Helen J. Mitchell, Ph.D. - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
chemistry, biology, and medicine of natural and designed molecules

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Aggarwal VK, Armstrong SK, Caggiano L, Chibale K, Clayden J, Coldham I, Greeves N, Hartley RC, Knight JG, Kuhnert N, Mitchell HJ, Nelson A, O'Brien P, Thomas SP, Wyatt P. Stuart Warren (24 Dec 1938-22 Mar 2020). Organic & Biomolecular Chemistry. PMID 32936190 DOI: 10.1039/D0Ob90121K  0.334
2018 ElMarrouni A, Suen L, Wang C, Hunter D, Mitchell H, Converso A. Synthesis of HIV NNRTI Doravirine Analogues via Visible-Light Photoredox Decarboxylative Cross-Coupling Synthesis. 50: 3177-3186. DOI: 10.1055/S-0037-1610155  0.735
2010 Nicolaou KC, Mitchell HJ. ChemInform Abstract: Adventures in Carbohydrate Chemistry: New Synthetic Technologies, Chemical Synthesis, Molecular Design, and Chemical Biology Cheminform. 32: no-no. DOI: 10.1002/chin.200132256  0.431
2010 Nicolaou KC, Mitchell HJ, Fylaktakidou KC, Suzuki H, Rodriguez RM. ChemInform Abstract: 1,2-Seleno Migrations in Carbohydrate Chemistry: Solution and Solid-Phase Synthesis of 2-Deoxy Glycosides, Orthoesters, and Allyl Orthoesters. Cheminform. 31: no-no. DOI: 10.1002/chin.200022188  0.444
2010 Nicolaou KC, Mitchell HJ, Rodriguez RM, Fylaktakidou KC, Suzuki H. ChemInform Abstract: Total Synthesis of Everninomicin 13,384-1. Part 3. Synthesis of the DE Fragment and Completion of the Total Synthesis. Cheminform. 31: no-no. DOI: 10.1002/chin.200011239  0.538
2010 Nicolaou KC, Mitchell HJ, Suzuki H, Rodriguez RM, Baudoin O, Fylaktakidou KC. ChemInform Abstract: Total Synthesis of Everninomicin 13,384-1. Part 1. Synthesis of the A1B(A)C Fragment. Cheminform. 31: no-no. DOI: 10.1002/chin.200011237  0.7
2010 Nicolaou KC, Mitchell HJ, Jain NF, Winssinger N, Hughes R, Bando T. ChemInform Abstract: Total Synthesis of Vancomycin. Cheminform. 30: no-no. DOI: 10.1002/chin.199918228  0.659
2010 NICOLAOU KC, RODRIGUEZ RM, MITCHELL HJ, VAN DELFT FL. ChemInform Abstract: Stereocontrolled Synthesis of the Everninomicin A1B(A)C Ring Framework. Cheminform. 29: no-no. DOI: 10.1002/chin.199849288  0.493
2010 NICOLAOU KC, MITCHELL HJ, VAN DELFT FL, RUEBSAM F, RODRIGUEZ RM. ChemInform Abstract: Expeditious Routes to Evernitrose and Vancosamine Derivatives and Synthesis of a Model Vancomycin Aryl Glycoside. Cheminform. 29: no-no. DOI: 10.1002/chin.199849287  0.473
2010 NICOLAOU KC, VAN DELFT FL, CONLEY SR, MITCHELL HJ, JIN Z, RODRIGUEZ RM. ChemInform Abstract: New Synthetic Technology for the Stereocontrolled Construction of 1,1′-Disaccharides and 1,1′:1′′,2-Trisaccharides. Synthesis of the FG Ring System of Everninomicin 13,384-1. Cheminform. 29: no-no. DOI: 10.1002/chin.199801233  0.461
2004 Nicolaou KC, Mitchell HJ, Snyder SA. Synthesis of Complex Carbohydrates: Everninomicin 13,384-1 Cheminform. 35. DOI: 10.1002/chin.200430258  0.495
2003 Nicolaou KC, Li Y, Sugita K, Monenschein H, Guntupalli P, Mitchell HJ, Fylaktakidou KC, Vourloumis D, Giannakakou P, O'Brate A. Total synthesis of apoptolidin: completion of the synthesis and analogue synthesis and evaluation. Journal of the American Chemical Society. 125: 15443-54. PMID 14664590 DOI: 10.1021/Ja030496V  0.673
2003 Nicolaou KC, Fylaktakidou KC, Monenschein H, Li Y, Weyershausen B, Mitchell HJ, Wei HX, Guntupalli P, Hepworth D, Sugita K. Total synthesis of apoptolidin: construction of enantiomerically pure fragments. Journal of the American Chemical Society. 125: 15433-42. PMID 14664589 DOI: 10.1021/Ja0304953  0.68
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Sugita K. Total Synthesis of Apoptolidin: Part 2. Coupling of Key Building Blocks and Completion of the Synthesis. Angewandte Chemie (International Ed. in English). 40: 3854-3857. PMID 29712136 DOI: 10.1002/1521-3773(20011015)40:20<3854::Aid-Anie3854>3.0.Co;2-D  0.668
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Wei HX, Weyershausen B. Total Synthesis of Apoptolidin: Part 1. Retrosynthetic Analysis and Construction of Building Blocks. Angewandte Chemie (International Ed. in English). 40: 3849-3854. PMID 29712121 DOI: 10.1002/1521-3773(20011015)40:20<3849::Aid-Anie3849>3.0.Co;2-M  0.646
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Sugita K. Total Synthesis of Apoptolidin: Part 2. Coupling of Key Building Blocks and Completion of the Synthesis We thank Dr. C. Khosla and Dr. Y. Hayakawa for generous gifts of apoptolidin, and Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), the Skaggs Institute for Chemical Biology, American Biosciences, a predoctoral fellowship from Boehringer Ingelheim (to Y.L.), a postdoctoral fellowship the George Hewitt Foundation (to K.C.F.), and grants from Abbott Laboratories, ArrayBiopharma, Bayer, Boehringer Ingelheim, DuPont, Glaxo, Hoffmann-LaRoche, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 3854-3857. PMID 11668554 DOI: 10.1002/1521-3773(20011015)40:20<3854::AID-ANIE3854>3.0.CO;2-D  0.579
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Wei HX, Weyershausen B. Total Synthesis of Apoptolidin: Part 1. Retrosynthetic Analysis and Construction of Building Blocks We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), the Skaggs Institute for Chemical Biology, American Biosciences, a pre-doctoral fellowship from Boehringer Ingelheim (Y.L.), a postdoctoral fellowship the George Hewitt Foundation (K.C.F.), and grants from Abbott Laboratories, ArrayBiopharma, Bayer, Boehringer Ingelheim, DuPont, Glaxo, Hoffmann-LaRoche, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 3849-3854. PMID 11668553 DOI: 10.1002/1521-3773(20011015)40:20<3849::AID-ANIE3849>3.0.CO;2-M  0.539
2001 Nicolaou KC, Mitchell HJ. Adventures in Carbohydrate Chemistry: New Synthetic Technologies, Chemical Synthesis, Molecular Design, and Chemical Biology A list of abbreviations can be found at the end of this article. Telemachos Charalambous was an inspiring teacher at the Pancyprian Gymnasium, Nicosia, Cyprus. Angewandte Chemie (International Ed. in English). 40: 1576-1624. PMID 11353467 DOI: 10.1002/1521-3773(20010504)40:9<1576::Aid-Anie15760>3.0.Co;2-G  0.541
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Sugita K. Totalsynthese von Apoptolidin - Teil 2: Verknüpfung der Schlüsselintermediate und Abschluss der Synthese Angewandte Chemie. 113: 3972-3976. DOI: 10.1002/1521-3757(20011015)113:20<3972::Aid-Ange3972>3.0.Co;2-Z  0.596
2001 Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Wei H, Weyershausen B. Totalsynthese von Apoptolidin - Teil 1: Retrosynthese und Aufbau von Schlüsselintermediaten Angewandte Chemie. 113: 3968-3972. DOI: 10.1002/1521-3757(20011015)113:20<3968::Aid-Ange3968>3.0.Co;2-1  0.518
2001 Nicolaou KC, Mitchell HJ. Abenteuer in der Kohlenhydratchemie: Synthesestrategien, Synthesemethoden, Moleküldesign und biologische Chemie Angewandte Chemie. 113: 1624-1672. DOI: 10.1002/1521-3757(20010504)113:9<1624::Aid-Ange16240>3.0.Co;2-N  0.417
2000 Nicolaou KC, Fylaktakidou KC, Mitchell HJ, van Delft FL, Rodríguez RM, Conley SR, Jin Z. Total synthesis of everninomicin 13,384-1--Part 4: explorations of methodology; stereocontrolled synthesis of 1,1'-disaccharides, 1,2-seleno migrations in carbohydrates, and solution- and solid-phase synthesis of 2-deoxy glycosides and orthoesters. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 3166-85. PMID 11002995 DOI: 10.1002/1521-3765(20000901)6:17<3166::Aid-Chem3166>3.0.Co;2-Z  0.594
2000 Nicolaou KC, Mitchell HJ, Rodríguez RM, Fylaktakidou KC, Suzuki H, Conley SR. Total synthesis of everninomicin 13,384-1--Part 3: synthesis of the DE fragment and completion of the total synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 3149-65. PMID 11002994 DOI: 10.1002/1521-3765(20000901)6:17<3149::Aid-Chem3149>3.0.Co;2-L  0.596
2000 Nicolaou KC, Mitchell HJ, Fylaktakidou KC, Rodríguez RM, Suzuki H. Total synthesis of everninomicin 13,384-1--Part 2: synthesis of the FGHA2 fragment. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 3116-48. PMID 11002993 DOI: 10.1002/1521-3765(20000901)6:17<3116::Aid-Chem3116>3.0.Co;2-8  0.592
2000 Nicolaou KC, Rodríguez RM, Mitchell HJ, Suzuki H, Fylaktakidou KC, Baudoin O, van Delft FL. Total synthesis of everninomicin 13,384-1--Part 1: retrosynthetic analysis and synthesis of the A1B(A)C fragment. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 3095-115. PMID 11002992 DOI: 10.1002/1521-3765(20000901)6:17<3095::Aid-Chem3095>3.0.Co;2-4  0.703
2000 Nicolaou KC, Mitchell HJ, Fylaktakidou KC, Suzuki H, Rodríguez RM. 1,2-Seleno Migrations in Carbohydrate Chemistry: Solution and Solid-Phase Synthesis of 2-Deoxy Glycosides, Orthoesters, and Allyl Orthoesters We thank Drs. D. H. Huang and G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. We gratefully thank Nicolas Winssinger for helpful discussions and preparation of the selenium bromide resin. This work was financially supported by the Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), postdoctoral fellowships from M.E.C., Spain (R.M.R., Fullbright), the Japan Society for the Promotion of Science (H.S.), the George Hewitt Foundation (K.C.F.), and grants from Schering Plough, Pfizer, Glaxo, Merck, Hoffmann - La Roche, DuPont, Abbott Laboratories, and Boehringer - Ingelheim. Angewandte Chemie (International Ed. in English). 39: 1089-1093. PMID 10760930 DOI: 10.1002/(Sici)1521-3773(20000317)39:6<1089::Aid-Anie1089>3.0.Co;2-V  0.463
2000 Nicolaou KC, Pfefferkorn JA, Barluenga S, Mitchell HJ, Roecker AJ, Cao GQ. Natural product-like combinatorial libraries based on privileged structures. 3. The 'libraries from libraries' principle for diversity enhancement of benzopyran libraries Journal of the American Chemical Society. 122: 9968-9976. DOI: 10.1021/Ja0020355  0.742
2000 Nicolaou KC, Pfefferkorn JA, Mitchell HJ, Roecker AJ, Barluenga S, Cao GQ, Affleck RL, Lillig JE. Natural product-like combinatorial libraries based on privileged structures. 2. Construction of a 10 000-membered benzopyran library by directed split-and-pool chemistry using NanoKans and optical encoding Journal of the American Chemical Society. 122: 9954-9967. DOI: 10.1021/Ja002034C  0.758
2000 Nicolaou KC, Pfefferkorn JA, Roecker AJ, Cao GQ, Barluenga S, Mitchell HJ. Natural product-like combinatorial libraries based on privileged structures. 1. General principles and solid-phase synthesis of benzopyrans Journal of the American Chemical Society. 122: 9939-9953. DOI: 10.1021/Ja002033K  0.768
1999 Nicolaou KC, Mitchell HJ, Rodríguez RM, Fylaktakidou KC, Suzuki H. Total Synthesis of Everninomicin 13,384-1-Part 3: Synthesis of the DE Fragment and Completion of the Total Synthesis. Angewandte Chemie (International Ed. in English). 38: 3345-3350. PMID 10602190 DOI: 10.1002/(Sici)1521-3773(19991115)38:22<3345::Aid-Anie3345>3.0.Co;2-9  0.592
1999 Nicolaou KC, Rodríguez RM, Fylaktakidou KC, Suzuki H, Mitchell HJ. Total Synthesis of Everninomicin 13,384-1-Part 2: Synthesis of the FGHA(2) Fragment. Angewandte Chemie (International Ed. in English). 38: 3340-3345. PMID 10602189 DOI: 10.1002/(Sici)1521-3773(19991115)38:22<3340::Aid-Anie3340>3.0.Co;2-2  0.596
1999 Nicolaou KC, Mitchell HJ, Suzuki H, Rodríguez RM, Baudoin O, Fylaktakidou KC. Total Synthesis of Everninomicin 13,384-1-Part 1: Synthesis of the A(1)B(A)C Fragment. Angewandte Chemie (International Ed. in English). 38: 3334-3339. PMID 10602188 DOI: 10.1002/(SICI)1521-3773(19991115)38:22<3334::AID-ANIE3334>3.0.CO;2-H  0.551
1999 Nicolaou KC, Mitchell HJ, Jain NF, Winssinger N, Hughes R, Bando T. Total Synthesis of Vancomycin Angewandte Chemie International Edition. 38: 240-244. DOI: 10.1002/(Sici)1521-3773(19990115)38:1/2<240::Aid-Anie240>3.0.Co;2-5  0.741
1999 Nicolaou KC, Mitchell HJ, Jain NF, Bando T, Hughes R, Winssinger N, Natarajan S, Koumbis AE. Total Synthesis of Vancomycin—Part 4: Attachment of the Sugar Moieties and Completion of the Synthesis Chemistry - a European Journal. 5: 2648-2667. DOI: 10.1002/(Sici)1521-3765(19990903)5:9<2648::Aid-Chem2648>3.0.Co;2-Q  0.748
1999 Nicolaou K, Mitchell H, Rodríguez R, Fylaktakidou K, Suzuki H. Totalsynthese von Everninomicin 13,384-1 – Teil 3: Synthese des DE-Fragments und Abschluß der Totalsynthese Angewandte Chemie. 111: 3535-3540. DOI: 10.1002/(Sici)1521-3757(19991115)111:22<3535::Aid-Ange3535>3.0.Co;2-S  0.465
1999 Nicolaou K, Rodríguez R, Fylaktakidou K, Suzuki H, Mitchell H. Totalsynthese von Everninomicin 13,384-1 – Teil 2: Synthese des FGHA2-Fragments Angewandte Chemie. 111: 3529-3534. DOI: 10.1002/(Sici)1521-3757(19991115)111:22<3529::Aid-Ange3529>3.0.Co;2-6  0.428
1999 Nicolaou KC, Mitchell HJ, Jain NF, Winssinger N, Hughes R, Bando T. Totalsynthese von Vancomycin Angewandte Chemie. 111: 253-255. DOI: 10.1002/(Sici)1521-3757(19990115)111:1/2<253::Aid-Ange253>3.0.Co;2-V  0.675
1999 Nicolaou KC, Mitchell HJ, Jain NF, Bando T, Hughes R, Winssinger N, Natarajan S, Koumbis AE. Total synthesis of vancomycin - Part 4: Attachment of the sugar moieties and completion of the synthesis Chemistry - a European Journal. 5: 2648-2667.  0.636
1998 Nicolaou KC, Rodríguez RM, Mitchell HJ, Delft FLv. Stereocontrolled Synthesis Of The Everninomicin A1B(A)C Ring Framework Angewandte Chemie. 37: 1874-1876. DOI: 10.1002/(Sici)1521-3773(19980803)37:13/14<1874::Aid-Anie1874>3.0.Co;2-K  0.529
1998 Nicolaou KC, Mitchell HJ, Delft FLv, Rübsam F, Rodríguez RM. Expeditious Routes to Evernitrose and Vancosamine Derivatives and Synthesis of a Model Vancomycin Aryl Glycoside Angewandte Chemie. 37: 1871-1874. DOI: 10.1002/(Sici)1521-3773(19980803)37:13/14<1871::Aid-Anie1871>3.0.Co;2-1  0.513
1998 Nicolaou KC, Rodríguez RM, Mitchell HJ, Delft FLv. Stereoselektive Synthese des Everninomicin‐A1B(A)C‐Gerüsts Angewandte Chemie. 110: 1975-1977. DOI: 10.1002/(Sici)1521-3757(19980703)110:13/14<1975::Aid-Ange1975>3.0.Co;2-K  0.486
1998 Nicolaou KC, Mitchell HJ, van Delft FL, Rübsam F, Rodríguez RM. Einfache Zugänge zu Evernitrose und Vancosaminderivaten sowie Synthese eines Vancomycin-Modellglycosids Angewandte Chemie. 110: 1972-1974. DOI: 10.1002/(Sici)1521-3757(19980703)110:13/14<1972::Aid-Ange1972>3.0.Co;2-1  0.441
1998 Nicolaou KC, Rodríguez RM, Mitchell HJ, Van Delft FL. Stereocontrolled synthesis of the everninomicin A1B(A)C ring framework Angewandte Chemie - International Edition. 37: 1874-1876.  0.347
1998 Nicolaou KC, Mitchell HJ, Van Delft FL, Rübsam F, Rodríguez RM. Expeditious routes to evernitrose and vancosamine derivatives and synthesis of a model vancomycin aryl glycoside Angewandte Chemie - International Edition. 37: 1871-1874.  0.324
1997 Nicolaou KC, Van Delft FL, Conley SR, Mitchell HJ, Jin Z, Rodgriguez RM. New synthetic technology for the stereocontrolled construction of 1,1'-disaccharides and 1,1':1'',2-Trisaccharides. Synthesis of the FG ring system of everninomicin 13,384-1 Journal of the American Chemical Society. 119: 9057-9058. DOI: 10.1021/Ja971574F  0.517
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