Jerome Cluzeau, Ph.D.
Affiliations: | 2004 | Université de Montréal, Montréal, Canada |
Area:
Organic ChemistryGoogle:
"Jerome Cluzeau"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| William D. Lubell | grad student | 2004 | Université de Montréal | |
| (Developpement de methodes de synthese pour les acides amines indolizidin-9-ones substitues et utilisation des acides amines azabicycloalcanes en tant que mimes peptidiques.) | ||||
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Publications
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| Smilovic IG, Cluzeau J, Richter F, et al. (2018) Synthesis of enantiopure antiobesity drug lorcaserin. Bioorganic & Medicinal Chemistry |
| Cluzeau J, Stavber G. (2017) Development and optimization of a new synthetic process for lorcaserin. Bioorganic & Medicinal Chemistry |
| Troiani V, Cluzeau J, Časar Z. (2011) Application of chemoselective pancreatin powder-catalyzed deacetylation reaction in the synthesis of key statin side chain intermediate (4 R,6 S)-4-(tert-butyldimethylsilyloxy)-6-(hydroxymethyl)tetrahydropyran-2-one Organic Process Research and Development. 15: 622-630 |
| Suzuki Y, Cluzeau J, Hara T, et al. (2008) Structure-activity relationships of pyrazine-based CK2 inhibitors: synthesis and evaluation of 2,6-disubstituted pyrazines and 4,6-disubstituted pyrimidines. Archiv Der Pharmazie. 341: 554-61 |
| Tomita K, Oishi S, Cluzeau J, et al. (2007) SAR and QSAR studies on the N-terminally acylated pentapeptide agonists for GPR54. Journal of Medicinal Chemistry. 50: 3222-8 |
| Cluzeau J, Oishi S, Ohno H, et al. (2007) Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists. Organic & Biomolecular Chemistry. 5: 1915-23 |
| Boeglin D, Hamdan FF, Melendez RE, et al. (2007) Calcitonin gene-related peptide analogues with aza and indolizidinone amino acid residues reveal conformational requirements for antagonist activity at the human calcitonin gene-related peptide 1 receptor. Journal of Medicinal Chemistry. 50: 1401-8 |
| Ueda S, Oishi S, Wang ZX, et al. (2007) Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: disclosing the importance of side-chain and backbone functionalities. Journal of Medicinal Chemistry. 50: 192-8 |
| Tomita K, Niida A, Oishi S, et al. (2006) Structure-activity relationship study on small peptidic GPR54 agonists. Bioorganic & Medicinal Chemistry. 14: 7595-603 |
| Cluzeau J, Lubell WD. (2005) Design, synthesis, and application of azabicyclo[X.Y.0]alkanone amino acids as constrained dipeptide surrogates and peptide mimics. Biopolymers. 80: 98-150 |