Year |
Citation |
Score |
2013 |
Nevola L, Rodriguez JM, Thompson S, Hamilton AD. Super-secondary structure peptidomimetics: design and synthesis of an α-α hairpin analogue. Supramolecular Chemistry. 25: 586-590. PMID 26052191 DOI: 10.1080/10610278.2013.817581 |
0.563 |
|
2013 |
Martucci WE, Rodriguez JM, Vargo MA, Marr M, Hamilton AD, Anderson KS. Exploring novel strategies for AIDS protozoal pathogens: α-helix mimetics targeting a key allosteric protein-protein interaction in C. hominis TS-DHFR. Medchemcomm. 4. PMID 24324854 DOI: 10.1039/C3Md00141E |
0.504 |
|
2011 |
Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner. The Journal of Biological Chemistry. 286: 9382-92. PMID 21148306 DOI: 10.1074/Jbc.M110.203638 |
0.647 |
|
2009 |
Rodriguez JM, Ross NT, Katt WP, Dhar D, Lee GI, Hamilton AD. Structure and function of benzoylurea-derived alpha-helix mimetics targeting the Bcl-x(L)/Bak binding interface. Chemmedchem. 4: 649-56. PMID 19330783 DOI: 10.1002/Cmdc.200800387 |
0.663 |
|
2009 |
Rodriguez JM, Nevola L, Ross NT, Lee GI, Hamilton AD. Synthetic inhibitors of extended helix-protein interactions based on a biphenyl 4,4'-dicarboxamide scaffold. Chembiochem : a European Journal of Chemical Biology. 10: 829-33. PMID 19263447 DOI: 10.1002/Cbic.200800715 |
0.518 |
|
2007 |
Rodriguez JM, Hamilton AD. Benzoylurea oligomers: synthetic foldamers that mimic extended alpha helices. Angewandte Chemie (International Ed. in English). 46: 8614-7. PMID 17918270 DOI: 10.1002/Anie.200701869 |
0.438 |
|
2007 |
Becerril J, Rodriguez JM, Saraogi I, Hamilton AD. Foldamer-based Molecular Recognition Foldamers: Structure, Properties, and Applications. 193-228. DOI: 10.1002/9783527611478.ch7 |
0.588 |
|
2006 |
Rodriguez JM, Hamilton AD. Intramolecular hydrogen bonding allows simple enaminones to structurally mimic the i, i+4, and i+7 residues of an α-helix Tetrahedron Letters. 47: 7443-7446. DOI: 10.1016/J.Tetlet.2006.08.048 |
0.442 |
|
2005 |
Yin H, Lee GI, Sedey KA, Rodriguez JM, Wang HG, Sebti SM, Hamilton AD. Terephthalamide derivatives as mimetics of helical peptides: disruption of the Bcl-x(L)/Bak interaction. Journal of the American Chemical Society. 127: 5463-8. PMID 15826183 DOI: 10.1021/Ja0446404 |
0.63 |
|
2005 |
Yin H, Lee GI, Park HS, Payne GA, Rodriguez JM, Sebti SM, Hamilton AD. Terphenyl-based helical mimetics that disrupt the p53/HDM2 interaction. Angewandte Chemie (International Ed. in English). 44: 2704-7. PMID 15765497 DOI: 10.1002/Anie.200462316 |
0.564 |
|
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