| Year |
Citation |
Score |
| 2019 |
Toubai T, Fujiwara H, Rossi C, Riwes M, Tamaki H, Zajac C, Liu C, Mathew AV, Byun J, Oravecz-Wilson K, Matsuda I, Sun Y, Peltier D, Wu J, Chen J, ... Seregin S, et al. Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition. Nature Microbiology. PMID 30858572 DOI: 10.1038/S41564-019-0373-1 |
0.364 |
|
| 2018 |
Kady NM, Liu X, Lydic TA, Syed MH, Navitskaya S, Wang Q, Hammer SS, O'Reilly S, Huang C, Seregin SS, Amalfitano A, Chiodo VA, Boye SL, Hauswirth WW, Antonetti DA, et al. ELOVL4-Mediated Production of Very Long Chain Ceramides Stabilizes Tight Junctions and Prevents Diabetes-Induced Retinal Vascular Permeability. Diabetes. PMID 29362226 DOI: 10.2337/Db17-1034 |
0.5 |
|
| 2016 |
Rastall DP, Seregin SS, Aldhamen YA, Kaiser LM, Mullins C, Liou A, Ing F, Pereria-Hicks C, Godbehere-Roosa S, Palmer D, Ng P, Amalfitano A. Long-term, high level hepatic secretion of acid α-glucosidase for Pompe disease achieved in non-human primates using helper-dependent adenovirus. Gene Therapy. PMID 27367841 DOI: 10.1038/Gt.2016.53 |
0.74 |
|
| 2016 |
Aldhamen YA, Rastall DP, Chen W, Seregin SS, Pereira-Hicks C, Godbehere S, Kaminski NE, Amalfitano A. CRACC-targeting Fc-fusion protein induces activation of NK cells and DCs and improves T cell immune responses to antigenic targets. Vaccine. PMID 27151882 DOI: 10.1016/J.Vaccine.2016.04.068 |
0.834 |
|
| 2016 |
Alyaqoub FS, Aldhamen YA, Koestler BJ, Bruger EL, Seregin SS, Pereira-Hicks C, Godbehere S, Waters CM, Amalfitano A. In Vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses against Extracellular Antigens. Journal of Immunology (Baltimore, Md. : 1950). PMID 26792800 DOI: 10.4049/Jimmunol.1501272 |
0.845 |
|
| 2015 |
Aldhamen YA, Pepelyayeva Y, Rastall DP, Seregin SS, Zervoudi E, Koumantou D, Aylsworth CF, Quiroga D, Godbehere S, Georgiadis D, Stratikos E, Amalfitano A. Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells. Journal of Innate Immunity. 7: 275-89. PMID 25591727 DOI: 10.1159/000368899 |
0.83 |
|
| 2014 |
Koestler BJ, Seregin SS, Rastall DP, Aldhamen YA, Godbehere S, Amalfitano A, Waters CM. Stimulation of innate immunity by in vivo cyclic di-GMP synthesis using adenovirus. Clinical and Vaccine Immunology : Cvi. 21: 1550-9. PMID 25230938 DOI: 10.1128/Cvi.00471-14 |
0.826 |
|
| 2014 |
Rastall DP, Aldhamen YA, Seregin SS, Godbehere S, Amalfitano A. ERAP1 functions override the intrinsic selection of specific antigens as immunodominant peptides, thereby altering the potency of antigen-specific cytolytic and effector memory T-cell responses. International Immunology. 26: 685-95. PMID 25087231 DOI: 10.1093/Intimm/Dxu078 |
0.766 |
|
| 2014 |
Aldhamen YA, Seregin SS, Aylsworth CF, Godbehere S, Amalfitano A. Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategy. International Immunology. 26: 291-303. PMID 24374770 DOI: 10.1093/Intimm/Dxt061 |
0.836 |
|
| 2013 |
Zervoudi E, Saridakis E, Birtley JR, Seregin SS, Reeves E, Kokkala P, Aldhamen YA, Amalfitano A, Mavridis IM, James E, Georgiadis D, Stratikos E. Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses. Proceedings of the National Academy of Sciences of the United States of America. 110: 19890-5. PMID 24248368 DOI: 10.1073/Pnas.1309781110 |
0.807 |
|
| 2013 |
Kovalenko PL, Yuan L, Sun K, Kunovska L, Seregin S, Amalfitano A, Basson MD. Regulation of epithelial differentiation in rat intestine by intraluminal delivery of an adenoviral vector or silencing RNA coding for Schlafen 3. Plos One. 8: e79745. PMID 24244554 DOI: 10.1371/Journal.Pone.0079745 |
0.614 |
|
| 2013 |
Seregin SS, Rastall DP, Evnouchidou I, Aylsworth CF, Quiroga D, Kamal RP, Godbehere-Roosa S, Blum CF, York IA, Stratikos E, Amalfitano A. Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens. Autoimmunity. 46: 497-508. PMID 24028501 DOI: 10.3109/08916934.2013.819855 |
0.771 |
|
| 2013 |
Aldhamen YA, Seregin SS, Kousa YA, Rastall DP, Appledorn DM, Godbehere S, Schutte BC, Amalfitano A. Improved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2. Cancer Gene Therapy. 20: 564-75. PMID 23949283 DOI: 10.1038/Cgt.2013.53 |
0.824 |
|
| 2013 |
Aldhamen YA, Seregin SS, Rastall DP, Aylsworth CF, Pepelyayeva Y, Busuito CJ, Godbehere-Roosa S, Kim S, Amalfitano A. Endoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune response. Plos One. 8: e69539. PMID 23894499 DOI: 10.1371/Journal.Pone.0069539 |
0.803 |
|
| 2013 |
Aylsworth CF, Aldhamen YA, Seregin SS, Godbehere S, Amalfitano A. Activation of human natural killer cells by the novel innate immune modulator recombinant Eimeria antigen. Human Immunology. 74: 916-26. PMID 23639554 DOI: 10.1016/J.Humimm.2013.04.035 |
0.811 |
|
| 2012 |
Evnouchidou I, Birtley J, Seregin S, Papakyriakou A, Zervoudi E, Samiotaki M, Panayotou G, Giastas P, Petrakis O, Georgiadis D, Amalfitano A, Saridakis E, Mavridis IM, Stratikos E. A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing. Journal of Immunology (Baltimore, Md. : 1950). 189: 2383-92. PMID 22837489 DOI: 10.4049/Jimmunol.1200918 |
0.604 |
|
| 2012 |
Aldhamen YA, Seregin SS, Schuldt NJ, Rastall DP, Liu CJ, Godbehere S, Amalfitano A. Vaccines expressing the innate immune modulator EAT-2 elicit potent effector memory T lymphocyte responses despite pre-existing vaccine immunity. Journal of Immunology (Baltimore, Md. : 1950). 189: 1349-59. PMID 22745373 DOI: 10.4049/Jimmunol.1200736 |
0.837 |
|
| 2012 |
Schuldt NJ, Aldhamen YA, Godbehere-Roosa S, Seregin SS, Kousa YA, Amalfitano A. Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and adenovirus (Ad5) immune mice. Malaria Journal. 11: 209. PMID 22720732 DOI: 10.1186/1475-2875-11-209 |
0.815 |
|
| 2012 |
Seregin SS, Aldhamen YA, Rastall DP, Godbehere S, Amalfitano A. Adenovirus-based vaccination against Clostridium difficile toxin A allows for rapid humoral immunity and complete protection from toxin A lethal challenge in mice. Vaccine. 30: 1492-501. PMID 22200503 DOI: 10.1016/J.Vaccine.2011.12.064 |
0.805 |
|
| 2012 |
Yuan L, Kovalenko PL, Patel SS, Seregin S, Amalfitano A, Basson MD. Mo2030 Induction of Intestinal Epithelial Differentiation by Intraluminal Delivery of an Adenoviral Vector Coding for Schlafen 3 Gastroenterology. 142: S-724. DOI: 10.1016/S0016-5085(12)62809-1 |
0.554 |
|
| 2012 |
Georgiadis D, Zervoudi E, Petraki O, Seregin S, Amalfitano A, Stratikos E. Small pseudopeptidic inhibitors of aminopeptidases that trim antigenic peptides can influence antigen presentation Molecular Immunology. 51: 32. DOI: 10.1016/J.Molimm.2012.02.091 |
0.594 |
|
| 2012 |
Evnouchidou I, Seregin S, Birtley J, Saridakis E, Mavridis I, Amalfitano A, Stratikos E. A common polymorphism in ER aminopeptidase 2 acts as a specificity switch and can influence antigenic peptide processing Molecular Immunology. 51: 32. DOI: 10.1016/J.Molimm.2012.02.090 |
0.569 |
|
| 2011 |
Aldhamen YA, Seregin SS, Amalfitano A. Immune recognition of gene transfer vectors: focus on adenovirus as a paradigm. Frontiers in Immunology. 2: 40. PMID 22566830 DOI: 10.3389/Fimmu.2011.00040 |
0.816 |
|
| 2011 |
Schuldt NJ, Aldhamen YA, Appledorn DM, Seregin SS, Kousa Y, Godbehere S, Amalfitano A. Vaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responses. Plos One. 6: e24147. PMID 21912619 DOI: 10.1371/Journal.Pone.0024147 |
0.82 |
|
| 2011 |
Seregin SS, Amalfitano A. Gene therapy for lysosomal storage diseases: progress, challenges and future prospects. Current Pharmaceutical Design. 17: 2558-74. PMID 21774776 DOI: 10.2174/138161211797247578 |
0.565 |
|
| 2011 |
Seregin SS, Aldhamen YA, Appledorn DM, Aylsworth CF, Godbehere S, Liu CJ, Quiroga D, Amalfitano A. TRIF is a critical negative regulator of TLR agonist mediated activation of dendritic cells in vivo. Plos One. 6: e22064. PMID 21760953 DOI: 10.1371/Journal.Pone.0022064 |
0.838 |
|
| 2011 |
Seregin SS, Aldhamen YA, Appledorn DM, Zehnder J, Voss T, Godbehere S, Amalfitano A. Use of DAF-displaying adenovirus vectors reduces induction of transgene- and vector-specific adaptive immune responses in mice. Human Gene Therapy. 22: 1083-94. PMID 21388344 DOI: 10.1089/Hum.2010.218 |
0.826 |
|
| 2011 |
Evnouchidou I, Kamal RP, Seregin SS, Goto Y, Tsujimoto M, Hattori A, Voulgari PV, Drosos AA, Amalfitano A, York IA, Stratikos E. Cutting Edge: Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic properties of the enzyme. Journal of Immunology (Baltimore, Md. : 1950). 186: 1909-13. PMID 21242517 DOI: 10.4049/Jimmunol.1003337 |
0.535 |
|
| 2011 |
Aldhamen YA, Appledorn DM, Seregin SS, Liu CJ, Schuldt NJ, Godbehere S, Amalfitano A. Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens. Journal of Immunology (Baltimore, Md. : 1950). 186: 722-32. PMID 21149608 DOI: 10.4049/Jimmunol.1002105 |
0.839 |
|
| 2011 |
Appledorn DM, Aldhamen YA, Godbehere S, Seregin SS, Amalfitano A. Sublingual administration of an adenovirus serotype 5 (Ad5)-based vaccine confirms Toll-like receptor agonist activity in the oral cavity and elicits improved mucosal and systemic cell-mediated responses against HIV antigens despite preexisting Ad5 immunity. Clinical and Vaccine Immunology : Cvi. 18: 150-60. PMID 21084461 DOI: 10.1128/Cvi.00341-10 |
0.84 |
|
| 2010 |
Seregin SS, Amalfitano A. Improving adenovirus based gene transfer: strategies to accomplish immune evasion. Viruses. 2: 2013-36. PMID 21994718 DOI: 10.3390/V2092013 |
0.676 |
|
| 2010 |
Seregin SS, Aldhamen YA, Appledorn DM, Hartman ZC, Schuldt NJ, Scott J, Godbehere S, Jiang H, Frank MM, Amalfitano A. Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo. Blood. 116: 1669-77. PMID 20511542 DOI: 10.1182/Blood-2010-03-276949 |
0.819 |
|
| 2010 |
Seregin SS, Hartman ZC, Appledorn DM, Godbehere S, Jiang H, Frank MM, Amalfitano A. Novel adenovirus vectors 'capsid-displaying' a human complement inhibitor. Journal of Innate Immunity. 2: 353-9. PMID 20375551 DOI: 10.1159/000284368 |
0.611 |
|
| 2010 |
Appledorn DM, Aldhamen YA, Depas W, Seregin SS, Liu CJ, Schuldt N, Quach D, Quiroga D, Godbehere S, Zlatkin I, Kim S, McCormick JJ, Amalfitano A. A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target. Plos One. 5: e9579. PMID 20221448 DOI: 10.1371/Journal.Pone.0009579 |
0.815 |
|
| 2010 |
Bazhan SI, Karpenko LI, Ilyicheva TN, Belavin PA, Seregin SV, Danilyuk NK, Antonets DV, Ilyichev AA. Rational design based synthetic polyepitope DNA vaccine for eliciting HIV-specific CD8+ T cell responses Molecular Immunology. 47: 1507-1515. PMID 20189249 DOI: 10.1016/j.molimm.2010.01.020 |
0.363 |
|
| 2010 |
Seregin SS, Appledorn DM, Patial S, Bujold M, Nance W, Godbehere S, Parameswaran N, Amalfitano A. beta-Arrestins modulate Adenovirus-vector-induced innate immune responses: differential regulation by beta-arrestin-1 and beta-arrestin-2. Virus Research. 147: 123-34. PMID 19896992 DOI: 10.1016/J.Virusres.2009.10.023 |
0.632 |
|
| 2009 |
Seregin SS, Amalfitano A. Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors. Expert Opinion On Biological Therapy. 9: 1521-31. PMID 19780714 DOI: 10.1517/14712590903307388 |
0.728 |
|
| 2009 |
Seregin SS, Aldhamen YA, Appledorn DM, Schuldt NJ, McBride AJ, Bujold M, Godbehere SS, Amalfitano A. CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies. Gene Therapy. 16: 1245-59. PMID 19554032 DOI: 10.1038/Gt.2009.77 |
0.834 |
|
| 2009 |
Seregin SS, Appledorn DM, McBride AJ, Schuldt NJ, Aldhamen YA, Voss T, Wei J, Bujold M, Nance W, Godbehere S, Amalfitano A. Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 685-96. PMID 19174760 DOI: 10.1038/Mt.2008.297 |
0.823 |
|
| 2008 |
Appledorn DM, McBride A, Seregin S, Scott JM, Schuldt N, Kiang A, Godbehere S, Amalfitano A. Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors. Gene Therapy. 15: 1606-17. PMID 18615115 DOI: 10.1038/Gt.2008.114 |
0.832 |
|
| 2008 |
Appledorn DM, Seregin S, Amalfitano A. Adenovirus vectors for renal-targeted gene delivery. Contributions to Nephrology. 159: 47-62. PMID 18391584 DOI: 10.1159/000125581 |
0.633 |
|
| 2008 |
Appledorn DM, Kiang A, McBride A, Jiang H, Seregin S, Scott JM, Stringer R, Kousa Y, Hoban M, Frank MM, Amalfitano A. Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent. Gene Therapy. 15: 885-901. PMID 18288208 DOI: 10.1038/Gt.2008.18 |
0.75 |
|
| 2007 |
Karpenko LI, Ilyichev AA, Eroshkin AM, Lebedev LR, Uzhachenko RV, Nekrasova NA, Plyasunova OA, Belavin PA, Seregin SV, Danilyuk NK, Zaitsev BN, Danilenko ED, Masycheva VI, Bazhan SI. Combined virus-like particle-based polyepitope DNA/protein HIV-1 vaccine. Design, immunogenicity and toxicity studies Vaccine. 25: 4312-4323. PMID 17418918 DOI: 10.1016/j.vaccine.2007.02.058 |
0.381 |
|
| 2005 |
Ilyichev AA, Karpenko LI, Nekrasova NA, Lebedev LR, Ignatev GM, Agafonov AP, Belavin PA, Seregin SS, Danilyuk NK, Bazhan SI. DIfferent systems of delivery of HIV-1 DNA vaccine encoding the multiepitope CTL-immunogene Vestnik Rossiiskoi Akademii Meditsinskikh Nauk. 41-44. PMID 15715155 |
0.416 |
|
| 2004 |
Karpenko LI, Nekrasova NA, Ilyichev AA, Lebedev LR, Ignatyev GM, Agafonov AP, Zaitsev BN, Belavin PA, Seregin SV, Danilyuk NK, Babkina IN, Bazhan SI. Comparative analysis using a mouse model of the immunogenicity of artificial VLP and attenuated Salmonella strain carrying a DNA-vaccine encoding HIV-1 polyepitope CTL-immunogen Vaccine. 22: 1692-1699. PMID 15068852 DOI: 10.1016/j.vaccine.2003.09.050 |
0.408 |
|
| 2004 |
Bazhan SI, Belavin PA, Seregin SV, Danilyuk NK, Babkina IN, Karpenko LI, Nekrasova NA, Lebedev LR, Ignatyev GM, Agafonov AP, Poryvaeva VA, Aborneva IV, Ilyichev AA. Designing and engineering of DNA-vaccine construction encoding multiple CTL-epitopes of major HIV-1 antigens Vaccine. 22: 1672-1682. PMID 15068850 DOI: 10.1016/j.vaccine.2003.09.048 |
0.369 |
|
| 2004 |
Bazhan SI, Belavin PA, Seregin SV, Danilyuk NK, Babkina IN, Karpenko LI, Nekrasova NA, Lebedev LR, Agafonov AP, Ignat'ev GM, Il'ichev AA, Sandakhchiev LS. Designing of artificial immunogen, a candidate of DNA-vaccine encoding multiple CTL epitopes of HIV-1 Doklady Akademii Nauk. 395: 825-827. |
0.383 |
|
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