Ismail M. Hafez, Ph.D.

Affiliations: 
2000 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
General Biophysics
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"Ismail Hafez"
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Parents

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Pietr R. Cullis grad student 2000 UBC
 (Lipid polymorphism and intracellular delivery.)
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Publications

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Leung AK, Tam YY, Chen S, et al. (2015) Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems. The Journal of Physical Chemistry. B. 119: 8698-706
Wang S(, Hafez IM, Wang J, et al. (2014) Optimizing Drug Release: Bilayer to Inverted Hexagonal Phase Transition of Cationic XTC2 and Anionic DSPS Lipid System is Influenced by pH, Temperature, and Salt Concentration Biophysical Journal. 106: 700a
Degtyar V, Hafez IM, Bray C, et al. (2013) Dance of the SNAREs: assembly and rearrangements detected with FRET at neuronal synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5507-23
Lin PJ, Tam YY, Hafez I, et al. (2013) Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 233-46
Leung AK, Hafez IM, Baoukina S, et al. (2012) Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core. The Journal of Physical Chemistry. C, Nanomaterials and Interfaces. 116: 18440-18450
Jayaraman M, Ansell SM, Mui BL, et al. (2012) Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo Angewandte Chemie - International Edition. 51: 8529-8533
Zhigaltsev IV, Belliveau N, Hafez I, et al. (2012) Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfluidic mixing. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 3633-40
Leung AKK, Hafez IM, Baoukina S, et al. (2012) Correction to “Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core” The Journal of Physical Chemistry C. 116: 22104-22104
Basha G, Novobrantseva TI, Rosin N, et al. (2011) Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells Molecular Therapy. 19: 2186-2200
Geetha-Loganathan P, Nimmagadda S, Hafez I, et al. (2011) Development of high-concentration lipoplexes for in vivo gene function studies in vertebrate embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 2108-19
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