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Brian O. Diekman, Ph.D. - Publications

Affiliations: 
2012 Biomedical Engineering Duke University, Durham, NC 
Area:
Biomedical, General, Biomechanics
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Copp ME, Flanders MC, Gagliardi R, Gilbertie JM, Sessions GA, Chubinskaya S, Loeser RF, Schnabel LV, Diekman BO. The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence. Osteoarthritis and Cartilage. PMID 33227437 DOI: 10.1016/j.joca.2020.11.004  0.353
2020 Coryell PR, Diekman BO, Loeser RF. Mechanisms and therapeutic implications of cellular senescence in osteoarthritis. Nature Reviews. Rheumatology. PMID 33208917 DOI: 10.1038/s41584-020-00533-7  0.402
2020 Tessier S, Doolittle AC, Sao K, Rotty JD, Bear JE, Ulici V, Loeser RF, Shapiro IM, Diekman BO, Risbud MV. Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation. Jci Insight. PMID 31961823 DOI: 10.1172/Jci.Insight.131382  0.415
2019 D'Costa S, Rich MJ, Diekman BO. Engineered cartilage from human chondrocytes with homozygous knockout of cell cycle inhibitor p21. Tissue Engineering. Part A. PMID 31642391 DOI: 10.1089/Ten.Tea.2019.0214  0.489
2019 Sessions GA, Copp ME, Liu JY, Sinkler MA, D'Costa S, Diekman BO. Controlled induction and targeted elimination of p16-expressing chondrocytes in cartilage explant culture. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900815RR. PMID 31408372 DOI: 10.1096/Fj.201900815Rr  0.473
2019 Novais EM, Diekman BO, Shapiro IM, Risbud MV. p16 deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 30811968 DOI: 10.1016/J.Matbio.2019.02.004  0.394
2019 Liu JY, Souroullas GP, Diekman BO, Krishnamurthy J, Hall BM, Sorrentino JA, Parker JS, Sessions GA, Gudkov AV, Sharpless NE. Cells exhibiting strong promoter activation in vivo display features of senescence. Proceedings of the National Academy of Sciences of the United States of America. PMID 30683717 DOI: 10.1073/Pnas.1818313116  0.436
2019 Sessions GA, Sinkler MA, Copp ME, Diekman BO. Controlled induction and targeted elimination of P16INK4A-high chondrocytes to investigate senescence-mediated cartilage dysfunction Osteoarthritis and Cartilage. 27. DOI: 10.1016/J.Joca.2019.02.140  0.317
2018 Diekman BO, Sessions GA, Collins JA, Knecht AK, Strum SL, Mitin NK, Carlson CS, Loeser RF, Sharpless NE. Expression of p16 is a biomarker of chondrocyte aging but does not cause osteoarthritis. Aging Cell. e12771. PMID 29744983 DOI: 10.1111/Acel.12771  0.38
2017 Diekman B, Rotty J, Ulici V, Bear J, Loeser R, Sharpless N. Chondrocyte-Specific Loss of the Branched Actin Mediator ARP2/3 Results in Growth Plate Fusion and Proteoglycan Loss in Articular Cartilage Osteoarthritis and Cartilage. 25: S277-S278. DOI: 10.1016/J.Joca.2017.02.469  0.307
2016 Loeser RF, Collins JA, Diekman BO. Ageing and the pathogenesis of osteoarthritis. Nature Reviews. Rheumatology. PMID 27192932 DOI: 10.1038/Nrrheum.2016.65  0.396
2015 Diekman BO, Thakore PI, O'Connor SK, Willard VP, Brunger JM, Christoforou N, Leong KW, Gersbach CA, Guilak F. Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. Tissue Engineering. Part A. 21: 1261-74. PMID 25517798 DOI: 10.1089/Ten.Tea.2014.0240  0.8
2015 Guilak F, Diekman BO, Olson SA. Stem cell therapies for post-traumatic arthritis Post-Traumatic Arthritis: Pathogenesis, Diagnosis and Management. 343-348. DOI: 10.1007/978-1-4899-7606-2_27  0.635
2014 Willard VP, Diekman BO, Sanchez-Adams J, Christoforou N, Leong KW, Guilak F. Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening. Arthritis & Rheumatology (Hoboken, N.J.). 66: 3062-72. PMID 25047145 DOI: 10.1002/Art.38780  0.768
2013 Diekman BO, Guilak F. Stem cell-based therapies for osteoarthritis: challenges and opportunities. Current Opinion in Rheumatology. 25: 119-26. PMID 23190869 DOI: 10.1097/Bor.0B013E32835Aa28D  0.738
2013 Wu CL, Diekman BO, Jain D, Guilak F. Diet-induced obesity alters the differentiation potential of stem cells isolated from bone marrow, adipose tissue and infrapatellar fat pad: the effects of free fatty acids. International Journal of Obesity (2005). 37: 1079-87. PMID 23164698 DOI: 10.1038/Ijo.2012.171  0.788
2013 Diekman BO, Wu CL, Louer CR, Furman BD, Huebner JL, Kraus VB, Olson SA, Guilak F. Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis. Cell Transplantation. 22: 1395-408. PMID 22889498 DOI: 10.3727/096368912X653264  0.789
2013 Willard V, Diekman B, Sanchez-Adams J, O'Connor S, Christoforou N, Leong K, Guilak F. Osteoarthritis in a dish: the effects of pro-inflammatory cytokines on cartilage derived from induced pluripotent stem cells Osteoarthritis and Cartilage. 21: S281-S282. DOI: 10.1016/J.Joca.2013.02.590  0.808
2012 Diekman BO, Christoforou N, Willard VP, Sun H, Sanchez-Adams J, Leong KW, Guilak F. Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 19172-7. PMID 23115336 DOI: 10.1073/Pnas.1210422109  0.795
2011 Diekman B, Wu C, Louer C, Furman B, Huebner J, Kraus V, Olson S, Guilak F. 1-17 INTRA-ARTICULAR INJECTION OF PURIFIED MESENCHYMAL STEM CELLS FROM C57BL/6 OR MRL/MPJ “SUPERHEALER” MICE PREVENTS POSTTRAUMATIC ARTHRITIS Osteoarthritis and Cartilage. 19: S5. DOI: 10.1016/S1063-4584(11)60023-X  0.775
2010 Guilak F, Estes BT, Diekman BO, Moutos FT, Gimble JM. 2010 Nicolas Andry Award: Multipotent adult stem cells from adipose tissue for musculoskeletal tissue engineering. Clinical Orthopaedics and Related Research. 468: 2530-40. PMID 20625952 DOI: 10.1007/S11999-010-1410-9  0.82
2010 Estes BT, Diekman BO, Gimble JM, Guilak F. Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype. Nature Protocols. 5: 1294-311. PMID 20595958 DOI: 10.1038/Nprot.2010.81  0.834
2010 Valonen PK, Moutos FT, Kusanagi A, Moretti MG, Diekman BO, Welter JF, Caplan AI, Guilak F, Freed LE. In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly(epsilon-caprolactone) scaffolds. Biomaterials. 31: 2193-200. PMID 20034665 DOI: 10.1016/J.Biomaterials.2009.11.092  0.784
2010 Diekman BO, Estes BT, Guilak F. The effects of BMP6 overexpression on adipose stem cell chondrogenesis: Interactions with dexamethasone and exogenous growth factors. Journal of Biomedical Materials Research. Part A. 93: 994-1003. PMID 19722282 DOI: 10.1002/Jbm.A.32589  0.763
2010 Diekman BO, Rowland CR, Lennon DP, Caplan AI, Guilak F. Chondrogenesis of adult stem cells from adipose tissue and bone marrow: induction by growth factors and cartilage-derived matrix. Tissue Engineering. Part A. 16: 523-33. PMID 19715387 DOI: 10.1089/Ten.Tea.2009.0398  0.823
2008 Estes BT, Diekman BO, Guilak F. Monolayer cell expansion conditions affect the chondrogenic potential of adipose-derived stem cells. Biotechnology and Bioengineering. 99: 986-95. PMID 17929321 DOI: 10.1002/Bit.21662  0.795
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