Patrick C. Bradshaw, PhD

Affiliations: 
2015-pres Department of Biomedical Sciences East Tennessee State University - Quillen School of Medicine 
Area:
mitochondrial function, aging, neurodegeneration
Website:
http://www.etsu.edu/com/dbms/faculty/bios/bradshaw.aspx
Google:
"Patrick Bradshaw"
Bio:

Dr. Bradshaw grew up in East Peoria, IL, attended the University of Illinois for his B.S. degree, majoring in bioengineering and chemistry. He went on to earn a PhD in biochemistry at Ohio State University followed by postdoctoral research at the University of Missouri-Columbia, Virginia Tech, and the University of Wisconsin Madison. He was a faculty member at the University of South Florida from 2008-2015.

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Publications

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Delic V, Griffin JWD, Zivkovic S, et al. (2017) Individual Amino Acid Supplementation Can Improve Energy Metabolism and Decrease ROS Production in Neuronal Cells Overexpressing Alpha-Synuclein. Neuromolecular Medicine
Sawmiller D, Li S, Mori T, et al. (2017) Beneficial effects of a pyrroloquinolinequinone-containing dietary formulation on motor deficiency, cognitive decline and mitochondrial dysfunction in a mouse model of Alzheimer's disease. Heliyon. 3: e00279
Griffin JW, Bradshaw PC. (2017) Amino Acid Catabolism in Alzheimer's Disease Brain: Friend or Foe? Oxidative Medicine and Cellular Longevity. 2017: 5472792
Copes N, Edwards C, Chaput D, et al. (2015) Metabolome and proteome changes with aging in Caenorhabditis elegans. Experimental Gerontology. 72: 67-84
O'Neal-Moffitt G, Delic V, Bradshaw PC, et al. (2015) Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPP(swe)/PS1 mice. Molecular Neurodegeneration. 10: 27
Delic V, Brownlow M, Joly-Amado A, et al. (2015) Calorie restriction does not restore brain mitochondrial function in P301L tau mice, but it does decrease mitochondrial F0F1-ATPase activity. Molecular and Cellular Neurosciences. 67: 46-54
Edwards C, Copes N, Bradshaw PC. (2015) D-ß-hydroxybutyrate: an anti-aging ketone body. Oncotarget. 6: 3477-8
Edwards C, Canfield J, Copes N, et al. (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. Bmc Genetics. 16: 8
Edwards C, Canfield J, Copes N, et al. (2014) D-beta-hydroxybutyrate extends lifespan in C. elegans. Aging. 6: 621-44
Bradshaw PC, Pfeiffer DR. (2013) Characterization of the respiration-induced yeast mitochondrial permeability transition pore. Yeast (Chichester, England). 30: 471-83
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