Shane William Krska
Affiliations: | Merck Research Laboratories, Boston, MA, United States |
Area:
catalysis, high-throughput experimentation, process research, medicinal chemistryGoogle:
"Shane Krska"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Dietmar Seyferth | grad student | 1992-1997 | MIT |
| Robert G. Bergman | post-doc | 1997-1999 | UC Berkeley |
Collaborators
Sign in to add collaborator| Stephen L. Buchwald | collaborator | ||
| Paul J. Chirik | collaborator | ||
| Matthew B. Francis | collaborator | ||
| John T. Groves | collaborator | ||
| Kendall N. Houk | collaborator | ||
| Guy Lloyd-Jones | collaborator | ||
| Robert E. Maleczka | collaborator | ||
| Melanie Sarah Sanford | collaborator | ||
| Milton R. "Mitch" Smith III | collaborator | ||
| Shannon S. Stahl | collaborator | ||
| Barry M. Trost | collaborator | ||
| Xumu Zhang | collaborator |
BETA: Related publications
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Publications
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| Chen SJ, Krska SW, Stahl SS. (2023) Copper-Catalyzed Benzylic C-H Cross-Coupling Enabled by Redox Buffers: Expanding Synthetic Access to Three-Dimensional Chemical Space. Accounts of Chemical Research. 56: 3604-3615 |
| Maity S, Lopez MA, Bates DM, et al. (2023) Polar Heterobenzylic C(sp)-H Chlorination Pathway Enabling Efficient Diversification of Aromatic Nitrogen Heterocycles. Journal of the American Chemical Society |
| Cao W, Maza JC, Chernyak N, et al. (2023) Modification of Cysteine-Substituted Antibodies Using Enzymatic Oxidative Coupling Reactions. Bioconjugate Chemistry |
| King RP, Krska SW, Buchwald SL. (2021) A Neophyl Palladacycle as an Air- and Thermally Stable Precursor to Oxidative Addition Complexes. Organic Letters |
| Chen SJ, Golden DL, Krska SW, et al. (2021) Copper-Catalyzed Cross-Coupling of Benzylic C-H Bonds and Azoles with Controlled -Site Selectivity. Journal of the American Chemical Society |
| Suh SE, Nkulu LE, Lin S, et al. (2021) Benzylic C-H isocyanation/amine coupling sequence enabling high-throughput synthesis of pharmaceutically relevant ureas. Chemical Science. 12: 10380-10387 |
| King RP, Krska SW, Buchwald SL. (2021) A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes. Organic Letters |
| Vasilopoulos A, Krska SW, Stahl SS. (2021) C(sp)-H methylation enabled by peroxide photosensitization and Ni-mediated radical coupling. Science (New York, N.Y.). 372: 398-403 |
| Hansen KB, Hsiao Y, Xu F, et al. (2020) Correction to "Highly Efficient Asymmetric Synthesis of Sitagliptin". Journal of the American Chemical Society |
| Hu H, Chen SJ, Mandal M, et al. (2020) Copper-catalysed benzylic C-H coupling with alcohols via radical relay enabled by redox buffering. Nature Catalysis. 3: 358-367 |