Shen Shen, Ph.D.
Affiliations: | 2013 | Biochemistry and Biophysics | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
General Biophysics, Biochemistry, Virology BiologyGoogle:
"Shen Shen"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Aravind Asokan | grad student | 2013 | UNC Chapel Hill | |
| (Understanding and manipulating AAV-glycan interactions.) | ||||
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Publications
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| Asokan A, Shen S. (2023) Redirecting AAV vectors to extrahepatic tissues. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Maeder ML, Stefanidakis M, Wilson CJ, et al. (2019) Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10. Nature Medicine |
| Shen S, Sanchez ME, Blomenkamp K, et al. (2018) Amelioration of Alpha-1 Antitrypsin Deficiency Diseases with Genome Editing in Transgenic Mice. Human Gene Therapy |
| Friedland AE, Baral R, Singhal P, et al. (2015) Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications. Genome Biology. 16: 257 |
| Gori JL, Hsu PD, Maeder ML, et al. (2015) Delivery and Specificity of CRISPR-Cas9 Genome Editing Technologies for Human Gene Therapy. Human Gene Therapy. 26: 443-51 |
| Shen S, Berry GE, Castellanos Rivera RM, et al. (2015) Functional analysis of the putative integrin recognition motif on adeno-associated virus 9. The Journal of Biological Chemistry. 290: 1496-504 |
| Maeder ML, Shen S, Burnight ER, et al. (2015) 687. Therapeutic Correction of an LCA-Causing Splice Defect in the CEP290 Gene by CRISPR/Cas-Mediated Genome Editing Molecular Therapy. 23: S273-S274 |
| Shen S, Troupes AN, Pulicherla N, et al. (2013) Multiple roles for sialylated glycans in determining the cardiopulmonary tropism of adeno-associated virus 4. Journal of Virology. 87: 13206-13 |
| Shen S, Horowitz ED, Troupes AN, et al. (2013) Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiency. The Journal of Biological Chemistry. 288: 28814-23 |
| Shen S, Bryant KD, Sun J, et al. (2012) Glycan binding avidity determines the systemic fate of adeno-associated virus type 9. Journal of Virology. 86: 10408-17 |