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Ira S. Winer, Ph.D.

Affiliations: 
2005 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Molecular Biology, Immunology
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Eric R. Fearon grad student 2005 University of Michigan
 (Analysis of beta-catenin's amino-terminal domain and ITF -2, a beta-catenin/TCF-regulated gene, in neoplastic transformation.)

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Feng Y, Bommer GT, Zhai Y, et al. (2007) Drosophila split ends homologue SHARP functions as a positive regulator of Wnt/beta-catenin/T-cell factor signaling in neoplastic transformation. Cancer Research. 67: 482-91
Winer IS, Bommer GT, Gonik N, et al. (2006) Lysine residues Lys-19 and Lys-49 of beta-catenin regulate its levels and function in T cell factor transcriptional activation and neoplastic transformation. The Journal of Biological Chemistry. 281: 26181-7
Kolligs FT, Nieman MT, Winer I, et al. (2002) ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation. Cancer Cell. 1: 145-55
Paul CP, Good PD, Winer I, et al. (2002) Effective expression of small interfering RNA in human cells. Nature Biotechnology. 20: 505-8
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