Year |
Citation |
Score |
2016 |
Grandner JM, Cacho RA, Tang Y, Houk KN. Mechanism of the P450-Catalyzed Oxidative Cyclization in the Biosynthesis of Griseofulvin. Acs Catalysis. 6: 4506-4511. PMID 28503354 DOI: 10.1021/acscatal.6b01068 |
0.383 |
|
2016 |
Zhang J, Liu N, Cacho RA, Gong Z, Liu Z, Qin W, Tang C, Tang Y, Zhou J. Structural basis of nonribosomal peptide macrocyclization in fungi. Nature Chemical Biology. PMID 27748753 DOI: 10.1038/Nchembio.2202 |
0.334 |
|
2016 |
Cacho RA, Tang Y. Reconstitution of Fungal Nonribosomal Peptide Synthetases in Yeast and In Vitro. Methods in Molecular Biology (Clifton, N.J.). 1401: 103-19. PMID 26831704 DOI: 10.1007/978-1-4939-3375-4_7 |
0.395 |
|
2015 |
Cacho RA, Thuss J, Xu W, Sanichar R, Gao Z, Nguyen A, Vederas JC, Tang Y. Understanding Programming of Fungal Iterative Polyketide Synthases: the Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase. Journal of the American Chemical Society. PMID 26630357 DOI: 10.1021/Jacs.5B11814 |
0.337 |
|
2015 |
Tang MC, Lin HC, Li D, Zou Y, Li J, Xu W, Cacho RA, Hillenmeyer ME, Garg NK, Tang Y. Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast. Journal of the American Chemical Society. PMID 26469304 DOI: 10.1021/Jacs.5B06108 |
0.465 |
|
2015 |
Zou Y, Zhan Z, Li D, Tang M, Cacho RA, Watanabe K, Tang Y. Tandem prenyltransferases catalyze isoprenoid elongation and complexity generation in biosynthesis of quinolone alkaloids. Journal of the American Chemical Society. 137: 4980-3. PMID 25859931 DOI: 10.1021/Jacs.5B03022 |
0.444 |
|
2014 |
Cacho RA, Tang Y, Chooi YH. Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi. Frontiers in Microbiology. 5: 774. PMID 25642215 DOI: 10.3389/Fmicb.2014.00774 |
0.631 |
|
2013 |
Chooi YH, Hong YJ, Cacho RA, Tantillo DJ, Tang Y. A cytochrome P450 serves as an unexpected terpene cyclase during fungal meroterpenoid biosynthesis. Journal of the American Chemical Society. 135: 16805-8. PMID 24161266 DOI: 10.1021/Ja408966T |
0.654 |
|
2013 |
Cacho RA, Chooi YH, Zhou H, Tang Y. Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin. Acs Chemical Biology. 8: 2322-30. PMID 23978092 DOI: 10.1021/Cb400541Z |
0.68 |
|
2013 |
Yin WB, Chooi YH, Smith AR, Cacho RA, Hu Y, White TC, Tang Y. Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in Aspergillus nidulans. Acs Synthetic Biology. 2: 629-34. PMID 23758576 DOI: 10.1021/Sb400048B |
0.633 |
|
2013 |
Jiang W, Cacho RA, Chiou G, Garg NK, Tang Y, Walsh CT. EcdGHK are three tailoring iron oxygenases for amino acid building blocks of the echinocandin scaffold. Journal of the American Chemical Society. 135: 4457-66. PMID 23451921 DOI: 10.1021/Ja312572V |
0.379 |
|
2013 |
Cacho RA, Tang Y. Bringing protein engineering and natural product biosynthesis together. Chemistry & Biology. 20: 3-5. PMID 23352133 DOI: 10.1016/j.chembiol.2013.01.005 |
0.451 |
|
2012 |
Cacho RA, Jiang W, Chooi YH, Walsh CT, Tang Y. Identification and characterization of the echinocandin B biosynthetic gene cluster from Emericella rugulosa NRRL 11440. Journal of the American Chemical Society. 134: 16781-90. PMID 22998630 DOI: 10.1021/Ja307220Z |
0.641 |
|
2012 |
Zabala AO, Cacho RA, Tang Y. Protein engineering towards natural product synthesis and diversification. Journal of Industrial Microbiology & Biotechnology. 39: 227-41. PMID 22006344 DOI: 10.1007/S10295-011-1044-2 |
0.563 |
|
2010 |
Chooi YH, Cacho R, Tang Y. Identification of the viridicatumtoxin and griseofulvin gene clusters from Penicillium aethiopicum. Chemistry & Biology. 17: 483-94. PMID 20534346 DOI: 10.1016/J.Chembiol.2010.03.015 |
0.643 |
|
2009 |
Gao X, Xie X, Pashkov I, Sawaya MR, Laidman J, Zhang W, Cacho R, Yeates TO, Tang Y. Directed evolution and structural characterization of a simvastatin synthase. Chemistry & Biology. 16: 1064-74. PMID 19875080 DOI: 10.1016/J.Chembiol.2009.09.017 |
0.623 |
|
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