Jennie Larkin - Publications

Affiliations: 
NHLBI, Bethesda, MD, United States 
Area:
systems biology

8/434 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2004 Barakat MT, O'Hara BF, Cao VH, Larkin JE, Heller HC, Ruby NF. Light pulses do not induce c-fos or per1 in the SCN of hamsters that fail to reentrain to the photocycle. Journal of Biological Rhythms. 19: 287-97. PMID 15245648 DOI: 10.1177/0748730404266771  0.572
2004 Larkin JE, Yokogawa T, Heller HC, Franken P, Ruby NF. Homeostatic regulation of sleep in arrhythmic Siberian hamsters. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 287: R104-11. PMID 14962826 DOI: 10.1152/Ajpregu.00676.2003  0.556
2003 Bae HH, Larkin JE, Zucker I. Juvenile Siberian hamsters display torpor and modified locomotor activity and body temperature rhythms in response to reduced food availability. Physiological and Biochemical Zoology : Pbz. 76: 858-67. PMID 14988801 DOI: 10.1086/381462  0.515
2003 Larkin JE, Yellon SM, Zucker I. Melatonin production accompanies arousal from daily torpor in Siberian hamsters. Physiological and Biochemical Zoology : Pbz. 76: 577-85. PMID 13130436 DOI: 10.1086/375436  0.415
2002 Freeman DA, Larkin JE, Seliby L. Testicular and somatic growth in Siberian hamsters depend on the melatonin-free interval between twice daily melatonin signals. Journal of Neuroendocrinology. 14: 228-33. PMID 11999723 DOI: 10.1046/j.0007-1331.2001.00767.x  0.509
2002 Larkin JE, Jones J, Zucker I. Temperature dependence of gonadal regression in Syrian hamsters exposed to short day lengths. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 282: R744-52. PMID 11832395 DOI: 10.1152/Ajpregu.00299.2001  0.462
2001 Larkin JE, Freeman DA, Zucker I. Low ambient temperature accelerates short-day responses in Siberian hamsters by altering responsiveness to melatonin. Journal of Biological Rhythms. 16: 76-86. PMID 11220782 DOI: 10.1177/074873040101600109  0.575
1998 Larkin JE, Heller CH. The disappearing slow wave activity of hibernators. Sleep Research Online : Sro. 1: 96-101. PMID 11382864  0.428
Low-probability matches (unlikely to be authored by this person)
1996 Larkin JE, Heller HC. Temperature sensitivity of sleep homeostasis during hibernation in the golden-mantled ground squirrel. The American Journal of Physiology. 270: R777-84. PMID 8967407 DOI: 10.1152/AJPREGU.1996.270.4.R777  0.218
2002 Larkin JE, Franken P, Heller HC. Loss of circadian organization of sleep and wakefulness during hibernation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 282: R1086-95. PMID 11893613 DOI: 10.1152/Ajpregu.00771.2000  0.218
1999 Larkin JE, Heller HC. Sleep after arousal from hibernation is not homeostatically regulated. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 276: R522-R529. PMID 29591477 DOI: 10.1152/ajpregu.1999.276.2.R522  0.204
1999 Larkin JE, Heller HC. Sleep after arousal from hibernation is not homeostatically regulated. The American Journal of Physiology. 276: R522-9. PMID 9950933  0.204
1996 Grahn DA, Heller MC, Larkin JE, Heller HC. Appropriate thermal manipulations eliminate tremors in rats recovering from halothane anesthesia. Journal of Applied Physiology (Bethesda, Md. : 1985). 81: 2547-54. PMID 9018505 DOI: 10.1152/JAPPL.1996.81.6.2547  0.159
2007 Larkin JM, Hughes SA, Beirne DA, Patel PM, Gibbens IM, Bate SC, Thomas K, Eisen TG, Gore ME. A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma. British Journal of Cancer. 96: 44-8. PMID 17146474 DOI: 10.1038/sj.bjc.6603503  0.138
2015 Skinner GE, Fleischman GJ, Balster F, Reineke K, Reddy NR, Larkin JW. Effect of Fill Temperature on Clostridium botulinum Type A Toxin Activity during the Hot Filling of Juice Bottles. Journal of Food Protection. 78: 1506-11. PMID 26219364 DOI: 10.4315/0362-028X.JFP-14-378  0.126
2015 Turajlic S, Larkin J, Swanton C. Academically led clinical trials: challenges and opportunities. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 26: 2010-1. PMID 26240217 DOI: 10.1093/Annonc/Mdv332  0.115
2015 Melemenidis S, Jefferson A, Ruparelia N, Akhtar AM, Xie J, Allen D, Hamilton A, Larkin JR, Perez-Balderas F, Smart SC, Muschel RJ, Chen X, Sibson NR, Choudhury RP. Molecular magnetic resonance imaging of angiogenesis in vivo using polyvalent cyclic RGD-iron oxide microparticle conjugates. Theranostics. 5: 515-29. PMID 25767618 DOI: 10.7150/Thno.10319  0.114
2014 Larkin J, Fishman M, Wood L, Negrier S, Olivier K, Pyle L, Gorbunova V, Jonasch E, Andrews L, Staehler M. Axitinib for the treatment of metastatic renal cell carcinoma: recommendations for therapy management to optimize outcomes. American Journal of Clinical Oncology. 37: 397-403. PMID 23357974 DOI: 10.1097/COC.0b013e31827b45f9  0.107
2011 De Veylder L, Larkin JC, Schnittger A. Molecular control and function of endoreplication in development and physiology. Trends in Plant Science. 16: 624-34. PMID 21889902 DOI: 10.1016/j.tplants.2011.07.001  0.104
2014 Ingraham P, Marley MS, Saumon D, Marois C, Macintosh B, Barman T, Bauman B, Burrows A, Chilcote JK, De Rosa RJ, Dillon D, Doyon R, Dunn J, Erikson D, Fitzgerald MP, ... ... Larkin JA, et al. Gemini planet imager spectroscopy of the HR 8799 planets c and d Astrophysical Journal Letters. 794. DOI: 10.1088/2041-8205/794/1/L15  0.103
2015 Hamdoun S, Zhang C, Gill M, Kumar N, Churchman ML, Larkin JC, Kwon A, Lu H. Differential Roles of Two Homologous Cyclin-Dependent Kinase Inhibitor Genes in Regulating Cell Cycle and Innate Immunity in Arabidopsis. Plant Physiology. PMID 26561564 DOI: 10.1104/pp.15.01466  0.103
2011 Anderson NM, Larkin JW, Cole MB, Skinner GE, Whiting RC, Gorris LG, Rodriguez A, Buchanan R, Stewart CM, Hanlin JH, Keener L, Hall PA. Food safety objective approach for controlling Clostridium botulinum growth and toxin production in commercially sterile foods. Journal of Food Protection. 74: 1956-89. PMID 22054200 DOI: 10.4315/0362-028X.JFP-11-082  0.103
2011 Suwaki N, Vanhecke E, Atkins KM, Graf M, Swabey K, Huang P, Schraml P, Moch H, Cassidy AM, Brewer D, Al-Lazikani B, Workman P, De-Bono J, Kaye SB, Larkin J, et al. A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma. Science Translational Medicine. 3: 85ra47. PMID 21632985 DOI: 10.1126/scitranslmed.3002004  0.101
2015 Larkin J. The auto industry's newest concern: Cyberproofing the modern-day connected car Automotive Industries Ai. 195.  0.101
2015 Biondo A, Alexander H, Khabra K, Pickering L, Gore M, Larkin J. Pazopanib-induced alopecia, an underestimated toxicity? Frontiers in Oncology. 5: 112. PMID 26029668 DOI: 10.3389/fonc.2015.00112  0.099
2014 MacIntosh BA, Anthony A, Atwood J, Bauman B, Cardwell A, Caputa K, Chilcote J, De Rosa RJ, Dillon D, Doyon R, Dunn J, Erickson D, Fitzgerald MP, Gavel DT, Galvez R, ... Larkin J, et al. The Gemini planet imager: First light and commissioning Proceedings of Spie - the International Society For Optical Engineering. 9148. DOI: 10.1117/12.2056709  0.099
2008 Keller SE, Shazer AG, Fleischman GJ, Chirtel S, Anderson N, Larkin J. Modification of the submerged coil to prevent microbial carryover error in thermal death studies. Journal of Food Protection. 71: 775-80. PMID 18468032  0.098
2008 Larkin JO, Casey GD, Tangney M, Cashman J, Collins CG, Soden DM, O'Sullivan GC. Effective tumor treatment using optimized ultrasound-mediated delivery of bleomycin. Ultrasound in Medicine & Biology. 34: 406-13. PMID 17988788 DOI: 10.1016/j.ultrasmedbio.2007.09.005  0.097
2015 Perrin MD, Duchene G, Millar-Blanchaer M, Fitzgerald MP, Graham JR, Wiktorowicz SJ, Kalas PG, Macintosh B, Bauman B, Cardwell A, Chilcote J, De Rosa RJ, Dillon D, Doyon R, Dunn J, ... Larkin JE, et al. Polarimetry with the gemini planet imager: Methods, performance at first light, and the circumstellar ring around HR 4796A Astrophysical Journal. 799. DOI: 10.1088/0004-637X/799/2/182  0.097
2015 Seifert H, Fisher R, Martin-Liberal J, Edmonds K, Hughes P, Khabra K, Gore M, Larkin J. Prognostic markers and tumour growth kinetics in melanoma patients progressing on vemurafenib. Melanoma Research. PMID 26684061 DOI: 10.1097/CMR.0000000000000218  0.096
2013 Khattak MA, Bakr F, Krzystanek M, Szallasi Z, Gerlinger M, Santos C, Swanton C, Pickering LM, Gore ME, Larkin JM. Prognostic and predictive markers in metastatic renal cell carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 971-2. PMID 23295806 DOI: 10.1200/Jco.2012.46.9353  0.095
2006 Walsh M, Tangney M, O'Neill MJ, Larkin JO, Soden DM, McKenna SL, Darcy R, O'Sullivan GC, O'Driscoll CM. Evaluation of cellular uptake and gene transfer efficiency of pegylated poly-L-lysine compacted DNA: implications for cancer gene therapy. Molecular Pharmaceutics. 3: 644-53. PMID 17140252 DOI: 10.1021/mp0600034  0.095
2011 Okera M, Chan S, Dernede U, Larkin J, Popat S, Gilbert D, Jones L, Osuji N, Sykes H, Oakley C, Pickering L, Lofts F, Chowdhury S. A prospective study of chemotherapy-induced febrile neutropenia in the South West London Cancer Network. Interpretation of study results in light of NCAG/NCEPOD findings. British Journal of Cancer. 104: 407-12. PMID 21179036 DOI: 10.1038/sj.bjc.6606059  0.095
2013 Boves TJ, Buehler DA, Sheehan J, Wood PB, Rodewald AD, Larkin JL, Keyser PD, Newell FL, George GA, Bakermans MH, Evans A, Beachy TA, McDermott ME, Perkins KA, White M, et al. Emulating natural disturbances for declining late-successional species: a case study of the consequences for cerulean warblers (Setophaga cerulea). Plos One. 8: e52107. PMID 23308104 DOI: 10.1371/Journal.Pone.0052107  0.095
2013 Moriarity AR, Larkin JO, O'Sullivan KE, Ravi N, Reynolds JV. Spontaneous perforation of the esophagus in a patient with achalasia. The Annals of Thoracic Surgery. 96: 1456-7. PMID 24088458 DOI: 10.1016/j.athoracsur.2013.01.091  0.095
2012 Pacey S, Gore M, Chao D, Banerji U, Larkin J, Sarker S, Owen K, Asad Y, Raynaud F, Walton M, Judson I, Workman P, Eisen T. A Phase II trial of 17-allylamino, 17-demethoxygeldanamycin (17-AAG, tanespimycin) in patients with metastatic melanoma. Investigational New Drugs. 30: 341-9. PMID 20683637 DOI: 10.1007/s10637-010-9493-4  0.095
2014 Whelan MC, Casey G, Larkin JO, Guinn BA, O'Sullivan GC, Tangney M. Oral tolerance to cancer can be abrogated by T regulatory cell inhibition. Plos One. 9: e97602. PMID 24832130 DOI: 10.1371/journal.pone.0097602  0.094
2012 Papantonis A, Kohro T, Baboo S, Larkin JD, Deng B, Short P, Tsutsumi S, Taylor S, Kanki Y, Kobayashi M, Li G, Poh HM, Ruan X, Aburatani H, Ruan Y, et al. TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed. The Embo Journal. 31: 4404-14. PMID 23103767 DOI: 10.1038/Emboj.2012.288  0.094
2015 S Ahmad S, Qian W, Ellis S, Mason E, Khattak MA, Gupta A, Shaw H, Quinton A, Kovarikova J, Thillai K, Rao A, Board R, Nobes J, Dalgleish A, Grumett S, ... ... Larkin J, et al. Ipilimumab in the real world: the UK expanded access programme experience in previously treated advanced melanoma patients. Melanoma Research. 25: 432-42. PMID 26225580 DOI: 10.1097/CMR.0000000000000185  0.093
2007 Peres A, Churchman ML, Hariharan S, Himanen K, Verkest A, Vandepoele K, Magyar Z, Hatzfeld Y, Van Der Schueren E, Beemster GT, Frankard V, Larkin JC, Inzé D, De Veylder L. Novel plant-specific cyclin-dependent kinase inhibitors induced by biotic and abiotic stresses. The Journal of Biological Chemistry. 282: 25588-96. PMID 17599908 DOI: 10.1074/jbc.M703326200  0.093
2006 Churchman ML, Brown ML, Kato N, Kirik V, Hülskamp M, Inzé D, De Veylder L, Walker JD, Zheng Z, Oppenheimer DG, Gwin T, Churchman J, Larkin JC. SIAMESE, a plant-specific cell cycle regulator, controls endoreplication onset in Arabidopsis thaliana. The Plant Cell. 18: 3145-57. PMID 17098811 DOI: 10.1105/Tpc.106.044834  0.093
2015 Larkin J, Lao CD, Urba WJ, McDermott DF, Horak C, Jiang J, Wolchok JD. Efficacy and Safety of Nivolumab in Patients With BRAF V600 Mutant and BRAF Wild-Type Advanced Melanoma: A Pooled Analysis of 4 Clinical Trials. Jama Oncology. 1: 433-40. PMID 26181250 DOI: 10.1001/Jamaoncol.2015.1184  0.093
2010 Casey G, Cashman JP, Morrissey D, Whelan MC, Larkin JO, Soden DM, Tangney M, O'Sullivan GC. Sonoporation mediated immunogene therapy of solid tumors. Ultrasound in Medicine & Biology. 36: 430-40. PMID 20133039 DOI: 10.1016/j.ultrasmedbio.2009.11.005  0.092
2014 Yi D, Alvim Kamei CL, Cools T, Vanderauwera S, Takahashi N, Okushima Y, Eekhout T, Yoshiyama KO, Larkin J, Van den Daele H, Conklin P, Britt A, Umeda M, De Veylder L. The Arabidopsis SIAMESE-RELATED cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species. The Plant Cell. 26: 296-309. PMID 24399300 DOI: 10.1105/tpc.113.118943  0.092
2015 Hirata E, Girotti MR, Viros A, Hooper S, Spencer-Dene B, Matsuda M, Larkin J, Marais R, Sahai E. Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling. Cancer Cell. 27: 574-88. PMID 25873177 DOI: 10.1016/j.ccell.2015.03.008  0.092
2010 Goldstein R, Pickering L, Larkin J. Does axitinib (AG-01376) have a future role in metastatic renal cell carcinoma and other malignancies? Expert Review of Anticancer Therapy. 10: 1545-57. PMID 20942625 DOI: 10.1586/era.10.134  0.091
2008 Cashman JP, Larkin JO, Casey G, Whelan MC, Collins C, Aarons S, Tangney M, O'Sullivan GC. Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers. Cancer Letters. 262: 94-102. PMID 18179863 DOI: 10.1016/j.canlet.2007.11.042  0.091
2014 Chen S, Meyer E, Wright SA, Moore AM, Larkin JE, Maire J, Mieda E, Simard L. The infrared imaging spectrograph (IRIS) for TMT: Volume phase holographic grating performance testing and discussion Proceedings of Spie - the International Society For Optical Engineering. 9147. DOI: 10.1117/12.2055609  0.09
2015 He C, Yu CR, Sun L, Mahdi RM, Larkin J, Egwuagu CE. Topical administration of a suppressor of cytokine signaling-1 (SOCS1) mimetic peptide inhibits ocular inflammation and mitigates ocular pathology during mouse uveitis. Journal of Autoimmunity. PMID 26094775 DOI: 10.1016/J.Jaut.2015.05.011  0.09
2006 Tangney M, Casey G, Larkin JO, Collins CG, Soden D, Cashman J, Whelan MC, O'Sullivan GC. Non-viral in vivo immune gene therapy of cancer: combined strategies for treatment of systemic disease. Cancer Immunology, Immunotherapy : Cii. 55: 1443-50. PMID 16612593 DOI: 10.1007/s00262-006-0169-z  0.089
2014 Larkin J, Chen B, Shi XH, Mishima T, Kokame K, Barak Y, Sadovsky Y. NDRG1 deficiency attenuates fetal growth and the intrauterine response to hypoxic injury. Endocrinology. 155: 1099-106. PMID 24424031 DOI: 10.1210/en.2013-1425  0.089
2015 Kumar N, Harashima H, Kalve S, Bramsiepe J, Wang K, Sizani BL, Bertrand LL, Johnson MC, Faulk C, Dale R, Simmons LA, Churchman ML, Sugimoto K, Kato N, Dasanayake M, ... Larkin JC, et al. Functional Conservation in the SIAMESE-RELATED Family of Cyclin-Dependent Kinase Inhibitors in Land Plants. The Plant Cell. PMID 26546445 DOI: 10.1105/Tpc.15.00489  0.089
2013 Khattak MA, Fisher R, Hughes P, Gore M, Larkin J. Ipilimumab activity in advanced uveal melanoma. Melanoma Research. 23: 79-81. PMID 23211837 DOI: 10.1097/CMR.0b013e32835b554f  0.089
2004 Larkin JE, Frank BC, Gaspard RM, Duka I, Gavras H, Quackenbush J. Cardiac transcriptional response to acute and chronic angiotensin II treatments. Physiological Genomics. 18: 152-66. PMID 15126644 DOI: 10.1152/Physiolgenomics.00057.2004  0.089
2012 Monk JP, Villalona-Calero M, Larkin J, Otterson G, Spriggs DS, Hannah AL, Cropp GF, Johnson RG, Hensley ML. A phase 1 study of KOS-862 (Epothilone D) co-administered with carboplatin (Paraplatin®) in patients with advanced solid tumors. Investigational New Drugs. 30: 1676-83. PMID 21826439 DOI: 10.1007/s10637-011-9731-4  0.088
2015 Seifert H, Hirata E, Gore M, Khabra K, Messiou C, Larkin J, Sahai E. Extrinsic factors can mediate resistance to BRAF inhibition in central nervous system melanoma metastases. Pigment Cell & Melanoma Research. PMID 26414886 DOI: 10.1111/pcmr.12424  0.088
2007 Larkin JM, Porter CD. Complement insufficiency limits efficacy in a xenograft model of hyperacute rejection for cancer therapy. Cancer Immunology, Immunotherapy : Cii. 56: 60-9. PMID 16715304 DOI: 10.1007/s00262-006-0174-2  0.088
2015 Gravis G, Chanez B, Derosa L, Beuselinck B, Barthelemy P, Laguerre B, Brachet PE, Joly F, Escudier B, Harrison DJ, Laird A, Vasudev N, Ralph C, Larkin J, Lote H, et al. Effect of glandular metastases on overall survival of patients with metastatic clear cell renal cell carcinoma in the antiangiogenic therapy era. Urologic Oncology. PMID 26670200 DOI: 10.1016/J.Urolonc.2015.10.015  0.087
2011 Larkin J, Swanton C, Pickering L. Optimizing treatment of metastatic renal cell carcinoma by changing mechanism of action. Expert Review of Anticancer Therapy. 11: 639-49. PMID 21504330 DOI: 10.1586/Era.11.21  0.087
2010 Kasili R, Walker JD, Simmons LA, Zhou J, De Veylder L, Larkin JC. SIAMESE cooperates with the CDH1-like protein CCS52A1 to establish endoreplication in Arabidopsis thaliana trichomes. Genetics. 185: 257-68. PMID 20194967 DOI: 10.1534/genetics.109.113274  0.087
2014 Molina AM, Hutson TE, Larkin J, Gold AM, Wood K, Carter D, Motzer R, Michaelson MD. A phase 1b clinical trial of the multi-targeted tyrosine kinase inhibitor lenvatinib (E7080) in combination with everolimus for treatment of metastatic renal cell carcinoma (RCC). Cancer Chemotherapy and Pharmacology. 73: 181-9. PMID 24190702 DOI: 10.1007/s00280-013-2339-y  0.086
2012 Gerlinger M, Santos CR, Spencer-Dene B, Martinez P, Endesfelder D, Burrell RA, Vetter M, Jiang M, Saunders RE, Kelly G, Dykema K, Rioux-Leclercq N, Stamp G, Patard JJ, Larkin J, et al. Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target. The Journal of Pathology. 227: 146-56. PMID 22362593 DOI: 10.1002/Path.4006  0.086
2014 Sanchez-Laorden B, Viros A, Girotti MR, Pedersen M, Saturno G, Zambon A, Niculescu-Duvaz D, Turajlic S, Hayes A, Gore M, Larkin J, Lorigan P, Cook M, Springer C, Marais R. BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling. Science Signaling. 7: ra30. PMID 24667377 DOI: 10.1126/scisignal.2004815  0.086
2014 Antonia SJ, Larkin J, Ascierto PA. Immuno-oncology combinations: a review of clinical experience and future prospects. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 6258-68. PMID 25341541 DOI: 10.1158/1078-0432.CCR-14-1457  0.086
2015 Schill KM, Wang Y, Butler RR, Pombert JF, Reddy NR, Skinner GE, Larkin JW. Comparative analysis of Clostridium sporogenes PA 3679 isolates obtained from different sources using pulsed-field gel electrophoresis (PFGE) and high-throughput sequencing. Applied and Environmental Microbiology. PMID 26519392 DOI: 10.1128/AEM.02616-15  0.085
2004 Soden D, Larkin J, Collins C, Piggott J, Morrissey A, Norman A, Dunne C, O'Sullivan GC. The development of novel flexible electrode arrays for the electrochemotherapy of solid tumour tissue. (Potential for endoscopic treatment of inaccessible cancers). Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 5: 3547-50. PMID 17271056 DOI: 10.1109/IEMBS.2004.1403997  0.085
2010 Bramsiepe J, Wester K, Weinl C, Roodbarkelari F, Kasili R, Larkin JC, Hülskamp M, Schnittger A. Endoreplication controls cell fate maintenance. Plos Genetics. 6: e1000996. PMID 20585618 DOI: 10.1371/journal.pgen.1000996  0.084
2012 Kirkwood JM, Bastholt L, Robert C, Sosman J, Larkin J, Hersey P, Middleton M, Cantarini M, Zazulina V, Kemsley K, Dummer R. Phase II, open-label, randomized trial of the MEK1/2 inhibitor selumetinib as monotherapy versus temozolomide in patients with advanced melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 555-67. PMID 22048237 DOI: 10.1158/1078-0432.CCR-11-1491  0.084
2006 Larkin J, Bost A, Glass JI, Tan SL. Cytokine-activated natural killer cells exert direct killing of hepatoma cells harboring hepatitis C virus replicons. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 26: 854-65. PMID 17238828 DOI: 10.1089/jir.2006.26.854  0.084
2013 Ascierto PA, Grimaldi AM, Acquavella N, Borgognoni L, Calabrò L, Cascinelli N, Cesano A, Del Vecchio M, Eggermont AM, Faries M, Ferrone S, Fox BA, Gajewski TF, Galon J, Gnjatic S, ... ... Larkin J, et al. Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012". Journal of Translational Medicine. 11: 137. PMID 23731854 DOI: 10.1186/1479-5876-11-137  0.084
2008 Hondowicz BD, Fields ML, Nish SA, Larkin J, Caton AJ, Erikson J. Autoantibody production in lpr/lpr gld/gld mice reflects accumulation of CD4+ effector cells that are resistant to regulatory T cell activity. Journal of Autoimmunity. 31: 98-109. PMID 18539433 DOI: 10.1016/J.Jaut.2008.04.022  0.083
2015 Weber JS, D'Angelo SP, Minor D, Hodi FS, Gutzmer R, Neyns B, Hoeller C, Khushalani NI, Miller WH, Lao CD, Linette GP, Thomas L, Lorigan P, Grossmann KF, Hassel JC, ... ... Larkin J, et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial. The Lancet. Oncology. 16: 375-84. PMID 25795410 DOI: 10.1016/S1470-2045(15)70076-8  0.083
2006 Collins CG, Tangney M, Larkin JO, Casey G, Whelan MC, Cashman J, Murphy J, Soden D, Vejda S, McKenna S, Kiely B, Collins JK, Barrett J, Aarons S, O'Sullivan GC. Local gene therapy of solid tumors with GM-CSF and B7-1 eradicates both treated and distal tumors. Cancer Gene Therapy. 13: 1061-71. PMID 16874363 DOI: 10.1038/sj.cgt.7700976  0.082
2013 Khattak M, Fisher R, Turajlic S, Larkin J. Targeted therapy and immunotherapy in advanced melanoma: an evolving paradigm. Therapeutic Advances in Medical Oncology. 5: 105-18. PMID 23450149 DOI: 10.1177/1758834012466280  0.082
2012 Karapanagiotou EM, Roulstone V, Twigger K, Ball M, Tanay M, Nutting C, Newbold K, Gore ME, Larkin J, Syrigos KN, Coffey M, Thompson B, Mettinger K, Vile RG, Pandha HS, et al. Phase I/II trial of carboplatin and paclitaxel chemotherapy in combination with intravenous oncolytic reovirus in patients with advanced malignancies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 2080-9. PMID 22316603 DOI: 10.1158/1078-0432.Ccr-11-2181  0.082
2011 Sanz-Moreno V, Gaggioli C, Yeo M, Albrengues J, Wallberg F, Viros A, Hooper S, Mitter R, Féral CC, Cook M, Larkin J, Marais R, Meneguzzi G, Sahai E, Marshall CJ. ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma. Cancer Cell. 20: 229-45. PMID 21840487 DOI: 10.1016/j.ccr.2011.06.018  0.081
2014 Gupta A, Love S, Schuh A, Shanyinde M, Larkin JM, Plummer R, Nathan PD, Danson S, Ottensmeier CH, Lorigan P, Collins L, Wise A, Asher R, Lisle R, Middleton MR. DOC-MEK: a double-blind randomized phase II trial of docetaxel with or without selumetinib in wild-type BRAF advanced melanoma. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 25: 968-74. PMID 24567366 DOI: 10.1093/annonc/mdu054  0.081
2011 Perazza D, Laporte F, Balagué C, Chevalier F, Remo S, Bourge M, Larkin J, Herzog M, Vachon G. GeBP/GPL transcription factors regulate a subset of CPR5-dependent processes. Plant Physiology. 157: 1232-42. PMID 21875893 DOI: 10.1104/Pp.111.179804  0.081
2015 Chilcote J, Barman T, Fitzgerald MP, Graham JR, Larkin JE, Macintosh B, Bauman B, Burrows AS, Cardwell A, De Rosa RJ, Dillon D, Doyon R, Dunn J, Erikson D, Gavel D, et al. The first H-band spectrum of the giant planet β Pictoris b Astrophysical Journal Letters. 798. DOI: 10.1088/2041-8205/798/1/L3  0.08
2015 Long GV, Stroyakovskiy D, Gogas H, Levchenko E, de Braud F, Larkin J, Garbe C, Jouary T, Hauschild A, Grob JJ, Chiarion-Sileni V, Lebbe C, Mandalà M, Millward M, Arance A, et al. Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial. Lancet (London, England). 386: 444-51. PMID 26037941 DOI: 10.1016/S0140-6736(15)60898-4  0.08
2014 Macintosh B, Graham JR, Ingraham P, Konopacky Q, Marois C, Perrin M, Poyneer L, Bauman B, Barman T, Burrows AS, Cardwell A, Chilcote J, De Rosa RJ, Dillon D, Doyon R, ... Larkin J, et al. First light of the Gemini Planet imager. Proceedings of the National Academy of Sciences of the United States of America. 111: 12661-6. PMID 24821792 DOI: 10.1073/Pnas.1304215111  0.08
2012 Larkin JD, Cook PR, Papantonis A. Dynamic reconfiguration of long human genes during one transcription cycle. Molecular and Cellular Biology. 32: 2738-47. PMID 22586273 DOI: 10.1128/Mcb.00179-12  0.08
2014 Zimmer L, Barlesi F, Martinez-Garcia M, Dieras V, Schellens JH, Spano JP, Middleton MR, Calvo E, Paz-Ares L, Larkin J, Pacey S, Venturi M, Kraeber-Bodéré F, Tessier JJ, Eberhardt WE, et al. Phase I expansion and pharmacodynamic study of the oral MEK inhibitor RO4987655 (CH4987655) in selected patients with advanced cancer with RAS-RAF mutations. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 4251-61. PMID 24947927 DOI: 10.1158/1078-0432.Ccr-14-0341  0.079
2015 Stacy SL, Brink LL, Larkin JC, Sadovsky Y, Goldstein BD, Pitt BR, Talbott EO. Perinatal outcomes and unconventional natural gas operations in southwest pennsylvania. Plos One. 10: e0126425. PMID 26039051 DOI: 10.1371/Journal.Pone.0126425  0.079
2015 Motzer RJ, Escudier B, McDermott DF, George S, Hammers HJ, Srinivas S, Tykodi SS, Sosman JA, Procopio G, Plimack ER, Castellano D, Choueiri TK, Gurney H, Donskov F, Bono P, ... ... Larkin J, et al. Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma. The New England Journal of Medicine. PMID 26406148 DOI: 10.1056/NEJMoa1510665  0.078
2011 Fisher R, Larkin J, Swanton C. Delivering preventive, predictive and personalised cancer medicine for renal cell carcinoma: the challenge of tumour heterogeneity. The Epma Journal. 3: 1. PMID 22738081 DOI: 10.1007/S13167-011-0137-3  0.078
2009 Larkin JM, Kipps EL, Powell CJ, Swanton C. Systemic therapy for advanced renal cell carcinoma. Therapeutic Advances in Medical Oncology. 1: 15-27. PMID 21789110 DOI: 10.1177/1758834009338430  0.078
2010 Van Leene J, Hollunder J, Eeckhout D, Persiau G, Van De Slijke E, Stals H, Van Isterdael G, Verkest A, Neirynck S, Buffel Y, De Bodt S, Maere S, Laukens K, Pharazyn A, Ferreira PC, ... Larkin JC, et al. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Molecular Systems Biology. 6: 397. PMID 20706207 DOI: 10.1038/msb.2010.53  0.078
2011 Khan OA, Gore M, Lorigan P, Stone J, Greystoke A, Burke W, Carmichael J, Watson AJ, McGown G, Thorncroft M, Margison GP, Califano R, Larkin J, Wellman S, Middleton MR. A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours. British Journal of Cancer. 104: 750-5. PMID 21326243 DOI: 10.1038/bjc.2011.8  0.078
2013 Furney SJ, Turajlic S, Stamp G, Nohadani M, Carlisle A, Thomas JM, Hayes A, Strauss D, Gore M, van den Oord J, Larkin J, Marais R. Genome sequencing of mucosal melanomas reveals that they are driven by distinct mechanisms from cutaneous melanoma. The Journal of Pathology. 230: 261-9. PMID 23620124 DOI: 10.1002/path.4204  0.078
2015 Dickens AM, Larkin JR, Davis BG, Griffin JL, Claridge TD, Sibson NR, Anthony DC. NMR-Based Metabolomics Separates the Distinct Stages of Disease in a Chronic Relapsing Model of Multiple Sclerosis. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 10: 435-44. PMID 26155956 DOI: 10.1007/S11481-015-9622-0  0.077
2014 Kelderman S, Heemskerk B, van Tinteren H, van den Brom RR, Hospers GA, van den Eertwegh AJ, Kapiteijn EW, de Groot JW, Soetekouw P, Jansen RL, Fiets E, Furness AJ, Renn A, Krzystanek M, Szallasi Z, ... ... Larkin JM, et al. Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma. Cancer Immunology, Immunotherapy : Cii. 63: 449-58. PMID 24609989 DOI: 10.1007/S00262-014-1528-9  0.077
2013 Fisher R, Gore M, Larkin J. Current and future systemic treatments for renal cell carcinoma. Seminars in Cancer Biology. 23: 38-45. PMID 22705280 DOI: 10.1016/j.semcancer.2012.06.004  0.077
2011 Kasili R, Huang CC, Walker JD, Simmons LA, Zhou J, Faulk C, Hülskamp M, Larkin JC. BRANCHLESS TRICHOMES links cell shape and cell cycle control in Arabidopsis trichomes. Development (Cambridge, England). 138: 2379-88. PMID 21558384 DOI: 10.1242/Dev.058982  0.076
2015 Marshall KM, Nowaczyk L, Morrissey TR, Loeza V, Halik LA, Skinner GE, Reddy NR, Fleischman GJ, Larkin JW. Effect of sporulation temperature on the resistance of Clostridium botulinum type A spores to thermal and high pressure processing. Journal of Food Protection. 78: 146-50. PMID 25581189 DOI: 10.4315/0362-028X.JFP-14-186  0.076
2015 Soultati A, Stares M, Swanton C, Larkin J, Turajlic S. How should clinicians address intratumour heterogeneity in clear cell renal cell carcinoma? Current Opinion in Urology. 25: 358-66. PMID 26125509 DOI: 10.1097/Mou.0000000000000204  0.076
2010 Papantonis A, Larkin JD, Wada Y, Ohta Y, Ihara S, Kodama T, Cook PR. Active RNA polymerases: mobile or immobile molecular machines? Plos Biology. 8: e1000419. PMID 20644712 DOI: 10.1371/Journal.Pbio.1000419  0.076
2013 Reddy NR, Marshall KM, Morrissey TR, Loeza V, Patazca E, Skinner GE, Krishnamurthy K, Larkin JW. Combined high pressure and thermal processing on inactivation of type A and proteolytic type B spores of Clostridium botulinum. Journal of Food Protection. 76: 1384-92. PMID 23905794 DOI: 10.4315/0362-028X.JFP-12-538  0.076
2015 Kalas PG, Rajan A, Wang JJ, Millar-Blanchaer MA, Duchene G, Chen C, Fitzgerald MP, Dong R, Graham JR, Patience J, Macintosh B, Murray-Clay R, Matthews B, Rameau J, Marois C, ... Larkin JE, et al. Direct imaging of an asymmetric debris disk in the HD 106906 planetary system Astrophysical Journal. 814. DOI: 10.1088/0004-637X/814/1/32  0.076
2013 Qasba P, Larkin J. NHLBI support of systems biology. Frontiers in Physiology. 4: 299. PMID 24298257 DOI: 10.3389/fphys.2013.00299  0.075
2015 Ascierto PA, McArthur GA, Dréno B, Larkin J, Liszkay G, Maio M, Mandala M, Demidov L, Stroyakovskiy D, Thomas L, de la Cruz-Merino L, Atkinson V, Dutriaux C, Garbe C, Chang I, et al. coBRIM: a phase 3, double-blind, placebo-controlled study of vemurafenib versus vemurafenib + cobimetinib in previously untreated BRAF (V600) mutation-positive patients with unresectable locally advanced or metastatic melanoma (NCT01689519). Journal of Translational Medicine. 13: 2061. PMID 25779180 DOI: 10.1186/1479-5876-13-S1-O4  0.075
2014 Turajlic S, Furney SJ, Stamp G, Rana S, Ricken G, Oduko Y, Saturno G, Springer C, Hayes A, Gore M, Larkin J, Marais R. Whole-genome sequencing reveals complex mechanisms of intrinsic resistance to BRAF inhibition. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 25: 959-67. PMID 24504448 DOI: 10.1093/annonc/mdu049  0.075
2014 Gerlinger M, Horswell S, Larkin J, Rowan AJ, Salm MP, Varela I, Fisher R, McGranahan N, Matthews N, Santos CR, Martinez P, Phillimore B, Begum S, Rabinowitz A, Spencer-Dene B, et al. Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing. Nature Genetics. 46: 225-33. PMID 24487277 DOI: 10.1038/Ng.2891  0.075
2012 Turajlic S, Furney SJ, Lambros MB, Mitsopoulos C, Kozarewa I, Geyer FC, Mackay A, Hakas J, Zvelebil M, Lord CJ, Ashworth A, Thomas M, Stamp G, Larkin J, Reis-Filho JS, et al. Whole genome sequencing of matched primary and metastatic acral melanomas. Genome Research. 22: 196-207. PMID 22183965 DOI: 10.1101/gr.125591.111  0.075
2011 Jager LD, Dabelic R, Waiboci LW, Lau K, Haider MS, Ahmed CM, Larkin J, David S, Johnson HM. The kinase inhibitory region of SOCS-1 is sufficient to inhibit T-helper 17 and other immune functions in experimental allergic encephalomyelitis. Journal of Neuroimmunology. 232: 108-18. PMID 21131060 DOI: 10.1016/J.Jneuroim.2010.10.018  0.074
2011 Fisher R, Pickering L, Larkin J. New targeted therapies for renal cell carcinoma. Expert Opinion On Investigational Drugs. 20: 933-45. PMID 21506895 DOI: 10.1517/13543784.2011.577065  0.074
2006 Larkin J, Renukaradhya GJ, Sriram V, Du W, Gervay-Hague J, Brutkiewicz RR. CD44 differentially activates mouse NK T cells and conventional T cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 268-79. PMID 16785522 DOI: 10.4049/Jimmunol.177.1.268  0.074
2012 Fisher R, Larkin J. Vemurafenib: a new treatment for BRAF-V600 mutated advanced melanoma. Cancer Management and Research. 4: 243-52. PMID 22904646 DOI: 10.2147/CMAR.S25284  0.074
2010 Mukherji D, Larkin J, Pickering L. Sunitinib for metastatic renal cell carcinoma. Future Oncology (London, England). 6: 1377-85. PMID 20919823 DOI: 10.2217/fon.10.94  0.073
2015 Gray E, Larkin JR, Claridge TD, Talbot K, Sibson NR, Turner MR. The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 26121274 DOI: 10.3109/21678421.2015.1053490  0.073
2013 Girotti MR, Pedersen M, Sanchez-Laorden B, Viros A, Turajlic S, Niculescu-Duvaz D, Zambon A, Sinclair J, Hayes A, Gore M, Lorigan P, Springer C, Larkin J, Jorgensen C, Marais R. Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma. Cancer Discovery. 3: 158-67. PMID 23242808 DOI: 10.1158/2159-8290.CD-12-0386  0.072
2010 Rennalls LP, Seidl T, Larkin JM, Wellbrock C, Gore ME, Eisen T, Bruno L. The melanocortin receptor agonist NDP-MSH impairs the allostimulatory function of dendritic cells. Immunology. 129: 610-9. PMID 20074207 DOI: 10.1111/j.1365-2567.2009.03210.x  0.072
2014 Thian Y, Gutzeit A, Koh DM, Fisher R, Lote H, Larkin J, Sohaib A. Revised Choi imaging criteria correlate with clinical outcomes in patients with metastatic renal cell carcinoma treated with sunitinib. Radiology. 273: 452-61. PMID 24869795 DOI: 10.1148/radiol.14132702  0.072
1998 Ganim RB, Peckol EL, Larkin J, Ruchhoeft ML, Cameron JS. ATP-sensitive K+ channels in cardiac muscle from cold-acclimated goldfish: characterization and altered response to ATP. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 119: 395-401. PMID 11253812 DOI: 10.1016/S1095-6433(97)00443-1  0.072
2010 Swanton C, Larkin JM, Gerlinger M, Eklund AC, Howell M, Stamp G, Downward J, Gore M, Futreal PA, Escudier B, Andre F, Albiges L, Beuselinck B, Oudard S, Hoffmann J, et al. Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets. Genome Medicine. 2: 53. PMID 20701793 DOI: 10.1186/Gm174  0.072
2015 Motzer RJ, Hutson TE, Glen H, Michaelson MD, Molina A, Eisen T, Jassem J, Zolnierek J, Maroto JP, Mellado B, Melichar B, Tomasek J, Kremer A, Kim HJ, Wood K, ... ... Larkin J, et al. Lenvatinib, everolimus, and the combination in patients with metastatic renal cell carcinoma: a randomised, phase 2, open-label, multicentre trial. The Lancet. Oncology. 16: 1473-82. PMID 26482279 DOI: 10.1016/S1470-2045(15)00290-9  0.072
2006 Soden DM, Larkin JO, Collins CG, Tangney M, Aarons S, Piggott J, Morrissey A, Dunne C, O'Sullivan GC. Successful application of targeted electrochemotherapy using novel flexible electrodes and low dose bleomycin to solid tumours. Cancer Letters. 232: 300-10. PMID 15964138 DOI: 10.1016/j.canlet.2005.03.057  0.072
2013 Larkin J, Ahmed CM, Wilson TD, Johnson HM. Regulation of interferon gamma signaling by suppressors of cytokine signaling and regulatory T cells. Frontiers in Immunology. 4: 469. PMID 24391643 DOI: 10.3389/Fimmu.2013.00469  0.071
2012 Flaherty KT, Robert C, Hersey P, Nathan P, Garbe C, Milhem M, Demidov LV, Hassel JC, Rutkowski P, Mohr P, Dummer R, Trefzer U, Larkin JM, Utikal J, Dreno B, et al. Improved survival with MEK inhibition in BRAF-mutated melanoma. The New England Journal of Medicine. 367: 107-14. PMID 22663011 DOI: 10.1056/NEJMoa1203421  0.071
2014 Khattak M, Larkin J. Sequential therapy with targeted agents in metastatic renal cell carcinoma: beyond second-line and overcoming drug resistance. World Journal of Urology. 32: 19-29. PMID 23297098 DOI: 10.1007/s00345-012-1013-z  0.071
2011 Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, Dummer R, Garbe C, Testori A, Maio M, Hogg D, Lorigan P, Lebbe C, Jouary T, Schadendorf D, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. The New England Journal of Medicine. 364: 2507-16. PMID 21639808 DOI: 10.1056/Nejmoa1103782  0.071
2015 Wilkins A, Furness A, W Corbett R, Bloomfield A, Porta N, Morris S, Ali Z, Larkin J, Harrington K. The melanoma-specific graded prognostic assessment does not adequately discriminate prognosis in a modern population with brain metastases from malignant melanoma. British Journal of Cancer. 113: 1275-81. PMID 26484413 DOI: 10.1038/Bjc.2015.357  0.07
2006 Larkin J, Tangney M, Collins C, Casey G, O'Brien MG, Soden D, O'Sullivan GC. Oral immune tolerance mediated by suppressor T cells may be responsible for the poorer prognosis of foregut cancers. Medical Hypotheses. 66: 541-4. PMID 16288967 DOI: 10.1016/j.mehy.2005.09.021  0.07
2014 Benson C, Vitfell-Rasmussen J, Maruzzo M, Fisher C, Tunariu N, Mitchell S, Al-Muderis O, Thway K, Larkin J, Judson I. A retrospective study of patients with malignant PEComa receiving treatment with sirolimus or temsirolimus: the Royal Marsden Hospital experience. Anticancer Research. 34: 3663-8. PMID 24982384  0.07
2008 Jakoby MJ, Falkenhan D, Mader MT, Brininstool G, Wischnitzki E, Platz N, Hudson A, Hülskamp M, Larkin J, Schnittger A. Transcriptional profiling of mature Arabidopsis trichomes reveals that NOECK encodes the MIXTA-like transcriptional regulator MYB106. Plant Physiology. 148: 1583-602. PMID 18805951 DOI: 10.1104/pp.108.126979  0.07
2015 Schadendorf D, Amonkar MM, Stroyakovskiy D, Levchenko E, Gogas H, de Braud F, Grob JJ, Bondarenko I, Garbe C, Lebbe C, Larkin J, Chiarion-Sileni V, Millward M, Arance A, Mandalà M, et al. Health-related quality of life impact in a randomised phase III study of the combination of dabrafenib and trametinib versus dabrafenib monotherapy in patients with BRAF V600 metastatic melanoma. European Journal of Cancer (Oxford, England : 1990). 51: 833-40. PMID 25794603 DOI: 10.1016/j.ejca.2015.03.004  0.07
2014 Larkin J, Ascierto PA, Dréno B, Atkinson V, Liszkay G, Maio M, Mandalà M, Demidov L, Stroyakovskiy D, Thomas L, de la Cruz-Merino L, Dutriaux C, Garbe C, Sovak MA, Chang I, et al. Combined vemurafenib and cobimetinib in BRAF-mutated melanoma. The New England Journal of Medicine. 371: 1867-76. PMID 25265494 DOI: 10.1056/NEJMoa1408868  0.07
2015 Martin-Liberal J, Larkin J. Vemurafenib for the treatment of BRAF mutant metastatic melanoma. Future Oncology (London, England). 11: 579-89. PMID 25686114 DOI: 10.2217/fon.14.252  0.069
2015 Coupe N, Corrie P, Hategan M, Larkin J, Gore M, Gupta A, Wise A, Suter S, Ciria C, Love S, Collins L, Middleton MR. PACMEL: a phase 1 dose escalation trial of trametinib (GSK1120212) in combination with paclitaxel. European Journal of Cancer (Oxford, England : 1990). 51: 359-66. PMID 25542057 DOI: 10.1016/j.ejca.2014.11.018  0.069
2015 Ugurel S, Röhmel J, Ascierto PA, Flaherty KT, Grob JJ, Hauschild A, Larkin J, Long GV, Lorigan P, McArthur GA, Ribas A, Robert C, Schadendorf D, Garbe C. Survival of patients with advanced metastatic melanoma: The impact of novel therapies. European Journal of Cancer (Oxford, England : 1990). 53: 125-134. PMID 26707829 DOI: 10.1016/j.ejca.2015.09.013  0.069
2015 Dummer R, Schadendorf D, Ascierto PA, Larkin J, Lebbé C, Hauschild A. Integrating first-line treatment options into clinical practice: what's new in advanced melanoma? Melanoma Research. 25: 461-9. PMID 26426764 DOI: 10.1097/CMR.0000000000000200  0.069
2008 Rankin AL, Reed AJ, Oh S, Cozzo Picca C, Guay HM, Larkin J, Panarey L, Aitken MK, Koeberlein B, Lipsky PE, Tomaszewski JE, Naji A, Caton AJ. CD4+ T cells recognizing a single self-peptide expressed by APCs induce spontaneous autoimmune arthritis. Journal of Immunology (Baltimore, Md. : 1950). 180: 833-41. PMID 18178822 DOI: 10.4049/Jimmunol.180.2.833  0.068
2015 Ahmed CM, Larkin J, Johnson HM. SOCS1 Mimetics and Antagonists: A Complementary Approach to Positive and Negative Regulation of Immune Function. Frontiers in Immunology. 6: 183. PMID 25954276 DOI: 10.3389/Fimmu.2015.00183  0.068
2015 Larkin J, Hatswell AJ, Nathan P, Lebmeier M, Lee D. The Predicted Impact of Ipilimumab Usage on Survival in Previously Treated Advanced or Metastatic Melanoma in the UK. Plos One. 10: e0145524. PMID 26700304 DOI: 10.1371/Journal.Pone.0145524  0.067
2015 Moriceau G, Hugo W, Hong A, Shi H, Kong X, Yu CC, Koya RC, Samatar AA, Khanlou N, Braun J, Ruchalski K, Seifert H, Larkin J, Dahlman KB, Johnson DB, et al. Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction. Cancer Cell. 27: 240-56. PMID 25600339 DOI: 10.1016/J.Ccell.2014.11.018  0.067
2011 Collins EL, Jager LD, Dabelic R, Benitez P, Holdstein K, Lau K, Haider MI, Johnson HM, Larkin J. Inhibition of SOCS1-/- lethal autoinflammatory disease correlated to enhanced peripheral Foxp3+ regulatory T cell homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 187: 2666-76. PMID 21788442 DOI: 10.4049/Jimmunol.1003819  0.067
2005 Larkin JM, Gore ME. The MRC randomised-controlled trial of interferon-alpha, interleukin-2 and 5-fluorouracil vs interferon-alpha alone in patients with advanced renal cell carcinoma (RE04): rationale and progress. Clinical Oncology (Royal College of Radiologists (Great Britain)). 17: 319-21. PMID 16097560 DOI: 10.1016/J.CLON.2005.03.007  0.067
2006 Evans MD, Larouche RX, Olivares M, Léger P, Larkin J, Freeman CR, Podgorsak EB. Total body irradiation with a reconditioned cobalt teletherapy unit. Journal of Applied Clinical Medical Physics / American College of Medical Physics. 7: 42-51. PMID 16518316 DOI: 10.1120/Jacmp.V7I1.2175  0.067
2012 Jackson EE, Erten ES, Maddi N, Graham TE, Larkin JW, Blodgett RJ, Schlesser JE, Reddy RM. Detection and enumeration of four foodborne pathogens in raw commingled silo milk in the United States. Journal of Food Protection. 75: 1382-93. PMID 22856561 DOI: 10.4315/0362-028X.JFP-11-548  0.066
2015 Jamal-Hanjani M, Quezada SA, Larkin J, Swanton C. Translational implications of tumor heterogeneity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1258-66. PMID 25770293 DOI: 10.1158/1078-0432.Ccr-14-1429  0.066
2015 Thomas CL, Mortimer PS, Larkin JM, Basu TN, Gore ME, Fearfield L. A mitogen-activated protein kinase kinase inhibitor induced compound skin toxicity with oedema in metastatic malignant melanoma. Clinical and Experimental Dermatology. PMID 26411345 DOI: 10.1111/ced.12722  0.066
2012 Grünwald V, Karakiewicz PI, Bavbek SE, Miller K, Machiels JP, Lee SH, Larkin J, Bono P, Rha SY, Castellano D, Blank CU, Knox JJ, Hawkins R, Anak O, Rosamilia M, et al. An international expanded-access programme of everolimus: addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy. European Journal of Cancer (Oxford, England : 1990). 48: 324-32. PMID 21803569 DOI: 10.1016/J.Ejca.2011.06.054  0.066
2010 Larkin JM, Ferguson TR, Pickering LM, Edmonds K, James MG, Thomas K, Banerji U, Berns B, de Boer C, Gore ME. A phase I/II trial of sorafenib and infliximab in advanced renal cell carcinoma. British Journal of Cancer. 103: 1149-53. PMID 20842130 DOI: 10.1038/sj.bjc.6605889  0.065
2013 Gerlinger M, Quezada SA, Peggs KS, Furness AJ, Fisher R, Marafioti T, Shende VH, McGranahan N, Rowan AJ, Hazell S, Hamm D, Robins HS, Pickering L, Gore M, Nicol DL, ... Larkin J, et al. Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas. The Journal of Pathology. 231: 424-32. PMID 24122851 DOI: 10.1002/Path.4284  0.065
2014 Fisher R, Horswell S, Rowan A, Salm MP, de Bruin EC, Gulati S, McGranahan N, Stares M, Gerlinger M, Varela I, Crockford A, Favero F, Quidville V, André F, Navas C, ... ... Larkin J, et al. Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution. Genome Biology. 15: 433. PMID 25159823 DOI: 10.1186/S13059-014-0433-Z  0.065
2013 Larkin JD, Papantonis A, Cook PR, Marenduzzo D. Space exploration by the promoter of a long human gene during one transcription cycle. Nucleic Acids Research. 41: 2216-27. PMID 23303786 DOI: 10.1093/Nar/Gks1441  0.065
2005 Larkin JM, Porter CD. Mice are unsuitable for modelling ABO discordance despite strain-specific A cross-reactive natural IgM. British Journal of Haematology. 130: 310-7. PMID 16029461 DOI: 10.1111/j.1365-2141.2005.05609.x  0.065
2015 Martin-Liberal J, Kordbacheh T, Larkin J. Safety of pembrolizumab for the treatment of melanoma. Expert Opinion On Drug Safety. 14: 957-64. PMID 25927979 DOI: 10.1517/14740338.2015.1021774  0.064
2012 Woods R, Larkin JO, Muldoon C, Kennedy MJ, Mehigan B, McCormick P. Metastatic paediatric colorectal carcinoma. Irish Medical Journal. 105: 88-9. PMID 22558819  0.064
2008 Hensley ML, Larkin J, Fury M, Gerst S, Tai DF, Sabbatini P, Konner J, Orlando M, Goss TL, Aghajanian CA. A phase I trial of pemetrexed plus gemcitabine given biweekly with B-vitamin support in solid tumor malignancies or advanced epithelial ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 6310-6. PMID 18829514 DOI: 10.1158/1078-0432.CCR-08-0338  0.063
2014 Wright SA, Larkin JE, Moore AM, Do T, Simard L, Adamkovics M, Armus L, Barth AJ, Barton E, Boyce H, Cooke J, Cote P, Davidge T, Ellerbroek B, Ghez AM, et al. The infrared imaging spectrograph (IRIS) for TMT: Overview of innovative science programs Proceedings of Spie - the International Society For Optical Engineering. 9147. DOI: 10.1117/12.2055599  0.063
2013 O'Sullivan KE, Moriarty AR, Larkin JO, Reynolds JV. Curative surgical management of isolated adrenal recurrence of oesophageal adenocarcinoma. Bmj Case Reports. 2013. PMID 23632191 DOI: 10.1136/bcr-2013-009657  0.063
2013 Keller SE, Shazer AG, Fleischman GJ, Chirtel S, Anderson N, Larkin J. "Thermal inactivation of campylobacter jejuni in broth," a comment on: J. Food Prot. 75(6):1029-1035 (2012). Journal of Food Protection. 76: 928. PMID 23726185 DOI: 10.4315/0362-028X.76.6.928  0.062
2011 Larkin JM, Fisher RA, Pickering LM, Sohaib SA, Ghosn M, Christmas T, Cordiner RL, Gore ME. Chromophobe renal cell carcinoma with prolonged response to sequential sunitinib and everolimus. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e241-2. PMID 21245426 DOI: 10.1200/JCO.2010.33.4375  0.062
2006 Larkin JM, Norsworthy PJ, A'Hern RP, Eisen TG, Gore ME, Porter CD. Anti-alphaGal-dependent complement-mediated cytotoxicity in metastatic melanoma. Melanoma Research. 16: 157-63. PMID 16567971 DOI: 10.1097/01.cmr.0000200490.62723.b0  0.062
2013 Larkin JD, Papantonis A, Cook PR. Promoter type influences transcriptional topography by targeting genes to distinct nucleoplasmic sites. Journal of Cell Science. 126: 2052-9. PMID 23444365 DOI: 10.1242/Jcs.123653  0.062
2005 Larkin JE, Frank BC, Gavras H, Sultana R, Quackenbush J. Independence and reproducibility across microarray platforms. Nature Methods. 2: 337-44. PMID 15846360 DOI: 10.1038/Nmeth757  0.062
2013 Sinha R, Edmonds K, Newton-Bishop J, Gore M, Larkin J, Fearfield L. Erythema nodosum-like panniculitis in patients with melanoma treated with vemurafenib. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: e320-1. PMID 23715570 DOI: 10.1200/JCO.2012.45.8307  0.062
2009 Tajchner L, Larkin JO, Bourke MG, Waldron R, Barry K, Eustace PW. Management of the acute scrotum in a district general hospital: 10-year experience. Thescientificworldjournal. 9: 281-6. PMID 19412556 DOI: 10.1100/tsw.2009.37  0.062
2014 Larkin J, Del Vecchio M, Ascierto PA, Krajsova I, Schachter J, Neyns B, Espinosa E, Garbe C, Sileni VC, Gogas H, Miller WH, Mandalà M, Hospers GA, Arance A, Queirolo P, et al. Vemurafenib in patients with BRAF(V600) mutated metastatic melanoma: an open-label, multicentre, safety study. The Lancet. Oncology. 15: 436-44. PMID 24582505 DOI: 10.1016/S1470-2045(14)70051-8  0.062
2003 Sproule JA, Kumar S, Larkin J, O'Rourke SK. Odontoid-lateral mass asymmetry in minimally symptomatic patients: a normal variant European Journal of Orthopaedic Surgery & Traumatology. 13: 63-66. DOI: 10.1007/s00590-003-0071-8  0.061
2005 Villarino AV, Larkin J, Saris CJ, Caton AJ, Lucas S, Wong T, de Sauvage FJ, Hunter CA. Positive and negative regulation of the IL-27 receptor during lymphoid cell activation. Journal of Immunology (Baltimore, Md. : 1950). 174: 7684-91. PMID 15944269 DOI: 10.4049/Jimmunol.174.12.7684  0.061
2015 Bridgeman VL, Wan E, Foo S, Nathan MR, Welti JC, Frentzas S, Vermeulen PB, Preece N, Springer CJ, Powles T, Nathan PD, Larkin J, Gore M, Vasudev N, Reynolds AR. Preclinical evidence that trametinib enhances the response to anti-angiogenic tyrosine kinase inhibitors in renal cell carcinoma. Molecular Cancer Therapeutics. PMID 26487278 DOI: 10.1158/1535-7163.MCT-15-0170  0.061
2006 Larkin JD, Bhat KL, Markham GD, Brooks BR, Schaefer HF, Bock CW. Structure of the boronic acid dimer and the relative stabilities of its conformers. The Journal of Physical Chemistry. A. 110: 10633-42. PMID 16956246 DOI: 10.1021/jp062407h  0.061
2015 Larkin JD, Cook PR. Super-resolution measurement of distance between transcription sites using RNA FISH with intronic probes. Methods (San Diego, Calif.). PMID 26564237 DOI: 10.1016/J.Ymeth.2015.11.009  0.061
2015 Richman J, Martin-Liberal J, Diem S, Larkin J. BRAF and MEK inhibition for the treatment of advanced BRAF mutant melanoma. Expert Opinion On Pharmacotherapy. 16: 1285-97. PMID 26001180 DOI: 10.1517/14656566.2015.1044971  0.061
2015 Sinha R, Larkin J, Gore M, Fearfield L. Cutaneous toxicities associated with vemurafenib therapy in 107 patients with BRAF V600E mutation-positive metastatic melanoma, including recognition and management of rare presentations. The British Journal of Dermatology. 173: 1024-31. PMID 26109403 DOI: 10.1111/bjd.13958  0.061
2011 Woodcock HL, Miller BT, Hodoscek M, Okur A, Larkin JD, Ponder JW, Brooks BR. MSCALE: A General Utility for Multiscale Modeling. Journal of Chemical Theory and Computation. 7: 1208-1219. PMID 21691425 DOI: 10.1021/Ct100738H  0.061
2008 Brininstool G, Kasili R, Simmons LA, Kirik V, Hülskamp M, Larkin JC. Constitutive Expressor Of Pathogenesis-related Genes5 affects cell wall biogenesis and trichome development. Bmc Plant Biology. 8: 58. PMID 18485217 DOI: 10.1186/1471-2229-8-58  0.061
2010 Larkin J, Fisher R, Pickering L, Thway K, Livni N, Fisher C, Gore M. Metastatic mucinous tubular and spindle cell carcinoma of the kidney responding to sunitinib. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: e539-40. PMID 20679595 DOI: 10.1200/JCO.2010.30.1457  0.06
2015 Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, Schadendorf D, Dummer R, Smylie M, Rutkowski P, Ferrucci PF, Hill A, Wagstaff J, Carlino MS, Haanen JB, et al. Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma. The New England Journal of Medicine. 373: 23-34. PMID 26027431 DOI: 10.1056/Nejmoa1504030  0.06
2007 Ye Z, Koutchma T, Parisi B, Larkin J, Forney LJ. Ultraviolet inactivation kinetics of Escherichia coli and Yersinia pseudotuberculosis in annular reactors. Journal of Food Science. 72: E271-8. PMID 17995726 DOI: 10.1111/j.1750-3841.2007.00397.x  0.06
2014 Hartung M, Hayward T, Saddlemyer L, Poyneer L, Cardwell A, Cavedoni C, Cho M, Chilcote JK, Collins P, Dillon D, Galvez R, Gausachs G, Goodsell S, Guesalaga A, Hibon P, Larkin J, et al. On-sky vibration environment for the Gemini Planet Imager and mitigation effort Proceedings of Spie - the International Society For Optical Engineering. 9148. DOI: 10.1117/12.2057200  0.06
2006 Owens ZT, Larkin JD, Schaefer HF. Hydrogen bridging in the compounds X2H (X=Al,Si,P,S). The Journal of Chemical Physics. 125: 164322. PMID 17092088 DOI: 10.1063/1.2363375  0.06
2011 Larkin JO, Cooke F, Ravi N, Reynolds JV. Internal hernia following total gastrectomy with Roux-en-Y reconstruction. Annals of the Royal College of Surgeons of England. 93: e71-3. PMID 21929889 DOI: 10.1308/147870811X590333  0.059
2015 Macintosh B, Graham JR, Barman T, De Rosa RJ, Konopacky Q, Marley MS, Marois C, Nielsen EL, Pueyo L, Rajan A, Rameau J, Saumon D, Wang JJ, Ammons M, Arriaga P, ... Larkin JE, et al. Discovery and spectroscopy of the young Jovian planet 51 Eri b with the Gemini Planet Imager. Science (New York, N.Y.). PMID 26272904 DOI: 10.1126/Science.Aac5891  0.059
2015 Turajlic S, Larkin J, Swanton C. SnapShot: Renal Cell Carcinoma. Cell. 163: 1556-1556.e1. PMID 26638079 DOI: 10.1016/J.Cell.2015.11.026  0.059
2015 Porta C, Tortora G, Larkin JM, Hutson TE. Management of poor-risk metastatic renal cell carcinoma: current approaches, the role of temsirolimus and future directions. Future Oncology (London, England). PMID 26606910 DOI: 10.2217/fon.15.313  0.059
2015 Rothermundt C, Bailey A, Cerbone L, Eisen T, Escudier B, Gillessen S, Grünwald V, Larkin J, McDermott D, Oldenburg J, Porta C, Rini B, Schmidinger M, Sternberg C, Putora PM. Algorithms in the First-Line Treatment of Metastatic Clear Cell Renal Cell Carcinoma--Analysis Using Diagnostic Nodes. The Oncologist. 20: 1028-35. PMID 26240132 DOI: 10.1634/theoncologist.2015-0145  0.058
2015 Robert C, Schachter J, Long GV, Arance A, Grob JJ, Mortier L, Daud A, Carlino MS, McNeil C, Lotem M, Larkin J, Lorigan P, Neyns B, Blank CU, Hamid O, et al. Pembrolizumab versus Ipilimumab in Advanced Melanoma. The New England Journal of Medicine. 372: 2521-32. PMID 25891173 DOI: 10.1056/NEJMoa1503093  0.058
2012 Fisher R, Pender A, Thillai K, Chowdhury S, Pickering L, Khabra K, Gore M, Larkin J. Observation as a treatment strategy for advanced renal cell carcinoma-a call for prospective validation. Frontiers in Oncology. 2: 155. PMID 23120744 DOI: 10.3389/fonc.2012.00155  0.058
2013 Larkin J, Paine A, Tumur I, Cappelleri JC, Healey PJ, Foley G, Mitchell S, Kroes M, Chen C. Second-line treatments for the management of advanced renal cell carcinoma: systematic review and meta-analysis. Expert Opinion On Pharmacotherapy. 14: 27-39. PMID 23256638 DOI: 10.1517/14656566.2013.758713  0.058
2008 Chowdhury S, Larkin JM, Gore ME. Recent advances in the treatment of renal cell carcinoma and the role of targeted therapies. European Journal of Cancer (Oxford, England : 1990). 44: 2152-61. PMID 18829302 DOI: 10.1016/j.ejca.2008.06.028  0.058
2014 Mieda E, Wright SA, Larkin JE, Graham JR, Adkins SM, Lyke JE, Campbell RD, Maire J, Do T, Gordon J. Efficiency measurements and installation of a new grating for the OSIRIS spectrograph at keck observatory Publications of the Astronomical Society of the Pacific. 126: 250-263. DOI: 10.1086/675784  0.058
2016 Leuenberger W, Bearer S, Duchamp J, Johnson S, Leppo B, McElhenny P, Larkin J. A Comparison of Lepidoptera Communities Inhabiting Restored and Late Successional Pitch Pine-Scrub Oak Barrens in Pennsylvania Natural Areas Journal. 36: 38-47. DOI: 10.3375/043.036.0109  0.058
2014 Long GV, Stroyakovskiy D, Gogas H, Levchenko E, de Braud F, Larkin J, Garbe C, Jouary T, Hauschild A, Grob JJ, Chiarion Sileni V, Lebbe C, Mandalà M, Millward M, Arance A, et al. Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma. The New England Journal of Medicine. 371: 1877-88. PMID 25265492 DOI: 10.1056/NEJMoa1406037  0.057
2015 Yousaf N, Davidson M, Goode E, Thomas C, Hung R, Gore M, Larkin J. The cost of ipilimumab toxicity: a single-centre analysis. Melanoma Research. 25: 259-64. PMID 25860328 DOI: 10.1097/CMR.0000000000000158  0.057
2012 Larkin J, Esser N, Calvo E, Tsuchihashi Z, Fiedler U, Graeser R, Kim D. Efficacy of sequential treatment with sunitinib-everolimus in an orthotopic mouse model of renal cell carcinoma. Anticancer Research. 32: 2399-406. PMID 22753696  0.057
2012 Larkin JR, Zhang F, Godfrey L, Molostvov G, Zehnder D, Rabbani N, Thornalley PJ. Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes. Plos One. 7: e53175. PMID 23285265 DOI: 10.1371/journal.pone.0053175  0.057
2014 McArthur GA, Chapman PB, Robert C, Larkin J, Haanen JB, Dummer R, Ribas A, Hogg D, Hamid O, Ascierto PA, Garbe C, Testori A, Maio M, Lorigan P, Lebbé C, et al. Safety and efficacy of vemurafenib in BRAF(V600E) and BRAF(V600K) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study. The Lancet. Oncology. 15: 323-32. PMID 24508103 DOI: 10.1016/S1470-2045(14)70012-9  0.057
2013 Bedoya SK, Wilson TD, Collins EL, Lau K, Larkin J. Isolation and th17 differentiation of naïve CD4 T lymphocytes. Journal of Visualized Experiments : Jove. e50765. PMID 24121559 DOI: 10.3791/50765  0.057
2011 Bex A, Larkin J, Blank C. Non-clear cell renal cell carcinoma: how new biological insight may lead to new therapeutic modalities. Current Oncology Reports. 13: 240-8. PMID 21298371 DOI: 10.1007/s11912-011-0159-y  0.057
2009 Larkin JC. Morphological evolution: by any means necessary? Current Biology : Cb. 19: R953-4. PMID 19889373 DOI: 10.1016/j.cub.2009.09.002  0.056
2013 Henrion M, Frampton M, Scelo G, Purdue M, Ye Y, Broderick P, Ritchie A, Kaplan R, Meade A, McKay J, Johansson M, Lathrop M, Larkin J, Rothman N, Wang Z, et al. Common variation at 2q22.3 (ZEB2) influences the risk of renal cancer. Human Molecular Genetics. 22: 825-31. PMID 23184150 DOI: 10.1093/Hmg/Dds489  0.056
2015 Diem S, Kasenda B, Martin-Liberal J, Lee A, Chauhan D, Gore M, Larkin J. Prognostic score for patients with advanced melanoma treated with ipilimumab. European Journal of Cancer (Oxford, England : 1990). PMID 26597444 DOI: 10.1016/j.ejca.2015.09.007  0.055
2015 Miller RE, Tran PB, Ishihara S, Larkin J, Malfait AM. Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. PMID 26410555 DOI: 10.1016/j.joca.2015.09.005  0.055
2007 Larkin JO, Collins CG, Aarons S, Tangney M, Whelan M, O'Reily S, Breathnach O, Soden DM, O'Sullivan GC. Electrochemotherapy: aspects of preclinical development and early clinical experience. Annals of Surgery. 245: 469-79. PMID 17435555 DOI: 10.1097/01.sla.0000250419.36053.33  0.055
2014 Wang Y, Bu F, Royer C, Serres S, Larkin JR, Soto MS, Sibson NR, Salter V, Fritzsche F, Turnquist C, Koch S, Zak J, Zhong S, Wu G, Liang A, et al. ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1. Nature Cell Biology. 16: 1092-104. PMID 25344754 DOI: 10.1038/Ncb3050  0.055
2016 Motzer RJ, Hutson TE, Ren M, Dutcus C, Larkin J. Independent assessment of lenvatinib plus everolimus in patients with metastatic renal cell carcinoma. The Lancet. Oncology. 17: e4-5. PMID 26758760 DOI: 10.1016/S1470-2045(15)00543-4  0.055
2011 Lau K, Benitez P, Ardissone A, Wilson TD, Collins EL, Lorca G, Li N, Sankar D, Wasserfall C, Neu J, Atkinson MA, Shatz D, Triplett EW, Larkin J. Inhibition of type 1 diabetes correlated to a Lactobacillus johnsonii N6.2-mediated Th17 bias. Journal of Immunology (Baltimore, Md. : 1950). 186: 3538-46. PMID 21317395 DOI: 10.4049/Jimmunol.1001864  0.055
2011 Vasudev NS, Larkin JM. Tyrosine kinase inhibitors in the treatment of advanced renal cell carcinoma: focus on pazopanib. Clinical Medicine Insights. Oncology. 5: 333-42. PMID 22084622 DOI: 10.4137/CMO.S7263  0.055
2015 Kanu N, Grönroos E, Martinez P, Burrell RA, Yi Goh X, Bartkova J, Maya-Mendoza A, Mistrík M, Rowan AJ, Patel H, Rabinowitz A, East P, Wilson G, Santos CR, McGranahan N, ... ... Larkin J, et al. SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. Oncogene. PMID 25728682 DOI: 10.1038/Onc.2015.24  0.055
2010 Srinivas SK, Larkin J, Sammel MD, Appleby D, Bastek J, Andrela CM, Ofori E, Elovitz MA. The use of angiogenic factors in discriminating preeclampsia: are they ready for prime time? The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 23: 1294-300. PMID 20482287 DOI: 10.3109/14767051003677988  0.055
2015 Bex A, Larkin J, Voss M. Challenging the treatment paradigm for advanced renal cell carcinoma: a review of systemic and localized therapies. American Society of Clinical Oncology Educational Book / Asco. American Society of Clinical Oncology. Meeting. 35: e239-47. PMID 25993179 DOI: 10.14694/EdBook_AM.2015.35.e239  0.055
2009 Egan AM, Larkin JO, Ryan RS, Waldron R. Bilateral adrenal haemorrhage secondary to intra-abdominal sepsis: a case report. Cases Journal. 2: 6894. PMID 19829879 DOI: 10.4076/1757-1626-2-6894  0.054
2009 Larkin J, Bandi MM, Pumir A, Goldburg WI. Power-law distributions of particle concentration in free-surface flows. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 80: 066301. PMID 20365261 DOI: 10.1103/PhysRevE.80.066301  0.054
2013 Martinez P, Birkbak NJ, Gerlinger M, McGranahan N, Burrell RA, Rowan AJ, Joshi T, Fisher R, Larkin J, Szallasi Z, Swanton C. Parallel evolution of tumour subclones mimics diversity between tumours. The Journal of Pathology. 230: 356-64. PMID 23716380 DOI: 10.1002/Path.4214  0.054
2015 Kovac M, Navas C, Horswell S, Salm M, Bardella C, Rowan A, Stares M, Castro-Giner F, Fisher R, de Bruin EC, Kovacova M, Gorman M, Makino S, Williams J, Jaeger E, ... ... Larkin J, et al. Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution. Nature Communications. 6: 6336. PMID 25790038 DOI: 10.1038/Ncomms7336  0.054
2014 Germaschewski FM, Matheny CJ, Larkin J, Liu F, Thomas LR, Saunders JS, Sully K, Whittall C, Boyle Y, Peters G, Graham NM. Quantitation OF ARGS aggrecan fragments in synovial fluid, serum and urine from osteoarthritis patients. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 22: 690-7. PMID 24583346 DOI: 10.1016/j.joca.2014.02.930  0.054
2013 Turajlic S, Ali Z, Yousaf N, Larkin J. Phase I/II RAF kinase inhibitors in cancer therapy. Expert Opinion On Investigational Drugs. 22: 739-49. PMID 23642225 DOI: 10.1517/13543784.2013.797964  0.054
2012 Schmidinger M, Larkin J, Ravaud A. Experience with sunitinib in the treatment of metastatic renal cell carcinoma. Therapeutic Advances in Urology. 4: 253-65. PMID 23024706 DOI: 10.1177/1756287212454933  0.054
2010 Larkin JW, Binks SL, Li Y, Selvage D. The role of oestradiol in sexually dimorphic hypothalamic-pituitary-adrena axis responses to intracerebroventricular ethanol administration in the rat. Journal of Neuroendocrinology. 22: 24-32. PMID 19912475 DOI: 10.1111/j.1365-2826.2009.01934.x  0.054
2011 McArdle A, Larkin JO, Awan FN, McCormick PH, Mehigan BJ. Large-bowel obstruction secondary to urinary retention. Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland. 13: e160-1. PMID 21564469 DOI: 10.1111/j.1463-1318.2011.02553.x  0.054
2012 Thway K, du Parcq J, Larkin JM, Fisher C, Livni N. Metastatic renal mucinous tubular and spindle cell carcinoma. Atypical behavior of a rare, morphologically bland tumor. Annals of Diagnostic Pathology. 16: 407-10. PMID 21684183 DOI: 10.1016/j.anndiagpath.2011.04.001  0.054
2009 Pickering LM, Pyle L, Larkin JM. Sunitinib is superior to interferon alpha with respect to quality of life for patients with renal cell carcinoma. Nature Clinical Practice. Oncology. 6: 6-7. PMID 19096396 DOI: 10.1038/ncponc1283  0.053
2007 Larkin JM, Kaye SB. Potential clinical applications of epothilones: a review of phase II studies. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 18: v28-34. PMID 17656559 DOI: 10.1093/annonc/mdm176  0.053
2014 Sheehan J, Wood PB, Buehler DA, Keyser PD, Larkin JL, Rodewald AD, Wigley TB, Boves TJ, George GA, Bakermans MH, Beachy TA, Evans A, McDermott ME, Newell FL, Perkins KA, et al. Avian response to timber harvesting applied experimentally to manage Cerulean Warbler breeding populations Forest Ecology and Management. 321: 5-18. DOI: 10.1016/J.Foreco.2013.07.037  0.053
2007 Guay HM, Larkin J, Picca CC, Panarey L, Caton AJ. Spontaneous autoreactive memory B cell formation driven by a high frequency of autoreactive CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 4793-802. PMID 17404260 DOI: 10.4049/Jimmunol.178.8.4793  0.053
2015 Millar-Blanchaer MA, Graham JR, Pueyo L, Kalas P, Dawson RI, Wang J, Perrin MD, Moon DS, Macintosh B, Ammons SM, Barman T, Cardwell A, Chen CH, Chiang E, Chilcote J, ... Larkin JE, et al. β PICTORIS' INNER DISK in POLARIZED LIGHT and NEW ORBITAL PARAMETERS for β PICTORIS b Astrophysical Journal. 811. DOI: 10.1088/0004-637X/811/1/18  0.053
2014 Meyer E, Chen S, Wright SA, Moore AM, Larkin JE, Simard L, Marie J, Mieda E, Gordon J. The infrared imaging spectrograph (IRIS) for TMT: Reflective ruled diffraction grating performance testing and discussion Proceedings of Spie - the International Society For Optical Engineering. 9147. DOI: 10.1117/12.2056839  0.053
2015 Wang JJ, Graham JR, Pueyo L, Nielsen EL, Millar-Blanchaer M, Rosa RJD, Kalas P, Ammons SM, Bulger J, Cardwell A, Chen C, Chiang E, Chilcote JK, Doyon R, Draper ZH, ... Larkin JE, et al. Gemini planet imager observations of the au microscopii debris disk: Asymmetries within one arcsecond Astrophysical Journal Letters. 811. DOI: 10.1088/2041-8205/811/2/L19  0.053
2015 Al Chalabi H, Larkin J, Mehigan B, McCormick P. A systematic review of laparoscopic versus open abdominal incisional hernia repair, with meta-analysis of randomized controlled trials. International Journal of Surgery (London, England). 20: 65-74. PMID 26074289 DOI: 10.1016/j.ijsu.2015.05.050  0.053
2012 Fisher R, Larkin J, Swanton C. Inter and intratumour heterogeneity: a barrier to individualized medical therapy in renal cell carcinoma? Frontiers in Oncology. 2: 49. PMID 22655275 DOI: 10.3389/Fonc.2012.00049  0.053
2011 Bhat KL, Markham GD, Larkin JD, Bock CW. Thermodynamics of boroxine formation from the aliphatic boronic acid monomers R-B(OH)2 (R = H, H3C, H2N, HO, and F): a computational investigation. The Journal of Physical Chemistry. A. 115: 7785-93. PMID 21650154 DOI: 10.1021/jp202409m  0.053
2014 Larkin J, Henley RY, Muthukumar M, Rosenstein JK, Wanunu M. High-bandwidth protein analysis using solid-state nanopores. Biophysical Journal. 106: 696-704. PMID 24507610 DOI: 10.1016/J.Bpj.2013.12.025  0.052
2015 Ahmed CM, Dabelic R, Bedoya SK, Larkin J, Johnson HM. A SOCS1/3 Antagonist Peptide Protects Mice Against Lethal Infection with Influenza A Virus. Frontiers in Immunology. 6: 574. PMID 26617608 DOI: 10.3389/Fimmu.2015.00574  0.052
2015 Henrion MY, Purdue MP, Scelo G, Broderick P, Frampton M, Ritchie A, Meade A, Li P, McKay J, Johansson M, Lathrop M, Larkin J, Rothman N, Wang Z, Chow WH, et al. Common variation at 1q24.1 (ALDH9A1) is a potential risk factor for renal cancer. Plos One. 10: e0122589. PMID 25826619 DOI: 10.1371/Journal.Pone.0122589  0.052
2014 Hutson TE, Bukowski RM, Rini BI, Gore ME, Larkin JM, Figlin RA, Barrios CH, Escudier B, Lin X, Fly K, Martell B, Matczak E, Motzer RJ. Efficacy and safety of sunitinib in elderly patients with metastatic renal cell carcinoma. British Journal of Cancer. 110: 1125-32. PMID 24434434 DOI: 10.1038/bjc.2013.832  0.052
2013 O'Farrell NJ, Reynolds JV, Ravi N, Larkin JO, Malik V, Wilson GF, Muldoon C, O'Toole D. Evolving changes in the management of early oesophageal adenocarcinoma in a tertiary centre. Irish Journal of Medical Science. 182: 363-9. PMID 23242575 DOI: 10.1007/s11845-012-0890-x  0.052
2007 Larkin JM, Chowdhury S, Gore ME. Drug insight: advances in renal cell carcinoma and the role of targeted therapies. Nature Clinical Practice. Oncology. 4: 470-9. PMID 17657252 DOI: 10.1038/ncponc0901  0.051
2008 Larkin JD, Milkevitch M, Bhat KL, Markham GD, Brooks BR, Bock CW. Dimers of boroglycine and methylamine boronic acid: a computational comparison of the relative importance of dative versus hydrogen bonding. The Journal of Physical Chemistry. A. 112: 125-33. PMID 18072757 DOI: 10.1021/Jp076537H  0.051
2007 Hollingsworth JW, Whitehead G, Berman KG, Tekippe EM, Gilmour MI, Larkin JE, Quackenbush J, Schwartz DA. Genetic basis of murine antibacterial defense to streptococcal lung infection. Immunogenetics. 59: 713-24. PMID 17701033 DOI: 10.1007/S00251-007-0242-6  0.051
2012 Deng H, O'Keefe H, Davie CP, Lind KE, Acharya RA, Franklin GJ, Larkin J, Matico R, Neeb M, Thompson MM, Lohr T, Gross JW, Centrella PA, O'Donovan GK, Bedard KL, et al. Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT). Journal of Medicinal Chemistry. 55: 7061-79. PMID 22891645 DOI: 10.1021/Jm300449X  0.051
2014 Maigret TA, Cox JJ, Schneider DR, Barton CD, Price SJ, Larkin JL. Effects of timber harvest within streamside management zones on salamander populations in ephemeral streams of southeastern Kentucky Forest Ecology and Management. 324: 46-51. DOI: 10.1016/J.Foreco.2014.03.043  0.051
2012 Sinha R, Edmonds K, Newton-Bishop JA, Gore ME, Larkin J, Fearfield L. Cutaneous adverse events associated with vemurafenib in patients with metastatic melanoma: practical advice on diagnosis, prevention and management of the main treatment-related skin toxicities. The British Journal of Dermatology. 167: 987-94. PMID 22913467 DOI: 10.1111/bjd.12010  0.051
2006 Larkin JM, Eisen T. Kinase inhibitors in the treatment of renal cell carcinoma. Critical Reviews in Oncology/Hematology. 60: 216-26. PMID 16860997 DOI: 10.1016/j.critrevonc.2006.06.008  0.051
2015 Martin-Liberal J, Furness AJ, Joshi K, Peggs KS, Quezada SA, Larkin J. Anti-programmed cell death-1 therapy and insulin-dependent diabetes: a case report. Cancer Immunology, Immunotherapy : Cii. 64: 765-7. PMID 25828465 DOI: 10.1007/s00262-015-1689-1  0.05
2012 Khattak MA, Fisher RA, Pickering LM, Gore ME, Larkin JM. Endobronchial metastases from renal cell carcinoma: a late manifestation of the disease with an increasing incidence. Bju International. 110: 1407-8. PMID 22937754 DOI: 10.1111/j.1464-410X.2012.11442.x  0.05
2012 Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, Martinez P, Matthews N, Stewart A, Tarpey P, Varela I, Phillimore B, Begum S, McDonald NQ, Butler A, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. The New England Journal of Medicine. 366: 883-92. PMID 22397650 DOI: 10.1056/Nejmoa1113205  0.05
2015 Tevlin R, Larkin JO, Hyland JM, O'Connell PR, Winter DC. Primary colorectal lymphoma - A single centre experience. The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 13: 151-5. PMID 24694573 DOI: 10.1016/j.surge.2014.01.002  0.05
2014 Skinner GE, Marshall KM, Morrissey TR, Loeza V, Patazca E, Reddy NR, Larkin JW. Combined high pressure and thermal processing on inactivation of type E and nonproteolytic type B and F spores of Clostridium botulinum. Journal of Food Protection. 77: 2054-61. PMID 25474050 DOI: 10.4315/0362-028X.JFP-14-259  0.05
2012 Larkin JO, O'Connell PR. Multivisceral resection for T4 or recurrent colorectal cancer. Digestive Diseases (Basel, Switzerland). 30: 96-101. PMID 23207940 DOI: 10.1159/000342037  0.049
2007 Wakabayashi Y, Chua J, Larkin JM, Lippincott-Schwartz J, Arias IM. Four-dimensional imaging of filter-grown polarized epithelial cells. Histochemistry and Cell Biology. 127: 463-72. PMID 17308935 DOI: 10.1007/S00418-007-0274-X  0.049
2014 Larkin JC, Sears SB, Sadovsky Y. The influence of ligand-activated LXR on primary human trophoblasts. Placenta. 35: 919-24. PMID 25255963 DOI: 10.1016/j.placenta.2014.09.002  0.049
2008 Carden CP, Larkin JM, Rosenthal MA. What is the risk of intracranial bleeding during anti-VEGF therapy? Neuro-Oncology. 10: 624-30. PMID 18539884 DOI: 10.1215/15228517-2008-010  0.049
2014 Baker P, Davies SL, Larkin J, Moult D, Benton S, Roberts A, Harris T. Changes to the cardiac biomarkers of non-elite athletes completing the 2009 London Marathon. Emergency Medicine Journal : Emj. 31: 374-9. PMID 23513235 DOI: 10.1136/emermed-2012-201465  0.049
2013 Fearfield L, Newton-Bishop JA, Sinha R, Edmonds K, Gore ME, Larkin J. Second primary melanomas on treatment with vemurafenib: reply from the authors. The British Journal of Dermatology. 168: 888-9. PMID 23066884 DOI: 10.1111/bjd.12094  0.049
2011 Larkin JL, Gabriel M, Gerhold RW, Yabsley MJ, Wester JC, Humphreys JG, Beckstead R, Dubey JP. Prevalence to Toxoplasma gondii and Sarcocystis spp. in a reintroduced fisher (Martes pennanti) population in Pennsylvania. The Journal of Parasitology. 97: 425-9. PMID 21506854 DOI: 10.1645/Ge-2623.1  0.048
2014 Larkin JO, Moriarity AR, Cooke F, McCormick PH, Mehigan BJ. Self-expanding metal stent insertion by colorectal surgeons in the management of obstructing colorectal cancers: a 6-year experience. Techniques in Coloproctology. 18: 453-8. PMID 24114608 DOI: 10.1007/s10151-013-1073-0  0.048
2012 Larkin J, Goh XY, Vetter M, Pickering L, Swanton C. Epigenetic regulation in RCC: opportunities for therapeutic intervention? Nature Reviews. Urology. 9: 147-55. PMID 22249190 DOI: 10.1038/Nrurol.2011.236  0.048
2015 Kasenda B, Larkin J, Gore M. Immunotherapies in Early and Advanced Renal Cell Cancer. Progress in Tumor Research. 42: 1-10. PMID 26376844 DOI: 10.1159/000436988  0.048
2012 Larkin JD, Cook PR. Maximum precision closed-form solution for localizing diffraction-limited spots in noisy images. Optics Express. 20: 18478-93. PMID 23038398 DOI: 10.1364/Oe.20.018478  0.048
2014 Tevlin R, Cahalane AM, Larkin JO, Treacy A, Connaghan D, Winter DC. Gastrointestinal Erdheim-Chester disease. Irish Medical Journal. 107: 149-50. PMID 24908861  0.048
2009 Miller RE, Larkin JM. Combination systemic therapy for advanced renal cell carcinoma. The Oncologist. 14: 1218-24. PMID 19939892 DOI: 10.1634/theoncologist.2009-0105  0.048
2011 Gore ME, Larkin JM. Challenges and opportunities for converting renal cell carcinoma into a chronic disease with targeted therapies. British Journal of Cancer. 104: 399-406. PMID 21285971 DOI: 10.1038/sj.bjc.6606084  0.047
2013 Patazca E, Morrissey TR, Loeza V, Reddy NR, Skinner GE, Larkin JW. Effect of packaging systems and pressure fluids on inactivation of Clostridium botulinum spores by combined high pressure and thermal processing. Journal of Food Protection. 76: 448-55. PMID 23462082 DOI: 10.4315/0362-028X.JFP-12-181  0.047
2006 Fiegler H, Redon R, Andrews D, Scott C, Andrews R, Carder C, Clark R, Dovey O, Ellis P, Feuk L, French L, Hunt P, Kalaitzopoulos D, Larkin J, Montgomery L, et al. Accurate and reliable high-throughput detection of copy number variation in the human genome. Genome Research. 16: 1566-74. PMID 17122085 DOI: 10.1101/Gr.5630906  0.047
2014 Do T, Wright SA, Barth AJ, Barton EJ, Simard L, Larkin JE, Moore AM, Wang L, Ellerbroek B. Prospects for measuring supermassive black hole masses with future extremely large telescopes Astronomical Journal. 147. DOI: 10.1088/0004-6256/147/4/93  0.047
2014 Larkin J. Advances in treating solid tumors Clinical Practice. 11: 145-147. DOI: 10.2217/cpr.13.92  0.047
2009 Hensley ML, Ishill N, Soslow R, Larkin J, Abu-Rustum N, Sabbatini P, Konner J, Tew W, Spriggs D, Aghajanian CA. Adjuvant gemcitabine plus docetaxel for completely resected stages I-IV high grade uterine leiomyosarcoma: Results of a prospective study. Gynecologic Oncology. 112: 563-7. PMID 19135708 DOI: 10.1016/j.ygyno.2008.11.027  0.047
2014 Ascierto PA, Grimaldi AM, Anderson AC, Bifulco C, Cochran A, Garbe C, Eggermont AM, Faries M, Ferrone S, Gershenwald JE, Gajewski TF, Halaban R, Hodi FS, Kefford R, Kirkwood JM, ... Larkin J, et al. Future perspectives in melanoma research: meeting report from the "Melanoma Bridge", Napoli, December 5th-8th 2013. Journal of Translational Medicine. 12: 277. PMID 25348889 DOI: 10.1186/s12967-014-0277-z  0.046
2011 Josephs D, Hutson TE, Cowey CL, Pickering LM, Larkin JM, Gore ME, Van Hemelrijck M, McDermott DF, Powles T, Chowdhury P, Karapetis C, Harper PG, Choueiri TK, Chowdhury S. Efficacy and toxicity of sunitinib in patients with metastatic renal cell carcinoma with severe renal impairment or on haemodialysis. Bju International. 108: 1279-83. PMID 21244613 DOI: 10.1111/j.1464-410X.2010.09990.x  0.046
2012 Timbie JW, Ringel JS, Fox DS, Waxman DA, Pillemer F, Carey C, Moore M, Karir V, Johnson TJ, Iyer N, Hu J, Shanman R, Larkin JW, Timmer M, Motala A, et al. Allocation of scarce resources during mass casualty events. Evidence Report/Technology Assessment. 1-305. PMID 24422904  0.046
2013 Vasudev NS, Goh V, Juttla JK, Thompson VL, Larkin JM, Gore M, Nathan PD, Reynolds AR. Changes in tumour vessel density upon treatment with anti-angiogenic agents: relationship with response and resistance to therapy. British Journal of Cancer. 109: 1230-42. PMID 23922108 DOI: 10.1038/bjc.2013.429  0.046
2016 Diem S, Kasenda B, Spain L, Martin-Liberal J, Marconcini R, Gore M, Larkin J. Serum lactate dehydrogenase as an early marker for outcome in patients treated with anti-PD-1 therapy in metastatic melanoma British Journal of Cancer. 114: 256-261. DOI: 10.1038/bjc.2015.467  0.046
2010 Valladares R, Sankar D, Li N, Williams E, Lai KK, Abdelgeliel AS, Gonzalez CF, Wasserfall CH, Larkin J, Schatz D, Atkinson MA, Triplett EW, Neu J, Lorca GL. Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats. Plos One. 5: e10507. PMID 20463897 DOI: 10.1371/Journal.Pone.0010507  0.046
2014 Bao D, Upadhyayula S, Larsen JM, Xia B, Georgieva B, Nuñez V, Espinoza EM, Hartman JD, Wurch M, Chang A, Lin CK, Larkin J, Vasquez K, Beran GJ, Vullev VI. Dipole-mediated rectification of intramolecular photoinduced charge separation and charge recombination. Journal of the American Chemical Society. 136: 12966-73. PMID 25162490 DOI: 10.1021/Ja505618N  0.046
2010 Larkin JM, Pyle LM, Gore ME. Fatigue in renal cell carcinoma: the hidden burden of current targeted therapies. The Oncologist. 15: 1135-46. PMID 21051659 DOI: 10.1634/theoncologist.2010-0078  0.045
2015 Larkin J, Lohr TA, Elefante L, Shearin J, Matico R, Su JL, Xue Y, Liu F, Genell C, Miller RE, Tran PB, Malfait AM, Maier CC, Matheny CJ. Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. PMID 25800415 DOI: 10.1016/j.joca.2015.02.778  0.045
2015 Rao NZ, Larkin JD, Bock CW. A comparison of the structure and bonding in the aliphatic boronic R–B(OH)2 and borinic R–BH(OH) acids (R=H; NH2, OH, and F): a computational investigation Structural Chemistry. 1-11. DOI: 10.1007/s11224-015-0730-5  0.045
2010 Larkin JO, Bourke MG, Muhammed A, Waldron R, Barry K, Eustace PW. Mortality in perforated duodenal ulcer depends upon pre-operative risk: a retrospective 10-year study. Irish Journal of Medical Science. 179: 545-9. PMID 20589448 DOI: 10.1007/s11845-010-0515-1  0.044
2014 Gulati S, Martinez P, Joshi T, Birkbak NJ, Santos CR, Rowan AJ, Pickering L, Gore M, Larkin J, Szallasi Z, Bates PA, Swanton C, Gerlinger M. Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkers. European Urology. 66: 936-48. PMID 25047176 DOI: 10.1016/J.Eururo.2014.06.053  0.044
2015 Gulati S, Turajlic S, Larkin J, Bates PA, Swanton C. Relapse models for clear cell renal carcinoma. The Lancet. Oncology. 16: e376-8. PMID 26248843 DOI: 10.1016/S1470-2045(15)00090-X  0.044
2010 Larkin J, Gore M. Is advanced renal cell carcinoma becoming a chronic disease? Lancet. 376: 574-5. PMID 20728740 DOI: 10.1016/S0140-6736(10)60816-1  0.044
2015 Tevlin R, Larkin JO, Hyland JM, O'Connell PR, Winter DC. Brain metastasis from colorectal carcinoma: a single cancer centre experience. Irish Journal of Medical Science. PMID 25802245 DOI: 10.1007/s11845-015-1272-y  0.044
2015 Larkin J, Paine A, Foley G, Mitchell S, Chen C. First-line treatment in the management of advanced renal cell carcinoma: systematic review and network meta-analysis. Expert Opinion On Pharmacotherapy. 16: 1915-27. PMID 26194211 DOI: 10.1517/14656566.2015.1058359  0.044
2013 Richardson AJ, Tevlin R, Larkin JO, Beddy D. Seppuku: a modern approach to an ancient injury. Irish Medical Journal. 106: 211-2. PMID 24218749  0.044
2014 Sprouse C, Gordish-Dressman H, Orkunoglu-Suer EF, Lipof JS, Moeckel-Cole S, Patel RR, Adham K, Larkin JS, Hubal MJ, Kearns AK, Clarkson PM, Thompson PD, Angelopoulos TJ, Gordon PM, Moyna NM, et al. SLC30A8 nonsynonymous variant is associated with recovery following exercise and skeletal muscle size and strength. Diabetes. 63: 363-8. PMID 24101675 DOI: 10.2337/Db13-1150  0.044
2014 Al Chalabi H, O'Riordan JM, Richardson A, Flannery D, O'Connor K, Stuart C, Larkin J, McCormick P, Mehigan B. Six-year experience of a nurse-led colorectal cancer follow-up clinic. Surgery Research and Practice. 2014: 368060. PMID 25374950 DOI: 10.1155/2014/368060  0.044
2015 Medling AM, Vivian U, Max CE, Sanders DB, Armus L, Holden B, Mieda E, Wright SA, Larkin JE. Following black hole scaling relations through gas-rich mergers Astrophysical Journal. 803. DOI: 10.1088/0004-637X/803/2/61  0.044
2013 Shi XH, Larkin JC, Chen B, Sadovsky Y. The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts. Plos One. 8: e75473. PMID 24066183 DOI: 10.1371/journal.pone.0075473  0.043
2013 Yousaf N, Larkin J. Axitinib in advanced renal-cell carcinoma. The Lancet. Oncology. 14: 1245-6. PMID 24206641 DOI: 10.1016/S1470-2045(13)70499-6  0.043
2014 Martin-Liberal J, Lagares-Tena L, Larkin J. Prospects for MEK inhibitors for treating cancer. Expert Opinion On Drug Safety. 13: 483-95. PMID 24597490 DOI: 10.1517/14740338.2014.892578  0.043
2015 Bakermans MH, Smith BW, Jones BC, Larkin JL. Stand and within-stand factors influencing golden-winged warbler use of regenerating stands the central appalachian mountains | Caractéristiques de peuplements et intra-peuplements ayant une influence sur l'utilisation de peuplements en régénération par la Paruline à ailes dorées dans le secteur centre des Appalaches Avian Conservation and Ecology. 10. DOI: 10.5751/Ace-00747-100110  0.043
2015 Larkin J, Hodi FS, Wolchok JD. Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma. The New England Journal of Medicine. 373: 1270-1. PMID 26398076 DOI: 10.1056/NEJMc1509660  0.042
2012 Bock CW, Larkin JD. Heats of Formation for the Boronic Acids R-B(OH)2 and Boroxines R3B3O3 (R=H, Li, HBe, H2B, H3C, H2N, HO, F, and Cl) Calculated at the G2, G3, and G4 Levels of Theory. Computational & Theoretical Chemistry. 986: 35-42. PMID 24653975 DOI: 10.1016/j.comptc.2012.02.007  0.042
2010 Reynolds JV, Ravi N, Muldoon C, Larkin JO, Rowley S, O'Byrne K, Hollywood D, O'Toole D. Differential pathologic variables and outcomes across the spectrum of adenocarcinoma of the esophagogastric junction. World Journal of Surgery. 34: 2821-9. PMID 20827475 DOI: 10.1007/s00268-010-0783-y  0.042
2012 Larkin JC, Hill LM, Speer PD, Simhan HN. Risk of morbid perinatal outcomes in small-for-gestational-age pregnancies: customized compared with conventional standards of fetal growth. Obstetrics and Gynecology. 119: 21-7. PMID 22183207 DOI: 10.1097/AOG.0b013e31823dc56e  0.041
2012 Larkin JM, Fisher RA, Gore ME. Adjuvant interferon therapy for patients at high risk for recurrent melanoma: an updated systematic review. Clinical Oncology (Royal College of Radiologists (Great Britain)). 24: 410-2. PMID 22521078 DOI: 10.1016/j.clon.2012.03.010  0.041
2012 dela Torre R, Larkin J, Singer A, Meller A. Fabrication and characterization of solid-state nanopore arrays for high-throughput DNA sequencing. Nanotechnology. 23: 385308. PMID 22948520 DOI: 10.1088/0957-4484/23/38/385308  0.041
2009 Larkin JO, Thekiso TB, Waldron R, Barry K, Eustace PW. Recurrent sigmoid volvulus - early resection may obviate later emergency surgery and reduce morbidity and mortality. Annals of the Royal College of Surgeons of England. 91: 205-9. PMID 19335969 DOI: 10.1308/003588409X391776  0.041
2008 Larkin JO, Cullen IM, Kelleher MO, Fitzgibbon J, Keohane K, O'Sullivan MG, Rogers E. Transitional cell carcinoma of the upper ureter metastatic to the thoracic spine presenting as a spinal cord compression. Thescientificworldjournal. 8: 223-7. PMID 18335148 DOI: 10.1100/tsw.2008.43  0.041
2012 Tao P, Hodoš?ek M, Larkin JD, Shao Y, Brooks BR. Comparison of Three Chain-of-States Methods: Nudged Elastic Band and Replica Path with Restraints or Constraints. Journal of Chemical Theory and Computation. 8: 5035-5051. PMID 23526888 DOI: 10.1021/Ct3006248  0.041
2011 Larkin JO, Awan FN, McArdle AC, McCormick PH, Mehigan BJ. Partial herniation through the peritoneal defect of a pfannenstiel incision: a rare complication of non-closure. Journal of Obstetrics and Gynaecology Canada : Jogc = Journal D'Obstã©Trique Et Gynã©Cologie Du Canada : Jogc. 33: 625-7. PMID 21846453  0.04
2015 Sinha R, Larkin J, Fearfield L. Clinical resolution of vemurafenib-induced squamous cell carcinoma with topical 5-fluorouracil. The British Journal of Dermatology. 172: 1135-6. PMID 25234953 DOI: 10.1111/bjd.13415  0.04
2012 Fisher R, Larkin J. Treatment of brain metastases in patients with melanoma. The Lancet. Oncology. 13: 434-5. PMID 22456430 DOI: 10.1016/S1470-2045(12)70118-3  0.039
2012 Thorneloe KS, Cheung M, Bao W, Alsaid H, Lenhard S, Jian MY, Costell M, Maniscalco-Hauk K, Krawiec JA, Olzinski A, Gordon E, Lozinskaya I, Elefante L, Qin P, Matasic DS, ... ... Larkin J, et al. An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure. Science Translational Medicine. 4: 159ra148. PMID 23136043 DOI: 10.1126/Scitranslmed.3004276  0.039
2014 Furney SJ, Turajlic S, Stamp G, Thomas JM, Hayes A, Strauss D, Gavrielides M, Xing W, Gore M, Larkin J, Marais R. The mutational burden of acral melanoma revealed by whole-genome sequencing and comparative analysis. Pigment Cell & Melanoma Research. 27: 835-8. PMID 24913711 DOI: 10.1111/pcmr.12279  0.039
2013 Mohan HM, Evans MD, Larkin JO, Beynon J, Winter DC. Multivisceral resection in colorectal cancer: a systematic review. Annals of Surgical Oncology. 20: 2929-36. PMID 23666095 DOI: 10.1245/s10434-013-2967-9  0.039
2015 Rao NZ, Larkin JD, Bock CW. A computational investigation of monosubstituted boroxines(RH2B3O3): structure and formation Structural Chemistry. DOI: 10.1007/S11224-015-0577-9  0.039
2007 Larkin J, Picca CC, Caton AJ. Activation of CD4+ CD25+ regulatory T cell suppressor function by analogs of the selecting peptide. European Journal of Immunology. 37: 139-46. PMID 17154263 DOI: 10.1002/Eji.200636577  0.039
2005 Larkin JO, Collins CG, Martin ST, Kalimuthu S, Fitzgibbon J, Lee G, O'Sullivan GC. Paraesophageal lymph node metastasis from prostatic adenocarcinoma in a patient with esophageal squamous carcinoma. Diseases of the Esophagus : Official Journal of the International Society For Diseases of the Esophagus / I.S.D.E. 18: 124-6. PMID 16053489 DOI: 10.1111/j.1442-2050.2005.00459.x  0.039
2012 Khattak M, Gore M, Larkin J, Strauss D, Thomas M, Hayes A, Harrington K. Adjuvant nodal irradiation in melanoma. The Lancet. Oncology. 13: e326-7; author reply. PMID 22846833 DOI: 10.1016/S1470-2045(12)70295-4  0.039
2013 Lacourse S, Rybak N, Lewis C, Gartman J, Larkin J, McLaughlin S, Toll ET. Health screening of newly resettled refugees in a primary care setting. Rhode Island Medical Journal (2013). 96: 28-32. PMID 23641449  0.039
2014 Joubert W, Archibald R, Berrill M, Michael Brown W, Eisenbach M, Grout R, Larkin J, Levesque J, Messer B, Norman M, Philip B, Sankaran R, Tharrington A, Turner J. Accelerated application development: The ORNL Titan experience Computers and Electrical Engineering. DOI: 10.1016/J.Compeleceng.2015.04.008  0.038
2008 Larkin J, Rankin AL, Picca CC, Riley MP, Jenks SA, Sant AJ, Caton AJ. CD4+CD25+ regulatory T cell repertoire formation shaped by differential presentation of peptides from a self-antigen. Journal of Immunology (Baltimore, Md. : 1950). 180: 2149-57. PMID 18250421 DOI: 10.4049/Jimmunol.180.4.2149  0.038
2011 Larkin JC, Speer PD, Simhan HN. A customized standard of large size for gestational age to predict intrapartum morbidity. American Journal of Obstetrics and Gynecology. 204: 499.e1-10. PMID 21514553 DOI: 10.1016/j.ajog.2011.02.068  0.038
2019 Clarke DJB, Wang L, Jones A, Wojciechowicz ML, Torre D, Jagodnik KM, Jenkins SL, McQuilton P, Flamholz Z, Silverstein MC, Schilder BM, Robasky K, Castillo C, Idaszak R, Ahalt SC, ... ... Larkin J, et al. FAIRshake: Toolkit to Evaluate the FAIRness of Research Digital Resources. Cell Systems. PMID 31677972 DOI: 10.1016/J.Cels.2019.09.011  0.038
2013 O'Sullivan KE, Larkin JO, Guiney M, Reynolds JV. Necrotising pancreatitis presenting as a painful mass in the groin and sepsis. Bmj Case Reports. 2013. PMID 23625666 DOI: 10.1136/bcr-2013-008726  0.038
2014 Adkins SM, Armandroff TE, Fitzgerald MP, Johnson J, Larkin JE, Lewis HA, Martin C, Matthews KY, Prochaska JX, Wizinowich P. New developments in instrumentation at the W. M. Keck Observatory Proceedings of Spie - the International Society For Optical Engineering. 9147. DOI: 10.1117/12.2056971  0.038
2015 Larkin J. From EIB and SACE: € 600 million for FCA's research activities in Italy Automotive Industries Ai. 195.  0.038
2014 Ingraham P, Perrin MD, Sadakuni N, Ruffio JB, Maire J, Chilcote J, Larkin J, Marchis F, Galicher R, Weiss J. Gemini planet imager observational calibrations II: Detector performance and calibration Proceedings of Spie - the International Society For Optical Engineering. 9147. DOI: 10.1117/12.2057437  0.038
2015 Boves TJ, Rodewald AD, Wood PB, Buehler DA, Larkin JL, Wigley TB, Keyser PD. Habitat quality from individual- and population-level perspectives and implications for management Wildlife Society Bulletin. 39: 443-447. DOI: 10.1002/Wsb.528  0.038
2015 Pickering LM, Larkin J. Kidney cancer: Carbonic anhydrase IX in resected clear cell RCC. Nature Reviews. Urology. 12: 309-10. PMID 26032554 DOI: 10.1038/nrurol.2015.124  0.037
2012 Young K, Minchom A, Larkin J. BRIM-1, -2 and -3 trials: improved survival with vemurafenib in metastatic melanoma patients with a BRAF(V600E) mutation. Future Oncology (London, England). 8: 499-507. PMID 22646765 DOI: 10.2217/fon.12.43  0.037
2011 Larkin JD, Publicover NG, Sutko JL. Photon event distribution sampling: an image formation technique for scanning microscopes that permits tracking of sub-diffraction particles with high spatial and temporal resolutions. Journal of Microscopy. 241: 54-68. PMID 21118205 DOI: 10.1111/J.1365-2818.2010.03406.X  0.037
2009 Larkin JD, Markham GD, Milkevitch M, Brooks BR, Bock CW. Computational investigation of the oxidative deboronation of boroglycine, H2N-CH2-B(OH)2, Using H2O and H2O2. The Journal of Physical Chemistry. A. 113: 11028-34. PMID 19810757 DOI: 10.1021/Jp904149W  0.037
2010 Harmon BT, Orkunoglu-Suer EF, Adham K, Larkin JS, Gordish-Dressman H, Clarkson PM, Thompson PD, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Hubal MJ, Tosi LL, et al. CCL2 and CCR2 variants are associated with skeletal muscle strength and change in strength with resistance training. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 1779-85. PMID 20947712 DOI: 10.1152/Japplphysiol.00633.2010  0.037
2006 Picca CC, Larkin J, Boesteanu A, Lerman MA, Rankin AL, Caton AJ. Role of TCR specificity in CD4+ CD25+ regulatory T-cell selection. Immunological Reviews. 212: 74-85. PMID 16903907 DOI: 10.1111/J.0105-2896.2006.00416.X  0.037
2015 Bourne PE, Bonazzi V, Dunn M, Green ED, Guyer M, Komatsoulis G, Larkin J, Russell B. The NIH Big Data to Knowledge (BD2K) initiative. Journal of the American Medical Informatics Association : Jamia. 22: 1114. PMID 26555016 DOI: 10.1093/Jamia/Ocv136  0.037
2015 Aldinger KR, Terhune TM, Wood PB, Buehler DA, Bakermans MH, Confer JL, Flaspohler DJ, Larkin JL, Loegering JP, Percy KL, Roth AM, Smalling CG. Variables associated with nest survival of Golden-winged Warblers (Vermivora Chrysoptera) among vegetation communities commonly used for nesting | Variables associées á la survie des nids de Paruline á ailes dorées (Vermivora chrysoptera) parmi les communautés végétales fréquemment utilisées pour nicher Avian Conservation and Ecology. 10. DOI: 10.5751/Ace-00748-100106  0.036
2015 Bakermans MH, Ziegler CL, Larkin JL. American woodcock and golden-winged warbler abundance and associated vegetation in managed habitats Northeastern Naturalist. 22: 690-703. DOI: 10.1656/045.022.0405  0.036
2015 Froehlich R, Simhan HN, Larkin JC. An Evidence-Based Approach to Defining Fetal Macrosomia. American Journal of Perinatology. PMID 26499356 DOI: 10.1055/s-0035-1565998  0.036
2009 Rabbani N, Alam SS, Riaz S, Larkin JR, Akhtar MW, Shafi T, Thornalley PJ. High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study. Diabetologia. 52: 208-12. PMID 19057893 DOI: 10.1007/s00125-008-1224-4  0.036
2012 Larkin JO, Carroll PA, McCormick PH, Mehigan BJ. Control of splenic bleeding during splenic flexure mobilisation by devascularisation of the inferior pole of the spleen. Techniques in Coloproctology. 16: 459-61. PMID 22588241 DOI: 10.1007/s10151-012-0840-7  0.035
2014 Foulcer SJ, Nelson CM, Quintero MV, Kuberan B, Larkin J, Dours-Zimmermann MT, Zimmermann DR, Apte SS. Determinants of versican-V1 proteoglycan processing by the metalloproteinase ADAMTS5. The Journal of Biological Chemistry. 289: 27859-73. PMID 25122765 DOI: 10.1074/jbc.M114.573287  0.035
2005 Cozzo C, Lerman MA, Boesteanu A, Larkin J, Jordan MS, Caton AJ. Selection of CD4+CD25+ regulatory T cells by self-peptides. Current Topics in Microbiology and Immunology. 293: 3-23. PMID 15981473  0.035
2010 Larkin JD, Fossey JS, James TD, Brooks BR, Bock CW. A computational investigation of the nitrogen-boron interaction in o-(N,N-dialkylaminomethyl)arylboronate systems. The Journal of Physical Chemistry. A. 114: 12531-9. PMID 21050022 DOI: 10.1021/Jp1087674  0.035
2011 Minchom A, Young K, Larkin J. Ipilimumab: showing survival benefit in metastatic melanoma. Future Oncology (London, England). 7: 1255-64. PMID 22044200 DOI: 10.2217/fon.11.105  0.035
2010 Larkin J, Goldburg WI. Decorrelating a compressible turbulent flow: an experiment. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 82: 016301. PMID 20866719 DOI: 10.1103/PhysRevE.82.016301  0.035
2006 Larkin JM, Eisen T. Renal cell carcinoma and the use of sorafenib. Therapeutics and Clinical Risk Management. 2: 87-98. PMID 18360584  0.035
2013 Bedoya SK, Lam B, Lau K, Larkin J. Th17 cells in immunity and autoimmunity. Clinical & Developmental Immunology. 2013: 986789. PMID 24454481 DOI: 10.1155/2013/986789  0.034
2014 Ivankin A, Henley RY, Larkin J, Carson S, Toscano ML, Wanunu M. Label-free optical detection of biomolecular translocation through nanopore arrays. Acs Nano. 8: 10774-81. PMID 25232895 DOI: 10.1021/Nn504551D  0.034
2012 Fisher R, Cahalin P, Gore M, Larkin J. A tale of two tumours and a plea for progress. The Lancet. Oncology. 13: 124-5. PMID 22300855 DOI: 10.1016/S1470-2045(12)70005-0  0.034
2015 Argyropulo-Palmer M, Jenkins A, Theti DS, Larkin J, Montgomery D. Sunitinib in Metastatic Renal Cell Carcinoma: A Systematic Review of UK Real World Data. Frontiers in Oncology. 5: 195. PMID 26380224 DOI: 10.3389/fonc.2015.00195  0.034
2014 Kenny LM, Tomasi G, Turkheimer F, Larkin J, Gore M, Brock CS, Mangar S, Aboagye EO. Preliminary clinical assessment of the relationship between tumor alphavbeta3 integrin and perfusion in patients studied with [(18)F]fluciclatide kinetics and [ (15)O]H 2O PET. Ejnmmi Research. 4: 30. PMID 26055935 DOI: 10.1186/s13550-014-0030-x  0.033
2014 Dickens AM, Larkin JR, Griffin JL, Cavey A, Matthews L, Turner MR, Wilcock GK, Davis BG, Claridge TD, Palace J, Anthony DC, Sibson NR. A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis. Neurology. 83: 1492-9. PMID 25253748 DOI: 10.1212/Wnl.0000000000000905  0.033
2013 Shekelle PG, Wachter RM, Pronovost PJ, Schoelles K, McDonald KM, Dy SM, Shojania K, Reston J, Berger Z, Johnsen B, Larkin JW, Lucas S, Martinez K, Motala A, Newberry SJ, et al. Making health care safer II: an updated critical analysis of the evidence for patient safety practices. Evidence Report/Technology Assessment. 1-945. PMID 24423049  0.033
2007 Larkin JD, Bhat KL, Markham GD, Brooks BR, Lai JH, Bock CW. A computational investigation of the geometrical structure and protodeboronation of boroglycine, H2N-CH2-B(OH)2. The Journal of Physical Chemistry. A. 111: 6489-500. PMID 17595064 DOI: 10.1021/Jp0700682  0.033
2010 Fisher RA, Larkin J. Malignant melanoma (metastatic). Bmj Clinical Evidence. 2010. PMID 21418691  0.032
2008 Larkin J, Gore M. Malignant melanoma (metastatic). Bmj Clinical Evidence. 2008. PMID 19445806  0.032
2014 Sprouse C, Gordish-Dressman H, Orkunoglu-Suer EF, Lipof JS, Moeckel-Cole S, Patel RR, Adham K, Larkin JS, Hubal MJ, Kearns AK, Clarkson PM, Thompson PD, Angelopoulos TJ, Gordon PM, Moyna NM, et al. Response to Comment on Sprouse et al. SLC30A8 nonsynonymous variant is associated with recovery following exercise and skeletal muscle size and strength. Diabetes 2014;63:363-368. Diabetes. 63: e9-e10. PMID 24757210 DOI: 10.2337/Db14-0222  0.032
2009 Larkin J, Gore M. Health policy: The UK 'postcode lottery' in renal cell carcinoma. Nature Reviews. Urology. 6: 636-8. PMID 19956190 DOI: 10.1038/nrurol.2009.228  0.032
2010 Hubal MJ, Devaney JM, Hoffman EP, Zambraski EJ, Gordish-Dressman H, Kearns AK, Larkin JS, Adham K, Patel RR, Clarkson PM. CCL2 and CCR2 polymorphisms are associated with markers of exercise-induced skeletal muscle damage. Journal of Applied Physiology (Bethesda, Md. : 1985). 108: 1651-8. PMID 20339010 DOI: 10.1152/Japplphysiol.00361.2009  0.032
2014 Martin-Liberal J, Larkin J. New RAF kinase inhibitors in cancer therapy. Expert Opinion On Pharmacotherapy. 15: 1235-45. PMID 24766074 DOI: 10.1517/14656566.2014.911286  0.032
2014 Margolis R, Derr L, Dunn M, Huerta M, Larkin J, Sheehan J, Guyer M, Green ED. The National Institutes of Health's Big Data to Knowledge (BD2K) initiative: capitalizing on biomedical big data. Journal of the American Medical Informatics Association : Jamia. 21: 957-8. PMID 25008006 DOI: 10.1136/amiajnl-2014-002974  0.032
2011 Fisher R, Larkin J. Renal cell cancer: what can we learn from pre-operative studies? Frontiers in Oncology. 1: 51. PMID 22655250 DOI: 10.3389/fonc.2011.00051  0.031
2015 Lorigan P, Ascierto PA, Dummer R, Eggermont AM, Flaherty KT, Garbe C, Gogas H, Hauschild A, Kefford RF, Kirkwood JM, Larkin J, Long GV, Maio M, McArthur GA, Ribas A, et al. Expanded access programmes: patient interests versus clinical trial integrity. The Lancet. Oncology. 16: 15-7. PMID 25638540 DOI: 10.1016/S1470-2045(14)71161-1  0.031
2014 Connelly LS, Meckes B, Larkin J, Gillman AL, Wanunu M, Lal R. Graphene nanopore support system for simultaneous high-resolution AFM imaging and conductance measurements. Acs Applied Materials & Interfaces. 6: 5290-6. PMID 24581087 DOI: 10.1021/Am500639Q  0.031
2012 Robb WB, Falk GA, Larkin JO, Waldron R, Waldron RP. A 10-step intraoperative surgical checklist (ISC) for laparoscopic cholecystectomy-can it really reduce conversion rates to open cholecystectomy? Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 16: 1318-23. PMID 22528572 DOI: 10.1007/s11605-012-1886-6  0.031
2012 Larkin J, Bea L, Sharma A. A cost effective complement to managing the vitamin D deficient and anemic dialysis patient in the bundled world. Nephrology News & Issues. 26: 22-4, 26. PMID 22870564  0.03
2015 Waduge P, Larkin J, Upmanyu M, Kar S, Wanunu M. Programmed synthesis of freestanding graphene nanomembrane arrays. Small (Weinheim An Der Bergstrasse, Germany). 11: 597-603. PMID 25236988 DOI: 10.1002/Smll.201402230  0.03
2006 Larkin JM, Kaye SB. Epothilones in the treatment of cancer. Expert Opinion On Investigational Drugs. 15: 691-702. PMID 16732719 DOI: 10.1517/13543784.15.6.691  0.03
2013 O'Riordan JM, Larkin JO, Mehigan BJ, McCormick PH. Re-laparoscopy in the diagnosis and treatment of postoperative complications following laparoscopic colorectal surgery. The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 11: 183-6. PMID 23582883 DOI: 10.1016/j.surge.2013.01.002  0.029
2005 Larkin J, Rice C. Beyond "healthy eating" and "healthy weights": harassment and the health curriculum in middle schools. Body Image. 2: 219-32. PMID 18089190 DOI: 10.1016/j.bodyim.2005.07.001  0.029
2013 Harvie P, Larkin J, Scaddan M, Longstaff LM, Sloan K, Beaver RJ. Stiffness after total knee arthroplasty: does component alignment differ in knees requiring manipulation? A retrospective cohort study of 281 patients. The Journal of Arthroplasty. 28: 14-9. PMID 23217526 DOI: 10.1016/j.arth.2012.03.003  0.028
2011 Larkin JO, Walsh TJ, Wallis F, Waldron DJ. Pyometrium secondary to diverticular colouterine fistula. European Journal of Obstetrics, Gynecology, and Reproductive Biology. 156: 234-5. PMID 21450390 DOI: 10.1016/j.ejogrb.2011.01.017  0.028
2016 Wood EM, Barker Swarthout SE, Hochachka WM, Larkin JL, Rohrbaugh RW, Rosenberg KV, Rodewald AD. Intermediate habitat associations by hybrids may facilitate genetic introgression in a songbird Journal of Avian Biology. DOI: 10.1111/Jav.00771  0.027
2014 Stewart GD, Harrison DJ, Swanton C, Lewis R, Bliss J, Larkin J, Nicol DL. Multidisciplinary urological engagement in translational renal cancer research. Bju International. 114: 474-5. PMID 25146641 DOI: 10.1111/Bju.12697  0.027
2015 McCleary BV, McKie VA, Draga A, Rooney E, Mangan D, Larkin J. Hydrolysis of wheat flour arabinoxylan, acid-debranched wheat flour arabinoxylan and arabino-xylo-oligosaccharides by β-xylanase, α-L-arabinofuranosidase and β-xylosidase. Carbohydrate Research. 407: 79-96. PMID 25723624 DOI: 10.1016/j.carres.2015.01.017  0.026
2014 von Fricken ME, Weppelmann TA, Lam B, Eaton WT, Schick L, Masse R, Beau De Rochars MV, Existe A, Larkin J, Okech BA. Age-specific malaria seroprevalence rates: a cross-sectional analysis of malaria transmission in the Ouest and Sud-Est departments of Haiti. Malaria Journal. 13: 361. PMID 25218803 DOI: 10.1186/1475-2875-13-361  0.026
2007 Thornalley PJ, Babaei-Jadidi R, Al Ali H, Rabbani N, Antonysunil A, Larkin J, Ahmed A, Rayman G, Bodmer CW. High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease. Diabetologia. 50: 2164-70. PMID 17676306 DOI: 10.1007/s00125-007-0771-4  0.026
2013 Martin-Smith JD, Larkin JO, Ravi N, Reynolds JV. Severe epigastric pain following a birthday party. Irish Medical Journal. 106: 23. PMID 23472374  0.026
2015 Dickens AM, Larkin JR, Davis BG, Griffin JL, Claridge TDW, Sibson NR, Anthony DC. NMR-Based Metabolomics Separates the Distinct Stages of Disease in a Chronic Relapsing Model of Multiple Sclerosis Journal of Neuroimmune Pharmacology. DOI: 10.1007/s11481-015-9622-0  0.026
2005 Larkin JD, Bock CW, Schaefer Iii HF. Assessing alkyl-, silyl-, and halo-substituent effects on the electron affinities of silyl radicals. The Journal of Physical Chemistry. A. 109: 10100-5. PMID 16838930 DOI: 10.1021/jp052439p  0.026
2016 Larkin J. New Mercedes-Benz E-Class with test licence for autonomous driving: Self-driving across the highways of Nevada Automotive Industries Ai. 196.  0.026
2009 Martin-Smith JD, Larkin JO, O'Connell F, Ravi N, Reynolds JV. Management of gastro-bronchial fistula complicating a subtotal esophagectomy: a case report. Bmc Surgery. 9: 20. PMID 20030856 DOI: 10.1186/1471-2482-9-20  0.025
2008 Brangan P, Bailey DC, Larkin JF, Myers T, More SJ. Management of the national programme to eradicate equine infectious anaemia from Ireland during 2006: a review. Equine Veterinary Journal. 40: 702-4. PMID 19165941  0.025
2015 Gore M, Larkin J. Precision oncology: where next? The Lancet. Oncology. 16: 1593-5. PMID 26678189 DOI: 10.1016/S1470-2045(15)00473-8  0.025
2010 Giotakis N, Panchani SK, Narayan B, Larkin JJ, Al Maskari S, Nayagam S. Segmental fractures of the tibia treated by circular external fixation. The Journal of Bone and Joint Surgery. British Volume. 92: 687-92. PMID 20436007 DOI: 10.1302/0301-620X.92B5.22514  0.025
2015 Markel D, Larkin J, Leger P, Levesque IR, El Naqa I. Development of a multi-modality 4D biomechanical phantom for evaluation of simultaneous registration/segmentation algorithms Ifmbe Proceedings. 51: 373-376. DOI: 10.1007/978-3-319-19387-8_90  0.025
2007 Larkin J. MRCP(UK) part 2 clinical examination (PACES): examiners reflections. PACES: the training. Clinical Medicine (London, England). 7: 203-4. PMID 17491517  0.025
2015 Larkin J. Mercedesbenz USA launches mbrace connect For All MY2016 vehicles: Additional updates bring remote start, remote diagnostics, iHeartRadio App Automotive Industries Ai. 195.  0.024
2011 Philbin DM, Larkin JO, Ravi N, Wilson G, Reynolds JV. Recurrent melaena in a 21-year-old female. Anz Journal of Surgery. 81: 181-2. PMID 21342393 DOI: 10.1111/j.1445-2197.2010.05550.x  0.024
2014 Nobbenhuis MA, Lalondrelle S, Larkin J, Banerjee S. Management of melanomas of the gynaecological tract. Current Opinion in Oncology. 26: 508-13. PMID 25046205 DOI: 10.1097/CCO.0000000000000104  0.023
2015 Larkin JMG, Gore ME. The role of targeted therapy in special populations Renal Cell Carcinoma: Molecular Targets and Clinical Applications. 417-439. DOI: 10.1007/978-1-4939-1622-1_19  0.023
2007 Fearfield LA, Larkin JM, Rowe A, A'Hern R, Fisher C, Francis N, MacKie R, McCann B, Gore ME, Bunker CB. Expression of p16, CD95, CD95L and Helix pomatia agglutinin in relapsing and nonrelapsing very thin melanoma. The British Journal of Dermatology. 156: 440-7. PMID 17300231 DOI: 10.1111/j.1365-2133.2006.07581.x  0.023
2015 Larkin JD, Jenni NL, Floresco SB. Modulation of risk/reward decision making by dopaminergic transmission within the basolateral amygdala. Psychopharmacology. PMID 26432096 DOI: 10.1007/s00213-015-4094-8  0.023
2015 Larkin J. Voice box and Fujitsu ten deliver advanced head unit with natural language interface to subaru : Subaru incar experience stands out with Voice Box's contextual voice interface Automotive Industries Ai. 195.  0.022
2015 Larkin J. VoiceBox technologies and rivet radio partner to bring voice commands to personalized news platform: Companies form strategic alliance to demonstrate voice control for onthego curated news service Automotive Industries Ai. 195.  0.022
2013 Klooster A, Larkin JR, Wiersema-Buist J, Gans RO, Thornalley PJ, Navis G, van Goor H, Leuvenink HG, Bakker SJ. Are brain and heart tissue prone to the development of thiamine deficiency? Alcohol (Fayetteville, N.Y.). 47: 215-21. PMID 23357554 DOI: 10.1016/j.alcohol.2012.12.014  0.022
2008 Larkin JD, Bhat KL, Markham GD, James TD, Brooks BR, Bock CW. A computational characterization of boron-oxygen multiple bonding in HN=CH-CH=CH-NH-BO. The Journal of Physical Chemistry. A. 112: 8446-54. PMID 18707068 DOI: 10.1021/Jp800125P  0.022
2015 Waduge P, Bilgin I, Larkin J, Henley RY, Goodfellow K, Graham AC, Bell DC, Vamivakas N, Kar S, Wanunu M. Direct and Scalable Deposition of Atomically Thin Low-Noise MoS2 Membranes on Apertures. Acs Nano. 9: 7352-9. PMID 26111109 DOI: 10.1021/Acsnano.5B02369  0.022
2011 Larkin JM, Gore ME. Primary excision margins and sentinel lymph node biopsy in clinically node-negative melanoma of the trunk or extremities. Clinical Oncology (Royal College of Radiologists (Great Britain)). 23: 569-71. PMID 21658921 DOI: 10.1016/j.clon.2011.05.001  0.022
2015 Oliver V, Flicker S, Danforth J, Konsmo E, Wilson C, Jackson R, Restoule JP, Prentice T, Larkin J, Mitchell C. 'Women are supposed to be the leaders': intersections of gender, race and colonisation in HIV prevention with Indigenous young people. Culture, Health & Sexuality. 17: 906-19. PMID 25702802 DOI: 10.1080/13691058.2015.1009170  0.021
2014 Larkin JA. IAV to showcase highly automated driving technology at ITS World Congress in Detroit Automotive Industries Ai. 194.  0.021
2006 Ten Eyck G, Larkin J, David C, Puljan D, Jaramillo L, Selvage D. [P193]: The role of serotonin in frog development: Metamorphic and directly developing modes International Journal of Developmental Neuroscience. 24: 579-579. DOI: 10.1016/j.ijdevneu.2006.09.253  0.021
2014 Larkin JM, Turney JE, Massicotte AD, Amon CH, McGaughey AJH. Comparison and evaluation of spectral energy methods for predicting phonon properties Journal of Computational and Theoretical Nanoscience. 11: 249-256. DOI: 10.1166/Jctn.2014.3345  0.02
2011 Larkin J, Brooksby A, Lin CT, Zurbruegg R. Implied volatility smiles, option mispricing and net buying pressure: evidence around the global financial crisis Accounting & Finance. 52: 47-69. DOI: 10.1111/J.1467-629X.2011.00419.X  0.019
2011 Sibartie S, Larkin JO, Lee G, Fitzgibbon J, O'Reilly S, Richardson D. Metastatic uterine leiomyosarcoma presenting as a breast lump. Irish Journal of Medical Science. 180: 889-91. PMID 19184604 DOI: 10.1007/s11845-009-0286-8  0.019
2013 Larkin J, Henley R, Bell DC, Cohen-Karni T, Rosenstein JK, Wanunu M. Slow DNA transport through nanopores in hafnium oxide membranes. Acs Nano. 7: 10121-8. PMID 24083444 DOI: 10.1021/Nn404326F  0.019
2010 Flicker S, Guta A, Larkin J, Flynn S, Fridkin A, Travers R, Pole JD, Layne C. Survey design from the ground up: collaboratively creating the Toronto Teen Survey. Health Promotion Practice. 11: 112-22. PMID 18367639 DOI: 10.1177/1524839907309868  0.019
2008 More SJ, Aznar I, Bailey DC, Larkin JF, Leadon DP, Lenihan P, Flaherty B, Fogarty U, Brangan P. An outbreak of equine infectious anaemia in Ireland during 2006: investigation methodology, initial source of infection, diagnosis and clinical presentation, modes of transmission and spread in the Meath cluster. Equine Veterinary Journal. 40: 706-8. PMID 19165942 DOI: 10.2746/042516408X363305  0.019
2014 Chang DT, Thyer IA, Larkin JO, Wallace MH, Hayne D. First report of the stapled mesh stoma reinforcement technique in a urologic context. Case Reports in Urology. 2014: 294304. PMID 25405055 DOI: 10.1155/2014/294304  0.019
2016 Larkin J. Toyota research institute announces all-star leadership team for artificial intelligence: Almost thirty new projects launched through collaborative research partnership with MIT and Stanford Automotive Industries Ai. 196.  0.018
2015 Larkin J. Maxim brings expertise in high-performance analog integration to NVIDIA automotive platforms Automotive Industries Ai. 195.  0.018
2015 Walsh SM, Larkin JO. Sigmoid volvulus causing displacement of the liver and gastric outlet obstruction. Bmj Case Reports. 2015. PMID 26184359 DOI: 10.1136/bcr-2015-210317  0.018
2012 Larkin J. Should rheumatologists be managing fibromyalgia? Scottish Medical Journal. 57: 43-4. PMID 22408215 DOI: 10.1258/smj.2011.011186  0.018
2010 Chan PA, Connell NT, Gabonay AM, Westley B, Larkin JM, LaRosa SP, Chapin K, Mermel L. Oseltamivir-resistant 2009-2010 pandemic influenza A (H1N1) in an immunocompromised patient. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 16: 1576-8. PMID 20218988 DOI: 10.1111/j.1469-0691.2010.03212.x  0.017
2010 Larkin JG. Family history of rheumatoid arthritis--a non-predictor of inflammatory disease? Rheumatology (Oxford, England). 49: 608-9. PMID 19965975 DOI: 10.1093/rheumatology/kep386  0.016
2012 Larkin JM, Lorenz H, Rack L, Shatzer M. Good care, good science: leveraging frontline staff for quality. Nursing Administration Quarterly. 36: 188-93. PMID 22677958 DOI: 10.1097/NAQ.0b013e3182588b7d  0.016
2015 Larkin J. ANSYS Convergence Conferences feature thought leaders from Daimler, Airbus, BMW, John DeerE & VW Automotive Industries Ai. 195.  0.015
2015 Larkin J. IESF 2015 Automotive Integrated Electrical Solutions Forum returns to Detroit with new program Automotive Industries Ai. 195.  0.015
2016 Larkin J. Usabc issues RFPI to develop improved thermal management system for LI-ion batteries in vehicles Automotive Industries Ai. 196.  0.014
2008 Larkin J, Mitty J. Introduction: Lyme disease. Medicine and Health, Rhode Island. 91: 208-9. PMID 18705218  0.012
2008 Larkin JM. Ticks and tick-related illness. Medicine and Health, Rhode Island. 91: 209-11. PMID 18705219  0.012
2011 Law KP, Larkin JR. Recent advances in SALDI-MS techniques and their chemical and bioanalytical applications. Analytical and Bioanalytical Chemistry. 399: 2597-622. PMID 20730529 DOI: 10.1007/s00216-010-4063-3  0.012
2014 Larkin J, Foquet M, Turner SW, Korlach J, Wanunu M. Reversible positioning of single molecules inside zero-mode waveguides. Nano Letters. 14: 6023-9. PMID 25209321 DOI: 10.1021/Nl503134X  0.012
2014 Larkin J. Planes, trains and automobiles: Traveling by car uses most energy Automotive Industries Ai. 194.  0.011
2014 Larkin J. GAZ Group will present its autocomponent products at the Hannover Messe European Industrial Fair Automotive Industries Ai. 194.  0.011
2014 Roelfsema M, Elzen Md, Höhne N, Hof AF, Braun N, Fekete H, Böttcher H, Brandsma R, Larkin J. Are major economies on track to achieve their pledges for 2020? An assessment of domestic climate and energy policies Energy Policy. 67: 781-796. DOI: 10.1016/j.enpol.2013.11.055  0.011
2011 Larkin JO, Moriarity AR, O'Mahony D, Meaney J, Ravi N, Reynolds JV. Gallstone ileus in evolution. Anz Journal of Surgery. 81: 287-8. PMID 21418475 DOI: 10.1111/j.1445-2197.2011.05691.x  0.011
2014 Schadla-Hall T, Larkin J, Thornton A. Editorial Public Archaeology. 12: 219-220. DOI: 10.1179/1465518714Z.00000000049  0.01
2012 Davies S, Larkin J, Loosemore M, Montgomery H. Media reports fuelled by authors' claims. Bmj (Clinical Research Ed.). 345: e4495; author reply . PMID 22761102  0.01
2015 Cioe PA, Melbourne K, Larkin J. An immunization update for HIV-infected adults in the United States: review of the literature. The Journal of the Association of Nurses in Aids Care : Janac. 26: 201-7. PMID 25665888 DOI: 10.1016/j.jana.2014.11.006  0.01
2015 Waduge P, Bilgin I, Larkin J, Henley RY, Goodfellow K, Graham AC, Bell DC, Vamivakas N, Kar S, Wanunu M. Direct and Scalable Deposition of Atomically Thin Low-Noise MoS2 Membranes on Apertures Acs Nano. 9: 7352-7359. DOI: 10.1021/acsnano.5b02369  0.01
2015 Norman M, Larkin J, Vose A, Evans K. A case study of CUDA FORTRAN and OpenACC for an atmospheric climate kernel Journal of Computational Science. 9: 1-6. DOI: 10.1016/j.jocs.2015.04.022  0.01
2015 Larkin J. NXP semiconductors leverages ANSYS solutions to develop innovative car infotainment system Automotive Industries Ai. 195.  0.01
2015 Larkin J. BT assure ethical hacking for vehicles Automotive Industries Ai. 195.  0.01
2015 Larkin J. Automotive simulation world congress features global industry thought leaders : Presenters from leading customer companies include ferrari, ford, nissan, cummins, intel and amazon web services Automotive Industries Ai. 195.  0.01
2015 Larkin J. SMI and DEWESoft introduce driver machine monitoring and analysis platform for ADAS development Automotive Industries Ai. 195.  0.01
2015 Larkin J. Focus on safety when humans and machines interact Automotive Industries Ai. 195.  0.01
2014 Parrish KD, Jain A, Larkin JM, Saidi WA, McGaughey AJH. Origins of thermal conductivity changes in strained crystals Physical Review B - Condensed Matter and Materials Physics. 90. DOI: 10.1103/PhysRevB.90.235201  0.01
2014 Larkin JM, McGaughey AJH. Thermal conductivity accumulation in amorphous silica and amorphous silicon Physical Review B - Condensed Matter and Materials Physics. 89. DOI: 10.1103/PhysRevB.89.144303  0.01
2014 Larkin JA. Harris Williams & Co. advises Casco Automotive Group on its pending sale to Amphenol Corporation Automotive Industries Ai. 194.  0.01
2014 Larkin JA. Expanding the horizons for the next generation of designers Automotive Industries Ai. 194.  0.01
2012 Osilla KC, Van Busum K, Schnyer C, Larkin JW, Eibner C, Mattke S. Systematic review of the impact of worksite wellness programs. The American Journal of Managed Care. 18: e68-81. PMID 22435887  0.01
2011 Martin-Smith JD, Larkin JO, Hogan JG, Ravi N, Reynolds JV. Necrotizing pancreatitis presenting with pneumatosis coli and hepatic portal venous gas. Anz Journal of Surgery. 81: 467-8. PMID 22295352  0.01
2011 Mayer PL, Larkin JA, Hennessy JM. Amebic encephalitis. Surgical Neurology International. 2: 50. PMID 21697972 DOI: 10.4103/2152-7806.80115  0.01
2010 O'Callaghan A, Larkin J, Malone C, Kerin M. Description and validation of a novel programme for theatre-based surgical education. Medical Education. 44: 1129-30. PMID 20946494 DOI: 10.1111/j.1365-2923.2010.03811.x  0.01
2008 Larkin JM. Lyme disease in children and pregnant women. Medicine and Health, Rhode Island. 91: 212. PMID 18705220  0.01
2008 Carden CP, Myerson JS, Popat S, Montes A, Larkin JM, Benson MJ, O'Brien ME. Good vibrations and the power of positron thinking: positron emission tomography and endoscopic ultrasound in staging of mesothelioma-two case reports. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 3: 539-41. PMID 18449011 DOI: 10.1097/JTO.0b013e31816fca34  0.01
2007 Cullen IM, Larkin JO, Moore M, Fitzgeral E, O'Ríordáin M, Rogers E. Fournier's gangrene--findings on computed tomography. Thescientificworldjournal. 7: 1839-41. PMID 18040545 DOI: 10.1100/tsw.2007.250  0.01
2007 Larkin J, Flicker S, Koleszar-Green R, Mintz S, Dagnino M, Mitchell C. HIV risk, systemic inequities, and Aboriginal youth: widening the circle for HIV prevention programming. Canadian Journal of Public Health = Revue Canadienne De Santã© Publique. 98: 179-82. PMID 17626380  0.01
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