| Year |
Citation |
Score |
| 2023 |
Vickridge E, Faraco CCF, Lo F, Rahimian H, Liu ZY, Tehrani PS, Djerir B, Ramdzan ZM, Leduy L, Maréchal A, Gingras AC, Nepveu A. The function of BCL11B in base excision repair contributes to its dual role as an oncogene and a haplo-insufficient tumor suppressor gene. Nucleic Acids Research. PMID 37956270 DOI: 10.1093/nar/gkad1037 |
0.338 |
|
| 2022 |
Vickridge E, Faraco CCF, Tehrani PS, Ramdzan ZM, Rahimian H, Leduy L, Gingras AC, Nepveu A. The DNA repair function of BCL11A suppresses senescence and promotes continued proliferation of triple-negative breast cancer cells. Nar Cancer. 4: zcac028. PMID 36186110 DOI: 10.1093/narcan/zcac028 |
0.318 |
|
| 2021 |
Ramdzan ZM, Vickridge E, Faraco CCF, Nepveu A. CUT Domain Proteins in DNA Repair and Cancer. Cancers. 13. PMID 34204734 DOI: 10.3390/cancers13122953 |
0.307 |
|
| 2019 |
Aly M, Ramdzan ZM, Nagata Y, Balasubramanian SK, Hosono N, Makishima H, Visconte V, Kuzmanovic T, Adema V, Nazha A, Przychodzen BP, Kerr CM, Sekeres MA, Abazeed ME, Nepveu A, et al. Distinct clinical and biological implications of in myeloid neoplasms. Blood Advances. 3: 2164-2178. PMID 31320321 DOI: 10.1182/Bloodadvances.2018028423 |
0.315 |
|
| 2017 |
Kaur S, Ramdzan ZM, Guiot MC, Li L, Leduy L, Ramotar D, Sabri S, Abdulkarim B, Nepveu A. CUX1 Stimulates APE1 Enzymatic Activity and Increases the Resistance of Glioblastoma Cells to the Mono-Alkylating Agent, Temozolomide. Neuro-Oncology. PMID 29036362 DOI: 10.1093/Neuonc/Nox178 |
0.306 |
|
| 2017 |
Ramdzan ZM, Ginjala V, Pinder JB, Chung D, Donovan CM, Kaur S, Leduy L, Dellaire G, Ganesan S, Nepveu A. The DNA repair function of CUX1 contributes to radioresistance. Oncotarget. PMID 28147323 DOI: 10.18632/Oncotarget.14875 |
0.404 |
|
| 2016 |
Kaur S, Coulombe Y, Ramdzan ZM, Leduy L, Masson JY, Nepveu A. SATB1 Functions as an Accessory Factor in Base Excision Repair. The Journal of Biological Chemistry. PMID 27590341 DOI: 10.1074/Jbc.M116.735696 |
0.412 |
|
| 2015 |
Pal R, Ramdzan ZM, Kaur S, Duquette PM, Marcotte R, Leduy L, Davoudi S, Lamarche-Vane N, Iulianella A, Nepveu A. CUX2 Protein Functions as an Accessory Factor in the Repair of Oxidative DNA Damage. The Journal of Biological Chemistry. 290: 22520-31. PMID 26221032 DOI: 10.1074/Jbc.M115.651042 |
0.35 |
|
| 2014 |
Vadnais C, Shooshtarizadeh P, Rajadurai CV, Lesurf R, Hulea L, Davoudi S, Cadieux C, Hallett M, Park M, Nepveu A. Autocrine Activation of the Wnt/β-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers. Biology Open. 3: 937-46. PMID 25217618 DOI: 10.1242/Bio.20148193 |
0.387 |
|
| 2014 |
Ramdzan ZM, Vadnais C, Pal R, Vandal G, Cadieux C, Leduy L, Davoudi S, Hulea L, Yao L, Karnezis AN, Paquet M, Dankort D, Nepveu A. RAS transformation requires CUX1-dependent repair of oxidative DNA damage. Plos Biology. 12: e1001807. PMID 24618719 DOI: 10.1371/Journal.Pbio.1001807 |
0.417 |
|
| 2013 |
Vadnais C, Awan AA, Harada R, Clermont PL, Leduy L, Bérubé G, Nepveu A. Long-range transcriptional regulation by the p110 CUX1 homeodomain protein on the ENCODE array. Bmc Genomics. 14: 258. PMID 23590133 DOI: 10.1186/1471-2164-14-258 |
0.459 |
|
| 2013 |
Hosono N, Ramdzan ZM, Pal R, Makishima H, Przychodzen BP, Sekeres MA, Yoshida K, Shiraishi Y, Miyano S, Ogawa S, Nepveu A, Maciejewski JP. Somatic Mutations and Loss-Of-Heterozygosity Impair The DNA Repair Functions Of CUX1 in Myelodysplastic Syndromes (MDS) Blood. 122: 1246-1246. DOI: 10.1182/Blood.V122.21.1246.1246 |
0.351 |
|
| 2012 |
Vadnais C, Davoudi S, Afshin M, Harada R, Dudley R, Clermont PL, Drobetsky E, Nepveu A. CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage. Nucleic Acids Research. 40: 4483-95. PMID 22319212 DOI: 10.1093/Nar/Gks041 |
0.316 |
|
| 2012 |
Hulea L, Nepveu A. CUX1 transcription factors: from biochemical activities and cell-based assays to mouse models and human diseases. Gene. 497: 18-26. PMID 22306263 DOI: 10.1016/j.gene.2012.01.039 |
0.375 |
|
| 2012 |
Harada R, Nepveu A. Chromatin affinity purification. Methods in Molecular Biology (Clifton, N.J.). 809: 237-53. PMID 22113280 DOI: 10.1007/978-1-61779-376-9_16 |
0.428 |
|
| 2011 |
Sansregret L, Vadnais C, Livingstone J, Kwiatkowski N, Awan A, Cadieux C, Leduy L, Hallett MT, Nepveu A. Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure. Proceedings of the National Academy of Sciences of the United States of America. 108: 1949-54. PMID 21245318 DOI: 10.1073/Pnas.1008403108 |
0.393 |
|
| 2010 |
Sansregret L, Gallo D, Santaguida M, Leduy L, Harada R, Nepveu A. Hyperphosphorylation by cyclin B/CDK1 in mitosis resets CUX1 DNA binding clock at each cell cycle. The Journal of Biological Chemistry. 285: 32834-43. PMID 20729212 DOI: 10.1074/Jbc.M110.156406 |
0.559 |
|
| 2010 |
Kedinger V, Nepveu A. The roles of CUX1 homeodomain proteins in the establishment of a transcriptional program required for cell migration and invasion. Cell Adhesion & Migration. 4: 348-52. PMID 20224295 DOI: 10.4161/Cam.4.3.11407 |
0.524 |
|
| 2010 |
Ceru S, Konjar S, Maher K, Repnik U, Krizaj I, Bencina M, Renko M, Nepveu A, Zerovnik E, Turk B, Kopitar-Jerala N. Stefin B interacts with histones and cathepsin L in the nucleus. The Journal of Biological Chemistry. 285: 10078-86. PMID 20075068 DOI: 10.1074/Jbc.M109.034793 |
0.411 |
|
| 2010 |
Ramzdan Z, Cadieux C, Drossos M, Nepveu A. Abstract P5-05-15: Transgenic Mice Expressing Either p200, p110 or p75 CUX1 Isoform Develop Mammary Tumors of Various Histological Types Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P5-05-15 |
0.451 |
|
| 2009 |
Cadieux C, Kedinger V, Yao L, Vadnais C, Drossos M, Paquet M, Nepveu A. Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types. Cancer Research. 69: 7188-97. PMID 19738070 DOI: 10.1158/0008-5472.Can-08-4899 |
0.405 |
|
| 2009 |
Siam R, Harada R, Cadieux C, Battat R, Vadnais C, Nepveu A. Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice. Molecular Cancer. 8: 60. PMID 19656388 DOI: 10.1186/1476-4598-8-60 |
0.446 |
|
| 2009 |
Kedinger V, Sansregret L, Harada R, Vadnais C, Cadieux C, Fathers K, Park M, Nepveu A. p110 CUX1 homeodomain protein stimulates cell migration and invasion in part through a regulatory cascade culminating in the repression of E-cadherin and occludin. The Journal of Biological Chemistry. 284: 27701-11. PMID 19635798 DOI: 10.1074/Jbc.M109.031849 |
0.511 |
|
| 2009 |
Seguin L, Liot C, Mzali R, Harada R, Siret A, Nepveu A, Bertoglio J. CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. Molecular and Cellular Biology. 29: 570-81. PMID 19015243 DOI: 10.1128/Mcb.01275-08 |
0.514 |
|
| 2009 |
Wilson BJ, Harada R, LeDuy L, Hollenberg MD, Nepveu A. CUX1 transcription factor is a downstream effector of the proteinase-activated receptor 2 (PAR2). The Journal of Biological Chemistry. 284: 36-45. PMID 18952606 DOI: 10.1074/Jbc.M803808200 |
0.535 |
|
| 2009 |
Lu Y, Adegoke OAJ, Nepveu A, Nakayama KI, Bedard N, Cheng D, Peng J, Wing SS. USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1 (Molecular and Cellular Biology (2009) 29, 2, (547-558)) Molecular and Cellular Biology. 29. DOI: 10.1128/Mcb.00437-09 |
0.321 |
|
| 2008 |
Goulet B, Markovic Y, Leduy L, Nepveu A. Proteolytic processing of cut homeobox 1 by neutrophil elastase in the MV4;11 myeloid leukemia cell line. Molecular Cancer Research : McR. 6: 644-53. PMID 18403643 DOI: 10.1158/1541-7786.Mcr-07-0268 |
0.8 |
|
| 2008 |
Cadieux C, Harada R, Paquet M, Côté O, Trudel M, Nepveu A, Bouchard M. Polycystic kidneys caused by sustained expression of Cux1 isoform p75. The Journal of Biological Chemistry. 283: 13817-24. PMID 18356167 DOI: 10.1074/Jbc.M709332200 |
0.362 |
|
| 2008 |
Truscott M, Harada R, Vadnais C, Robert F, Nepveu A. p110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes. Molecular and Cellular Biology. 28: 3127-38. PMID 18347061 DOI: 10.1128/Mcb.02089-07 |
0.521 |
|
| 2008 |
Sansregret L, Nepveu A. The multiple roles of CUX1: insights from mouse models and cell-based assays. Gene. 412: 84-94. PMID 18313863 DOI: 10.1016/J.Gene.2008.01.017 |
0.524 |
|
| 2008 |
Harada R, Vadnais C, Sansregret L, Leduy L, Bérubé G, Robert F, Nepveu A. Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes. Nucleic Acids Research. 36: 189-202. PMID 18003658 DOI: 10.1093/Nar/Gkm970 |
0.49 |
|
| 2007 |
Goulet B, Sansregret L, Leduy L, Bogyo M, Weber E, Chauhan SS, Nepveu A. Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation. Molecular Cancer Research : McR. 5: 899-907. PMID 17855659 DOI: 10.1158/1541-7786.Mcr-07-0160 |
0.79 |
|
| 2007 |
Truscott M, Denault JB, Goulet B, Leduy L, Salvesen GS, Nepveu A. Carboxyl-terminal proteolytic processing of CUX1 by a caspase enables transcriptional activation in proliferating cells. The Journal of Biological Chemistry. 282: 30216-26. PMID 17681953 DOI: 10.1074/Jbc.M702328200 |
0.793 |
|
| 2006 |
Cadieux C, Fournier S, Peterson AC, Bédard C, Bedell BJ, Nepveu A. Transgenic mice expressing the p75 CCAAT-displacement protein/Cut homeobox isoform develop a myeloproliferative disease-like myeloid leukemia. Cancer Research. 66: 9492-501. PMID 17018605 DOI: 10.1158/0008-5472.Can-05-4230 |
0.357 |
|
| 2006 |
Goulet B, Truscott M, Nepveu A. A novel proteolytically processed CDP/Cux isoform of 90 kDa is generated by cathepsin L. Biological Chemistry. 387: 1285-93. PMID 16972798 DOI: 10.1515/Bc.2006.159 |
0.784 |
|
| 2006 |
Sansregret L, Goulet B, Harada R, Wilson B, Leduy L, Bertoglio J, Nepveu A. The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phase. Molecular and Cellular Biology. 26: 2441-55. PMID 16508018 DOI: 10.1128/Mcb.26.6.2441-2455.2006 |
0.792 |
|
| 2005 |
Santaguida M, Nepveu A. Differential regulation of CDP/Cux p110 by cyclin A/Cdk2 and cyclin A/Cdk1. The Journal of Biological Chemistry. 280: 32712-21. PMID 16081423 DOI: 10.1074/Jbc.M505417200 |
0.489 |
|
| 2005 |
Gingras H, Cases O, Krasilnikova M, Bérubé G, Nepveu A. Biochemical characterization of the mammalian Cux2 protein. Gene. 344: 273-85. PMID 15656993 DOI: 10.1016/J.Gene.2004.11.008 |
0.51 |
|
| 2004 |
Truscott M, Raynal L, Wang Y, Bérubé G, Leduy L, Nepveu A. The N-terminal region of the CCAAT displacement protein (CDP)/Cux transcription factor functions as an autoinhibitory domain that modulates DNA binding. The Journal of Biological Chemistry. 279: 49787-94. PMID 15377665 DOI: 10.1074/Jbc.M409484200 |
0.463 |
|
| 2004 |
Goulet B, Nepveu A. Complete and limited proteolysis in cell cycle progression. Cell Cycle (Georgetown, Tex.). 3: 986-9. PMID 15254406 DOI: 10.4161/Cc.3.8.1025 |
0.793 |
|
| 2004 |
Goulet B, Baruch A, Moon NS, Poirier M, Sansregret LL, Erickson A, Bogyo M, Nepveu A. A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor. Molecular Cell. 14: 207-19. PMID 15099520 DOI: 10.1016/S1097-2765(04)00209-6 |
0.755 |
|
| 2003 |
Erturk E, Ostapchuk P, Wells SI, Yang J, Gregg K, Nepveu A, Dudley JP, Hearing P. Binding of CCAAT displacement protein CDP to adenovirus packaging sequences. Journal of Virology. 77: 6255-64. PMID 12743282 DOI: 10.1128/Jvi.77.11.6255-6264.2003 |
0.446 |
|
| 2003 |
Truscott M, Raynal L, Premdas P, Goulet B, Leduy L, Bérubé G, Nepveu A. CDP/Cux stimulates transcription from the DNA polymerase alpha gene promoter. Molecular and Cellular Biology. 23: 3013-28. PMID 12665598 DOI: 10.1128/Mcb.23.8.3013-3028.2003 |
0.787 |
|
| 2002 |
Goulet B, Watson P, Poirier M, Leduy L, Bérubé G, Meterissian S, Jolicoeur P, Nepveu A. Characterization of a tissue-specific CDP/Cux isoform, p75, activated in breast tumor cells. Cancer Research. 62: 6625-33. PMID 12438259 |
0.792 |
|
| 2002 |
Moon NS, Rong Zeng W, Premdas P, Santaguida M, Bérubé G, Nepveu A. Expression of N-terminally truncated isoforms of CDP/CUX is increased in human uterine leiomyomas. International Journal of Cancer. 100: 429-32. PMID 12115525 DOI: 10.1002/Ijc.10510 |
0.751 |
|
| 2001 |
Santaguida M, Ding Q, Bérubé G, Truscott M, Whyte P, Nepveu A. Phosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2). The Journal of Biological Chemistry. 276: 45780-90. PMID 11584018 DOI: 10.1074/jbc.M107978200 |
0.419 |
|
| 2001 |
Moon NS, Premdas P, Truscott M, Leduy L, Bérubé G, Nepveu A. S phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain protein. Molecular and Cellular Biology. 21: 6332-45. PMID 11509674 DOI: 10.1128/Mcb.21.18.6332-6345.2001 |
0.777 |
|
| 2001 |
Nepveu A. Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development. Gene. 270: 1-15. PMID 11403998 DOI: 10.1016/S0378-1119(01)00485-1 |
0.529 |
|
| 2001 |
Nirodi C, Hart J, Dhawan P, Moon NS, Nepveu A, Richmond A. The role of CDP in the negative regulation of CXCL1 gene expression. The Journal of Biological Chemistry. 276: 26122-31. PMID 11371564 DOI: 10.1074/Jbc.M102872200 |
0.745 |
|
| 2000 |
Moon NS, Bérubé G, Nepveu A. CCAAT displacement activity involves CUT repeats 1 and 2, not the CUT homeodomain. The Journal of Biological Chemistry. 275: 31325-34. PMID 10864926 DOI: 10.1074/Jbc.M002912200 |
0.73 |
|
| 2000 |
Martin-Soudant N, Drachman JG, Kaushansky K, Nepveu A. CDP/Cut DNA binding activity is down-modulated in granulocytes, macrophages and erythrocytes but remains elevated in differentiating megakaryocytes Leukemia. 14: 863-873. PMID 10803519 DOI: 10.1038/Sj.Leu.2401764 |
0.41 |
|
| 2000 |
Rong Zeng W, Soucie E, Sung Moon N, Martin-Soudant N, Bérubé G, Leduy L, Nepveu A. Exon/intron structure and alternative transcripts of the CUTL1 gene. Gene. 241: 75-85. PMID 10607901 DOI: 10.1016/S0378-1119(99)00465-5 |
0.372 |
|
| 1999 |
Jackson RJ, Antonia SJ, Wright KL, Moon NS, Nepveu A, Muñoz-Antonia T. Human cut-like repressor protein binds TGFbeta type II receptor gene promoter. Archives of Biochemistry and Biophysics. 371: 290-300. PMID 10545217 DOI: 10.1006/Abbi.1999.1459 |
0.731 |
|
| 1999 |
Wee C, Muise ES, Coquelet O, Ennis M, Wagner J, Lemieux N, Branton PE, Nepveu A, Tremblay ML. Promoter analysis of the murine T-cell protein tyrosine phosphatase gene Gene. 237: 351-360. PMID 10521659 DOI: 10.1016/S0378-1119(99)00332-7 |
0.499 |
|
| 1998 |
Coqueret O, Bérubé G, Nepveu A. The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phase. The Embo Journal. 17: 4680-94. PMID 9707427 DOI: 10.1093/Emboj/17.16.4680 |
0.553 |
|
| 1998 |
Webster MA, Martin-Soudant N, Nepveu A, Cardiff RD, Muller WJ. The induction of uterine leiomyomas and mammary tumors in transgenic mice expressing polyomavirus (PyV) large T (LT) antigen is associated with the ability of PyV LT antigen to form specific complexes with retinoblastoma and CUTL1 family members. Oncogene. 16: 1963-72. PMID 9591780 DOI: 10.1038/Sj.Onc.1201707 |
0.346 |
|
| 1998 |
Coqueret O, Martin N, Bérubé G, Rabbat M, Litchfield DW, Nepveu A. DNA binding by cut homeodomain proteins is down-modulated by casein kinase II. The Journal of Biological Chemistry. 273: 2561-6. PMID 9446557 DOI: 10.1074/jbc.273.5.2561 |
0.36 |
|
| 1997 |
Zeng WR, Scherer SW, Koutsilieris M, Huizenga JJ, Filteau F, Tsui LC, Nepveu A. Loss of heterozygosity and reduced expression of the CUTL1 gene in uterine leiomyomas. Oncogene. 14: 2355-65. PMID 9178912 DOI: 10.1038/Sj.Onc.1201076 |
0.336 |
|
| 1997 |
Higgy NA, Tarnasky HA, Valarché I, Nepveu A, van der Hoorn FA. Cux/CDP homeodomain protein binds to an enhancer in the rat c-mos locus and represses its activity. Biochimica Et Biophysica Acta. 1351: 313-24. PMID 9130595 DOI: 10.1016/S0167-4781(96)00221-7 |
0.447 |
|
| 1996 |
Mailly F, Bérubé G, Harada R, Mao PL, Phillips S, Nepveu A. The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy. Molecular and Cellular Biology. 16: 5346-57. PMID 8816446 DOI: 10.1128/Mcb.16.10.5346 |
0.502 |
|
| 1996 |
Coqueret O, Bérubé G, Nepveu A. DNA binding by cut homeodomain proteins is down-modulated by protein kinase C. The Journal of Biological Chemistry. 271: 24862-8. PMID 8798762 DOI: 10.1074/Jbc.271.40.24862 |
0.459 |
|
| 1995 |
Harada R, Bérubé G, Tamplin OJ, Denis-Larose C, Nepveu A. DNA-binding specificity of the cut repeats from the human cut-like protein. Molecular and Cellular Biology. 15: 129-40. PMID 7799919 DOI: 10.1128/Mcb.15.1.129 |
0.43 |
|
| 1994 |
Dufort D, Nepveu A. The human cut homeodomain protein represses transcription from the c-myc promoter. Molecular and Cellular Biology. 14: 4251-7. PMID 8196661 DOI: 10.1128/Mcb.14.6.4251 |
0.453 |
|
| 1990 |
Miller H, Asselin C, Dufort D, Yang JQ, Gupta K, Marcu KB, Nepveu A. A cis-acting element in the promoter region of the murine c-myc gene is necessary for transcriptional block. Molecular and Cellular Biology. 9: 5340-9. PMID 2685559 DOI: 10.1128/mcb.9.12.5340 |
0.313 |
|
| 1987 |
Wallenburg JC, Nepveu A, Chartrand P. Integration of a vector containing rodent repetitive elements in the rat genome. Nucleic Acids Research. 15: 7849-63. PMID 2823220 DOI: 10.1093/Nar/15.19.7849 |
0.305 |
|
| 1984 |
Wallenburg JC, Nepveu A, Chartrand P. Random and nonrandom integration of a polyomavirus DNA molecule containing highly repetitive cellular sequences. Journal of Virology. 50: 678-83. PMID 6327998 DOI: 10.1128/Jvi.50.3.678-683.1984 |
0.323 |
|
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