cached image

Patrick Cras, MD PhD - Publications

Neurology University of Antwerp, Antwerpen, Vlaanderen, Belgium 
dementia, Creutzfeldt-Jakob disease, cerebrospinal fluid, movement disorders and the neuropathology of neurodegenerative diseases

107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mormont E, Bier JC, Bruffaerts R, Cras P, De Deyn P, Deryck O, Engelborghs S, Petrovic M, Picard G, Segers K, Thiery E, Versijpt J, Hanseeuw B. Practices and opinions about disclosure of the diagnosis of Alzheimer's disease to patients with MCI or dementia: a survey among Belgian medical experts in the field of dementia. Acta Neurologica Belgica. PMID 32715405 DOI: 10.1007/S13760-020-01448-6  0.353
2019 Maréchal E, Denoiseux B, Thys E, Cras P, Crosiers D. Impulsive-Compulsive Behaviours in Belgian-Flemish Parkinson's Disease Patients: A Questionnaire-Based Study. Parkinson's Disease. 2019: 7832487. PMID 31011412 DOI: 10.1155/2019/7832487  0.303
2018 Behaeghe O, Mangelschots E, De Vil B, Cras P. A systematic review comparing the diagnostic value of 14-3-3 protein in the cerebrospinal fluid, RT-QuIC and RT-QuIC on nasal brushing in sporadic Creutzfeldt-Jakob disease. Acta Neurologica Belgica. 118: 395-403. PMID 30097826 DOI: 10.1007/s13760-018-0995-8  0.341
2018 Baradaran-Heravi Y, Dillen L, Nguyen HP, Van Mossevelde S, Baets J, De Jonghe P, Engelborghs S, De Deyn PP, Vandenbulcke M, Vandenberghe R, Van Damme P, Cras P, Salmon E, Synofzik M, Heutink P, et al. No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients. Neurobiology of Aging. PMID 29886022 DOI: 10.1016/J.Neurobiolaging.2018.05.005  0.308
2018 Perrone F, Cacace R, Van Mossevelde S, Van den Bossche T, De Deyn PP, Cras P, Engelborghs S, van der Zee J, Van Broeckhoven C. Genetic screening in early-onset dementia patients with unclear phenotype: relevance for clinical diagnosis. Neurobiology of Aging. PMID 29859640 DOI: 10.1016/J.Neurobiolaging.2018.04.015  0.386
2018 De Roeck A, Duchateau L, Van Dongen J, Cacace R, Bjerke M, Van den Bossche T, Cras P, Vandenberghe R, De Deyn PP, Engelborghs S, Van Broeckhoven C, Sleegers K. An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer's disease. Acta Neuropathologica. PMID 29589097 DOI: 10.1007/S00401-018-1841-Z  0.387
2018 Goossens J, Bjerke M, Van Mossevelde S, Van den Bossche T, Goeman J, De Vil B, Sieben A, Martin JJ, Cras P, De Deyn PP, Van Broeckhoven C, van der Zee J, Engelborghs S. Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration. Alzheimer's Research & Therapy. 10: 31. PMID 29559004 DOI: 10.1186/S13195-018-0364-0  0.36
2018 Willemse EAJ, Sieben A, Somers C, Vermeiren Y, Roeck ND, Luyckx J, Broeckhoven CV, Vil BD, Cras P, Deyn PPD, Martin J, Teunissen CE, Engelborghs S, Bjerke M. P4-270: Neurogranin In Cerebrospinal Fluid Is Not Specific To Alzheimer'S Disease Dementia Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.092  0.365
2018 Roeck AD, Duchateau L, Dongen JV, Cacace R, Bjerke M, Bossche TVd, Cras P, Vandenberghe R, Deyn PPD, Engelborghs S, Broeckhoven CV, Sleegers K. O4-01-01: In-Depth Analysis Of An Abca7 Vntr In Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2909  0.333
2017 Goossens J, Bjerke M, Struyfs H, Niemantsverdriet E, Somers C, Van den Bossche T, Van Mossevelde S, De Vil B, Sieben A, Martin JJ, Cras P, Goeman J, De Deyn PP, Van Broeckhoven C, van der Zee J, et al. No added diagnostic value of non-phosphorylated tau fraction (p-taurel) in CSF as a biomarker for differential dementia diagnosis. Alzheimer's Research & Therapy. 9: 49. PMID 28709448 DOI: 10.1186/S13195-017-0275-5  0.361
2017 De Roeck A, Van den Bossche T, van der Zee J, Verheijen J, De Coster W, Van Dongen J, Dillen L, Baradaran-Heravi Y, Heeman B, Sanchez-Valle R, Lladó A, Nacmias B, Sorbi S, Gelpi E, Grau-Rivera O, ... ... Cras P, et al. Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease. Acta Neuropathologica. PMID 28447221 DOI: 10.1007/S00401-017-1714-X  0.348
2017 Roeck AD, Bossche TVd, Verheijen J, Coster WD, Dongen JV, Dillen L, Baradaran-Heravi Y, Engelborghs S, Cras P, Zee Jvd, Broeckhoven CV, Sleegers K. Deleterious Abca7 Mutations Contribute To Early-Onset Alzheimer’S Disease And Are Subject To Transcript Rescue Mechanisms Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.07.220  0.308
2017 Van den Bossche T, De Roeck A, Sieben A, Martin J, Vandenberghe R, Engelborghs S, De Deyn PP, Sleegers K, Cras P, Van Broeckhoven C. CONTRIBUTION OF RARE DELETERIOUS ABCA7 MUTATIONS TO A BELGIAN EARLY-ONSET ALZHEIMER’S DISEASE COHORT Alzheimer's & Dementia. 13: P573-P574. DOI: 10.1016/J.Jalz.2017.07.191  0.331
2017 Mossevelde SV, Zee Jvd, Steger C, Verwilligen L, Cras P, Engelborghs S, Broeckhoven CV. The Mapt P.Arg406Trp Is A Founder Mutation In Belgium And Presents With An Alzheimer Disease Dementia-Like Phenotype Alzheimers & Dementia. 13: 1286. DOI: 10.1016/J.Jalz.2017.06.1940  0.373
2017 Perrone F, Cacace R, Mossevelde SV, Bossche TVd, Sieben A, Engelborghs S, Cras P, Deyn PPD, Martin J, Zee Jvd, Broeckhoven CV. A Prospective Neurogenetic Study On Early-Onset Dementia In Patients With Unclear Initial Diagnosis Of Degenerative Dementia Alzheimers & Dementia. 13: 1284. DOI: 10.1016/J.Jalz.2017.06.1934  0.317
2016 Perrone F, Nguyen HP, Van Mossevelde S, Moisse M, Sieben A, Santens P, De Bleecker J, Vandenbulcke M, Engelborghs S, Baets J, Cras P, Vandenberghe R, De Jonghe P, De Deyn PP, Martin JJ, et al. Investigating the role of ALS genes CHCHD10 and TUBA4A in Belgian FTD-ALS spectrum patients. Neurobiology of Aging. PMID 28069311 DOI: 10.1016/J.Neurobiolaging.2016.12.008  0.357
2016 van der Zee J, Mariën P, Crols R, Van Mossevelde S, Dillen L, Perrone F, Engelborghs S, Verhoeven J, D'aes T, Ceuterick-De Groote C, Sieben A, Versijpt J, Cras P, Martin JJ, Van Broeckhoven C. Mutated CTSF in adult-onset neuronal ceroid lipofuscinosis and FTD. Neurology. Genetics. 2: e102. PMID 27668283 DOI: 10.1212/Nxg.0000000000000102  0.333
2016 Crosiers D, Verstraeten A, Wauters E, Engelborghs S, Peeters K, Mattheijssens M, De Deyn PP, Theuns J, Van Broeckhoven C, Cras P. Mutations in glucocerebrosidase are a major genetic risk factor for Parkinson's disease and increase susceptibility to dementia in a Flanders-Belgian cohort. Neuroscience Letters. PMID 27397011 DOI: 10.1016/J.Neulet.2016.07.008  0.341
2016 Verheijen J, Van den Bossche T, van der Zee J, Engelborghs S, Sanchez-Valle R, Lladó A, Graff C, Thonberg H, Pastor P, Ortega-Cubero S, Pastor MA, Benussi L, Ghidoni R, Binetti G, Clarimon J, ... ... Cras P, et al. A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer's disease. Acta Neuropathologica. PMID 27026413 DOI: 10.1007/S00401-016-1566-9  0.363
2016 Sieben A, Santens P, Hemelsoet D, Engelborghs S, De Jonghe P, De Bleecker J, Maes J, Jadoul C, Cras P, De Deyn P, Van Broeckhoven C, Martin J. PSP and small vessel disease: more than occasional co-occurence? Neurobiology of Aging. 39: S9-S10. DOI: 10.1016/J.Neurobiolaging.2016.01.050  0.327
2015 Litzroth A, Cras P, De Vil B, Quoilin S. Overview and evaluation of 15 years of Creutzfeldt-Jakob disease surveillance in Belgium, 1998-2012. Bmc Neurology. 15: 250. PMID 26630984 DOI: 10.1186/s12883-015-0507-x  0.318
2015 Cacace R, Van den Bossche T, Engelborghs S, Geerts N, Laureys A, Dillen L, Graff C, Thonberg H, Chiang HH, Pastor P, Ortega-Cubero S, Pastor MA, Diehl-Schmid J, Alexopoulos P, Benussi L, ... ... Cras P, et al. Rare Variants in PLD3 do not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort. Human Mutation. PMID 26411346 DOI: 10.1002/Humu.22908  0.371
2015 Cacace R, Van den Bossche T, Engelborghs S, Vandenbulcke M, Vandenberghe R, De Deyn PP, Cras P, Sleegers K, Van Broeckhoven C. P3-017: Rare variants in PLD3 do not increase risk in a belgian cohort of early-onset Alzheimer dementia patients Alzheimer's & Dementia. 11: P626-P626. DOI: 10.1016/J.Jalz.2015.06.883  0.329
2014 van der Zee J, Van Langenhove T, Kovacs GG, Dillen L, Deschamps W, Engelborghs S, Mat?j R, Vandenbulcke M, Sieben A, Dermaut B, Smets K, Van Damme P, Merlin C, Laureys A, Van Den Broeck M, ... ... Cras P, et al. Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration. Acta Neuropathologica. 128: 397-410. PMID 24899140 DOI: 10.1007/S00401-014-1298-7  0.317
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... ... Cras P, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X  0.317
2014 Cuyvers E, Bettens K, Philtjens S, Van Langenhove T, Gijselinck I, van der Zee J, Engelborghs S, Vandenbulcke M, Van Dongen J, Geerts N, Maes G, Mattheijssens M, Peeters K, Cras P, Vandenberghe R, et al. Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia. Neurobiology of Aging. 35: 726.e11-9. PMID 24119542 DOI: 10.1016/J.Neurobiolaging.2013.09.009  0.389
2014 Cuyvers E, Bettens K, Engelborghs S, Vandenbulcke M, Merlin C, Dillen L, Mattheijssens M, Peeters K, Cras P, Vandenberghe RR, Deyn PD, Zee Jvd, Broeckhoven CV, Sleegers K. Analysis Of Sqstm1 In Patients With Early-Onset Alzheimer'S Disease Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.04.077  0.391
2013 Nalls MA, Duran R, Lopez G, Kurzawa-Akanbi M, McKeith IG, Chinnery PF, Morris CM, Theuns J, Crosiers D, Cras P, Engelborghs S, De Deyn PP, Van Broeckhoven C, Mann DM, Snowden J, et al. A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies. Jama Neurology. 70: 727-35. PMID 23588557 DOI: 10.1001/Jamaneurol.2013.1925  0.329
2013 van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Engelborghs S, Philtjens S, Vandenbulcke M, Sleegers K, Sieben A, Bäumer V, Maes G, Corsmit E, Borroni B, Padovani A, ... ... Cras P, ... ... Cras P, ... ... Cras P, et al. A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats. Human Mutation. 34: 363-73. PMID 23111906 DOI: 10.1002/Humu.22244  0.317
2012 Sieben A, Van Langenhove T, Engelborghs S, Martin JJ, Boon P, Cras P, De Deyn PP, Santens P, Van Broeckhoven C, Cruts M. The genetics and neuropathology of frontotemporal lobar degeneration. Acta Neuropathologica. 124: 353-72. PMID 22890575 DOI: 10.1007/s00401-012-1029-x  0.373
2012 Gijselinck I, Van Langenhove T, van der Zee J, Sleegers K, Philtjens S, Kleinberger G, Janssens J, Bettens K, Van Cauwenberghe C, Pereson S, Engelborghs S, Sieben A, De Jonghe P, Vandenberghe R, Santens P, ... ... Cras P, et al. A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study. The Lancet. Neurology. 11: 54-65. PMID 22154785 DOI: 10.1016/S1474-4422(11)70261-7  0.328
2012 Meeus B, Verstraeten A, Crosiers D, Engelborghs S, Van den Broeck M, Mattheijssens M, Peeters K, Corsmit E, Elinck E, Pickut B, Vandenberghe R, Cras P, De Deyn PP, Van Broeckhoven C, Theuns J. DLB and PDD: a role for mutations in dementia and Parkinson disease genes? Neurobiology of Aging. 33: 629.e5-629.e18. PMID 22118943 DOI: 10.1016/J.Neurobiolaging.2011.10.014  0.36
2011 van der Zee J, Van Langenhove T, Kleinberger G, Sleegers K, Engelborghs S, Vandenberghe R, Santens P, Van den Broeck M, Joris G, Brys J, Mattheijssens M, Peeters K, Cras P, De Deyn PP, Cruts M, et al. TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort. Brain : a Journal of Neurology. 134: 808-15. PMID 21354975 DOI: 10.1093/Brain/Awr007  0.342
2011 Crosiers D, Ceulemans B, Meeus B, Nuytemans K, Pals P, Van Broeckhoven C, Cras P, Theuns J. Juvenile dystonia-parkinsonism and dementia caused by a novel ATP13A2 frameshift mutation. Parkinsonism & Related Disorders. 17: 135-8. PMID 21094623 DOI: 10.1016/j.parkreldis.2010.10.011  0.303
2009 Zerr I, Kallenberg K, Summers DM, Romero C, Taratuto A, Heinemann U, Breithaupt M, Varges D, Meissner B, Ladogana A, Schuur M, Haik S, Collins SJ, Jansen GH, Stokin GB, ... ... Cras P, et al. Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease. Brain : a Journal of Neurology. 132: 2659-68. PMID 19773352 DOI: 10.1093/brain/awp191  0.318
2009 Meissner B, Kallenberg K, Sanchez-Juan P, Collie D, Summers DM, Almonti S, Collins SJ, Smith P, Cras P, Jansen GH, Brandel JP, Coulthart MB, Roberts H, Van Everbroeck B, Galanaud D, et al. MRI lesion profiles in sporadic Creutzfeldt-Jakob disease. Neurology. 72: 1994-2001. PMID 19506221 DOI: 10.1212/WNL.0b013e3181a96e5d  0.324
2008 Nuytemans K, Pals P, Sleegers K, Engelborghs S, Corsmit E, Peeters K, Pickut B, Mattheijssens M, Cras P, De Deyn PP, Theuns J, Van Broeckhoven C. Progranulin variability has no major role in Parkinson disease genetic etiology. Neurology. 71: 1147-51. PMID 18838661 DOI: 10.1212/01.wnl.0000327563.10320.2b  0.391
2008 Haugarvoll K, Rademakers R, Kachergus JM, Nuytemans K, Ross OA, Gibson JM, Tan EK, Gaig C, Tolosa E, Goldwurm S, Guidi M, Riboldazzi G, Brown L, Walter U, Benecke R, ... ... Cras P, et al. Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease. Neurology. 70: 1456-60. PMID 18337586 DOI: 10.1212/01.Wnl.0000304044.22253.03  0.302
2008 Nuytemans K, Rademakers R, Theuns J, Pals P, Engelborghs S, Pickut B, de Pooter T, Peeters K, Mattheijssens M, Van den Broeck M, Cras P, De Deyn PP, van Broeckhoven C. Founder mutation p.R1441C in the leucine-rich repeat kinase 2 gene in Belgian Parkinson's disease patients. European Journal of Human Genetics : Ejhg. 16: 471-9. PMID 18197194 DOI: 10.1038/Sj.Ejhg.5201986  0.321
2008 Engelborghs S, De Vreese K, Van de Casteele T, Vanderstichele H, Van Everbroeck B, Cras P, Martin JJ, Vanmechelen E, De Deyn PP. Diagnostic performance of a CSF-biomarker panel in autopsy-confirmed dementia. Neurobiology of Aging. 29: 1143-59. PMID 17428581 DOI: 10.1016/j.neurobiolaging.2007.02.016  0.364
2007 Brouwers N, Nuytemans K, van der Zee J, Gijselinck I, Engelborghs S, Theuns J, Kumar-Singh S, Pickut BA, Pals P, Dermaut B, Bogaerts V, De Pooter T, Serneels S, Van den Broeck M, Cuijt I, ... ... Cras P, et al. Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. Archives of Neurology. 64: 1436-46. PMID 17923627 DOI: 10.1001/Archneur.64.10.1436  0.363
2007 Abrahantes JC, Aerts M, van Everbroeck B, Saegerman C, Berkvens D, Geys H, Mintiens K, Roels S, Cras P. Classification of sporadic Creutzfeldt-Jakob disease based on clinical and neuropathological characteristics. European Journal of Epidemiology. 22: 457-65. PMID 17587185 DOI: 10.1007/s10654-007-9146-x  0.35
2007 Engelborghs S, Sleegers K, Cras P, Brouwers N, Serneels S, De Leenheir E, Martin JJ, Vanmechelen E, Van Broeckhoven C, De Deyn PP. No association of CSF biomarkers with APOEepsilon4, plaque and tangle burden in definite Alzheimer's disease. Brain : a Journal of Neurology. 130: 2320-6. PMID 17586559 DOI: 10.1093/Brain/Awm136  0.337
2006 Van Everbroeck B, Michotte A, Sciot R, Godfraind C, Deprez M, Quoilin S, Martin JJ, Cras P. Increased incidence of sporadic Creutzfeldt-Jakob disease in the age groups between 70 and 90 years in Belgium. European Journal of Epidemiology. 21: 443-7. PMID 16835721 DOI: 10.1007/s10654-006-9012-2  0.351
2006 van Leeuwen FW, van Tijn P, Sonnemans MA, Hobo B, Mann DM, Van Broeckhoven C, Kumar-Singh S, Cras P, Leuba G, Savioz A, Maat-Schieman ML, Yamaguchi H, Kros JM, Kamphorst W, Hol EM, et al. Frameshift proteins in autosomal dominant forms of Alzheimer disease and other tauopathies. Neurology. 66: S86-92. PMID 16432153 DOI: 10.1212/01.Wnl.0000193882.46003.6D  0.425
2005 Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, et al. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathologica. 110: 232-8. PMID 16096758 DOI: 10.1007/S00401-005-1034-4  0.772
2005 Van Everbroeck B, Boons J, Cras P. Cerebrospinal fluid biomarkers in Creutzfeldt-Jakob disease. Clinical Neurology and Neurosurgery. 107: 355-60. PMID 16023527 DOI: 10.1016/j.clineuro.2004.12.002  0.404
2005 Van Everbroeck BR, Boons J, Cras P. 14-3-3 {gamma}-isoform detection distinguishes sporadic Creutzfeldt-Jakob disease from other dementias. Journal of Neurology, Neurosurgery, and Psychiatry. 76: 100-2. PMID 15608004 DOI: 10.1136/jnnp.2003.032037  0.315
2004 Nunomura A, Chiba S, Lippa CF, Cras P, Kalaria RN, Takeda A, Honda K, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiology of Disease. 17: 108-13. PMID 15350971 DOI: 10.1016/J.Nbd.2004.06.003  0.757
2004 Van Everbroeck B, Dobbeleir I, De Waele M, De Leenheir E, Lübke U, Martin JJ, Cras P. Extracellular protein deposition correlates with glial activation and oxidative stress in Creutzfeldt-Jakob and Alzheimer's disease. Acta Neuropathologica. 108: 194-200. PMID 15221335 DOI: 10.1007/s00401-004-0879-2  0.369
2004 Van Everbroeck B, Boons J, De Leenheir E, Lübke U, Cras P. Molecular diagnostic tools in Creutzfeldt-Jakob disease and other prion disorders. Expert Review of Molecular Diagnostics. 4: 351-9. PMID 15137902 DOI: 10.1586/14737159.4.3.351  0.34
2004 Dermaut B, Kumar-Singh S, Engelborghs S, Theuns J, Rademakers R, Saerens J, Pickut BA, Peeters K, van den Broeck M, Vennekens K, Claes S, Cruts M, Cras P, Martin JJ, Van Broeckhoven C, et al. A novel presenilin 1 mutation associated with Pick's disease but not beta-amyloid plaques. Annals of Neurology. 55: 617-26. PMID 15122701 DOI: 10.1002/Ana.20083  0.355
2004 Van Everbroeck B, Dobbeleir I, De Waele M, De Deyn P, Martin JJ, Cras P. Differential diagnosis of 201 possible Creutzfeldt-Jakob disease patients. Journal of Neurology. 251: 298-304. PMID 15015009 DOI: 10.1007/s00415-004-0311-9  0.388
2003 Van Everbroeck B, Quoilin S, Boons J, Martin JJ, Cras P. A prospective study of CSF markers in 250 patients with possible Creutzfeldt-Jakob disease. Journal of Neurology, Neurosurgery, and Psychiatry. 74: 1210-4. PMID 12933920 DOI: 10.1136/jnnp.74.9.1210  0.409
2003 Spaargaren L, Cras P, Bomhof MA, Lie ST, de Barsy AM, Croese PH, Teepen JL, Duwel VH, Van Goethem JW, Ozsarlak O, van den Hauwe L, De Schepper AM, Parizel PM. Contrast enhancement in Lhermitte-Duclos disease of the cerebellum: correlation of imaging with neuropathology in two cases. Neuroradiology. 45: 381-5. PMID 12750864 DOI: 10.1007/s00234-003-0984-2  0.311
2002 Kumar-Singh S, Cras P, Wang R, Kros JM, van Swieten J, Lübke U, Ceuterick C, Serneels S, Vennekens K, Timmermans JP, Van Marck E, Martin JJ, van Duijn CM, Van Broeckhoven C. Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric. The American Journal of Pathology. 161: 507-20. PMID 12163376 DOI: 10.1016/S0002-9440(10)64207-1  0.398
2002 Van Everbroeck B, Green AJ, Vanmechelen E, Vanderstichele H, Pals P, Sanchez-Valle R, Corrales NC, Martin JJ, Cras P. Phosphorylated tau in cerebrospinal fluid as a marker for Creutzfeldt-Jakob disease. Journal of Neurology, Neurosurgery, and Psychiatry. 73: 79-81. PMID 12082054 DOI: 10.1136/Jnnp.73.1.79  0.364
2002 Van Everbroeck B, Dewulf E, Pals P, Lübke U, Martin JJ, Cras P. The role of cytokines, astrocytes, microglia and apoptosis in Creutzfeldt-Jakob disease. Neurobiology of Aging. 23: 59-64. PMID 11755020 DOI: 10.1016/S0197-4580(01)00236-6  0.371
2001 Cras P. Recent developments in Alzheimer's disease. Acta Clinica Belgica. 56: 269-78. PMID 11770221 DOI: 10.1179/acb.2001.040  0.3
2001 Cataldo A, Rebeck GW, Ghetri B, Hulette C, Lippa C, Van Broeckhoven C, van Duijn C, Cras P, Bogdanovic N, Bird T, Peterhoff C, Nixon R. Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders. Annals of Neurology. 50: 661-5. PMID 11706973 DOI: 10.1002/Ana.1254  0.439
2001 Dermaut B, Kumar-Singh S, De Jonghe C, Cruts M, Löfgren A, Lübke U, Cras P, Dom R, De Deyn PP, Martin JJ, Van Broeckhoven C. Cerebral amyloid angiopathy is a pathogenic lesion in Alzheimer's disease due to a novel presenilin 1 mutation. Brain : a Journal of Neurology. 124: 2383-92. PMID 11701593 DOI: 10.1093/Brain/124.12.2383  0.451
2001 Van Everbroeck B, Croes EA, Pals P, Dermaut B, Jansen G, van Duijn CM, Cruts M, Van Broeckhoven C, Martin JJ, Cras P. Influence of the prion protein and the apolipoprotein E genotype on the Creutzfeldt-Jakob Disease phenotype. Neuroscience Letters. 313: 69-72. PMID 11684342 DOI: 10.1016/S0304-3940(01)02264-9  0.343
2000 Dermaut B, Cruts M, Backhovens H, Lübke U, Van Everbroeck B, Sciot R, Dom R, Martin JJ, Van Broeckhoven C, Cras P. Familial Creutzfeldt-Jakob disease in a patient carrying both a presenilin 1 missense substitution and a prion protein gene insertion. Journal of Neurology. 247: 364-8. PMID 10896268 DOI: 10.1007/S004150050603  0.392
2000 Van Everbroeck B, Pals P, Dziedzic T, Dom R, Godfraind C, Sciot R, Brucher JM, Martin JJ, Cras P. Retrospective study of Creutzfeldt-Jakob disease in Belgium: neuropathological findings. Acta Neuropathologica. 99: 358-64. PMID 10787033 DOI: 10.1007/S004010051136  0.396
2000 Kumar-Singh S, Dewachter I, Moechars D, Lübke U, De Jonghe C, Ceuterick C, Checler F, Naidu A, Cordell B, Cras P, Van Broeckhoven C, Van Leuven F. Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation. Neurobiology of Disease. 7: 9-22. PMID 10671319 DOI: 10.1006/nbdi.1999.0272  0.346
1999 Van Everbroeck B, Green AJ, Pals P, Martin JJ, Cras P. Decreased Levels of Amyloid-beta 1-42 in Cerebrospinal Fluid of Creutzfeldt-Jakob Disease Patients. Journal of Alzheimer's Disease : Jad. 1: 419-424. PMID 12214117 DOI: 10.3233/Jad-1999-1606  0.372
1999 Vanderhoeven I, Cras P, Martin JJ, Van Broeckhoven C, De Jonghe C. Proteolytic processing of presenilin-1 in human lymphoblasts is not affected by the presence of the I143T and G384A mutations. Neuroscience Letters. 274: 183-6. PMID 10548420 DOI: 10.1016/S0304-3940(99)00722-3  0.312
1999 Pals P, Van Everbroeck B, Sciot R, Godfraind C, Robberecht W, Dom R, Laterre C, Martin JJ, Cras P. A retrospective study of Creutzfeldt-Jakob disease in Belgium. European Journal of Epidemiology. 15: 517-9. PMID 10485343 DOI: 10.1023/A:1007581313067  0.356
1999 De Jonghe C, Cras P, Vanderstichele H, Cruts M, Vanderhoeven I, Smouts I, Vanmechelen E, Martin JJ, Hendriks L, Van Broeckhoven C. Evidence that Abeta42 plasma levels in presenilin-1 mutation carriers do not allow for prediction of their clinical phenotype. Neurobiology of Disease. 6: 280-7. PMID 10448055 DOI: 10.1006/nbdi.1999.0247  0.363
1999 Hulstaert F, Blennow K, Ivanoiu A, Schoonderwaldt HC, Riemenschneider M, De Deyn PP, Bancher C, Cras P, Wiltfang J, Mehta PD, Iqbal K, Pottel H, Vanmechelen E, Vanderstichele H. Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF. Neurology. 52: 1555-62. PMID 10331678 DOI: 10.1212/Wnl.52.8.1555  0.355
1998 Cras P, van Harskamp F, Hendriks L, Ceuterick C, van Duijn CM, Stefanko SZ, Hofman A, Kros JM, Van Broeckhoven C, Martin JJ. Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala-->Gly mutation. Acta Neuropathologica. 96: 253-60. PMID 9754958 DOI: 10.1007/s004010050892  0.393
1998 Ceuterick C, Lübke U, Cras P, Martin JJ. Astroglial tangles in the hippocampus of two patients with Down syndrome and Alzheimer neuropathology. Ultrastructural Pathology. 22: 161-3. PMID 9615386 DOI: 10.3109/01913129809032272  0.334
1998 Hendriks L, De Jonghe C, Lübke U, Woodrow S, Vanderhoeven I, Boons J, Cras P, Martin JJ, Van Broeckhoven C. Immunoreactivity of presenilin-1 and tau in Alzheimer's disease brain. Experimental Neurology. 149: 341-8. PMID 9500965 DOI: 10.1006/exnr.1997.6739  0.383
1996 Vamnechelen E, Blennow K, Cras P, Gool WV, Deyn PD, Voorde AVd. 674 Are elevated tau CSF levels in Alzheimer patients related to clinical parameters Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80676-2  0.324
1996 Harskamp Fv, Duyn CMv, Hendriks L, Cras P, Kros JM, Martin JJ, Hofman A, Broeckhoven CHv. 356 Clinical and pathological findings in a family with early onset Alzheimer's disease and cerebral haemorrhage linked to the β-amyloid precursor protein gene Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80358-7  0.38
1996 Voorde AVd, Vanmechelen E, Blennow K, Cras P. 4 Combination of tau/phospho-tau with other biochemical markers to improve the specificity of an Alzheimer's disease test Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80006-6  0.382
1995 Cruts M, Backhovens H, Wang SY, Van Gassen G, Theuns J, De Jonghe CD, Wehnert A, De Voecht J, De Winter G, Cras P. Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3. Human Molecular Genetics. 4: 2363-71. PMID 8634711 DOI: 10.1093/hmg/4.12.2363  0.354
1995 Cras P, Smith MA, Richey PL, Siedlak SL, Mulvihill P, Perry G. Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease. Acta Neuropathologica. 89: 291-5. PMID 7610759 DOI: 10.1007/Bf00309621  0.578
1995 Cras P, Harskamp Fv, Stefanko SZ, Hofman A, Duvn Cv, Broeckhoven CV, Kros JM, Centerick C, Martin JJ. Amyloid Angiopathy Is Associated With A Large Amyloid Core Type Of Senile Plaques In The Amyloid Precursor Protein 692Ala→Gly Mutation: 81 Journal of Neuropathology and Experimental Neurology. 54: 431. DOI: 10.1097/00005072-199505000-00097  0.358
1994 Goedert M, Jakes R, Crowther RA, Cohen P, Vanmechelen E, Vandermeeren M, Cras P. Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein. The Biochemical Journal. 301: 871-7. PMID 7519852 DOI: 10.1042/Bj3010871  0.314
1993 Goedert M, Jakes R, Crowther RA, Six J, Lübke U, Vandermeeren M, Cras P, Trojanowski JQ, Lee VM. The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development. Proceedings of the National Academy of Sciences of the United States of America. 90: 5066-70. PMID 8506352 DOI: 10.1073/Pnas.90.11.5066  0.343
1993 Villanova M, Kawai M, Lübke U, Oh SJ, Perry G, Six J, Ceuterick C, Martin JJ, Cras P. Rimmed vacuoles of inclusion body myositis and oculopharyngeal muscular dystrophy contain amyloid precursor protein and lysosomal markers. Brain Research. 603: 343-7. PMID 8461987 DOI: 10.1016/0006-8993(93)91260-Y  0.586
1993 Vandermeeren M, Mercken M, Vanmechelen E, Six J, van de Voorde A, Martin JJ, Cras P. Detection of tau proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay. Journal of Neurochemistry. 61: 1828-34. PMID 8228996 DOI: 10.1111/J.1471-4159.1993.Tb09823.X  0.397
1993 Kawai M, Kalaria RN, Cras P, Siedlak SL, Velasco ME, Shelton ER, Chan HW, Greenberg BD, Perry G. Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease. Brain Research. 623: 142-6. PMID 8221082 DOI: 10.1016/0006-8993(93)90021-E  0.556
1992 Perry G, Cras P, Siedlak SL, Tabaton M, Kawai M. Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease. The American Journal of Pathology. 140: 283-90. PMID 1739122  0.505
1992 Perry G, Richey P, Siedlak SL, Galloway P, Kawai M, Cras P. Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases. Brain Research. 579: 350-2. PMID 1628222 DOI: 10.1016/0006-8993(92)90074-J  0.758
1992 Kawai M, Cras P, Richey P, Tabaton M, Lowery DE, Gonzalez-DeWhitt PA, Greenberg BD, Gambetti P, Perry G. Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease. The American Journal of Pathology. 140: 947-58. PMID 1562053  0.567
1992 Van Broeckhoven C, Backhovens H, Cruts M, De Winter G, Bruyland M, Cras P, Martin JJ. Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3. Nature Genetics. 2: 335-9. PMID 1303290 DOI: 10.1038/Ng1292-335  0.324
1992 Hendriks L, van Duijn CM, Cras P, Cruts M, Van Hul W, van Harskamp F, Warren A, McInnis MG, Antonarakis SE, Martin JJ. Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene. Nature Genetics. 1: 218-21. PMID 1303239 DOI: 10.1038/Ng0692-218  0.364
1992 Kawai M, Cras P, Perry G. Serial reconstruction of beta-protein amyloid plaques: relationship to microvessels and size distribution. Brain Research. 592: 278-82. PMID 1280517 DOI: 10.1016/0006-8993(92)91686-9  0.599
1991 Martin JJ, Gheuens J, Bruyland M, Cras P, Vandenberghe A, Masters CL, Beyreuther K, Dom R, Ceuterick C, Lübke U. Early-onset Alzheimer's disease in 2 large Belgian families. Neurology. 41: 62-8. PMID 1985297 DOI: 10.1212/Wnl.41.1.62  0.389
1991 Perry G, Siedlak SL, Richey P, Kawai M, Cras P, Kalaria RN, Galloway PG, Scardina JM, Cordell B, Greenberg BD. Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 3679-83. PMID 1941102  0.686
1991 Siedlak SL, Cras P, Kawai M, Richey P, Perry G. Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 39: 899-904. PMID 1865106 DOI: 10.1177/39.7.1865106  0.602
1991 Cras P, Kawai M, Siedlak S, Perry G. Microglia are associated with the extracellular neurofibrillary tangles of Alzheimer disease. Brain Research. 558: 312-4. PMID 1782548 DOI: 10.1016/0006-8993(91)90783-R  0.596
1991 Vande Weghe J, Cras P, Kawai M, Siedlak SL, Tabaton M, Greenberg B, Perry G. Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease. Brain Research. 560: 303-5. PMID 1760735 DOI: 10.1016/0006-8993(91)91247-X  0.685
1991 Cras P, Perry G. Dementia with argyrophilic grains. Annals of Neurology. 30: 853-4. PMID 1724142 DOI: 10.1002/ana.410300621  0.384
1991 Gheuens J, Cras P, Perry G, Boons J, Ceuterick-de Groote C, Lübke U, Mercken M, Tabaton M, Gambetti PL, Vandermeeren M. Demonstration of a novel neurofilament associated antigen with the neurofibrillary pathology of Alzheimer and related diseases. Brain Research. 558: 43-52. PMID 1718569 DOI: 10.1016/0006-8993(91)90712-5  0.646
1991 Cras P, Kawai M, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein. Proceedings of the National Academy of Sciences of the United States of America. 88: 7552-6. PMID 1652752 DOI: 10.1073/Pnas.88.17.7552  0.63
1991 Perry G, Siedlak S, Richey P, Kawai M, Cras P, Kalaria R, Galloway P, Scardina J, Cordell B, Greenberg B. Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease The Journal of Neuroscience. 11: 3679-3683. DOI: 10.1523/Jneurosci.11-11-03679.1991  0.754
1990 Cras P, Gheuens J, Lübke U, Boons J, Vandermeeren M, Van Heuverswijn H, Martin JJ. A monoclonal antibody raised against Alzheimer cortex that specifically recognizes a subpopulation of microglial cells. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 38: 1201-7. PMID 2195115 DOI: 10.1177/38.8.2195115  0.319
1990 Cras P, Kawai M, Siedlak S, Mulvihill P, Gambetti P, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease. The American Journal of Pathology. 137: 241-6. PMID 2117395  0.3
1990 Cras P, Kawai M, Siedlak S, Galloway P, Lowery D, Altman RA, Greenberg B, Perry G. CELLULAR ELEMENTS INVOLVED IN AMYLOID DEPOSITION IN THE SENILE PLAQUE Journal of Neuropathology and Experimental Neurology. 49: 334. DOI: 10.1097/00005072-199005000-00225  0.733
1990 Kawai M, Cras P, Siedlak S, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Shellon E, Gambetli P, Perry G. Role Of Vascular Smooth Muscle Cells In Amyloid Deposition In Cerebral Amyloid Angiopathy: 211 Journal of Neuropathology and Experimental Neurology. 49: 331. DOI: 10.1097/00005072-199005000-00216  0.557
1990 Perry G, Siedlak S, Kawai M, Cras P, Mulvihill P, Cordell B, Scardina JM, Gambetti P. NEUROFIBRILLARY TANGLES, NEUROPIL THREADS AND SENILE PLAQUES ALL CONTAIN ABUNDANT BINDING SITES FOR BASIC FIBROBLAST GROWTH FACTOR (b-FGF) Journal of Neuropathology and Experimental Neurology. 49: 318. DOI: 10.1097/00005072-199005000-00178  0.544
1987 Ebinger G, Bruyland M, Martin JJ, Herregodts P, Cras P, Michotte Y, Gommé L. Distribution of biogenic amines and their catabolites in brains from patients with Alzheimer's disease. Journal of the Neurological Sciences. 77: 267-83. PMID 3819769 DOI: 10.1016/0022-510X(87)90128-6  0.368
1987 Van Broeckhoven C, Genthe AM, Vandenberghe A, Horsthemke B, Backhovens H, Raeymaekers P, Van Hul W, Wehnert A, Gheuens J, Cras P. Failure of familial Alzheimer's disease to segregate with the A4-amyloid gene in several European families. Nature. 329: 153-5. PMID 3306405 DOI: 10.1038/329153A0  0.412
1987 Herregodts P, Cras P, Bruyland M, Michotte Y, Martin JJ, Ebinger G. 57. Degeneration of the serotonergic system in Alzheimer's disease Clinical Neurology and Neurosurgery. 89: 20-21. DOI: 10.1016/0303-8467(87)90057-6  0.385
Show low-probability matches.