Meredith B. Metzger, Ph.D.

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
s.cerevisiae, membrane biology, ABC transporters, protein degradation mechanisms
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"Meredith Metzger"
Mean distance: 21373.2 (cluster 53)
 

Parents

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Susan Michaelis grad student 2009 Johns Hopkins
 (Protein quality control in the endoplasmic reticulum and cytosol.)
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Publications

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Metzger MB, Scales JL, Grant GA, et al. (2023) Differential sensitivity of the yeast Lon protease Pim1p to impaired mitochondrial respiration. The Journal of Biological Chemistry. 104937
Metzger MB, Scales JL, Dunklebarger MF, et al. (2020) A protein quality control pathway at the mitochondrial outer membrane. Elife. 9
Metzger MB, Scales JL, Dunklebarger MF, et al. (2020) Author response: A protein quality control pathway at the mitochondrial outer membrane Elife
Hann ZS, Metzger MB, Weissman AM, et al. (2019) Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7. Acta Crystallographica. Section F, Structural Biology Communications. 75: 552-560
Preston GM, Guerriero CJ, Metzger MB, et al. (2018) Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic-Reticulum-Associated Degradation. Molecular Cell. 70: 242-253.e6
Metzger MB, Scales JL, Dunklebarger MF, et al. (2017) The Ubiquitin Ligase (E3) Psh1p Is Required for Proper Segregation of Both Centromeric and Two Micron Plasmids in Saccharomyces cerevisiae. G3 (Bethesda, Md.)
Li S, Liang YH, Mariano J, et al. (2015) Insights into Ubiquitination from the Unique Clamp-Like Binding of the RING E3 AO7 to the E2 UbcH5B. The Journal of Biological Chemistry
Metzger MB, Pruneda JN, Klevit RE, et al. (2014) RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination. Biochimica Et Biophysica Acta. 1843: 47-60
Metzger MB, Liang YH, Das R, et al. (2013) A structurally unique E2-binding domain activates ubiquitination by the ERAD E2, Ubc7p, through multiple mechanisms. Molecular Cell. 50: 516-27
Metzger MB, Hristova VA, Weissman AM. (2012) HECT and RING finger families of E3 ubiquitin ligases at a glance. Journal of Cell Science. 125: 531-7
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