Melinda D. Willard, Ph.D.

Affiliations: 
2006 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacology
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David P. Siderovski grad student 2006 UNC Chapel Hill
 (Multiple domain 'nexus' proteins in receptor-mediated cell signaling.)
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Publications

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Schroer AB, Mohamed JS, Willard MD, et al. (2019) A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation. Plos One. 14: e0216167
Esseltine JL, Willard MD, Wulur IH, et al. (2013) Somatic mutations in GRM1 in cancer alter metabotropic glutamate receptor 1 intracellular localization and signaling. Molecular Pharmacology. 83: 770-80
Willard MD, Lajiness ME, Wulur IH, et al. (2012) Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes. Molecular Cancer Research : McR. 10: 739-49
Bosch DE, Willard FS, Ramanujam R, et al. (2012) A P-loop mutation in Gα subunits prevents transition to the active state: implications for G-protein signaling in fungal pathogenesis. Plos Pathogens. 8: e1002553
Willard FS, Willard MD, Kimple AJ, et al. (2009) Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector. Plos One. 4: e4884
Johnston CA, Willard MD, Kimple AJ, et al. (2008) A sweet cycle for Arabidopsis G-proteins: Recent discoveries and controversies in plant G-protein signal transduction. Plant Signaling & Behavior. 3: 1067-76
Willard FS, Zheng Z, Guo J, et al. (2008) A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics. The Journal of Biological Chemistry. 283: 36698-710
Willard MD, Willard FS, Li X, et al. (2007) Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation. The Embo Journal. 26: 2029-40
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