Joseph R. Mazzulli, Ph.D.
Affiliations: | 2007 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Neuroscience BiologyGoogle:
"Joseph Mazzulli"Mean distance: (not calculated yet)
Cross-listing: Neurotree
Parents
Sign in to add mentorHarry Ischiropoulos | grad student | 2007 | Penn | |
(Catechol oxidation and alpha-synuclein aggregation: Implications for selective dopaminergic neurodegeneration in Parkinson's disease.) |
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Publications
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Shtilbans A, Esneault E, Simon F, et al. (2025) Evaluation of Additive Neuroprotective Effect of Combination Therapy for Parkinson's Disease Using In Vitro Models. Antioxidants (Basel, Switzerland). 14 |
Sokratian A, Zhou Y, Tatli M, et al. (2024) Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases. Science Advances. 10: eadq3539 |
Belur NR, Bustos BI, Lubbe SJ, et al. (2024) Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson's disease and dementia with Lewy bodies. Neuron |
Zalon AJ, Quiriconi DJ, Pitcairn C, et al. (2024) α-Synuclein: Multiple pathogenic roles in trafficking and proteostasis pathways in Parkinson's disease. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10738584241232963 |
Fagen SJ, Burgess JD, Lim MJ, et al. (2023) Honokiol decreases alpha-synuclein mRNA levels and reveals novel targets for modulating alpha-synuclein expression. Frontiers in Aging Neuroscience. 15: 1179086 |
Drobny A, Boros FA, Balta D, et al. (2023) Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models. Translational Neurodegeneration. 12: 31 |
Pitcairn C, Murata N, Zalon A, et al. (2023) Impaired autophagic-lysosomal fusion in Parkinson's patient midbrain neurons occurs through loss of ykt6 and is rescued by farnesyltransferase inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
Prieto Huarcaya S, Drobny A, Marques ARA, et al. (2022) Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models. Autophagy |
Francelle L, Mazzulli JR. (2022) Neuroinflammation in Gaucher disease, neuronal ceroid lipofuscinosis, and commonalities with Parkinson's disease. Brain Research. 1780: 147798 |
Fredriksen K, Aivazidis S, Sharma K, et al. (2021) Pathological α-syn aggregation is mediated by glycosphingolipid chain length and the physiological state of α-syn in vivo. Proceedings of the National Academy of Sciences of the United States of America. 118 |