, Chen CS. Myosin IIA-mediated forces regulate multicellular integrity during vascular sprouting. Molecular Biology of the Cell. mbcE19020076. PMID 31318321 DOI: 10.1091/Mbc.E19-02-0076 |
0.833 |
|
2019 |
Chow MZ, Sadrian SN, Keung W, Geng L, Ren L, Kong CW, Wong AO, Hulot JS, Chen CS, Costa KD, Hajjar RJ, Li RA. Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues. Scientific Reports. 9: 7502. PMID 31097748 DOI: 10.1038/S41598-019-42953-W |
0.39 |
|
2019 |
Polacheck WJ, Kutys ML, Tefft JB, Chen CS. Microfabricated blood vessels for modeling the vascular transport barrier. Nature Protocols. PMID 30953042 DOI: 10.1038/S41596-019-0144-8 |
0.775 |
|
2019 |
Cheng D, Jayne RK, Tamborini A, Eyckmans J, White AE, Chen CS. Studies of 3D directed cell migration enabled by direct laser writing of curved wave topography. Biofabrication. PMID 30721899 DOI: 10.1088/1758-5090/Ab047F |
0.747 |
|
2019 |
Toepfer CN, Sharma A, Cicconet M, Garfinkel AC, Mücke M, Neyazi M, Willcox JA, Agarwal R, Schmid M, Rao J, Ewoldt JK, Pourquié O, Chopra A, Chen C, Seidman JG, et al. SarcTrack: An Adaptable Software Tool for Efficient Large-Scale Analysis of Sarcomere Function in hiPSC-Cardiomyocytes. Circulation Research. PMID 30700234 DOI: 10.1161/Circresaha.118.314505 |
0.798 |
|
2019 |
Zhang K, Tomp S, Ewoldt JK, Toepfer CN, Chopra A, Seidman CE, Seidman JG, Chen CS. Abstract 482: Modeling PKP2 Mutation Associated Arrhythmogenic Cardiomyopathy With CRISPR-edited iPSC-derived Cardiomyocytes in Engineered Cardiac Tissues Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.482 |
0.781 |
|
2019 |
Das S, Shroff S, Tseng H, Chopra A, Han X, Chen C. Abstract 462: High Speed Imaging of Single Cardiomyocyte Action Potentials Using a Far-red Genetically Encoded Voltage Sensor Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.462 |
0.755 |
|
2019 |
Michas C, Nautiyal P, Agarwal A, White AE, Chen CS. Abstract 417: A 3D iPSC-derived Scaffold-Assisted Microfluidic Model of Ventricular Ejection Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.417 |
0.701 |
|
2019 |
Toepfer C, Sharma A, Garfinkel A, Cicconet M, Agarwal R, Chopra A, Chen C, Seidman J, Seidman C. Abstract 341: Efficient Large-scale Sarcomere Tracking (sarctrack) to Assess HCM Variants in iPSC-CMs Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.341 |
0.699 |
|
2019 |
Kai F, Ou G, Long A, Guo W, Tourdot R, Radhakrishnan R, Chen C, Dumont S, Weaver VM. Abstract 1028: Extracellular matrix dimensionality reduces cellular cortical tension to stimulate pro-survival signaling in mammary epithelial cells Cancer Research. 79: 1028-1028. DOI: 10.1158/1538-7445.Am2019-1028 |
0.394 |
|
2018 |
Wang WY, Pearson AT, Kutys ML, Choi CK, Wozniak MA, Baker BM, Chen CS. Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration. Apl Bioengineering. 2: 046107. PMID 31069329 DOI: 10.1063/1.5052239 |
0.331 |
|
2018 |
Hassell BA, Goyal G, Lee E, Sontheimer-Phelps A, Levy O, Chen CS, Ingber DE. Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell Reports. 23: 3698. PMID 29925009 DOI: 10.1016/j.celrep.2018.06.028 |
0.766 |
|
2018 |
Benhamouche-Trouillet S, O'Loughlin E, Liu CH, Polacheck W, Fitamant J, McKee M, El-Bardeesy N, Chen CS, McClatchey AI. Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis. Development (Cambridge, England). 145. PMID 29712669 DOI: 10.1242/Dev.162123 |
0.307 |
|
2018 |
Longchamp A, Mirabella T, Arduini A, MacArthur MR, Das A, Treviño-Villarreal JH, Hine C, Ben-Sahra I, Knudsen NH, Brace LE, Reynolds J, Mejia P, Tao M, Sharma G, Wang R, ... ... Chen CS, et al. Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and HS Production. Cell. 173: 117-129.e14. PMID 29570992 DOI: 10.1016/J.Cell.2018.03.001 |
0.303 |
|
2018 |
Song HG, Rumma RT, Ozaki CK, Edelman ER, Chen CS. Vascular Tissue Engineering: Progress, Challenges, and Clinical Promise. Cell Stem Cell. 22: 340-354. PMID 29499152 DOI: 10.1016/J.Stem.2018.02.009 |
0.352 |
|
2018 |
von Erlach TC, Bertazzo S, Wozniak MA, Horejs CM, Maynard SA, Attwood S, Robinson BK, Autefage H, Kallepitis C, Del Río Hernández A, Chen CS, Goldoni S, Stevens MM. Cell-geometry-dependent changes in plasma membrane order direct stem cell signalling and fate. Nature Materials. PMID 29434303 DOI: 10.1038/S41563-017-0014-0 |
0.393 |
|
2018 |
Chopra A, Kutys ML, Zhang K, Polacheck WJ, Sheng CC, Luu RJ, Eyckmans J, Hinson JT, Seidman JG, Seidman CE, Chen CS. Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions. Developmental Cell. 44: 87-96.e5. PMID 29316444 DOI: 10.1016/J.Devcel.2017.12.012 |
0.792 |
|
2018 |
Bose P, Huang CY, Eyckmans J, Chen CS, Reich DH. Fabrication and Mechanical Properties Measurements of 3D Microtissues for the Study of Cell-Matrix Interactions. Methods in Molecular Biology (Clifton, N.J.). 1722: 303-328. PMID 29264812 DOI: 10.1007/978-1-4939-7553-2_18 |
0.334 |
|
2018 |
Bose P, Huang CY, Eyckmans J, Chen CS, Reich DH. Fabrication and Mechanical Properties Measurements of 3D Microtissues for the Study of Cell-Matrix Interactions. Methods in Molecular Biology (Clifton, N.J.). 1722: 303-328. PMID 29264812 DOI: 10.1007/978-1-4939-7553-2_18 |
0.667 |
|
2017 |
Mirabella T, MacArthur JW, Cheng D, Ozaki CK, Woo YJ, Yang M, Chen CS. 3D-printed vascular networks direct therapeutic angiogenesis in ischaemia. Nature Biomedical Engineering. 1. PMID 29515935 DOI: 10.1038/S41551-017-0083 |
0.333 |
|
2017 |
Li L, Eyckmans J, Chen CS. Designer biomaterials for mechanobiology. Nature Materials. 16: 1164-1168. PMID 29170549 DOI: 10.1038/Nmat5049 |
0.335 |
|
2017 |
Polacheck WJ, Kutys ML, Yang J, Eyckmans J, Wu Y, Vasavada H, Hirschi KK, Chen CS. A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Nature. PMID 29160307 DOI: 10.1038/Nature24998 |
0.336 |
|
2017 |
Chen CS. Forces as regulators of cell adhesions. Nature Reviews. Molecular Cell Biology. PMID 29093558 DOI: 10.1038/Nrm.2017.112 |
0.353 |
|
2017 |
Hassell BA, Goyal G, Lee E, Sontheimer-Phelps A, Levy O, Chen CS, Ingber DE. Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell Reports. 21: 508-516. PMID 29020635 DOI: 10.1016/J.Celrep.2017.09.043 |
0.785 |
|
2017 |
Trappmann B, Baker BM, Polacheck WJ, Choi CK, Burdick JA, Chen CS. Matrix degradability controls multicellularity of 3D cell migration. Nature Communications. 8: 371. PMID 28851858 DOI: 10.1038/S41467-017-00418-6 |
0.436 |
|
2017 |
Alimperti S, Mirabella T, Bajaj V, Polacheck W, Pirone DM, Duffield J, Eyckmans J, Assoian RK, Chen CS. Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N-cadherin balance in mural cell-endothelial cell-regulated barrier function. Proceedings of the National Academy of Sciences of the United States of America. PMID 28765370 DOI: 10.1073/Pnas.1618333114 |
0.412 |
|
2017 |
Stevens KR, Scull MA, Ramanan V, Fortin CL, Chaturvedi RR, Knouse KA, Xiao JW, Fung C, Mirabella T, Chen AX, McCue MG, Yang MT, Fleming HE, Chung K, de Jong YP, ... Chen CS, et al. In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease. Science Translational Medicine. 9. PMID 28724577 DOI: 10.1126/Scitranslmed.Aah5505 |
0.794 |
|
2017 |
Dang LTH, Aburatani T, Marsh GA, Johnson BG, Alimperti S, Yoon CJ, Huang A, Szak S, Nakagawa N, Gomez I, Ren S, Read SK, Sparages C, Aplin AC, Nicosia RF, ... Chen C, et al. Hyperactive FOXO1 results in lack of tip stalk identity and deficient microvascular regeneration during kidney injury. Biomaterials. 141: 314-329. PMID 28711779 DOI: 10.1016/J.Biomaterials.2017.07.010 |
0.81 |
|
2017 |
Bendell AC, Williamson EK, Chen CS, Burkhardt JK, Hammer DA. The Arp2/3 complex binding protein HS1 is required for efficient dendritic cell random migration and force generation. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 28678266 DOI: 10.1039/C7Ib00070G |
0.324 |
|
2017 |
Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Burke MA, Zhang K, Musunuru K, Gerszten RE, Wu SM, ... Chen CS, et al. Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. Cell Reports. 19: 2410. PMID 28614725 DOI: 10.1016/j.celrep.2017.05.038 |
0.765 |
|
2017 |
Cao X, Ban E, Baker BM, Lin Y, Burdick JA, Chen CS, Shenoy VB. Multiscale model predicts increasing focal adhesion size with decreasing stiffness in fibrous matrices. Proceedings of the National Academy of Sciences of the United States of America. PMID 28468803 DOI: 10.1073/Pnas.1620486114 |
0.363 |
|
2017 |
Nguyen DT, Gao L, Wong A, Chen CS. Cdc42 regulates branching in angiogenic sprouting in vitro. Microcirculation (New York, N.Y. : 1994). PMID 28376260 DOI: 10.1111/Micc.12372 |
0.722 |
|
2017 |
Shaya O, Binshtok U, Hersch M, Rivkin D, Weinreb S, Amir-Zilberstein L, Khamaisi B, Oppenheim O, Desai RA, Goodyear RJ, Richardson GP, Chen CS, Sprinzak D. Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning. Developmental Cell. 40: 505-511.e6. PMID 28292428 DOI: 10.1016/J.Devcel.2017.02.009 |
0.639 |
|
2017 |
Choi D, Park E, Jung E, Seong YJ, Yoo J, Lee E, Hong M, Lee S, Ishida H, Burford J, Peti-Peterdi J, Adams RH, Srikanth S, Gwack Y, Chen CS, et al. Laminar flow downregulates Notch activity to promote lymphatic sprouting. The Journal of Clinical Investigation. PMID 28263185 DOI: 10.1172/Jci87442 |
0.791 |
|
2016 |
Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, et al. Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. Cell Reports. 17: 3292-3304. PMID 28009297 DOI: 10.1016/J.Celrep.2016.11.066 |
0.783 |
|
2016 |
Eyckmans J, Chen CS. 3D culture models of tissues under tension. Journal of Cell Science. PMID 27909243 DOI: 10.1242/Jcs.198630 |
0.419 |
|
2016 |
Heo SJ, Driscoll TP, Thorpe SD, Nerurkar NL, Baker BM, Yang MT, Chen CS, Lee DA, Mauck RL. Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity. Elife. 5. PMID 27901466 DOI: 10.7554/Elife.18207 |
0.535 |
|
2016 |
Keung W, Ren L, Sen Li, Wong AO, Chopra A, Kong CW, Tomaselli GF, Chen CS, Li RA. Non-cell autonomous cues for enhanced functionality of human embryonic stem cell-derived cardiomyocytes via maturation of sarcolemmal and mitochondrial KATP channels. Scientific Reports. 6: 34154. PMID 27677332 DOI: 10.1038/Srep34154 |
0.745 |
|
2016 |
Liu AS, Wang H, Copeland CR, Chen CS, Shenoy VB, Reich DH. Matrix viscoplasticity and its shielding by active mechanics in microtissue models: experiments and mathematical modeling. Scientific Reports. 6: 33919. PMID 27671239 DOI: 10.1038/Srep33919 |
0.645 |
|
2016 |
Chen CS. 3D Biomimetic Cultures: The Next Platform for Cell Biology. Trends in Cell Biology. PMID 27637342 DOI: 10.1016/J.Tcb.2016.08.008 |
0.339 |
|
2016 |
Lee E, Song HG, Chen CS. Biomimetic on-a-chip platforms for studying cancer metastasis. Current Opinion in Chemical Engineering. 11: 20-27. PMID 27570735 DOI: 10.1016/J.Coche.2015.12.001 |
0.774 |
|
2016 |
Foolen J, Shiu JY, Mitsi M, Zhang Y, Chen CS, Vogel V. Full-Length Fibronectin Drives Fibroblast Accumulation at the Surface of Collagen Microtissues during Cell-Induced Tissue Morphogenesis. Plos One. 11: e0160369. PMID 27564551 DOI: 10.1371/Journal.Pone.0160369 |
0.429 |
|
2016 |
Kutys ML, Chen CS. Forces and mechanotransduction in 3D vascular biology. Current Opinion in Cell Biology. 42: 73-79. PMID 27209346 DOI: 10.1016/J.Ceb.2016.04.011 |
0.395 |
|
2016 |
Polacheck WJ, Chen CS. Measuring cell-generated forces: a guide to the available tools. Nature Methods. 13: 415-423. PMID 27123817 DOI: 10.1038/Nmeth.3834 |
0.362 |
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2016 |
Sakar MS, Eyckmans J, Pieters R, Eberli D, Nelson BJ, Chen CS. Cellular forces and matrix assembly coordinate fibrous tissue repair. Nature Communications. 7: 11036. PMID 26980715 DOI: 10.1038/Ncomms11036 |
0.418 |
|
2016 |
Mui KL, Chen CS, Assoian RK. The mechanical regulation of integrin-cadherin crosstalk organizes cells, signaling and forces. Journal of Cell Science. PMID 26919980 DOI: 10.1242/Jcs.183699 |
0.395 |
|
2016 |
Heo S, Driscoll TP, Thorpe SD, Nerurkar NL, Baker BM, Yang MT, Chen CS, Lee DA, Mauck RL. Author response: Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity Elife. DOI: 10.7554/Elife.18207.028 |
0.317 |
|
2016 |
Lee E, Song HHG, Chen CS. Biomimetic on-a-chip platforms for studying cancer metastasis Current Opinion in Chemical Engineering. 11: 20-27. DOI: 10.1016/j.coche.2015.12.001 |
0.754 |
|
2015 |
Baker BM, Trappmann B, Wang WY, Sakar MS, Kim IL, Shenoy VB, Burdick JA, Chen CS. Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments. Nature Materials. PMID 26461445 DOI: 10.1038/Nmat4444 |
0.427 |
|
2015 |
Wu HC, Chen TC, Lai NC, Yang CM, Wu JH, Chen YC, Lee JF, Chen CS. Synthesis of sub-nanosized Pt particles on mesoporous SBA-15 material and its application to the CO oxidation reaction. Nanoscale. PMID 26403094 DOI: 10.1039/c5nr04943a |
0.327 |
|
2015 |
Hinson JT, Chopra A, Nafissi N, Polacheck WJ, Benson CC, Swist S, Gorham J, Yang L, Schafer S, Sheng CC, Haghighi A, Homsy J, Hubner N, Church G, Cook SA, ... ... Chen CS, et al. HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy. Science (New York, N.Y.). 349: 982-6. PMID 26315439 DOI: 10.1126/Science.Aaa5458 |
0.741 |
|
2015 |
Henry SJ, Chen CS, Crocker JC, Hammer DA. Protrusive and Contractile Forces of Spreading Human Neutrophils. Biophysical Journal. 109: 699-709. PMID 26287622 DOI: 10.1016/J.Bpj.2015.05.041 |
0.342 |
|
2015 |
Cohen DM, Won KJ, Nguyen N, Lazar MA, Chen C, Steger D. ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis. Elife. 4. PMID 26111340 DOI: 10.7554/Elife.06821 |
0.316 |
|
2015 |
Stevens KR, Miller JS, Blakely BL, Chen CS, Bhatia SN. Degradable hydrogels derived from PEG-diacrylamide for hepatic tissue engineering. Journal of Biomedical Materials Research. Part A. PMID 25851120 DOI: 10.1002/Jbm.A.35478 |
0.792 |
|
2015 |
Poon E, Keung W, Liang Y, Ramalingam R, Yan B, Zhang S, Chopra A, Moore J, Herren A, Lieu DK, Wong HS, Weng Z, Wong OT, Lam YW, Tomaselli GF, ... Chen C, et al. Proteomic Analysis of Human Pluripotent Stem Cell-Derived, Fetal, and Adult Ventricular Cardiomyocytes Reveals Pathways Crucial for Cardiac Metabolism and Maturation. Circulation. Cardiovascular Genetics. 8: 427-36. PMID 25759434 DOI: 10.1161/Circgenetics.114.000918 |
0.733 |
|
2015 |
Mui KL, Bae YH, Gao L, Liu SL, Xu T, Radice GL, Chen CS, Assoian RK. N-Cadherin Induction by ECM Stiffness and FAK Overrides the Spreading Requirement for Proliferation of Vascular Smooth Muscle Cells. Cell Reports. PMID 25753414 DOI: 10.1016/J.Celrep.2015.02.023 |
0.406 |
|
2015 |
Elliott H, Fischer RS, Myers KA, Desai RA, Gao L, Chen CS, Adelstein RS, Waterman CM, Danuser G. Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature. Nature Cell Biology. 17: 137-47. PMID 25621949 DOI: 10.1038/Ncb3092 |
0.652 |
|
2015 |
Rana MK, Srivastava J, Yang M, Chen CS, Barber DL. Hypoxia increases the abundance but not the assembly of extracellular fibronectin during epithelial cell transdifferentiation. Journal of Cell Science. 128: 1083-9. PMID 25616899 DOI: 10.1242/Jcs.155036 |
0.58 |
|
2015 |
Byron A, Askari JA, Humphries JD, Jacquemet G, Koper EJ, Warwood S, Choi CK, Stroud MJ, Chen CS, Knight D, Humphries MJ. A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting. Nature Communications. 6: 6135. PMID 25609142 DOI: 10.1038/Ncomms7135 |
0.339 |
|
2015 |
Galie PA, van Oosten A, Chen CS, Janmey PA. Application of multiple levels of fluid shear stress to endothelial cells plated on polyacrylamide gels. Lab On a Chip. 15: 1205-12. PMID 25573790 DOI: 10.1039/C4Lc01236D |
0.558 |
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2015 |
Ronan W, McMeeking RM, Chen CS, McGarry JP, Deshpande VS. Cooperative contractility: the role of stress fibres in the regulation of cell-cell junctions. Journal of Biomechanics. 48: 520-8. PMID 25553672 DOI: 10.1016/J.Jbiomech.2014.11.025 |
0.418 |
|
2015 |
Chen G, Li S, Karakikes I, Ren L, Chow MZ, Chopra A, Keung W, Yan B, Chan CW, Costa KD, Kong CW, Hajjar RJ, Chen CS, Li RA. Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs. Circulation. Arrhythmia and Electrophysiology. 8: 193-202. PMID 25504561 DOI: 10.1161/Circep.114.002049 |
0.748 |
|
2015 |
Chaturvedi RR, Stevens KR, Solorzano RD, Schwartz RE, Eyckmans J, Baranski JD, Stapleton SC, Bhatia SN, Chen CS. Patterning vascular networks in vivo for tissue engineering applications. Tissue Engineering. Part C, Methods. 21: 509-17. PMID 25390971 DOI: 10.1089/Ten.Tec.2014.0258 |
0.805 |
|
2015 |
Galie PA, Byfield FJ, Chen CS, Kresh JY, Janmey PA. Mechanically stimulated contraction of engineered cardiac constructs using a microcantilever. Ieee Transactions On Bio-Medical Engineering. 62: 438-42. PMID 25248171 DOI: 10.1109/Tbme.2014.2357778 |
0.722 |
|
2015 |
Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW. Correction: Design and formulation of functional pluripotent stem cell-derived cardiac microtissues (Proceedings of the National Academy of Sciences (2013) 110, (E4698-E4707) DOI:10.1073/pnas.1311120110) Proceedings of the National Academy of Sciences of the United States of America. 112: E3151. DOI: 10.1073/Pnas.1311120110). |
0.516 |
|
2015 |
Henry SJ, Chen CS, Crocker JC, Hammer DA. Dynamic Traction Forces of Human Neutrophil Adhesion Biophysical Journal. 108: 495a. DOI: 10.1016/J.Bpj.2014.11.2706 |
0.386 |
|
2014 |
Breckenridge MT, Desai RA, Yang MT, Fu J, Chen CS. Substrates with engineered step changes in rigidity induce traction force polarity and durotaxis. Cellular and Molecular Bioengineering. 7: 26-34. PMID 27721906 DOI: 10.1007/S12195-013-0307-6 |
0.74 |
|
2014 |
Wang H, Abhilash AS, Chen CS, Wells RG, Shenoy VB. Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibers. Biophysical Journal. 107: 2592-603. PMID 25468338 DOI: 10.1016/J.Bpj.2014.09.044 |
0.329 |
|
2014 |
Abhilash AS, Baker BM, Trappmann B, Chen CS, Shenoy VB. Remodeling of fibrous extracellular matrices by contractile cells: predictions from discrete fiber network simulations. Biophysical Journal. 107: 1829-40. PMID 25418164 DOI: 10.1016/J.Bpj.2014.08.029 |
0.383 |
|
2014 |
Blakely BL, Dumelin CE, Trappmann B, McGregor LM, Choi CK, Anthony PC, Duesterberg VK, Baker BM, Block SM, Liu DR, Chen CS. A DNA-based molecular probe for optically reporting cellular traction forces. Nature Methods. 11: 1229-32. PMID 25306545 DOI: 10.1038/Nmeth.3145 |
0.789 |
|
2014 |
Bellas E, Chen CS. Forms, forces, and stem cell fate. Current Opinion in Cell Biology. 31: 92-7. PMID 25269668 DOI: 10.1016/J.Ceb.2014.09.006 |
0.465 |
|
2014 |
Atluri P, Miller JS, Emery RJ, Hung G, Trubelja A, Cohen JE, Lloyd K, Han J, Gaffey AC, MacArthur JW, Chen CS, Woo YJ. Tissue-engineered, hydrogel-based endothelial progenitor cell therapy robustly revascularizes ischemic myocardium and preserves ventricular function. The Journal of Thoracic and Cardiovascular Surgery. 148: 1090-7; discussion 1. PMID 25129603 DOI: 10.1016/J.Jtcvs.2014.06.038 |
0.44 |
|
2014 |
Moreno V, Gonzalo P, Gómez-Escudero J, Pollán Á, Acín-Pérez R, Breckenridge M, Yáñez-Mó M, Barreiro O, Orsenigo F, Kadomatsu K, Chen CS, Enríquez JA, Dejana E, Sánchez-Madrid F, Arroyo AG. An EMMPRIN-γ-catenin-Nm23 complex drives ATP production and actomyosin contractility at endothelial junctions. Journal of Cell Science. 127: 3768-81. PMID 24994937 DOI: 10.1242/Jcs.149518 |
0.39 |
|
2014 |
Eyckmans J, Chen CS. Stem cell differentiation: sticky mechanical memory. Nature Materials. 13: 542-3. PMID 24845990 DOI: 10.1038/Nmat3989 |
0.345 |
|
2014 |
Galie PA, Nguyen DH, Choi CK, Cohen DM, Janmey PA, Chen CS. Fluid shear stress threshold regulates angiogenic sprouting. Proceedings of the National Academy of Sciences of the United States of America. 111: 7968-73. PMID 24843171 DOI: 10.1073/Pnas.1310842111 |
0.766 |
|
2014 |
Zhao R, Boudou T, Wang WG, Chen CS, Reich DH. Magnetic approaches to study collective three-dimensional cell mechanics in long-term cultures (invited). Journal of Applied Physics. 115: 172616. PMID 24803684 DOI: 10.1063/1.4870918 |
0.735 |
|
2014 |
Stapleton SC, Chopra A, Chen CS. Force measurement tools to explore cadherin mechanotransduction. Cell Communication & Adhesion. 21: 193-205. PMID 24754475 DOI: 10.3109/15419061.2014.905929 |
0.825 |
|
2014 |
Choi CK, Chen CS. Jostling for position in angiogenic sprouts: continuous rearrangement of cells explained by differential adhesion dynamics. The Embo Journal. 33: 1089-90. PMID 24711516 DOI: 10.1002/Embj.201488452 |
0.441 |
|
2014 |
Zhao R, Chen CS, Reich DH. Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening. Biomaterials. 35: 5056-64. PMID 24630092 DOI: 10.1016/J.Biomaterials.2014.02.020 |
0.735 |
|
2014 |
Ramade A, Legant WR, Picart C, Chen CS, Boudou T. Microfabrication of a platform to measure and manipulate the mechanics of engineered microtissues. Methods in Cell Biology. 121: 191-211. PMID 24560511 DOI: 10.1016/B978-0-12-800281-0.00013-0 |
0.703 |
|
2014 |
van Spreeuwel AC, Bax NA, Bastiaens AJ, Foolen J, Loerakker S, Borochin M, van der Schaft DW, Chen CS, Baaijens FP, Bouten CV. The influence of matrix (an)isotropy on cardiomyocyte contraction in engineered cardiac microtissues. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 422-9. PMID 24549279 DOI: 10.1039/C3Ib40219C |
0.371 |
|
2014 |
Desai RA, Rodriguez NM, Chen CS. "Stamp-off" to micropattern sparse, multicomponent features. Methods in Cell Biology. 119: 3-16. PMID 24439276 DOI: 10.1016/B978-0-12-416742-1.00001-9 |
0.749 |
|
2014 |
Thompson SA, Blazeski A, Copeland CR, Cohen DM, Chen CS, Reich DM, Tung L. Acute slowing of cardiac conduction in response to myofibroblast coupling to cardiomyocytes through N-cadherin. Journal of Molecular and Cellular Cardiology. 68: 29-37. PMID 24412534 DOI: 10.1016/J.Yjmcc.2013.12.025 |
0.357 |
|
2014 |
Rodriguez NM, Desai RA, Trappmann B, Baker BM, Chen CS. Micropatterned multicolor dynamically adhesive substrates to control cell adhesion and multicellular organization. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 1327-35. PMID 24401172 DOI: 10.1021/La404037S |
0.76 |
|
2014 |
Li F, Xu T, Nguyen DH, Huang X, Chen CS, Zhou C. Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy. Journal of Biomedical Optics. 19: 16006. PMID 24395588 DOI: 10.1117/1.Jbo.19.1.016006 |
0.716 |
|
2014 |
Chopra A, Murray ME, Byfield FJ, Mendez MG, Halleluyan R, Restle DJ, Raz-Ben Aroush D, Galie PA, Pogoda K, Bucki R, Marcinkiewicz C, Prestwich GD, Zarembinski TI, Chen CS, Puré E, et al. Augmentation of integrin-mediated mechanotransduction by hyaluronic acid. Biomaterials. 35: 71-82. PMID 24120037 DOI: 10.1016/J.Biomaterials.2013.09.066 |
0.825 |
|
2014 |
Stevens K, Ungrin M, Schwartz R, Ng S, Carvalho B, Christine K, Chaturvedi R, Li C, Zandstra P, Chen C, Bhatia S. Erratum: InVERT molding for scalable control of tissue microarchitecture Nature Communications. 5. DOI: 10.1038/Ncomms4148 |
0.761 |
|
2014 |
Shenoy VB, Wang H, Svoronos AA, Boudou T, Morgan JR, Chen CS. Necking and Failure of Constrained Contractile 3D Microtissues Induced by Cell Derived Tension Biophysical Journal. 106: 614a-615a. DOI: 10.1016/J.Bpj.2013.11.3401 |
0.365 |
|
2014 |
Breckenridge MT, Desai RA, Yang MT, Fu J, Chen CS. Substrates with engineered step changes in rigidity induce traction force polarity and durotaxis Cellular and Molecular Bioengineering. 7: 26-34. DOI: 10.1007/s12195-013-0307-6 |
0.65 |
|
2013 |
Vunjak-Novakovic G, Bhatia S, Chen C, Hirschi K. HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease. Stem Cell Research & Therapy. 4: S8. PMID 24565063 DOI: 10.1186/Scrt369 |
0.338 |
|
2013 |
Wang H, Svoronos AA, Boudou T, Sakar MS, Schell JY, Morgan JR, Chen CS, Shenoy VB. Necking and failure of constrained 3D microtissues induced by cellular tension. Proceedings of the National Academy of Sciences of the United States of America. 110: 20923-8. PMID 24324149 DOI: 10.1073/Pnas.1313662110 |
0.353 |
|
2013 |
Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW. Design and formulation of functional pluripotent stem cell-derived cardiac microtissues. Proceedings of the National Academy of Sciences of the United States of America. 110: E4698-707. PMID 24255110 DOI: 10.1073/Pnas.1311120110 |
0.584 |
|
2013 |
He J, Kelly TN, Zhao Q, Li H, Huang J, Wang L, Jaquish CE, Sung YJ, Shimmin LC, Lu F, Mu J, Hu D, Ji X, Shen C, Guo D, ... ... Chen CS, et al. Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese. Circulation. Cardiovascular Genetics. 6: 598-607. PMID 24165912 DOI: 10.1161/Circgenetics.113.000307 |
0.356 |
|
2013 |
Desai RA, Gopal SB, Chen S, Chen CS. Contact inhibition of locomotion probabilities drive solitary versus collective cell migration. Journal of the Royal Society, Interface / the Royal Society. 10: 20130717. PMID 24047876 DOI: 10.1098/Rsif.2013.0717 |
0.65 |
|
2013 |
Wozniak MA, Baker BM, Chen CS, Wilson KL. The emerin-binding transcription factor Lmo7 is regulated by association with p130Cas at focal adhesions. Peerj. 1: e134. PMID 24010014 DOI: 10.7717/Peerj.134 |
0.336 |
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2013 |
Cohen DM, Yang MT, Chen CS. Measuring cell-cell tugging forces using bowtie-patterned mPADs (microarray post detectors). Methods in Molecular Biology (Clifton, N.J.). 1066: 157-68. PMID 23955742 DOI: 10.1007/978-1-62703-604-7_14 |
0.629 |
|
2013 |
Jacquemet G, Morgan MR, Byron A, Humphries JD, Choi CK, Chen CS, Caswell PT, Humphries MJ. Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway. Journal of Cell Science. 126: 4121-35. PMID 23843620 DOI: 10.1242/Jcs.121988 |
0.362 |
|
2013 |
Wang C, Baker BM, Chen CS, Schwartz MA. Endothelial cell sensing of flow direction. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2130-6. PMID 23814115 DOI: 10.1161/Atvbaha.113.301826 |
0.318 |
|
2013 |
Baker BM, Trappmann B, Stapleton SC, Toro E, Chen CS. Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients. Lab On a Chip. 13: 3246-52. PMID 23787488 DOI: 10.1039/C3Lc50493J |
0.804 |
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2013 |
Dumbauld DW, Lee TT, Singh A, Scrimgeour J, Gersbach CA, Zamir EA, Fu J, Chen CS, Curtis JE, Craig SW, GarcÃa AJ. How vinculin regulates force transmission. Proceedings of the National Academy of Sciences of the United States of America. 110: 9788-93. PMID 23716647 DOI: 10.1073/Pnas.1216209110 |
0.661 |
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2013 |
Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA. Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Current Biology : Cb. 23: 1024-30. PMID 23684974 DOI: 10.1016/J.Cub.2013.04.049 |
0.372 |
|
2013 |
Stevens KR, Ungrin MD, Schwartz RE, Ng S, Carvalho B, Christine KS, Chaturvedi RR, Li CY, Zandstra PW, Chen CS, Bhatia SN. InVERT molding for scalable control of tissue microarchitecture. Nature Communications. 4: 1847. PMID 23673632 DOI: 10.1038/Ncomms2853 |
0.404 |
|
2013 |
Wang YK, Chen CS. Cell adhesion and mechanical stimulation in the regulation of mesenchymal stem cell differentiation. Journal of Cellular and Molecular Medicine. 17: 823-32. PMID 23672518 DOI: 10.1111/Jcmm.12061 |
0.389 |
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2013 |
Kim IL, Khetan S, Baker BM, Chen CS, Burdick JA. Fibrous hyaluronic acid hydrogels that direct MSC chondrogenesis through mechanical and adhesive cues. Biomaterials. 34: 5571-80. PMID 23623322 DOI: 10.1016/J.Biomaterials.2013.04.004 |
0.348 |
|
2013 |
Trappmann B, Chen CS. How cells sense extracellular matrix stiffness: a material's perspective. Current Opinion in Biotechnology. 24: 948-53. PMID 23611564 DOI: 10.1016/J.Copbio.2013.03.020 |
0.389 |
|
2013 |
Baranski JD, Chaturvedi RR, Stevens KR, Eyckmans J, Carvalho B, Solorzano RD, Yang MT, Miller JS, Bhatia SN, Chen CS. Geometric control of vascular networks to enhance engineered tissue integration and function. Proceedings of the National Academy of Sciences of the United States of America. 110: 7586-91. PMID 23610423 DOI: 10.1073/Pnas.1217796110 |
0.8 |
|
2013 |
Nguyen DH, Stapleton SC, Yang MT, Cha SS, Choi CK, Galie PA, Chen CS. Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro. Proceedings of the National Academy of Sciences of the United States of America. 110: 6712-7. PMID 23569284 DOI: 10.1073/Pnas.1221526110 |
0.803 |
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2013 |
Eyckmans J, Roberts SJ, Bolander J, Schrooten J, Chen CS, Luyten FP. Mapping calcium phosphate activated gene networks as a strategy for targeted osteoinduction of human progenitors. Biomaterials. 34: 4612-21. PMID 23537666 DOI: 10.1016/J.Biomaterials.2013.03.011 |
0.306 |
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2013 |
Khetan S, Guvendiren M, Legant WR, Cohen DM, Chen CS, Burdick JA. Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels. Nature Materials. 12: 458-65. PMID 23524375 DOI: 10.1038/Nmat3586 |
0.734 |
|
2013 |
Lin GL, Cohen DM, Desai RA, Breckenridge MT, Gao L, Humphries MJ, Chen CS. Activation of beta 1 but not beta 3 integrin increases cell traction forces. Febs Letters. 587: 763-9. PMID 23395612 DOI: 10.1016/J.Febslet.2013.01.068 |
0.718 |
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2013 |
Zhao R, Boudou T, Wang WG, Chen CS, Reich DH. Decoupling cell and matrix mechanics in engineered microtissues using magnetically actuated microcantilevers. Advanced Materials (Deerfield Beach, Fla.). 25: 1699-705. PMID 23355085 DOI: 10.1002/Adma.201203585 |
0.718 |
|
2013 |
Schwartz MA, Chen CS. Cell biology. Deconstructing dimensionality. Science (New York, N.Y.). 339: 402-4. PMID 23349278 DOI: 10.1126/Science.1233814 |
0.382 |
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2013 |
Legant WR, Choi CK, Miller JS, Shao L, Gao L, Betzig E, Chen CS. Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions. Proceedings of the National Academy of Sciences of the United States of America. 110: 881-6. PMID 23277584 DOI: 10.1073/Pnas.1207997110 |
0.73 |
|
2013 |
Mori H, Lo AT, Inman JL, Alcaraz J, Ghajar CM, Mott JD, Nelson CM, Chen CS, Zhang H, Bascom JL, Seiki M, Bissell MJ. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1. Development (Cambridge, England). 140: 343-52. PMID 23250208 DOI: 10.1242/Jcs.130054 |
0.6 |
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2013 |
West AR, Zaman N, Cole DJ, Walker MJ, Legant WR, Boudou T, Chen CS, Favreau JT, Gaudette GR, Cowley EA, Maksym GN. Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L4-16. PMID 23125251 DOI: 10.1152/Ajplung.00168.2012 |
0.724 |
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2013 |
Xu T, Li F, Nguyen DHT, Chen CS, Zhou C, Huang X. Delineating 3D angiogenic sprouting in OCT images via multiple active contours Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 8090: 231-240. DOI: 10.1007/978-3-642-40843-4_25 |
0.684 |
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2012 |
Leight JL, Liu WF, Chaturvedi RR, Chen S, Yang MT, Raghavan S, Chen CS. Manipulation of 3D Cluster Size and Geometry by Release from 2D Micropatterns. Cellular and Molecular Bioengineering. 5: 299-306. PMID 23730348 DOI: 10.1007/S12195-012-0236-9 |
0.789 |
|
2012 |
Eyckmans J, Lin GL, Chen CS. Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells. Biology Open. 1: 1058-68. PMID 23213385 DOI: 10.1242/Bio.20122162 |
0.587 |
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2012 |
Tian WH, Liu TC, Chen CS, Liu LF, Tien JJ. The relationship between depressive symptoms and health service utilization for elderly people in Taiwan. Health Policy (Amsterdam, Netherlands). 108: 256-67. PMID 23102721 DOI: 10.1016/j.healthpol.2012.10.005 |
0.7 |
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2012 |
Wozniak MA, Cheng CQ, Shen CJ, Gao L, Olarerin-George AO, Won KJ, Hogenesch JB, Chen CS. Adhesion regulates MAP kinase/ternary complex factor exchange to control a proliferative transcriptional switch. Current Biology : Cb. 22: 2017-26. PMID 23063436 DOI: 10.1016/J.Cub.2012.08.050 |
0.682 |
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2012 |
Underhill GH, Galie P, Chen CS, Bhatia SN. Bioengineering methods for analysis of cells in vitro. Annual Review of Cell and Developmental Biology. 28: 385-410. PMID 23057744 DOI: 10.1146/Annurev-Cellbio-101011-155709 |
0.391 |
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2012 |
Legant WR, Chen CS, Vogel V. Force-induced fibronectin assembly and matrix remodeling in a 3D microtissue model of tissue morphogenesis. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1164-74. PMID 22961409 DOI: 10.1039/C2Ib20059G |
0.733 |
|
2012 |
Baker BM, Chen CS. Deconstructing the third dimension: how 3D culture microenvironments alter cellular cues. Journal of Cell Science. 125: 3015-24. PMID 22797912 DOI: 10.1242/Jcs.079509 |
0.386 |
|
2012 |
Miller JS, Stevens KR, Yang MT, Baker BM, Nguyen DH, Cohen DM, Toro E, Chen AA, Galie PA, Yu X, Chaturvedi R, Bhatia SN, Chen CS. Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues. Nature Materials. 11: 768-74. PMID 22751181 DOI: 10.1038/Nmat3357 |
0.806 |
|
2012 |
Felton EJ, Copeland CR, Chen CS, Reich DH. Heterotypic cell pair co-culturing on patterned microarrays. Lab On a Chip. 12: 3117-26. PMID 22739471 DOI: 10.1039/C2Lc40349H |
0.637 |
|
2012 |
Sun Y, Chen CS, Fu J. Forcing stem cells to behave: a biophysical perspective of the cellular microenvironment. Annual Review of Biophysics. 41: 519-42. PMID 22404680 DOI: 10.1146/Annurev-Biophys-042910-155306 |
0.414 |
|
2012 |
Lin YC, Kramer CM, Chen CS, Reich DH. Probing cellular traction forces with magnetic nanowires and microfabricated force sensor arrays. Nanotechnology. 23: 075101. PMID 22260885 DOI: 10.1088/0957-4484/23/7/075101 |
0.603 |
|
2012 |
Leight JL, Wozniak MA, Chen S, Lynch ML, Chen CS. Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition. Molecular Biology of the Cell. 23: 781-91. PMID 22238361 DOI: 10.1091/Mbc.E11-06-0537 |
0.743 |
|
2012 |
Boudou T, Legant WR, Mu A, Borochin MA, Thavandiran N, Radisic M, Zandstra PW, Epstein JA, Margulies KB, Chen CS. A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Engineering. Part A. 18: 910-9. PMID 22092279 DOI: 10.1089/Ten.Tea.2011.0341 |
0.726 |
|
2012 |
Wang YK, Yu X, Cohen DM, Wozniak MA, Yang MT, Gao L, Eyckmans J, Chen CS. Bone morphogenetic protein-2-induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tension. Stem Cells and Development. 21: 1176-86. PMID 21967638 DOI: 10.1089/Scd.2011.0293 |
0.6 |
|
2012 |
Zhao R, Boudou T, Chen CS, Reich DH. Magnetic microtissue stretching system to study the mechanobiology of 3d fibroblast populated collagen matrix Asme 2012 Summer Bioengineering Conference, Sbc 2012. 691-692. DOI: 10.1115/SBC2012-80689 |
0.649 |
|
2012 |
Khetan S, Legant WR, Chen CS, Burdick JA. Stem cell fate within 3D hydrogels is mediated by network structure-dependent traction generation Asme 2012 Summer Bioengineering Conference, Sbc 2012. 527-528. DOI: 10.1115/SBC2012-80277 |
0.662 |
|
2012 |
Pathak A, Chen CS, Evans AG, McMeeking RM. Structural mechanics based model for the force-bearing elements within the cytoskeleton of a cell adhered on a bed of posts Journal of Applied Mechanics, Transactions Asme. 79. DOI: 10.1115/1.4006452 |
0.356 |
|
2012 |
Chen CS. Engineered Microenvironments: A Materials Approach to the Regulation of Cell Function Biophysical Journal. 102: 4-7. DOI: 10.1016/J.Bpj.2011.11.2338 |
0.465 |
|
2011 |
Ricart BG, Yang MT, Hunter CA, Chen CS, Hammer DA. Measuring traction forces of motile dendritic cells on micropost arrays. Biophysical Journal. 101: 2620-8. PMID 22261049 DOI: 10.1016/J.Bpj.2011.09.022 |
0.565 |
|
2011 |
Cristancho AG, Schupp M, Lefterova MI, Cao S, Cohen DM, Chen CS, Steger DJ, Lazar MA. Repressor transcription factor 7-like 1 promotes adipogenic competency in precursor cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 16271-6. PMID 21914845 DOI: 10.1073/Pnas.1109409108 |
0.35 |
|
2011 |
Eyckmans J, Boudou T, Yu X, Chen CS. A hitchhiker's guide to mechanobiology. Developmental Cell. 21: 35-47. PMID 21763607 DOI: 10.1016/J.Devcel.2011.06.015 |
0.355 |
|
2011 |
Liaw CC, Liao WY, Chen CS, Jao SC, Wu YC, Shen CN, Wu SH. The calcium-chelating capability of tetrahydrofuranic moieties modulates the cytotoxicity of annonaceous acetogenins. Angewandte Chemie (International Ed. in English). 50: 7885-91. PMID 21744442 DOI: 10.1002/anie.201100717 |
0.342 |
|
2011 |
Shen CJ, Raghavan S, Xu Z, Baranski JD, Yu X, Wozniak MA, Miller JS, Gupta M, Buckbinder L, Chen CS. Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner. Experimental Cell Research. 317: 1860-71. PMID 21640103 DOI: 10.1016/J.Yexcr.2011.05.006 |
0.818 |
|
2011 |
Yang MT, Reich DH, Chen CS. Measurement and analysis of traction force dynamics in response to vasoactive agonists. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 663-74. PMID 21445393 DOI: 10.1039/C0Ib00156B |
0.745 |
|
2011 |
Gao L, Gorski JL, Chen CS. The Cdc42 guanine nucleotide exchange factor FGD1 regulates osteogenesis in human mesenchymal stem cells. The American Journal of Pathology. 178: 969-74. PMID 21356349 DOI: 10.1016/J.Ajpath.2010.11.051 |
0.34 |
|
2011 |
Tee SY, Fu J, Chen CS, Janmey PA. Cell shape and substrate rigidity both regulate cell stiffness Biophysical Journal. 100: L25-L27. PMID 21354386 DOI: 10.1016/J.Bpj.2010.12.3744 |
0.584 |
|
2011 |
Desai RA, Khan MK, Gopal SB, Chen CS. Subcellular spatial segregation of integrin subtypes by patterned multicomponent surfaces. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 560-7. PMID 21298148 DOI: 10.1039/C0Ib00129E |
0.646 |
|
2011 |
Yang MT, Fu J, Wang YK, Desai RA, Chen CS. Assaying stem cell mechanobiology on microfabricated elastomeric substrates with geometrically modulated rigidity. Nature Protocols. 6: 187-213. PMID 21293460 DOI: 10.1038/Nprot.2010.189 |
0.731 |
|
2011 |
Joy A, Cohen DM, Luk A, Anim-Danso E, Chen C, Kohn J. Control of surface chemistry, substrate stiffness, and cell function in a novel terpolymer methacrylate library Langmuir. 27: 1891-1899. PMID 21226505 DOI: 10.1021/La103722M |
0.37 |
|
2011 |
Leslie-Barbick JE, Shen C, Chen C, West JL. Micron-scale spatially patterned, covalently immobilized vascular endothelial growth factor on hydrogels accelerates endothelial tubulogenesis and increases cellular angiogenic responses. Tissue Engineering. Part A. 17: 221-9. PMID 20712418 DOI: 10.1089/Ten.Tea.2010.0202 |
0.546 |
|
2011 |
Fu J, Wang Y, Yang MT, Desai RA, Yu X, Liu Z, Chen CS. Addendum: Mechanical regulation of cell function with geometrically modulated elastomeric substrates Nature Methods. 8: 184-184. DOI: 10.1038/Nmeth0211-184A |
0.751 |
|
2011 |
Lemmon CA, Chen CS, Romer L. Mechanics and Biochemistry of Matrix Assembly: Pulling it all Together Biophysical Journal. 100: 447a. DOI: 10.1016/J.Bpj.2010.12.2635 |
0.697 |
|
2011 |
Legant WR, Miller JS, Blakely BL, Cohen D, Genin GM, Chen CS. A general Approach to Measure Three-Dimensional Forces from Cells Biophysical Journal. 100: 190a. DOI: 10.1016/J.Bpj.2010.12.1258 |
0.816 |
|
2010 |
Legant WR, Miller JS, Blakely BL, Cohen DM, Genin GM, Chen CS. Measurement of mechanical tractions exerted by cells in three-dimensional matrices. Nature Methods. 7: 969-71. PMID 21076420 DOI: 10.1038/Nmeth.1531 |
0.817 |
|
2010 |
Choi CK, Breckenridge MT, Chen CS. Engineered materials and the cellular microenvironment: a strengthening interface between cell biology and bioengineering. Trends in Cell Biology. 20: 705-14. PMID 20965727 DOI: 10.1016/J.Tcb.2010.09.007 |
0.426 |
|
2010 |
Sriraghavan V, Desai RA, Kwon Y, Mrksich M, Chen CS. Micropatterned dynamically adhesive substrates for cell migration Langmuir. 26: 17733-17738. PMID 20886900 DOI: 10.1021/La102955M |
0.739 |
|
2010 |
Liu Z, Sniadecki NJ, Chen CS. Mechanical Forces in Endothelial Cells during Firm Adhesion and Early Transmigration of Human Monocytes. Cellular and Molecular Bioengineering. 3: 50-59. PMID 20862208 DOI: 10.1007/S12195-010-0105-3 |
0.565 |
|
2010 |
Raghavan S, Shen CJ, Desai RA, Sniadecki NJ, Nelson CM, Chen CS. Decoupling diffusional from dimensional control of signaling in 3D culture reveals a role for myosin in tubulogenesis. Journal of Cell Science. 123: 2877-83. PMID 20682635 DOI: 10.1242/Jcs.055079 |
0.783 |
|
2010 |
Fu J, Wang YK, Yang MT, Desai RA, Yu X, Liu Z, Chen CS. Mechanical regulation of cell function with geometrically modulated elastomeric substrates. Nature Methods. 7: 733-6. PMID 20676108 DOI: 10.1038/Nmeth.1487 |
0.771 |
|
2010 |
Grashoff C, Hoffman BD, Brenner MD, Zhou R, Parsons M, Yang MT, McLean MA, Sligar SG, Chen CS, Ha T, Schwartz MA. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature. 466: 263-6. PMID 20613844 DOI: 10.1038/Nature09198 |
0.568 |
|
2010 |
Liu Z, Tan JL, Cohen DM, Yang MT, Sniadecki NJ, Ruiz SA, Nelson CM, Chen CS. Mechanical tugging force regulates the size of cell-cell junctions. Proceedings of the National Academy of Sciences of the United States of America. 107: 9944-9. PMID 20463286 DOI: 10.1073/Pnas.0914547107 |
0.806 |
|
2010 |
Raghavan S, Nelson CM, Baranski JD, Lim E, Chen CS. Geometrically controlled endothelial tubulogenesis in micropatterned gels. Tissue Engineering. Part A. 16: 2255-63. PMID 20180698 DOI: 10.1089/Ten.Tea.2009.0584 |
0.821 |
|
2010 |
Miller JS, Shen CJ, Legant WR, Baranski JD, Blakely BL, Chen CS. Bioactive hydrogels made from step-growth derived PEG-peptide macromers. Biomaterials. 31: 3736-43. PMID 20138664 DOI: 10.1016/J.Biomaterials.2010.01.058 |
0.796 |
|
2010 |
Gao L, McBeath R, Chen CS. Stem cell shape regulates a chondrogenic versus myogenic fate through Rac1 and N-cadherin. Stem Cells (Dayton, Ohio). 28: 564-72. PMID 20082286 DOI: 10.1002/Stem.308 |
0.757 |
|
2010 |
Treiser MD, Yang EH, Gordonov S, Cohen DM, Androulakis IP, Kohn J, Chen CS, Moghe PV. Cytoskeleton-based forecasting of stem cell lineage fates. Proceedings of the National Academy of Sciences of the United States of America. 107: 610-5. PMID 20080726 DOI: 10.1073/Pnas.0909597107 |
0.383 |
|
2009 |
McGarry JP, Fu J, Yang MT, Chen CS, McMeeking RM, Evans AG, Deshpande VS. Simulation of the contractile response of cells on an array of micro-posts. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 367: 3477-97. PMID 19657008 DOI: 10.1098/Rsta.2009.0097 |
0.606 |
|
2009 |
Guilak F, Cohen DM, Estes BT, Gimble JM, Liedtke W, Chen CS. Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell. 5: 17-26. PMID 19570510 DOI: 10.1016/J.Stem.2009.06.016 |
0.399 |
|
2009 |
Legant WR, Pathak A, Yang MT, Deshpande VS, McMeeking RM, Chen CS. Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues. Proceedings of the National Academy of Sciences of the United States of America. 106: 10097-102. PMID 19541627 DOI: 10.1073/Pnas.0900174106 |
0.776 |
|
2009 |
Desai RA, Gao L, Raghavan S, Liu WF, Chen CS. Cell polarity triggered by cell-cell adhesion via E-cadherin. Journal of Cell Science. 122: 905-11. PMID 19258396 DOI: 10.1242/Jcs.028183 |
0.737 |
|
2009 |
Ostuni E, Whitesides GM, Ingber DE, Chen CS. Using self-assembled monolayers to pattern ECM proteins and cells on substrates. Methods in Molecular Biology (Clifton, N.J.). 522: 183-94. PMID 19247618 DOI: 10.1007/978-1-59745-413-1_12 |
0.831 |
|
2009 |
Wozniak MA, Chen CS. Mechanotransduction in development: a growing role for contractility. Nature Reviews. Molecular Cell Biology. 10: 34-43. PMID 19197330 DOI: 10.1038/Nrm2592 |
0.418 |
|
2009 |
Lemmon CA, Chen CS, Romer LH. Cell traction forces direct fibronectin matrix assembly. Biophysical Journal. 96: 729-38. PMID 19167317 DOI: 10.1016/J.Bpj.2008.10.009 |
0.776 |
|
2009 |
Chen CS, Nelson CM, Khauv D, Bennett S, Radisky ES, Hirai Y, Bissell MJ, Radisky DC. Homology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis. The Journal of Biological Chemistry. 284: 6877-84. PMID 19129200 DOI: 10.1074/Jbc.M805908200 |
0.573 |
|
2008 |
Cohen DM, Chen CS. Mechanical control of stem cell differentiation Stembook. PMID 20614621 DOI: 10.3824/Stembook.1.26.1 |
0.385 |
|
2008 |
Chen CS. Mechanotransduction - a field pulling together? Journal of Cell Science. 121: 3285-92. PMID 18843115 DOI: 10.1242/Jcs.023507 |
0.378 |
|
2008 |
Wang AY, Leong S, Liang YC, Huang RC, Chen CS, Yu SM. Immobilization of growth factors on collagen scaffolds mediated by polyanionic collagen mimetic peptides and its effect on endothelial cell morphogenesis. Biomacromolecules. 9: 2929-36. PMID 18816098 DOI: 10.1021/Bm800727Z |
0.363 |
|
2008 |
Ruiz SA, Chen CS. Emergence of patterned stem cell differentiation within multicellular structures. Stem Cells (Dayton, Ohio). 26: 2921-7. PMID 18703661 DOI: 10.1634/Stemcells.2008-0432 |
0.368 |
|
2008 |
Chen CS. Biotechnology: remote control of living cells. Nature Nanotechnology. 3: 13-4. PMID 18654443 DOI: 10.1038/Nnano.2007.431 |
0.329 |
|
2008 |
Gray DS, Liu WF, Shen CJ, Bhadriraju K, Nelson CM, Chen CS. Engineering amount of cell-cell contact demonstrates biphasic proliferative regulation through RhoA and the actin cytoskeleton. Experimental Cell Research. 314: 2846-54. PMID 18652824 DOI: 10.1016/J.Yexcr.2008.06.023 |
0.772 |
|
2008 |
Parker KK, Tan J, Chen CS, Tung L. Myofibrillar architecture in engineered cardiac myocytes. Circulation Research. 103: 340-2. PMID 18635822 DOI: 10.1161/Circresaha.108.182469 |
0.698 |
|
2008 |
Sniadecki NJ, Lamb CM, Liu Y, Chen CS, Reich DH. Magnetic microposts for mechanical stimulation of biological cells: fabrication, characterization, and analysis. The Review of Scientific Instruments. 79: 044302. PMID 18447536 DOI: 10.1063/1.2906228 |
0.614 |
|
2008 |
Chen CS, Hiura Y, Shen CS, Iwai N. Assessment of mitochondrial DNA polymorphisms in salt-sensitive hypertension in Dahl salt-sensitive rats. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 31: 107-15. PMID 18360025 DOI: 10.1291/hypres.31.107 |
0.341 |
|
2008 |
Pirone DM, Qi L, Colecraft H, Chen CS. Spatial patterning of gene expression using surface-immobilized recombinant adenovirus. Biomedical Microdevices. 10: 561-6. PMID 18246428 DOI: 10.1007/S10544-008-9166-7 |
0.339 |
|
2008 |
Fournier AK, Campbell LE, Castagnino P, Liu WF, Chung BM, Weaver VM, Chen CS, Assoian RK. Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion. Journal of Cell Science. 121: 226-33. PMID 18187454 DOI: 10.1242/Jcs.017012 |
0.372 |
|
2008 |
Chen CS, Ingber DE. Tensegrity and mechanoregulation: From skeleton to cytoskeleton | Tensegrity und mechanoregulation: Vom skelett zum zytoskelett Osteopathische Medizin. 9: 4-17. DOI: 10.1016/J.Ostmed.2008.09.010 |
0.543 |
|
2008 |
Shen CJ, Fu J, Chen CS. Patterning Cell and Tissue Function Cellular and Molecular Bioengineering. 1: 15-23. DOI: 10.1007/S12195-008-0005-Y |
0.577 |
|
2007 |
Alom Ruiz S, Chen CS. Microcontact printing: A tool to pattern. Soft Matter. 3: 168-177. PMID 32680260 DOI: 10.1039/B613349E |
0.767 |
|
2007 |
Desai R, Yang M, Sniadecki N, Legant W, Chen C. Microfabricated post-array-detectors (mPADs): an approach to isolate mechanical forces. Journal of Visualized Experiments : Jove. 311. PMID 18989444 DOI: 10.3791/311 |
0.806 |
|
2007 |
Desai R, Yang M, Sniadecki N, Legant W, Chen C. Microfabricated post-array-detectors (mPADs): an approach to isolate mechanical forces. Journal of Visualized Experiments : Jove. 311. PMID 18989444 DOI: 10.3791/311 |
0.806 |
|
2007 |
Gómez-Sjöberg R, Leyrat AA, Pirone DM, Chen CS, Quake SR. Versatile, fully automated, microfluidic cell culture system. Analytical Chemistry. 79: 8557-63. PMID 17953452 DOI: 10.1021/Ac071311W |
0.357 |
|
2007 |
Liu WF, Chen CS. Cellular and multicellular form and function. Advanced Drug Delivery Reviews. 59: 1319-28. PMID 17884241 DOI: 10.1016/J.Addr.2007.08.011 |
0.45 |
|
2007 |
Sniadecki NJ, Anguelouch A, Yang MT, Lamb CM, Liu Z, Kirschner SB, Liu Y, Reich DH, Chen CS. Magnetic microposts as an approach to apply forces to living cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 14553-8. PMID 17804810 DOI: 10.1073/Pnas.0611613104 |
0.749 |
|
2007 |
Liu WF, Nelson CM, Tan JL, Chen CS. Cadherins, RhoA, and Rac1 are differentially required for stretch-mediated proliferation in endothelial versus smooth muscle cells. Circulation Research. 101: e44-52. PMID 17712140 DOI: 10.1161/Circresaha.107.158329 |
0.714 |
|
2007 |
Bhadriraju K, Yang M, Alom Ruiz S, Pirone D, Tan J, Chen CS. Activation of ROCK by RhoA is regulated by cell adhesion, shape, and cytoskeletal tension. Experimental Cell Research. 313: 3616-23. PMID 17673200 DOI: 10.1016/J.Yexcr.2007.07.002 |
0.801 |
|
2007 |
Sniadecki NJ, Chen CS. Microfabricated silicone elastomeric post arrays for measuring traction forces of adherent cells. Methods in Cell Biology. 83: 313-28. PMID 17613314 DOI: 10.1016/S0091-679X(07)83013-5 |
0.428 |
|
2007 |
Chen CS. Bait and switch: synthetic GEFs divert an input signal to diverse cellular responses. Developmental Cell. 13: 9-10. PMID 17609105 DOI: 10.1016/J.Devcel.2007.06.007 |
0.327 |
|
2007 |
Nelson CM, Liu WF, Chen CS. Manipulation of cell-cell adhesion using bowtie-shaped microwells. Methods in Molecular Biology (Clifton, N.J.). 370: 1-10. PMID 17416983 DOI: 10.1007/978-1-59745-353-0_1 |
0.606 |
|
2007 |
Chen CS. Separate but not equal: differential mechanical roles for Myosin isoforms. Biophysical Journal. 92: 2984-5. PMID 17325018 DOI: 10.1529/Biophysj.106.100065 |
0.377 |
|
2007 |
Alom Ruiz S, Chen CS. Microcontact printing: A tool to pattern Soft Matter. 3: 168-177. DOI: 10.1039/b613349e |
0.759 |
|
2007 |
Yang MT, Sniadecki NJ, Chen CS. Geometric considerations of micro- To nanoscale elastomeric post arrays to study cellular traction forces Advanced Materials. 19: 3119-3123. DOI: 10.1002/Adma.200701956 |
0.614 |
|
2006 |
Pirone DM, Liu WF, Ruiz SA, Gao L, Raghavan S, Lemmon CA, Romer LH, Chen CS. An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling. The Journal of Cell Biology. 174: 277-88. PMID 16847103 DOI: 10.1083/Jcb.200510062 |
0.797 |
|
2006 |
Vandenberghe LH, Wang L, Somanathan S, Zhi Y, Figueredo J, Calcedo R, Sanmiguel J, Desai RA, Chen CS, Johnston J, Grant RL, Gao G, Wilson JM. Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid. Nature Medicine. 12: 967-71. PMID 16845388 DOI: 10.1038/Nm1445 |
0.589 |
|
2006 |
Liu WF, Nelson CM, Pirone DM, Chen CS. E-cadherin engagement stimulates proliferation via Rac1. The Journal of Cell Biology. 173: 431-41. PMID 16682529 DOI: 10.1083/Jcb.200510087 |
0.556 |
|
2006 |
Sniadecki NJ, Desai RA, Ruiz SA, Chen CS. Nanotechnology for cell-substrate interactions. Annals of Biomedical Engineering. 34: 59-74. PMID 16525764 DOI: 10.1007/S10439-005-9006-3 |
0.652 |
|
2006 |
Spector A, Jean R, Chen C. Finite-element model of the adhesion-cytoskeleton-nucleus mechanotrasnduction pathway in endothelial cells Journal of Biomechanics. 39: S398. DOI: 10.1016/S0021-9290(06)84613-0 |
0.336 |
|
2005 |
Lemmon CA, Sniadecki NJ, Ruiz SA, Tan JL, Romer LH, Chen CS. Shear force at the cell-matrix interface: enhanced analysis for microfabricated post array detectors. Mechanics & Chemistry of Biosystems : McB. 2: 1-16. PMID 16708468 |
0.802 |
|
2005 |
Jean RP, Chen CS, Spector AA. Finite-element analysis of the adhesion-cytoskeleton-nucleus mechanotransduction pathway during endothelial cell rounding: axisymmetric model. Journal of Biomechanical Engineering. 127: 594-600. PMID 16121529 DOI: 10.1115/1.1933997 |
0.386 |
|
2005 |
Nelson CM, Jean RP, Tan JL, Liu WF, Sniadecki NJ, Spector AA, Chen CS. Emergent patterns of growth controlled by multicellular form and mechanics. Proceedings of the National Academy of Sciences of the United States of America. 102: 11594-9. PMID 16049098 DOI: 10.1073/Pnas.0502575102 |
0.698 |
|
2005 |
Herndon TM, Pirone DM, Tsokos GC, Chen CS. T cell-to-T cell clustering enhances NF-kappaB activity by a PI3K signal mediated by Cbl-b and Rho. Biochemical and Biophysical Research Communications. 332: 1133-9. PMID 15922296 DOI: 10.1016/J.Bbrc.2005.05.064 |
0.307 |
|
2005 |
Tanase M, Felton EJ, Gray DS, Hultgren A, Chen CS, Reich DH. Assembly of multicellular constructs and microarrays of cells using magnetic nanowires. Lab On a Chip. 5: 598-605. PMID 15915251 DOI: 10.1039/B500243E |
0.794 |
|
2005 |
Yim EK, Reano RM, Pang SW, Yee AF, Chen CS, Leong KW. Nanopattern-induced changes in morphology and motility of smooth muscle cells. Biomaterials. 26: 5405-13. PMID 15814139 DOI: 10.1016/J.Biomaterials.2005.01.058 |
0.396 |
|
2005 |
Hultgren A, Tanase M, Felton EJ, Bhadriraju K, Salem AK, Chen CS, Reich DH. Optimization of yield in magnetic cell separations using nickel nanowires of different lengths. Biotechnology Progress. 21: 509-15. PMID 15801791 DOI: 10.1021/Bp049734W |
0.807 |
|
2005 |
Wang AY, Mo X, Chen CS, Yu SM. Facile modification of collagen directed by collagen mimetic peptides. Journal of the American Chemical Society. 127: 4130-1. PMID 15783169 DOI: 10.1021/Ja0431915 |
0.358 |
|
2005 |
Chen CS, Jiang X, Whitesides GM. Microengineering the Environment of Mammalian Cells in Culture Mrs Bulletin. 30: 194-201. DOI: 10.1557/Mrs2005.52 |
0.652 |
|
2005 |
Liu WF, Chen CS. Engineering biomaterials to control cell function Materials Today. 8: 28-35. DOI: 10.1016/S1369-7021(05)71222-0 |
0.351 |
|
2004 |
Pirone DM, Chen CS. Strategies for engineering the adhesive microenvironment. Journal of Mammary Gland Biology and Neoplasia. 9: 405-17. PMID 15838609 DOI: 10.1007/S10911-004-1410-Z |
0.454 |
|
2004 |
Jean RP, Gray DS, Spector AA, Chen CS. Characterization of the nuclear deformation caused by changes in endothelial cell shape. Journal of Biomechanical Engineering. 126: 552-8. PMID 15648807 DOI: 10.1115/1.1800559 |
0.635 |
|
2004 |
Tan JL, Liu W, Nelson CM, Raghavan S, Chen CS. Simple approach to micropattern cells on common culture substrates by tuning substrate wettability. Tissue Engineering. 10: 865-72. PMID 15265304 DOI: 10.1089/1076327041348365 |
0.773 |
|
2004 |
Chen CS, Tan J, Tien J. Mechanotransduction at cell-matrix and cell-cell contacts. Annual Review of Biomedical Engineering. 6: 275-302. PMID 15255771 DOI: 10.1146/Annurev.Bioeng.6.040803.140040 |
0.833 |
|
2004 |
Gray DS, Tan JL, Voldman J, Chen CS. Dielectrophoretic registration of living cells to a microelectrode array. Biosensors & Bioelectronics. 19: 1765-74. PMID 15198083 DOI: 10.1016/J.Bios.2004.03.016 |
0.72 |
|
2004 |
Nelson CM, Pirone DM, Tan JL, Chen CS. Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA. Molecular Biology of the Cell. 15: 2943-53. PMID 15075376 DOI: 10.1091/Mbc.E03-10-0745 |
0.734 |
|
2004 |
McBeath R, Pirone DM, Nelson CM, Bhadriraju K, Chen CS. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Developmental Cell. 6: 483-95. PMID 15068789 DOI: 10.1016/S1534-5807(04)00075-9 |
0.794 |
|
2004 |
Gray DS, Tan JL, Voldman J, Chen CS. Dielectrophoretic registration of living cells to a microelectrode array. Biosensors & Bioelectronics. 19: 771-80. PMID 14709396 DOI: 10.1016/j.bios.2003.08.013 |
0.698 |
|
2004 |
Hultgren A, Tanase M, Chen CS, Reich DH. High-yield cell separations using magnetic nanowires Ieee Transactions On Magnetics. 40: 2988-2990. DOI: 10.1109/Tmag.2004.830406 |
0.801 |
|
2004 |
Raghavan S, Chen CS. Micropatterned environments in cell biology Advanced Materials. 16: 1303-1313. DOI: 10.1002/Adma.200400594 |
0.555 |
|
2004 |
Gray DS, Tien J, Chen CS. High‐Conductivity Elastomeric Electronics Advanced Materials. 16: 393-397. DOI: 10.1002/Adma.200306107 |
0.746 |
|
2003 |
Gray DS, Tien J, Chen CS. Repositioning of cells by mechanotaxis on surfaces with micropatterned Young's modulus. Journal of Biomedical Materials Research. Part A. 66: 605-14. PMID 12918044 DOI: 10.1002/Jbm.A.10585 |
0.824 |
|
2003 |
Nelson CM, Chen CS. VE-cadherin simultaneously stimulates and inhibits cell proliferation by altering cytoskeletal structure and tension. Journal of Cell Science. 116: 3571-81. PMID 12876221 DOI: 10.1242/Jcs.00680 |
0.61 |
|
2003 |
Chen CS, Alonso JL, Ostuni E, Whitesides GM, Ingber DE. Cell shape provides global control of focal adhesion assembly. Biochemical and Biophysical Research Communications. 307: 355-61. PMID 12859964 DOI: 10.1016/S0006-291X(03)01165-3 |
0.825 |
|
2003 |
Tan JL, Tien J, Pirone DM, Gray DS, Bhadriraju K, Chen CS. Cells lying on a bed of microneedles: an approach to isolate mechanical force. Proceedings of the National Academy of Sciences of the United States of America. 100: 1484-9. PMID 12552122 DOI: 10.1073/Pnas.0235407100 |
0.825 |
|
2003 |
Reich DH, Tanase M, Hultgren A, Bauer LA, Chen CS, Meyer GJ. Biological applications of multifunctional magnetic nanowires (invited) Journal of Applied Physics. 93: 7275-7280. DOI: 10.1063/1.1558672 |
0.772 |
|
2003 |
Hultgren A, Tanase M, Chen CS, Meyer GJ, Reich DH. Cell manipulation using magnetic nanowires Journal of Applied Physics. 93: 7554-7556. DOI: 10.1063/1.1556204 |
0.785 |
|
2003 |
Birenbaum NS, Lai BT, Chen CS, Reich DH, Meyer GJ. Selective noncovalent adsorption of protein to bifunctional metallic nanowire surfaces Langmuir. 19: 9580-9582. DOI: 10.1021/La035657N |
0.541 |
|
2003 |
Nelson CM, Raghavan S, Tan JL, Chen CS. Degradation of micropatterned surfaces by cell-dependent and -independent processes Langmuir. 19: 1493-1499. DOI: 10.1021/La026178B |
0.76 |
|
2002 |
Bhadriraju K, Chen CS. Engineering cellular microenvironments to improve cell-based drug testing. Drug Discovery Today. 7: 612-20. PMID 12047872 DOI: 10.1016/S1359-6446(02)02273-0 |
0.435 |
|
2002 |
Nelson CM, Chen CS. Cell-cell signaling by direct contact increases cell proliferation via a PI3K-dependent signal. Febs Letters. 514: 238-42. PMID 11943158 DOI: 10.1016/S0014-5793(02)02370-0 |
0.605 |
|
2002 |
Tien J, Chen CS. Patterning the cellular microenvironment. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 21: 95-8. PMID 11935995 DOI: 10.1109/MEMB.2002.993201 |
0.737 |
|
2002 |
Tien J, Nelson CM, Chen CS. Fabrication of aligned microstructures with a single elastomeric stamp. Proceedings of the National Academy of Sciences of the United States of America. 99: 1758-62. PMID 11842197 DOI: 10.1073/Pnas.042493399 |
0.777 |
|
2002 |
Tan JL, Tien J, Chen CS. Microcontact printing of proteins on mixed self-assembled monolayers Langmuir. 18: 519-523. DOI: 10.1021/La011351+ |
0.53 |
|
2001 |
Ostuni E, Chen CS, Ingber DE, Whitesides GM. Selective Deposition of Proteins and Cells in Arrays of Microwells Langmuir. 17: 2828-2834. DOI: 10.1021/La001372O |
0.809 |
|
2000 |
Chen CS, Ostuni E, Whitesides GM, Ingber DE. Using self-assembled monolayers to pattern ECM proteins and cells on substrates. Methods in Molecular Biology (Clifton, N.J.). 139: 209-19. PMID 10840789 DOI: 10.1385/1-59259-063-2:209 |
0.79 |
|
2000 |
Ostuni E, Kane R, Chen CS, Ingber DE, Whitesides GM. Patterning mammalian cells using elastomeric membranes Langmuir. 16: 7811-7819. DOI: 10.1021/La000382M |
0.795 |
|
1999 |
Dike LE, Chen CS, Mrksich M, Tien J, Whitesides GM, Ingber DE. Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates. In Vitro Cellular & Developmental Biology. Animal. 35: 441-8. PMID 10501083 DOI: 10.1007/S11626-999-0050-4 |
0.824 |
|
1999 |
Chen CS, Brangwynne C, Ingber DE. Pictures in cell biology: squaring up to the cell-shape debate. Trends in Cell Biology. 9: 283. PMID 10438233 DOI: 10.1016/S0962-8924(99)01551-2 |
0.673 |
|
1999 |
Chen CS, Ingber DE. Tensegrity and mechanoregulation: from skeleton to cytoskeleton. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 7: 81-94. PMID 10367017 DOI: 10.1053/Joca.1998.0164 |
0.637 |
|
1999 |
Bhatia SN, Chen CS. Tissue Engineering at the Micro-Scale Biomedical Microdevices. 2: 131-144. DOI: 10.1023/A:1009949704750 |
0.347 |
|
1998 |
Huang S, Chen CS, Ingber DE. Control of cyclin D1, p27(Kip1), and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension. Molecular Biology of the Cell. 9: 3179-93. PMID 9802905 DOI: 10.1091/Mbc.9.11.3179 |
0.678 |
|
1998 |
Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE. Micropatterned surfaces for control of cell shape, position, and function. Biotechnology Progress. 14: 356-63. PMID 9622515 DOI: 10.1021/Bp980031M |
0.796 |
|
1998 |
Chicurel ME, Chen CS, Ingber DE. Cellular control lies in the balance of forces. Current Opinion in Cell Biology. 10: 232-9. PMID 9561847 DOI: 10.1016/S0955-0674(98)80145-2 |
0.639 |
|
1998 |
Roberts C, Chen CS, Mrksich M, Martichonok V, Ingber DE, Whitesides GM. Using mixed self-assembled monolayers presenting RGD and (EG)3OH groups to characterize long-term attachment of bovine capillary endothelial cells to surfaces Journal of the American Chemical Society. 120: 6548-6555. DOI: 10.1021/Ja972467O |
0.753 |
|
1997 |
Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE. Geometric control of cell life and death. Science (New York, N.Y.). 276: 1425-8. PMID 9162012 DOI: 10.1126/Science.276.5317.1425 |
0.791 |
|
1997 |
Maniotis AJ, Chen CS, Ingber DE. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proceedings of the National Academy of Sciences of the United States of America. 94: 849-54. PMID 9023345 DOI: 10.1073/Pnas.94.3.849 |
0.639 |
|
1996 |
Mrksich M, Chen CS, Xia Y, Dike LE, Ingber DE, Whitesides GM. Controlling cell attachment on contoured surfaces with self-assembled monolayers of alkanethiolates on gold. Proceedings of the National Academy of Sciences of the United States of America. 93: 10775-8. PMID 8855256 DOI: 10.1073/Pnas.93.20.10775 |
0.763 |
|
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