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Jeremy E. Purvis, Ph.D. - Publications

Affiliations: 
2009 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Biomedical Engineering
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ranek JS, Stallaert W, Milner JJ, Redick M, Wolff SC, Beltran AS, Stanley N, Purvis JE. DELVE: feature selection for preserving biological trajectories in single-cell data. Nature Communications. 15: 2765. PMID 38553455 DOI: 10.1038/s41467-024-46773-z  0.747
2024 Zikry TM, Wolff SC, Ranek JS, Davis HM, Naugle A, Luthra N, Whitman AA, Kedziora KM, Stallaert W, Kosorok MR, Spanheimer PM, Purvis JE. Cell cycle plasticity underlies fractional resistance to palbociclib in ER+/HER2- breast tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 121: e2309261121. PMID 38324568 DOI: 10.1073/pnas.2309261121  0.737
2023 Ranek JS, Stallaert W, Milner J, Stanley N, Purvis JE. Feature selection for preserving biological trajectories in single-cell data. Biorxiv : the Preprint Server For Biology. PMID 37214963 DOI: 10.1101/2023.05.09.540043  0.746
2022 Stallaert W, Taylor SR, Kedziora KM, Taylor CD, Sobon HK, Young CL, Limas JC, Varblow Holloway J, Johnson MS, Cook JG, Purvis JE. The molecular architecture of cell cycle arrest. Molecular Systems Biology. 18: e11087. PMID 36161508 DOI: 10.15252/msb.202211087  0.747
2022 Ranek JS, Stanley N, Purvis JE. Integrating temporal single-cell gene expression modalities for trajectory inference and disease prediction. Genome Biology. 23: 186. PMID 36064614 DOI: 10.1186/s13059-022-02749-0  0.302
2022 Stallaert W, Kedziora KM, Taylor CD, Zikry TM, Ranek JS, Sobon HK, Taylor SR, Young CL, Cook JG, Purvis JE. The structure of the human cell cycle. Cell Systems. 13: 103. PMID 35051372 DOI: 10.1016/j.cels.2021.12.006  0.735
2021 Enrico TP, Stallaert W, Wick ET, Ngoi P, Wang X, Rubin SM, Brown NG, Purvis J, Emanuele MJ. Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2. Elife. 10. PMID 34851822 DOI: 10.7554/eLife.70691  0.724
2021 Stallaert W, Kedziora KM, Taylor CD, Zikry TM, Ranek JS, Sobon HK, Taylor SR, Young CL, Cook JG, Purvis JE. The structure of the human cell cycle. Cell Systems. PMID 34800361 DOI: 10.1016/j.cels.2021.10.007  0.735
2021 Haggerty RA, Purvis JE. Inferring the structures of signaling motifs from paired dynamic traces of single cells. Plos Computational Biology. 17: e1008657. PMID 33539338 DOI: 10.1371/journal.pcbi.1008657  0.317
2019 Stallaert W, Kedziora KM, Chao HX, Purvis JE. Bistable switches as integrators and actuators during cell cycle progression. Febs Letters. PMID 31566708 DOI: 10.1002/1873-3468.13628  0.738
2019 Chao HX, Fakhreddin RI, Shimerov HK, Kedziora KM, Kumar RJ, Perez J, Limas JC, Grant GD, Cook JG, Gupta GP, Purvis JE. Evidence that the human cell cycle is a series of uncoupled, memoryless phases. Molecular Systems Biology. 15: e8604. PMID 30886052 DOI: 10.15252/Msb.20188604  0.363
2018 Grant GD, Kedziora KM, Limas JC, Cook JG, Purvis JE. Accurate delineation of cell cycle phase transitions in living cells with PIP-FUCCI. Cell Cycle (Georgetown, Tex.). PMID 30421640 DOI: 10.1080/15384101.2018.1547001  0.4
2018 Wolff SC, Kedziora KM, Dumitru R, Dungee CD, Zikry TM, Beltran AS, Haggerty RA, Cheng J, Redick MA, Purvis JE. Inheritance of OCT4 predetermines fate choice in human embryonic stem cells. Molecular Systems Biology. 14: e8140. PMID 30177503 DOI: 10.15252/Msb.20178140  0.428
2018 Borland D, Yi H, Grant GD, Kedziora KM, Chao HX, Haggerty RA, Kumar J, Wolff SC, Cook JG, Purvis JE. The Cell Cycle Browser: An Interactive Tool for Visualizing, Simulating, and Perturbing Cell-Cycle Progression. Cell Systems. PMID 30077635 DOI: 10.1016/J.Cels.2018.06.004  0.455
2017 Matson JP, Dumitru R, Coryell P, Baxley RM, Chen W, Twaroski K, Webber BR, Tolar J, Bielinsky AK, Purvis JE, Cook JG. Rapid DNA replication origin licensing protects stem cell pluripotency. Elife. 6. PMID 29148972 DOI: 10.7554/Elife.30473  0.359
2017 Chao HX, Poovey CE, Privette AA, Grant GD, Chao HY, Cook JG, Purvis JE. Orchestration of DNA Damage Checkpoint Dynamics across the Human Cell Cycle. Cell Systems. PMID 29102360 DOI: 10.1016/J.Cels.2017.09.015  0.364
2017 Kedziora KM, Purvis JE. Cell biology: The persistence of memory. Nature. PMID 28869963 DOI: 10.1038/Nature23549  0.395
2017 Matson JP, Dumitru R, Coryell P, Baxley RM, Chen W, Twaroski K, Webber BR, Tolar J, Bielinsky A, Purvis JE, Cook JG. Author response: Rapid DNA replication origin licensing protects stem cell pluripotency Elife. DOI: 10.7554/Elife.30473.025  0.302
2015 Coleman KE, Grant GD, Haggerty RA, Brantley K, Shibata E, Workman BD, Dutta A, Varma D, Purvis JE, Cook JG. Sequential replication-coupled destruction at G1/S ensures genome stability. Genes & Development. 29: 1734-46. PMID 26272819 DOI: 10.1101/Gad.263731.115  0.378
2015 Davis DM, Purvis JE. Computational analysis of signaling patterns in single cells. Seminars in Cell & Developmental Biology. 37: 35-43. PMID 25263011 DOI: 10.1016/J.Semcdb.2014.09.015  0.42
2014 Gorman BR, Lu J, Baccei A, Lowry NC, Purvis JE, Mangoubi RS, Lerou PH. Multi-scale imaging and informatics pipeline for in situ pluripotent stem cell analysis. Plos One. 9: e116037. PMID 25551762 DOI: 10.1371/Journal.Pone.0116037  0.438
2013 Diamond SL, Purvis J, Chatterjee M, Flamm MH. Systems biology of platelet-vessel wall interactions. Frontiers in Physiology. 4: 229. PMID 23986721 DOI: 10.3389/Fphys.2013.00229  0.702
2013 Purvis JE, Lahav G. Encoding and decoding cellular information through signaling dynamics. Cell. 152: 945-56. PMID 23452846 DOI: 10.1016/J.Cell.2013.02.005  0.314
2012 Purvis JE, Karhohs KW, Mock C, Batchelor E, Loewer A, Lahav G. p53 dynamics control cell fate. Science (New York, N.Y.). 336: 1440-4. PMID 22700930 DOI: 10.1126/Science.1218351  0.376
2010 Chatterjee MS, Purvis JE, Brass LF, Diamond SL. Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuli. Nature Biotechnology. 28: 727-32. PMID 20562863 DOI: 10.1038/Nbt.1642  0.695
2010 Shah PP, Wang T, Kaletsky RL, Myers MC, Purvis JE, Jing H, Huryn DM, Greenbaum DC, Smith AB, Bates P, Diamond SL. A small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells. Molecular Pharmacology. 78: 319-24. PMID 20466822 DOI: 10.1124/Mol.110.064261  0.629
2010 Beavers MP, Myers MC, Shah PP, Purvis JE, Diamond SL, Cooperman BS, Huryn DM, Smith AB. Erratum: Molecular docking of cathepsin l inhibitors in the binding site of papain (Journal of Chemical Information and Modeling (2008) 48 (1464-1472)) Journal of Chemical Information and Modeling. 50. DOI: 10.1021/Ci100114E  0.481
2009 Purvis JE, Radhakrishnan R, Diamond SL. Steady-state kinetic modeling constrains cellular resting states and dynamic behavior. Plos Computational Biology. 5: e1000298. PMID 19266013 DOI: 10.1371/Journal.Pcbi.1000298  0.519
2008 Shih AJ, Purvis J, Radhakrishnan R. Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing. Molecular Biosystems. 4: 1151-9. PMID 19396377 DOI: 10.1039/B803806F  0.376
2008 Beavers MP, Myers MC, Shah PP, Purvis JE, Diamond SL, Cooperman BS, Huryn DM, Smith AB. Molecular docking of cathepsin L inhibitors in the binding site of papain. Journal of Chemical Information and Modeling. 48: 1464-72. PMID 18598021 DOI: 10.1021/Ci800085C  0.482
2008 Purvis JE, Chatterjee MS, Brass LF, Diamond SL. A molecular signaling model of platelet phosphoinositide and calcium regulation during homeostasis and P2Y1 activation. Blood. 112: 4069-79. PMID 18596227 DOI: 10.1182/Blood-2008-05-157883  0.711
2008 Purvis J, Ilango V, Radhakrishnan R. Role of network branching in eliciting differential short-term signaling responses in the hypersensitive epidermal growth factor receptor mutants implicated in lung cancer. Biotechnology Progress. 24: 540-53. PMID 18412405 DOI: 10.1021/Bp070405O  0.344
2008 Shah PP, Myers MC, Beavers MP, Purvis JE, Jing H, Grieser HJ, Sharlow ER, Napper AD, Huryn DM, Cooperman BS, Smith AB, Diamond SL. Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L. Molecular Pharmacology. 74: 34-41. PMID 18403718 DOI: 10.1124/Mol.108.046219  0.506
2008 Purvis JE, Chatterjee MS, Brass LF, Diamond SL. Reverse engineering the human platelet Aiche Annual Meeting, Conference Proceedings.  0.667
2007 Liu Y, Purvis J, Shih A, Weinstein J, Agrawal N, Radhakrishnan R. A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations. Annals of Biomedical Engineering. 35: 1012-25. PMID 17273938 DOI: 10.1007/S10439-006-9251-0  0.346
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