Fenfei Leng
Affiliations: | Florida International University, Miami, FL, United States |
Area:
Medical BiophysicsGoogle:
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Publications
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| Deng Z, Chapagain P, Leng F. (2023) Macromolecular Crowding Potently Stimulates DNA Supercoiling Activity of Mycobacterium tuberculosis DNA Gyrase. The Journal of Biological Chemistry. 105439 |
| Dias M, Chapagain T, Leng F. (2023) A Fluorescence-Based, T5 Exonuclease-Amplified DNA Cleavage Assay for Discovering Bacterial DNA Gyrase Poisons. Biorxiv : the Preprint Server For Biology |
| Tantak M, Rayala R, Deng Z, et al. (2023) Polyheterocyclic peptidomimetics: Parallel solid phase synthesis of oligo cyclic guanidines and their inhibition activity against Mycobacterium tuberculosis DNA gyrase. Bioorganic & Medicinal Chemistry Letters. 93: 129439 |
| Alfonso EE, Deng Z, Boaretto D, et al. (2022) Novel and Structurally Diversified Bacterial DNA Gyrase Inhibitors Discovered through a Fluorescence-Based High-Throughput Screening Assay. Acs Pharmacology & Translational Science. 5: 932-944 |
| Alfonso EE, Troche R, Deng Z, et al. (2022) Potent Inhibition of Bacterial DNA Gyrase by Digallic Acid and Other Gallate Derivatives. Chemmedchem. e202200301 |
| Sipe SN, Jeanne Dit Fouque K, Garabedian A, et al. (2022) Exploring the Conformations and Binding Location of HMGA2·DNA Complexes Using Ion Mobility Spectrometry and 193 nm Ultraviolet Photodissociation Mass Spectrometry. Journal of the American Society For Mass Spectrometry |
| Jeanne Dit Fouque K, Sipe SN, Garabedian A, et al. (2022) Exploring the Conformational and Binding Dynamics of HMGA2·DNA Complexes Using Trapped Ion Mobility Spectrometry-Mass Spectrometry. Journal of the American Society For Mass Spectrometry |
| Garabedian A, Jeanne Dit Fouque K, Chapagain PP, et al. (2022) AT-hook peptides bind the major and minor groove of AT-rich DNA duplexes. Nucleic Acids Research. 50: 2431-2439 |
| Yan Y, Xu W, Kumar S, et al. (2021) Negative DNA supercoiling makes protein-mediated looping deterministic and ergodic within the bacterial doubling time. Nucleic Acids Research |
| Deng Z, Leng F. (2021) A T5 Exonuclease-Based Assay for DNA Topoisomerases and DNA Intercalators. Acs Omega. 6: 12205-12212 |