Thomas Michel - Publications

Affiliations: 
Duke University, Durham, NC 

145 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Spyropoulos F, Das AA, Waldeck-Weiermair M, Yadav S, Pandey AK, Guo R, Covington TA, Thulabandu V, Kosmas K, Steinhorn B, Perella M, Liu X, Christou H, Michel T. Adult and neonatal models of chemogenetic heart failure caused by oxidative stress. The Journal of Clinical Investigation. PMID 38483521 DOI: 10.1172/JCI178251  0.721
2023 Yadav S, Waldeck-Weiermair M, Spyropoulos F, Bronson R, Pandey AK, Das AA, Sisti AC, Covington TA, Thulabandu V, Caplan S, Chutkow W, Steinhorn B, Michel T. Sensory ataxia and cardiac hypertrophy caused by neurovascular oxidative stress in chemogenetic transgenic mouse lines. Nature Communications. 14: 3094. PMID 37248315 DOI: 10.1038/s41467-023-38961-0  0.741
2022 Waldeck-Weiermair M, Yadav S, Kaynert J, Thulabandu VR, Pandey AK, Spyropoulos F, Covington T, Das AA, Krüger C, Michel T. Differential endothelial hydrogen peroxide signaling via Nox isoforms: Critical roles for Rac1 and modulation by statins. Redox Biology. 58: 102539. PMID 36401888 DOI: 10.1016/j.redox.2022.102539  0.352
2022 Spyropoulos F, Sorrentino A, van der Reest J, Yang P, Waldeck-Weiermair M, Steinhorn B, Eroglu E, Saeedi Saravi SS, Yu P, Haigis M, Christou H, Michel T. Metabolomic and Transcriptomic Signatures of Chemogenetic Heart Failure. American Journal of Physiology. Heart and Circulatory Physiology. PMID 35089810 DOI: 10.1152/ajpheart.00628.2021  0.754
2021 Erdogan YC, Altun HY, Secilmis M, Ata BN, Sevimli G, Cokluk Z, Zaki AG, Sezen S, Akgul Caglar T, Sevgen İ, Steinhorn B, Ai H, Öztürk G, Belousov VV, Michel T, et al. Complexities of the chemogenetic toolkit: Differential mDAAO activation by d-amino substrates and subcellular targeting. Free Radical Biology & Medicine. 177: 132-142. PMID 34687864 DOI: 10.1016/j.freeradbiomed.2021.10.023  0.727
2021 Steinhorn B, Eroglu E, Michel T. Chemogenetic Approaches to Probe Redox Pathways: Implications for Cardiovascular Pharmacology and Toxicology. Annual Review of Pharmacology and Toxicology. PMID 34530645 DOI: 10.1146/annurev-pharmtox-012221-082339  0.736
2021 Steinhorn B, Sorrentino A, Badole S, Bogdanova Y, Belousov V, Michel T. Author Correction: Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction. Nature Communications. 12: 357. PMID 33414450 DOI: 10.1038/s41467-020-20668-1  0.728
2021 Spyropoulos F, Sorrentino A, Van Der Reest J, Yang P, Waldeck-Weiermair M, Steinhorn B, Yu P, Haigis M, Christou H, Michel T. TRANSCRIPTOMIC AND METABOLOMIC SIGNATURES OF CHEMOGENETIC HEART FAILURE Journal of the American College of Cardiology. 77: 3401. DOI: 10.1016/S0735-1097(21)04755-0  0.697
2020 Montiel V, Bella R, Michel LYM, Esfahani H, De Mulder D, Robinson EL, Deglasse JP, Tiburcy M, Chow PH, Jonas JC, Gilon P, Steinhorn B, Michel T, Beauloye C, Bertrand L, et al. Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide. Science Translational Medicine. 12. PMID 33028705 DOI: 10.1126/scitranslmed.aay2176  0.79
2020 Saeedi Saravi SS, Eroglu E, Waldeck-Weiermair M, Sorrentino A, Steinhorn B, Belousov V, Michel T. Differential endothelial signaling responses elicited by chemogenetic HO synthesis. Redox Biology. 36: 101605. PMID 32590330 DOI: 10.1016/J.Redox.2020.101605  0.776
2020 Eroglu E, Michel T, Graier WF, Malli R. Yes (again) to local NO. Nature Chemical Biology. 16: 606-607. PMID 32444837 DOI: 10.1038/S41589-020-0552-7  0.318
2020 Sorrentino A, Michel T. Redox à la carte: Novel chemogenetic models of heart failure. British Journal of Pharmacology. PMID 32368791 DOI: 10.1111/Bph.15093  0.392
2020 Pak VV, Ezeriņa D, Lyublinskaya OG, Pedre B, Tyurin-Kuzmin PA, Mishina NM, Thauvin M, Young D, Wahni K, Martínez Gache SA, Demidovich AD, Ermakova YG, Maslova YD, Shokhina AG, Eroglu E, ... ... Michel T, et al. Ultrasensitive Genetically Encoded Indicator for Hydrogen Peroxide Identifies Roles for the Oxidant in Cell Migration and Mitochondrial Function. Cell Metabolism. 31: 642-653.e6. PMID 32130885 DOI: 10.1016/J.Cmet.2020.02.003  0.348
2020 Montiel V, Bella R, Michel L, Robinson E, Jonas J, Michel T, Beauloye C, Bertrand L, Ghigo A, Geninatti-Crich S, Yool A, Zimmermann W, Roderick L, Devuyst O, Balligand J. Inhibition of the water channel aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide European Heart Journal. 41. DOI: 10.1093/ehjci/ehaa946.3665  0.589
2019 Eroglu E, Saravi SSS, Sorrentino A, Steinhorn B, Michel T. Discordance between eNOS phosphorylation and activation revealed by multispectral imaging and chemogenetic methods. Proceedings of the National Academy of Sciences of the United States of America. PMID 31527268 DOI: 10.1073/Pnas.1910942116  0.765
2019 Sorrentino A, Steinhorn B, Troncone L, Saravi SS, Badole SL, Eroglu E, Kijewski MF, Divakaran S, Di Carli M, Michel T. Reversal of heart failure in a chemogenetic model of persistent cardiac redox stress. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31298558 DOI: 10.1152/Ajpheart.00177.2019  0.755
2019 Mishina NM, Bogdanova YA, Ermakova YG, Panova AS, Kotova DA, Bilan D, Steinhorn B, Arnér ESJ, Michel T, Belousov V. Which antioxidant system shapes intracellular H2O2 gradients? Antioxidants & Redox Signaling. PMID 30864831 DOI: 10.1089/Ars.2018.7697  0.733
2018 Steinhorn B, Sorrentino A, Badole S, Bogdanova Y, Belousov V, Michel T. Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction. Nature Communications. 9: 4044. PMID 30279532 DOI: 10.1038/S41467-018-06533-2  0.764
2018 Montiel V, Esfahani H, Mulder DD, Deglasse JP, Jonas JC, Steinhorn B, Michel T, Devuyst O, Balligand JL. 35Cardiac aquaporin-1 mediates transmembrane transport of hydrogen peroxide and modulates myocardial fibrosis and hypertrophic remodeling Cardiovascular Research. 114. DOI: 10.1093/Cvr/Cvy060.015  0.763
2018 Michel T. Regulation of nitric oxide synthases by intracellular oxidants Free Radical Biology and Medicine. 120. DOI: 10.1016/J.Freeradbiomed.2018.04.057  0.469
2017 Steinhorn B, Sartoretto JL, Sorrentino A, Romero N, Kalwa H, Dale Abel E, Michel T. Insulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH-oxidase isoforms NOX2 and NOX4. Free Radical Biology & Medicine. PMID 28917508 DOI: 10.1016/J.Freeradbiomed.2017.09.006  0.731
2017 Lamas S, Michel T. Introduction to Special Issue "Redox regulation of cardiovascular signaling in health and disease". Free Radical Biology & Medicine. PMID 28450147 DOI: 10.1016/J.Freeradbiomed.2017.04.030  0.545
2017 Michel T. Localized hydrogen peroxide metabolism and cardiovascular signal transduction Free Radical Biology and Medicine. 108. DOI: 10.1016/J.Freeradbiomed.2017.04.058  0.422
2016 Kinlay S, Michel T, Leopold JA. The Future of Vascular Biology and Medicine. Circulation. 133: 2603-9. PMID 27324355 DOI: 10.1161/Circulationaha.116.023513  0.356
2016 Goettsch C, Hutcheson JD, Aikawa M, Iwata H, Pham T, Nykjaer A, Kjolby M, Rogers M, Michel T, Shibasaki M, Hagita S, Kramann R, Rader DJ, Libby P, Singh SA, et al. Sortilin mediates vascular calcification via its recruitment into extracellular vesicles. The Journal of Clinical Investigation. PMID 26950419 DOI: 10.1172/Jci80851  0.353
2016 Machlus KR, Wu SK, Stumpo DJ, Soussou TS, Paul DS, Campbell RA, Kalwa H, Michel T, Bergmeier W, Weyrich AS, Blackshear PJ, Hartwig JH, Italiano JE. Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation. Blood. PMID 26744461 DOI: 10.1182/Blood-2015-08-663146  0.335
2015 Wang L, Hagemann TL, Kalwa H, Michel T, Messing A, Feany MB. Nitric oxide mediates glial-induced neurodegeneration in Alexander disease. Nature Communications. 6: 8966. PMID 26608817 DOI: 10.1038/Ncomms9966  0.328
2015 Steinhorn BS, Loscalzo J, Michel T. Nitroglycerin and Nitric Oxide--A Rondo of Themes in Cardiovascular Therapeutics. The New England Journal of Medicine. 373: 277-80. PMID 26176386 DOI: 10.1056/Nejmsr1503311  0.748
2015 Tarrago L, Péterfi Z, Lee BC, Michel T, Gladyshev VN. Monitoring methionine sulfoxide with stereospecific mechanism-based fluorescent sensors. Nature Chemical Biology. 11: 332-8. PMID 25799144 DOI: 10.1038/Nchembio.1787  0.301
2014 Barroso M, Florindo C, Kalwa H, Silva Z, Turanov AA, Carlson BA, de Almeida IT, Blom HJ, Gladyshev VN, Hatfield DL, Michel T, Castro R, Loscalzo J, Handy DE. Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression. The Journal of Biological Chemistry. 289: 15350-62. PMID 24719327 DOI: 10.1074/Jbc.M114.549782  0.422
2014 Kalwa H, Sartoretto JL, Martinelli R, Romero N, Steinhorn BS, Tao M, Ozaki CK, Carman CV, Michel T. Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium. Proceedings of the National Academy of Sciences of the United States of America. 111: 3383-8. PMID 24550450 DOI: 10.1073/Pnas.1320854111  0.766
2014 Sawada N, Jiang A, Takizawa F, Safdar A, Manika A, Tesmenitsky Y, Kang KT, Bischoff J, Kalwa H, Sartoretto JL, Kamei Y, Benjamin LE, Watada H, Ogawa Y, Higashikuni Y, ... ... Michel T, et al. Endothelial PGC-1α mediates vascular dysfunction in diabetes. Cell Metabolism. 19: 246-58. PMID 24506866 DOI: 10.1016/J.Cmet.2013.12.014  0.338
2014 Shiroto T, Romero N, Sugiyama T, Sartoretto JL, Kalwa H, Yan Z, Shimokawa H, Michel T. Caveolin-1 is a critical determinant of autophagy, metabolic switching, and oxidative stress in vascular endothelium. Plos One. 9: e87871. PMID 24498385 DOI: 10.1371/Journal.Pone.0087871  0.401
2013 Michel T. R is for arginine: metabolism of arginine takes off again, in new directions. Circulation. 128: 1400-4. PMID 24004503 DOI: 10.1161/Circulationaha.113.005924  0.31
2013 Sartoretto JL, Kalwa H, Romero N, Michel T. In vivo imaging of nitric oxide and hydrogen peroxide in cardiac myocytes. Methods in Enzymology. 528: 61-78. PMID 23849859 DOI: 10.1016/B978-0-12-405881-1.00004-5  0.448
2013 Bretón-Romero R, Kalwa H, Lamas S, Michel T. Role of PTEN in modulation of ADP-dependent signaling pathways in vascular endothelial cells. Biochimica Et Biophysica Acta. 1833: 2586-2595. PMID 23806663 DOI: 10.1016/J.Bbamcr.2013.06.009  0.649
2013 Tatematsu S, Francis SA, Natarajan P, Rader DJ, Saghatelian A, Brown JD, Michel T, Plutzky J. Endothelial lipase is a critical determinant of high-density lipoprotein-stimulated sphingosine 1-phosphate-dependent signaling in vascular endothelium. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1788-94. PMID 23723371 DOI: 10.1161/Atvbaha.113.301300  0.372
2013 Romero N, Shiroto T, Kalwa H, Sartoretto J, Sugiyama T, Michel T. Caveolin-1 is a Critical Determinant of Autophagy and Oxidative Stress Free Radical Biology and Medicine. 65. DOI: 10.1016/J.Freeradbiomed.2013.10.589  0.333
2012 Maron BA, Michel T. Subcellular localization of oxidants and redox modulation of endothelial nitric oxide synthase. Circulation Journal : Official Journal of the Japanese Circulation Society. 76: 2497-512. PMID 23075817 DOI: 10.1253/Circj.Cj-12-1207  0.473
2012 Sartoretto JL, Kalwa H, Shiroto T, Sartoretto SM, Pluth MD, Lippard SJ, Michel T. Role of Ca2+ in the control of H2O2-modulated phosphorylation pathways leading to eNOS activation in cardiac myocytes. Plos One. 7: e44627. PMID 22970272 DOI: 10.1371/Journal.Pone.0044627  0.354
2012 Jin BY, Lin AJ, Golan DE, Michel T. MARCKS protein mediates hydrogen peroxide regulation of endothelial permeability. Proceedings of the National Academy of Sciences of the United States of America. 109: 14864-9. PMID 22927426 DOI: 10.1073/Pnas.1204974109  0.409
2012 Kalwa H, Sartoretto JL, Sartoretto SM, Michel T. Angiotensin-II and MARCKS: a hydrogen peroxide- and RAC1-dependent signaling pathway in vascular endothelium. The Journal of Biological Chemistry. 287: 29147-58. PMID 22773836 DOI: 10.1074/Jbc.M112.381517  0.347
2012 Kou R, Shiroto T, Sartoretto JL, Michel T. Suppression of Gαs synthesis by simvastatin treatment of vascular endothelial cells. The Journal of Biological Chemistry. 287: 2643-51. PMID 22144680 DOI: 10.1074/Jbc.M111.303594  0.396
2012 Sartoretto J, Kalwa H, Michel T. Hydrogen peroxide and differential activation of nitric oxide synthases in cardiac myocytes Free Radical Biology and Medicine. 53. DOI: 10.1016/J.Freeradbiomed.2012.08.115  0.417
2011 Sartoretto JL, Kalwa H, Pluth MD, Lippard SJ, Michel T. Hydrogen peroxide differentially modulates cardiac myocyte nitric oxide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 15792-7. PMID 21896719 DOI: 10.1073/Pnas.1111331108  0.424
2011 Kalwa H, Michel T. The MARCKS protein plays a critical role in phosphatidylinositol 4,5-bisphosphate metabolism and directed cell movement in vascular endothelial cells. The Journal of Biological Chemistry. 286: 2320-30. PMID 21097841 DOI: 10.1074/Jbc.M110.196022  0.37
2010 Michel T. NO way to relax: the complexities of coupling nitric oxide synthase pathways in the heart. Circulation. 121: 484-6. PMID 20083685 DOI: 10.1161/Cir.0B013E3181D1E24E  0.456
2010 Michel T, Vanhoutte PM. Cellular signaling and NO production. Pflugers Archiv : European Journal of Physiology. 459: 807-16. PMID 20082095 DOI: 10.1007/S00424-009-0765-9  0.403
2010 Sugiyama T, Michel T. Thiol-metabolizing proteins and endothelial redox state: differential modulation of eNOS and biopterin pathways. American Journal of Physiology. Heart and Circulatory Physiology. 298: H194-201. PMID 19897710 DOI: 10.1152/Ajpheart.00767.2009  0.345
2009 Jin BY, Sartoretto JL, Gladyshev VN, Michel T. Endothelial nitric oxide synthase negatively regulates hydrogen peroxide-stimulated AMP-activated protein kinase in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 17343-8. PMID 19805165 DOI: 10.1073/Pnas.0907409106  0.39
2009 Hess CN, Kou R, Johnson RP, Li GK, Michel T. ADP signaling in vascular endothelial cells: ADP-dependent activation of the endothelial isoform of nitric-oxide synthase requires the expression but not the kinase activity of AMP-activated protein kinase. The Journal of Biological Chemistry. 284: 32209-24. PMID 19783664 DOI: 10.1074/Jbc.M109.032656  0.411
2009 Sartoretto JL, Jin BY, Bauer M, Gertler FB, Liao R, Michel T. Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1697-710. PMID 19734360 DOI: 10.1152/Ajpheart.00595.2009  0.412
2009 Kou R, Sartoretto J, Michel T. Regulation of Rac1 by simvastatin in endothelial cells: differential roles of AMP-activated protein kinase and calmodulin-dependent kinase kinase-beta. The Journal of Biological Chemistry. 284: 14734-43. PMID 19332549 DOI: 10.1074/Jbc.M808664200  0.37
2009 Sugiyama T, Levy BD, Michel T. Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells. The Journal of Biological Chemistry. 284: 12691-700. PMID 19286667 DOI: 10.1074/Jbc.M809295200  0.455
2009 Igarashi J, Michel T. Sphingosine-1-phosphate and modulation of vascular tone. Cardiovascular Research. 82: 212-20. PMID 19233865 DOI: 10.1093/Cvr/Cvp064  0.368
2009 Kanda T, Brown JD, Orasanu G, Vogel S, Gonzalez FJ, Sartoretto J, Michel T, Plutzky J. PPARgamma in the endothelium regulates metabolic responses to high-fat diet in mice. The Journal of Clinical Investigation. 119: 110-24. PMID 19065047 DOI: 10.1172/Jci36233  0.315
2009 Michel T. Nitric oxide synthase 3 Afcs-Nature Molecule Pages. DOI: 10.1038/Mp.A001660.01  0.375
2008 Igarashi J, Michel T. S1P and eNOS regulation. Biochimica Et Biophysica Acta. 1781: 489-95. PMID 18638569 DOI: 10.1016/J.Bbalip.2008.06.008  0.418
2008 Igarashi J, Michel T. The enigma of sphingosine 1-phosphate synthesis: a novel role for endothelial sphingosine kinases. Circulation Research. 102: 630-2. PMID 18369161 DOI: 10.1161/Circresaha.108.173799  0.368
2008 Chen H, Levine YC, Golan DE, Michel T, Lin AJ. Atrial natriuretic peptide-initiated cGMP pathways regulate vasodilator-stimulated phosphoprotein phosphorylation and angiogenesis in vascular endothelium. The Journal of Biological Chemistry. 283: 4439-47. PMID 18079117 DOI: 10.1074/Jbc.M709439200  0.436
2007 Kou R, Michel T. Epinephrine regulation of the endothelial nitric-oxide synthase: roles of RAC1 and beta3-adrenergic receptors in endothelial NO signaling. The Journal of Biological Chemistry. 282: 32719-29. PMID 17855349 DOI: 10.1074/Jbc.M706815200  0.449
2007 Lamas S, Lowenstein CJ, Michel T. Nitric oxide signaling comes of age: 20 years and thriving. Cardiovascular Research. 75: 207-9. PMID 17574221 DOI: 10.1016/J.Cardiores.2007.05.023  0.626
2007 Atochin DN, Wang A, Liu VW, Critchlow JD, Dantas AP, Looft-Wilson R, Murata T, Salomone S, Shin HK, Ayata C, Moskowitz MA, Michel T, Sessa WC, Huang PL. The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. The Journal of Clinical Investigation. 117: 1961-7. PMID 17557122 DOI: 10.1172/Jci29877  0.326
2007 Levine YC, Li GK, Michel T. Agonist-modulated regulation of AMP-activated protein kinase (AMPK) in endothelial cells. Evidence for an AMPK -> Rac1 -> Akt -> endothelial nitric-oxide synthase pathway. The Journal of Biological Chemistry. 282: 20351-64. PMID 17519230 DOI: 10.1074/Jbc.M702182200  0.422
2007 Dudzinski DM, Michel T. Life history of eNOS: partners and pathways. Cardiovascular Research. 75: 247-60. PMID 17466957 DOI: 10.1016/J.Cardiores.2007.03.023  0.396
2006 Lowenstein CJ, Michel T. What's in a name? eNOS and anaphylactic shock. The Journal of Clinical Investigation. 116: 2075-8. PMID 16886052 DOI: 10.1172/Jci29406  0.395
2006 Chen H, Michel T. Insulin signaling in vascular endothelial cells: a key role for heterotrimeric G proteins revealed by siRNA-mediated Gbeta1 knockdown. Biochemistry. 45: 8023-33. PMID 16800627 DOI: 10.1021/Bi0600906  0.356
2006 Dudzinski DM, Igarashi J, Greif D, Michel T. The regulation and pharmacology of endothelial nitric oxide synthase. Annual Review of Pharmacology and Toxicology. 46: 235-76. PMID 16402905 DOI: 10.1146/Annurev.Pharmtox.44.101802.121844  0.432
2006 Gonzalez E, Kou R, Michel T. Rac1 modulates sphingosine 1-phosphate-mediated activation of phosphoinositide 3-kinase/Akt signaling pathways in vascular endothelial cells. The Journal of Biological Chemistry. 281: 3210-6. PMID 16339142 DOI: 10.1074/Jbc.M510434200  0.4
2006 Erwin PA, Mitchell DA, Sartoretto J, Marletta MA, Michel T. Subcellular targeting and differential S-nitrosylation of endothelial nitric-oxide synthase. The Journal of Biological Chemistry. 281: 151-7. PMID 16286475 DOI: 10.1074/Jbc.M510421200  0.38
2005 Kou R, SenBanerjee S, Jain MK, Michel T. Differential regulation of vascular endothelial growth factor receptors (VEGFR) revealed by RNA interference: interactions of VEGFR-1 and VEGFR-2 in endothelial cell signaling. Biochemistry. 44: 15064-73. PMID 16274253 DOI: 10.1021/Bi0509898  0.401
2005 Mitchell DA, Erwin PA, Michel T, Marletta MA. S-Nitrosation and regulation of inducible nitric oxide synthase. Biochemistry. 44: 4636-47. PMID 15779890 DOI: 10.1021/Bi0474463  0.306
2005 Erwin PA, Lin AJ, Golan DE, Michel T. Receptor-regulated dynamic S-nitrosylation of endothelial nitric-oxide synthase in vascular endothelial cells. The Journal of Biological Chemistry. 280: 19888-94. PMID 15774480 DOI: 10.1074/Jbc.M413058200  0.439
2004 Gonzalez E, Nagiel A, Lin AJ, Golan DE, Michel T. Small interfering RNA-mediated down-regulation of caveolin-1 differentially modulates signaling pathways in endothelial cells. The Journal of Biological Chemistry. 279: 40659-69. PMID 15292187 DOI: 10.1074/Jbc.M407051200  0.432
2004 Greif DM, Sacks DB, Michel T. Calmodulin phosphorylation and modulation of endothelial nitric oxide synthase catalysis Proceedings of the National Academy of Sciences of the United States of America. 101: 1165-1170. PMID 14736917 DOI: 10.1073/Pnas.0306377101  0.375
2003 Jobin CM, Chen H, Lin AJ, Yacono PW, Igarashi J, Michel T, Golan DE. Receptor-regulated dynamic interaction between endothelial nitric oxide synthase and calmodulin revealed by fluorescence resonance energy transfer in living cells. Biochemistry. 42: 11716-25. PMID 14529282 DOI: 10.1021/Bi035066W  0.405
2003 Igarashi J, Erwin PA, Dantas AP, Chen H, Michel T. VEGF induces S1P1 receptors in endothelial cells: Implications for cross-talk between sphingolipid and growth factor receptors. Proceedings of the National Academy of Sciences of the United States of America. 100: 10664-9. PMID 12963813 DOI: 10.1073/Pnas.1934494100  0.38
2003 Dantas APV, Igarashi J, Michel T. Sphingosine 1-phosphate and control of vascular tone American Journal of Physiology-Heart and Circulatory Physiology. 284. PMID 12742827 DOI: 10.1152/Ajpheart.01089.2002  0.404
2003 Thatte HS, Biswas KS, Najjar SF, Birjiniuk V, Crittenden MD, Michel T, Khuri SF. Multi-photon microscopic evaluation of saphenous vein endothelium and its preservation with a new solution, GALA The Annals of Thoracic Surgery. 75: 1145-1152. PMID 12683553 DOI: 10.1016/S0003-4975(02)04705-7  0.313
2002 Greif DM, Kou R, Michel T. Site-specific dephosphorylation of endothelial nitric oxide synthase by protein phosphatase 2A: evidence for crosstalk between phosphorylation sites. Biochemistry. 41: 15845-15853. PMID 12501214 DOI: 10.1021/Bi026732G  0.426
2002 Gonzalez E, Kou R, Lin AJ, Golan DE, Michel T. Subcellular targeting and agonist-induced site-specific phosphorylation of endothelial nitric-oxide synthase. The Journal of Biological Chemistry. 277: 39554-60. PMID 12189156 DOI: 10.1074/Jbc.M207299200  0.404
2002 Kou R, Greif D, Michel T. Dephosphorylation of endothelial nitric-oxide synthase by vascular endothelial growth factor. Implications for the vascular responses to cyclosporin A. Journal of Biological Chemistry. 277: 29669-29673. PMID 12050171 DOI: 10.1074/Jbc.M204519200  0.427
2002 Kou R, Igarashi J, Michel T. Lysophosphatidic acid and receptor-mediated activation of endothelial nitric-oxide synthase. Biochemistry. 41: 4982-4988. PMID 11939794 DOI: 10.1021/Bi016017R  0.443
2001 Igarashi J, Michel T. Sphingosine 1-phosphate and isoform-specific activation of phosphoinositide 3-kinase β: evidence for divergence and convergence of receptor-regulated eNOS signaling pathways Journal of Biological Chemistry. 276: 36281-8. PMID 11470796 DOI: 10.1074/Jbc.M105628200  0.406
2001 Trimmer BA, Aprille JR, Dudzinski DM, Lagace CJ, Lewis SM, Michel T, Qazi S, Zayas RM. Nitric oxide and the control of firefly flashing. Science (New York, N.Y.). 292: 2486-8. PMID 11431567 DOI: 10.1126/Science.1059833  0.336
2001 Navarro-Antolín J, López-Muñoz MJ, Klatt P, Soria J, Michel T, Lamas S. Formation of peroxynitrite in vascular endothelial cells exposed to cyclosporine A. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1291-3. PMID 11344117 DOI: 10.1096/Fj.00-0636Fje  0.604
2001 Igarashi J, Bernier SG, Michel T. Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. Differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells Journal of Biological Chemistry. 276: 12420-12426. PMID 11278407 DOI: 10.1074/Jbc.M008375200  0.42
2001 Biswas KS, Thatte HS, Najjar SF, Rhee JH, Birjiniuk V, Crittenden MD, Michel T, Khuri SF. Multi-photon microscopy in the evaluation of human saphenous vein Journal of Surgical Research. 95: 37-43. PMID 11120633 DOI: 10.1006/Jsre.2000.6019  0.34
2000 Igarashi J, Michel T. Agonist-modulated targeting of the EDG-1 receptor to plasmalemmal caveolae. eNOS activation by sphingosine 1-phosphate and the role of caveolin-1 in sphingolipid signal transduction. Journal of Biological Chemistry. 275: 32363-32370. PMID 10921915 DOI: 10.1074/Jbc.M003075200  0.418
2000 Bernier SG, Haldar S, Michel T. Bradykinin-regulated interactions of the mitogen-activated protein kinase pathway with the endothelial nitric-oxide synthase Journal of Biological Chemistry. 275: 30707-30715. PMID 10899167 DOI: 10.1074/Jbc.M005116200  0.368
2000 Kubota I, Han X, Opel DJ, Zhao YY, Baliga R, Huang P, Fishman MC, Shannon RP, Michel T, Kelly RA. Increased susceptibility to development of triggered activity in myocytes from mice with targeted disruption of endothelial nitric oxide synthase. Journal of Molecular and Cellular Cardiology. 32: 1239-48. PMID 10860766 DOI: 10.1006/Jmcc.2000.1158  0.469
1999 Michel T. Targeting and translocation of endothelial nitric oxide synthase Brazilian Journal of Medical and Biological Research. 32: 1361-1366. PMID 10559837 DOI: 10.1590/S0100-879X1999001100006  0.463
1999 Yeh DC, Duncan JA, Yamashita S, Michel T. Depalmitoylation of endothelial nitric-oxide synthase by acyl-protein thioesterase 1 is potentiated by Ca2+-calmodulin Journal of Biological Chemistry. 274: 33148-33154. PMID 10551886 DOI: 10.1074/jbc.274.46.33148  0.326
1999 Igarashi J, Thatte HS, Prabhakar P, Golan DE, Michel T. Calcium-independent activation of endothelial nitric oxide synthase by ceramide. Proceedings of the National Academy of Sciences of the United States of America. 96: 12583-8. PMID 10535965 DOI: 10.1073/Pnas.96.22.12583  0.406
1999 Goetz RM, Thatte HS, Prabhakar P, Cho MR, Michel T, Golan DE. Estradiol induces the calcium-dependent translocation of endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 96: 2788-93. PMID 10077589 DOI: 10.1073/Pnas.96.6.2788  0.429
1998 Teng BQ, Murthy KS, Kuemmerle JF, Grider JR, Sase K, Michel T, Makhlouf GM. Expression of endothelial nitric oxide synthase in human and rabbit gastrointestinal smooth muscle cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 275: G342-G351. PMID 29585533 DOI: 10.1152/Ajpgi.1998.275.2.G342  0.35
1998 Feron O, Dessy C, Opel DJ, Arstall MA, Kelly RA, Michel T. Modulation of the endothelial nitric-oxide synthase-caveolin interaction in cardiac myocytes. Implications for the autonomic regulation of heart rate. The Journal of Biological Chemistry. 273: 30249-54. PMID 9804784 DOI: 10.1074/Jbc.273.46.30249  0.642
1998 Prabhakar P, Thatte HS, Goetz RM, Cho MR, Golan DE, Michel T. Receptor-regulated translocation of endothelial nitric-oxide synthase. The Journal of Biological Chemistry. 273: 27383-8. PMID 9765266 DOI: 10.1074/Jbc.273.42.27383  0.414
1998 Han X, Kubota I, Feron O, Opel DJ, Arstall MA, Zhao YY, Huang P, Fishman MC, Michel T, Kelly RA. Muscarinic cholinergic regulation of cardiac myocyte ICa-L is absent in mice with targeted disruption of endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 95: 6510-5. PMID 9600997 DOI: 10.1073/Pnas.95.11.6510  0.605
1998 Feron O, Saldana F, Michel JB, Michel T. The endothelial nitric-oxide synthase-caveolin regulatory cycle. The Journal of Biological Chemistry. 273: 3125-8. PMID 9452418 DOI: 10.1074/Jbc.273.6.3125  0.594
1998 Feron O, Michel JB, Sase K, Michel T. Dynamic regulation of endothelial nitric oxide synthase: complementary roles of dual acylation and caveolin interactions. Biochemistry. 37: 193-200. PMID 9425039 DOI: 10.1021/Bi972307P  0.597
1998 German Z, Pace MC, Michel T, Lowenstein CJ, Shaul PW. Molecular Basis of Cell-Specific Endothelial Nitric Oxide Synthase Expression in Airway Epithelium |[bull]| 263 Pediatric Research. 43: 47-47. DOI: 10.1203/00006450-199804001-00284  0.375
1997 Sase K, Michel T. Expression and Regulation of Endothelial Nitric Oxide Synthase Trends in Cardiovascular Medicine. 7: 28-37. PMID 21235861 DOI: 10.1016/S1050-1738(96)00121-1  0.456
1997 Michel T, Feron O. Nitric oxide synthases: which, where, how, and why? The Journal of Clinical Investigation. 100: 2146-52. PMID 9410890 DOI: 10.1172/Jci119750  0.567
1997 Michel JB, Feron O, Sase K, Prabhakar P, Michel T. Caveolin versus calmodulin. Counterbalancing allosteric modulators of endothelial nitric oxide synthase. The Journal of Biological Chemistry. 272: 25907-12. PMID 9325323 DOI: 10.1074/Jbc.272.41.25907  0.594
1997 Feron O, Smith TW, Michel T, Kelly RA. Dynamic targeting of the agonist-stimulated m2 muscarinic acetylcholine receptor to caveolae in cardiac myocytes. The Journal of Biological Chemistry. 272: 17744-8. PMID 9211926 DOI: 10.1074/Jbc.272.28.17744  0.57
1997 Michel JB, Feron O, Sacks D, Michel T. Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin. The Journal of Biological Chemistry. 272: 15583-6. PMID 9188442 DOI: 10.1074/Jbc.272.25.15583  0.597
1997 Belhassen L, Feron O, Kaye DM, Michel T, Kelly RA. Regulation by cAMP of post-translational processing and subcellular targeting of endothelial nitric-oxide synthase (type 3) in cardiac myocytes. The Journal of Biological Chemistry. 272: 11198-204. PMID 9111020 DOI: 10.1074/Jbc.272.17.11198  0.627
1997 Michel JB, Michel T. The role of palmitoyl–protein thioesterase in the palmitoylation of endothelial nitric oxide synthase Febs Letters. 405: 356-362. PMID 9108318 DOI: 10.1016/S0014-5793(97)00222-6  0.418
1996 Smith TW, Balligand JL, Kaye DM, Wiviott SD, Simmons WW, Han X, Michel T, Singh K, Kelly RA. The role of the NO pathway in the control of cardiac function. Journal of Cardiac Failure. 2: S141-7. PMID 8951572 DOI: 10.1016/S1071-9164(96)80070-4  0.66
1996 Feron O, Belhassen L, Kobzik L, Smith TW, Kelly RA, Michel T. Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells. The Journal of Biological Chemistry. 271: 22810-4. PMID 8798458 DOI: 10.1074/Jbc.271.37.22810  0.627
1996 Robinson LJ, Michel T. Endothelial nitric oxide synthase expression in heterologous systems. Methods in Enzymology. 269: 55-64. PMID 8791637 DOI: 10.1016/S0076-6879(96)69009-0  0.352
1996 Robinson LJ, Ghanouni P, Michel T. Posttranslational modifications of endothelial nitric oxide synthase. Methods in Enzymology. 268: 436-48. PMID 8782610 DOI: 10.1016/S0076-6879(96)68046-X  0.414
1996 Buttery LD, Chester AH, Springall DR, Borland JA, Michel T, Yacoub MH, Polak JM. Explanted vein grafts with an intact endothelium demonstrate reduced focal expression of endothelial nitric oxide synthase specific to atherosclerotic sites. The Journal of Pathology. 179: 197-203. PMID 8758213 DOI: 10.1002/(Sici)1096-9896(199606)179:2<197::Aid-Path587>3.0.Co;2-D  0.337
1996 Shaul PW, Smart EJ, Robinson LJ, German Z, Yuhanna IS, Ying Y, Anderson RGW, Michel T. Acylation targets endothelial nitric-oxide synthase to plasmalemmal caveolae Journal of Biological Chemistry. 271: 6518-6522. PMID 8626455 DOI: 10.1074/Jbc.271.11.6518  0.365
1995 Robinson LJ, Michel T. Mutagenesis of palmitoylation sites in endothelial nitric oxide synthase identifies a novel motif for dual acylation and subcellular targeting Proceedings of the National Academy of Sciences of the United States of America. 92: 11776-11780. PMID 8524847 DOI: 10.1073/Pnas.92.25.11776  0.373
1995 Ungureanu-Longrois D, Balligand JL, Simmons WW, Okada I, Kobzik L, Lowenstein CJ, Kunkel SL, Michel T, Kelly RA, Smith TW. Induction of nitric oxide synthase activity by cytokines in ventricular myocytes is necessary but not sufficient to decrease contractile responsiveness to beta-adrenergic agonists. Circulation Research. 77: 494-502. PMID 7543826 DOI: 10.1161/01.Res.77.3.494  0.58
1995 Ungureanu-Longrois D, Balligand JL, Okada I, Simmons WW, Kobzik L, Lowenstein CJ, Kunkel SL, Michel T, Kelly RA, Smith TW. Contractile responsiveness of ventricular myocytes to isoproterenol is regulated by induction of nitric oxide synthase activity in cardiac microvascular endothelial cells in heterotypic primary culture. Circulation Research. 77: 486-93. PMID 7543825 DOI: 10.1161/01.Res.77.3.486  0.597
1995 Balligand JL, Kobzik L, Han X, Kaye DM, Belhassen L, O'Hara DS, Kelly RA, Smith TW, Michel T. Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes. The Journal of Biological Chemistry. 270: 14582-6. PMID 7540173 DOI: 10.1074/Jbc.270.24.14582  0.653
1995 Balligand JL, Ungureanu-Longrois D, Simmons WW, Kobzik L, Lowenstein CJ, Lamas S, Kelly RA, Smith TW, Michel T. Induction of NO synthase in rat cardiac microvascular endothelial cells by IL-1 beta and IFN-gamma. The American Journal of Physiology. 268: H1293-303. PMID 7535006 DOI: 10.1152/Ajpheart.1995.268.3.H1293  0.701
1995 Robinson LJ, Busconi L, Michel T. Agonist-modulated Palmitoylation of Endothelial Nitric Oxide Synthase Journal of Biological Chemistry. 270: 995-998. PMID 7530714 DOI: 10.1074/Jbc.270.3.995  0.438
1995 Lee CM, Robinson LJ, Michel T. Oligomerization of endothelial nitric oxide synthase. Evidence for a dominant negative effect of truncation mutants. Journal of Biological Chemistry. 270: 27403-27406. PMID 7499193 DOI: 10.1074/Jbc.270.46.27403  0.398
1995 Sase K, Michel T. Expression of constitutive endothelial nitric oxide synthase in human blood platelets Life Sciences. 57: 2049-2055. PMID 7475956 DOI: 10.1016/0024-3205(95)02191-K  0.324
1994 Shaul PW, North AJ, Wu LC, Wells LB, Brannon TS, Lau KS, Michel T, Margraf LR, Star RA. Endothelial nitric oxide synthase is expressed in cultured human bronchiolar epithelium. The Journal of Clinical Investigation. 94: 2231-6. PMID 7527428 DOI: 10.1172/Jci117585  0.414
1994 Buttery LDK, McCarthy A, Springall DR, Sullivan MHF, Elder MG, Michel T, Polak JM. Endothelial nitric oxide synthase in the human placenta: Regional distribution and proposed regulatory role at the feto-maternal interface Placenta. 15: 257-265. PMID 7520584 DOI: 10.1016/0143-4004(94)90017-5  0.381
1994 Robinson LJ, Weremowicz S, Morton CC, Michel T. Isolation and chromosomal localization of the human endothelial nitric oxide synthase (NOS3) gene Genomics. 19: 350-357. PMID 7514568 DOI: 10.1006/Geno.1994.1068  0.329
1993 Balligand J, Ungureanu D, Kelly RA, Kobzik L, Pimental D, Michel T, Smith TW. Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. Journal of Clinical Investigation. 91: 2314-2319. PMID 8486792 DOI: 10.1172/Jci116461  0.596
1993 Michel T, Smith TW. Nitric oxide synthases and cardiovascular signaling The American Journal of Cardiology. 72. PMID 7690516 DOI: 10.1016/0002-9149(93)90253-9  0.457
1993 Michel T, Li GK, Busconi L. Phosphorylation and subcellular translocation of endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 90: 6252-6256. PMID 7687064 DOI: 10.1073/Pnas.90.13.6252  0.431
1993 Balligand JL, Kelly RA, Marsden PA, Smith TW, Michel T. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system Proceedings of the National Academy of Sciences of the United States of America. 90: 347-351. PMID 7678347 DOI: 10.1073/Pnas.90.1.347  0.612
1992 Lamas S, Michel T, Collins T, Brenner BM, Marsden PA. Effects of interferon-γ on nitric oxide synthase activity and endothelin- 1 production by vascular endothelial cells Journal of Clinical Investigation. 90: 879-887. PMID 1381725 DOI: 10.1172/Jci115963  0.577
1992 Marsden PA, Schappert KT, Chen HS, Flowers M, Sundell CL, Wilcox JN, Lamas S, Michel T. Molecular cloning and characterization of human endothelial nitric oxide synthase Febs Letters. 307: 287-293. PMID 1379542 DOI: 10.1016/0014-5793(92)80697-F  0.626
1992 Lamas S, Marsden PA, Li GK, Tempst P, Michel T. Endothelial nitric oxide synthase: Molecular cloning and characterization of a distinct constitutive enzyme isoform Proceedings of the National Academy of Sciences of the United States of America. 89: 6348-6352. PMID 1378626 DOI: 10.1073/Pnas.89.14.6348  0.606
1992 Stamler JS, Simon DI, Osborne JA, Mullins ME, Jaraki O, Michel T, Singel DJ, Loscalzo J. S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds. Proceedings of the National Academy of Sciences of the United States of America. 89: 444-8. PMID 1346070 DOI: 10.1073/Pnas.89.1.444  0.352
1992 Michel T, Lamas S. Molecular cloning of constitutive endothelial nitric oxide synthase: evidence for a family of related genes. Journal of Cardiovascular Pharmacology. 20. PMID 1282983 DOI: 10.1097/00005344-199204002-00014  0.609
1992 Balligand J, Kelly RA, Smith TW, Michel T. Regulation of cardiac myocyte function by a constitutive no signalling pathway Journal of Molecular and Cellular Cardiology. 24: 177. DOI: 10.1016/0022-2828(92)90555-E  0.574
1991 Lamas S, Michel T, Brenner BM, Marsden PA. Nitric oxidec synthesis in endothelial cells: Evidence for a pathway inducible by TNF-α American Journal of Physiology - Cell Physiology. 261. PMID 1656767 DOI: 10.1152/Ajpcell.1991.261.4.C634  0.578
1984 García-Sáinz JA, Boyer JL, Michel T, Sawyer D, Stiles GL, Dohlman H, Lefkowitz RJ. Effect of pertussis toxin on alpha 2-adrenoceptors: decreased formation of the high-affinity state for agonists. Febs Letters. 172: 95-8. PMID 6329826 DOI: 10.1016/0014-5793(84)80881-9  0.505
1984 Nambi P, Sibley DR, Stadel JM, Michel T, Peters JR, Lefkowitz RJ. Cell-free desensitization of catecholamine-sensitive adenylate cyclase. Agonist- and cAMP-promoted alterations in turkey erythrocyte beta-adrenergic receptors. Journal of Biological Chemistry. 259: 4629-4633. DOI: 10.1016/s0021-9258(17)43093-6  0.526
1983 Lefkowitz RJ, Michel T. Plasma membrane receptors. The Journal of Clinical Investigation. 72: 1185-9. PMID 6313753 DOI: 10.1172/Jci111073  0.405
1982 Hoffman BB, Michel T, Brenneman TB, Lefkowitz RJ. Interactions of agonists with platelet alpha 2-adrenergic receptors. Endocrinology. 110: 926-32. PMID 6120077 DOI: 10.1210/Endo-110-3-926  0.44
1982 Michel T, Hoffman BB, Lefkowitz RJ. CHAPTER 2 – Regulation of Adenylate Cyclase by Adrenergic Receptors Biochemical Actions of Hormones. 43-68. DOI: 10.1016/B978-0-12-452809-3.50007-5  0.44
1981 Michel T, Hoffman BB, Lefkowitz RJ, Caron MG. Different sedimentation properties of agonist- and antagonist-labelled platelet alpha 2 adrenergic receptors. Biochemical and Biophysical Research Communications. 100: 1131-6. PMID 6268079 DOI: 10.1016/0006-291X(81)91941-0  0.498
1981 Michel T, Hoffman BB, Lefkowitz RJ. Differential regulation of the alpha 2-adrenergic receptor by Na+ and guanine nucleotides. Nature. 288: 709-11. PMID 6256638 DOI: 10.1038/288709A0  0.445
1980 Hoffman BB, Michel T, Kilpatrick DM, Lefkowitz RJ, Tolbert ME, Gilman H, Fain JN. Agonist versus antagonist binding to alpha-adrenergic receptors. Proceedings of the National Academy of Sciences of the United States of America. 77: 4569-73. PMID 6107908 DOI: 10.1073/Pnas.77.8.4569  0.424
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