Elena Avdievich, Ph.D.

Affiliations: 
2006 Yeshiva University, New York, NY, United States 
Area:
Molecular Biology
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"Elena Avdievich"

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Winfried Edelmann grad student 2006 Yeshiva University
 (Role of mismatch repair proteins in genomic stability, cancer and meiosis.)
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Publications

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Chen CC, Avdievich E, Zhang Y, et al. (2017) EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells. Dna Repair. 57: 98-106
Schaetzlein S, Chahwan R, Avdievich E, et al. (2013) Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes. Proceedings of the National Academy of Sciences of the United States of America. 110: E2470-9
Chahwan R, van Oers JM, Avdievich E, et al. (2012) The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination. The Journal of Experimental Medicine. 209: 671-8
Roa S, Avdievich E, Peled JU, et al. (2008) Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression. Proceedings of the National Academy of Sciences of the United States of America. 105: 16248-53
Marinovic-Terzic I, Yoshioka-Yamashita A, Shimodaira H, et al. (2008) Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q Proceedings of the National Academy of Sciences of the United States of America. 105: 13993-13998
Avdievich E, Reiss C, Scherer SJ, et al. (2008) Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 4247-52
Kan R, Sun X, Kolas NK, et al. (2008) Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathway. Biology of Reproduction. 78: 462-71
Scherer SJ, Avdievich E, Edelmann W. (2005) Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition. Biochemical Society Transactions. 33: 689-93
Lin DP, Wang Y, Scherer SJ, et al. (2004) An Msh2 point mutation uncouples DNA mismatch repair and apoptosis. Cancer Research. 64: 517-22
Wong E, Yang K, Kuraguchi M, et al. (2002) Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation. Proceedings of the National Academy of Sciences of the United States of America. 99: 14937-42
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