Matthew C. Franklin, Ph.D.
Affiliations: | 2001 | Yale University, New Haven, CT |
Area:
Biochemistry, structural chemistryGoogle:
"Matthew Franklin"Mean distance: 8.32
Parents
Sign in to add mentor| Thomas A. Steitz | grad student | 2001 | Yale | |
| (Structure of an RB69 DNA polymerase ternary complex.) | ||||
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Publications
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| Hansen J, Baum A, Pascal KE, et al. (2020) Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail. Science (New York, N.Y.) |
| Atanasio A, Franklin M, Ben L, et al. (2020) Targeting birch allergy with monoclonal IgG antibodies that bind allergen and prevent IgE effector cell activation Journal of Allergy and Clinical Immunology. 145: AB62 |
| Macdonald LE, Meagher KA, Franklin MC, et al. (2019) Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties. Proceedings of the National Academy of Sciences of the United States of America |
| Orengo JM, Radin AR, Kamat V, et al. (2018) Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement. Nature Communications. 9: 1421 |
| Franklin MC, Rudolph MJ, Ginter C, et al. (2016) Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins |
| Franklin MC, Cheung J, Rudolph MJ, et al. (2015) Structural Genomics for Drug Design against the Pathogen Coxiella burnetii. Proteins |
| Dutta K, Varshney AK, Franklin MC, et al. (2015) Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies. The Journal of Biological Chemistry. 290: 6715-30 |
| Rudolph MJ, Vance DJ, Cheung J, et al. (2014) Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies. Journal of Molecular Biology. 426: 3057-68 |
| Flygare JA, Beresini M, Budha N, et al. (2012) Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152). Journal of Medicinal Chemistry. 55: 4101-13 |
| Franklin MC, Navarro EC, Wang Y, et al. (2011) The structural basis for the function of two anti-VEGF receptor 2 antibodies. Structure (London, England : 1993). 19: 1097-107 |