| Year |
Citation |
Score |
| 2019 |
Zhao Y, Zhao X, Chen V, Feng Y, Wang L, Croniger C, Conlon RA, Markowitz S, Fearon E, Puchowicz M, Brunengraber H, Hao Y, Wang Z. Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo. Scientific Reports. 9: 19180. PMID 31844152 DOI: 10.1038/S41598-019-55718-2 |
0.365 |
|
| 2019 |
Hung S, Saiakhova A, Faber ZJ, Bartels CF, Neu D, Bayles I, Ojo E, Hong ES, Pontius WD, Morton AR, Liu R, Kalady MF, Wald DN, Markowitz S, Scacheri PC. Mismatch repair-signature mutations activate gene enhancers across human colorectal cancer epigenomes. Elife. 8. PMID 30759065 DOI: 10.7554/Elife.40760 |
0.403 |
|
| 2018 |
Forrest ME, Saiakhova A, Beard L, Buchner DA, Scacheri PC, LaFramboise T, Markowitz S, Khalil AM. Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis. Scientific Reports. 8: 7324. PMID 29743621 DOI: 10.1038/S41598-018-25530-5 |
0.306 |
|
| 2018 |
Hung S, Saiakhova A, Faber ZJ, Bartels CF, Neu D, Bayles I, Ojo E, Hong ES, Pontius WD, Morton AR, Liu R, Kalady MF, Wald DN, Markowitz S, Scacheri PC. Author response: Mismatch repair-signature mutations activate gene enhancers across human colorectal cancer epigenomes Elife. DOI: 10.7554/Elife.40760.032 |
0.401 |
|
| 2016 |
Venkitachalam S, Revoredo L, Varadan V, Fecteau RE, Ravi L, Lutterbaugh J, Markowitz SD, Willis JE, Gerken TA, Guda K. Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer. Scientific Reports. 6: 23642. PMID 27004849 DOI: 10.1038/Srep23642 |
0.335 |
|
| 2016 |
Fink SP, Myeroff L, Kariv R, Platzer P, Xin B, Mikkola D, Lawrence E, Morris N, Nosrati A, Willson J, Willis J, Veigl M, Barnholtz-Sloan J, Wang Z, Markowitz S. Abstract 3126: CEMIP, a secreted protein highly induced in colon cancer and associated with poor patient survival Cancer Research. 76: 3126-3126. DOI: 10.1158/1538-7445.Am2016-3126 |
0.419 |
|
| 2016 |
Merry CR, Forrest ME, Markowitz S, Khalil AM. Abstract 1937: Dysregulation of lincRNAs is a major driver of aberrant epigenomes during tumorigenesis Cancer Research. 76: 1937-1937. DOI: 10.1158/1538-7445.Am2016-1937 |
0.405 |
|
| 2015 |
Merry CR, Forrest ME, Sabers JN, Beard L, Gao XH, Hatzoglou M, Jackson MW, Wang Z, Markowitz SD, Khalil AM. DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer. Human Molecular Genetics. 24: 6240-53. PMID 26307088 DOI: 10.1093/Hmg/Ddv343 |
0.323 |
|
| 2015 |
Venkitachalam S, Revoredo L, Ravi L, Lutterbaugh J, Markowitz S, Gerken T, Guda K. Abstract 1113: Novel recurrent glycosylation-associated gene mutations in colon cancer Cancer Research. 75: 1113-1113. DOI: 10.1158/1538-7445.Am2015-1113 |
0.451 |
|
| 2014 |
Corradin O, Saiakhova A, Akhtar-Zaidi B, Myeroff L, Willis J, Cowper-Sal lari R, Lupien M, Markowitz S, Scacheri PC. Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits. Genome Research. 24: 1-13. PMID 24196873 DOI: 10.1101/Gr.164079.113 |
0.304 |
|
| 2014 |
Fink SP, Yamauchi M, Nishihara R, Jung S, Kuchiba A, Wu K, Cho E, Giovannucci E, Fuchs C, Ogino S, Markowitz S, Chan AT. 777 Aspirin Use and the Risk of Colorectal Cancer Is Modified According to Colonic 15-Prostaglandin Dehydrogenase Expression Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)60465-0 |
0.353 |
|
| 2013 |
Luo Y, Kaz AM, Kanngurn S, Welsch P, Morris SM, Wang J, Lutterbaugh JD, Markowitz SD, Grady WM. NTRK3 is a potential tumor suppressor gene commonly inactivated by epigenetic mechanisms in colorectal cancer. Plos Genetics. 9: e1003552. PMID 23874207 DOI: 10.1371/journal.pgen.1003552 |
0.331 |
|
| 2013 |
Hao Y, Wang C, Zheng W, Sedwick D, Markowitz S, Ewing R, Liu L, Wang Z. Abstract 5155: Gain of direct interaction with IRS1 by the helical domain mutations of p110 alpha is crucial for their oncogenic functions. Cancer Research. 73: 5155-5155. DOI: 10.1158/1538-7445.Am2013-5155 |
0.348 |
|
| 2012 |
Akhtar-Zaidi B, Cowper-Sal-lari R, Corradin O, Saiakhova A, Bartels CF, Balasubramanian D, Myeroff L, Lutterbaugh J, Jarrar A, Kalady MF, Willis J, Moore JH, Tesar PJ, Laframboise T, Markowitz S, et al. Epigenomic enhancer profiling defines a signature of colon cancer. Science (New York, N.Y.). 336: 736-9. PMID 22499810 DOI: 10.1126/Science.1217277 |
0.407 |
|
| 2012 |
Bulgar AD, Weeks LD, Miao Y, Yang S, Xu Y, Guo C, Markowitz S, Oleinick N, Gerson SL, Liu L. Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair. Cell Death & Disease. 3: e252. PMID 22237209 DOI: 10.1038/Cddis.2011.135 |
0.315 |
|
| 2012 |
Dazard JE, Sunil Rao J, Markowitz S. Local sparse bump hunting reveals molecular heterogeneity of colon tumors Statistics in Medicine. 31: 1203-1220. PMID 22052459 DOI: 10.1002/Sim.4389 |
0.354 |
|
| 2011 |
Bulgar A, Weeks LD, Miao Y, Yang S, Xu Y, Guo C, Markowitz S, Gerson SL, Liu L. Abstract A104: Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: Overriding the limit with methoxyamine (TRC102) to inhibit base excision repair. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-A104 |
0.333 |
|
| 2010 |
Sun X, Elston R, Barnholtz-Sloan J, Falk GW, Grady WM, Kinnard MF, Mittal SK, Willis J, Markowitz S, Brock WE, Chak A. 16 A Segregation Analysis of Barrett's Esophagus and Associated Adenocarcinomas Gastroenterology. 138: S-2-S-3. DOI: 10.1016/S0016-5085(10)60010-8 |
0.305 |
|
| 2009 |
Guda K, Moinova H, He J, Jamison O, Ravi L, Natale L, Lutterbaugh J, Lawrence E, Lewis S, Willson JKV, Lowe JB, Wiesner GL, Parmigiani G, Barnholtz-Sloan J, Dawson DW, ... ... Markowitz SD, et al. Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers Proceedings of the National Academy of Sciences of the United States of America. 106: 12921-12925. PMID 19617566 DOI: 10.1073/Pnas.0901454106 |
0.318 |
|
| 2009 |
Nibbe RK, Markowitz S, Myeroff L, Ewing R, Chance MR. Discovery and scoring of protein interaction subnetworks discriminative of late stage human colon cancer. Molecular & Cellular Proteomics : McP. 8: 827-45. PMID 19098285 DOI: 10.1074/Mcp.M800428-Mcp200 |
0.334 |
|
| 2008 |
Itzkowitz S, Brand R, Jandorf L, Durkee K, Millholland J, Rabeneck L, Schroy PC, Sontag S, Johnson D, Markowitz S, Paszat L, Berger BM. A simplified, noninvasive stool DNA test for colorectal cancer detection. The American Journal of Gastroenterology. 103: 2862-70. PMID 18759824 DOI: 10.1111/J.1572-0241.2008.02088.X |
0.344 |
|
| 2008 |
Biswas S, Trobridge P, Romero-Gallo J, Billheimer D, Myeroff LL, Willson JK, Markowitz SD, Grady WM. Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming growth factor beta resistant cells. Genes, Chromosomes & Cancer. 47: 95-106. PMID 17985359 DOI: 10.1002/gcc.20511 |
0.324 |
|
| 2008 |
Itzkowitz SH, Brand R, Jandorf L, Rabeneck L, Schroy PC, Sontag SJ, Johnson DA, Markowitz S, Millholland JM, Durkee KH, Paszat L, Berger BM. T1098 Improved Non-Invasive Stool DNA (SDNA) Test to Screen for Colorectal Cancer (CRC): Validation of High Sensitivity and Specificity Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)62259-3 |
0.317 |
|
| 2007 |
Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, ... ... Markowitz SD, et al. The genomic landscapes of human breast and colorectal cancers. Science (New York, N.Y.). 318: 1108-13. PMID 17932254 DOI: 10.1126/science.1145720 |
0.309 |
|
| 2007 |
Itzkowitz SH, Jandorf L, Brand R, Rabeneck L, Schroy PC, Sontag S, Johnson D, Skoletsky J, Durkee K, Markowitz S, Shuber A. Improved fecal DNA test for colorectal cancer screening. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 5: 111-7. PMID 17161655 DOI: 10.1016/J.Cgh.2006.10.006 |
0.363 |
|
| 2006 |
Grady WM, Willis JE, Trobridge P, Romero-Gallo J, Munoz N, Olechnowicz J, Ferguson K, Gautam S, Markowitz SD. Proliferation and Cdk4 expression in microsatellite unstable colon cancers with TGFBR2 mutations International Journal of Cancer. 118: 600-608. PMID 16108056 DOI: 10.1002/ijc.21399 |
0.309 |
|
| 2005 |
Xin B, Platzer P, Fink SP, Reese L, Nosrati A, Willson JK, Wilson K, Markowitz S. Colon cancer secreted protein-2 (CCSP-2), a novel candidate serological marker of colon neoplasia. Oncogene. 24: 724-31. PMID 15580307 DOI: 10.1038/Sj.Onc.1208134 |
0.398 |
|
| 2004 |
Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, ... ... Markowitz S, et al. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science (New York, N.Y.). 304: 1164-6. PMID 15155950 DOI: 10.1126/Science.1096096 |
0.409 |
|
| 2004 |
Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S, Yan H, Gazdar A, Powell SM, Riggins GJ, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE. High frequency of mutations of the PIK3CA gene in human cancers. Science (New York, N.Y.). 304: 554. PMID 15016963 DOI: 10.1126/Science.1096502 |
0.337 |
|
| 2004 |
Ionov Y, Nowak N, Perucho M, Markowitz S, Cowell JK. Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability. Oncogene. 23: 639-45. PMID 14737099 DOI: 10.1038/Sj.Onc.1207178 |
0.386 |
|
| 2003 |
Li H, Myeroff L, Smiraglia D, Romero MF, Pretlow TP, Kasturi L, Lutterbaugh J, Rerko RM, Casey G, Issa JP, Willis J, Willson JK, Plass C, Markowitz SD. SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers. Proceedings of the National Academy of Sciences of the United States of America. 100: 8412-7. PMID 12829793 DOI: 10.1073/Pnas.1430846100 |
0.328 |
|
| 2003 |
Fink SP, Mikkola D, Willson JKV, Markowitz S. TGF- β -induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines Oncogene. 22: 1317-1323. PMID 12618756 DOI: 10.1038/Sj.Onc.1206128 |
0.308 |
|
| 2003 |
Hempen PM, Zhang L, Bansal RK, Iacobuzio-Donahue CA, Murphy KM, Maitra A, Vogelstein B, Whitehead RH, Markowitz SD, Willson JK, Yeo CJ, Hruban RH, Kern SE. Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. Cancer Research. 63: 994-9. PMID 12615714 |
0.305 |
|
| 2002 |
Grady WM, Markowitz SD. Genetic and epigenetic alterations in colon cancer. Annual Review of Genomics and Human Genetics. 3: 101-28. PMID 12142355 DOI: 10.1146/annurev.genom.3.022502.103043 |
0.315 |
|
| 2002 |
Moinova HR, Chen WD, Shen L, Smiraglia D, Olechnowicz J, Ravi L, Kasturi L, Myeroff L, Plass C, Parsons R, Minna J, Willson JK, Green SB, Issa JP, Markowitz SD. HLTF gene silencing in human colon cancer. Proceedings of the National Academy of Sciences of the United States of America. 99: 4562-7. PMID 11904375 DOI: 10.1073/Pnas.062459899 |
0.321 |
|
| 2002 |
Wang TL, Rago C, Silliman N, Ptak J, Markowitz S, Willson JK, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. Prevalence of somatic alterations in the colorectal cancer cell genome. Proceedings of the National Academy of Sciences of the United States of America. 99: 3076-80. PMID 11867767 DOI: 10.1073/Pnas.261714699 |
0.322 |
|
| 2002 |
Li H, Myeroff L, Kasturi L, Krumroy L, Schwartz S, Willson JK, Stanbridge E, Casey G, Markowitz S. Chromosomal autonomy of hMLH1 methylation in colon cancer. Oncogene. 21: 1443-9. PMID 11857087 DOI: 10.1038/Sj/Onc/1205247 |
0.338 |
|
| 2000 |
Grady WM, Markowitz S. Genomic instability and colorectal cancer. Current Opinion in Gastroenterology. 16: 62-7. PMID 17024019 DOI: 10.1097/00001574-200001000-00012 |
0.446 |
|
| 2000 |
Grady WM, Willis J, Guilford PJ, Dunbier AK, Toro TT, Lynch H, Wiesner G, Ferguson K, Eng C, Park JG, Kim SJ, Markowitz S. Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer Nature Genetics. 26: 16-17. PMID 10973239 DOI: 10.1038/79120 |
0.397 |
|
| 2000 |
Grady WM, Guilford PJ, Willis J, Lynch H, Ferguson K, Weisner GL, Rajput A, Markowitz S. Inactivation of E-cadherin in stomach cancers arising in the hereditary diffuse gastric cancer syndrome Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)84797-6 |
0.323 |
|
| 2000 |
Grady WM, Markowitz S, Willis J. CPG island methylator phenotype and patients with multiple colorectal cancers Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)82254-4 |
0.371 |
|
| 1998 |
Liu DF, Grady WM, Rajput A, Markowitz S, Willis J. p27KIPI Expression inversely correlates with microsatellite instability and TGF-β receptor type II mutations in sporadic colon cancer Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)82600-0 |
0.345 |
|
| 1995 |
Liu B, Nicolaides NC, Markowitz S, Willson JKV, Parsons RE, Jen J, Papadopolous N, Peltomäki P, de la Chapelle A, Hamilton SR, Kinzler KW, Vogelstein B. Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability Nature Genetics. 9: 48-55. PMID 7704024 DOI: 10.1038/Ng0195-48 |
0.391 |
|
| 1995 |
da Costa LT, Liu B, El-Deiry WS, Hamilton SR, Kinzler KW, Vogelstein B, Markowitz S, Willson JKV, de la Chapelle A, Downey KM, So AG. Polymerase δ variants in RER colorectal tumours Nature Genetics. 9: 10-11. PMID 7704014 DOI: 10.1038/Ng0195-10 |
0.301 |
|
| 1995 |
Papadopoulos N, Nicolaides NC, Liu B, Parsons R, Lengauer C, Palombo F, D'Arrigo A, Markowitz S, Willson JK, Kinzler KW. Mutations of GTBP in genetically unstable cells. Science (New York, N.Y.). 268: 1915-7. PMID 7604266 DOI: 10.1126/Science.7604266 |
0.354 |
|
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