Scott J Myers - Publications

Affiliations: 
1999-2008 Pharmacology UNC School of Medicine- Chapel Hill 

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Allen JP, Garber KB, Perszyk R, Khayat CT, Kell SA, Kaneko M, Quindipan C, Saitta S, Ladda RL, Hewson S, Inbar-Feigenberg M, Prasad C, Prasad AN, Olewiler L, Mu W, ... ... Myers SJ, et al. Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants. Human Molecular Genetics. PMID 37944084 DOI: 10.1093/hmg/ddad188  0.563
2023 XiangWei W, Perszyk RE, Liu N, Xu Y, Bhattacharya S, Shaulsky GH, Smith-Hicks C, Fatemi A, Fry AE, Chandler K, Wang T, Vogt J, Cohen JS, Paciorkowski AR, Poduri A, ... ... Myers SJ, et al. Clinical and functional consequences of GRIA variants in patients with neurological diseases. Cellular and Molecular Life Sciences : Cmls. 80: 345. PMID 37921875 DOI: 10.1007/s00018-023-04991-6  0.628
2023 Lewis SA, Shetty S, Gamble S, Heim J, Zhao N, Stitt G, Pankratz M, Mangum T, Marku I, Rosenberg RB, Wilfong AA, Fahey MC, Kim S, Myers SJ, Appavu B, et al. Intrathecal magnesium delivery for Mg++-insensitive NMDA receptor activity due to GRIN1 mutation. Orphanet Journal of Rare Diseases. 18: 225. PMID 37537625 DOI: 10.1186/s13023-023-02756-9  0.363
2023 Myers SJ, Yuan H, Perszyk RE, Zhang J, Kim S, Nocilla KA, Allen JP, Bain JM, Lemke JR, Lal D, Benke TA, Traynelis SF. Classification of missense variants in the N-methyl-D-aspartate receptor GRIN gene family as gain- or loss-of-function. Human Molecular Genetics. PMID 37369021 DOI: 10.1093/hmg/ddad104  0.622
2023 Xie L, McDaniel MJ, Perszyk RE, Kim S, Cappuccio G, Shapiro KA, Muñoz-Cabello B, Sanchez-Lara PA, Grand K, Zhang J, Nocilla KA, Sheikh R, Armengol L, Romano R, Pierson TM, ... ... Myers SJ, et al. Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening. Cellular and Molecular Life Sciences : Cmls. 80: 110. PMID 37000222 DOI: 10.1007/s00018-023-04705-y  0.568
2023 Harris LD, Regan MC, Myers SJ, Nocilla KA, Akins NS, Tahirovic YA, Wilson LJ, Dingledine R, Furukawa H, Traynelis SF, Liotta DC. Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. Acs Chemical Neuroscience. PMID 36779874 DOI: 10.1021/acschemneuro.2c00779  0.639
2023 Tang W, Beckley JT, Zhang J, Song R, Xu Y, Kim S, Quirk MC, Robichaud AJ, Diaz ES, Myers SJ, Doherty JJ, Ackley MA, Traynelis SF, Yuan H. Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions. Cellular and Molecular Life Sciences : Cmls. 80: 42. PMID 36645496 DOI: 10.1007/s00018-022-04667-7  0.718
2022 Strehlow V, Rieubland C, Gallati S, Kim S, Myers SJ, Peterson V, Ramsey AJ, Teuscher DD, Traynelis SF, Lemke JR. Compound-heterozygous GRIN2A null variants associated with severe developmental and epileptic encephalopathy. Epilepsia. PMID 35983985 DOI: 10.1111/epi.17394  0.557
2022 Brock S, Laquerriere A, Marguet F, Myers SJ, Hongjie Y, Baralle D, Vanderhasselt T, Stouffs K, Keymolen K, Kim S, Allen J, Shaulsky G, Chelly J, Marcorelle P, Aziza J, et al. Overlapping cortical malformations in patients with pathogenic variants in and . Journal of Medical Genetics. PMID 35393335 DOI: 10.1136/jmedgenet-2021-107971  0.568
2022 Han W, Yuan H, Allen JP, Kim S, Shaulsky GH, Perszyk RE, Traynelis SF, Myers SJ. . The Journal of Pharmacology and Experimental Therapeutics. PMID 35110392 DOI: 10.1124/jpet.121.001000  0.676
2021 Myers SJ, Ruppa KP, Wilson LJ, Tahirovic YA, Lyuboslavsky P, Menaldino DS, Dentmon ZW, Koszalka GW, Zaczek R, Dingledine RJ, Traynelis SF, Liotta DC. . The Journal of Pharmacology and Experimental Therapeutics. PMID 34493631 DOI: 10.1124/jpet.120.000370  0.594
2021 Zhang J, Tang W, Bhatia NK, Xu Y, Paudyal N, Liu D, Kim S, Song R, XiangWei W, Shaulsky G, Myers SJ, Dobyns W, Jayaraman V, Traynelis SF, Yuan H, et al. A Variant Associated With Myoclonus and Developmental Delay: From Molecular Mechanism to Rescue Pharmacology. Frontiers in Genetics. 12: 694312. PMID 34413877 DOI: 10.3389/fgene.2021.694312  0.611
2020 Amador A, Bostick CD, Olson H, Peters J, Camp CR, Krizay D, Chen W, Han W, Tang W, Kanber A, Kim S, Teoh J, Sah M, Petri S, Paek H, ... ... Myers SJ, et al. Modelling and treating GRIN2A developmental and epileptic encephalopathy in mice. Brain : a Journal of Neurology. PMID 32577763 DOI: 10.1093/Brain/Awaa147  0.611
2020 Perszyk RE, Myers SJ, Yuan H, Gibb AJ, Furukawa H, Sobolevsky AI, Traynelis SF. Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif. The Journal of Physiology. PMID 32468591 DOI: 10.1113/Jp278086  0.629
2020 Zhu Z, Yi F, Epplin MP, Liu D, Summer SL, Mizu R, Shaulsky G, XiangWei W, Tang W, Burger PB, Menaldino DS, Myers SJ, Liotta DC, Hansen KB, Yuan H, et al. Negative allosteric modulation of GluN1/GluN3 NMDA receptors. Neuropharmacology. 108117. PMID 32389749 DOI: 10.1016/J.Neuropharm.2020.108117  0.669
2020 Piard J, Béreau M, XiangWei W, Wirth T, Amsallem D, Buisson L, Richard P, Liu N, Xu Y, Myers SJ, Traynelis SF, Chelly J, Anheim M, Raynaud M, Maldergem LV, et al. The GRIA3 c.2477G > A Variant Causes an Exaggerated Startle Reflex, Chorea, and Multifocal Myoclonus. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32369665 DOI: 10.1002/Mds.28058  0.529
2019 Myers SJ, Yuan H, Kang JQ, Tan FCK, Traynelis SF, Low CM. Distinct roles of and variants in neurological conditions. F1000research. 8. PMID 31807283 DOI: 10.12688/F1000Research.18949.1  0.582
2019 XiangWei W, Kannan V, Xu Y, Kosobucki GJ, Schulien AJ, Kusumoto H, Moufawad El Achkar C, Bhattacharya S, Lesca G, Nguyen S, Helbig KL, Cuisset JM, Fenger CD, Marjanovic D, Schuler E, ... ... Myers SJ, et al. Heterogeneous clinical and functional features of GRIN2D-related developmental and epileptic encephalopathy. Brain : a Journal of Neurology. PMID 31504254 DOI: 10.1093/Brain/Awz232  0.641
2019 Li J, Zhang J, Tang W, Mizu RK, Kusumoto H, XiangWei W, Xu Y, Chen W, Amin JB, Perozo E, Hu C, Kannan V, Keller SR, Wilcox WR, Lemke JR, ... Myers SJ, et al. De Novo GRIN Variants in NMDA Receptor M2 Channel Pore-Forming Loop Are Associated with Neurological Diseases. Human Mutation. PMID 31429998 DOI: 10.1002/Humu.23895  0.646
2019 Summer SL, Kell SA, Zhu Z, Moore R, Liotta DC, Myers SJ, Koszalka GW, Traynelis SF, Menaldino DS. Di-aryl Sulfonamide Motif Adds π-Stacking Bulk in Negative Allosteric Modulators of the NMDA Receptor. Acs Medicinal Chemistry Letters. 10: 248-254. PMID 30891121 DOI: 10.1021/Acsmedchemlett.8B00395  0.636
2019 Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris PJ, Thomas CJ, Zarate CA, et al. Antidepressant-relevant concentrations of the ketamine metabolite (2,6)-hydroxynorketamine do not block NMDA receptor function. Proceedings of the National Academy of Sciences of the United States of America. PMID 30796190 DOI: 10.1073/Pnas.1816071116  0.596
2019 Fu H, Tang W, Chen Z, Belov VV, Zhang G, Shao T, Zhang X, Yu Q, Rong J, Deng X, Han W, Myers S, Giffenig P, Wang L, Josephson L, et al. Synthesis and Preliminary Evaluations of a Triazole-cored Antagonist ([18F]N2B-0518) as PET Imaging Probe for GluN2B Subunit in the Brain. Acs Chemical Neuroscience. PMID 30698943 DOI: 10.1021/Acschemneuro.8B00591  0.51
2019 Regan MC, Zhu Z, Yuan H, Myers SJ, Menaldino DS, Tahirovic YA, Liotta DC, Traynelis SF, Furukawa H. Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors. Nature Communications. 10: 321. PMID 30659174 DOI: 10.2210/Pdb6E7S/Pdb  0.637
2018 Fernández-Marmiesse A, Kusumoto H, Rekarte S, Roca I, Zhang J, Myers SJ, Traynelis SF, Couce ML, Gutierrez-Solana L, Yuan H. A novel missense mutation in GRIN2A causes a nonepileptic neurodevelopmental disorder. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29644724 DOI: 10.1002/Mds.27315  0.587
2017 Swanger SA, Vance KM, Acker TM, Zimmerman SS, DiRaddo JO, Myers SJ, Bundgaard C, Mosley CA, Summer SL, Menaldino DS, Jensen HS, Liotta DC, Traynelis SF. A novel negative allosteric modulator selective for GluN2C/2D-containing NMDA receptors inhibits synaptic transmission in hippocampal interneurons. Acs Chemical Neuroscience. PMID 29043770 DOI: 10.1021/Acschemneuro.7B00329  0.661
2017 Hu C, Chen W, Myers SJ, Yuan H, Traynelis SF. Corrigendum to "Human GRIN2B variants in neurodevelopmental disorders" [J Pharmacol Sci 132 (2) 115-121]. Journal of Pharmacological Sciences. PMID 28434657 DOI: 10.1016/J.Jphs.2017.04.001  0.448
2016 Hu C, Chen W, Myers SJ, Yuan H, Traynelis SF. Human GRIN2B variants in neurodevelopmental disorders. Journal of Pharmacological Sciences. PMID 27818011 DOI: 10.1016/J.Jphs.2016.10.002  0.525
2015 Yuan H, Myers SJ, Wells G, Nicholson KL, Swanger SA, Lyuboslavsky P, Tahirovic YA, Menaldino DS, Ganesh T, Wilson LJ, Liotta DC, Snyder JP, Traynelis SF. Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects. Neuron. 85: 1305-18. PMID 25728572 DOI: 10.1016/J.Neuron.2015.02.008  0.712
2014 Wang H, James ML, Venkatraman TN, Wilson LJ, Lyuboslavsky P, Myers SJ, Lascola CD, Laskowitz DT. pH-sensitive NMDA inhibitors improve outcome in a murine model of SAH. Neurocritical Care. 20: 119-31. PMID 24420693 DOI: 10.1007/s12028-013-9944-9  0.343
2010 Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R. Glutamate receptor ion channels: structure, regulation, and function. Pharmacological Reviews. 62: 405-96. PMID 20716669 DOI: 10.1124/Pr.109.002451  0.76
2009 Mosley CA, Myers SJ, Murray EE, Santangelo R, Tahirovic YA, Kurtkaya N, Mullasseril P, Yuan H, Lyuboslavsky P, Le P, Wilson LJ, Yepes M, Dingledine R, Traynelis SF, Liotta DC. Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors. Bioorganic & Medicinal Chemistry. 17: 6463-80. PMID 19648014 DOI: 10.1016/J.Bmc.2009.05.085  0.739
2008 Tahirovic YA, Geballe M, Gruszecka-Kowalik E, Myers SJ, Lyuboslavsky P, Le P, French A, Irier H, Choi WB, Easterling K, Yuan H, Wilson LJ, Kotloski R, McNamara JO, Dingledine R, et al. Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists. Journal of Medicinal Chemistry. 51: 5506-21. PMID 18800760 DOI: 10.1021/Jm8002153  0.721
2004 Myers SJ, Huang Y, Genetta T, Dingledine R. Inhibition of glutamate receptor 2 translation by a polymorphic repeat sequence in the 5'-untranslated leaders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3489-99. PMID 15071096 DOI: 10.1523/Jneurosci.4127-03.2004  0.685
2003 Borges K, Myers SJ, Zhang S, Dingledine R. Activity of the rat GluR4 promoter in transfected cortical neurons and glia. Journal of Neurochemistry. 86: 1162-73. PMID 12911624 DOI: 10.1046/J.1471-4159.2003.01926.X  0.635
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