Cynthia A. Derdeyn - Publications

Affiliations: 
Biological and Biomedical Sciences Emory University, Atlanta, GA 
Area:
Immunology, Molecular Biology, Virology Biology

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mopuri R, Welbourn S, Charles T, Ralli-Jain P, Rosales D, Burton S, Aftab A, Karunakaran K, Pellegrini K, Kilembe W, Karita E, Gnanakaran S, Upadhyay AA, Bosinger SE, Derdeyn CA. High throughput analysis of B cell dynamics and neutralizing antibody development during immunization with a novel clade C HIV-1 envelope. Plos Pathogens. 19: e1011717. PMID 37878666 DOI: 10.1371/journal.ppat.1011717  0.469
2022 Styles TM, Gangadhara S, Reddy PBJ, Sahoo A, Shiferaw A, Welbourn S, Kozlowski PA, Derdeyn CA, Velu V, Amara RR. V2 hotspot optimized MVA vaccine expressing stabilized HIV-1 Clade C envelope Gp140 delays acquisition of heterologous Clade C Tier 2 challenges in Mamu-A*01 negative Rhesus Macaques. Frontiers in Immunology. 13: 914969. PMID 35935987 DOI: 10.3389/fimmu.2022.914969  0.395
2022 Sahoo A, Jones AT, Cheedarla N, Gangadhara S, Roy V, Styles TM, Shiferaw A, Walter KL, Williams LD, Shen X, Ozorowski G, Lee WH, Burton S, Yi L, Song X, ... ... Derdeyn CA, et al. A clade C HIV-1 vaccine protects against heterologous SHIV infection by modulating IgG glycosylation and T helper response in macaques. Science Immunology. 7: eabl4102. PMID 35867800 DOI: 10.1126/sciimmunol.abl4102  0.415
2022 Welbourn S, Chakraborty S, Yang JE, Gleinich AS, Gangadhara S, Khan S, Ferrebee C, Yagnik B, Burton S, Charles T, Smith SA, Williams D, Mopuri R, Upadhyay AA, Thompson J, ... ... Derdeyn CA, et al. A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence. Plos Pathogens. 18: e1010488. PMID 35503780 DOI: 10.1371/journal.ppat.1010488  0.477
2021 Pino M, Pereira Ribeiro S, Pagliuzza A, Ghneim K, Khan A, Ryan E, Harper JL, King CT, Welbourn S, Micci L, Aldrete S, Delman KA, Stuart T, Lowe M, Brenchley JM, ... Derdeyn CA, et al. Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART. Plos Pathogens. 17: e1009825. PMID 34449812 DOI: 10.1371/journal.ppat.1009825  0.353
2021 Charles TP, Burton SL, Arunachalam PS, Cottrell CA, Sewall LM, Bollimpelli VS, Gangadhara S, Dey AK, Ward AB, Shaw GM, Hunter E, Amara RR, Pulendran B, van Gils MJ, Derdeyn CA. The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection. Plos Pathogens. 17: e1009257. PMID 33556148 DOI: 10.1371/journal.ppat.1009257  0.475
2020 Arunachalam PS, Charles TP, Joag V, Bollimpelli VS, Scott MKD, Wimmers F, Burton SL, Labranche CC, Petitdemange C, Gangadhara S, Styles TM, Quarnstrom CF, Walter KA, Ketas TJ, Legere T, ... ... Derdeyn CA, et al. T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers. Nature Medicine. PMID 32393800 DOI: 10.1038/S41591-020-0858-8  0.534
2020 McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Sahay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, ... ... Derdeyn CA, et al. Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8 cells. Nature. PMID 32015546 DOI: 10.1038/S41586-020-2002-9  0.466
2020 McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Suhay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, ... ... Derdeyn CA, et al. Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8 cells. Nature. PMID 31969705 DOI: 10.1038/S41586-020-1946-0  0.578
2019 Chamcha V, Reddy PBJ, Kannanganat S, Wilkins C, Gangadhara S, Velu V, Green R, Law GL, Chang J, Bowen JR, Kozlowski PA, Lifton M, Santra S, Legere T, Chea LS, ... ... Derdeyn CA, et al. Strong T1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy. Science Translational Medicine. 11. PMID 31748228 DOI: 10.1126/Scitranslmed.Aav1800  0.477
2019 Charles TP, Derdeyn CA. Striking a balance in an antibody network: A roadmap for HIV-1 vaccines. The Journal of Clinical Investigation. PMID 31589166 DOI: 10.1172/Jci132535  0.543
2019 Styles TM, Gangadhara S, Reddy PBJ, Hicks S, LaBranche CC, Montefiori DC, Derdeyn CA, Kozlowski PA, Velu V, Amara RR. HIV C.1086 Envelope Gp140 Protein Boosts Following DNA/MVA Vaccination Fail to Enhance Heterologous Anti-V1V2 Antibody Response and Protection Against Clade C SHIV Challenge. Journal of Virology. PMID 31341049 DOI: 10.1128/Jvi.00934-19  0.557
2019 Petitdemange C, Kasturi SP, Kozlowski PA, Nabi R, Quarnstrom CF, Reddy PBJ, Derdeyn CA, Spicer LM, Patel P, Legere T, Kovalenkov YO, Labranche CC, Villinger F, Tomai M, Vasilakos J, et al. Vaccine induction of antibodies and tissue-resident CD8+ T cells enhances protection against mucosal SHIV-infection in young macaques. Jci Insight. 4. PMID 30830870 DOI: 10.1172/Jci.Insight.126047  0.538
2019 Burton S, Spicer LM, Charles TP, Gangadhara S, Reddy PB, Styles TM, Velu V, Kasturi SP, Legere T, Hunter E, Pulendran B, Amara R, Hraber P, Derdeyn CA. Clade C HIV-1 envelope vaccination regimens differ in their ability to elicit antibodies with moderate neutralization breadth against genetically diverse tier 2 HIV-1 envelope variants. Journal of Virology. PMID 30651354 DOI: 10.1128/Jvi.01846-18  0.529
2018 Smith SA, Burton SL, Kilembe W, Lakhi S, Karita E, Price M, Allen S, Derdeyn CA. VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120. Frontiers in Immunology. 9: 3163. PMID 30697215 DOI: 10.3389/Fimmu.2018.03163  0.579
2017 Shacklett BL, Derdeyn CA, Folayan MO, Landovitz R, Anthony C, Behrens AJ, Hope T, Landais E, Leal L, Marrazzo JM, Morris L, Mugo N, Ngure K, Noseda V, Ranasinghe S, et al. HIVR4P 2016, Partnering for Prevention: Conference Summary and Highlights. Aids Research and Human Retroviruses. PMID 28649869 DOI: 10.1089/Aid.2017.0125  0.463
2017 Smith SA, Derdeyn CA. New connections: Cell to cell HIV-1 transmission, resistance to broadly neutralizing antibodies, and an envelope sorting motif. Journal of Virology. PMID 28250119 DOI: 10.1128/Jvi.00149-17  0.571
2017 Smith SA, Burton S, Kilembe W, Lakhi S, Karita E, Price M, Allen S, Hunter E, Derdeyn C. P-C2 Characterization of the early antibody landscape in HIV-1 infected individuals who develop poor to elite levels of neutralization breadth Jaids Journal of Acquired Immune Deficiency Syndromes. 74: 77. DOI: 10.1097/01.Qai.0000513916.33659.2A  0.562
2017 Derdeyn C. G-110 Events in early HIV-1 infection that prime the development of heterologous neutralization breadth Jaids Journal of Acquired Immune Deficiency Syndromes. 74: 60. DOI: 10.1097/01.Qai.0000513864.26888.Ed  0.5
2016 Kasturi SP, Kozlowski PA, Nakaya HI, Burger MC, Russo P, Pham M, Kovalenkov Y, Silveira EL, Havenar-Daughton C, Burton SL, Kilgore KM, Johnson MJ, Nabi R, Legere T, Sher ZJ, ... ... Derdeyn CA, et al. Adjuvanting an SIV vaccine with TLR ligands encapsulated in nanoparticles induces persistent antibody responses and enhanced protection in TRIM5α restrictive macaques. Journal of Virology. PMID 27928002 DOI: 10.1128/Jvi.01844-16  0.385
2016 Smith SA, Burton SL, Kilembe W, Lakhi S, Karita E, Price M, Allen S, Hunter E, Derdeyn CA. Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth. Plos Pathogens. 12: e1005989. PMID 27851829 DOI: 10.1371/Journal.Ppat.1005989  0.54
2016 Tian J, López CA, Derdeyn CA, Jones MS, Pinter A, Korber B, Gnanakaran S. Effect of Glycosylation on an Immunodominant Region in the V1V2 Variable Domain of the HIV-1 Envelope gp120 Protein. Plos Computational Biology. 12: e1005094. PMID 27716795 DOI: 10.1371/Journal.Pcbi.1005094  0.493
2016 Cartwright EK, Spicer L, Smith SA, Lee D, Fast R, Paganini S, Lawson BO, Nega M, Easley K, Schmitz JE, Bosinger SE, Paiardini M, Chahroudi A, Vanderford TH, Estes JD, ... ... Derdeyn CA, et al. CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy. Immunity. 45: 656-68. PMID 27653601 DOI: 10.1016/J.Immuni.2016.08.018  0.521
2016 Smith SA, Derdeyn CA. Harnessing the protective potential of HIV-1 neutralizing antibodies. F1000research. 5. PMID 26918160 DOI: 10.12688/F1000Research.7254.1  0.525
2015 Smith SA, Kilgore KM, Kasturi SP, Pulendran B, Hunter E, Amara RR, Derdeyn CA. Signatures in SIVsmE660 Envelope gp120 are Associated with Mucosal Transmission but not Vaccination Breakthrough in Rhesus Macaques. Journal of Virology. PMID 26676777 DOI: 10.1128/Jvi.02711-15  0.485
2015 Smith SA, Derdeyn CA. A pathway to HIV-1 neutralization breadth. Nature Medicine. 21: 1246-7. PMID 26540383 DOI: 10.1038/Nm.3989  0.538
2015 Gu L, Krendelchtchikova V, Krendelchtchikov A, Farrow AL, Derdeyn CA, Matthews QL. Adenoviral vectors elicit humoral immunity against variable loop 2 of clade C HIV-1 gp120 via "Antigen Capsid-Incorporation" strategy. Virology. 487: 75-84. PMID 26499044 DOI: 10.1016/J.Virol.2015.10.010  0.533
2015 Burton SL, Kilgore KM, Smith SA, Reddy S, Hunter E, Robinson HL, Silvestri G, Amara RR, Derdeyn CA. Breakthrough of SIV strain smE660 challenge in SIV strain mac239-vaccinated rhesus macaques despite potent autologous neutralizing antibody responses. Proceedings of the National Academy of Sciences of the United States of America. PMID 26261312 DOI: 10.1073/Pnas.1509731112  0.518
2015 Elliott ST, Wetzel KS, Francella N, Bryan S, Romero DC, Riddick NE, Shaheen F, Vanderford T, Derdeyn CA, Silvestri G, Paiardini M, Collman RG. Dualtropic CXCR6/CCR5 Simian Immunodeficiency Virus (SIV) Infection of Sooty Mangabey Primary Lymphocytes: Distinct Coreceptor Use in Natural versus Pathogenic Hosts of SIV. Journal of Virology. 89: 9252-61. PMID 26109719 DOI: 10.1128/Jvi.01236-15  0.496
2015 Peters PJ, Gonzalez-Perez MP, Musich T, Moore Simas TA, Lin R, Morse AN, Shattock RJ, Derdeyn CA, Clapham PR. Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes. Retrovirology. 12: 48. PMID 26055104 DOI: 10.1186/S12977-015-0176-2  0.449
2015 Kilgore KM, Murphy MK, Burton SL, Wetzel KS, Smith SA, Xiao P, Reddy S, Francella N, Sodora DL, Silvestri G, Cole KS, Villinger F, Robinson JE, Pulendran B, Hunter E, ... ... Derdeyn CA, et al. Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope. Journal of Virology. 89: 8130-51. PMID 26018167 DOI: 10.1128/Jvi.01221-14  0.546
2015 Musich T, O'Connell O, Gonzalez-Perez MP, Derdeyn CA, Peters PJ, Clapham PR. HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages. Retrovirology. 12: 25. PMID 25809903 DOI: 10.1186/S12977-015-0141-0  0.482
2015 Yue L, Pfafferott KJ, Baalwa J, Conrod K, Dong CC, Chui C, Rong R, Claiborne DT, Prince JL, Tang J, Ribeiro RM, Cormier E, Hahn BH, Perelson AS, Shaw GM, ... ... Derdeyn CA, et al. Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients. Plos Pathogens. 11: e1004565. PMID 25569444 DOI: 10.1371/Journal.Ppat.1004565  0.59
2014 Micci L, Alvarez X, Iriele RI, Ortiz AM, Ryan ES, McGary CS, Deleage C, McAtee BB, He T, Apetrei C, Easley K, Pahwa S, Collman RG, Derdeyn CA, Davenport MP, et al. CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells. Plos Pathogens. 10: e1004467. PMID 25356757 DOI: 10.1371/Journal.Ppat.1004467  0.492
2014 Li Q, Zeng M, Duan L, Voss JE, Smith AJ, Pambuccian S, Shang L, Wietgrefe S, Southern PJ, Reilly CS, Skinner PJ, Zupancic ML, Carlis JV, Piatak M, Waterman D, ... ... Derdeyn CA, et al. Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry. Journal of Immunology (Baltimore, Md. : 1950). 193: 3113-25. PMID 25135832 DOI: 10.4049/Jimmunol.1400820  0.443
2014 Basu D, Xiao P, Ende Z, Bere A, Britt WJ, Mulenga J, Kilembe W, Allen SA, Derdeyn CA, Hunter E. Low antibody-dependent cellular cytotoxicity responses in Zambians prior to HIV-1 intrasubtype C superinfection. Virology. 462: 295-8. PMID 25004405 DOI: 10.1016/J.Virol.2014.06.016  0.612
2014 Derdeyn CA, Moore PL, Morris L. Development of broadly neutralizing antibodies from autologous neutralizing antibody responses in HIV infection. Current Opinion in Hiv and Aids. 9: 210-6. PMID 24662931 DOI: 10.1097/Coh.0000000000000057  0.599
2014 Chahroudi A, Cartwright E, Lee ST, Mavigner M, Carnathan DG, Lawson B, Carnathan PM, Hashempoor T, Murphy MK, Meeker T, Ehnert S, Souder C, Else JG, Cohen J, Collman RG, ... ... Derdeyn CA, et al. Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques. Plos Pathogens. 10: e1003958. PMID 24604066 DOI: 10.1371/Journal.Ppat.1003958  0.445
2014 Cavrois M, Neidleman J, Santiago ML, Derdeyn CA, Hunter E, Greene WC. Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains. Journal of Virology. 88: 2083-94. PMID 24335304 DOI: 10.1128/Jvi.02308-13  0.464
2013 Francella N, Elliott ST, Yi Y, Gwyn SE, Ortiz AM, Li B, Silvestri G, Paiardini M, Derdeyn CA, Collman RG. Decreased plasticity of coreceptor use by CD4-independent SIV Envs that emerge in vivo. Retrovirology. 10: 133. PMID 24219995 DOI: 10.1186/1742-4690-10-133  0.367
2013 Francella N, Gwyn SE, Yi Y, Li B, Xiao P, Elliott ST, Ortiz AM, Hoxie JA, Paiardini M, Silvestri G, Derdeyn CA, Collman RG. CD4+ T cells support production of simian immunodeficiency virus Env antibodies that enforce CD4-dependent entry and shape tropism in vivo. Journal of Virology. 87: 9719-32. PMID 23824793 DOI: 10.1128/Jvi.01254-13  0.452
2013 Sethi A, Tian J, Derdeyn CA, Korber B, Gnanakaran S. A mechanistic understanding of allosteric immune escape pathways in the HIV-1 envelope glycoprotein. Plos Computational Biology. 9: e1003046. PMID 23696718 DOI: 10.1371/Journal.Pcbi.1003046  0.496
2013 Murphy MK, Yue L, Pan R, Boliar S, Sethi A, Tian J, Pfafferot K, Karita E, Allen SA, Cormier E, Goepfert PA, Borrow P, Robinson JE, Gnanakaran S, Hunter E, ... ... Derdeyn CA, et al. Viral escape from neutralizing antibodies in early subtype A HIV-1 infection drives an increase in autologous neutralization breadth. Plos Pathogens. 9: e1003173. PMID 23468623 DOI: 10.1371/Journal.Ppat.1003173  0.598
2012 Prince JL, Claiborne DT, Carlson JM, Schaefer M, Yu T, Lahki S, Prentice HA, Yue L, Vishwanathan SA, Kilembe W, Goepfert P, Price MA, Gilmour J, Mulenga J, Farmer P, ... Derdeyn CA, et al. Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis. Plos Pathogens. 8: e1003041. PMID 23209412 DOI: 10.1371/Journal.Ppat.1003041  0.56
2012 Archary D, Rong R, Gordon ML, Boliar S, Madiga M, Gray ES, Dugast AS, Hermanus T, Goulder PJ, Coovadia HM, Werner L, Morris L, Alter G, Derdeyn CA, Ndung'u T. Characterization of anti-HIV-1 neutralizing and binding antibodies in chronic HIV-1 subtype C infection. Virology. 433: 410-20. PMID 22995189 DOI: 10.1016/J.Virol.2012.08.033  0.53
2012 Basu D, Kraft CS, Murphy MK, Campbell PJ, Yu T, Hraber PT, Irene C, Pinter A, Chomba E, Mulenga J, Kilembe W, Allen SA, Derdeyn CA, Hunter E. HIV-1 subtype C superinfected individuals mount low autologous neutralizing antibody responses prior to intrasubtype superinfection. Retrovirology. 9: 76. PMID 22995123 DOI: 10.1186/1742-4690-9-76  0.57
2012 Garber DA, O'Mara LA, Gangadhara S, McQuoid M, Zhang X, Zheng R, Gill K, Verma M, Yu T, Johnson B, Li B, Derdeyn CA, Ibegbu C, Altman JD, Hunter E, et al. Deletion of specific immune-modulatory genes from modified vaccinia virus Ankara-based HIV vaccines engenders improved immunogenicity in rhesus macaques. Journal of Virology. 86: 12605-15. PMID 22973033 DOI: 10.1128/Jvi.00246-12  0.577
2012 Boliar S, Murphy MK, Tran TC, Carnathan DG, Armstrong WS, Silvestri G, Derdeyn CA. B-lymphocyte dysfunction in chronic HIV-1 infection does not prevent cross-clade neutralization breadth. Journal of Virology. 86: 8031-40. PMID 22623771 DOI: 10.1128/Jvi.00771-12  0.5
2012 Manigart O, Boeras DI, Karita E, Hawkins PA, Vwalika C, Makombe N, Mulenga J, Derdeyn CA, Allen S, Hunter E. A gp41-based heteroduplex mobility assay provides rapid and accurate assessment of intrasubtype epidemiological linkage in HIV type 1 heterosexual transmission Pairs. Aids Research and Human Retroviruses. 28: 1745-55. PMID 22587371 DOI: 10.1089/Aid.2012.0023  0.461
2012 Kraft CS, Basu D, Hawkins PA, Hraber PT, Chomba E, Mulenga J, Kilembe W, Khu NH, Derdeyn CA, Allen SA, Manigart O, Hunter E. Timing and source of subtype-C HIV-1 superinfection in the newly infected partner of Zambian couples with disparate viruses. Retrovirology. 9: 22. PMID 22433432 DOI: 10.1186/1742-4690-9-22  0.555
2012 Elliott ST, Riddick NE, Francella N, Paiardini M, Vanderford TH, Li B, Apetrei C, Sodora DL, Derdeyn CA, Silvestri G, Collman RG. Cloning and analysis of sooty mangabey alternative coreceptors that support simian immunodeficiency virus SIVsmm entry independently of CCR5. Journal of Virology. 86: 898-908. PMID 22090107 DOI: 10.1128/Jvi.06415-11  0.494
2012 Archary D, Rong R, Gordon ML, Boliar S, Gray ES, Dugast A, Hermanus T, Goulder PJ, Coovadia HM, Morris L, Alter G, Derdeyn C, Ndung'u T. Neutralizing and non-neutralizing antibody responses in HIV-1 subtype C chronically infected patients with divergent rates of disease progression Retrovirology. 9: 75. DOI: 10.1186/1742-4690-9-S2-P75  0.586
2012 Basu D, Kraft C, Campbell P, Murphy M, Yu T, Hraber P, Chomba E, Mulenga J, Kilembe W, Allen S, Derdeyn C, Hunter E. Intrasubtype C superinfected individuals mount delayed and low-titer autologous neutralizing antibody responses prior to superinfection Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P159  0.553
2012 Murphy M, Yue L, Pan R, Boliar S, Sethi A, Karita E, Allen S, Cormier E, Robinson J, Gnanakaran S, Hunter E, Kong X, Derdeyn C. Sequential exposure to specific antibody escape mutations may program neutralization breadth during subtype A HIV-1 infection Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P104  0.589
2012 Murphy MK, Boliar S, Tran TC, Carnathan DG, Armstrong W, Silvestri G, Derdeyn C. Heterologous neutralization breadth persists despite B-lymphocyte dysfunction in chronic HIV-1 infection Retrovirology. 9: 103. DOI: 10.1186/1742-4690-9-S2-P103  0.54
2012 Krachmarov C, Revesz K, Prattipati R, Reichman C, Li B, Derdeyn C, Sarlo J, Zingman B, Honnen W, Pinter A. Characterization of V1/V2-specific antibodies present in broadly neutralizing plasma isolated from HIV-1 infected individuals Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-O30  0.555
2012 Claiborne D, Prince J, Schaefer M, Yue L, Prentice H, Derdeyn C, Kaslow R, Goepfert P, Hunter E. 131 Characteristics of Transmitted Founder Viruses Jaids Journal of Acquired Immune Deficiency Syndromes. 59: 54. DOI: 10.1097/01.Qai.0000413751.00256.B6  0.342
2011 Boeras DI, Hraber PT, Hurlston M, Evans-Strickfaden T, Bhattacharya T, Giorgi EE, Mulenga J, Karita E, Korber BT, Allen S, Hart CE, Derdeyn CA, Hunter E. Role of donor genital tract HIV-1 diversity in the transmission bottleneck. Proceedings of the National Academy of Sciences of the United States of America. 108: E1156-63. PMID 22065783 DOI: 10.1073/Pnas.1103764108  0.507
2011 Ortiz AM, Klatt NR, Li B, Yi Y, Tabb B, Hao XP, Sternberg L, Lawson B, Carnathan PM, Cramer EM, Engram JC, Little DM, Ryzhova E, Gonzalez-Scarano F, Paiardini M, ... ... Derdeyn CA, et al. Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques. The Journal of Clinical Investigation. 121: 4433-45. PMID 22005304 DOI: 10.1172/Jci46023  0.533
2011 Lynch RM, Rong R, Boliar S, Sethi A, Li B, Mulenga J, Allen S, Robinson JE, Gnanakaran S, Derdeyn CA. The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter. Journal of Virology. 85: 905-15. PMID 20980495 DOI: 10.1128/Jvi.02006-10  0.72
2011 Cavrois M, Neidleman J, Galloway N, Derdeyn CA, Hunter E, Greene WC. Measuring HIV fusion mediated by envelopes from primary viral isolates. Methods (San Diego, Calif.). 53: 34-8. PMID 20554044 DOI: 10.1016/J.Ymeth.2010.05.010  0.591
2011 Sethi A, Derdeyn C, Korber B, Gnanakaran S. Network Analysis of the Communication Pathways in HIV-1 Envelope Proteins For Mechanistic Understanding of Immune Escape Biophysical Journal. 100: 227a-228a. DOI: 10.1016/J.Bpj.2010.12.1456  0.47
2010 Riddick NE, Hermann EA, Loftin LM, Elliott ST, Wey WC, Cervasi B, Taaffe J, Engram JC, Li B, Else JG, Li Y, Hahn BH, Derdeyn CA, Sodora DL, Apetrei C, et al. A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo. Plos Pathogens. 6: e1001064. PMID 20865163 DOI: 10.1371/Journal.Ppat.1001064  0.474
2010 Lynch RM, Rong R, Li B, Shen T, Honnen W, Mulenga J, Allen S, Pinter A, Gnanakaran S, Derdeyn CA. Subtype-specific conservation of isoleucine 309 in the envelope V3 domain is linked to immune evasion in subtype C HIV-1 infection. Virology. 404: 59-70. PMID 20494390 DOI: 10.1016/J.Virol.2010.04.010  0.699
2010 Li B, Stefano-Cole K, Kuhrt DM, Gordon SN, Else JG, Mulenga J, Allen S, Sodora DL, Silvestri G, Derdeyn CA. Nonpathogenic simian immunodeficiency virus infection of sooty mangabeys is not associated with high levels of autologous neutralizing antibodies. Journal of Virology. 84: 6248-53. PMID 20375163 DOI: 10.1128/Jvi.00295-10  0.597
2010 Alexander M, Lynch R, Mulenga J, Allen S, Derdeyn CA, Hunter E. Donor and recipient envs from heterosexual human immunodeficiency virus subtype C transmission pairs require high receptor levels for entry. Journal of Virology. 84: 4100-4. PMID 20147398 DOI: 10.1128/Jvi.02068-09  0.69
2009 Keele BF, Derdeyn CA. Genetic and antigenic features of the transmitted virus. Current Opinion in Hiv and Aids. 4: 352-7. PMID 20048697 DOI: 10.1097/Coh.0B013E32832D9Fef  0.519
2009 Rong R, Li B, Lynch RM, Haaland RE, Murphy MK, Mulenga J, Allen SA, Pinter A, Shaw GM, Hunter E, Robinson JE, Gnanakaran S, Derdeyn CA. Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways. Plos Pathogens. 5: e1000594. PMID 19763269 DOI: 10.1371/Journal.Ppat.1000594  0.738
2009 Isaacman-Beck J, Hermann EA, Yi Y, Ratcliffe SJ, Mulenga J, Allen S, Hunter E, Derdeyn CA, Collman RG. Heterosexual transmission of human immunodeficiency virus type 1 subtype C: Macrophage tropism, alternative coreceptor use, and the molecular anatomy of CCR5 utilization. Journal of Virology. 83: 8208-20. PMID 19515785 DOI: 10.1128/Jvi.00296-09  0.446
2009 Salazar-Gonzalez JF, Salazar MG, Keele BF, Learn GH, Giorgi EE, Li H, Decker JM, Wang S, Baalwa J, Kraus MH, Parrish NF, Shaw KS, Guffey MB, Bar KJ, Davis KL, ... ... Derdeyn CA, et al. Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. The Journal of Experimental Medicine. 206: 1273-89. PMID 19487424 DOI: 10.1084/Jem.20090378  0.589
2009 Zhao C, Crews CJ, Derdeyn CA, Blackwell JL. Lac-regulated system for generating adenovirus 5 vaccine vectors expressing cytolytic human immunodeficiency virus 1 genes. Journal of Virological Methods. 160: 101-10. PMID 19409930 DOI: 10.1016/J.Jviromet.2009.04.028  0.386
2009 Lynch RM, Shen T, Gnanakaran S, Derdeyn CA. Appreciating HIV type 1 diversity: subtype differences in Env. Aids Research and Human Retroviruses. 25: 237-48. PMID 19327047 DOI: 10.1089/Aid.2008.0219  0.725
2009 Haaland RE, Hawkins PA, Salazar-Gonzalez J, Johnson A, Tichacek A, Karita E, Manigart O, Mulenga J, Keele BF, Shaw GM, Hahn BH, Allen SA, Derdeyn CA, Hunter E. Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1. Plos Pathogens. 5: e1000274. PMID 19165325 DOI: 10.1371/Journal.Ppat.1000274  0.418
2009 Rong R, Li B, Haaland RE, Murphy MK, Mulenga J, Allen SA, Blackwell JL, Pinter A, Shaw GM, Gnanakaran S, Hunter E, Robinson JE, Derdeyn CA. P09-12. Autologous neutralizing antibodies in early subtype C HIV-1 infection target variable regions of envelope and drive multiple pathways of viral escape Retrovirology. 6: P125. DOI: 10.1186/1742-4690-6-S3-P125  0.397
2009 Murphy MK, Rong R, Li B, Mulenga J, Allen SA, Gnanakaran S, Derdeyn CA. P09-01. Mutation of the gp120 alpha2 helix in early subtype C HIV-1 infection fails to alter neutralization sensitivity or efficiency of in vitro replication Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P114  0.532
2009 Rong R, Li B, Lynch RM, Mulenga J, Allen S, Hunter E, Blackwell JL, Derdeyn CA. 107 Escape from Neutralizing Antibody in Early Subtype C HIV-1 Infection Jaids Journal of Acquired Immune Deficiency Syndromes. 51: 1. DOI: 10.1097/01.Qai.0000351064.57428.B1  0.733
2008 Derdeyn CA, Hunter E. Viral characteristics of transmitted HIV. Current Opinion in Hiv and Aids. 3: 16-21. PMID 19372939 DOI: 10.1097/Coh.0B013E3282F2982C  0.423
2008 Goepfert PA, Lumm W, Farmer P, Matthews P, Prendergast A, Carlson JM, Derdeyn CA, Tang J, Kaslow RA, Bansal A, Yusim K, Heckerman D, Mulenga J, Allen S, Goulder PJ, et al. Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients. The Journal of Experimental Medicine. 205: 1009-17. PMID 18426987 DOI: 10.1084/Jem.20072457  0.524
2008 Salazar-Gonzalez JF, Bailes E, Pham KT, Salazar MG, Guffey MB, Keele BF, Derdeyn CA, Farmer P, Hunter E, Allen S, Manigart O, Mulenga J, Anderson JA, Swanstrom R, Haynes BF, et al. Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing. Journal of Virology. 82: 3952-70. PMID 18256145 DOI: 10.1128/Jvi.02660-07  0.523
2007 Brockman MA, Schneidewind A, Lahaie M, Schmidt A, Miura T, Desouza I, Ryvkin F, Derdeyn CA, Allen S, Hunter E, Mulenga J, Goepfert PA, Walker BD, Allen TM. Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A. Journal of Virology. 81: 12608-18. PMID 17728232 DOI: 10.1128/Jvi.01369-07  0.525
2007 Rong R, Gnanakaran S, Decker JM, Bibollet-Ruche F, Taylor J, Sfakianos JN, Mokili JL, Muldoon M, Mulenga J, Allen S, Hahn BH, Shaw GM, Blackwell JL, Korber BT, Hunter E, ... Derdeyn CA, et al. Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1. Journal of Virology. 81: 5658-68. PMID 17360739 DOI: 10.1128/Jvi.00257-07  0.439
2007 Gnanakaran S, Lang D, Daniels M, Bhattacharya T, Derdeyn CA, Korber B. Clade-specific differences between human immunodeficiency virus type 1 clades B and C: diversity and correlations in C3-V4 regions of gp120. Journal of Virology. 81: 4886-91. PMID 17166900 DOI: 10.1128/Jvi.01954-06  0.39
2007 Rong R, Bibollet-Ruche F, Mulenga J, Allen S, Blackwell JL, Derdeyn CA. Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infection. Journal of Virology. 81: 1350-9. PMID 17079307 DOI: 10.1128/Jvi.01839-06  0.447
2006 Li M, Salazar-Gonzalez JF, Derdeyn CA, Morris L, Williamson C, Robinson JE, Decker JM, Li Y, Salazar MG, Polonis VR, Mlisana K, Karim SA, Hong K, Greene KM, Bilska M, et al. Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa. Journal of Virology. 80: 11776-90. PMID 16971434 DOI: 10.1128/Jvi.01730-06  0.614
2006 Johnson RW, Li B, Sunay S, Moore RH, Mulenga J, Hunter E, Allen S, Blackwell JL, Derdeyn CA. Real-time PCR quantitation of subtype C HIV DNA in a Zambian discordant couple cohort. Aids Research and Human Retroviruses. 22: 438-44. PMID 16706621 DOI: 10.1089/Aid.2006.22.438  0.345
2006 Li B, Decker JM, Johnson RW, Bibollet-Ruche F, Wei X, Mulenga J, Allen S, Hunter E, Hahn BH, Shaw GM, Blackwell JL, Derdeyn CA. Evidence for potent autologous neutralizing antibody titers and compact envelopes in early infection with subtype C human immunodeficiency virus type 1. Journal of Virology. 80: 5211-8. PMID 16699001 DOI: 10.1128/Jvi.00201-06  0.526
2005 Derdeyn CA, Silvestri G. Viral and host factors in the pathogenesis of HIV infection Current Opinion in Immunology. 17: 366-373. PMID 15955686 DOI: 10.1016/J.Coi.2005.06.001  0.49
2005 Decker JM, Bibollet-Ruche F, Wei X, Wang S, Levy DN, Wang W, Delaporte E, Peeters M, Derdeyn CA, Allen S, Hunter E, Saag MS, Hoxie JA, Hahn BH, Kwong PD, et al. Antigenic conservation and immunogenicity of the HIV coreceptor binding site. The Journal of Experimental Medicine. 201: 1407-19. PMID 15867093 DOI: 10.1084/Jem.20042510  0.619
2005 Neumann T, Hagmann I, Lohrengel S, Heil ML, Derdeyn CA, Kräusslich HG, Dittmar MT. T20-insensitive HIV-1 from naive patients exhibits high viral fitness in a novel dual-color competition assay on primary cells. Virology. 333: 251-62. PMID 15721359 DOI: 10.1016/j.virol.2004.12.035  0.385
2004 Derdeyn CA, Decker JM, Bibollet-Ruche F, Mokili JL, Muldoon M, Denham SA, Heil ML, Kasolo F, Musonda R, Hahn BH, Shaw GM, Korber BT, Allen S, Hunter E. Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission. Science (New York, N.Y.). 303: 2019-22. PMID 15044802 DOI: 10.1126/Science.1093137  0.546
2002 Reeves JD, Gallo SA, Ahmad N, Miamidian JL, Harvey PE, Sharron M, Pohlmann S, Sfakianos JN, Derdeyn CA, Blumenthal R, Hunter E, Doms RW. Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics. Proceedings of the National Academy of Sciences of the United States of America. 99: 16249-54. PMID 12444251 DOI: 10.1073/Pnas.252469399  0.416
2002 Trask SA, Derdeyn CA, Fideli U, Chen Y, Meleth S, Kasolo F, Musonda R, Hunter E, Gao F, Allen S, Hahn BH. Molecular epidemiology of human immunodeficiency virus type 1 transmission in a heterosexual cohort of discordant couples in Zambia. Journal of Virology. 76: 397-405. PMID 11739704 DOI: 10.1128/Jvi.76.1.397-405.2002  0.494
2001 Li H, Haviv YS, Derdeyn CA, Lam J, Coolidge C, Hunter E, Curiel DT, Blackwell JL. Human immunodeficiency virus type 1-mediated syncytium formation is compatible with adenovirus replication and facilitates efficient dispersion of viral gene products and de novo-synthesized virus particles. Human Gene Therapy. 12: 2155-65. PMID 11779400 DOI: 10.1089/10430340152710504  0.417
2001 Derdeyn CA, Decker JM, Sfakianos JN, Zhang Z, O'Brien WA, Ratner L, Shaw GM, Hunter E. Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor. Journal of Virology. 75: 8605-14. PMID 11507206 DOI: 10.1128/Jvi.75.18.8605-8614.2001  0.449
2000 Piller SC, Dubay JW, Derdeyn CA, Hunter E. Mutational analysis of conserved domains within the cytoplasmic tail of gp41 from human immunodeficiency virus type 1: effects on glycoprotein incorporation and infectivity. Journal of Virology. 74: 11717-23. PMID 11090171 DOI: 10.1128/Jvi.74.24.11717-11723.2000  0.389
1999 Derdeyn CA, Kilby JM, Miralles GD, Li LF, Sfakianos G, Saag MS, Hockett RD, Bucy RP. Evaluation of distinct blood lymphocyte populations in human immunodeficiency virus type 1-infected subjects in the absence or presence of effective therapy. The Journal of Infectious Diseases. 180: 1851-62. PMID 10558941 DOI: 10.1086/315117  0.416
1999 Derdeyn CA, Costello C, Kilby JM, Sfakianos G, Saag MS, Kaslow R, Bucy RP. Correlation between circulating stromal cell-derived factor 1 levels and CD4+ cell count in human immunodeficiency virus type 1-infected individuals. Aids Research and Human Retroviruses. 15: 1063-71. PMID 10461826 DOI: 10.1089/088922299310359  0.447
1999 Hockett RD, Kilby JM, Derdeyn CA, Saag MS, Sillers M, Squires K, Chiz S, Nowak MA, Shaw GM, Bucy RP. Constant mean viral copy number per infected cell in tissues regardless of high, low, or undetectable plasma HIV RNA. The Journal of Experimental Medicine. 189: 1545-54. PMID 10330433 DOI: 10.1084/Jem.189.10.1545  0.364
1999 Bucy RP, Hockett RD, Derdeyn CA, Saag MS, Squires K, Sillers M, Mitsuyasu RT, Kilby JM. Initial increase in blood CD4(+) lymphocytes after HIV antiretroviral therapy reflects redistribution from lymphoid tissues. The Journal of Clinical Investigation. 103: 1391-8. PMID 10330421 DOI: 10.1172/Jci5863  0.418
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