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Damian Houde, Ph.D. - Publications

Affiliations: 
2010 Chemistry Northeastern University, Boston, MA, United States 
Area:
Bioanalytical chemistry, mass spectrometry, hydrogen/deuterium exchange
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Code C, Qiu D, Solov'yov IA, Lee JG, Shin HC, Roland C, Sagui C, Houde D, Rand KD, Jørgensen TJD. Conformationally Restricted Glycopeptide Backbone Inhibits Gas-Phase H/D Scrambling between Glycan and Peptide Moieties. Journal of the American Chemical Society. PMID 37883679 DOI: 10.1021/jacs.3c04068  0.329
2021 Dooley K, McConnell RE, Xu K, Lewis ND, Haupt S, Youniss MR, Martin S, Sia CL, McCoy C, Moniz RJ, Burenkova O, Sanchez-Salazar J, Jang SC, Choi B, Harrison RA, ... Houde D, et al. A Versatile Platform for Generating Engineered Extracellular Vesicles with Defined Therapeutic Properties. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33484965 DOI: 10.1016/j.ymthe.2021.01.020  0.634
2019 Masson GR, Burke JE, Ahn NG, Anand GS, Borchers C, Brier S, Bou-Assaf GM, Engen JR, Englander SW, Faber J, Garlish R, Griffin PR, Gross ML, Guttman M, Hamuro Y, ... ... Houde D, et al. Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments. Nature Methods. 16: 595-602. PMID 31249422 DOI: 10.1038/S41592-019-0459-Y  0.562
2018 Pawlowski JW, Bajardi-Taccioli A, Houde D, Feschenko M, Carlage T, Kaltashov IA. Influence of glycan modification on IgG1 biochemical and biophysical properties. Journal of Pharmaceutical and Biomedical Analysis. 151: 133-144. PMID 29324282 DOI: 10.1016/J.Jpba.2017.12.061  0.427
2018 Muneeruddin K, Bobst CE, Frenkel R, Houde D, Turyan I, Sosic Z, Kaltashov IA. Characterization of a PEGylated protein therapeutic by ion exchange chromatography with on-line detection by native ESI MS and MS/MS. The Analyst. 142: 336-344. PMID 27965993 DOI: 10.1039/C6An02041K  0.429
2017 Chen TF, Sazinsky SL, Houde D, DiLillo DJ, Bird J, Li KK, Cheng GT, Qiu H, Engen JR, Ravetch JV, Wittrup KD. Engineering Aglycosylated IgG Variants with Wild-type or Improved Binding Affinity to Human Fc gamma RIIA and Fc gamma RIIIAs. Journal of Molecular Biology. PMID 28694069 DOI: 10.1016/J.Jmb.2017.07.001  0.556
2016 Weiss WF, Gabrielson JP, Al-Azzam W, Chen G, Davis DL, Das TK, Hayes DB, Houde D, Singh SK. Technical Decision Making With Higher Order Structure Data: Perspectives on Higher Order Structure Characterization From the Biopharmaceutical Industry. Journal of Pharmaceutical Sciences. PMID 27743675 DOI: 10.1016/J.Xphs.2016.09.003  0.307
2016 Inouye H, Houde D, Temel DB, Makowski L. Utility of Solution X-ray Scattering for the Development of Antibody Biopharmaceuticals. Journal of Pharmaceutical Sciences. PMID 27637321 DOI: 10.1016/J.Xphs.2016.07.021  0.314
2016 E Nazari Z, van de Weert M, Bou-Assaf G, Houde D, Weiskopf A, D Rand K. Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry. Journal of Pharmaceutical Sciences. PMID 27578543 DOI: 10.1016/J.Xphs.2016.07.006  0.444
2016 Danwen Q, Code C, Quan C, Gong BJ, Arndt J, Pepinsky B, Rand KD, Houde D. Investigating the Role of Artemin Glycosylation. Pharmaceutical Research. PMID 26908049 DOI: 10.1007/S11095-016-1880-X  0.363
2016 Houde D, Nazari ZE, Bou-Assaf GM, Weiskopf AS, Rand KD. Conformational Analysis of Proteins in Highly Concentrated Solutions by Dialysis-Coupled Hydrogen/Deuterium Exchange Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 26860088 DOI: 10.1007/S13361-015-1331-7  0.477
2015 Wei JY, Bou-Assaf GM, Houde D, Weiskopf A. Technical Decision-Making with Higher Order Structure Data: Detecting Reversible Concentration-Dependent Self-Association in a Monoclonal Antibody and a Preliminary Investigation to Eliminate It. Journal of Pharmaceutical Sciences. PMID 26308556 DOI: 10.1002/Jps.24616  0.373
2013 Iacob RE, Bou-Assaf GM, Makowski L, Engen JR, Berkowitz SA, Houde D. Investigating monoclonal antibody aggregation using a combination of H/DX-MS and other biophysical measurements. Journal of Pharmaceutical Sciences. 102: 4315-29. PMID 24136070 DOI: 10.1002/Jps.23754  0.586
2013 Houde D, Engen JR. Conformational analysis of recombinant monoclonal antibodies with hydrogen/deuterium exchange mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 988: 269-89. PMID 23475726 DOI: 10.1007/978-1-62703-327-5_17  0.644
2012 Houde D, Berkowitz SA. Conformational comparability of factor IX-Fc fusion protein, factor IX, and purified Fc fragment in the absence and presence of calcium. Journal of Pharmaceutical Sciences. 101: 1688-700. PMID 22271461 DOI: 10.1002/Jps.23064  0.441
2011 Houde D, Demarest SJ. Fine details of IGF-1R activation, inhibition, and asymmetry determined by associated hydrogen /deuterium-exchange and peptide mass mapping. Structure (London, England : 1993). 19: 890-900. PMID 21645859 DOI: 10.1016/J.Str.2011.03.014  0.347
2011 Houde D, Berkowitz SA, Engen JR. The utility of hydrogen/deuterium exchange mass spectrometry in biopharmaceutical comparability studies. Journal of Pharmaceutical Sciences. 100: 2071-86. PMID 21491437 DOI: 10.1002/Jps.22432  0.616
2010 Aono H, Wen D, Zang L, Houde D, Pepinsky RB, Evans DR. Efficient on-column conversion of IgG1 trisulfide linkages to native disulfides in tandem with Protein A affinity chromatography. Journal of Chromatography. A. 1217: 5225-32. PMID 20598700 DOI: 10.1016/J.Chroma.2010.06.029  0.462
2010 Houde D, Peng Y, Berkowitz SA, Engen JR. Post-translational modifications differentially affect IgG1 conformation and receptor binding. Molecular & Cellular Proteomics : McP. 9: 1716-28. PMID 20103567 DOI: 10.1074/Mcp.M900540-Mcp200  0.626
2010 Kaltashov IA, Bobst CE, Abzalimov RR, Berkowitz SA, Houde D. Conformation and dynamics of biopharmaceuticals: transition of mass spectrometry-based tools from academe to industry. Journal of the American Society For Mass Spectrometry. 21: 323-37. PMID 19963397 DOI: 10.1016/J.Jasms.2009.10.013  0.42
2009 Houde D, Arndt J, Domeier W, Berkowitz S, Engen JR. Characterization of IgG1 Conformation and Conformational Dynamics by Hydrogen/Deuterium Exchange Mass Spectrometry. Analytical Chemistry. 81: 5966. PMID 19606834 DOI: 10.1021/ac9009287  0.556
2009 Houde D, Arndt J, Domeier W, Berkowitz S, Engen JR. Characterization of IgG1 conformation and conformational dynamics by hydrogen/deuterium exchange mass spectrometry. Analytical Chemistry. 81: 2644-51. PMID 19265386 DOI: 10.1021/Ac802575Y  0.66
2009 Houde D, Engen JR. Conformational dynamics of proteins By mass spectrometry hydrogen/deuterium exchange and covalent labelling approaches Chimica Oggi. 27: XII-XV.  0.558
2008 Sosic Z, Houde D, Blum A, Carlage T, Lyubarskaya Y. Application of imaging capillary IEF for characterization and quantitative analysis of recombinant protein charge heterogeneity. Electrophoresis. 29: 4368-76. PMID 19016565 DOI: 10.1002/Elps.200800157  0.408
2008 Bobst CE, Abzalimov RR, Houde D, Kloczewiak M, Mhatre R, Berkowitz SA, Kaltashov IA. Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches. Analytical Chemistry. 80: 7473-81. PMID 18729476 DOI: 10.1021/Ac801214X  0.473
2006 Houde D, Kauppinen P, Mhatre R, Lyubarskaya Y. Determination of protein oxidation by mass spectrometry and method transfer to quality control. Journal of Chromatography. A. 1123: 189-98. PMID 16716331 DOI: 10.1016/J.Chroma.2006.04.046  0.386
2006 Siemiatkoski J, Lyubarskaya Y, Houde D, Tep S, Mhatre R. A comparison of three techniques for quantitative carbohydrate analysis used in characterization of therapeutic antibodies. Carbohydrate Research. 341: 410-9. PMID 16378604 DOI: 10.1016/J.Carres.2005.11.024  0.393
2006 Lyubarskaya Y, Houde D, Woodard J, Murphy D, Mhatre R. Analysis of recombinant monoclonal antibody isoforms by electrospray ionization mass spectrometry as a strategy for streamlining characterization of recombinant monoclonal antibody charge heterogeneity. Analytical Biochemistry. 348: 24-39. PMID 16289440 DOI: 10.1016/J.Ab.2005.10.003  0.445
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