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Erin E. West, Ph.D. - Publications

Affiliations: 
2011 Biological and Biomedical Sciences Emory University, Atlanta, GA 
Area:
Immunology, Microbiology
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46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Spolski R, Li P, Chandra V, Shin B, Goel S, Sakamoto K, Liu C, Oh J, Ren M, Enomoto Y, West EE, Christensen SM, Wan ECK, Ge M, Lin JX, et al. Distinct use of super-enhancer elements controls cell type-specific CD25 transcription and function. Science Immunology. 8: eadi8217. PMID 37922339 DOI: 10.1126/sciimmunol.adi8217  0.465
2023 West EE, Merle NS, Kamiński MM, Palacios G, Kumar D, Wang L, Bibby JA, Overdahl K, Jarmusch AK, Freeley S, Lee DY, Thompson JW, Yu ZX, Taylor N, Sitbon M, et al. Loss of CD4 T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection. Immunity. PMID 37572656 DOI: 10.1016/j.immuni.2023.07.014  0.51
2022 Bibby JA, Agarwal D, Freiwald T, Kunz N, Merle NS, West EE, Singh P, Larochelle A, Chinian F, Mukherjee S, Afzali B, Kemper C, Zhang NR. Systematic single-cell pathway analysis to characterize early T cell activation. Cell Reports. 41: 111697. PMID 36417885 DOI: 10.1016/j.celrep.2022.111697  0.343
2022 Hashimoto M, Araki K, Cardenas MA, Li P, Jadhav RR, Kissick HT, Hudson WH, McGuire DJ, Obeng RC, Wieland A, Lee J, McManus DT, Ross JL, Im SJ, Lee J, ... ... West EE, et al. PD-1 combination therapy with IL-2 modifies CD8 T cell exhaustion program. Nature. PMID 36171288 DOI: 10.1038/s41586-022-05257-0  0.677
2021 Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, et al. Autocrine vitamin D signaling switches off pro-inflammatory programs of T1 cells. Nature Immunology. PMID 34764490 DOI: 10.1038/s41590-021-01080-3  0.456
2021 Ebina-Shibuya R, West EE, Spolski R, Li P, Oh J, Kazemian M, Gromer D, Swanson P, Du N, McGavern DB, Leonard WJ. Thymic stromal lymphopoietin limits primary and recall CD8 T-cell anti-viral responses. Elife. 10. PMID 33439121 DOI: 10.7554/eLife.61912  0.504
2020 McGregor R, Chauss D, Freiwald T, Yan B, Wang L, Nova-Lamperti E, Zhang Z, Teague H, West EE, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz D, Portilla D, et al. An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19. Biorxiv : the Preprint Server For Biology. PMID 32743590 DOI: 10.1101/2020.07.18.210161  0.49
2020 Kolev M, West EE, Kunz N, Chauss D, Moseman EA, Rahman J, Freiwald T, Balmer ML, Lötscher J, Dimeloe S, Rosser EC, Wedderburn LR, Mayer-Barber KD, Bohrer A, Lavender P, et al. Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells. Immunity. 52: 513-527.e8. PMID 32187519 DOI: 10.1016/J.Immuni.2020.02.006  0.402
2020 West EE, Kunz N, Kemper C. Complement and human T cell metabolism: Location, location, location. Immunological Reviews. PMID 32166778 DOI: 10.1111/Imr.12852  0.419
2019 Spolski R, West EE, Li P, Veenbergen S, Yang S, Kazemian M, Oh J, Yu ZX, Freeman A, Holland S, Murphy PM, Leonard WJ. IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to . Elife. 8. PMID 30969166 DOI: 10.7554/Elife.45501  0.355
2019 Spolski R, West EE, Li P, Veenbergen S, Yung S, Kazemian M, Oh J, Yu Z, Freeman AF, Holland SM, Murphy PM, Leonard WJ. Author response: IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus Elife. DOI: 10.7554/Elife.45501.026  0.345
2018 Freeley S, Cardone J, Günther SC, West EE, Reinheckel T, Watts C, Kemper C, Kolev MV. Asparaginyl Endopeptidase (Legumain) Supports Human Th1 Induction via Cathepsin L-Mediated Intracellular C3 Activation. Frontiers in Immunology. 9: 2449. PMID 30405635 DOI: 10.3389/Fimmu.2018.02449  0.527
2018 Arbore G, West EE, Rahman J, Le Friec G, Niyonzima N, Pirooznia M, Tunc I, Pavlidis P, Powell N, Li Y, Liu P, Servais A, Couzi L, Fremeaux-Bacchi V, Placais L, et al. Complement receptor CD46 co-stimulates optimal human CD8 T cell effector function via fatty acid metabolism. Nature Communications. 9: 4186. PMID 30305631 DOI: 10.1038/S41467-018-06706-Z  0.492
2018 West EE, Afzali B, Kemper C. Unexpected Roles for Intracellular Complement in the Regulation of Th1 Responses. Advances in Immunology. 138: 35-70. PMID 29731006 DOI: 10.1016/Bs.Ai.2018.02.001  0.378
2018 West EE, Kolev M, Kemper C. Complement and the Regulation of T Cell Responses. Annual Review of Immunology. 36: 309-338. PMID 29677470 DOI: 10.1146/Annurev-Immunol-042617-053245  0.459
2018 West EE, Freeley S, Veenbergen S, Lee D, St. John-Williams L, Thompson JW, Scholl-Buergi S, Karall D, Huemer M, Kemper C. You are what you eat: CD46 regulated amino acid usage dictates T cell function Molecular Immunology. 102: 228. DOI: 10.1016/J.Molimm.2018.06.245  0.476
2018 Arbore G, Le Friec G, West EE, Niyonzima N, Rahman J, Pavlidis P, Powell N, Afzali B, Lavender P, Lachmann HJ, Kemper C. Complement receptor CD46 is a key co-stimulator for optimal human CD8+ T cell effector function Molecular Immunology. 102: 172. DOI: 10.1016/J.Molimm.2018.06.118  0.481
2017 Youngblood B, Hale JS, Kissick HT, Ahn E, Xu X, Wieland A, Araki K, West EE, Ghoneim HE, Fan Y, Dogra P, Davis CW, Konieczny BT, Antia R, Cheng X, et al. Effector CD8 T cells dedifferentiate into long-lived memory cells. Nature. PMID 29236683 DOI: 10.1038/Nature25144  0.608
2017 Li P, Mitra S, Spolski R, Oh J, Liao W, Tang Z, Mo F, Li X, West EE, Gromer D, Lin JX, Liu C, Ruan Y, Leonard WJ. STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078395 DOI: 10.1073/Pnas.1714019114  0.358
2016 West EE, Spolski R, Kazemian M, Yu ZX, Kemper C, Leonard WJ. A TSLP-complement axis mediates neutrophil killing of methicillin-resistant Staphylococcus aureus. Science Immunology. 1. PMID 28783679 DOI: 10.1126/Sciimmunol.Aaf8471  0.327
2016 Arbore G, West EE, Spolski R, Robertson AA, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, et al. T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells. Science (New York, N.Y.). 352: aad1210. PMID 27313051 DOI: 10.1126/Science.Aad1210  0.512
2014 Du N, Kwon H, Li P, West EE, Oh J, Liao W, Yu Z, Ren M, Leonard WJ. EGR2 is critical for peripheral naïve T-cell differentiation and the T-cell response to influenza. Proceedings of the National Academy of Sciences of the United States of America. 111: 16484-9. PMID 25368162 DOI: 10.1073/Pnas.1417215111  0.56
2014 Penaloza-MacMaster P, Kamphorst AO, Wieland A, Araki K, Iyer SS, West EE, O'Mara L, Yang S, Konieczny BT, Sharpe AH, Freeman GJ, Rudensky AY, Ahmed R. Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection. The Journal of Experimental Medicine. 211: 1905-18. PMID 25113973 DOI: 10.1084/Jem.20132577  0.65
2014 Proctor WR, Chakraborty M, Fullerton AM, Korrapati MC, Ryan PM, Semple K, Morrison JC, Berkson JD, Chea LS, Yang Q, Li AP, Spolski R, West EE, Rochman Y, Leonard WJ, et al. Thymic stromal lymphopoietin and interleukin-4 mediate the pathogenesis of halothane-induced liver injury in mice. Hepatology (Baltimore, Md.). 60: 1741-52. PMID 24723460 DOI: 10.1002/Hep.27169  0.311
2014 Liao W, Spolski R, Li P, Du N, West EE, Ren M, Mitra S, Leonard WJ. Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression. Proceedings of the National Academy of Sciences of the United States of America. 111: 3508-13. PMID 24550509 DOI: 10.1073/Pnas.1301138111  0.363
2013 West EE, Jin HT, Rasheed AU, Penaloza-Macmaster P, Ha SJ, Tan WG, Youngblood B, Freeman GJ, Smith KA, Ahmed R. PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells. The Journal of Clinical Investigation. 123: 2604-15. PMID 23676462 DOI: 10.1172/Jci67008  0.631
2013 Wan CK, Oh J, Li P, West EE, Wong EA, Andraski AB, Spolski R, Yu ZX, He J, Kelsall BL, Leonard WJ. The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells. Immunity. 38: 514-27. PMID 23453633 DOI: 10.1016/J.Immuni.2013.02.011  0.471
2013 Tan WG, Jin HT, West EE, Penaloza-MacMaster P, Wieland A, Zilliox MJ, McElrath MJ, Barouch DH, Ahmed R. Comparative analysis of simian immunodeficiency virus gag-specific effector and memory CD8+ T cells induced by different adenovirus vectors. Journal of Virology. 87: 1359-72. PMID 23175355 DOI: 10.1128/Jvi.02055-12  0.566
2013 Wan EC, Oh J, Li P, West EE, Wong EA, Andraski AB, Spolski R, Yu Z, He J, Kelsall BL, Leonard WJ. 270 : The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells Cytokine. 63: 307. DOI: 10.1016/J.Cyto.2013.06.273  0.433
2012 West EE, Kashyap M, Leonard WJ. TSLP: A Key Regulator of Asthma Pathogenesis. Drug Discovery Today. Disease Mechanisms. 9. PMID 24348685 DOI: 10.1016/J.Ddmec.2012.09.003  0.333
2011 Youngblood B, Oestreich KJ, Ha SJ, Duraiswamy J, Akondy RS, West EE, Wei Z, Lu P, Austin JW, Riley JL, Boss JM, Ahmed R. Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity. 35: 400-12. PMID 21943489 DOI: 10.1016/J.Immuni.2011.06.015  0.635
2011 West EE, Youngblood B, Tan WG, Jin HT, Araki K, Alexe G, Konieczny BT, Calpe S, Freeman GJ, Terhorst C, Haining WN, Ahmed R. Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load. Immunity. 35: 285-98. PMID 21856186 DOI: 10.1016/J.Immuni.2011.05.017  0.611
2010 Jin HT, Anderson AC, Tan WG, West EE, Ha SJ, Araki K, Freeman GJ, Kuchroo VK, Ahmed R. Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America. 107: 14733-8. PMID 20679213 DOI: 10.1073/Pnas.1009731107  0.677
2010 Mueller SN, Vanguri VK, Ha SJ, West EE, Keir ME, Glickman JN, Sharpe AH, Ahmed R. PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice. The Journal of Clinical Investigation. 120: 2508-15. PMID 20551512 DOI: 10.1172/Jci40040  0.584
2010 Shah PD, West EE, Whitlock AB, Orens JB, McDyer JF. CD154 deficiency uncouples allograft CD8+ T-cell effector function from proliferation and inhibits murine airway obliteration. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9: 2697-706. PMID 20021479 DOI: 10.1111/j.1600-6143.2009.02805.x  0.425
2009 D'Alessio FR, Tsushima K, Aggarwal NR, West EE, Willett MH, Britos MF, Pipeling MR, Brower RG, Tuder RM, McDyer JF, King LS. CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury. The Journal of Clinical Investigation. 119: 2898-913. PMID 19770521 DOI: 10.1172/Jci36498  0.398
2009 Shah P, Whitlock A, West E, Orens J, McDyer J. 564: Lack of CD154 Costimulation Induces Airway Allograft Tolerance Via Uncoupling of Allospecific CD8+ T Cell Proliferation from Effector Function in an IL-12 Independent Manner The Journal of Heart and Lung Transplantation. 28: S262. DOI: 10.1016/J.Healun.2008.11.571  0.537
2009 Pipeling M, West E, Whitlock A, Forman M, Valsamakis A, Lechtzin N, Orens J, McDyer J. 541: Increased CMV-Specific CD8+ Effectors and Viral Loads in the Lung Allograft Predict Viral Pneumonitis during Primary Infection The Journal of Heart and Lung Transplantation. 28: S254. DOI: 10.1016/J.Healun.2008.11.548  0.381
2008 Chen ES, Wahlström J, Song Z, Willett MH, Wikén M, Yung RC, West EE, McDyer JF, Zhang Y, Eklund A, Grunewald J, Moller DR. T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis. Journal of Immunology (Baltimore, Md. : 1950). 181: 8784-96. PMID 19050300  0.322
2008 Ha SJ, West EE, Araki K, Smith KA, Ahmed R. Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections. Immunological Reviews. 223: 317-33. PMID 18613845 DOI: 10.1111/J.1600-065X.2008.00638.X  0.571
2008 Pipeling MR, West EE, Osborne CM, Whitlock AB, Dropulic LK, Willett MH, Forman M, Valsamakis A, Orens JB, Moller DR, Lechtzin N, Migueles SA, Connors M, McDyer JF. Differential CMV-specific CD8+ effector T cell responses in the lung allograft predominate over the blood during human primary infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 546-56. PMID 18566421 DOI: 10.4049/Jimmunol.181.1.546  0.51
2008 Pipeling M, West E, Lechtzin N, Migueles S, Connors M, McDyer J. 119: Dissecting CMV-Specific Immunity in High-Risk Lung Transplant Recipients: Differences between the Lung Allograft and Blood Effector Memory T Cells The Journal of Heart and Lung Transplantation. 27: S102. DOI: 10.1016/J.Healun.2007.11.125  0.337
2007 Chen R, Roman J, Guo J, West E, McDyer J, Williams MA, Georas SN. Lysophosphatidic acid modulates the activation of human monocyte-derived dendritic cells. Stem Cells and Development. 15: 797-804. PMID 17253943 DOI: 10.1089/Scd.2006.15.797  0.437
2007 Pipeling M, West E, Osborne C, Migueles S, Connors M, McDyer J. 240: Acquisition of CMV-specific CD8+ T cell memory during primary CMV infection in lung transplant recipients The Journal of Heart and Lung Transplantation. 26: S146. DOI: 10.1016/J.Healun.2006.11.258  0.458
2006 Shlobin OA, West EE, Lechtzin N, Miller SM, Borja M, Orens JB, Dropulic LK, McDyer JF. Persistent cytomegalovirus-specific memory responses in the lung allograft and blood following primary infection in lung transplant recipients. Journal of Immunology (Baltimore, Md. : 1950). 176: 2625-34. PMID 16456025 DOI: 10.4049/Jimmunol.176.4.2625  0.524
2006 West EE, Lavoie TL, Orens JB, Chen ES, Ye SQ, Finkelman FD, Garcia JG, McDyer JF. Pluripotent allospecific CD8+ effector T cells traffic to lung in murine obliterative airway disease. American Journal of Respiratory Cell and Molecular Biology. 34: 108-18. PMID 16195540 DOI: 10.1165/Rcmb.2005-0164Oc  0.522
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