Melanie Ott - Publications

Affiliations: 
Gladstone Institute of Virology J. David Gladstone Institutes 
Website:
https://gladstone.org/people/melanie-ott

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rathore U, Haas P, Easwar Kumar V, Hiatt J, Haas KM, Bouhaddou M, Swaney DL, Stevenson E, Zuliani-Alvarez L, McGregor MJ, Turner-Groth A, Ochieng' Olwal C, Bediako Y, Braberg H, Soucheray M, ... Ott M, et al. CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. Mbio. e0222223. PMID 38411080 DOI: 10.1128/mbio.02222-23  0.343
2023 Li Z, Deeks SG, Ott M, Greene WC. Comprehensive synergy mapping links a BAF- and NSL-containing "supercomplex" to the transcriptional silencing of HIV-1. Cell Reports. 42: 113055. PMID 37682714 DOI: 10.1016/j.celrep.2023.113055  0.334
2023 Boehm D, Lam V, Schnolzer M, Ott M. The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11. Cell Reports. 42: 112234. PMID 36897778 DOI: 10.1016/j.celrep.2023.112234  0.353
2020 Bouhaddou M, Memon D, Meyer B, White KM, Rezelj VV, Correa Marrero M, Polacco BJ, Melnyk JE, Ulferts S, Kaake RM, Batra J, Richards AL, Stevenson E, Gordon DE, Rojc A, ... ... Ott M, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. PMID 32645325 DOI: 10.1016/J.Cell.2020.06.034  0.311
2020 Chen IP, Ott M. Turning up the heat on HIV-1. Proceedings of the National Academy of Sciences of the United States of America. 117: 16109-16111. PMID 32606243 DOI: 10.1073/Pnas.2010212117  0.436
2020 Leon K, Ott M. An 'Arms Race' between the Nonsense-mediated mRNA Decay Pathway and Viral Infections. Seminars in Cell & Developmental Biology. PMID 32553580 DOI: 10.1016/J.Semcdb.2020.05.018  0.318
2020 Vallejo-Gracia A, Chen IP, Perrone R, Besnard E, Boehm D, Battivelli E, Tezil T, Krey K, Raymond KA, Hull PA, Walter M, Habrylo I, Cruz A, Deeks S, Pillai S, ... ... Ott M, et al. FOXO1 promotes HIV latency by suppressing ER stress in T cells. Nature Microbiology. PMID 32541947 DOI: 10.1038/S41564-020-0742-9  0.453
2020 Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Huettenhain R, Kaake RM, Richards AL, Tutuncuoglu B, ... ... Ott M, et al. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. PMID 32353859 DOI: 10.1038/S41586-020-2286-9  0.322
2019 Schilling B, Meyer JG, Wei L, Ott M, Verdin E. High-Resolution Mass Spectrometry to Identify and Quantify Acetylation Protein Targets. Methods in Molecular Biology (Clifton, N.J.). 1983: 3-16. PMID 31087289 DOI: 10.1007/978-1-4939-9434-2_1  0.31
2019 Ali I, Ruiz DG, Ni Z, Johnson JR, Zhang H, Li PC, Khalid MM, Conrad RJ, Guo X, Min J, Greenblatt J, Jacobson M, Krogan NJ, Ott M. Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins. Molecular Cell. PMID 31054975 DOI: 10.1016/J.Molcel.2019.04.008  0.367
2018 Tomar S, Ali I, Ott M. A BAF'ling Approach to Curing HIV. Cell Chemical Biology. 25: 1441-1442. PMID 30576660 DOI: 10.1016/J.Chembiol.2018.12.007  0.373
2018 Fontaine KA, Leon KE, Khalid MM, Tomar S, Jimenez-Morales D, Dunlap M, Kaye JA, Shah PS, Finkbeiner S, Krogan NJ, Ott M. The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein. Mbio. 9. PMID 30401782 DOI: 10.1128/Mbio.02126-18  0.373
2018 Ali I, Conrad RJ, Verdin E, Ott M. Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics. Chemical Reviews. PMID 29405707 DOI: 10.1021/Acs.Chemrev.7B00181  0.364
2017 Jeng MY, Hull PA, Fei M, Kwon HS, Tsou CL, Kasler H, Ng CP, Gordon DE, Johnson J, Krogan N, Verdin E, Ott M. Metabolic reprogramming of human CD8+ memory T cells through loss of SIRT1. The Journal of Experimental Medicine. PMID 29191913 DOI: 10.1084/Jem.20161066  0.574
2017 Boehm D, Ott M. Host Methyltransferases and Demethylases: Potential New Epigenetic Targets for HIV Cure Strategies and Beyond. Aids Research and Human Retroviruses. 33: S8-S22. PMID 29140109 DOI: 10.1089/Aid.2017.0180  0.415
2017 Boehm D, Ott M. Flow Cytometric Analysis of HIV-1 Transcriptional Activity in Response to shRNA Knockdown in A2 and A72 J-Lat Cell Lines. Bio-Protocol. 7. PMID 29082287 DOI: 10.21769/BioProtoc.2314  0.366
2017 Conrad RJ, Fozouni P, Thomas S, Sy H, Zhang Q, Zhou MM, Ott M. The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin-Remodeling Complexes. Molecular Cell. PMID 28844864 DOI: 10.1016/J.Molcel.2017.07.025  0.45
2017 Boehm D, Ott M. Flow Cytometric Analysis of Drug-induced HIV-1 Transcriptional Activity in A2 and A72 J-Lat Cell Lines. Bio-Protocol. 7. PMID 28835903 DOI: 10.21769/BioProtoc.2290  0.313
2017 Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. Cell Host & Microbe. 21: 569-579.e6. PMID 28494238 DOI: 10.1016/J.Chom.2017.04.011  0.451
2016 Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, et al. The mTOR Complex Controls HIV Latency. Cell Host & Microbe. 20: 785-797. PMID 27978436 DOI: 10.1016/J.Chom.2016.11.001  0.405
2016 Khan S, Woodruff EM, Trapecar M, Fontaine KA, Ezaki A, Borbet TC, Ott M, Sanjabi S. Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication. The Journal of Experimental Medicine. PMID 27852793 DOI: 10.1084/Jem.20161289  0.349
2016 Ott M, Marques D, Funk C, Bailer SM. Asna1/TRC40 that mediates membrane insertion of tail-anchored proteins is required for efficient release of Herpes simplex virus 1 virions. Virology Journal. 13: 175. PMID 27765046 DOI: 10.1186/S12985-016-0638-8  0.33
2016 Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D, Margolis D, Mellors J, Persaud D, Tucker JD, ... ... Ott M, et al. International AIDS Society global scientific strategy: towards an HIV cure 2016. Nature Medicine. PMID 27400264 DOI: 10.1038/Nm.4108  0.341
2016 Shirakawa K, Wang L, Man N, Maksimoska J, Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E. Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity. Elife. 5. PMID 27244239 DOI: 10.7554/Elife.11156  0.358
2016 Ali I, Ramage H, Boehm D, Dirk LM, Sakane N, Hanada K, Pagans S, Kaehlcke K, Aul K, Weinberger L, Trievel R, Schnoelzer M, Kamada M, Houtz R, Ott M. The HIV-1 Tat protein is monomethylated at lysine-71 by the lysine methyltransferase KMT7. The Journal of Biological Chemistry. PMID 27235396 DOI: 10.1074/Jbc.M116.735415  0.435
2016 Conrad RJ, Ott M. Therapeutics Targeting Protein Acetylation Perturb Latency of Human Viruses. Acs Chemical Biology. PMID 26845514 DOI: 10.1021/Acschembio.5B00999  0.382
2015 Jeng MY, Ali I, Ott M. Manipulation of the host protein acetylation network by human immunodeficiency virus type 1. Critical Reviews in Biochemistry and Molecular Biology. 50: 314-25. PMID 26329395 DOI: 10.3109/10409238.2015.1061973  0.455
2015 Striebinger H, Zhang J, Ott M, Funk C, Radtke K, Duron J, Ruzsics Z, Haas J, Lippé R, Bailer SM. Subcellular trafficking and functional importance of Herpes simplex virus type 1 Glycoprotein M domains. The Journal of General Virology. PMID 26265177 DOI: 10.1099/Jgv.0.000262  0.306
2015 Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, ... ... Ott M, et al. SIRT1 deacetylates RORγt and enhances Th17 cell generation. The Journal of Experimental Medicine. 212: 973. PMID 25987725 DOI: 10.1084/jem.2013237805062015c  0.53
2015 Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, ... ... Ott M, et al. SIRT1 deacetylates RORγt and enhances Th17 cell generation. The Journal of Experimental Medicine. 212: 607-17. PMID 25918343 DOI: 10.1084/Jem.20132378  0.622
2015 Simonti CN, Pollard KS, Schröder S, He D, Bruneau BG, Ott M, Capra JA. Evolution of lysine acetylation in the RNA polymerase II C-terminal domain. Bmc Evolutionary Biology. 15: 35. PMID 25887984 DOI: 10.1186/S12862-015-0327-Z  0.334
2015 Ramage HR, Kumar GR, Verschueren E, Johnson JR, Von Dollen J, Johnson T, Newton B, Shah P, Horner J, Krogan NJ, Ott M. A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay. Molecular Cell. 57: 329-40. PMID 25616068 DOI: 10.1016/J.Molcel.2014.12.028  0.333
2015 Verdin E, Ott M. 50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond. Nature Reviews. Molecular Cell Biology. 16: 258-64. PMID 25549891 DOI: 10.1038/Nrm3931  0.372
2014 Camus G, Schweiger M, Herker E, Harris C, Kondratowicz AS, Tsou CL, Farese RV, Herath K, Previs SF, Roddy TP, Pinto S, Zechner R, Ott M. The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets. The Journal of Biological Chemistry. 289: 35770-80. PMID 25381252 DOI: 10.1074/Jbc.M114.587816  0.321
2013 Schröder S, Herker E, Itzen F, He D, Thomas S, Gilchrist DA, Kaehlcke K, Cho S, Pollard KS, Capra JA, Schnölzer M, Cole PA, Geyer M, Bruneau BG, Adelman K, ... Ott M, et al. Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells. Molecular Cell. 52: 314-24. PMID 24207025 DOI: 10.1016/J.Molcel.2013.10.009  0.365
2013 Camus G, Vogt DA, Kondratowicz AS, Ott M. Lipid droplets and viral infections. Methods in Cell Biology. 116: 167-90. PMID 24099293 DOI: 10.1016/B978-0-12-408051-5.00009-7  0.321
2013 Webster B, Ott M, Greene WC. Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus. Journal of Virology. 87: 13354-69. PMID 24089557 DOI: 10.1128/Jvi.02465-13  0.342
2013 Boehm D, Conrad RJ, Ott M. Bromodomain proteins in HIV infection. Viruses. 5: 1571-86. PMID 23793227 DOI: 10.3390/V5061571  0.447
2013 Ott M, Verdin E. Three rules for HIV latency: location, location, and location. Cell Host & Microbe. 13: 625-6. PMID 23768485 DOI: 10.1016/J.Chom.2013.05.016  0.39
2013 Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. Plos Pathogens. 9: e1003302. PMID 23593007 DOI: 10.1371/Journal.Ppat.1003302  0.336
2013 Camus G, Herker E, Modi AA, Haas JT, Ramage HR, Farese RV, Ott M. Diacylglycerol acyltransferase-1 localizes hepatitis C virus NS5A protein to lipid droplets and enhances NS5A interaction with the viral capsid core. The Journal of Biological Chemistry. 288: 9915-23. PMID 23420847 DOI: 10.1074/Jbc.M112.434910  0.34
2013 Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, Siliciano RF, Weinberger L, Verdin E, Ott M. BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism. Cell Cycle (Georgetown, Tex.). 12: 452-62. PMID 23255218 DOI: 10.4161/Cc.23309  0.462
2013 Knipe DM, Lieberman PM, Jung JU, McBride AA, Morris KV, Ott M, Margolis D, Nieto A, Nevels M, Parks RJ, Kristie TM. Snapshots: chromatin control of viral infection. Virology. 435: 141-56. PMID 23217624 DOI: 10.1016/J.Virol.2012.09.023  0.354
2013 Webster B, Wissing S, Herker E, Ott M, Greene WC. Rapid intracellular competition between hepatitis C viral genomes as a result of mitosis. Journal of Virology. 87: 581-96. PMID 23097449 DOI: 10.1128/Jvi.01047-12  0.329
2012 Kwon HS, Lim HW, Wu J, Schnölzer M, Verdin E, Ott M. Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 2712-21. PMID 22312127 DOI: 10.4049/Jimmunol.1100903  0.63
2012 Schröder S, Cho S, Zeng L, Zhang Q, Kaehlcke K, Mak L, Lau J, Bisgrove D, Schnölzer M, Verdin E, Zhou MM, Ott M. Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes. The Journal of Biological Chemistry. 287: 1090-9. PMID 22084242 DOI: 10.1074/Jbc.M111.282855  0.395
2011 Ott M, Geyer M, Zhou Q. The control of HIV transcription: keeping RNA polymerase II on track. Cell Host & Microbe. 10: 426-35. PMID 22100159 DOI: 10.1016/J.Chom.2011.11.002  0.43
2011 Harris C, Herker E, Farese RV, Ott M. Hepatitis C virus core protein decreases lipid droplet turnover: a mechanism for core-induced steatosis. The Journal of Biological Chemistry. 286: 42615-25. PMID 21984835 DOI: 10.1074/Jbc.M111.285148  0.316
2011 Sakane N, Kwon HS, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M. Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). Plos Pathogens. 7: e1002184. PMID 21876670 DOI: 10.1371/Journal.Ppat.1002184  0.679
2011 Ott M, Tascher G, Haßdenteufel S, Zimmermann R, Haas J, Bailer SM. Functional characterization of the essential tail anchor of the herpes simplex virus type 1 nuclear egress protein pUL34. The Journal of General Virology. 92: 2734-2745. PMID 21832006 DOI: 10.1099/Vir.0.032730-0  0.352
2011 Ott M. HIV never ceases to surprise: Innovative methods in the quest for a cure. Methods (San Diego, Calif.). 53: 1-2. PMID 21251605 DOI: 10.1016/J.Ymeth.2010.12.038  0.334
2011 Pagans S, Sakane N, Schnölzer M, Ott M. Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies. Methods (San Diego, Calif.). 53: 91-6. PMID 20615470 DOI: 10.1016/J.Ymeth.2010.07.001  0.368
2010 Herker E, Harris C, Hernandez C, Carpentier A, Kaehlcke K, Rosenberg AR, Farese RV, Ott M. Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. Nature Medicine. 16: 1295-8. PMID 20935628 DOI: 10.1038/Nm.2238  0.319
2010 Cho S, Schroeder S, Ott M. CYCLINg through transcription: posttranslational modifications of P-TEFb regulate transcription elongation. Cell Cycle (Georgetown, Tex.). 9: 1697-705. PMID 20436276 DOI: 10.4161/Cc.9.9.11346  0.376
2010 Pagans S, Kauder SE, Kaehlcke K, Sakane N, Schroeder S, Dormeyer W, Trievel RC, Verdin E, Schnolzer M, Ott M. The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription. Cell Host & Microbe. 7: 234-44. PMID 20227666 DOI: 10.1016/J.Chom.2010.02.005  0.434
2009 Cho S, Schroeder S, Kaehlcke K, Kwon HS, Pedal A, Herker E, Schnoelzer M, Ott M. Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells. The Embo Journal. 28: 1407-17. PMID 19387490 DOI: 10.1038/Emboj.2009.99  0.642
2008 Kwon HS, Ott M. The ups and downs of SIRT1. Trends in Biochemical Sciences. 33: 517-25. PMID 18805010 DOI: 10.1016/J.Tibs.2008.08.001  0.6
2008 Kwon HS, Brent MM, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M. Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Cell Host & Microbe. 3: 158-67. PMID 18329615 DOI: 10.1016/J.Chom.2008.02.002  0.676
2007 Hetzer C, Bisgrove D, Cohen MS, Pedal A, Kaehlcke K, Speyerer A, Bartscherer K, Taunton J, Ott M. Recruitment and activation of RSK2 by HIV-1 Tat. Plos One. 2: e151. PMID 17225856 DOI: 10.1371/Journal.Pone.0000151  0.443
2006 Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E. The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter. The Journal of Biological Chemistry. 281: 19960-8. PMID 16687403 DOI: 10.1074/Jbc.M603336200  0.448
2005 Dormeyer W, Ott M, Schnölzer M. Analysis of p300 acetyltransferase substrate specificity by MALDI TOF mass spectrometry. Methods (San Diego, Calif.). 36: 376-82. PMID 16085422 DOI: 10.1016/J.Ymeth.2005.03.006  0.327
2005 Hetzer C, Dormeyer W, Schnölzer M, Ott M. Decoding Tat: the biology of HIV Tat posttranslational modifications. Microbes and Infection. 7: 1364-9. PMID 16046164 DOI: 10.1016/J.Micinf.2005.06.003  0.446
2005 Dormeyer W, Ott M, Schnölzer M. Probing lysine acetylation in proteins: strategies, limitations, and pitfalls of in vitro acetyltransferase assays. Molecular & Cellular Proteomics : McP. 4: 1226-39. PMID 15933374 DOI: 10.1074/Mcp.M500047-Mcp200  0.371
2005 Pagans S, Pedal A, North BJ, Kaehlcke K, Marshall BL, Dorr A, Hetzer-Egger C, Henklein P, Frye R, McBurney MW, Hruby H, Jung M, Verdin E, Ott M. SIRT1 regulates HIV transcription via Tat deacetylation. Plos Biology. 3: e41. PMID 15719057 DOI: 10.1371/Journal.Pbio.0030041  0.462
2004 Schwer B, Ren S, Pietschmann T, Kartenbeck J, Kaehlcke K, Bartenschlager R, Yen TSB, Ott M. Targeting of hepatitis C virus core protein to mitochondria through a novel C-terminal localization motif Journal of Virology. 78: 7958-7968. PMID 15254168 DOI: 10.1128/Jvi.78.15.7958-7968.2004  0.316
2004 Ott M, Dorr A, Hetzer-Egger C, Kaehlcke K, Schnolzer M, Henklein P, Cole P, Zhou MM, Verdin E. Tat acetylation: a regulatory switch between early and late phases in HIV transcription elongation. Novartis Foundation Symposium. 259: 182-93; discussion 1. PMID 15171254 DOI: 10.1002/0470862637.Ch13  0.416
2004 Witte V, Laffert B, Rosorius O, Lischka P, Blume K, Galler G, Stilper A, Willbold D, D'Aloja P, Sixt M, Kolanus J, Ott M, Kolanus W, Schuler G, Baur AS. HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane. Molecular Cell. 13: 179-90. PMID 14759364 DOI: 10.1016/S1097-2765(04)00004-8  0.418
2003 Dormeyer W, Dorr A, Ott M, Schnölzer M. Acetylation of the HIV-1 Tat protein: An in vitro study Analytical and Bioanalytical Chemistry. 376: 994-1005. PMID 12904943 DOI: 10.1007/S00216-003-2058-Z  0.419
2003 Kaehlcke K, Dorr A, Hetzer-Egger C, Kiermer V, Henklein P, Schnoelzer M, Loret E, Cole PA, Verdin E, Ott M. Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation. Molecular Cell. 12: 167-76. PMID 12887902 DOI: 10.1016/S1097-2765(03)00245-4  0.395
2002 Schwer B, North BJ, Frye RA, Ott M, Verdin E. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. The Journal of Cell Biology. 158: 647-57. PMID 12186850 DOI: 10.1083/Jcb.200205057  0.308
2002 Dorr A, Kiermer V, Pedal A, Rackwitz HR, Henklein P, Schubert U, Zhou MM, Verdin E, Ott M. Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain. The Embo Journal. 21: 2715-23. PMID 12032084 DOI: 10.1093/Emboj/21.11.2715  0.459
2002 Mujtaba S, He Y, Zeng L, Farooq A, Carlson JE, Ott M, Verdin E, Zhou MM. Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain. Molecular Cell. 9: 575-86. PMID 11931765 DOI: 10.1016/S1097-2765(02)00483-5  0.453
2001 Köller H, Schaal H, Freund M, Garrido SR, von Giesen HJ, Ott M, Rosenbaum C, Arendt G. HIV-1 protein Tat reduces the glutamate-induced intracellular Ca2+ increase in cultured cortical astrocytes. The European Journal of Neuroscience. 14: 1793-9. PMID 11860474 DOI: 10.1046/J.0953-816X.2001.01808.X  0.36
1999 Ott M, Schnölzer M, Garnica J, Fischle W, Emiliani S, Rackwitz HR, Verdin E. Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity. Current Biology : Cb. 9: 1489-92. PMID 10607594 DOI: 10.1016/S0960-9822(00)80120-7  0.472
1998 Emiliani S, Fischle W, Ott M, Van Lint C, Amella CA, Verdin E. Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line. Journal of Virology. 72: 1666-70. PMID 9445075 DOI: 10.1128/Jvi.72.2.1666-1670.1998  0.398
1997 Ott M, Emiliani S, Van Lint C, Herbein G, Lovett J, Chirmule N, McCloskey T, Pahwa S, Verdin E. Immune hyperactivation of HIV-1-infected T cells mediated by Tat and the CD28 pathway. Science (New York, N.Y.). 275: 1481-5. PMID 9045614 DOI: 10.1126/Science.275.5305.1481  0.375
1996 Emiliani S, Van Lint C, Fischle W, Paras P, Ott M, Brady J, Verdin E. A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency. Proceedings of the National Academy of Sciences of the United States of America. 93: 6377-81. PMID 8692823 DOI: 10.1073/Pnas.93.13.6377  0.371
1996 Van Lint C, Emiliani S, Ott M, Verdin E. Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. The Embo Journal. 15: 1112-20. PMID 8605881  0.334
1996 Van Lint C, Emiliani S, Ott M, Verdin E. Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. The Embo Journal. 15: 1112-1120. DOI: 10.1002/J.1460-2075.1996.Tb00449.X  0.438
1995 Verdin E, Van Lint C, Ott M, Emiliani S. Role of chromatin in the transcriptional regulation of HIV-1 Journal of Cancer Research and Clinical Oncology. 121: S36-S36. DOI: 10.1007/Bf02559898  0.414
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