Salvatore Oddo, Ph.D. - Publications

Affiliations: 
2005 University of California, Irvine, Irvine, CA 

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Rizzo MG, De Plano LM, Palermo N, Franco D, Nicolò M, Sciuto EL, Calabrese G, Oddo S, Conoci S, Guglielmino SPP. A Novel Serum-Based Diagnosis of Alzheimer's Disease Using an Advanced Phage-Based Biochip. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2301650. PMID 37150869 DOI: 10.1002/advs.202301650  0.401
2023 De Plano LM, Calabrese G, Rizzo MG, Oddo S, Caccamo A. The Role of the Transcription Factor Nrf2 in Alzheimer's Disease: Therapeutic Opportunities. Biomolecules. 13. PMID 36979483 DOI: 10.3390/biom13030549  0.405
2022 Engelender S, Stefanis L, Oddo S, Bellucci A. Can We Treat Neurodegenerative Proteinopathies by Enhancing Protein Degradation? Movement Disorders : Official Journal of the Movement Disorder Society. PMID 35579450 DOI: 10.1002/mds.29058  0.311
2019 Vartak RS, Rodin A, Oddo S. Differential activation of the mTOR/autophagy pathway predicts cognitive performance in APP/PS1 mice. Neurobiology of Aging. 83: 105-113. PMID 31585361 DOI: 10.1016/j.neurobiolaging.2019.08.018  0.357
2019 Velazquez R, Ferreira E, Knowles S, Fux C, Rodin A, Winslow W, Oddo S. Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation. Aging Cell. e13037. PMID 31560162 DOI: 10.1111/Acel.13037  0.45
2019 Velazquez R, Ferreira E, Winslow W, Dave N, Piras IS, Naymik M, Huentelman MJ, Tran A, Caccamo A, Oddo S. Maternal choline supplementation ameliorates Alzheimer's disease pathology by reducing brain homocysteine levels across multiple generations. Molecular Psychiatry. PMID 30622336 DOI: 10.1038/S41380-018-0322-Z  0.337
2018 Belfiore R, Rodin A, Ferreira E, Velazquez R, Branca C, Caccamo A, Oddo S. Temporal and regional progression of Alzheimer's disease-like pathology in 3xTg-AD mice. Aging Cell. e12873. PMID 30488653 DOI: 10.1111/Acel.12873  0.492
2018 Velazquez R, Ferreira E, Tran A, Turner EC, Belfiore R, Branca C, Oddo S. Acute tau knockdown in the hippocampus of adult mice causes learning and memory deficits. Aging Cell. e12775. PMID 29749079 DOI: 10.1111/Acel.12775  0.376
2018 Caccamo A, Belfiore R, Oddo S. Genetically reducing mTOR signaling rescues central insulin dysregulation in a mouse model of Alzheimer's disease. Neurobiology of Aging. 68: 59-67. PMID 29729422 DOI: 10.1016/j.neurobiolaging.2018.03.032  0.417
2018 Velazquez R, Tran A, Ishimwe E, Denner L, Dave N, Oddo S, Dineley KT. Corrigendum to "Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease" [Neurobiol. Aging 58 (2017) 1-13]. Neurobiology of Aging. 65: 235-238. PMID 29580440 DOI: 10.1016/J.Neurobiolaging.2018.02.010  0.364
2018 Caccamo A, Branca C, Oddo S. S3-02-01: Necroptosis Activation In Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2735  0.383
2017 Branca C, Ferreira E, Nguyen TV, Doyle K, Caccamo A, Oddo S. Genetic reduction of Nrf2 exacerbates cognitive deficits in a mouse model of Alzheimer's disease. Human Molecular Genetics. PMID 29036636 DOI: 10.1093/Hmg/Ddx361  0.436
2017 Velazquez R, Tran A, Ishimwe E, Denner L, Dave N, Oddo S, Dineley KT. Corrigendum to "Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease" [Neurobiol. Aging 58 (2017) 1-13]. Neurobiology of Aging. 58: 241. PMID 28863813 DOI: 10.1016/J.Neurobiolaging.2017.08.011  0.364
2017 Branca C, Shaw DM, Belfiore R, Gokhale V, Shaw AY, Foley C, Smith B, Hulme C, Dunckley T, Meechoovet B, Caccamo A, Oddo S. Dyrk1 inhibition improves Alzheimer's disease-like pathology. Aging Cell. PMID 28779511 DOI: 10.1111/Acel.12648  0.511
2017 Caccamo A, Branca C, Piras IS, Ferreira E, Huentelman MJ, Liang WS, Readhead B, Dudley JT, Spangenberg EE, Green KN, Belfiore R, Winslow W, Oddo S. Necroptosis activation in Alzheimer's disease. Nature Neuroscience. PMID 28758999 DOI: 10.1038/Nn.4608  0.607
2017 Velazquez R, Tran A, Ishimwe E, Denner L, Dave N, Oddo S, Dineley KT. Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease. Neurobiology of Aging. 58: 1-13. PMID 28688899 DOI: 10.1016/J.Neurobiolaging.2017.06.003  0.31
2017 Oddo S, Caccamo A, Branca C. [P2-177]: NECROPTOSIS AS A NOVEL MECHANISM UNDERLYING NEURONAL LOSS IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 13: P674-P674. DOI: 10.1016/J.Jalz.2017.06.828  0.4
2017 Caccamo A, Branca C, Ferreira E, Oddo S. [P2-156]: INCREASED SUSCEPTIBILITY TO NECROPTOSIS IN APP/PS1 MICE Alzheimer's & Dementia. 13: P667-P667. DOI: 10.1016/J.Jalz.2017.06.807  0.381
2016 Norambuena A, Wallrabe H, McMahon L, Silva A, Swanson E, Khan SS, Baerthlein D, Kodis E, Oddo S, Mandell JW, Bloom GS. mTOR and neuronal cell cycle reentry: How impaired brain insulin signaling promotes Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27693185 DOI: 10.1016/J.Jalz.2016.08.015  0.362
2016 Caccamo A, Ferreira E, Branca C, Oddo S. p62 improves AD-like pathology by increasing autophagy. Molecular Psychiatry. PMID 27573878 DOI: 10.1038/mp.2016.139  0.456
2016 Velazquez R, Shaw DM, Caccamo A, Oddo S. Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease. Molecular Neurodegeneration. 11: 52. PMID 27412291 DOI: 10.1186/S13024-016-0118-Z  0.472
2016 Ferreira E, Shaw DM, Oddo S. Identification of learning-induced changes in protein networks in the hippocampi of a mouse model of Alzheimer's disease. Translational Psychiatry. 6: e849. PMID 27378549 DOI: 10.1038/tp.2016.114  0.393
2016 Norambuena A, Wallrabe H, McMahon L, Silva A, Swanson E, Khan S, Baerthlein D, Kodis E, Oddo S, Mandell JW, Bloom GS. P3-120: Dysregulated MTOR Signaling is a Seminal Step in Alzheimer's Disease Pathogenesis Alzheimer's & Dementia. 12: P865-P865. DOI: 10.1016/J.Jalz.2016.06.1778  0.4
2015 Talboom JS, Velazquez R, Oddo S. The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer's disease. Npj Aging and Mechanisms of Disease. 1: 15008. PMID 28721257 DOI: 10.1038/npjamd.2015.8  0.325
2015 Mastroeni D, Delvaux E, Nolz J, Tan Y, Grover A, Oddo S, Coleman PD. Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease. Neurobiology of Aging. 36: 3121-9. PMID 26553823 DOI: 10.1016/J.Neurobiolaging.2015.08.017  0.467
2015 Caccamo A, Branca C, Talboom JS, Shaw DM, Turner D, Ma L, Messina A, Huang Z, Wu J, Oddo S. Reducing Ribosomal Protein S6 Kinase 1 Expression Improves Spatial Memory and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14042-56. PMID 26468204 DOI: 10.1523/Jneurosci.2781-15.2015  0.54
2015 Caccamo A, Shaw DM, Guarino F, Messina A, Walker AW, Oddo S. Reduced protein turnover mediates functional deficits in transgenic mice expressing the 25 kDa C-terminal fragment of TDP-43. Human Molecular Genetics. 24: 4625-35. PMID 26002100 DOI: 10.1093/Hmg/Ddv193  0.39
2015 Richardson A, Galvan V, Lin AL, Oddo S. How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story. Experimental Gerontology. 68: 51-8. PMID 25481271 DOI: 10.1016/J.Exger.2014.12.002  0.517
2015 Oddo S, Caccamo A, Talboom JS, Branca C. O2-12-02: Reducing ribosomal protein s6 kinase 1 ameliorates Alzheimer's disease-like cognitive and synaptic deficits by reducing bace-1 translation Alzheimer's & Dementia. 11: P203-P203. DOI: 10.1016/J.Jalz.2015.07.196  0.375
2015 Talboom JS, Orr M, Caccamo A, Oddo S. P3-043: Chemogenetic facilitation of neuronal depolarization ameliorates Alzheimer's disease-like cognitive deficits Alzheimer's & Dementia. 11: P634-P635. DOI: 10.1016/J.Jalz.2015.06.909  0.397
2015 Norambuena A, Wallrabe H, McMahon L, Swanson E, Thomas S, Baerthlein D, Silva A, Oddo S, Mandell JW, Bloom GS. P3-035: Mtor and rac1 control-induced, tau-dependent cell cycle re-entry in Alzheimer's disease neurons: A mechanistic explanation for classifying Alzheimer's disease as type 3 diabetes Alzheimer's & Dementia. 11: P632-P632. DOI: 10.1016/J.Jalz.2015.06.901  0.436
2014 Branca C, Wisely EV, Hartman LK, Caccamo A, Oddo S. Administration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease. Neurobiology of Aging. 35: 2726-35. PMID 25034342 DOI: 10.1016/J.Neurobiolaging.2014.06.011  0.562
2014 Caccamo A, De Pinto V, Messina A, Branca C, Oddo S. Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7988-98. PMID 24899720 DOI: 10.1523/Jneurosci.0777-14.2014  0.503
2014 Wisely EV, Xiang YK, Oddo S. Genetic suppression of β2-adrenergic receptors ameliorates tau pathology in a mouse model of tauopathies. Human Molecular Genetics. 23: 4024-34. PMID 24626633 DOI: 10.1093/Hmg/Ddu116  0.56
2014 Orr ME, Salinas A, Buffenstein R, Oddo S. Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology. Neurobiology of Aging. 35: 1233-42. PMID 24411482 DOI: 10.1016/J.Neurobiolaging.2013.12.006  0.444
2014 Edrey YH, Oddo S, Cornelius C, Caccamo A, Calabrese V, Buffenstein R. Oxidative damage and amyloid-β metabolism in brain regions of the longest-lived rodents. Journal of Neuroscience Research. 92: 195-205. PMID 24273049 DOI: 10.1002/Jnr.23320  0.333
2014 Medina DX, Orr ME, Oddo S. Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice. Neurobiology of Aging. 35: 79-87. PMID 23954172 DOI: 10.1016/J.Neurobiolaging.2013.07.006  0.416
2014 Caccamo A, Oddo S. O2-12-03: GENETIC REDUCTION OF MTOR SIGNALING AMELIORATES ALZHEIMER'S DISEASE-RELATED COGNITIVE DEFICITS AND AMYLOID-B PATHOLOGY BY RESTORING HIPPOCAMPAL GENE EXPRESSION SIGNATURE Alzheimer's & Dementia. 10: P192-P192. DOI: 10.1016/J.Jalz.2014.04.224  0.513
2013 Orr ME, Oddo S. Autophagic/lysosomal dysfunction in Alzheimer's disease. Alzheimer's Research & Therapy. 5: 53. PMID 24171818 DOI: 10.1186/Alzrt217  0.507
2013 Edrey YH, Medina DX, Gaczynska M, Osmulski PA, Oddo S, Caccamo A, Buffenstein R. Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease. Neurobiology of Aging. 34: 2352-60. PMID 23618870 DOI: 10.1016/J.Neurobiolaging.2013.03.032  0.552
2013 Wang D, Fu Q, Zhou Y, Xu B, Shi Q, Igwe B, Matt L, Hell JW, Wisely EV, Oddo S, Xiang YK. β2 adrenergic receptor, protein kinase A (PKA) and c-Jun N-terminal kinase (JNK) signaling pathways mediate tau pathology in Alzheimer disease models. The Journal of Biological Chemistry. 288: 10298-307. PMID 23430246 DOI: 10.1074/Jbc.M112.415141  0.516
2013 Caccamo A, Magrì A, Medina DX, Wisely EV, López-Aranda MF, Silva AJ, Oddo S. mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies. Aging Cell. 12: 370-80. PMID 23425014 DOI: 10.1111/Acel.12057  0.486
2013 Caccamo A, Medina DX, Oddo S. Glucocorticoids exacerbate cognitive deficits in TDP-25 transgenic mice via a glutathione-mediated mechanism: implications for aging, stress and TDP-43 proteinopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 906-13. PMID 23325230 DOI: 10.1523/Jneurosci.3314-12.2013  0.372
2013 Walker MP, LaFerla FM, Oddo SS, Brewer GJ. Reversible epigenetic histone modifications and Bdnf expression in neurons with aging and from a mouse model of Alzheimer's disease. Age (Dordrecht, Netherlands). 35: 519-31. PMID 22237558 DOI: 10.1007/s11357-011-9375-5  0.574
2013 Orr M, Oddo S. P1-105: The role of autophagy in Alzheimer's disease Alzheimer's & Dementia. 9: P189-P189. DOI: 10.1016/J.Jalz.2013.05.327  0.416
2013 Oddo S. O2-01-05: The relationship among mTOR, beta-amyloid and tau: Therapeutic implications for Alzheimer's disease Alzheimer's & Dementia. 9: P315-P315. DOI: 10.1016/J.Jalz.2013.04.139  0.475
2012 Yan XX, Cai Y, Shelton J, Deng SH, Luo XG, Oddo S, Laferla FM, Cai H, Rose GM, Patrylo PR. Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice. Plos One. 7: e48782. PMID 23155407 DOI: 10.1371/Journal.Pone.0048782  0.685
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Oddo S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.434
2012 Takamura A, Sato Y, Watabe D, Okamoto Y, Nakata T, Kawarabayashi T, Oddo S, Laferla FM, Shoji M, Matsubara E. Sortilin is required for toxic action of Aβ oligomers (AβOs): extracellular AβOs trigger apoptosis, and intraneuronal AβOs impair degradation pathways. Life Sciences. 91: 1177-86. PMID 22579764 DOI: 10.1016/J.Lfs.2012.04.038  0.647
2012 Cotella D, Hernandez-Enriquez B, Wu X, Li R, Pan Z, Leveille J, Link CD, Oddo S, Sesti F. Toxic role of K+ channel oxidation in mammalian brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4133-44. PMID 22442077 DOI: 10.1523/Jneurosci.6153-11.2012  0.439
2012 Majumder S, Caccamo A, Medina DX, Benavides AD, Javors MA, Kraig E, Strong R, Richardson A, Oddo S. Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling. Aging Cell. 11: 326-35. PMID 22212527 DOI: 10.1111/J.1474-9726.2011.00791.X  0.333
2012 Oddo S. The role of mTOR signaling in Alzheimer disease. Frontiers in Bioscience (Scholar Edition). 4: 941-52. PMID 22202101 DOI: 10.2741/S310  0.502
2012 Caccamo A, Majumder S, Oddo S. Cognitive decline typical of frontotemporal lobar degeneration in transgenic mice expressing the 25-kDa C-terminal fragment of TDP-43. The American Journal of Pathology. 180: 293-302. PMID 22067910 DOI: 10.1016/J.Ajpath.2011.09.022  0.434
2012 Cai Y, Zhang XM, Macklin LN, Cai H, Luo XG, Oddo S, Laferla FM, Struble RG, Rose GM, Patrylo PR, Yan XX. BACE1 elevation is involved in amyloid plaque development in the triple transgenic model of Alzheimer's disease: differential Aβ antibody labeling of early-onset axon terminal pathology. Neurotoxicity Research. 21: 160-74. PMID 21725719 DOI: 10.1007/S12640-011-9256-9  0.615
2012 Edrey Y, Caccamo A, Oddo S, Buffenstein R. P4-283: High levels of BETA-AMYLOID and oxidative stress with no evidence of Alzheimer's disease-like pathology in the longest-lived rodent Alzheimer's & Dementia. 8: S757-S757. DOI: 10.1016/J.Jalz.2013.08.064  0.446
2012 Oddo S. O4-07-05: The role of mTOR in Alzheimer's disease: Lessons from animal models Alzheimer's & Dementia. 8: P628-P628. DOI: 10.1016/J.Jalz.2012.05.1675  0.38
2011 Majumder S, Richardson A, Strong R, Oddo S. Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits. Plos One. 6: e25416. PMID 21980451 DOI: 10.1371/Journal.Pone.0025416  0.562
2011 Bianchi FT, Camera P, Ala U, Imperiale D, Migheli A, Boda E, Tempia F, Berto G, Bosio Y, Oddo S, LaFerla FM, Taraglio S, Dotti CG, Di Cunto F. The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides. Plos One. 6: e22370. PMID 21829458 DOI: 10.1371/Journal.Pone.0022370  0.664
2011 Caccamo A, Maldonado MA, Majumder S, Medina DX, Holbein W, Magrí A, Oddo S. Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism. The Journal of Biological Chemistry. 286: 8924-32. PMID 21266573 DOI: 10.1074/Jbc.M110.180638  0.567
2011 Medina DX, Caccamo A, Oddo S. Methylene blue reduces aβ levels and rescues early cognitive deficit by increasing proteasome activity. Brain Pathology (Zurich, Switzerland). 21: 140-9. PMID 20731659 DOI: 10.1111/J.1750-3639.2010.00430.X  0.541
2010 Caccamo A, Maldonado MA, Bokov AF, Majumder S, Oddo S. CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 22687-92. PMID 21149712 DOI: 10.1073/Pnas.1012851108  0.502
2010 Caccamo A, Magrí A, Oddo S. Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligomers accumulation. Molecular Neurodegeneration. 5: 51. PMID 21070634 DOI: 10.1186/1750-1326-5-51  0.557
2010 Caccamo A, Majumder S, Richardson A, Strong R, Oddo S. Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments. The Journal of Biological Chemistry. 285: 13107-20. PMID 20178983 DOI: 10.1074/Jbc.M110.100420  0.523
2010 Bryleva EY, Rogers MA, Chang CC, Buen F, Harris BT, Rousselet E, Seidah NG, Oddo S, LaFerla FM, Spencer TA, Hickey WF, Chang TY. ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD. Proceedings of the National Academy of Sciences of the United States of America. 107: 3081-6. PMID 20133765 DOI: 10.1073/Pnas.0913828107  0.672
2010 Nakashima AS, Oddo S, Laferla FM, Dyck RH. Experience-dependent regulation of vesicular zinc in male and female 3xTg-AD mice. Neurobiology of Aging. 31: 605-13. PMID 18603329 DOI: 10.1016/J.Neurobiolaging.2008.05.028  0.643
2010 Oddo S. S5-01-04: Molecular interplay between mTOR, Aβ and tau: Effects on cognitive impairments Alzheimer's & Dementia. 6: S167-S167. DOI: 10.1016/J.Jalz.2010.05.519  0.415
2010 Rogers M, Bryleva E, Chang C, Buen F, Harris B, Rousselet E, Seidah N, Oddo S, LaFerla F, Spencer T, Hickey W, Chang TY. P3-285: ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in Alzheimer mice Alzheimer's & Dementia. 6: S535-S535. DOI: 10.1016/J.Jalz.2010.05.1785  0.658
2009 Bourasset F, Ouellet M, Tremblay C, Julien C, Do TM, Oddo S, LaFerla F, Calon F. Reduction of the cerebrovascular volume in a transgenic mouse model of Alzheimer's disease. Neuropharmacology. 56: 808-13. PMID 19705573 DOI: 10.1016/J.Neuropharm.2009.01.006  0.671
2009 Caccamo A, Majumder S, Deng JJ, Bai Y, Thornton FB, Oddo S. Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability. The Journal of Biological Chemistry. 284: 27416-24. PMID 19651785 DOI: 10.1074/Jbc.M109.031278  0.385
2009 Ouellet M, Emond V, Chen CT, Julien C, Bourasset F, Oddo S, LaFerla F, Bazinet RP, Calon F. Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood-brain barrier: An in situ cerebral perfusion study. Neurochemistry International. 55: 476-82. PMID 19442696 DOI: 10.1016/J.Neuint.2009.04.018  0.505
2009 McAlpine FE, Lee JK, Harms AS, Ruhn KA, Blurton-Jones M, Hong J, Das P, Golde TE, LaFerla FM, Oddo S, Blesch A, Tansey MG. Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology. Neurobiology of Disease. 34: 163-77. PMID 19320056 DOI: 10.1016/J.Nbd.2009.01.006  0.776
2009 Nuntagij P, Oddo S, LaFerla FM, Kotchabhakdi N, Ottersen OP, Torp R. Amyloid deposits show complexity and intimate spatial relationship with dendrosomatic plasma membranes: an electron microscopic 3D reconstruction analysis in 3xTg-AD mice and aged canines. Journal of Alzheimer's Disease : Jad. 16: 315-23. PMID 19221421 DOI: 10.3233/Jad-2009-0962  0.654
2009 Guan H, Liu Y, Daily A, Police S, Kim MH, Oddo S, LaFerla FM, Pauly JR, Murphy MP, Hersh LB. Peripherally expressed neprilysin reduces brain amyloid burden: a novel approach for treating Alzheimer's disease. Journal of Neuroscience Research. 87: 1462-73. PMID 19021293 DOI: 10.1002/Jnr.21944  0.655
2009 Gulinello M, Gertner M, Mendoza G, Schoenfeld BP, Oddo S, LaFerla F, Choi CH, McBride SM, Faber DS. Validation of a 2-day water maze protocol in mice. Behavioural Brain Research. 196: 220-7. PMID 18831990 DOI: 10.1016/J.Bbr.2008.09.002  0.568
2009 Oddo S, Caccamo A, Cheng D, LaFerla FM. Genetically altering Abeta distribution from the brain to the vasculature ameliorates tau pathology. Brain Pathology (Zurich, Switzerland). 19: 421-30. PMID 18657136 DOI: 10.1111/J.1750-3639.2008.00194.X  0.688
2009 Nuntagij P, Oddo S, LaFerla FM, Kotchabhakdi N, Ottersen OP, Torp R. P2-139: Amyloid plaques are formed in association with specific plasma membrane domains: An EM-immunogold 3-D-reconstruction study Alzheimer's & Dementia. 5: P302-P302. DOI: 10.1016/J.Jalz.2009.04.450  0.524
2008 Oddo S, Caccamo A, Tseng B, Cheng D, Vasilevko V, Cribbs DH, LaFerla FM. Blocking Abeta42 accumulation delays the onset and progression of tau pathology via the C terminus of heat shock protein70-interacting protein: a mechanistic link between Abeta and tau pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12163-75. PMID 19020010 DOI: 10.1523/Jneurosci.2464-08.2008  0.84
2008 Janelsins MC, Mastrangelo MA, Park KM, Sudol KL, Narrow WC, Oddo S, LaFerla FM, Callahan LM, Federoff HJ, Bowers WJ. Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice. The American Journal of Pathology. 173: 1768-82. PMID 18974297 DOI: 10.2353/Ajpath.2008.080528  0.65
2008 Rodríguez JJ, Jones VC, Tabuchi M, Allan SM, Knight EM, LaFerla FM, Oddo S, Verkhratsky A. Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease. Plos One. 3: e2935. PMID 18698410 DOI: 10.1371/Journal.Pone.0002935  0.699
2008 McKee AC, Carreras I, Hossain L, Ryu H, Klein WL, Oddo S, LaFerla FM, Jenkins BG, Kowall NW, Dedeoglu A. Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain Research. 1207: 225-36. PMID 18374906 DOI: 10.1016/J.Brainres.2008.01.095  0.711
2008 Oddo S. The ubiquitin-proteasome system in Alzheimer's disease. Journal of Cellular and Molecular Medicine. 12: 363-73. PMID 18266959 DOI: 10.1111/J.1582-4934.2008.00276.X  0.546
2008 Lopez JR, Lyckman A, Oddo S, Laferla FM, Querfurth HW, Shtifman A. Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice. Journal of Neurochemistry. 105: 262-71. PMID 18021291 DOI: 10.1111/J.1471-4159.2007.05135.X  0.575
2008 Maezawa I, Hong HS, Liu R, Wu CY, Cheng RH, Kung MP, Kung HF, Lam KS, Oddo S, Laferla FM, Jin LW. Congo red and thioflavin-T analogs detect Abeta oligomers. Journal of Neurochemistry. 104: 457-68. PMID 17953662 DOI: 10.1111/J.1471-4159.2007.04972.X  0.62
2008 Oddo S, Caccamo A, Tseng B, Cheng D, Vasilevko V, Cribbs DH, LaFerla FM. O2-02-06: Blocking Aβ42 accumulation delays the onset and progression of Tau pathology and cognitive decline via CHIP: A mechanistic link between Aβ and Tau pathology Alzheimer's & Dementia. 4: T134-T134. DOI: 10.1016/J.Jalz.2008.05.318  0.649
2008 Coakley MF, Moloney AM, Oddo S, LaFerla FM, O' Neill C. P4-251: Changes in Akt and IGF-1 receptor signaling relate to developing Abeta and tangle pathology in the triple transgenic model of Alzheimer's disease Alzheimer's & Dementia. 4: T745-T745. DOI: 10.1016/J.Jalz.2008.05.2320  0.638
2008 Liu Y, Guan H, Klein RL, Oddo S, LaFerla FM, Murphy MP, Hersh LB. P2-343: Peripherally overexpessed neprilysin in muscle reduces brain amyloid in a transgenic mouse model of AD Alzheimer's & Dementia. 4: T473-T473. DOI: 10.1016/J.Jalz.2008.05.1420  0.5
2007 Carroll JC, Rosario ER, Chang L, Stanczyk FZ, Oddo S, LaFerla FM, Pike CJ. Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13357-65. PMID 18045930 DOI: 10.1523/Jneurosci.2718-07.2007  0.682
2007 Yamasaki TR, Blurton-Jones M, Morrissette DA, Kitazawa M, Oddo S, LaFerla FM. Neural stem cells improve memory in an inducible mouse model of neuronal loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11925-33. PMID 17978032 DOI: 10.1523/Jneurosci.1627-07.2007  0.738
2007 Cole AR, Noble W, van Aalten L, Plattner F, Meimaridou R, Hogan D, Taylor M, LaFrancois J, Gunn-Moore F, Verkhratsky A, Oddo S, LaFerla F, Giese KP, Dineley KT, Duff K, et al. Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression. Journal of Neurochemistry. 103: 1132-44. PMID 17683481 DOI: 10.1111/J.1471-4159.2007.04829.X  0.696
2007 Clinton LK, Billings LM, Green KN, Caccamo A, Ngo J, Oddo S, McGaugh JL, LaFerla FM. Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice. Neurobiology of Disease. 28: 76-82. PMID 17659878 DOI: 10.1016/J.Nbd.2007.06.013  0.79
2007 LaFerla FM, Green KN, Oddo S. Intracellular amyloid-beta in Alzheimer's disease. Nature Reviews. Neuroscience. 8: 499-509. PMID 17551515 DOI: 10.1038/Nrn2168  0.727
2007 Oddo S, Caccamo A, Cheng D, Jouleh B, Torp R, LaFerla FM. Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice. Journal of Neurochemistry. 102: 1053-63. PMID 17472708 DOI: 10.1111/J.1471-4159.2007.04607.X  0.711
2007 Caccamo A, Oddo S, Tran LX, LaFerla FM. Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles. The American Journal of Pathology. 170: 1669-75. PMID 17456772 DOI: 10.2353/Ajpath.2007.061178  0.647
2007 Stutzmann GE, Smith I, Caccamo A, Oddo S, Parker I, Laferla F. Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models. Annals of the New York Academy of Sciences. 1097: 265-77. PMID 17413028 DOI: 10.1196/Annals.1379.025  0.575
2007 Giménez-Llort L, Blázquez G, Cañete T, Johansson B, Oddo S, Tobeña A, LaFerla FM, Fernández-Teruel A. Modeling behavioral and neuronal symptoms of Alzheimer's disease in mice: a role for intraneuronal amyloid. Neuroscience and Biobehavioral Reviews. 31: 125-47. PMID 17055579 DOI: 10.1016/J.Neubiorev.2006.07.007  0.721
2006 Rosario ER, Carroll JC, Oddo S, LaFerla FM, Pike CJ. Androgens regulate the development of neuropathology in a triple transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13384-9. PMID 17182789 DOI: 10.1523/Jneurosci.2514-06.2006  0.709
2006 Oddo S, Vasilevko V, Caccamo A, Kitazawa M, Cribbs DH, LaFerla FM. Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles. The Journal of Biological Chemistry. 281: 39413-23. PMID 17056594 DOI: 10.1074/Jbc.M608485200  0.705
2006 Stutzmann GE, Smith I, Caccamo A, Oddo S, Laferla FM, Parker I. Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5180-9. PMID 16687509 DOI: 10.1523/Jneurosci.0739-06.2006  0.627
2006 Caccamo A, Oddo S, Billings LM, Green KN, Martinez-Coria H, Fisher A, LaFerla FM. M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron. 49: 671-82. PMID 16504943 DOI: 10.1016/J.Neuron.2006.01.020  0.743
2006 Oddo S, LaFerla FM. The role of nicotinic acetylcholine receptors in Alzheimer's disease. Journal of Physiology, Paris. 99: 172-9. PMID 16448808 DOI: 10.1016/J.Jphysparis.2005.12.080  0.695
2006 Oddo S, Caccamo A, Smith IF, Green KN, LaFerla FM. A dynamic relationship between intracellular and extracellular pools of Abeta. The American Journal of Pathology. 168: 184-94. PMID 16400022 DOI: 10.2353/Ajpath.2006.050593  0.738
2006 Oddo S, Caccamo A, Tran L, Lambert MP, Glabe CG, Klein WL, LaFerla FM. Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology. The Journal of Biological Chemistry. 281: 1599-604. PMID 16282321 DOI: 10.1074/Jbc.M507892200  0.7
2006 Janelsins MC, Mastrangelo MA, Park KM, Fowlkes KL, Kinsky M, Narrow WC, Oddo S, LaFerla FM, Federoff HJ, Bowers WJ. 248. Revealing the Role(s) of TNF-alpha in Early Alzheimer's Disease Via rAAV-Mediated Hippocampal Gene Transfer in a Triple Transgenic Mouse Model Molecular Therapy. 13: S95. DOI: 10.1016/J.Ymthe.2006.08.275  0.671
2006 Caccamo A, Oddo S, Fisher A, LaFerla FM. P1-451: M1 receptors play a central role in modulating AD-like pathology in transgenic mice Alzheimer's & Dementia. 2: S230-S230. DOI: 10.1016/J.Jalz.2006.05.830  0.619
2006 Rosario ER, Carroll JC, Chang L, Stanczyk F, Oddo S, LaFerla F, Pike CJ. P1-252: Androgens regulate development of neuropathology in a mouse model of Alzheimer's disease Alzheimer's & Dementia. 2: S170-S170. DOI: 10.1016/J.Jalz.2006.05.629  0.611
2006 Stutzmann GE, Smith I, Caccamo A, Oddo S, LaFerla F, Parker I. P1-125: Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult and aged Alzheimer disease mice Alzheimer's & Dementia. 2: S132-S132. DOI: 10.1016/J.Jalz.2006.05.501  0.592
2006 Gimenez-Llort L, Blazquez G, Canete T, Rosa R, Vivo M, Oddo S, Navarro X, LaFerla FM, Johansson B, Tobena A, Fernandez-Teruel A. P1-124: Modeling neuropsychiatric symptoms of Alzheimer's dementia in 3xTgAD mice Alzheimer's & Dementia. 2: S132-S132. DOI: 10.1016/J.Jalz.2006.05.500  0.431
2006 Fisher A, Caccamo A, Oddo S, Billings LM, Green KN, Brandeis R, Pittel Z, Barner N, Elkon H, Laferla FM. S4-04-02: M1 muscarinic agonists as a comprehensive therapy in Alzheimer's disease Alzheimer's & Dementia. 2: S73-S73. DOI: 10.1016/J.Jalz.2006.05.285  0.525
2006 Hersh LB, Guan H, Daily A, Murphy MP, Oddo S, LaFerla FM. O2-05-01: Peripheral expression of neprilysin decreases amyloid deposition in hAPP mice Alzheimer's & Dementia. 2: S39-S40. DOI: 10.1016/J.Jalz.2006.05.138  0.592
2006 Oddo S, Caccamo A, Vasilevko V, Cribbs DH, LaFerla FM. O1-06-04: Reduction of both soluble Aβ and tau, but not soluble Aβ alone, ameliorates cognitive decline in transgenic mice with plaques and tangles Alzheimer's & Dementia. 2: S21-S21. DOI: 10.1016/J.Jalz.2006.05.064  0.67
2005 Janelsins MC, Mastrangelo MA, Oddo S, LaFerla FM, Federoff HJ, Bowers WJ. Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. Journal of Neuroinflammation. 2: 23. PMID 16232318 DOI: 10.1186/1742-2094-2-23  0.706
2005 Kitazawa M, Oddo S, Yamasaki TR, Green KN, LaFerla FM. Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8843-53. PMID 16192374 DOI: 10.1523/Jneurosci.2868-05.2005  0.828
2005 Smith IF, Hitt B, Green KN, Oddo S, LaFerla FM. Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease. Journal of Neurochemistry. 94: 1711-8. PMID 16156741 DOI: 10.1111/J.1471-4159.2005.03332.X  0.698
2005 LaFerla FM, Oddo S. Alzheimer's disease: Abeta, tau and synaptic dysfunction. Trends in Molecular Medicine. 11: 170-6. PMID 15823755 DOI: 10.1016/J.Molmed.2005.02.009  0.687
2005 Billings LM, Oddo S, Green KN, McGaugh JL, LaFerla FM. Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron. 45: 675-88. PMID 15748844 DOI: 10.1016/J.Neuron.2005.01.040  0.719
2005 Caccamo A, Oddo S, Sugarman MC, Akbari Y, LaFerla FM. Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders. Neurobiology of Aging. 26: 645-54. PMID 15708439 DOI: 10.1016/J.Neurobiolaging.2004.06.013  0.791
2005 Oddo S, Caccamo A, Green KN, Liang K, Tran L, Chen Y, Leslie FM, LaFerla FM. Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 3046-51. PMID 15705720 DOI: 10.1073/Pnas.0408500102  0.739
2004 Oddo S, Billings L, Kesslak JP, Cribbs DH, LaFerla FM. Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron. 43: 321-32. PMID 15294141 DOI: 10.1016/J.Neuron.2004.07.003  0.694
2004 Rissman RA, Poon WW, Blurton-Jones M, Oddo S, Torp R, Vitek MP, LaFerla FM, Rohn TT, Cotman CW. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. The Journal of Clinical Investigation. 114: 121-30. PMID 15232619 DOI: 10.1172/Jci20640  0.799
2004 Shakkottai VG, Chou CH, Oddo S, Sailer CA, Knaus HG, Gutman GA, Barish ME, LaFerla FM, Chandy KG. Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia. The Journal of Clinical Investigation. 113: 582-90. PMID 14966567 DOI: 10.1172/Jci200420216  0.54
2004 Agadjanyan MG, Petrushina I, Ghochikyan A, Vasilevko V, Movsesyan N, Oddo S, LaFerla FM, Cribbs DH. P4-385 Alzheimer's epitope vaccine based on the dominant B cell epitope of Aβ and padre, a foreign T cell epitope Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81943-2  0.346
2004 Oddo S, Billings LM, LaFerla FM. P4-371 In vivo evidence linking Aβ and TAU Neurobiology of Aging. 25: S580. DOI: 10.1016/S0197-4580(04)81929-8  0.635
2004 Smith IF, Oddo S, Green KN, LaFerla FM. P2-119 Alterations of intracellular CA2+ homeostasis in a triple transgenic model (PS1M146V, APPSWE, TAUP301L) of Alzheimer's disease Neurobiology of Aging. 25: S258. DOI: 10.1016/S0197-4580(04)80866-2  0.683
2004 Billings LM, Oddo S, LaFerla FM. P2-073 Assessing cognitive impairments in the 3XTG-AD mice: correlations with plaque and tangle pathology Neurobiology of Aging. 25: S244-S245. DOI: 10.1016/S0197-4580(04)80820-0  0.649
2004 Furukawa K, Wang Y, Yao PJ, Mattson MP, Oddo S, LaFerla FM. P2-071 Ion channel properties of neurons from APP/PS1/TAU triple mutant mice Neurobiology of Aging. 25: S244. DOI: 10.1016/S0197-4580(04)80818-2  0.563
2004 Akbari Y, Dagher N, Murphy MP, Kozak JA, Hitt B, Oddo S, Tseng B, Golde TE, Cahalan M, Leissring MA, M. LaFerla F. P1-206 Capacitative and non-capacitative Ca2+ entry modulate Aβ levels Neurobiology of Aging. 25: S154-S155. DOI: 10.1016/S0197-4580(04)80519-0  0.766
2004 LaFerla FM, Oddo S, Billings LM. O1-04-08 Antibody-mediated clearance of beta-amyloid reverses early TAU aggregates, but not late, hyperphosphorylated TAU Neurobiology of Aging. 25: S18. DOI: 10.1016/S0197-4580(04)80059-9  0.605
2003 Oddo S, Caccamo A, Kitazawa M, Tseng BP, LaFerla FM. Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiology of Aging. 24: 1063-70. PMID 14643377 DOI: 10.1016/J.Neurobiolaging.2003.08.012  0.853
2003 Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron. 39: 409-21. PMID 12895417 DOI: 10.1016/S0896-6273(03)00434-3  0.823
2002 Sugarman MC, Yamasaki TR, Oddo S, Echegoyen JC, Murphy MP, Golde TE, Jannatipour M, Leissring MA, LaFerla FM. Inclusion body myositis-like phenotype induced by transgenic overexpression of beta APP in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 99: 6334-9. PMID 11972038 DOI: 10.1073/Pnas.082545599  0.79
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