| Year |
Citation |
Score |
| 2020 |
Yan HHN, Siu HC, Ho SL, Yue SSK, Gao Y, Tsui WY, Chan D, Chan AS, Wong JWH, Man AHY, Lee BCH, Chan ASY, Chan AKW, Hui HS, Cheung AKL, ... ... Leung SY, et al. Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles. Gut. PMID 32217638 DOI: 10.1136/Gutjnl-2019-320019 |
0.354 |
|
| 2019 |
Wallaschek N, Niklas C, Pompaiah M, Wiegering A, Germer CT, Kircher S, Brändlein S, Maurus K, Rosenwald A, Yan HHN, Leung SY, Bartfeld S. Establishing Pure Cancer Organoid Cultures: Identification, Selection and Verification of Cancer Phenotypes and Genotypes. Journal of Molecular Biology. PMID 31150736 DOI: 10.1016/J.Jmb.2019.05.031 |
0.334 |
|
| 2019 |
Weigel C, Chaisaingmongkol J, Assenov Y, Kuhmann C, Winkler V, Santi I, Bogatyrova O, Kaucher S, Bermejo JL, Leung SY, Chan TL, Lasitschka F, Bohrer MH, Marx A, Haußen RH, et al. DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer. Clinical Epigenetics. 11: 67. PMID 31053176 DOI: 10.1186/S13148-019-0666-5 |
0.328 |
|
| 2018 |
Yan HHN, Siu HC, Law S, Ho SL, Yue SSK, Tsui WY, Chan D, Chan AS, Ma S, Lam KO, Bartfeld S, Man AHY, Lee BCH, Chan ASY, Wong JWH, ... ... Leung SY, et al. A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening. Cell Stem Cell. PMID 30344100 DOI: 10.1016/J.Stem.2018.09.016 |
0.368 |
|
| 2017 |
Chan LH, Zhou L, Ng KY, Wong TL, Chai S, Lee TK, Guan XY, Ching YP, Lo CM, Man K, Artegiani B, Clevers H, Yan HH, Leung SY, Richard S, et al. Abstract LB-139: PRMT6-dependent CRAF/ERK signaling regulates cancer stem cell plasticity in liver cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-139 |
0.313 |
|
| 2017 |
Yue SSK, Yan HHN, Siu HC, Ho SL, Tsui WY, Chan D, Chan ASY, Lee BCH, Chan AKW, Leung SY. Abstract 4378: Gastric cancer organoid culture shows preserved genomic stability in long-term passage Cancer Research. 77: 4378-4378. DOI: 10.1158/1538-7445.Am2017-4378 |
0.341 |
|
| 2017 |
Yan HHN, Lai JCW, Ho SL, Chan AKW, Tsui WY, Chan ASY, Yuen ST, Leung SY. Abstract 1448: Unraveling the oncogenic pathway of serrated polyposis syndrome driven by RNF43 germline mutation Cancer Research. 77: 1448-1448. DOI: 10.1158/1538-7445.Am2017-1448 |
0.336 |
|
| 2016 |
Yuen ST, Leung SY. Genomics Study of Gastric Cancer and Its Molecular Subtypes. Advances in Experimental Medicine and Biology. 908: 419-39. PMID 27573784 DOI: 10.1007/978-3-319-41388-4_21 |
0.333 |
|
| 2016 |
Yan HH, Lai JC, Ho SL, Leung WK, Law WL, Lee JF, Chan AK, Tsui WY, Chan AS, Lee BC, Yue SS, Man AH, Clevers H, Yuen ST, Leung SY. RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation. Gut. PMID 27329244 DOI: 10.1136/Gutjnl-2016-311849 |
0.342 |
|
| 2016 |
Yoo S, Leung SY, Zhu J. Abstract B22: Integrative analysis of DNA methylation and gene expression data reveals complex regulation of gastric cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B22 |
0.358 |
|
| 2016 |
Wang K, Siu H, Deng S, Bienkowska JR, Leung SY. Abstract 4143: Characterizing the immunogenicity of gastric cancer by transcriptomic expression based immune phenotyping Cancer Research. 76: 4143-4143. DOI: 10.1158/1538-7445.Am2016-4143 |
0.34 |
|
| 2015 |
Alexandrov LB, Nik-Zainal S, Siu HC, Leung SY, Stratton MR. A mutational signature in gastric cancer suggests therapeutic strategies. Nature Communications. 6: 8683. PMID 26511885 DOI: 10.1038/Ncomms9683 |
0.358 |
|
| 2015 |
Leung WK, Tong DKH, Leung SY, Chan FSY, Tong TSM, Ho RSL, Chu KM, Law SYK. Treatment of Gastric Metaplasia or Dysplasia by Endoscopic Radiofrequency Ablation: A Pilot Study. Hepato-Gastroenterology. 62: 748-751. DOI: 10.5754/Hge14816 |
0.308 |
|
| 2015 |
Wang K, Leung SY. Abstract PR06: Genomic characterization of immune escape pathways in gastric cancer Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-Pr06 |
0.352 |
|
| 2014 |
Wang K, Yuen ST, Xu J, Lee SP, Yan HH, Shi ST, Siu HC, Deng S, Chu KM, Law S, Chan KH, Chan AS, Tsui WY, Ho SL, Chan AK, ... ... Leung SY, et al. Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. Nature Genetics. 46: 573-82. PMID 24816253 DOI: 10.1038/Ng.2983 |
0.374 |
|
| 2014 |
Kuhmann C, Li C, Kloor M, Salou M, Weigel C, Schmidt CR, Ng LW, Tsui WW, Leung SY, Yuen ST, Becker N, Weichenhan D, Plass C, Schmezer P, Chan TL, et al. Altered regulation of DNA ligase IV activity by aberrant promoter DNA methylation and gene amplification in colorectal cancer. Human Molecular Genetics. 23: 2043-54. PMID 24282031 DOI: 10.1093/Hmg/Ddt599 |
0.34 |
|
| 2012 |
Fan B, Dachrut S, Coral H, Yuen ST, Chu KM, Law S, Zhang L, Ji J, Leung SY, Chen X. Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer. Plos One. 7: e29824. PMID 22539939 DOI: 10.1371/Journal.Pone.0029824 |
0.323 |
|
| 2012 |
Chan T, Li C, Yuen S, Chan AK, Tsui WW, Chan AS, Leung S. Abstract LB-380: Distinct methylation pattern in early-onset colorectal cancer patients without detectable germline mutation Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-380 |
0.372 |
|
| 2012 |
Li G, Fan C, Deng S, Xu J, Shi S, Wang K, Pascual B, Kung P, Leung SY, Yue ST. Abstract 4535: CENP-E and c-Myc expression identifies a sensitive population of gastric cancer Cancer Research. 72: 4535-4535. DOI: 10.1158/1538-7445.Am2012-4535 |
0.346 |
|
| 2012 |
Popanda O, Kuhmann C, Schmezer P, Li C, Wing L, Leung S, Kloor M, Weichenhan D, Plass C, Chan T. 529 Promoter Methylation of the Ligase IV Gene in Human Colorectal Cancer European Journal of Cancer. 48: S125-S126. DOI: 10.1016/S0959-8049(12)71189-9 |
0.324 |
|
| 2011 |
Wang K, Kan J, Yuen ST, Shi ST, Chu KM, Law S, Chan TL, Kan Z, Chan AS, Tsui WY, Lee SP, Ho SL, Chan AK, Cheng GH, Roberts PC, ... ... Leung SY, et al. Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer. Nature Genetics. 43: 1219-23. PMID 22037554 DOI: 10.1038/Ng.982 |
0.383 |
|
| 2011 |
Kempers MJ, Kuiper RP, Ockeloen CW, Chappuis PO, Hutter P, Rahner N, Schackert HK, Steinke V, Holinski-Feder E, Morak M, Kloor M, Büttner R, Verwiel ET, van Krieken JH, Nagtegaal ID, ... ... Leung SY, et al. Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study. The Lancet. Oncology. 12: 49-55. PMID 21145788 DOI: 10.1016/S1470-2045(10)70265-5 |
0.346 |
|
| 2010 |
Poulogiannis G, Ichimura K, Hamoudi RA, Luo F, Leung SY, Yuen ST, Harrison DJ, Wyllie AH, Arends MJ. Prognostic relevance of DNA copy number changes in colorectal cancer. The Journal of Pathology. 220: 338-47. PMID 19911421 DOI: 10.1002/Path.2640 |
0.313 |
|
| 2010 |
Yan HHN, Li VSW, Chan TL, Yuen ST, Yeung BHY, Chan ASY, Tsui WY, Law WL, Au GKH, Kwong DLW, Leung SY. Abstract 5016: Retinoic acid receptor responder 3 expression suppresses colorectal cancer cell growthin vitroand is a stage-independent prognostic marker in colorectal cancer patientsin vivo Cancer Research. 70: 5016-5016. DOI: 10.1158/1538-7445.Am10-5016 |
0.375 |
|
| 2010 |
Li C, Yuen ST, Anthony, Chan KW, Tsui WWY, Chan ASY, Leung SY, Chan TL. Abstract 4909: The role of CpG island methylator phenotype 2 (CIMP2) in early onset colorectal cancer patients Cancer Research. 70: 4909-4909. DOI: 10.1158/1538-7445.Am10-4909 |
0.356 |
|
| 2009 |
Schetter AJ, Nguyen GH, Bowman ED, Mathé EA, Yuen ST, Hawkes JE, Croce CM, Leung SY, Harris CC. Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5878-87. PMID 19737943 DOI: 10.1158/1078-0432.Ccr-09-0627 |
0.329 |
|
| 2009 |
Xia HH, Yang Y, Chu KM, Gu Q, Zhang YY, He H, Wong WM, Leung SY, Yuen ST, Yuen MF, Chan AO, Wong BC. Serum macrophage migration-inhibitory factor as a diagnostic and prognostic biomarker for gastric cancer. Cancer. 115: 5441-9. PMID 19685530 DOI: 10.1002/Cncr.24609 |
0.325 |
|
| 2009 |
van Haaften G, Dalgliesh GL, Davies H, Chen L, Bignell G, Greenman C, Edkins S, Hardy C, O'Meara S, Teague J, Butler A, Hinton J, Latimer C, Andrews J, Barthorpe S, ... ... Leung SY, et al. Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer. Nature Genetics. 41: 521-3. PMID 19330029 DOI: 10.1038/Ng.349 |
0.332 |
|
| 2009 |
Li VS, Yuen ST, Chan TL, Yan HH, Law WL, Yeung BH, Chan AS, Tsui WY, So S, Chen X, Leung SY. Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms. Gastroenterology. 137: 176-87. PMID 19303019 DOI: 10.1053/J.Gastro.2009.03.005 |
0.349 |
|
| 2009 |
Ligtenberg MJ, Kuiper RP, Chan TL, Goossens M, Hebeda KM, Voorendt M, Lee TY, Bodmer D, Hoenselaar E, Hendriks-Cornelissen SJ, Tsui WY, Kong CK, Brunner HG, van Kessel AG, Yuen ST, ... ... Leung SY, et al. Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1. Nature Genetics. 41: 112-7. PMID 19098912 DOI: 10.1038/Ng.283 |
0.339 |
|
| 2008 |
Suehiro Y, Wong CW, Chirieac LR, Kondo Y, Shen L, Webb CR, Chan YW, Chan AS, Chan TL, Wu TT, Rashid A, Hamanaka Y, Hinoda Y, Shannon RL, Wang X, ... ... Leung SY, et al. Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 2560-9. PMID 18451217 DOI: 10.1158/1078-0432.Ccr-07-1802 |
0.321 |
|
| 2008 |
Schetter AJ, Leung SY, Sohn JJ, Zanetti KA, Bowman ED, Yanaihara N, Yuen ST, Chan TL, Kwong DL, Au GK, Liu CG, Calin GA, Croce CM, Harris CC. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. Jama. 299: 425-36. PMID 18230780 DOI: 10.1001/Jama.299.4.425 |
0.315 |
|
| 2007 |
Sääf AM, Halbleib JM, Chen X, Yuen ST, Leung SY, Nelson WJ, Brown PO. Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer. Molecular Biology of the Cell. 18: 4245-60. PMID 17699589 DOI: 10.1091/Mbc.E07-04-0309 |
0.309 |
|
| 2007 |
Chan AO, Chu KM, Huang C, Lam KF, Leung SY, Sun YW, Ko S, Xia HH, Cho CH, Hui WM, Lam SK, Rashid A. Association between Helicobacter pylori infection and interleukin 1beta polymorphism predispose to CpG island methylation in gastric cancer. Gut. 56: 595-7. PMID 17369391 DOI: 10.1136/Gut.2006.113258 |
0.332 |
|
| 2007 |
Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, ... ... Leung SY, et al. Patterns of somatic mutation in human cancer genomes. Nature. 446: 153-8. PMID 17344846 DOI: 10.1038/Nature05610 |
0.356 |
|
| 2006 |
Zou B, Chim CS, Zeng H, Leung SY, Yang Y, Tu SP, Lin MC, Wang J, He H, Jiang SH, Sun YW, Yu LF, Yuen ST, Kung HF, Wong BC. Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. Gastroenterology. 131: 1835-43. PMID 17087954 DOI: 10.1053/J.Gastro.2006.09.050 |
0.365 |
|
| 2006 |
Sheng JQ, Chan TL, Chan YW, Huang JS, Chen JG, Zhang MZ, Guo XL, Mu H, Chan AS, Li SR, Yuen ST, Leung SY. Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer. Chinese Journal of Digestive Diseases. 7: 197-205. PMID 17054581 DOI: 10.1111/J.1443-9573.2006.00269.X |
0.33 |
|
| 2006 |
Edkins S, O'Meara S, Parker A, Stevens C, Reis M, Jones S, Greenman C, Davies H, Dalgliesh G, Forbes S, Hunter C, Smith R, Stephens P, Goldstraw P, Nicholson A, ... ... Leung SY, et al. Recurrent KRAS codon 146 mutations in human colorectal cancer. Cancer Biology & Therapy. 5: 928-32. PMID 16969076 DOI: 10.4161/Cbt.5.8.3251 |
0.333 |
|
| 2006 |
Chan TL, Yuen ST, Kong CK, Chan YW, Chan AS, Ng WF, Tsui WY, Lo MW, Tam WY, Li VS, Leung SY. Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer. Nature Genetics. 38: 1178-83. PMID 16951683 DOI: 10.1038/Ng1866 |
0.357 |
|
| 2006 |
Leung SY, Ho C, Tu IP, Li R, So S, Chu KM, Yuen ST, Chen X. Comprehensive analysis of 19q12 amplicon in human gastric cancers. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 854-63. PMID 16575401 DOI: 10.1038/Modpathol.3800593 |
0.307 |
|
| 2006 |
Iacopetta B, Russo A, Bazan V, Dardanoni G, Gebbia N, Soussi T, Kerr D, Elsaleh H, Soong R, Kandioler D, Janschek E, Kappel S, Lung M, Leung CS, Ko JM, ... ... Leung SY, et al. Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 17: 842-7. PMID 16524972 DOI: 10.1093/Annonc/Mdl035 |
0.334 |
|
| 2006 |
Aggarwal A, Guo DL, Hoshida Y, Yuen ST, Chu KM, So S, Boussioutas A, Chen X, Bowtell D, Aburatani H, Leung SY, Tan P. Topological and functional discovery in a gene coexpression meta-network of gastric cancer. Cancer Research. 66: 232-41. PMID 16397236 DOI: 10.1158/0008-5472.Can-05-2232 |
0.365 |
|
| 2006 |
Guo DL, Zhang J, Yuen ST, Tsui WY, Chan AS, Ho C, Ji J, Leung SY, Chen X. Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours. Carcinogenesis. 27: 454-64. PMID 16272170 DOI: 10.1093/Carcin/Bgi259 |
0.34 |
|
| 2005 |
Giacomini CP, Leung SY, Chen X, Yuen ST, Kim YH, Bair E, Pollack JR. A gene expression signature of genetic instability in colon cancer. Cancer Research. 65: 9200-5. PMID 16230380 DOI: 10.1158/0008-5472.Can-04-4163 |
0.373 |
|
| 2005 |
Davies H, Hunter C, Smith R, Stephens P, Greenman C, Bignell G, Teague J, Butler A, Edkins S, Stevens C, Parker A, O'Meara S, Avis T, Barthorpe S, Brackenbury L, ... ... Leung SY, et al. Somatic mutations of the protein kinase gene family in human lung cancer. Cancer Research. 65: 7591-5. PMID 16140923 DOI: 10.1158/0008-5472.Can-05-1855 |
0.323 |
|
| 2005 |
Stephens P, Edkins S, Davies H, Greenman C, Cox C, Hunter C, Bignell G, Teague J, Smith R, Stevens C, O'Meara S, Parker A, Tarpey P, Avis T, Barthorpe A, ... ... Leung SY, et al. A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. Nature Genetics. 37: 590-2. PMID 15908952 DOI: 10.1038/Ng1571 |
0.313 |
|
| 2005 |
Li VS, Wong CW, Chan TL, Chan AS, Zhao W, Chu KM, So S, Chen X, Yuen ST, Leung SY. Mutations of PIK3CA in gastric adenocarcinoma. Bmc Cancer. 5: 29. PMID 15784156 DOI: 10.1186/1471-2407-5-29 |
0.362 |
|
| 2005 |
Ko S, Chu KM, Luk JM, Wong BW, Yuen ST, Leung SY, Wong J. CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of the stomach. The Journal of Pathology. 205: 615-22. PMID 15732140 DOI: 10.1002/Path.1741 |
0.369 |
|
| 2004 |
Stephens P, Hunter C, Bignell G, Edkins S, Davies H, Teague J, Stevens C, O'Meara S, Smith R, Parker A, Barthorpe A, Blow M, Brackenbury L, Butler A, Clarke O, ... ... Leung SY, et al. Lung cancer: intragenic ERBB2 kinase mutations in tumours. Nature. 431: 525-6. PMID 15457249 DOI: 10.1038/431525B |
0.314 |
|
| 2004 |
He QY, Cheung YH, Leung SY, Yuen ST, Chu KM, Chiu JF. Diverse proteomic alterations in gastric adenocarcinoma. Proteomics. 4: 3276-87. PMID 15378696 DOI: 10.1002/Pmic.200300916 |
0.356 |
|
| 2004 |
Subramanian S, West RB, Corless CL, Ou W, Rubin BP, Chu KM, Leung SY, Yuen ST, Zhu S, Hernandez-Boussard T, Montgomery K, Nielsen TO, Patel RM, Goldblum JR, Heinrich MC, et al. Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles. Oncogene. 23: 7780-90. PMID 15326474 DOI: 10.1038/Sj.Onc.1208056 |
0.33 |
|
| 2004 |
Leung SY, Yuen ST, Chu KM, Mathy JA, Li R, Chan AS, Law S, Wong J, Chen X, So S. Expression profiling identifies chemokine (C-C motif) ligand 18 as an independent prognostic indicator in gastric cancer. Gastroenterology. 127: 457-69. PMID 15300578 DOI: 10.1053/J.Gastro.2004.05.031 |
0.367 |
|
| 2004 |
Xia HH, Yang Y, Lam SK, Wong WM, Leung SY, Yuen ST, Elia G, Wright NA, Wong BC. Aberrant epithelial expression of trefoil family factor 2 and mucin 6 in Helicobacter pylori infected gastric antrum, incisura, and body and its association with antralisation. Journal of Clinical Pathology. 57: 861-6. PMID 15280409 DOI: 10.1136/Jcp.2003.015487 |
0.303 |
|
| 2004 |
Ko S, Chu KM, Luk JM, Wong BW, Yuen ST, Leung SY, Wong J. Overexpression of LI-cadherin in gastric cancer is associated with lymph node metastasis. Biochemical and Biophysical Research Communications. 319: 562-8. PMID 15178443 DOI: 10.1016/J.Bbrc.2004.04.197 |
0.351 |
|
| 2004 |
Chan TL, Chan YW, Ho JW, Chan C, Chan AS, Chan E, Lam PW, Tse CW, Lee KC, Lau CW, Gwi E, Leung SY, Yuen ST. MSH2 c.1452-1455delAATG is a founder mutation and an important cause of hereditary nonpolyposis colorectal cancer in the southern Chinese population. American Journal of Human Genetics. 74: 1035-42. PMID 15042510 DOI: 10.1086/383591 |
0.339 |
|
| 2004 |
Wong BC, Lam SK, Wong WM, Chen JS, Zheng TT, Feng RE, Lai KC, Hu WH, Yuen ST, Leung SY, Fong DY, Ho J, Ching CK, Chen JS. Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial. Jama. 291: 187-94. PMID 14722144 DOI: 10.1001/Jama.291.2.187 |
0.318 |
|
| 2004 |
Zhao W, Chan TL, Chu KM, Chan AS, Stratton MR, Yuen ST, Leung SY. Mutations of BRAF and KRAS in gastric cancer and their association with microsatellite instability. International Journal of Cancer. Journal International Du Cancer. 108: 167-9. PMID 14618633 DOI: 10.1002/Ijc.11553 |
0.337 |
|
| 2003 |
Chan AS, Tsui WY, Chen X, Chu KM, Chan TL, Chan AS, Li R, So S, Yuen ST, Leung SY. Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma. Oncogene. 22: 6946-53. PMID 14534543 DOI: 10.1038/Sj.Onc.1206799 |
0.366 |
|
| 2003 |
Chen X, Leung SY, Yuen ST, Chu KM, Ji J, Li R, Chan AS, Law S, Troyanskaya OG, Wong J, So S, Botstein D, Brown PO. Variation in gene expression patterns in human gastric cancers. Molecular Biology of the Cell. 14: 3208-15. PMID 12925757 DOI: 10.1091/Mbc.E02-12-0833 |
0.37 |
|
| 2002 |
Leung SY, Chen X, Chu KM, Yuen ST, Mathy J, Ji J, Chan AS, Li R, Law S, Troyanskaya OG, Tu IP, Wong J, So S, Botstein D, Brown PO. Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis. Proceedings of the National Academy of Sciences of the United States of America. 99: 16203-8. PMID 12456890 DOI: 10.1073/Pnas.212646299 |
0.373 |
|
| 2002 |
Yuen ST, Chan TL, Ho JW, Chan AS, Chung LP, Lam PW, Tse CW, Wyllie AH, Leung SY. Germline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers. Oncogene. 21: 7585-92. PMID 12386821 DOI: 10.1038/Sj.Onc.1205968 |
0.357 |
|
| 2002 |
Ji J, Chen X, Leung SY, Chi JT, Chu KM, Yuen ST, Li R, Chan AS, Li J, Dunphy N, So S. Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines. Oncogene. 21: 6549-56. PMID 12226758 DOI: 10.1038/Sj.Onc.1205829 |
0.358 |
|
| 2002 |
Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, ... ... Leung SY, et al. Mutations of the BRAF gene in human cancer. Nature. 417: 949-54. PMID 12068308 DOI: 10.1038/Nature00766 |
0.339 |
|
| 2001 |
Chan TL, Curtis LC, Leung SY, Farrington SM, Ho JW, Chan AS, Lam PW, Tse CW, Dunlop MG, Wyllie AH, Yuen ST. Early-onset colorectal cancer with stable microsatellite DNA and near-diploid chromosomes. Oncogene. 20: 4871-6. PMID 11521198 DOI: 10.1038/Sj.Onc.1204653 |
0.34 |
|
| 2001 |
Chan TL, Yuen ST, Ho JW, Chan AS, Kwan K, Chung LP, Lam PW, Tse CW, Leung SY. A novel germline 1.8-kb deletion of hMLH1 mimicking alternative splicing: a founder mutation in the Chinese population. Oncogene. 20: 2976-81. PMID 11420710 DOI: 10.1038/Sj.Onc.1204376 |
0.329 |
|
| 2001 |
Chan AO, Chu KM, Yuen ST, Leung SY, Lam SK, Wong J. Synchronous gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma in association with Helicobacter pylori infection: comparing reported cases between the East and West. The American Journal of Gastroenterology. 96: 1922-4. PMID 11419851 DOI: 10.1111/J.1572-0241.2001.03895.X |
0.316 |
|
| 2001 |
Chan AO, Lam SK, Chu KM, Lam CM, Kwok E, Leung SY, Yuen ST, Law SY, Hui WM, Lai KC, Wong CY, Hu HC, Lai CL, Wong J. Soluble E-cadherin is a valid prognostic marker in gastric carcinoma. Gut. 48: 808-11. PMID 11358900 DOI: 10.1136/Gut.48.6.808 |
0.343 |
|
| 2000 |
Leung SY, Yuen ST, Chan TL, Chan AS, Ho JW, Kwan K, Fan YW, Hung KN, Chung LP, Wyllie AH. Chromosomal instability and p53 inactivation are required for genesis of glioblastoma but not for colorectal cancer in patients with germline mismatch repair gene mutation. Oncogene. 19: 4079-83. PMID 10962567 DOI: 10.1038/Sj.Onc.1203740 |
0.333 |
|
| 2000 |
Ho JW, Yuen ST, Chung LP, Kwan KY, Chan TL, Leung SY, Chan AS, Tse Cw, Lam PW, Luk IS. Distinct clinical features associated with microsatellite instability in colorectal cancers of young patients. International Journal of Cancer. Journal International Du Cancer. 89: 356-60. PMID 10956410 DOI: 10.1002/1097-0215(20000720)89:4<356::Aid-Ijc7>3.0.Co;2-J |
0.367 |
|
| 1999 |
Chan TL, Yuen ST, Chung LP, Ho JW, Kwan KY, Chan AS, Ho JC, Leung SY, Wyllie AH. Frequent microsatellite instability and mismatch repair gene mutations in young Chinese patients with colorectal cancer. Journal of the National Cancer Institute. 91: 1221-6. PMID 10413423 DOI: 10.1093/Jnci/91.14.1221 |
0.366 |
|
| 1999 |
Wong MP, Cheung N, Yuen ST, Leung SY, Chung LP. Vascular endothelial growth factor is up-regulated in the early pre-malignant stage of colorectal tumour progression. International Journal of Cancer. Journal International Du Cancer. 81: 845-50. PMID 10362127 DOI: 10.1002/(Sici)1097-0215(19990611)81:6<845::Aid-Ijc1>3.0.Co;2-5 |
0.303 |
|
| 1999 |
Chan TL, Yuen ST, Chung LP, Ho JW, Kwan K, Fan YW, Chan AS, Leung SY. Germline hMSH2 and differential somatic mutations in patients with Turcot's syndrome. Genes, Chromosomes & Cancer. 25: 75-81. PMID 10337989 DOI: 10.1002/(Sici)1098-2264(199906)25:2<75::Aid-Gcc1>3.0.Co;2-1 |
0.332 |
|
| 1999 |
Leung SY, Yuen ST, Chung LP, Chu KM, Wong MP, Branicki FJ, Ho JC. Microsatellite instability, Epstein-Barr virus, mutation of type II transforming growth factor beta receptor and BAX in gastric carcinomas in Hong Kong Chinese. British Journal of Cancer. 79: 582-8. PMID 10027334 DOI: 10.1038/Sj.Bjc.6690092 |
0.332 |
|
| 1998 |
Wong MP, Cheung KN, Yuen ST, Fu KH, Chan AS, Leung SY, Chung LP. Monocyte chemoattractant protein-1 (MCP-1) expression in primary lymphoepithelioma-like carcinomas (LELCs) of the lung. The Journal of Pathology. 186: 372-7. PMID 10209485 DOI: 10.1002/(Sici)1096-9896(199812)186:4<372::Aid-Path204>3.0.Co;2-8 |
0.303 |
|
| 1998 |
Leung SY, Chan TL, Chung LP, Chan AS, Fan YW, Hung KN, Kwong WK, Ho JW, Yuen ST. Microsatellite instability and mutation of DNA mismatch repair genes in gliomas. The American Journal of Pathology. 153: 1181-8. PMID 9777949 DOI: 10.1016/S0002-9440(10)65662-3 |
0.375 |
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| 1998 |
Yuen ST, Wong MP, Chung LP, Chan SY, Cheung N, Ho J, Leung SY. Up-regulation of lysozyme production in colonic adenomas and adenocarcinomas. Histopathology. 32: 126-32. PMID 9543668 DOI: 10.1046/J.1365-2559.1998.00339.X |
0.343 |
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| 1997 |
Yuen ST, Chung LP, Leung SY, Luk IS, Chan SY, Ho JC, Ho JW, Wyllie AH. Colorectal carcinoma in Hong Kong: epidemiology and genetic mutations. British Journal of Cancer. 76: 1610-6. PMID 9413950 DOI: 10.1038/Bjc.1997.605 |
0.328 |
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| 1997 |
Leung SY, Yuen ST, Chung LP, Chan AS, Wong MP. Prevalence of mutations and 30-bp deletion in the C-terminal region of Epstein-Barr virus latent membrane protein-1 oncogene in reactive lymphoid tissue and non-nasopharyngeal EBV-associated carcinomas in Hong Kong Chinese. International Journal of Cancer. Journal International Du Cancer. 72: 225-30. PMID 9219824 DOI: 10.1002/(Sici)1097-0215(19970717)72:2<225::Aid-Ijc4>3.0.Co;2-T |
0.316 |
|
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