| Year |
Citation |
Score |
| 2023 |
O'Leary KA, Bates AM, Jin WJ, Burkel BM, Sriramaneni RN, Emma SE, Nystuen EJ, Sumiec EG, Ponik SM, Morris ZS, Schuler LA. Estrogen receptor blockade and radiation therapy cooperate to enhance the response of immunologically cold ER+ breast cancer to immunotherapy. Breast Cancer Research : Bcr. 25: 68. PMID 37312163 DOI: 10.1186/s13058-023-01671-y |
0.319 |
|
| 2022 |
Schuler LA, O'Leary KA. Prolactin: The Third Hormone in Breast Cancer. Frontiers in Endocrinology. 13: 910978. PMID 35784527 DOI: 10.3389/fendo.2022.910978 |
0.4 |
|
| 2021 |
Schuler LA, Murdoch FE. Endogenous and Therapeutic Estrogens: Maestro Conductors of the Microenvironment of ER+ Breast Cancers. Cancers. 13. PMID 34359625 DOI: 10.3390/cancers13153725 |
0.405 |
|
| 2021 |
O'Leary KA, Rugowski DE, Shea MP, Sullivan R, Moser AR, Schuler LA. Prolactin synergizes with canonical Wnt signals to drive development of ER+ mammary tumors via activation of the Notch pathway. Cancer Letters. PMID 33472091 DOI: 10.1016/j.canlet.2021.01.012 |
0.367 |
|
| 2020 |
Morgan MM, Schuler LA, Ciciliano JC, Johnson BP, Alarid ET, Beebe DJ. Modeling chemical effects on breast cancer: the importance of the microenvironment in vitro. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 32118264 DOI: 10.1093/Intbio/Zyaa002 |
0.439 |
|
| 2020 |
Bates AM, O'Leary KA, Emma S, Nystuen E, Sumiec EG, Schuler LA, Morris ZS. Abstract 2255: Enhancing immunogenicity in immunologically cold ER+ breast cancer using estrogen receptor blockade and radiation therapy Immunology. DOI: 10.1158/1538-7445.Am2020-2255 |
0.44 |
|
| 2019 |
Jallow F, O'Leary KA, Rugowski DE, Guerrero JF, Ponik SM, Schuler LA. Dynamic interactions between the extracellular matrix and estrogen activity in progression of ER+ breast cancer. Oncogene. PMID 31406251 DOI: 10.1038/S41388-019-0941-0 |
0.506 |
|
| 2019 |
Campbell KM, O'Leary KA, Rugowski DE, Mulligan WA, Barnell EK, Skidmore ZL, Krysiak K, Griffith M, Schuler LA, Griffith OL. A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation. Cell Reports. 28: 1526-1537.e4. PMID 31390566 DOI: 10.1016/J.Celrep.2019.06.098 |
0.401 |
|
| 2018 |
Shea MP, O'Leary KA, Wegner KA, Vezina CM, Schuler LA. High collagen density augments mTOR-dependent cancer stem cells in ERα+ mammary carcinomas, and increases mTOR-independent lung metastases. Cancer Letters. PMID 29935374 DOI: 10.1016/J.Canlet.2018.06.025 |
0.451 |
|
| 2018 |
Jallow F, Brockman JL, Helzer KT, Rugowski DE, Goffin V, Alarid ET, Schuler LA. 17-Estradiol and ICI182,780 Differentially Regulate STAT5 Isoforms in Female Mammary Epithelium, With Distinct Outcomes. Journal of the Endocrine Society. 2: 293-309. PMID 29594259 DOI: 10.1210/Js.2017-00399 |
0.49 |
|
| 2018 |
Shea MP, O'Leary KA, Fakhraldeen SA, Goffin V, Friedl A, Wisinski KB, Alexander CM, Schuler LA. Anti-estrogen therapy increases plasticity and cancer stemness of prolactin-induced ERα+ mammary carcinomas. Cancer Research. PMID 29363543 DOI: 10.1158/0008-5472.Can-17-0985 |
0.492 |
|
| 2018 |
O'Leary KA, Campbell KM, Rugowski DE, Krysiak K, Mulligan WA, Griffith M, Griffith OL, Schuler LA. Abstract 5104: Prolactin-induced mammary tumors: A preclinical model of luminal B breast cancer which exhibits mutations in the RAS pathway Cancer Research. 78: 5104-5104. DOI: 10.1158/1538-7445.Am2018-5104 |
0.456 |
|
| 2017 |
O'Leary KA, Shea MP, Salituro S, Blohm CE, Schuler LA. Prolactin Alters the Mammary Epithelial Hierarchy, Increasing Progenitors and Facilitating Ovarian Steroid Action. Stem Cell Reports. PMID 28919264 DOI: 10.1016/J.Stemcr.2017.08.011 |
0.514 |
|
| 2017 |
Barcus CE, O'Leary KA, Brockman JL, Rugowski DE, Liu Y, Garcia N, Yu M, Keely PJ, Eliceiri KW, Schuler LA. Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells. Breast Cancer Research : Bcr. 19: 9. PMID 28103936 DOI: 10.1186/S13058-017-0801-1 |
0.537 |
|
| 2016 |
Barcus CE, Keely PJ, Eliceiri KW, Schuler LA. Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cells. Oncotarget. PMID 27344177 DOI: 10.18632/Oncotarget.10137 |
0.511 |
|
| 2016 |
Morgan MM, Johnson BP, Livingston MK, Schuler LA, Alarid ET, Sung KE, Beebe DJ. Personalized in vitro cancer models to predict therapeutic response: Challenges and a framework for improvement. Pharmacology & Therapeutics. PMID 27218886 DOI: 10.1016/J.Pharmthera.2016.05.007 |
0.3 |
|
| 2015 |
Barcus CE, Holt EC, Keely PJ, Eliceiri KW, Schuler LA. Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells. Plos One. 10: e0116891. PMID 25607819 DOI: 10.1371/Journal.Pone.0116891 |
0.521 |
|
| 2015 |
O'Leary KA, Shea MP, Schuler LA. Modeling prolactin actions in breast cancer in vivo: insights from the NRL-PRL mouse. Advances in Experimental Medicine and Biology. 846: 201-20. PMID 25472540 DOI: 10.1007/978-3-319-12114-7_9 |
0.487 |
|
| 2015 |
Barcus CE, Holt EC, Keely PJ, Eliceiri KW, Schuler LA. High density/ stiff collagen matrices enhance E2 and PRL induced cell growth, and inhibit apoptosis in T47D cells. Plos One. DOI: 10.1371/Journal.Pone.0116891.G004 |
0.326 |
|
| 2015 |
Barcus CE, Holt EC, Keely PJ, Eliceiri KW, Schuler LA. Matrix density alters E2-induced changes in transcripts in MCF-7 and T47D cells in a cell-context dependent manner. Plos One. DOI: 10.1371/Journal.Pone.0116891.G002 |
0.301 |
|
| 2014 |
Liu Y, Johnson BP, Shen AL, Wallisser JA, Krentz KJ, Moran SM, Sullivan R, Glover E, Parlow AF, Drinkwater NR, Schuler LA, Bradfield CA. Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 14295-300. PMID 25225411 DOI: 10.1073/Pnas.1209249111 |
0.311 |
|
| 2014 |
O'Leary KA, Rugowski DE, Sullivan R, Schuler LA. Prolactin cooperates with loss of p53 to promote claudin-low mammary carcinomas. Oncogene. 33: 3075-82. PMID 23873024 DOI: 10.1038/Onc.2013.278 |
0.472 |
|
| 2013 |
O'Leary KA, Jallow F, Rugowski DE, Sullivan R, Sinkevicius KW, Greene GL, Schuler LA. Prolactin activates ERα in the absence of ligand in female mammary development and carcinogenesis in vivo. Endocrinology. 154: 4483-92. PMID 24064365 DOI: 10.1210/En.2013-1533 |
0.498 |
|
| 2013 |
Barcus CE, Keely PJ, Eliceiri KW, Schuler LA. Stiff collagen matrices increase tumorigenic prolactin signaling in breast cancer cells. The Journal of Biological Chemistry. 288: 12722-32. PMID 23530035 DOI: 10.1074/Jbc.M112.447631 |
0.515 |
|
| 2013 |
Shea MP, O'Leary KA, Schuler LA. Abstract B006: Tumor cell heterogeneity of prolactin-induced ERα+ mammary carcinomas Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-B006 |
0.458 |
|
| 2012 |
Asher JM, O'Leary KA, Rugowski DE, Arendt LM, Schuler LA. Prolactin promotes mammary pathogenesis independently from cyclin D1. The American Journal of Pathology. 181: 294-302. PMID 22658484 DOI: 10.1016/J.Ajpath.2012.03.041 |
0.685 |
|
| 2012 |
O'Leary K, Sullivan R, Rugowski D, Schuler L. Abstract P2-04-04: Prolactin cooperates with loss of p53 to promote mammary tumorigenesis. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P2-04-04 |
0.363 |
|
| 2011 |
Arendt LM, Rugowski DE, Grafwallner-Huseth TA, Garcia-Barchino MJ, Rui H, Schuler LA. Prolactin-induced mouse mammary carcinomas model estrogen resistant luminal breast cancer. Breast Cancer Research : Bcr. 13: R11. PMID 21276249 DOI: 10.1186/Bcr2819 |
0.721 |
|
| 2011 |
Yu Z, Zhao LX, Jiang CL, Duan Y, Wong L, Carver KC, Schuler LA, Shen B. Bafilomycins produced by an endophytic actinomycete Streptomyces sp. YIM56209. The Journal of Antibiotics. 64: 159-62. PMID 21102599 DOI: 10.1038/Ja.2010.147 |
0.717 |
|
| 2010 |
Schuler LA, Auger AP. Psychosocially influenced cancer: diverse early-life stress experiences and links to breast cancer. Cancer Prevention Research (Philadelphia, Pa.). 3: 1365-70. PMID 21084258 DOI: 10.1158/1940-6207.Capr-10-0238 |
0.372 |
|
| 2010 |
Sakamoto K, Triplett AA, Schuler LA, Wagner KU. Janus kinase 2 is required for the initiation but not maintenance of prolactin-induced mammary cancer. Oncogene. 29: 5359-69. PMID 20639901 DOI: 10.1038/Onc.2010.274 |
0.549 |
|
| 2010 |
Hasen NS, O'Leary KA, Auger AP, Schuler LA. Social isolation reduces mammary development, tumor incidence, and expression of epigenetic regulators in wild-type and p53-heterozygotic mice. Cancer Prevention Research (Philadelphia, Pa.). 3: 620-9. PMID 20424136 DOI: 10.1158/1940-6207.Capr-09-0225 |
0.39 |
|
| 2010 |
Carver KC, Piazza TM, Schuler LA. Prolactin enhances insulin-like growth factor I receptor phosphorylation by decreasing its association with the tyrosine phosphatase SHP-2 in MCF-7 breast cancer cells. The Journal of Biological Chemistry. 285: 8003-12. PMID 20080972 DOI: 10.1074/Jbc.M109.066480 |
0.764 |
|
| 2010 |
O'Leary KA, Moser AR, Schuler LA. Abstract 3273: Prolactin promotes breast lesion progression and alters tumor histotype Cancer Research. 70: 3273-3273. DOI: 10.1158/1538-7445.Am10-3273 |
0.456 |
|
| 2009 |
Arendt LM, Evans LC, Rugowski DE, Garcia-Barchino MJ, Rui H, Schuler LA. Ovarian hormones are not required for PRL-induced mammary tumorigenesis, but estrogen enhances neoplastic processes. The Journal of Endocrinology. 203: 99-110. PMID 19635758 DOI: 10.1677/Joe-09-0221 |
0.758 |
|
| 2009 |
Regehr KJ, Domenech M, Koepsel JT, Carver KC, Ellison-Zelski SJ, Murphy WL, Schuler LA, Alarid ET, Beebe DJ. Biological implications of polydimethylsiloxane-based microfluidic cell culture. Lab On a Chip. 9: 2132-9. PMID 19606288 DOI: 10.1039/B903043C |
0.751 |
|
| 2009 |
Carver KC, Arendt LM, Schuler LA. Complex prolactin crosstalk in breast cancer: new therapeutic implications. Molecular and Cellular Endocrinology. 307: 1-7. PMID 19524120 DOI: 10.1016/J.Mce.2009.03.014 |
0.779 |
|
| 2009 |
Arendt LM, Grafwallner-Huseth TL, Schuler LA. Prolactin-growth factor crosstalk reduces mammary estrogen responsiveness despite elevated ERalpha expression. The American Journal of Pathology. 174: 1065-74. PMID 19179608 DOI: 10.2353/Ajpath.2009.080719 |
0.765 |
|
| 2009 |
Piazza TM, Lu JC, Carver KC, Schuler LA. SRC family kinases accelerate prolactin receptor internalization, modulating trafficking and signaling in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 23: 202-12. PMID 19056863 DOI: 10.1210/Me.2008-0341 |
0.772 |
|
| 2008 |
Carver KC, Schuler LA. Prolactin does not require insulin-like growth factor intermediates but synergizes with insulin-like growth factor I in human breast cancer cells. Molecular Cancer Research : McR. 6: 634-43. PMID 18403642 DOI: 10.1158/1541-7786.Mcr-07-2069 |
0.812 |
|
| 2008 |
Arendt LM, Schuler LA. Transgenic models to study actions of prolactin in mammary neoplasia. Journal of Mammary Gland Biology and Neoplasia. 13: 29-40. PMID 18219562 DOI: 10.1007/S10911-008-9073-9 |
0.745 |
|
| 2008 |
Arendt LM, Schuler LA. Prolactin drives estrogen receptor-alpha-dependent ductal expansion and synergizes with transforming growth factor-alpha to induce mammary tumors in males. The American Journal of Pathology. 172: 194-202. PMID 18156207 DOI: 10.2353/Ajpath.2008.070597 |
0.706 |
|
| 2007 |
Gutzman JH, Rugowski DE, Nikolai SE, Schuler LA. Stat5 activation inhibits prolactin-induced AP-1 activity: distinct prolactin-initiated signals in tumorigenesis dependent on cell context. Oncogene. 26: 6341-8. PMID 17438530 DOI: 10.1038/Sj.Onc.1210454 |
0.789 |
|
| 2007 |
Rose-Hellekant TA, Schroeder MD, Brockman JL, Zhdankin O, Bolstad R, Chen KS, Gould MN, Schuler LA, Sandgren EP. Estrogen receptor-positive mammary tumorigenesis in TGFalpha transgenic mice progresses with progesterone receptor loss. Oncogene. 26: 5238-46. PMID 17334393 DOI: 10.1038/Sj.Onc.1210340 |
0.457 |
|
| 2006 |
Arendt LM, Rose-Hellekant TA, Sandgren EP, Schuler LA. Prolactin potentiates transforming growth factor alpha induction of mammary neoplasia in transgenic mice. The American Journal of Pathology. 168: 1365-74. PMID 16565509 DOI: 10.2353/Ajpath.2006.050861 |
0.719 |
|
| 2005 |
Lu JC, Piazza TM, Schuler LA. Proteasomes mediate prolactin-induced receptor down-regulation and fragment generation in breast cancer cells. The Journal of Biological Chemistry. 280: 33909-16. PMID 16103113 DOI: 10.1074/Jbc.M508118200 |
0.812 |
|
| 2005 |
Brockman JL, Schuler LA. Prolactin signals via Stat5 and Oct-1 to the proximal cyclin D1 promoter. Molecular and Cellular Endocrinology. 239: 45-53. PMID 15885880 DOI: 10.1016/J.Mce.2005.04.006 |
0.344 |
|
| 2005 |
Gutzman JH, Nikolai SE, Rugowski DE, Watters JJ, Schuler LA. Prolactin and estrogen enhance the activity of activating protein 1 in breast cancer cells: role of extracellularly regulated kinase 1/2-mediated signals to c-fos. Molecular Endocrinology (Baltimore, Md.). 19: 1765-78. PMID 15746191 DOI: 10.1210/Me.2004-0339 |
0.807 |
|
| 2004 |
Gutzman JH, Rugowski DE, Schroeder MD, Watters JJ, Schuler LA. Multiple kinase cascades mediate prolactin signals to activating protein-1 in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 18: 3064-75. PMID 15319452 DOI: 10.1210/Me.2004-0187 |
0.794 |
|
| 2004 |
Gutzman JH, Miller KK, Schuler LA. Endogenous human prolactin and not exogenous human prolactin induces estrogen receptor α and prolactin receptor expression and increases estrogen responsiveness in breast cancer cells Journal of Steroid Biochemistry and Molecular Biology. 88: 69-77. PMID 15026085 DOI: 10.1016/J.Jsbmb.2003.10.008 |
0.813 |
|
| 2004 |
Karp CM, Pan H, Zhang M, Buckley DJ, Schuler LA, Buckley AR. Identification of HRPAP20: a novel phosphoprotein that enhances growth and survival in hormone-responsive tumor cells. Cancer Research. 64: 1016-25. PMID 14871833 DOI: 10.1158/0008-5472.Can-03-0023 |
0.427 |
|
| 2003 |
Schroeder MD, Brockman JL, Walker AM, Schuler LA. Inhibition of prolactin (PRL)-induced proliferative signals in breast cancer cells by a molecular mimic of phosphorylated PRL, S179D-PRL. Endocrinology. 144: 5300-7. PMID 12970160 DOI: 10.1210/En.2003-0826 |
0.555 |
|
| 2003 |
Rose-Hellekant TA, Arendt LM, Schroeder MD, Gilchrist K, Sandgren EP, Schuler LA. Prolactin induces ERalpha-positive and ERalpha-negative mammary cancer in transgenic mice. Oncogene. 22: 4664-74. PMID 12879011 DOI: 10.1038/Sj.Onc.1206619 |
0.75 |
|
| 2003 |
Clevenger CV, Furth PA, Hankinson SE, Schuler LA. The role of prolactin in mammary carcinoma. Endocrine Reviews. 24: 1-27. PMID 12588805 DOI: 10.1210/Er.2001-0036 |
0.535 |
|
| 2002 |
Lu JC, Scott P, Strous GJ, Schuler LA. Multiple internalization motifs differentially used by prolactin receptor isoforms mediate similar endocytic pathways. Molecular Endocrinology (Baltimore, Md.). 16: 2515-27. PMID 12403840 DOI: 10.1210/Me.2002-0077 |
0.421 |
|
| 2002 |
Brockman JL, Schroeder MD, Schuler LA. PRL activates the cyclin D1 promoter via the Jak2/Stat pathway. Molecular Endocrinology (Baltimore, Md.). 16: 774-84. PMID 11923474 DOI: 10.1210/Mend.16.4.0817 |
0.43 |
|
| 2002 |
Schroeder MD, Symowicz J, Schuler LA. PRL modulates cell cycle regulators in mammary tumor epithelial cells. Molecular Endocrinology (Baltimore, Md.). 16: 45-57. PMID 11773438 DOI: 10.1210/Mend.16.1.0762 |
0.487 |
|
| 2001 |
Schroeder MD, Rose-Hellekant TA, Sandgren EP, Schuler LA. Dysregulation of mammary Stats 1,3 and 5 and PRL receptors by overexpression of TGFα Molecular and Cellular Endocrinology. 175: 173-183. PMID 11325527 DOI: 10.1016/S0303-7207(01)00385-9 |
0.388 |
|
| 2001 |
Merkle CJ, Schuler LA, Schaeffer RC, Gribbon JM, Montgomery DW. Structural and functional effects of high prolactin levels on injured endothelial cells: evidence for an endothelial prolactin receptor. Endocrine. 13: 37-46. PMID 11051045 DOI: 10.1385/Endo:13:1:37 |
0.383 |
|
| 2000 |
Stewart MD, Johnson GA, Gray CA, Burghardt RC, Schuler LA, Joyce MM, Bazer FW, Spencer TE. Prolactin receptor and uterine milk protein expression in the ovine endometrium during the estrous cycle and pregnancy Biology of Reproduction. 62: 1779-1789. PMID 10819783 DOI: 10.1095/Biolreprod62.6.1779 |
0.345 |
|
| 1998 |
Chen H, Schuler LA, Schultz RD. Growth Hormone Receptor And Regulation Of Gene Expression In Fetal Lymphoid Cells Molecular and Cellular Endocrinology. 137: 21-29. PMID 9607725 DOI: 10.1016/S0303-7207(97)00230-X |
0.39 |
|
| 1997 |
Chen H-, Schuler LA, Schultz RD. Growth Hormone and Pit-1 expression in bovine fetal lymphoid cells Domestic Animal Endocrinology. 14: 399-407. PMID 9437576 DOI: 10.1016/S0739-7240(97)00045-3 |
0.358 |
|
| 1997 |
Schuler LA, Nagel RJ, Gao J, Horseman ND, Kessler MA. Prolactin receptor heterogeneity in bovine fetal and maternal tissues Endocrinology. 138: 3187-3194. PMID 9231767 DOI: 10.1210/Endo.138.8.5292 |
0.395 |
|
| 1992 |
Schuler LA, Kessler MA. Bovine placental prolactin-related hormones Trends in Endocrinology and Metabolism. 3: 334-338. PMID 18407119 DOI: 10.1016/1043-2760(92)90112-E |
0.397 |
|
| 1992 |
Scott P, Kessler MA, Schuler LA. Molecular cloning of the bovine prolactin receptor and distribution of prolactin and growth hormone receptor transcripts in fetal and utero-placental tissues. Molecular and Cellular Endocrinology. 89: 47-58. PMID 1338725 DOI: 10.1016/0303-7207(92)90210-W |
0.364 |
|
| 1992 |
Carnes M, Brownfield M, Lent SJ, Nichols K, Schuler L. Pulsatile ACTH and cortisol in goats: effects of insulin-induced hypoglycemia and dexamethasone. Neuroendocrinology. 55: 97-104. PMID 1319009 DOI: 10.1159/000126102 |
0.301 |
|
| 1991 |
Schuler LA, Kessler MA, Tanaka M, Nakashima K. Nomenclature Clarification for the Bovine Placental Prolactin-Related Hormones Endocrinology. 129: 2057-2057. PMID 1915086 DOI: 10.1210/Endo-129-4-2057 |
0.35 |
|
| 1991 |
Kessler MA, Duello TM, Schuler LA. Expression of prolactin-related hormones in the early bovine conceptus, and potential for paracrine effect on the endometrium. Endocrinology. 129: 1885-1895. PMID 1915073 DOI: 10.1210/Endo-129-4-1885 |
0.335 |
|
| 1990 |
Zieler CG, Kessler MA, Schuler LA. Characterization of a novel prolactin-related protein from bovine fetal placenta. Endocrinology. 126: 2377-2382. PMID 1691697 DOI: 10.1210/Endo-126-5-2377 |
0.301 |
|
| 1989 |
Kessler MA, Milosavljevic M, Zieler CG, Schuler LA. A subfamily of bovine prolactin-related transcripts distinct from placental lactogen in the fetal placenta. Biochemistry. 28: 5154-61. PMID 2765528 DOI: 10.1021/Bi00438A036 |
0.331 |
|
| 1989 |
Milosavljevic M, Duello TM, Schuler LA. In situ localization of two prolactin-related messenger ribonucleic acids to binucleate cells of bovine placentomes. Endocrinology. 125: 883-9. PMID 2752982 DOI: 10.1210/Endo-125-2-883 |
0.314 |
|
| 1988 |
Schuler LA, Shimomura K, Kessler MA, Zieler CG, Bremel RD. Bovine placental lactogen: molecular cloning and protein structure Biochemistry. 27: 8443-8448. PMID 3242594 DOI: 10.1021/Bi00422A022 |
0.327 |
|
| 1987 |
Schuler LA, Hurley WL. Molecular cloning of a prolactin-related mRNA expressed in bovine placenta. Proceedings of the National Academy of Sciences of the United States of America. 84: 5650-5654. PMID 3475696 DOI: 10.1073/Pnas.84.16.5650 |
0.339 |
|
| Show low-probability matches. |