Kai Tan, PhD

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Computational Biology
Website:
https://www.med.upenn.edu/apps/faculty/index.php/g275/p8885111
Google:
"Kai Tan"
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Publications

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Hsu J, Huang HT, Lee CT, et al. (2020) CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation. Proceedings of the National Academy of Sciences of the United States of America
Gao P, Chen C, Howell ED, et al. (2020) Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells. Genes & Development
Zhu Q, Gao P, Tober J, et al. (2020) Developmental trajectory of pre-hematopoietic stem cell formation from endothelium. Blood
Chen C, Yu W, Tober J, et al. (2019) Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells. Cell Reports. 29: 4200-4211.e7
Packer JS, Zhu Q, Huynh C, et al. (2019) A lineage-resolved molecular atlas of embryogenesis at single-cell resolution. Science (New York, N.Y.)
Hu Y, Chen CH, Ding YY, et al. (2019) Optimal control nodes in disease-perturbed networks as targets for combination therapy. Nature Communications. 10: 2180
Peng T, Zhu Q, Yin P, et al. (2019) SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data. Genome Biology. 20: 88
Taylor DM, Aronow BJ, Tan K, et al. (2019) The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Developmental Cell
Nicetto D, Donahue G, Jain T, et al. (2019) H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science (New York, N.Y.)
Estevez B, Borst S, Jarocha DJ, et al. (2019) The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction Blood. 134: 220-220
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