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Bangyan L. Stiles - Publications

Affiliations: 
Systems Biology and Disease University of Southern California, Los Angeles, CA, United States 
Area:
Molecular Biology, Genetics, Pathology, Oncology, Cell Biology
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58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Aggarwal R, Peng Z, Zeng N, Silva J, He L, Chen J, Debebe A, Tu T, Alba M, Chen CY, Stiles EX, Hong H, Stiles BL. Chronic Exposure to Palmitic Acid Down-regulates AKT in Beta-Cells through Activation of mTOR. The American Journal of Pathology. PMID 34619135 DOI: 10.1016/j.ajpath.2021.09.008  0.577
2021 Chen J, Debebe A, Zeng N, Kopp J, He L, Sander M, Stiles BL. Transformation of SOX9 cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma. Scientific Reports. 11: 11823. PMID 34083580 DOI: 10.1038/s41598-021-90958-1  0.656
2021 Chen CY, Li Y, Zeng N, He L, Zhang X, Tu T, Tang Q, Alba M, Mir S, Stiles EX, Hong H, Cadenas E, Stolz AA, Li G, Stiles BL. Inhibition of estrogen related receptor α blocks liver steatosis and steatohepatitis and attenuates triglyceride biosynthesis. The American Journal of Pathology. PMID 33894178 DOI: 10.1016/j.ajpath.2021.04.007  0.598
2020 Peng Z, Aggarwal R, Zeng N, He L, Stiles EX, Debebe A, Chen J, Chen CY, Stiles BL. AKT1 regulates endoplasmic reticula stress and mediates adaptive response of pancreatic β-cells. Molecular and Cellular Biology. PMID 32179553 DOI: 10.1128/Mcb.00031-20  0.666
2020 He L, Li Y, Zeng N, Stiles BL. Regulation of basal expression of hepatic PEPCK and G6Pase by AKT2. The Biochemical Journal. PMID 32096546 DOI: 10.1042/Bcj20190570  0.62
2020 Chen C, Li Y, Jia T, He L, Hare AA, Silberstein A, Gallagher J, Martinez TF, Stiles JW, Olenyuk B, Dervan PB, Stiles BL. Repression of the transcriptional activity of ERRα with sequence-specific DNA-binding polyamides Medicinal Chemistry Research. 29: 607-616. DOI: 10.1007/S00044-019-02493-4  0.334
2019 Tu T, Chen J, Chen L, Stiles BL. Dual-Specific Protein and Lipid Phosphatase PTEN and Its Biological Functions. Cold Spring Harbor Perspectives in Medicine. PMID 31548229 DOI: 10.1101/Cshperspect.A036301  0.303
2018 Patil I, Sancheti H, Stiles BL, Cadenas E. Brain metabolic and functional alterations in a liver-specific PTEN knockout mouse model. Plos One. 13: e0204043. PMID 30235271 DOI: 10.1371/Journal.Pone.0204043  0.38
2018 Chen CY, Chen J, He L, Stiles BL. PTEN: Tumor Suppressor and Metabolic Regulator. Frontiers in Endocrinology. 9: 338. PMID 30038596 DOI: 10.3389/Fendo.2018.00338  0.395
2018 Lee J, Liu K, Stiles B, Ou JJ. Mitophagy and Hepatic Cancer Stem Cells. Autophagy. 1-6. PMID 29313421 DOI: 10.1080/15548627.2018.1425058  0.354
2018 Chen J, Chen C, Nguyen C, Chen L, Lee K, Stiles BL. Emerging signals regulating liver tumor initiating cells Liver Research. 2: 73-80. DOI: 10.1016/J.Livres.2018.08.003  0.531
2017 Kopp JL, Dubois CL, Schaeffer DF, Samani A, Taghizadeh F, Cowan RW, Rhim AD, Stiles BL, Valasek M, Sander M. Loss of PTEN and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice. Gastroenterology. PMID 29273451 DOI: 10.1053/J.Gastro.2017.12.007  0.332
2017 Jia C, Medina V, Liu C, He L, Qian D, Taojian T, Okamoto CT, Stiles BL. Crosstalk of LKB1- and PTEN-regulated signals in liver morphogenesis and tumor development. Hepatology Communications. 1: 153-167. PMID 29152604 DOI: 10.1002/hep4.1027  0.371
2017 Debebe A, Medina V, Chen CY, Mahajan IM, Jia C, Fu D, He L, Zeng N, Stiles BW, Chen CL, Wang M, Aggarwal KR, Peng Z, Huang J, Chen J, ... ... Stiles BL, et al. Wnt/β-catenin activation and macrophage induction during liver cancer development following steatosis. Oncogene. PMID 28671671 DOI: 10.1038/Onc.2017.207  0.687
2016 He L, Gubbins J, Peng Z, Medina V, Fei F, Asahina K, Wang J, Kahn M, Rountree CB, Stiles BL. Activation of hepatic stellate cell in Pten null liver injury model. Fibrogenesis & Tissue Repair. 9: 8. PMID 27307790 DOI: 10.1186/S13069-016-0045-1  0.417
2016 Shearn CT, Orlicky DJ, McCullough RL, Jiang H, Maclean KN, Mercer KE, Stiles BL, Saba LM, Ronis MJ, Petersen DR. Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage. Plos One. 11: e0154152. PMID 27124661 DOI: 10.1371/Journal.Pone.0154152  0.348
2015 Bayan JA, Peng Z, Zeng N, He L, Chen J, Stiles BL. Crosstalk Between Activated Myofibroblasts and β Cells in Injured Mouse Pancreas. Pancreas. PMID 26333110 DOI: 10.1097/Mpa.0000000000000431  0.741
2015 Liu Z, Patil IY, Jiang T, Sancheti H, Walsh JP, Stiles BL, Yin F, Cadenas E. High-fat diet induces hepatic insulin resistance and impairment of synaptic plasticity. Plos One. 10: e0128274. PMID 26023930 DOI: 10.1371/Journal.Pone.0128274  0.318
2015 Zeng N, Kassa A, Kopp J, He L, Sander M, Stiles B. Abstract LB-145: Pten deletion in SOX9+ cells synergizes with hepatic injury to drive tumor development in mouse liver Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-145  0.641
2014 Palian BM, Rohira AD, Johnson SA, He L, Zheng N, Dubeau L, Stiles BL, Johnson DL. Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism. Plos Genetics. 10: e1004789. PMID 25502566 DOI: 10.1371/Journal.Pgen.1004789  0.438
2014 Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, ... ... Stiles B, et al. A unified nomenclature and amino acid numbering for human PTEN. Science Signaling. 7: pe15. PMID 24985344 DOI: 10.1126/Scisignal.2005560  0.307
2014 Wu JB, Shao C, Li X, Li Q, Hu P, Shi C, Li Y, Chen YT, Yin F, Liao CP, Stiles BL, Zhau HE, Shih JC, Chung LW. Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis. The Journal of Clinical Investigation. 124: 2891-908. PMID 24865426 DOI: 10.1172/Jci70982  0.373
2014 Shearn CT, Mercer KE, Orlicky DJ, Hennings L, Smathers-McCullough RL, Stiles BL, Ronis MJ, Petersen DR. Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice. Plos One. 9: e96553. PMID 24818992 DOI: 10.1371/Journal.Pone.0096553  0.347
2014 Yang KT, Bayan JA, Zeng N, Aggarwal R, He L, Peng Z, Kassa A, Kim M, Luo Z, Shi Z, Medina V, Boddupally K, Stiles BL. Adult-onset deletion of Pten increases islet mass and beta cell proliferation in mice. Diabetologia. 57: 352-61. PMID 24162585 DOI: 10.1007/S00125-013-3085-8  0.73
2014 Chen WT, Zhu G, Pfaffenbach K, Kanel G, Stiles B, Lee AS. GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN. Oncogene. 33: 4997-5005. PMID 24141775 DOI: 10.1038/Onc.2013.437  0.355
2014 Chen WT, Tseng CC, Pfaffenbach K, Kanel G, Luo B, Stiles BL, Lee AS. Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis. Hepatology (Baltimore, Md.). 59: 947-57. PMID 24027047 DOI: 10.1002/Hep.26711  0.472
2014 Zeng N, Kopp J, He L, Sander M, Stiles B. Abstract 3900: Pten deletion in SOX9+ cells leads to tumor initiating cell expansion and tumor development in mouse liver Cancer Research. 74: 3900-3900. DOI: 10.1158/1538-7445.Am2014-3900  0.664
2014 Li Y, Gallagher J, Olenyuk B, Stiles B, Kassa A. Abstract 2430: Targeting estrogen-related receptor alpha using pyrrole-imidazole polyamide Cancer Research. 74: 2430-2430. DOI: 10.1158/1538-7445.Am2014-2430  0.383
2013 Tsen F, Bhatia A, O'Brien K, Cheng CF, Chen M, Hay N, Stiles B, Woodley DT, Li W. Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo. Molecular and Cellular Biology. 33: 4947-59. PMID 24126057 DOI: 10.1128/Mcb.00559-13  0.461
2013 Li Y, He L, Zeng N, Sahu D, Cadenas E, Shearn C, Li W, Stiles BL. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor α (ERRα). The Journal of Biological Chemistry. 288: 25007-24. PMID 23836899 DOI: 10.1074/Jbc.M113.450353  0.614
2013 Zeng N, Yang KT, Bayan JA, He L, Aggarwal R, Stiles JW, Hou X, Medina V, Abad D, Palian BM, Al-Abdullah I, Kandeel F, Johnson DL, Stiles BL. PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a. Aging Cell. 12: 1000-11. PMID 23826727 DOI: 10.1111/Acel.12132  0.752
2013 Li C, Li Y, He L, Agarwal AR, Zeng N, Cadenas E, Stiles BL. PI3K/AKT signaling regulates bioenergetics in immortalized hepatocytes. Free Radical Biology & Medicine. 60: 29-40. PMID 23376468 DOI: 10.1016/J.Freeradbiomed.2013.01.013  0.595
2013 Chen W, Zhu G, Pfaffenbach K, Kanel G, Stiles B, Lee AS. Abstract C61: GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C61  0.457
2013 Chen W, Tseng C, Pfaffenbach K, Kanel G, Luo B, Stiles BL, Lee AS. Abstract B09: Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-B09  0.474
2013 Kassa AD, Medina VG, Zeng N, He L, Nguyen C, Smbatyan G, Rieger M, Kahn M, Stiles BL. The therapeutic potential of ICG-001 and beta-catenin specific RNAi in liver cancer development Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-4014  0.586
2012 Lin TC, Chen YR, Kensicki E, Li AY, Kong M, Li Y, Mohney RP, Shen HM, Stiles B, Mizushima N, Lin LI, Ann DK. Autophagy: resetting glutamine-dependent metabolism and oxygen consumption. Autophagy. 8: 1477-93. PMID 22906967 DOI: 10.4161/Auto.21228  0.328
2012 Medina VG, Kassa AD, Stiles BL. Abstract 3473: Beta catenin inhibitor ICG-001 attenuates proliferation of hepatic tumor initiating cells in Pten deficient models Cancer Research. 72: 3473-3473. DOI: 10.1158/1538-7445.Am2012-3473  0.577
2011 Zeng N, Li Y, He L, Xu X, Galicia V, Deng C, Stiles BL. Adaptive basal phosphorylation of eIF2α is responsible for resistance to cellular stress-induced cell death in Pten-null hepatocytes. Molecular Cancer Research : McR. 9: 1708-17. PMID 22009178 DOI: 10.1158/1541-7786.Mcr-11-0299  0.604
2011 Stiles BL, Galicia V, He L, Kahn M. Abstract LB-102: Inhibiting the expansion of hepatic cancer stem cells by targeting β-catenin/CBP interaction with ICG-001 in liver Pten deficient mice Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-102  0.556
2010 Zeng N, Bayan JA, He L, Stiles B. The Role of PTEN in β-Cell Growth. The Open Endocrinology Journal. 4: 23-32. PMID 23853672 DOI: 10.2174/1874216501004010023  0.751
2010 Ko KS, Tomasi ML, Iglesias-Ara A, French BA, French SW, Ramani K, Lozano JJ, Oh P, He L, Stiles BL, Li TW, Yang H, Martínez-Chantar ML, Mato JM, Lu SC. Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice. Hepatology (Baltimore, Md.). 52: 2096-108. PMID 20890892 DOI: 10.1002/Hep.23919  0.472
2010 Galicia VA, He L, Dang H, Kanel G, Vendryes C, French BA, Zeng N, Bayan JA, Ding W, Wang KS, French S, Birnbaum MJ, Rountree CB, Stiles BL. Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2. Gastroenterology. 139: 2170-82. PMID 20837017 DOI: 10.1053/J.Gastro.2010.09.002  0.745
2010 Ding W, You H, Dang H, LeBlanc F, Galicia V, Lu SC, Stiles B, Rountree CB. Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion. Hepatology (Baltimore, Md.). 52: 945-53. PMID 20564331 DOI: 10.1002/Hep.23748  0.461
2010 He L, Hou X, Kanel G, Zeng N, Galicia V, Wang Y, Yang J, Wu H, Birnbaum MJ, Stiles BL. The critical role of AKT2 in hepatic steatosis induced by PTEN loss. The American Journal of Pathology. 176: 2302-8. PMID 20348245 DOI: 10.2353/Ajpath.2010.090931  0.657
2010 Galicia VA, Kanel G, He L, Vendryes C, Stiles BL. Abstract 4260: Activation of cancer stem cells in hepaticPtendeficient mice requires liver injury Cancer Research. 70: 4260-4260. DOI: 10.1158/1538-7445.Am10-4260  0.526
2009 Stiles BL. PI-3-K and AKT: Onto the mitochondria. Advanced Drug Delivery Reviews. 61: 1276-82. PMID 19720099 DOI: 10.1016/J.Addr.2009.07.017  0.319
2009 Rountree CB, Ding W, He L, Stiles B. Expansion of CD133-expressing liver cancer stem cells in liver-specific phosphatase and tensin homolog deleted on chromosome 10-deleted mice. Stem Cells (Dayton, Ohio). 27: 290-9. PMID 19008348 DOI: 10.1634/Stemcells.2008-0332  0.361
2009 Stiles BL. Phosphatase and tensin homologue deleted on chromosome 10: extending its PTENtacles. The International Journal of Biochemistry & Cell Biology. 41: 757-61. PMID 18950730 DOI: 10.1016/J.Biocel.2008.09.022  0.419
2008 Valamehr B, Jonas SJ, Polleux J, Qiao R, Guo S, Gschweng EH, Stiles B, Kam K, Luo TJ, Witte ON, Liu X, Dunn B, Wu H. Hydrophobic surfaces for enhanced differentiation of embryonic stem cell-derived embryoid bodies. Proceedings of the National Academy of Sciences of the United States of America. 105: 14459-64. PMID 18791068 DOI: 10.1073/Pnas.0807235105  0.321
2006 Xu X, Kobayashi S, Qiao W, Li C, Xiao C, Radaeva S, Stiles B, Wang RH, Ohara N, Yoshino T, LeRoith D, Torbenson MS, Gores GJ, Wu H, Gao B, et al. Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. The Journal of Clinical Investigation. 116: 1843-52. PMID 16767220 DOI: 10.1172/Jci27282  0.485
2006 Stiles BL, Kuralwalla-Martinez C, Guo W, Gregorian C, Wang Y, Tian J, Magnuson MA, Wu H. Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes. Molecular and Cellular Biology. 26: 2772-81. PMID 16537919 DOI: 10.1128/Mcb.26.7.2772-2781.2006  0.457
2005 Stanger BZ, Stiles B, Lauwers GY, Bardeesy N, Mendoza M, Wang Y, Greenwood A, Cheng KH, McLaughlin M, Brown D, Depinho RA, Wu H, Melton DA, Dor Y. Pten constrains centroacinar cell expansion and malignant transformation in the pancreas. Cancer Cell. 8: 185-95. PMID 16169464 DOI: 10.1016/J.Ccr.2005.07.015  0.47
2005 Kurlawalla-Martinez C, Stiles B, Wang Y, Devaskar SU, Kahn BB, Wu H. Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue. Molecular and Cellular Biology. 25: 2498-510. PMID 15743841 DOI: 10.1128/Mcb.25.6.2498-2510.2005  0.36
2004 Stiles B, Groszer M, Wang S, Jiao J, Wu H. PTENless means more. Developmental Biology. 273: 175-84. PMID 15328005 DOI: 10.1016/J.Ydbio.2004.06.008  0.471
2004 Stiles B, Wang Y, Stahl A, Bassilian S, Lee WP, Kim YJ, Sherwin R, Devaskar S, Lesche R, Magnuson MA, Wu H. Live-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity Proceedings of the National Academy of Sciences of the United States of America. 101: 2082-2087. PMID 14769918 DOI: 10.1073/Pnas.0308617100  0.441
2004 Sundaresan G, Paulmurugan R, Berger F, Stiles B, Nagayama Y, Wu H, Gambhir SS. MicroPET imaging of Cre-loxP-mediated conditional activation of a herpes simplex virus type 1 thymidine kinase reporter gene. Gene Therapy. 11: 609-18. PMID 14724687 DOI: 10.1038/Sj.Gt.3302194  0.351
2002 Stiles B, Gilman V, Khanzenzon N, Lesche R, Li A, Qiao R, Liu X, Wu H. Essential Role of AKT-1/Protein Kinase Bα in PTEN-Controlled Tumorigenesis Molecular and Cellular Biology. 22: 3842-3851. PMID 11997518 DOI: 10.1128/Mcb.22.11.3842-3851.2002  0.485
2001 Neshat MS, Mellinghoff IK, Tran C, Stiles B, Thomas G, Petersen R, Frost P, Gibbons JJ, Wu H, Sawyers CL. Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. Proceedings of the National Academy of Sciences of the United States of America. 98: 10314-9. PMID 11504908 DOI: 10.1073/Pnas.171076798  0.482
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