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Steven O. Mansoorabadi, Ph.D.

Affiliations: 
2006 University of Wisconsin, Madison, Madison, WI 
 2012- Chemistry and Biochemistry Auburn University, Auburn, AL, United States 
Area:
Biochemistry, General Biophysics
Website:
https://www.auburn.edu/cosam/faculty/chemistry/mansoorabadi/index.htm
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Parents

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George H. Reed grad student 2006 UW Madison
 (Characterization of paramagnetic intermediates in enzymatic reactions.)
Hung-Wen (Ben) Liu post-doc 2006-2012 UT Austin

Children

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Phong Ngo grad student Auburn University

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Publications

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Donnan PH, Mansoorabadi SO. (2022) Broken-Symmetry Density Functional Theory Analysis of the Ω Intermediate in Radical -Adenosyl-l-methionine Enzymes: Evidence for a Near-Attack Conformer over an Organometallic Species. Journal of the American Chemical Society. 144: 3381-3385
Donnan PH, Ngo PD, Mansoorabadi SO. (2017) Constant pH Accelerated Molecular Dynamics Investigation of the pH Regulation Mechanism of Dinoflagellate Luciferase. Biochemistry
Pierce E, Mansoorabadi SO, Can M, et al. (2017) Properties of intermediates in the catalytic cycle of oxalate oxidoreductase and its suicide inactivation by pyruvate. Biochemistry
Zheng K, Ngo PD, Owens VL, et al. (2016) The biosynthetic pathway of coenzyme F430 in methanogenic and methanotrophic archaea. Science (New York, N.Y.). 354: 339-342
Ngo PD, Mansoorabadi SO, Frey PA. (2016) Serine Protease Catalysis: A Computational Study of Tetrahedral Intermediates and Inhibitory Adducts. The Journal of Physical Chemistry. B
Mansoorabadi SO, Wu M, Tao Z, et al. (2014) Conformational activation of poly(ADP-ribose) polymerase-1 upon DNA binding revealed by small-angle X-ray scattering. Biochemistry. 53: 1779-88
Kim HJ, McCarty RM, Ogasawara Y, et al. (2013) GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme. Journal of the American Chemical Society. 135: 8093-6
Chang WC, Mansoorabadi SO, Liu HW. (2013) Reaction of HppE with substrate analogues: evidence for carbon-phosphorus bond cleavage by a carbocation rearrangement. Journal of the American Chemical Society. 135: 8153-6
Chang WC, Dey M, Liu P, et al. (2013) Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction. Nature. 496: 114-8
Huang H, Chang WC, Pai PJ, et al. (2012) Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analogues. Journal of the American Chemical Society. 134: 16171-4
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