Maria Pia Longhese - Publications

Affiliations: 
University of Milano-Bicocca, IT 

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Galli M, Frigerio C, Colombo CV, Casari E, Longhese MP, Clerici M. Exo1 cooperates with Tel1/ATM in promoting recombination events at DNA replication forks. Iscience. 27: 110410. PMID 39081288 DOI: 10.1016/j.isci.2024.110410  0.862
2024 Gnugnoli M, Rinaldi C, Casari E, Pizzul P, Bonetti D, Longhese MP. Proteasome-mediated degradation of long-range nucleases negatively regulates resection of DNA double-strand breaks. Iscience. 27: 110373. PMID 39071887 DOI: 10.1016/j.isci.2024.110373  0.582
2024 Pizzul P, Casari E, Rinaldi C, Gnugnoli M, Mangiagalli M, Tisi R, Longhese MP. Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding. Nucleic Acids Research. PMID 38180815 DOI: 10.1093/nar/gkad1246  0.473
2023 Casari E, Pizzul P, Rinaldi C, Gnugnoli M, Clerici M, Longhese MP. The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation. Cell Reports. 42: 113360. PMID 38007689 DOI: 10.1016/j.celrep.2023.113360  0.846
2023 Rinaldi C, Pizzul P, Casari E, Mangiagalli M, Tisi R, Longhese MP. The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase. Nucleic Acids Research. 51: 1783-1802. PMID 36762474 DOI: 10.1093/nar/gkad062  0.666
2022 Casari E, Gnugnoli M, Rinaldi C, Pizzul P, Colombo CV, Bonetti D, Longhese MP. To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks. Cells. 11. PMID 36291091 DOI: 10.3390/cells11203224  0.606
2022 Pizzul P, Casari E, Gnugnoli M, Rinaldi C, Corallo F, Longhese MP. The DNA damage checkpoint: A tale from budding yeast. Frontiers in Genetics. 13: 995163. PMID 36186482 DOI: 10.3389/fgene.2022.995163  0.581
2021 Gnugnoli M, Casari E, Longhese MP. The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks. Plos Genetics. 17: e1009807. PMID 34520455 DOI: 10.1371/journal.pgen.1009807  0.622
2021 Casari E, Gobbini E, Gnugnoli M, Mangiagalli M, Clerici M, Longhese MP. Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes. Nature Communications. 12: 4750. PMID 34362907 DOI: 10.1038/s41467-021-25090-9  0.795
2021 Bonetti D, Clerici M, Longhese MP. Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends. Current Opinion in Genetics & Development. 71: 72-77. PMID 34311383 DOI: 10.1016/j.gde.2021.07.001  0.852
2021 Marsella A, Gobbini E, Cassani C, Tisi R, Cannavo E, Reginato G, Cejka P, Longhese MP. Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners. Cell Reports. 34: 108906. PMID 33789097 DOI: 10.1016/j.celrep.2021.108906  0.556
2021 Galli M, Frigerio C, Longhese MP, Clerici M. The regulation of the DNA damage response at telomeres: focus on kinases. Biochemical Society Transactions. PMID 33769480 DOI: 10.1042/BST20200856  0.812
2021 Rinaldi C, Pizzul P, Longhese MP, Bonetti D. Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability. Frontiers in Cell and Developmental Biology. 8: 618157. PMID 33505970 DOI: 10.3389/fcell.2020.618157  0.502
2021 Gobbini E, Casari E, Colombo CV, Bonetti D, Longhese MP. The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks. Cell Reports. 33: 108287. PMID 33086066 DOI: 10.1016/j.celrep.2020.108287  0.596
2021 Casari E, Gobbini E, Clerici M, Longhese MP. Resection of a DNA Double-Strand Break by Alkaline Gel Electrophoresis and Southern Blotting. Methods in Molecular Biology (Clifton, N.J.). 2153: 33-45. PMID 32840770 DOI: 10.1007/978-1-0716-0644-5_3  0.824
2020 Bruhn C, Ajazi A, Ferrari E, Lanz MC, Batrin R, Choudhary R, Walvekar A, Laxman S, Longhese MP, Fabre E, Smolka MB, Foiani M. The Rad53-Spt21 and Tel1 axes couple glucose tolerance to histone dosage and subtelomeric silencing. Nature Communications. 11: 4154. PMID 32814778 DOI: 10.1038/S41467-020-17961-4  0.473
2020 Tisi R, Vertemara J, Zampella G, Longhese MP. Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks. Computational and Structural Biotechnology Journal. 18: 1137-1152. PMID 32489527 DOI: 10.1016/J.Csbj.2020.05.013  0.729
2020 Colombo CV, Gnugnoli M, Gobbini E, Longhese MP. How do cells sense DNA lesions Biochemical Society Transactions. 48: 677-691. PMID 32219379 DOI: 10.1042/Bst20191118  0.688
2020 Bonetti D, Rinaldi C, Vertemara J, Notaro M, Pizzul P, Tisi R, Zampella G, Longhese MP. DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends. Nucleic Acids Research. 48: 2424-2441. PMID 31879780 DOI: 10.1093/Nar/Gkz1203  0.651
2019 Menin L, Colombo CV, Maestrini G, Longhese MP, Clerici M. Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase. Genetics. PMID 31391264 DOI: 10.1534/Genetics.119.302391  0.867
2019 Casari E, Rinaldi C, Marsella A, Gnugnoli M, Colombo CV, Bonetti D, Longhese MP. Processing of DNA Double-Strand Breaks by the MRX Complex in a Chromatin Context. Frontiers in Molecular Biosciences. 6: 43. PMID 31231660 DOI: 10.3389/Fmolb.2019.00043  0.686
2019 Cassani C, Vertemara J, Bassani M, Marsella A, Tisi R, Zampella G, Longhese MP. The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation. Nucleic Acids Research. 47: 3550-3567. PMID 30698745 DOI: 10.1093/Nar/Gkz038  0.501
2019 Marsella A, Cassani C, Casari E, Tisi R, Longhese MP. Structure-function relationships of the Mre11 protein in the control of DNA end bridging and processing. Current Genetics. 65: 11-16. PMID 29922906 DOI: 10.1007/S00294-018-0861-5  0.663
2019 Menin L, Colombo CV, Maestrini G, Longhese MP, Clerici M. Supplemental Material for Menin et al., 2019 Genetics. DOI: 10.25386/Genetics.8980337.V1  0.663
2018 Colombo CV, Menin L, Ranieri R, Bonetti D, Clerici M, Longhese MP. Uncoupling Sae2 Functions in Downregulation of Tel1 and Rad53 Signalling Activities. Genetics. PMID 30538107 DOI: 10.1534/Genetics.118.301830  0.854
2018 Gobbini E, Vertemara J, Longhese MP. Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity. Molecular and Cellular Oncology. 5. PMID 30263949 DOI: 10.1080/23723556.2018.1511208  0.681
2018 Bonetti D, Colombo CV, Clerici M, Longhese MP. Processing of DNA Ends in the Maintenance of Genome Stability. Frontiers in Genetics. 9: 390. PMID 30258457 DOI: 10.3389/Fgene.2018.00390  0.84
2018 Gobbini E, Cassani C, Vertemara J, Wang W, Mambretti F, Casari E, Sung P, Tisi R, Zampella G, Longhese MP. The MRX complex regulates Exo1 resection activity by altering DNA end structure. The Embo Journal. PMID 29925516 DOI: 10.15252/Embj.201798588  0.654
2018 Menin L, Ursich S, Trovesi C, Zellweger R, Lopes M, Longhese MP, Clerici M. Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning. Embo Reports. PMID 29739811 DOI: 10.15252/Embr.201745535  0.772
2018 Cassani C, Gobbini E, Vertemara J, Wang W, Marsella A, Sung P, Tisi R, Zampella G, Longhese MP. Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance. Nucleic Acids Research. PMID 29420790 DOI: 10.1093/Nar/Gky086  0.609
2018 Villa M, Bonetti D, Carraro M, Longhese MP. Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR‐defective cells Embo Reports. 19: 351-367. PMID 29301856 DOI: 10.15252/Embr.201744910  0.65
2018 Bonetti D, Longhese MP. Analysis of De Novo Telomere Addition by Southern Blot Methods of Molecular Biology. 1672: 363-373. PMID 29043636 DOI: 10.1007/978-1-4939-7306-4_25  0.608
2017 Ferrari E, Bruhn C, Peretti M, Cassani C, Carotenuto WV, Elgendy M, Shubassi G, Lucca C, Bermejo R, Varasi M, Minucci S, Longhese MP, Foiani M. PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response. Molecular Cell. 67: 266-281.e4. PMID 28648781 DOI: 10.1016/J.Molcel.2017.05.027  0.462
2017 Colombo CV, Trovesi C, Menin L, Longhese MP, Clerici M. The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1. Nucleic Acids Research. 45: 6530-6545. PMID 28472517 DOI: 10.1093/Nar/Gkx347  0.837
2017 Cesena D, Cassani C, Rizzo E, Lisby M, Bonetti D, Longhese MP. Regulation of telomere metabolism by the RNA processing protein Xrn1. Nucleic Acids Research. 45: 3860-3874. PMID 28160602 DOI: 10.1093/Nar/Gkx072  0.581
2016 Gobbini E, Cassani C, Villa M, Bonetti D, Longhese MP. Functions and regulation of the MRX complex at DNA double-strand breaks. Microbial Cell (Graz, Austria). 3: 329-337. PMID 28357369 DOI: 10.15698/Mic2016.08.517  0.693
2016 Villa M, Cassani C, Gobbini E, Bonetti D, Longhese MP. Coupling end resection with the checkpoint response at DNA double-strand breaks. Cellular and Molecular Life Sciences. 73: 3655-3663. PMID 27141941 DOI: 10.1007/S00018-016-2262-6  0.72
2016 Cassani C, Gobbini E, Wang W, Niu H, Clerici M, Sung P, Longhese MP. Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks. Plos Biology. 14: e1002387. PMID 26901759 DOI: 10.1371/Journal.Pbio.1002387  0.869
2015 Gobbini E, Villa M, Gnugnoli M, Menin L, Clerici M, Longhese MP. Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity. Plos Genetics. 11: e1005685. PMID 26584331 DOI: 10.1371/Journal.Pgen.1005685  0.869
2015 Manfrini N, Clerici M, Wery M, Colombo CV, Descrimes M, Morillon A, d'Adda di Fagagna F, Longhese MP. Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae. Elife. 4. PMID 26231041 DOI: 10.7554/Elife.08942  0.823
2015 Bonetti D, Villa M, Gobbini E, Cassani C, Tedeschi G, Longhese MP. Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection Embo Reports. 16: 351-361. PMID 25637499 DOI: 10.15252/Embr.201439764  0.658
2015 Manfrini N, Trovesi C, Wery M, Martina M, Cesena D, Descrimes M, Morillon A, d'Adda di Fagagna F, Longhese MP. RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA. Embo Reports. 16: 221-31. PMID 25527408 DOI: 10.15252/Embr.201439458  0.605
2015 Manfrini N, Clerici M, Wery M, Colombo CV, Descrimes M, Morillon A, Fagagna Fdd, Longhese MP. Author response: Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae Elife. DOI: 10.7554/Elife.08942.016  0.714
2014 Gobbini E, Trovesi C, Cassani C, Longhese MP. Telomere uncapping at the crossroad between cell cycle arrest and carcinogenesis Current Opinion in Clinical Nutrition and Metabolic Care. 1. PMID 27308311 DOI: 10.4161/Mco.29901  0.611
2014 Rossiello F, Herbig U, Longhese MP, Fumagalli M, d'Adda di Fagagna F. Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing. Current Opinion in Genetics & Development. 26: 89-95. PMID 25104620 DOI: 10.1016/J.Gde.2014.06.009  0.688
2014 Martina M, Bonetti D, Villa M, Lucchini G, Longhese MP. Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection. Embo Reports. 15: 695-704. PMID 24692507 DOI: 10.1002/Embr.201338338  0.804
2014 Clerici M, Trovesi C, Galbiati A, Lucchini G, Longhese MP. Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends. The Embo Journal. 33: 198-216. PMID 24357557 DOI: 10.1002/Embj.201386041  0.882
2013 Bonetti D, Martina M, Falcettoni M, Longhese MP. Telomere-end processing: mechanisms and regulation. Chromosoma. PMID 24122006 DOI: 10.1007/S00412-013-0440-Y  0.626
2013 Gobbini E, Cesena D, Galbiati A, Lockhart A, Longhese MP. Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks. Dna Repair. 12: 791-799. PMID 23953933 DOI: 10.1016/J.Dnarep.2013.07.009  0.731
2013 Trovesi C, Manfrini N, Falcettoni M, Longhese MP. Regulation of the DNA Damage Response by Cyclin-Dependent Kinases Journal of Molecular Biology. 425: 4756-4766. PMID 23603016 DOI: 10.1016/J.Jmb.2013.04.013  0.718
2013 Bonetti D, Anbalagan S, Lucchini G, Clerici M, Longhese MP. Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends Embo Journal. 32: 275-289. PMID 23222485 DOI: 10.1038/Emboj.2012.327  0.878
2012 Manfrini N, Gobbini E, Baldo V, Trovesi C, Lucchini G, Longhese MP. G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. Molecular and Cellular Biology. 32: 4971-85. PMID 23045388 DOI: 10.1128/Mcb.00956-12  0.715
2012 Fumagalli M, Rossiello F, Clerici M, Barozzi S, Cittaro D, Kaplunov JM, Bucci G, Dobreva M, Matti V, Beausejour CM, Herbig U, Longhese MP, d'Adda di Fagagna F. Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Nature Cell Biology. 14: 355-65. PMID 22426077 DOI: 10.1038/Ncb2466  0.855
2012 Martina M, Clerici M, Baldo V, Bonetti D, Lucchini G, Longhese MP. A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres. Molecular and Cellular Biology. 32: 1604-17. PMID 22354991 DOI: 10.1128/Mcb.06547-11  0.831
2012 Longhese MP, Anbalagan S, Martina M, Bonetti D. The role of shelterin in maintaining telomere integrity. Frontiers in Bioscience (Landmark Edition). 17: 1715-28. PMID 22201831 DOI: 10.2741/4014  0.871
2012 Fumagalli M, Rossiello F, Clerici M, Barozzi S, Cittaro D, Kaplunov JM, Bucci G, Dobreva M, Matti V, Beausejour CM, Herbig U, Longhese MP, d'Adda di Fagagna F. Erratum: Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation Nature Cell Biology. 14: 555-555. DOI: 10.1038/Ncb0512-555B  0.84
2011 Trovesi C, Falcettoni M, Lucchini G, Clerici M, Longhese MP. Distinct Cdk1 requirements during single-strand annealing, noncrossover, and crossover recombination. Plos Genetics. 7: e1002263. PMID 21901114 DOI: 10.1371/Journal.Pgen.1002263  0.875
2011 Anbalagan S, Bonetti D, Lucchini G, Longhese MP. Rif1 supports the function of the CST complex in yeast telomere capping. Plos Genetics. 7: e1002024. PMID 21437267 DOI: 10.1371/Journal.Pgen.1002024  0.88
2011 Anbalagan S, Bonetti D, Lucchini G, Longhese MP. Rif1 supports the function of the CST complex in yeast telomere capping Plos Genetics. 7. DOI: 10.1371/journal.pgen.1002024  0.874
2010 Bonetti D, Clerici M, Manfrini N, Lucchini G, Longhese MP. The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends. Plos One. 5: e14142. PMID 21152442 DOI: 10.1371/Journal.Pone.0014142  0.857
2010 Longhese MP, Bonetti D, Manfrini N, Clerici M. Mechanisms and regulation of DNA end resection. The Embo Journal. 29: 2864-74. PMID 20647996 DOI: 10.1038/Emboj.2010.165  0.856
2010 Bonetti D, Clerici M, Anbalagan S, Martina M, Lucchini G, Longhese MP. Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeres. Plos Genetics. 6: e1000966. PMID 20523746 DOI: 10.1371/Journal.Pgen.1000966  0.865
2010 Manfrini N, Guerini I, Citterio A, Lucchini G, Longhese MP. Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases. The Journal of Biological Chemistry. 285: 11628-37. PMID 20150422 DOI: 10.1074/Jbc.M110.104083  0.811
2010 Bazzi M, Mantiero D, Trovesi C, Lucchini G, Longhese MP. Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication. Molecular and Cellular Biology. 30: 131-45. PMID 19884341 DOI: 10.1128/Mcb.01000-09  0.858
2009 Bonetti D, Martina M, Clerici M, Lucchini G, Longhese MP. Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres. Molecular Cell. 35: 70-81. PMID 19595717 DOI: 10.1016/J.Molcel.2009.05.015  0.838
2009 Longhese MP, Bonetti D, Guerini I, Manfrini N, Clerici M. DNA double-strand breaks in meiosis: checking their formation, processing and repair. Dna Repair. 8: 1127-38. PMID 19464965 DOI: 10.1016/J.Dnarep.2009.04.005  0.833
2009 Domenico EGd, Auriche C, Viscardi V, Longhese MP, Gilson E, Ascenzioni F. The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions. Dna Repair. 8: 209-218. PMID 19007917 DOI: 10.1016/J.Dnarep.2008.10.005  0.64
2008 Clerici M, Mantiero D, Guerini I, Lucchini G, Longhese MP. The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle. Embo Reports. 9: 810-8. PMID 18600234 DOI: 10.1038/Embor.2008.121  0.872
2008 Cartagena-Lirola H, Guerini I, Manfrini N, Lucchini G, Longhese MP. Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. Molecular and Cellular Biology. 28: 4480-93. PMID 18505828 DOI: 10.1128/Mcb.00375-08  0.789
2008 Longhese MP. DNA damage response at functional and dysfunctional telomeres. Genes & Development. 22: 125-140. PMID 18198332 DOI: 10.1101/Gad.1626908  0.705
2008 Longhese MP, Guerini I, Baldo V, Clerici M. Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis. Dna Repair. 7: 545-57. PMID 17962087 DOI: 10.1016/J.Dnarep.2007.09.006  0.823
2008 Baldo V, Testoni V, Lucchini G, Longhese MP. Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response. Molecular and Cellular Biology. 28: 358-75. PMID 17954565 DOI: 10.1128/Mcb.01214-07  0.789
2007 Viscardi V, Bonetti D, Cartagena-Lirola H, Lucchini G, Longhese MP. MRX-dependent DNA damage response to short telomeres. Molecular Biology of the Cell. 18: 3047-58. PMID 17538011 DOI: 10.1091/Mbc.E07-03-0285  0.803
2007 Mantiero D, Clerici M, Lucchini G, Longhese MP. Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. Embo Reports. 8: 380-7. PMID 17347674 DOI: 10.1038/Sj.Embor.7400911  0.873
2007 Lottersberger F, Panza A, Lucchini G, Longhese MP. Functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations. Molecular and Cellular Biology. 27: 3266-81. PMID 17339336 DOI: 10.1128/Mcb.01767-06  0.713
2006 Cartagena-Lirola H, Guerini I, Viscardi V, Lucchini G, Longhese MP. Budding Yeast Sae2 is an In Vivo Target of the Mec1 and Tel1 Checkpoint Kinases During Meiosis. Cell Cycle (Georgetown, Tex.). 5: 1549-59. PMID 16861895 DOI: 10.4161/Cc.5.14.2916  0.745
2006 Longhese MP, Mantiero D, Clerici M. The cellular response to chromosome breakage. Molecular Microbiology. 60: 1099-108. PMID 16689788 DOI: 10.1111/J.1365-2958.2006.05186.X  0.87
2006 Lottersberger F, Panza A, Lucchini G, Piatti S, Longhese MP. The Saccharomyces cerevisiae 14-3-3 proteins are required for the G1/S transition, actin cytoskeleton organization and cell wall integrity. Genetics. 173: 661-75. PMID 16648583 DOI: 10.1534/Genetics.106.058172  0.816
2006 Clerici M, Mantiero D, Lucchini G, Longhese MP. The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling. Embo Reports. 7: 212-8. PMID 16374511 DOI: 10.1038/Sj.Embor.7400593  0.884
2005 Clerici M, Mantiero D, Lucchini G, Longhese MP. The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends. The Journal of Biological Chemistry. 280: 38631-8. PMID 16162495 DOI: 10.1074/Jbc.M508339200  0.861
2005 Viscardi V, Clerici M, Cartagena-Lirola H, Longhese MP. Telomeres and DNA damage checkpoints. Biochimie. 87: 613-24. PMID 15989978 DOI: 10.1016/J.Biochi.2004.10.022  0.859
2004 Clerici M, Baldo V, Mantiero D, Lottersberger F, Lucchini G, Longhese MP. A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1. Molecular and Cellular Biology. 24: 10126-44. PMID 15542824 DOI: 10.1128/Mcb.24.23.10126-10144.2004  0.857
2004 Baroni E, Viscardi V, Cartagena-Lirola H, Lucchini G, Longhese MP. The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation. Molecular and Cellular Biology. 24: 4151-65. PMID 15121837 DOI: 10.1128/Mcb.24.10.4151-4165.2004  0.825
2004 Giannattasio M, Lazzaro F, Longhese MP, Plevani P, Muzi-Falconi M. Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint. The Embo Journal. 23: 429-38. PMID 14726955 DOI: 10.1038/Sj.Emboj.7600051  0.656
2004 Schramke V, Luciano P, Brevet V, Guillot S, Corda Y, Longhese MP, Gilson E, Géli V. RPA regulates telomerase action by providing Est1p access to chromosome ends. Nature Genetics. 36: 46-54. PMID 14702040 DOI: 10.1038/Ng1284  0.632
2003 Lottersberger F, Rubert F, Baldo V, Lucchini G, Longhese MP. Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress. Genetics. 165: 1717-32. PMID 14704161  0.796
2003 Longhese MP, Clerici M, Lucchini G. The S-phase checkpoint and its regulation in Saccharomyces cerevisiae. Mutation Research. 532: 41-58. PMID 14643428 DOI: 10.1016/J.Mrfmmm.2003.08.009  0.873
2003 Viscardi V, Baroni E, Romano M, Lucchini G, Longhese MP. Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae. Molecular Biology of the Cell. 14: 3126-43. PMID 12925751 DOI: 10.1091/Mbc.E02-11-0719  0.749
2003 Tercero JA, Longhese MP, Diffley JF. A central role for DNA replication forks in checkpoint activation and response. Molecular Cell. 11: 1323-36. PMID 12769855 DOI: 10.1016/S1097-2765(03)00169-2  0.698
2001 Clerici M, Paciotti V, Baldo V, Romano M, Lucchini G, Longhese MP. Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression. The Embo Journal. 20: 6485-6498. PMID 11707419 DOI: 10.1093/Emboj/20.22.6485  0.861
2001 Schramke V, Neecke H, Brevet V, Corda Y, Lucchini G, Longhese MP, Gilson E, Géli V. The set1Delta mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes. Genes & Development. 15: 1845-1858. PMID 11459833 DOI: 10.1101/Gad.193901  0.77
2001 Paciotti V, Clerici M, Scotti M, Lucchini G, Longhese MP. Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway. Molecular and Cellular Biology. 21: 3913-25. PMID 11359899 DOI: 10.1128/Mcb.21.12.3913-3925.2001  0.885
2000 Paciotti V, Clerici M, Lucchini G, Longhese MP. The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast Genes & Development. 14: 2046-2059. DOI: 10.1101/Gad.14.16.2046  0.833
1999 Neecke H, Lucchini G, Longhese MP. Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1‐ and Rad53‐dependent checkpoint in budding yeast The Embo Journal. 18: 4485-4497. PMID 10449414 DOI: 10.1093/Emboj/18.16.4485  0.772
1999 Corda Y, Schramke V, Longhese MP, Smokvina T, Paciotti V, Brevet V, Gilson E, Géli V. Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions Nature Genetics. 21: 204-208. PMID 9988274 DOI: 10.1038/5991  0.623
1998 Longhese MP, Foiani M, Muzi‐Falconi M, Lucchini G, Plevani P. DNA damage checkpoint in budding yeast. The Embo Journal. 17: 5525-5528. PMID 9755152 DOI: 10.1093/Emboj/17.19.5525  0.768
1998 Paciotti V, Lucchini G, Plevani P, Longhese MP. Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p The Embo Journal. 17: 4199-4209. PMID 9670034 DOI: 10.1093/Emboj/17.14.4199  0.812
1998 Teng Y, Longhese M, McDonough G, Waters R. Mutants with changes in different domains of yeast replication protein A exhibit differences in repairing the control region, the transcribed strand and the non-transcribed strand of the Saccharomyces cerevisiae MFA2 gene. Journal of Molecular Biology. 280: 355-363. PMID 9665842 DOI: 10.1006/Jmbi.1998.1872  0.526
1997 Longhese MP, Paciotti V, Fraschini R, Zaccarini R, Plevani P, Lucchini G. The novel DNA damage checkpoint protein Ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast The Embo Journal. 16: 5216-5226. PMID 9311982 DOI: 10.1093/Emboj/16.17.5216  0.813
1996 Longhese MP, Neecke H, Paciotti V, Lucchini G, Plevani P. The 70 kDa subunit of replication protein A is required for the G1/S and intra-S DNA damage checkpoints in budding yeast. Nucleic Acids Research. 24: 3533-3537. PMID 8836179 DOI: 10.1093/Nar/24.18.3533  0.702
1996 Longhese MP, Fraschini R, Plevani P, Lucchini G. Yeast pip3/mec3 mutants fail to delay entry into S phase and to slow DNA replication in response to DNA damage, and they define a functional link between Mec3 and DNA primase. Molecular and Cellular Biology. 16: 3235-3244. PMID 8668138 DOI: 10.1128/Mcb.16.7.3235  0.804
1995 Santocanale C, Neecke H, Longhese MP, Lucchini G, Plevani P. Mutations in the Gene Encoding the 34 kDa Subunit of Yeast Replication Protein A Cause Defective S Phase Progression Journal of Molecular Biology. 254: 595-607. PMID 7500336 DOI: 10.1006/Jmbi.1995.0641  0.812
1994 Longhese MP, Plevani P, Lucchini G. Replication factor A is required in vivo for DNA replication, repair, and recombination. Molecular and Cellular Biology. 14: 7884-7890. PMID 7969128 DOI: 10.1128/Mcb.14.12.7884  0.79
1993 Shimizu K, Santocanale C, Ropp PA, Longhese MP, Plevani P, Lucchini G, Sugino A. Purification and characterization of a new DNA polymerase from budding yeast Saccharomyces cerevisiae. A probable homolog of mammalian DNA polymerase beta. Journal of Biological Chemistry. 268: 27148-27153. DOI: 10.1016/s0021-9258(19)74229-x  0.716
1991 Francesconi S, Longhese MP, Piseri A, Santocanale C, Lucchini G, Plevani P. Mutations in conserved yeast DNA primase domains impair DNA replication in vivo. Proceedings of the National Academy of Sciences of the United States of America. 88: 3877-3881. PMID 2023935 DOI: 10.1073/Pnas.88.9.3877  0.845
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