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Tristan Frum, Ph.D. - Publications

Affiliations: 
2014 Molecular Cell and Developmental Biology University of California, Santa Cruz, Santa Cruz, CA, United States 
Area:
Human Development, Cell Biology
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kruger RE, Frum T, Brumm AS, Hickey SL, Niakan KK, Aziz F, Shammami MA, Roberts JG, Ralston A. Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential prior to implantation in mouse. Development (Cambridge, England). PMID 38752427 DOI: 10.1242/dev.202377  0.675
2024 Kruger RE, Frum T, Brumm AS, Hickey SL, Niakan KK, Aziz F, Shammami MA, Roberts JG, Ralston A. is essential for epiblast scaling and morphogenesis after implantation, but nonessential prior to implantation in the mouse. Biorxiv : the Preprint Server For Biology. PMID 38328075 DOI: 10.1101/2024.01.23.576717  0.67
2023 Li L, Lai F, Hu X, Liu B, Lu X, Lin Z, Liu L, Xiang Y, Frum T, Halbisen MA, Chen F, Fan Q, Ralston A, Xie W. Multifaceted SOX2-chromatin interaction underpins pluripotency progression in early embryos. Science (New York, N.Y.). 382: eadi5516. PMID 38096290 DOI: 10.1126/science.adi5516  0.699
2023 Frum T, Hsu PP, Hein RFC, Conchola AS, Zhang CJ, Utter OR, Anand A, Zhang Y, Clark SG, Glass I, Sexton JZ, Spence JR. Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung. Npj Regenerative Medicine. 8: 48. PMID 37689780 DOI: 10.1038/s41536-023-00325-z  0.427
2023 Conchola AS, Frum T, Xiao Z, Hsu PP, Kaur K, Downey MS, Hein RFC, Miller AJ, Tsai YH, Wu A, Holloway EM, Anand A, Murthy PKL, Glass I, Tata PR, et al. Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung. Proceedings of the National Academy of Sciences of the United States of America. 120: e2210113120. PMID 37279279 DOI: 10.1073/pnas.2210113120  0.382
2023 Frum T, Hsu PP, Hein RFC, Conchola AS, Zhang CJ, Utter OR, Anand A, Zhang Y, Clark SG, Glass I, Sexton JZ, Spence JR. Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung. Biorxiv : the Preprint Server For Biology. PMID 37205521 DOI: 10.1101/2023.05.05.539573  0.424
2022 Hein RFC, Conchola AS, Fine AS, Xiao Z, Frum T, Brastrom LK, Akinwale MA, Childs CJ, Tsai YH, Holloway EM, Huang S, Mahoney J, Heemskerk I, Spence JR. Stable iPSC-derived NKX2-1+ lung bud tip progenitor organoids give rise to airway and alveolar cell types. Development (Cambridge, England). 149. PMID 36039869 DOI: 10.1242/dev.200693  0.386
2022 Hein RFC, Wu JH, Holloway EM, Frum T, Conchola AS, Tsai YH, Wu A, Fine AS, Miller AJ, Szenker-Ravi E, Yan KS, Kuo CJ, Glass I, Reversade B, Spence JR. R-SPONDIN2 mesenchymal cells form the bud tip progenitor niche during human lung development. Developmental Cell. PMID 35679862 DOI: 10.1016/j.devcel.2022.05.010  0.371
2021 Yan B, Freiwald T, Chauss D, Wang L, West E, Mirabelli C, Zhang CJ, Nichols EM, Malik N, Gregory R, Bantscheff M, Ghidelli-Disse S, Kolev M, Frum T, Spence JR, et al. SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. Science Immunology. 6. PMID 33827897 DOI: 10.1126/sciimmunol.abg0833  0.32
2020 Frum T, Spence JR. hPSC-derived organoids: models of human development and disease. Journal of Molecular Medicine (Berlin, Germany). PMID 32857169 DOI: 10.1007/S00109-020-01969-W  0.378
2020 Frum T, Ralston A. Culture conditions antagonize lineage-promoting signaling in the mouse blastocyst. Reproduction (Cambridge, England). 160: V5-V7. PMID 32484160 DOI: 10.1530/Rep-20-0107  0.696
2019 Frum T, Watts JL, Ralston A. TEAD4/YAP1/WWTR1 prevent the premature onset of pluripotency prior to the 16-cell stage. Development (Cambridge, England). PMID 31444221 DOI: 10.1242/Dev.179861  0.732
2019 Frum T, Ralston A. Visualizing HIPPO Signaling Components in Mouse Early Embryonic Development. Methods in Molecular Biology (Clifton, N.J.). 1893: 335-352. PMID 30565145 DOI: 10.1007/978-1-4939-8910-2_25  0.743
2019 Daigneault B, Vilarino M, Rajput S, Frum T, Smith G, Ross P. 79 CRISPR gene editing in bovine zygotes — mutation confirmation by integration of protein expression and DNA sequencing analyses Reproduction, Fertility and Development. 31: 165. DOI: 10.1071/Rdv31N1Ab79  0.382
2018 Frum T, Murphy TM, Ralston A. HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo. Elife. 7. PMID 30526858 DOI: 10.7554/Elife.42298  0.771
2018 Daigneault BW, Vilarino M, Rajput SK, Frum T, Smith GW, Ross PJ. CRISPR editing validation, immunostaining and DNA sequencing of individual fixed bovine embryos. Biotechniques. 65: 281-283. PMID 30394131 DOI: 10.2144/Btn-2018-0051  0.441
2018 Frum T, Ralston A. AttrActin' Attention to Early Mouse Development. Cell. 173: 544-545. PMID 29677506 DOI: 10.1016/J.Cell.2018.03.078  0.642
2018 Frum T, Murphy TM, Ralston A. Author response: HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo Elife. DOI: 10.7554/Elife.42298.020  0.697
2015 Frum T, Ralston A. Cell signaling and transcription factors regulating cell fate during formation of the mouse blastocyst. Trends in Genetics : Tig. 31: 402-10. PMID 25999217 DOI: 10.1016/J.Tig.2015.04.002  0.777
2014 Wicklow E, Blij S, Frum T, Hirate Y, Lang RA, Sasaki H, Ralston A. HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. Plos Genetics. 10: e1004618. PMID 25340657 DOI: 10.1371/Journal.Pgen.1004618  0.658
2013 Frum T, Halbisen MA, Wang C, Amiri H, Robson P, Ralston A. Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocyst. Developmental Cell. 25: 610-22. PMID 23747191 DOI: 10.1016/J.Devcel.2013.05.004  0.775
2012 Blij S, Frum T, Akyol A, Fearon E, Ralston A. Maternal Cdx2 is dispensable for mouse development. Development (Cambridge, England). 139: 3969-72. PMID 22992952 DOI: 10.1242/Dev.086025  0.64
2012 Thurman RE, Rynes E, Humbert R, Vierstra J, Maurano MT, Haugen E, Sheffield NC, Stergachis AB, Wang H, Vernot B, Garg K, John S, Sandstrom R, Bates D, Boatman L, ... ... Frum T, et al. The accessible chromatin landscape of the human genome. Nature. 489: 75-82. PMID 22955617 DOI: 10.1038/Nature11232  0.413
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