Yuxing Xia, MD/PhD - Publications

Affiliations: 
2016-2023 Neuroscience University of Florida College of Medicine 
 2023- Neurology University of California, Los Angeles, Los Angeles, CA 

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Xia Y, Bell BM, Giasson BI. Tau Lysine Pseudomethylation Regulates Microtubule Binding and Enhances Prion-like Tau Aggregation. International Journal of Molecular Sciences. 24. PMID 37175990 DOI: 10.3390/ijms24098286  0.265
2022 Xia Y. Role of Ubiquilin-2 in Proteostasis and Tau Aggregation in Tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 42: 6168-6170. PMID 35948434 DOI: 10.1523/JNEUROSCI.0839-22.2022  0.489
2022 Xia Y, Prokop S, Bell BM, Gorion KM, Croft CL, Nasif L, Xu G, Riffe CJ, Manaois AN, Strang KH, Quintin SS, Paterno G, Tansey MG, Borchelt DR, Golde TE, et al. Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice. Communications Biology. 5: 446. PMID 35550593 DOI: 10.1038/s42003-022-03373-1  0.662
2021 Xia Y, Lloyd GM, Giasson BI. Targeted proteolytic products of τ and α-synuclein in neurodegeneration. Essays in Biochemistry. 65: 905-912. PMID 34846537 DOI: 10.1042/EBC20210028  0.775
2021 Lloyd GM, Dhillon JS, Gorion KM, Riffe C, Fromholt SE, Xia Y, Giasson BI, Borchelt DR. Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model. Molecular Neurodegeneration. 16: 63. PMID 34503546 DOI: 10.1186/s13024-021-00486-9  0.789
2021 Hass EW, Sorrentino ZA, Xia Y, Lloyd GM, Trojanowski JQ, Prokop S, Giasson BI. Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies. Acta Neuropathologica Communications. 9: 146. PMID 34454615 DOI: 10.1186/s40478-021-01242-2  0.739
2021 Xia Y, Bell BM, Giasson BI. Tau K321/K353 pseudoacetylation within KXGS motifs regulates tau-microtubule interactions and inhibits aggregation. Scientific Reports. 11: 17069. PMID 34426645 DOI: 10.1038/s41598-021-96627-7  0.654
2021 Xia Y, Prokop S, Giasson BI. "Don't Phos Over Tau": recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer's disease and other tauopathies. Molecular Neurodegeneration. 16: 37. PMID 34090488 DOI: 10.1186/s13024-021-00460-5  0.647
2021 Krumm ZA, Lloyd GM, Francis CP, Nasif LH, Mitchell DA, Golde TE, Giasson BI, Xia Y. Precision therapeutic targets for COVID-19. Virology Journal. 18: 66. PMID 33781287 DOI: 10.1186/s12985-021-01526-y  0.709
2021 Xia Y, Nasif L, Giasson BI. Pathogenic MAPT mutations Q336H and Q336R have isoform-dependent differences in aggregation propensity and microtubule dysfunction. Journal of Neurochemistry. PMID 33772783 DOI: 10.1111/jnc.15358  0.632
2021 Xia Y, Chen Z, Xu G, Borchelt DR, Ayers JI, Giasson BI. Novel SOD1 monoclonal antibodies against the electrostatic loop preferentially detect misfolded SOD1 aggregates. Neuroscience Letters. 742: 135553. PMID 33346076 DOI: 10.1016/j.neulet.2020.135553  0.541
2020 Xia Y. Therapeutic potential of miRNAs in Duchenne muscular dystrophy and other neuromuscular diseases. The Journal of Physiology. PMID 33226636 DOI: 10.1113/JP280999  0.291
2020 Xia Y, Prokop S, Gorion KM, Kim JD, Sorrentino ZA, Bell BM, Manaois AN, Chakrabarty P, Davies P, Giasson BI. Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer's disease and other tauopathies. Acta Neuropathologica Communications. 8: 88. PMID 32571418 DOI: 10.1186/S40478-020-00967-W  0.783
2020 Lloyd GM, Trejo-Lopez JA, Xia Y, McFarland KN, Lincoln SJ, Ertekin-Taner N, Giasson BI, Yachnis AT, Prokop S. Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier - phenotypic variability in autosomal dominant Alzheimer's disease. Acta Neuropathologica Communications. 8: 31. PMID 32164763 DOI: 10.1186/S40478-020-0891-3  0.767
2020 Sorrentino ZA, Xia Y, Gorion KM, Hass E, Giasson BI. Carboxy-terminal truncations of mouse alpha-synuclein alter aggregation and prion-like seeding. Febs Letters. PMID 31912891 DOI: 10.1002/1873-3468.13728  0.779
2019 Xia Y, Sorrentino ZA, Kim JD, Strang KH, Riffe CJ, Giasson BI. Impaired tau-microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations. The Journal of Biological Chemistry. PMID 31653695 DOI: 10.1074/Jbc.Ra119.010178  0.784
2019 Sorrentino ZA, Goodwin MS, Riffe CJ, Dhillon JS, Xia Y, Gorion KM, Vijayaraghavan N, McFarland KN, Golbe LI, Yachnis AT, Giasson BI. Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression. Acta Neuropathologica Communications. 7: 142. PMID 31477175 DOI: 10.1186/S40478-019-0787-2  0.806
2018 Sorrentino ZA, Xia Y, Funk C, Riffe CJ, Rutherford NJ, Diaz CC, Sacino AN, Price ND, Golde TE, Giasson BI, Chakrabarty P. Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration. Neurobiology of Disease. PMID 30195075 DOI: 10.1016/J.Nbd.2018.09.005  0.735
2014 He W, Hu J, Xia Y, Yan R. β-site amyloid precursor protein cleaving enzyme 1(BACE1) regulates Notch signaling by controlling the cleavage of Jagged 1 (Jag1) and Jagged 2 (Jag2) proteins. The Journal of Biological Chemistry. 289: 20630-7. PMID 24907271 DOI: 10.1074/Jbc.M114.579862  0.374
2013 Xia Y, Yan LH, Huang B, Liu M, Liu X, Huang C. Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation. Journal of Neurochemistry. 129: 99-106. PMID 24215460 DOI: 10.1111/jnc.12606  0.423
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