| Year |
Citation |
Score |
| 2019 |
Iyer S, Sam FS, DiPrimio N, Preston G, Verheijen J, Murthy K, Parton Z, Tsang H, Lao J, Morava E, Perlstein EO. Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG. Disease Models & Mechanisms. PMID 31636082 DOI: 10.1242/Dmm.040584 |
0.307 |
|
| 2019 |
Iyer S, Mast JD, Tsang H, Rodriguez TP, DiPrimio N, Prangley M, Sam FS, Parton Z, Perlstein EO. Drug screens of NGLY1 Deficiency worm and fly models reveal catecholamine, NRF2 and anti-inflammatory pathway activation as potential clinical approaches. Disease Models & Mechanisms. PMID 31615832 DOI: 10.1242/Dmm.040576 |
0.385 |
|
| 2018 |
Lao JP, DiPrimio N, Prangley M, Sam FS, Mast JD, Perlstein EO. Yeast Models Of Phosphomannomutase 2 Deficiency, A Congenital Disorder Of Glycosylation. G3 (Bethesda, Md.). PMID 30530630 DOI: 10.1534/G3.118.200934 |
0.353 |
|
| 2018 |
Granatosky EA, DiPrimio N, Pickering JRE, Stevens DC, Perlstein EO, Taylor RE. GEX1A, a Polyketide from Streptomyces chromofuscus, Corrects the Cellular Defects Associated with Niemann-Pick Type C1 in Human Fibroblasts. Journal of Natural Products. PMID 30188717 DOI: 10.1021/Acs.Jnatprod.8B00314 |
0.317 |
|
| 2018 |
Rodriguez TP, Mast JD, Hartl T, Lee T, Sand P, Perlstein EO. Defects in the Neuroendocrine Axis Contribute to Global Development Delay in a Model of NGLY1 Deficiency. G3 (Bethesda, Md.). PMID 29735526 DOI: 10.1534/G3.118.300578 |
0.359 |
|
| 2010 |
Rainey MM, Korostyshevsky D, Lee S, Perlstein EO. The antidepressant sertraline targets intracellular vesiculogenic membranes in yeast. Genetics. 185: 1221-33. PMID 20457874 DOI: 10.1534/Genetics.110.117846 |
0.332 |
|
| 2009 |
Chen BJ, Causton HC, Mancenido D, Goddard NL, Perlstein EO, Pe'er D. Harnessing gene expression to identify the genetic basis of drug resistance. Molecular Systems Biology. 5: 310. PMID 19888205 DOI: 10.1038/Msb.2009.69 |
0.335 |
|
| 2009 |
Ruderfer DM, Roberts DC, Schreiber SL, Perlstein EO, Kruglyak L. Using expression and genotype to predict drug response in yeast. Plos One. 4: e6907. PMID 19730698 DOI: 10.1371/Journal.Pone.0006907 |
0.467 |
|
| 2009 |
de Bivort BL, Perlstein EO, Kunes S, Schreiber SL. Amino acid metabolic origin as an evolutionary influence on protein sequence in yeast. Journal of Molecular Evolution. 68: 490-7. PMID 19357800 DOI: 10.1007/S00239-009-9218-5 |
0.418 |
|
| 2007 |
Floto RA, Sarkar S, Perlstein EO, Kampmann B, Schreiber SL, Rubinsztein DC. Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages. Autophagy. 3: 620-2. PMID 17786022 DOI: 10.4161/Auto.4898 |
0.512 |
|
| 2007 |
Perlstein EO, de Bivort BL, Kunes S, Schreiber SL. Evolutionarily conserved optimization of amino acid biosynthesis. Journal of Molecular Evolution. 65: 186-96. PMID 17684697 DOI: 10.1007/S00239-007-0013-X |
0.413 |
|
| 2007 |
Perlstein EO, Deeds EJ, Ashenberg O, Shakhnovich EI, Schreiber SL. Quantifying fitness distributions and phenotypic relationships in recombinant yeast populations. Proceedings of the National Academy of Sciences of the United States of America. 104: 10553-8. PMID 17566105 DOI: 10.1073/Pnas.0704037104 |
0.429 |
|
| 2007 |
Sarkar S, Perlstein EO, Imarisio S, Pineau S, Cordenier A, Maglathlin RL, Webster JA, Lewis TA, O'Kane CJ, Schreiber SL, Rubinsztein DC. Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. Nature Chemical Biology. 3: 331-8. PMID 17486044 DOI: 10.1038/Nchembio883 |
0.518 |
|
| 2007 |
Perlstein EO, Ruderfer DM, Roberts DC, Schreiber SL, Kruglyak L. Genetic basis of individual differences in the response to small-molecule drugs in yeast. Nature Genetics. 39: 496-502. PMID 17334364 DOI: 10.1038/Ng1991 |
0.499 |
|
| 2006 |
Perlstein EO, Ruderfer DM, Ramachandran G, Haggarty SJ, Kruglyak L, Schreiber SL. Revealing complex traits with small molecules and naturally recombinant yeast strains. Chemistry & Biology. 13: 319-27. PMID 16638537 DOI: 10.1016/J.Chembiol.2006.01.010 |
0.617 |
|
| 2006 |
Butcher RA, Bhullar BS, Perlstein EO, Marsischky G, LaBaer J, Schreiber SL. Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway Nature Chemical Biology. 2: 103-109. PMID 16415861 DOI: 10.1038/Nchembio762 |
0.513 |
|
| 2006 |
Bradner JE, Shen JP, Perlstein EO, Divakaran S, Greenberg EF, Amaravadi R, Schreiber SL. Discovery and Characterization of Small Molecule Inhibitors of Autophagy for Cancer Therapy. Blood. 108: 2606-2606. DOI: 10.1182/Blood.V108.11.2606.2606 |
0.57 |
|
| 2004 |
Lo MM, Neumann CS, Nagayama S, Perlstein EO, Schreiber SL. A library of spirooxindoles based on a stereoselective three-component coupling reaction. Journal of the American Chemical Society. 126: 16077-86. PMID 15584743 DOI: 10.1021/Ja045089D |
0.618 |
|
| 2004 |
Bernstein BE, Liu CL, Humphrey EL, Perlstein EO, Schreiber SL. Global nucleosome occupancy in yeast. Genome Biology. 5: R62. PMID 15345046 DOI: 10.1186/Gb-2004-5-9-R62 |
0.533 |
|
| 1998 |
Weidanz JA, Card KF, Edwards A, Perlstein E, Wong HC. Display of functional αβ single-chain T-cell receptor molecules on the surface of bacteriophage Journal of Immunological Methods. 221: 59-76. PMID 9894898 DOI: 10.1016/S0022-1759(98)00153-7 |
0.301 |
|
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