Year |
Citation |
Score |
2020 |
Guirao-Abad JP, Weichert M, Albee A, Deck K, Askew DS. A Human IRE1 Inhibitor Blocks the Unfolded Protein Response in the Pathogenic Fungus Aspergillus fumigatus and Suggests Noncanonical Functions within the Pathway. Msphere. 5. PMID 33087521 DOI: 10.1128/mSphere.00879-20 |
0.33 |
|
2020 |
Weichert M, Guirao-Abad J, Aimanianda V, Krishnan K, Grisham C, Snyder P, Sheehan A, Abbu RR, Liu H, Filler SG, Gruenstein EI, Latgé JP, Askew DS. Functional Coupling between the Unfolded Protein Response and Endoplasmic Reticulum/Golgi Ca-ATPases Promotes Stress Tolerance, Cell Wall Biosynthesis, and Virulence of Aspergillus fumigatus. Mbio. 11. PMID 32487759 DOI: 10.1128/Mbio.01060-20 |
0.355 |
|
2015 |
Raj S, Krishnan K, Askew DS, Helynck O, Suzanne P, Lesnard A, Rault S, Zeidler U, d'Enfert C, Latgé JP, Munier-Lehmann H, Saveanu C. Toxicity of a novel antifungal compound is modulated by ERAD components. Antimicrobial Agents and Chemotherapy. PMID 26666917 DOI: 10.1128/Aac.02239-15 |
0.431 |
|
2014 |
Krishnan K, Askew DS. Endoplasmic reticulum stress and fungal pathogenesis. Fungal Biology Reviews. 28: 29-35. PMID 25419229 DOI: 10.1016/J.Fbr.2014.07.001 |
0.413 |
|
2014 |
Krishnan K, Ren Z, Losada L, Nierman WC, Lu LJ, Askew DS. Polysome profiling reveals broad translatome remodeling during endoplasmic reticulum (ER) stress in the pathogenic fungus Aspergillus fumigatus. Bmc Genomics. 15: 159. PMID 24568630 DOI: 10.1186/1471-2164-15-159 |
0.381 |
|
2014 |
Askew DS. Endoplasmic reticulum stress and fungal pathogenesis converge. Virulence. 5: 331-3. PMID 24504109 DOI: 10.4161/Viru.28051 |
0.403 |
|
2014 |
Krishnan K, Askew DS. The fungal UPR: a regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus. Virulence. 5: 334-40. PMID 24189125 DOI: 10.4161/Viru.26571 |
0.389 |
|
2013 |
Powers-Fletcher MV, Feng X, Krishnan K, Askew DS. Deletion of the sec4 homolog srgA from Aspergillus fumigatus is associated with an impaired stress response, attenuated virulence and phenotypic heterogeneity. Plos One. 8: e66741. PMID 23785510 DOI: 10.1371/Journal.Pone.0066741 |
0.433 |
|
2013 |
Krishnan K, Feng X, Powers-Fletcher MV, Bick G, Richie DL, Woollett LA, Askew DS. Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen Aspergillus fumigatus. Eukaryotic Cell. 12: 512-9. PMID 23355008 DOI: 10.1128/Ec.00319-12 |
0.439 |
|
2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Askew DS, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.521 |
|
2012 |
Gravelat FN, Askew DS, Sheppard DC. Targeted gene deletion in Aspergillus fumigatus using the hygromycin-resistance split-marker approach. Methods in Molecular Biology (Clifton, N.J.). 845: 119-30. PMID 22328371 DOI: 10.1007/978-1-61779-539-8_8 |
0.329 |
|
2011 |
Powers-Fletcher MV, Jambunathan K, Brewer JL, Krishnan K, Feng X, Galande AK, Askew DS. Impact of the lectin chaperone calnexin on the stress response, virulence and proteolytic secretome of the fungal pathogen Aspergillus fumigatus. Plos One. 6: e28865. PMID 22163332 DOI: 10.1371/Journal.Pone.0028865 |
0.396 |
|
2011 |
Feng X, Krishnan K, Richie DL, Aimanianda V, Hartl L, Grahl N, Powers-Fletcher MV, Zhang M, Fuller KK, Nierman WC, Lu LJ, Latgé JP, Woollett L, Newman SL, Cramer RA, ... ... Askew DS, et al. HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus. Plos Pathogens. 7: e1002330. PMID 22028661 DOI: 10.1371/Journal.Ppat.1002330 |
0.433 |
|
2011 |
Richie DL, Feng X, Hartl L, Aimanianda V, Krishnan K, Powers-Fletcher MV, Watson DS, Galande AK, White SM, Willett T, Latgé JP, Rhodes JC, Askew DS. The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR). Virulence. 2: 12-21. PMID 21217201 DOI: 10.4161/Viru.2.1.13345 |
0.464 |
|
2011 |
Fuller KK, Richie DL, Feng X, Krishnan K, Stephens TJ, Wikenheiser-Brokamp KA, Askew DS, Rhodes JC. Divergent Protein Kinase A isoforms co-ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus. Molecular Microbiology. 79: 1045-62. PMID 21210869 DOI: 10.1111/J.1365-2958.2010.07509.X |
0.393 |
|
2011 |
Richie DL, Feng X, Krishnan K, Askew DS. Secretion stress and antifungal resistance: an Achilles' heel of Aspergillus fumigatus? Medical Mycology. 49: S101-6. PMID 20608779 DOI: 10.3109/13693786.2010.497504 |
0.39 |
|
2009 |
Richie DL, Hartl L, Aimanianda V, Winters MS, Fuller KK, Miley MD, White S, McCarthy JW, Latgé JP, Feldmesser M, Rhodes JC, Askew DS. A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus. Plos Pathogens. 5: e1000258. PMID 19132084 DOI: 10.1371/Journal.Ppat.1000258 |
0.442 |
|
2009 |
Fuller KK, Zhao W, Askew DS, Rhodes JC. Deletion of the protein kinase A regulatory subunit leads to deregulation of mitochondrial activation and nuclear duplication in Aspergillus fumigatus. Eukaryotic Cell. 8: 271-7. PMID 19124579 DOI: 10.1128/Ec.00391-08 |
0.393 |
|
2008 |
Richie DL, Askew DS. Autophagy in the filamentous fungus Aspergillus fumigatus. Methods in Enzymology. 451: 241-50. PMID 19185725 DOI: 10.1016/S0076-6879(08)03217-5 |
0.352 |
|
2008 |
Palmer GE, Askew DS, Williamson PR. The diverse roles of autophagy in medically important fungi. Autophagy. 4: 982-8. PMID 18927489 DOI: 10.4161/Auto.7075 |
0.332 |
|
2008 |
Fortwendel JR, Fuller KK, Stephens TJ, Bacon WC, Askew DS, Rhodes JC. Aspergillus fumigatus RasA regulates asexual development and cell wall integrity. Eukaryotic Cell. 7: 1530-9. PMID 18606827 DOI: 10.1128/Ec.00080-08 |
0.382 |
|
2008 |
Askew DS. Aspergillus fumigatus: virulence genes in a street-smart mold. Current Opinion in Microbiology. 11: 331-7. PMID 18579432 DOI: 10.1016/J.Mib.2008.05.009 |
0.344 |
|
2008 |
Bhabhra R, Richie DL, Kim HS, Nierman WC, Fortwendel J, Aris JP, Rhodes JC, Askew DS. Impaired ribosome biogenesis disrupts the integration between morphogenesis and nuclear duplication during the germination of Aspergillus fumigatus. Eukaryotic Cell. 7: 575-83. PMID 18296619 DOI: 10.1128/Ec.00412-07 |
0.432 |
|
2008 |
Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 4: 151-75. PMID 18188003 DOI: 10.4161/Auto.5338 |
0.317 |
|
2008 |
Richie DL, Askew DS. Autophagy: a role in metal ion homeostasis? Autophagy. 4: 115-7. PMID 18032915 DOI: 10.4161/Auto.5238 |
0.324 |
|
2007 |
Richie DL, Fuller KK, Fortwendel J, Miley MD, McCarthy JW, Feldmesser M, Rhodes JC, Askew DS. Unexpected link between metal ion deficiency and autophagy in Aspergillus fumigatus. Eukaryotic Cell. 6: 2437-47. PMID 17921348 DOI: 10.1128/Ec.00224-07 |
0.369 |
|
2007 |
Richie DL, Miley MD, Bhabhra R, Robson GD, Rhodes JC, Askew DS. The Aspergillus fumigatus metacaspases CasA and CasB facilitate growth under conditions of endoplasmic reticulum stress. Molecular Microbiology. 63: 591-604. PMID 17176258 DOI: 10.1111/J.1365-2958.2006.05534.X |
0.398 |
|
2007 |
Fortwendel J, Zhao W, Bhabhra R, Park S, Perlin DS, Askew DS, Rhodes JC. Erratum: A fungus-specific ras homolog contributes to the hyphal growth and virulence of Aspergillus fumigatus (EukaryotiC Cell (2005) 4, (1982-1989)) Eukaryotic Cell. 6. DOI: 10.1128/Ec.00389-06 |
0.317 |
|
2006 |
Zhao W, Panepinto JC, Fortwendel JR, Fox L, Oliver BG, Askew DS, Rhodes JC. Deletion of the regulatory subunit of protein kinase A in Aspergillus fumigatus alters morphology, sensitivity to oxidative damage, and virulence. Infection and Immunity. 74: 4865-74. PMID 16861675 DOI: 10.1128/Iai.00565-06 |
0.376 |
|
2006 |
Bhabhra R, Zhao W, Rhodes JC, Askew DS. Nucleolar localization of Aspergillus fumigatus CgrA is temperature-dependent. Fungal Genetics and Biology : Fg & B. 43: 1-7. PMID 16314125 DOI: 10.1016/J.Fgb.2005.07.005 |
0.326 |
|
2005 |
Fortwendel JR, Zhao W, Bhabhra R, Park S, Perlin DS, Askew DS, Rhodes JC. A fungus-specific ras homolog contributes to the hyphal growth and virulence of Aspergillus fumigatus. Eukaryotic Cell. 4: 1982-9. PMID 16339716 DOI: 10.1128/Ec.4.12.1982-1989.2005 |
0.389 |
|
2005 |
Bhabhra R, Askew DS. Thermotolerance and virulence of Aspergillus fumigatus: Role of the fungal nucleolus Medical Mycology. 43. PMID 16110798 DOI: 10.1080/13693780400029486 |
0.357 |
|
2005 |
Vogt K, Bhabhra R, Rhodes JC, Askew DS. Doxycycline-regulated gene expression in the opportunistic fungal pathogen Aspergillus fumigatus. Bmc Microbiology. 5: 1. PMID 15649330 DOI: 10.1186/1471-2180-5-1 |
0.351 |
|
2004 |
Bhabhra R, Miley MD, Mylonakis E, Boettner D, Fortwendel J, Panepinto JC, Postow M, Rhodes JC, Askew DS. Disruption of the Aspergillus fumigatus gene encoding nucleolar protein CgrA impairs thermotolerant growth and reduces virulence. Infection and Immunity. 72: 4731-40. PMID 15271935 DOI: 10.1128/Iai.72.8.4731-4740.2004 |
0.419 |
|
2004 |
Fortwendel JR, Panepinto JC, Seitz AE, Askew DS, Rhodes JC. Aspergillus fumigatus rasA and rasB regulate the timing and morphology of asexual development. Fungal Genetics and Biology : Fg & B. 41: 129-39. PMID 14732259 DOI: 10.1016/J.Fgb.2003.10.004 |
0.369 |
|
2003 |
Panepinto JC, Oliver BG, Fortwendel JR, Smith DL, Askew DS, Rhodes JC. Deletion of the Aspergillus fumigatus gene encoding the Ras-related protein RhbA reduces virulence in a model of Invasive pulmonary aspergillosis. Infection and Immunity. 71: 2819-26. PMID 12704156 DOI: 10.1128/Iai.71.5.2819-2826.2003 |
0.421 |
|
2002 |
Oliver BG, Panepinto JC, Askew DS, Rhodes JC. cAMP alteration of growth rate of Aspergillus fumigatus and Aspergillus niger is carbon-source dependent. Microbiology (Reading, England). 148: 2627-33. PMID 12177357 DOI: 10.1099/00221287-148-8-2627 |
0.322 |
|
2002 |
Panepinto JC, Oliver BG, Amlung TW, Askew DS, Rhodes JC. Expression of the Aspergillus fumigatus rheb homologue, rhbA, is induced by nitrogen starvation. Fungal Genetics and Biology : Fg & B. 36: 207-14. PMID 12135576 DOI: 10.1016/S1087-1845(02)00022-1 |
0.362 |
|
2002 |
Oliver BG, Panepinto JC, Fortwendel JR, Smith DL, Askew DS, Rhodes JC. Cloning and expression of pkaC and pkaR, the genes encoding the cAMP-dependent protein kinase of Aspergillus fumigatus. Mycopathologia. 154: 85-91. PMID 12086105 DOI: 10.1023/A:1015533406565 |
0.368 |
|
2002 |
Moy TI, Boettner D, Rhodes JC, Silver PA, Askew DS. Identification of a role for Saccharomyces cerevisiae Cgr1p in pre-rRNA processing and 60S ribosome subunit synthesis. Microbiology (Reading, England). 148: 1081-90. PMID 11932453 DOI: 10.1099/00221287-148-4-1081 |
0.393 |
|
2001 |
Boettner D, Huebner N, Rhodes JC, Askew DS. Molecular cloning of Aspergillus fumigatus CgrA, the ortholog of a conserved fungal nucleolar protein Medical Mycology. 39: 517-521. PMID 11798057 DOI: 10.1080/Mmy.39.6.517.521 |
0.425 |
|
2001 |
Rhodes JC, Oliver BG, Askew DS, Amlung TW. Identification of genes of Aspergillus fumigatus up-regulated during growth on endothelial cells Medical Mycology. 39: 253-260. PMID 11446528 DOI: 10.1080/Mmy.39.3.253.260 |
0.386 |
|
2001 |
Sun J, Boettner D, Huebner N, Xu F, Rhodes JC, Askew DS. Molecular cloning of cgrA, the gene encoding the Aspergillus nidulans ortholog of Saccharomyces cerevisiae CGR1. Current Microbiology. 42: 403-7. PMID 11381331 DOI: 10.1007/S002840010237 |
0.592 |
|
2001 |
Sun J, McFarland M, Boettner D, Panepinto J, Rhodes JC, Askew DS. Cgr1p, a novel nucleolar protein encoded by Saccharomyces cerevisiae orf YGL0292w. Current Microbiology. 42: 65-9. PMID 11116400 DOI: 10.1007/S002840010180 |
0.613 |
|
2000 |
Xu F, Paquette AJ, Anderson DJ, Charalambous A, Askew DS. Identification of a cell type-specific silencer in the first exon of the His-1 gene. Journal of Cellular Biochemistry. 76: 615-24. PMID 10653981 DOI: 10.1002/(Sici)1097-4644(20000315)76:4<615::Aid-Jcb10>3.0.Co;2-Y |
0.356 |
|
1999 |
Askew DS. New insights into the function of noncoding RNA and its potential role in disease pathogenesis Histology and Histopathology. 14: 235-241. PMID 9987668 DOI: 10.14670/Hh-14.235 |
0.327 |
|
1998 |
Sun J, Rhodes JC, Askew DS. Sequencing of a gene encoding a member of the mitochondrial carrier family of transport proteins from Aspergillus nidulans. Dna Sequence : the Journal of Dna Sequencing and Mapping. 9: 1-8. PMID 9773270 DOI: 10.3109/10425179809050019 |
0.56 |
|
1997 |
Li J, Rhodes JC, Askew DS. Evolutionary conservation of putative functional domains in the human homolog of the murine His-1 gene Gene. 184: 169-176. PMID 9031624 DOI: 10.1016/S0378-1119(96)00591-4 |
0.343 |
|
1994 |
Askew DS, Li J, Ihle JN. Retroviral insertions in the murine His-1 locus activate the expression of a novel RNA that lacks an extensive open reading frame Molecular and Cellular Biology. 14: 1743-1751. PMID 8114708 DOI: 10.1128/Mcb.14.3.1743 |
0.341 |
|
1985 |
Askew DS, Eaves AC, Takei F. NHL-30.5: A monoclonal antibody reactive with an acute myeloid leukemia (AML)-associated antigen Leukemia Research. 9: 135-145. PMID 3857404 DOI: 10.1016/0145-2126(85)90027-X |
0.488 |
|
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