Beatrice Gini, Ph.D.

Affiliations: 
Molecular Pathology Ludwig Institute for Cancer Research, San Diego, CA, United States 
Website:
http://www.ludwigsd.org/labs/molecular_pathology/people/
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"Beatrice Gini"
Cross-listing: Chemistry Tree

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Publications

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Soragni A, Knudsen ES, O'Connor TN, et al. (2025) Acquired resistance in cancer: towards targeted therapeutic strategies. Nature Reviews. Cancer
Caswell DR, Gui P, Mayekar MK, et al. (2023) The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance. Nature Genetics
Gini B, Thomas N, Blakely CM. (2020) Impact of concurrent genomic alterations in epidermal growth factor receptor ()-mutated lung cancer. Journal of Thoracic Disease. 12: 2883-2895
Blakely CM, Watkins TBK, Wu W, et al. (2017) Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers. Nature Genetics
Gu Y, Albuquerque CP, Braas D, et al. (2017) mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT. Molecular Cell
Okimoto RA, Breitenbuecher F, Olivas VR, et al. (2016) Inactivation of Capicua drives cancer metastasis. Nature Genetics
Wei W, Shin YS, Xue M, et al. (2016) Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma. Cancer Cell. 29: 563-73
Tanaka K, Sasayama T, Irino Y, et al. (2015) Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment. The Journal of Clinical Investigation. 125: 1591-602
Shin YS, Wei W, Gini B, et al. (2015) Abstract PR09: Single cell phosphoproteomics identifies adaptive network dynamics of mTOR inhibitor resistance and defines effective combination therapy in glioblastoma Clinical Cancer Research. 21
Gini B, Mischel PS. (2014) Greater than the sum of its parts: single-nucleus sequencing identifies convergent evolution of independent EGFR mutants in GBM. Cancer Discovery. 4: 876-8
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