Glenn C. Telling - Publications

Affiliations: 
Microbiology University of Kentucky, Lexington, KY 
Area:
Microbiology Biology, Molecular Biology, Neuroscience Biology

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Thackray AM, McNulty EE, Nalls AV, Smith A, Comoy E, Telling G, Benestad SL, Andréoletti O, Mathiason CK, Bujdoso R. Lack of prion transmission barrier in human PrP transgenic Drosophila. The Journal of Biological Chemistry. 107617. PMID 39089583 DOI: 10.1016/j.jbc.2024.107617  0.425
2024 Eraña H, Sampedro-Torres-Quevedo C, Charco JM, Díaz-Domínguez CM, Peccati F, San-Juan-Ansoleaga M, Vidal E, Gonçalves-Anjo N, Pérez-Castro MA, González-Miranda E, Piñeiro P, Fernández-Veiga L, Galarza-Ahumada J, Fernández-Muñoz E, Perez de Nanclares G, ... Telling G, et al. A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions. Nature Communications. 15: 2112. PMID 38459071 DOI: 10.1038/s41467-024-46360-2  0.406
2023 Thackray AM, McNulty EE, Nalls AV, Cardova A, Tran L, Telling G, Benestad SL, Gilch S, Mathiason CK, Bujdoso R. Genetic modulation of CWD prion propagation in cervid PrP Drosophila. The Biochemical Journal. 480: 1485-1501. PMID 37747806 DOI: 10.1042/BCJ20230247  0.492
2023 Eraña H, Díaz-Domínguez CM, Charco JM, Vidal E, González-Miranda E, Pérez-Castro MA, Piñeiro P, López-Moreno R, Sampedro-Torres-Quevedo C, Fernández-Veiga L, Tasis-Galarza J, Lorenzo NL, Santini-Santiago A, Lázaro M, García-Martínez S, ... ... Telling GC, et al. Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation. Acta Neuropathologica Communications. 11: 145. PMID 37679832 DOI: 10.1186/s40478-023-01640-8  0.441
2023 Sun JL, Telling GC. New developments in prion disease research using genetically modified mouse models. Cell and Tissue Research. 392: 33-46. PMID 36929219 DOI: 10.1007/s00441-023-03761-x  0.423
2023 Sun JL, Kim S, Crowell J, Webster BK, Raisley EK, Lowe DC, Bian J, Korpenfelt SL, Benestad SL, Telling GC. Novel Prion Strain as Cause of Chronic Wasting Disease in a Moose, Finland. Emerging Infectious Diseases. 29: 323-332. PMID 36692340 DOI: 10.3201/eid2902.220882  0.476
2022 Vidal E, Sánchez-Martín MA, Eraña H, Lázaro SP, Pérez-Castro MA, Otero A, Charco JM, Marín B, López-Moreno R, Díaz-Domínguez CM, Geijo M, Ordóñez M, Cantero G, di Bari M, Lorenzo NL, ... ... Telling G, et al. Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model. Acta Neuropathologica Communications. 10: 179. PMID 36514160 DOI: 10.1186/s40478-022-01477-7  0.535
2022 Mays CE, Trinh THT, Telling G, Kang HE, Ryou C. Endoproteolysis of cellular prion protein by plasmin hinders propagation of prions. Frontiers in Molecular Neuroscience. 15: 990136. PMID 36117913 DOI: 10.3389/fnmol.2022.990136  0.419
2022 Wagner K, Pierce R, Gordon E, Hay A, Lessard A, Telling GC, Ballard JR, Moreno JA, Zabel MD. Tissue-Specific Biochemical Differences Between Chronic Wasting Disease Prions Isolated From Free-Ranging White-Tailed Deer (Odocoileus virginianus). The Journal of Biological Chemistry. 101834. PMID 35304100 DOI: 10.1016/j.jbc.2022.101834  0.484
2021 Bian J, Kim S, Kane SJ, Crowell J, Sun JL, Christiansen J, Saijo E, Moreno JA, DiLisio J, Burnett E, Pritzkow S, Gorski D, Soto C, Kreeger TJ, Balachandran A, ... ... Telling GC, et al. Adaptive selection of a prion strain conformer corresponding to established North American CWD during propagation of novel emergent Norwegian strains in mice expressing elk or deer prion protein. Plos Pathogens. 17: e1009748. PMID 34310663 DOI: 10.1371/journal.ppat.1009748  0.5
2021 Pritzkow S, Gorski D, Ramirez F, Telling GC, Benestad SL, Soto C. North American and Norwegian Chronic Wasting Disease prions exhibit different potential for interspecies transmission and zoonotic risk. The Journal of Infectious Diseases. PMID 34302479 DOI: 10.1093/infdis/jiab385  0.425
2020 Nonno R, Di Bari MA, Pirisinu L, D'Agostino C, Vanni I, Chiappini B, Marcon S, Riccardi G, Tran L, Vikøren T, Våge J, Madslien K, Mitchell G, Telling GC, Benestad SL, et al. Studies in bank voles reveal strain differences between chronic wasting disease prions from Norway and North America. Proceedings of the National Academy of Sciences of the United States of America. PMID 33229531 DOI: 10.1073/pnas.2013237117  0.341
2020 Yu CG, Bondada V, Joshi A, Reneer DV, Telling G, Saatman KE, Geddes JW. Calpastatin overexpression protects against excitotoxic hippocampal injury and traumatic spinal cord injury. Journal of Neurotrauma. PMID 32718209 DOI: 10.1089/Neu.2020.7122  0.325
2020 Kang HE, Bian J, Kane SJ, Kim S, Selwyn V, Crowell J, Bartz JC, Telling GC. Incomplete glycosylation during prion infection unmasks a prion protein epitope that facilitates prion detection and strain discrimination. The Journal of Biological Chemistry. PMID 32513872 DOI: 10.1074/Jbc.Ra120.012796  0.511
2020 Parrie LE, Crowell JAE, Moreno JA, Suinn SS, Telling GC, Bessen RA. The cellular prion protein promotes neuronal regeneration after acute nasotoxic injury. Prion. 14: 31-41. PMID 31950869 DOI: 10.1080/19336896.2020.1714373  0.337
2019 Kramm C, Gomez-Gutierrez R, Soto C, Telling G, Nichols T, Morales R. In Vitro detection of Chronic Wasting Disease (CWD) prions in semen and reproductive tissues of white tailed deer bucks (Odocoileus virginianus). Plos One. 14: e0226560. PMID 31887141 DOI: 10.1371/Journal.Pone.0226560  0.413
2019 Slapšak U, Salzano G, Ilc G, Giachin G, Bian J, Telling G, Legname G, Plavec J. Unique Structural Features of Mule Deer Prion Protein Provide Insights into Chronic Wasting Disease. Acs Omega. 4: 19913-19924. PMID 31788624 DOI: 10.1021/acsomega.9b02824  0.411
2019 Telling GC. Breakthroughs in antemortem diagnosis of neurodegenerative diseases. Proceedings of the National Academy of Sciences of the United States of America. PMID 31666323 DOI: 10.1073/Pnas.1917054116  0.404
2019 Eraña H, Charco JM, Di Bari MA, Díaz-Domínguez CM, López-Moreno R, Vidal E, González-Miranda E, Pérez-Castro MA, García-Martínez S, Bravo S, Fernández-Borges N, Geijo M, D'Agostino C, Garrido J, Bian J, ... ... Telling GC, et al. Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies. Plos Pathogens. 15: e1008117. PMID 31644574 DOI: 10.1371/Journal.Ppat.1008117  0.8
2019 Mays CE, Armijo E, Morales R, Kramm C, Flores A, Tiwari A, Bian J, Telling GC, Pandita TK, Hunt CR, Soto C. Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70). The Journal of Biological Chemistry. PMID 31320473 DOI: 10.1074/Jbc.Ra118.006186  0.515
2019 Camacho MV, Telling G, Kong Q, Gambetti P, Notari S. Role of prion protein glycosylation in replication of human prions by protein misfolding cyclic amplification. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31249376 DOI: 10.1038/S41374-019-0282-1  0.542
2019 Bian J, Christiansen JR, Moreno JA, Kane SJ, Khaychuk V, Gallegos J, Kim S, Telling GC. Primary structural differences at residue 226 of deer and elk PrP dictate selection of distinct CWD prion strains in gene-targeted mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 31147460 DOI: 10.1073/Pnas.1903947116  0.8
2019 Lyon A, Mays CE, Borriello F, Telling GC, Soto C, Pritzkow S. Application of PMCA to screen for prion infection in a human cell line used to produce biological therapeutics. Scientific Reports. 9: 4847. PMID 30890734 DOI: 10.1038/S41598-019-41055-X  0.401
2018 Ricci A, Allende A, Bolton D, Chemaly M, Davies R, Fernández Escámez PS, Gironés R, Herman L, Koutsoumanis K, Lindqvist R, Nørrung B, Robertson L, Ru G, Sanaa M, ... ... Telling GC, et al. Scientific opinion on chronic wasting disease (II). Efsa Journal. European Food Safety Authority. 16: e05132. PMID 32625679 DOI: 10.2903/J.Efsa.2018.5132  0.404
2018 Benestad SL, Telling GC. Chronic wasting disease: an evolving prion disease of cervids. Handbook of Clinical Neurology. 153: 135-151. PMID 29887133 DOI: 10.1016/B978-0-444-63945-5.00008-8  0.487
2018 Davenport KA, Christiansen JR, Bian J, Young M, Gallegos J, Kim S, Balachandran A, Mathiason CK, Hoover EA, Telling GC. Comparative analysis of prions in nervous and lymphoid tissues of chronic wasting disease-infected cervids. The Journal of General Virology. PMID 29580373 DOI: 10.1099/Jgv.0.001053  0.798
2018 Parrie LE, Crowell JAE, Telling GC, Bessen RA. The cellular prion protein promotes olfactory sensory neuron survival and axon targeting during adult neurogenesis. Developmental Biology. PMID 29577883 DOI: 10.1016/J.Ydbio.2018.03.012  0.367
2018 Yuan Q, Telling G, Bartelt-Hunt SL, Bartz JC. Dehydration of prions on environmentally relevant surfaces protects them from inactivation by freezing and thawing. Journal of Virology. PMID 29386284 DOI: 10.1128/Jvi.02191-17  0.503
2017 Ricci A, Allende A, Bolton D, Chemaly M, Davies R, Fernández Escámez PS, Gironés R, Herman L, Koutsoumanis K, Lindqvist R, Nørrung B, Robertson L, Sanaa M, Skandamis P, ... ... Telling GC, et al. Chronic wasting disease (CWD) in cervids. Efsa Journal. European Food Safety Authority. 15: e04667. PMID 32625260 DOI: 10.2903/J.Efsa.2017.4667  0.444
2017 Kane SJ, Farley TK, Gordon EO, Estep J, Bender HR, Moreno JA, Bartz J, Telling GC, Pickering MC, Zabel MD. Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis. Journal of Immunology (Baltimore, Md. : 1950). PMID 29070671 DOI: 10.4049/Jimmunol.1701100  0.577
2017 Davenport KA, Hoover CE, Bian J, Telling GC, Mathiason CK, Hoover EA. PrPC expression and prion seeding activity in the alimentary tract and lymphoid tissue of deer. Plos One. 12: e0183927. PMID 28880938 DOI: 10.1371/Journal.Pone.0183927  0.436
2017 Moreno JA, Telling GC. Insights into Mechanisms of Transmission and Pathogenesis from Transgenic Mouse Models of Prion Diseases. Methods in Molecular Biology (Clifton, N.J.). 1658: 219-252. PMID 28861793 DOI: 10.1007/978-1-4939-7244-9_16  0.591
2017 Hannaoui S, Amidian S, Cheng YC, Duque Velásquez C, Dorosh L, Law S, Telling G, Stepanova M, McKenzie D, Wille H, Gilch S. Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency. Plos Pathogens. 13: e1006553. PMID 28800624 DOI: 10.1371/Journal.Ppat.1006553  0.6
2017 Iwamaru Y, Mathiason CK, Telling GC, Hoover EA. Chronic wasting disease prion infection of differentiated neurospheres. Prion. 1-7. PMID 28762865 DOI: 10.1080/19336896.2017.1336273  0.552
2017 Moreno JA, Telling GC. Molecular Mechanisms of Chronic Wasting Disease Prion Propagation. Cold Spring Harbor Perspectives in Medicine. PMID 28193766 DOI: 10.1101/Cshperspect.A024448  0.494
2017 Bian J, Khaychuk V, Angers RC, Fernández-Borges N, Vidal E, Meyerett-Reid C, Kim S, Calvi CL, Bartz JC, Hoover EA, Agrimi U, Richt JA, Castilla J, Telling GC. Prion replication without host adaptation during interspecies transmissions. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096357 DOI: 10.1073/Pnas.1611891114  0.842
2017 Waqas M, Lee HM, Kim J, Telling G, Kim JK, Kim DH, Ryou C. Effect of poly-L-arginine in inhibiting scrapie prion protein of cultured cells. Molecular and Cellular Biochemistry. PMID 28063003 DOI: 10.1007/S11010-016-2916-6  0.47
2016 Wyckoff AC, Kane S, Lockwood K, Seligman J, Michel B, Hill D, Ortega A, Mangalea MR, Telling GC, Miller MW, Vercauteren K, Zabel MD. Clay Components in Soil Dictate Environmental Stability and Bioavailability of Cervid Prions in Mice. Frontiers in Microbiology. 7: 1885. PMID 27933048 DOI: 10.3389/Fmicb.2016.01885  0.422
2015 Davenport KA, Henderson DM, Bian J, Telling GC, Mathiason CK, Hoover EA. Insights into Chronic Wasting Disease and Bovine Spongiform Encephalopathy Species Barriers by Use of Real-Time Conversion. Journal of Virology. 89: 9524-31. PMID 26157118 DOI: 10.1128/Jvi.01439-15  0.479
2015 Telling G. Neurodegeneration: Evolved protection against human prions. Nature. 522: 423-4. PMID 26061767 DOI: 10.1038/Nature14534  0.574
2015 Pritzkow S, Morales R, Moda F, Khan U, Telling GC, Hoover E, Soto C. Grass plants bind, retain, uptake, and transport infectious prions. Cell Reports. 11: 1168-75. PMID 25981035 DOI: 10.1016/J.Celrep.2015.04.036  0.433
2015 Yuan Q, Eckland T, Telling G, Bartz J, Bartelt-Hunt S. Mitigation of prion infectivity and conversion capacity by a simulated natural process--repeated cycles of drying and wetting. Plos Pathogens. 11: e1004638. PMID 25665187 DOI: 10.1371/Journal.Ppat.1004638  0.385
2015 Yuan Q, Eckland T, Telling G, Bartz J, Bartelt-Hunt S. Repeated cycles of drying and wetting extend the incubation period of prion infection. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1004638.G008  0.316
2015 Yuan Q, Eckland T, Telling G, Bartz J, Bartelt-Hunt S. Reduced total protein abundance in HY TME brain homogenate. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1004638.G001  0.32
2014 Angers R, Christiansen J, Nalls AV, Kang HE, Hunter N, Hoover E, Mathiason CK, Sheetz M, Telling GC. Structural effects of PrP polymorphisms on intra- and interspecies prion transmission Proceedings of the National Academy of Sciences of the United States of America. 111: 11169-11174. PMID 25034251 DOI: 10.1073/Pnas.1404739111  0.843
2014 Bian J, Kang HE, Telling GC. Quinacrine promotes replication and conformational mutation of chronic wasting disease prions. Proceedings of the National Academy of Sciences of the United States of America. 111: 6028-33. PMID 24711410 DOI: 10.1073/Pnas.1322377111  0.608
2014 Mays CE, Kim C, Haldiman T, van der Merwe J, Lau A, Yang J, Grams J, Di Bari MA, Nonno R, Telling GC, Kong Q, Langeveld J, McKenzie D, Westaway D, Safar JG. Prion disease tempo determined by host-dependent substrate reduction. The Journal of Clinical Investigation. 124: 847-58. PMID 24430187 DOI: 10.1172/Jci72241  0.579
2014 Vickery CM, Lockey R, Holder TM, Thorne L, Beck KE, Wilson C, Denyer M, Sheehan J, Marsh S, Webb PR, Dexter I, Norman A, Popescu E, Schneider A, Holden P, ... ... Telling GC, et al. Assessing the susceptibility of transgenic mice overexpressing deer prion protein to bovine spongiform encephalopathy. Journal of Virology. 88: 1830-3. PMID 24257620 DOI: 10.1128/Jvi.02762-13  0.58
2013 Saijo E, Kang HE, Bian J, Bowling KG, Browning S, Kim S, Hunter N, Telling GC. Epigenetic dominance of prion conformers. Plos Pathogens. 9: e1003692. PMID 24204258 DOI: 10.1371/Journal.Ppat.1003692  0.749
2013 Michel B, Ferguson A, Johnson T, Bender H, Meyerett-Reid C, Wyckoff AC, Pulford B, Telling GC, Zabel MD. Complement protein C3 exacerbates prion disease in a mouse model of chronic wasting disease. International Immunology. 25: 697-702. PMID 24038599 DOI: 10.1093/Intimm/Dxt034  0.573
2013 Piccardo P, King D, Telling G, Manson JC, Barron RM. Dissociation of prion protein amyloid seeding from transmission of a spongiform encephalopathy. Journal of Virology. 87: 12349-56. PMID 24027305 DOI: 10.1128/Jvi.00673-13  0.654
2013 Haldiman T, Kim C, Cohen Y, Chen W, Blevins J, Qing L, Cohen ML, Langeveld J, Telling GC, Kong Q, Safar JG. Co-existence of distinct prion types enables conformational evolution of human PrPSc by competitive selection. The Journal of Biological Chemistry. 288: 29846-61. PMID 23974118 DOI: 10.1074/Jbc.M113.500108  0.499
2013 Nichols TA, Spraker TR, Rigg TD, Meyerett-Reid C, Hoover C, Michel B, Bian J, Hoover E, Gidlewski T, Balachandran A, O'Rourke K, Telling GC, Bowen R, Zabel MD, VerCauteren KC. Intranasal inoculation of white-tailed deer (Odocoileus virginianus) with lyophilized chronic wasting disease prion particulate complexed to montmorillonite clay. Plos One. 8: e62455. PMID 23671598 DOI: 10.1371/Journal.Pone.0062455  0.484
2013 Telling GC. The importance of prions. Plos Pathogens. 9: e1003090. PMID 23382670 DOI: 10.1371/Journal.Ppat.1003090  0.491
2013 Schoch KM, von Reyn CR, Bian J, Telling GC, Meaney DF, Saatman KE. Brain injury-induced proteolysis is reduced in a novel calpastatin-overexpressing transgenic mouse. Journal of Neurochemistry. 125: 909-20. PMID 23305291 DOI: 10.1111/Jnc.12144  0.371
2012 Michel B, Ferguson A, Johnson T, Bender H, Meyerett-Reid C, Pulford B, von Teichman A, Seelig D, Weis JH, Telling GC, Aguzzi A, Zabel MD. Genetic depletion of complement receptors CD21/35 prevents terminal prion disease in a mouse model of chronic wasting disease. Journal of Immunology (Baltimore, Md. : 1950). 189: 4520-7. PMID 23002439 DOI: 10.4049/Jimmunol.1201579  0.534
2012 Kang HE, Weng CC, Saijo E, Saylor V, Bian J, Kim S, Ramos L, Angers R, Langenfeld K, Khaychuk V, Calvi C, Bartz J, Hunter N, Telling GC. Characterization of conformation-dependent prion protein epitopes. The Journal of Biological Chemistry. 287: 37219-32. PMID 22948149 DOI: 10.1074/Jbc.M112.395921  0.789
2012 Kim C, Haldiman T, Surewicz K, Cohen Y, Chen W, Blevins J, Sy MS, Cohen M, Kong Q, Telling GC, Surewicz WK, Safar JG. Small protease sensitive oligomers of PrPSc in distinct human prions determine conversion rate of PrP(C). Plos Pathogens. 8: e1002835. PMID 22876179 DOI: 10.1371/Journal.Ppat.1002835  0.585
2012 Michel B, Meyerett-Reid C, Johnson T, Ferguson A, Wyckoff C, Pulford B, Bender H, Avery A, Telling G, Dow S, Zabel MD. Incunabular immunological events in prion trafficking. Scientific Reports. 2: 440. PMID 22679554 DOI: 10.1038/Srep00440  0.344
2012 Nichols TA, Spraker TR, Gidlewski T, Powers JG, Telling GC, VerCauteren KC, Zabel MD. Detection of prion protein in the cerebrospinal fluid of elk (Cervus canadensis nelsoni) with chronic wasting disease using protein misfolding cyclic amplification. Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 24: 746-9. PMID 22621952 DOI: 10.1177/1040638712448060  0.455
2012 Pulford B, Spraker TR, Wyckoff AC, Meyerett C, Bender H, Ferguson A, Wyatt B, Lockwood K, Powers J, Telling GC, Wild MA, Zabel MD. Detection of PrPCWD in feces from naturally exposed Rocky Mountain elk (Cervus elaphus nelsoni) using protein misfolding cyclic amplification. Journal of Wildlife Diseases. 48: 425-34. PMID 22493117 DOI: 10.7589/0090-3558-48.2.425  0.469
2012 Haley NJ, Mathiason CK, Carver S, Telling GC, Zabel MD, Hoover EA. Sensitivity of protein misfolding cyclic amplification versus immunohistochemistry in ante-mortem detection of chronic wasting disease. The Journal of General Virology. 93: 1141-50. PMID 22278825 DOI: 10.1099/Vir.0.039073-0  0.41
2012 Telling GC. Transgenic studies of prion diseases. Methods in Molecular Medicine. 59: 111-27. PMID 21374501 DOI: 10.1385/1-59259-134-5:111  0.568
2011 Seelig DM, Mason GL, Telling GC, Hoover EA. Chronic wasting disease prion trafficking via the autonomic nervous system. The American Journal of Pathology. 179: 1319-28. PMID 21777560 DOI: 10.1016/J.Ajpath.2011.05.057  0.621
2011 Telling GC. Transgenic mouse models and prion strains. Topics in Current Chemistry. 305: 79-99. PMID 21769720 DOI: 10.1007/128_2011_166  0.416
2011 Kurt TD, Seelig DM, Schneider JR, Johnson CJ, Telling GC, Heisey DM, Hoover EA. Alteration of the chronic wasting disease species barrier by in vitro prion amplification. Journal of Virology. 85: 8528-37. PMID 21697475 DOI: 10.1128/Jvi.00809-11  0.553
2011 Saijo E, Scheff SW, Telling GC. Unaltered prion protein expression in Alzheimer disease patients. Prion. 5: 109-16. PMID 21654203 DOI: 10.4161/Pri.5.2.16355  0.395
2011 Haley NJ, Mathiason CK, Carver S, Zabel M, Telling GC, Hoover EA. Detection of chronic wasting disease prions in salivary, urinary, and intestinal tissues of deer: potential mechanisms of prion shedding and transmission. Journal of Virology. 85: 6309-18. PMID 21525361 DOI: 10.1128/Jvi.00425-11  0.494
2011 Mays CE, Yeom J, Kang HE, Bian J, Khaychuk V, Kim Y, Bartz JC, Telling GC, Ryou C. In vitro amplification of misfolded prion protein using lysate of cultured cells. Plos One. 6: e18047. PMID 21464935 DOI: 10.1371/Journal.Pone.0018047  0.8
2011 Barria MA, Telling GC, Gambetti P, Mastrianni JA, Soto C. Generation of a new form of human PrP(Sc) in vitro by interspecies transmission from cervid prions. The Journal of Biological Chemistry. 286: 7490-5. PMID 21209079 DOI: 10.1074/Jbc.M110.198465  0.572
2011 Denkers ND, Telling GC, Hoover EA. Minor oral lesions facilitate transmission of chronic wasting disease. Journal of Virology. 85: 1396-9. PMID 21084472 DOI: 10.1128/Jvi.01655-10  0.447
2010 Telling GC. Nucleic acid-free mutation of prion strains. Prion. 4: 252-5. PMID 20948302 DOI: 10.4161/Pri.4.4.13675  0.429
2010 Bian J, Napier D, Khaychuck V, Angers R, Graham C, Telling G. Cell-based quantification of chronic wasting disease prions Journal of Virology. 84: 8322-8326. PMID 20519392 DOI: 10.1128/Jvi.00633-10  0.829
2010 Angers RC, Kang HE, Napier D, Browning S, Seward T, Mathiason C, Balachandran A, McKenzie D, Castilla J, Soto C, Jewell J, Graham C, Hoover EA, Telling GC. Prion strain mutation determined by prion protein conformational compatibility and primary structure. Science (New York, N.Y.). 328: 1154-8. PMID 20466881 DOI: 10.1126/Science.1187107  0.819
2010 Seelig DM, Mason GL, Telling GC, Hoover EA. Pathogenesis of chronic wasting disease in cervidized transgenic mice. The American Journal of Pathology. 176: 2785-97. PMID 20395435 DOI: 10.2353/Ajpath.2010.090710  0.627
2010 Mathiason CK, Hayes-Klug J, Hays SA, Powers J, Osborn DA, Dahmes SJ, Miller KV, Warren RJ, Mason GL, Telling GC, Young AJ, Hoover EA. B cells and platelets harbor prion infectivity in the blood of deer infected with chronic wasting disease. Journal of Virology. 84: 5097-107. PMID 20219916 DOI: 10.1128/Jvi.02169-09  0.421
2010 Zou WQ, Langeveld J, Xiao X, Chen S, McGeer PL, Yuan J, Payne MC, Kang HE, McGeehan J, Sy MS, Greenspan NS, Kaplan D, Wang GX, Parchi P, Hoover E, ... ... Telling G, et al. PrP conformational transitions alter species preference of a PrP-specific antibody. The Journal of Biological Chemistry. 285: 13874-84. PMID 20194495 DOI: 10.1074/Jbc.M109.088831  0.428
2010 Denkers ND, Seelig DM, Telling GC, Hoover EA. Aerosol and nasal transmission of chronic wasting disease in cervidized mice. The Journal of General Virology. 91: 1651-8. PMID 20164261 DOI: 10.1099/Vir.0.017335-0  0.585
2009 Haley NJ, Mathiason CK, Zabel MD, Telling GC, Hoover EA. Detection of sub-clinical CWD infection in conventional test-negative deer long after oral exposure to urine and feces from CWD+ deer. Plos One. 4: e7990. PMID 19956732 DOI: 10.1371/Journal.Pone.0007990  0.508
2009 Nichols TA, Pulford B, Wyckoff AC, Meyerett C, Michel B, Gertig K, Hoover EA, Jewell JE, Telling GC, Zabel MD. Detection of protease-resistant cervid prion protein in water from a CWD-endemic area. Prion. 3: 171-83. PMID 19823039 DOI: 10.4161/Pri.3.3.9819  0.404
2009 Mays CE, Titlow W, Seward T, Telling GC, Ryou C. Enhancement of protein misfolding cyclic amplification by using concentrated cellular prion protein source. Biochemical and Biophysical Research Communications. 388: 306-10. PMID 19664595 DOI: 10.1016/J.Bbrc.2009.07.163  0.525
2009 Angers RC, Seward TS, Napier D, Green M, Hoover E, Spraker T, O'Rourke K, Balachandran A, Telling GC. Chronic wasting disease prions in elk antler velvet. Emerging Infectious Diseases. 15: 696-703. PMID 19402954 DOI: 10.3201/Eid1505.081458  0.858
2009 Haley NJ, Seelig DM, Zabel MD, Telling GC, Hoover EA. Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay. Plos One. 4: e4848. PMID 19293928 DOI: 10.1371/Journal.Pone.0004848  0.593
2009 Kurt TD, Telling GC, Zabel MD, Hoover EA. Trans-species amplification of PrP(CWD) and correlation with rigid loop 170N. Virology. 387: 235-43. PMID 19269662 DOI: 10.1016/J.Virol.2009.02.025  0.458
2008 Meyerett C, Michel B, Pulford B, Spraker TR, Nichols TA, Johnson T, Kurt T, Hoover EA, Telling GC, Zabel MD. In vitro strain adaptation of CWD prions by serial protein misfolding cyclic amplification. Virology. 382: 267-76. PMID 18952250 DOI: 10.1016/J.Virol.2008.09.023  0.443
2008 Saunders SE, Bartz JC, Telling GC, Bartelt-Hunt SL. Environmentally-relevant forms of the prion protein. Environmental Science & Technology. 42: 6573-9. PMID 18800532 DOI: 10.1021/Es800590K  0.539
2008 Green KM, Castilla J, Seward TS, Napier DL, Jewell JE, Soto C, Telling GC. Accelerated high fidelity prion amplification within and across prion species barriers. Plos Pathogens. 4: e1000139. PMID 18769716 DOI: 10.1371/Journal.Ppat.1000139  0.757
2008 Telling GC. Transgenic mouse models of prion diseases. Methods in Molecular Biology (Clifton, N.J.). 459: 249-63. PMID 18576160 DOI: 10.1007/978-1-59745-234-2_17  0.571
2008 Green KM, Browning SR, Seward TS, Jewell JE, Ross DL, Green MA, Williams ES, Hoover EA, Telling GC. The elk PRNP codon 132 polymorphism controls cervid and scrapie prion propagation. The Journal of General Virology. 89: 598-608. PMID 18198392 DOI: 10.1099/Vir.0.83168-0  0.768
2007 Kurt TD, Perrott MR, Wilusz CJ, Wilusz J, Supattapone S, Telling GC, Zabel MD, Hoover EA. Efficient in vitro amplification of chronic wasting disease PrPRES. Journal of Virology. 81: 9605-8. PMID 17553879 DOI: 10.1128/Jvi.00635-07  0.773
2007 Nazor KE, Seward T, Telling GC. Motor behavioral and neuropathological deficits in mice deficient for normal prion protein expression. Biochimica Et Biophysica Acta. 1772: 645-53. PMID 17531449 DOI: 10.1016/J.Bbadis.2007.04.004  0.815
2006 Mathiason CK, Powers JG, Dahmes SJ, Osborn DA, Miller KV, Warren RJ, Mason GL, Hays SA, Hayes-Klug J, Seelig DM, Wild MA, Wolfe LL, Spraker TR, Miller MW, Sigurdson CJ, ... Telling GC, et al. Infectious prions in the saliva and blood of deer with chronic wasting disease. Science (New York, N.Y.). 314: 133-6. PMID 17023660 DOI: 10.1126/Science.1132661  0.457
2006 Angers RC, Browning SR, Seward TS, Sigurdson CJ, Miller MW, Hoover EA, Telling GC. Prions in skeletal muscles of deer with chronic wasting disease. Science (New York, N.Y.). 311: 1117. PMID 16439622 DOI: 10.1126/Science.1122864  0.819
2006 Bian J, Nazor KE, Angers R, Jernigan M, Seward T, Centers A, Green M, Telling GC. GFP-tagged PrP supports compromised prion replication in transgenic mice. Biochemical and Biophysical Research Communications. 340: 894-900. PMID 16386707 DOI: 10.1016/J.Bbrc.2005.12.085  0.8
2005 Telling G. Anchors away--of plaques and pathology in prion disease. The New England Journal of Medicine. 353: 1177-9. PMID 16162891 DOI: 10.1056/Nejmcibr052527  0.473
2005 Nazor KE, Kuhn F, Seward T, Green M, Zwald D, Pürro M, Schmid J, Biffiger K, Power AM, Oesch B, Raeber AJ, Telling GC. Immunodetection of disease-associated mutant PrP, which accelerates disease in GSS transgenic mice. The Embo Journal. 24: 2472-80. PMID 15962001 DOI: 10.1038/Sj.Emboj.7600717  0.835
2004 Browning SR, Mason GL, Seward T, Green M, Eliason GA, Mathiason C, Miller MW, Williams ES, Hoover E, Telling GC. Transmission of prions from mule deer and elk with chronic wasting disease to transgenic mice expressing cervid PrP. Journal of Virology. 78: 13345-50. PMID 15542685 DOI: 10.1128/Jvi.78.23.13345-13350.2004  0.775
2004 Moroncini G, Kanu N, Solforosi L, Abalos G, Telling GC, Head M, Ironside J, Brockes JP, Burton DR, Williamson RA. Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc. Proceedings of the National Academy of Sciences of the United States of America. 101: 10404-9. PMID 15240877 DOI: 10.1073/Pnas.0403522101  0.435
2004 Telling GC. The mechanism of prion strain propagation. Genome Biology. 5: 222. PMID 15128438 DOI: 10.1186/Gb-2004-5-5-222  0.46
2004 Yadavalli R, Guttmann RP, Seward T, Centers AP, Williamson RA, Telling GC. Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation. The Journal of Biological Chemistry. 279: 21948-56. PMID 15026410 DOI: 10.1074/Jbc.M400793200  0.469
2003 Korth C, Kaneko K, Groth D, Heye N, Telling G, Mastrianni J, Parchi P, Gambetti P, Will R, Ironside J, Heinrich C, Tremblay P, DeArmond SJ, Prusiner SB. Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene. Proceedings of the National Academy of Sciences of the United States of America. 100: 4784-9. PMID 12684540 DOI: 10.1073/Pnas.2627989100  0.653
2002 Bosque PJ, Ryou C, Telling G, Peretz D, Legname G, DeArmond SJ, Prusiner SB. Prions in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 99: 3812-7. PMID 11904434 DOI: 10.1073/Pnas.052707499  0.619
2002 Connolly JG, Tate RJ, Telling GC, Fraser J, Brown D, Head MW. Expression of cellular prion protein in Xenopus oocytes Biochemical Society Transactions. 30: A82-A82. DOI: 10.1042/Bst030A082A  0.358
2001 Mastrianni JA, Capellari S, Telling GC, Han D, Bosque P, Prusiner SB, DeArmond SJ. Inherited prion disease caused by the V210I mutation: transmission to transgenic mice. Neurology. 57: 2198-205. PMID 11756597 DOI: 10.1212/Wnl.57.12.2198  0.669
2001 Telling G. Protein-based PCR for prion diseases? Nature Medicine. 7: 778-9. PMID 11433339 DOI: 10.1038/89895  0.489
2001 Campbell S, Dennehy U, Telling G. Analyzing the influence of PrP primary structure on prion pathogenesis in transgenic mice. Archives of Virology. Supplementum. 87-94. PMID 11214937 DOI: 10.1007/978-3-7091-6308-5_7  0.557
2000 Telling GC. Prion protein genes and prion diseases: Studies in transgenic mice Neuropathology and Applied Neurobiology. 26: 209-220. PMID 10886679 DOI: 10.1046/j.1365-2990.2000.00253.x  0.532
1999 Mastrianni JA, Nixon R, Layzer R, Telling GC, Han D, DeArmond SJ, Prusiner SB. Prion protein conformation in a patient with sporadic fatal insomnia. The New England Journal of Medicine. 340: 1630-8. PMID 10341275 DOI: 10.1056/Nejm199905273402104  0.632
1998 Fisher E, Telling G, Collinge J. Prions and the prion disorders. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 497-502. PMID 9657843 DOI: 10.1007/S003359900807  0.346
1997 Muramoto T, DeArmond SJ, Scott M, Telling GC, Cohen FE, Prusiner SB. Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an alpha-helix. Nature Medicine. 3: 750-5. PMID 9212101 DOI: 10.1038/nm0797-750  0.581
1997 Telling GC, Tremblay P, Torchia M, Dearmond SJ, Cohen FE, Prusiner SB. N-terminally tagged prion protein supports prion propagation in transgenic mice. Protein Science : a Publication of the Protein Society. 6: 825-33. PMID 9098892 DOI: 10.1002/pro.5560060409  0.593
1996 Bamborough P, Wille H, Telling GC, Yehiely F, Prusiner SB, Cohen FE. Prion protein structure and scrapie replication: theoretical, spectroscopic, and genetic investigations. Cold Spring Harbor Symposia On Quantitative Biology. 61: 495-509. PMID 9246476 DOI: 10.1101/Sqb.1996.061.01.050  0.424
1996 Telling GC, Parchi P, DeArmond SJ, Cortelli P, Montagna P, Gabizon R, Mastrianni J, Lugaresi E, Gambetti P, Prusiner SB. Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science (New York, N.Y.). 274: 2079-82. PMID 8953038 DOI: 10.1126/Science.274.5295.2079  0.659
1996 Telling GC, Haga T, Torchia M, Tremblay P, DeArmond SJ, Prusiner SB. Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice. Genes & Development. 10: 1736-50. PMID 8698234 DOI: 10.1101/Gad.10.14.1736  0.616
1996 Scott MR, Telling GC, Prusiner SB. Transgenetics and gene targeting in studies of prion diseases. Current Topics in Microbiology and Immunology. 207: 95-123. PMID 8575209 DOI: 10.1007/978-3-642-60983-1_8  0.545
1996 Gabizon R, Telling G, Meiner Z, Halimi M, Kahana I, Prusiner SB. Insoluble wild-type and protease-resistant mutant prion protein in brains of patients with inherited prion disease. Nature Medicine. 2: 59-64. PMID 8564843 DOI: 10.1038/nm0196-59  0.569
1996 Prusiner SB, Telling G, Cohen FE, DeArmond SJ. Prion diseases of humans and animals Seminars in Virology. 7: 159-173. DOI: 10.1006/smvy.1996.0021  0.548
1995 Telling GC, Scott M, Mastrianni J, Gabizon R, Torchia M, Cohen FE, DeArmond SJ, Prusiner SB. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell. 83: 79-90. PMID 7553876 DOI: 10.1016/0092-8674(95)90236-8  0.62
1994 Telling GC, Scott M, Hsiao KK, Foster D, Yang SL, Torchia M, Sidle KC, Collinge J, DeArmond SJ, Prusiner SB. Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 9936-40. PMID 7937921 DOI: 10.1073/Pnas.91.21.9936  0.667
1994 Carlson GA, Ebeling C, Yang SL, Telling G, Torchia M, Groth D, Westaway D, DeArmond SJ, Prusiner SB. Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 5690-4. PMID 7911243 DOI: 10.1073/Pnas.91.12.5690  0.63
1993 Borchelt DR, Rogers M, Stahl N, Telling G, Prusiner SB. Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor. Glycobiology. 3: 319-29. PMID 7691278 DOI: 10.1093/Glycob/3.4.319  0.727
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