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Rick A. Sperling, Ph.D. - Publications

Affiliations: 
2007 Educational Psychology University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Educational Psychology Education, Hispanic American Studies, Social Psychology, Psychometrics Psychology, Tests and Measurements Education
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Year Citation  Score
2021 Jacobs HIL, Becker JA, Kwong K, Engels-Domínguez N, Prokopiou PC, Papp KV, Properzi M, Hampton OL, d'Oleire Uquillas F, Sanchez JS, Rentz DM, El Fakhri G, Normandin MD, Price JC, Bennett DA, ... Sperling RA, et al. In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer's disease pathology and cognitive decline. Science Translational Medicine. 13: eabj2511. PMID 34550726 DOI: 10.1126/scitranslmed.abj2511  0.339
2021 Ngolab J, Donohue M, Belsha A, Salazar J, Cohen P, Jaiswal S, Tan V, Gessert D, Korouri S, Aggarwal NT, Alber J, Johnson K, Jicha G, van Dyck C, Lah J, ... ... Sperling RA, et al. Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12199. PMID 34430703 DOI: 10.1002/dad2.12199  0.303
2021 Mayblyum DV, Becker JA, Jacobs HIL, Buckley RF, Schultz AP, Sepulcre J, Sanchez JS, Rubinstein ZB, Katz SR, Moody KA, Vannini P, Papp KV, Rentz DM, Price JC, Sperling RA, et al. Comparing PET and MRI Biomarkers Predicting Cognitive Decline in Preclinical Alzheimer Disease. Neurology. PMID 33952655 DOI: 10.1212/WNL.0000000000012108  0.305
2021 Belloy ME, Eger SJ, Le Guen Y, Napolioni V, Deters KD, Yang HS, Scelsi MA, Porter T, James SN, Wong A, Schott JM, Sperling RA, Laws SM, Mormino EC, He Z, et al. KL∗VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗4 carriers. Neurobiology of Aging. 101: 123-129. PMID 33610961 DOI: 10.1016/j.neurobiolaging.2021.01.008  0.329
2021 Guzmán-Vélez E, Zetterberg H, Fox-Fuller JT, Vila-Castelar C, Sanchez JS, Baena A, Garcia-Ospina G, Aguillon D, Pardilla-Delgado E, Gatchel JR, Sperling RA, Johnson K, Reiman EM, Blennow K, Lopera F, et al. Associations between plasma neurofilament light, in vivo brain pathology, and cognition in non-demented individuals with autosomal-dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33527648 DOI: 10.1002/alz.12248  0.351
2021 Sanchez JS, Becker JA, Jacobs HIL, Hanseeuw BJ, Jiang S, Schultz AP, Properzi MJ, Katz SR, Beiser A, Satizabal CL, O'Donnell A, DeCarli C, Killiany R, El Fakhri G, Normandin MD, ... ... Sperling RA, et al. The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography. Science Translational Medicine. 13. PMID 33472953 DOI: 10.1126/scitranslmed.abc0655  0.36
2021 Sanchez JS, Hanseeuw BJ, Lopera F, Sperling RA, Baena A, Bocanegra Y, Aguillon D, Guzmán-Vélez E, Pardilla-Delgado E, Ramirez-Gomez L, Vila-Castelar C, Martinez JE, Fox-Fuller JT, Ramos C, Ochoa-Escudero M, et al. Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study. Alzheimer's Research & Therapy. 13: 27. PMID 33451357 DOI: 10.1186/s13195-020-00765-5  0.358
2021 Papp KV, Rentz DM, Maruff P, Sun CK, Raman R, Donohue MC, Schembri A, Stark C, Yassa MA, Wessels AM, Yaari R, Holdridge KC, Aisen PS, Sperling RA. The Computerized Cognitive Composite (C3) in an Alzheimer's Disease Secondary Prevention Trial. The Journal of Prevention of Alzheimer's Disease. 8: 59-67. PMID 33336226 DOI: 10.14283/jpad.2020.38  0.357
2020 Samaroo A, Amariglio RE, Burnham S, Sparks P, Properzi M, Schultz AP, Buckley R, Johnson KA, Sperling RA, Rentz DM, Papp KV. Diminished Learning Over Repeated Exposures (LORE) in preclinical Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12132. PMID 33426266 DOI: 10.1002/dad2.12132  0.311
2020 Chhatwal JP, Schultz AP, Dang Y, Ostaszewski B, Liu L, Yang HS, Johnson KA, Sperling RA, Selkoe DJ. Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals. Nature Communications. 11: 6024. PMID 33247134 DOI: 10.1038/s41467-020-19543-w  0.343
2020 Farrell ME, Jiang S, Schultz AP, Properzi MJ, Price JC, Becker JA, Jacobs HIL, Hanseeuw BJ, Rentz DM, Villemagne VL, Papp KV, Mormino EC, Betensky RA, Johnson KA, Sperling RA, et al. Defining the lowest threshold for amyloid-PET to predict future cognitive decline and amyloid accumulation. Neurology. PMID 33199430 DOI: 10.1212/WNL.0000000000011214  0.307
2020 Dubbelman MA, Jutten RJ, Tomaszewski Farias SE, Amariglio RE, Buckley RF, Visser PJ, Rentz DM, Johnson KA, Properzi MJ, Schultz A, Donovan N, Gatchell JR, Teunissen CE, Van Berckel BNM, Van der Flier WM, ... Sperling RA, et al. Decline in cognitively complex everyday activities accelerates along the Alzheimer's disease continuum. Alzheimer's Research & Therapy. 12: 138. PMID 33121534 DOI: 10.1186/s13195-020-00706-2  0.374
2020 Jutten RJ, Sikkes SAM, Amariglio RE, Buckley RF, Properzi MJ, Marshall GA, Rentz DM, Johnson KA, Teunissen CE, Van Berckel BNM, Van der Flier WM, Scheltens P, Sperling RA, Papp KV, et al. Identifying Sensitive Measures of Cognitive Decline at Different Clinical Stages of Alzheimer's Disease. Journal of the International Neuropsychological Society : Jins. 1-13. PMID 33046162 DOI: 10.1017/S1355617720000934  0.375
2020 Hampton OL, Buckley RF, Manning LK, Scott MR, Properzi MJ, Peña-Gómez C, Jacobs HIL, Chhatwal JP, Johnson KA, Sperling RA, Schultz AP. Resting-state functional connectivity and amyloid burden influence longitudinal cortical thinning in the default mode network in preclinical Alzheimer's disease. Neuroimage. Clinical. 28: 102407. PMID 32942175 DOI: 10.1016/J.Nicl.2020.102407  0.304
2020 Walter S, Langford OG, Clanton TB, Jimenez-Maggiora GA, Raman R, Rafii MS, Shaffer EJ, Sperling RA, Cummings JL, Aisen PS. The Trial-Ready Cohort for Preclinical and Prodromal Alzheimer's Disease (TRC-PAD): Experience from the First 3 Years. The Journal of Prevention of Alzheimer's Disease. 7: 234-241. PMID 32920625 DOI: 10.14283/jpad.2020.47  0.326
2020 Aisen PS, Sperling RA, Cummings J, Donohue MC, Langford O, Jimenez-Maggiora GA, Rissman RA, Rafii MS, Walter S, Clanton T, Raman R. The Trial-Ready Cohort for Preclinical/Prodromal Alzheimer's Disease (TRC-PAD) Project: An Overview. The Journal of Prevention of Alzheimer's Disease. 7: 208-212. PMID 32920621 DOI: 10.14283/jpad.2020.45  0.324
2020 Vila-Castelar C, Muñoz N, Papp KV, Amariglio RE, Baena A, Guzmán-Vélez E, Bocanegra Y, Sanchez JS, Reiman EM, Johnson KA, Sperling RA, Lopera F, Rentz DM, Quiroz YT. The Latin American Spanish version of the Face-Name Associative Memory Exam is sensitive to cognitive and pathological changes in preclinical autosomal dominant Alzheimer's disease. Alzheimer's Research & Therapy. 12: 104. PMID 32912283 DOI: 10.1186/s13195-020-00671-w  0.339
2020 Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, ... ... Sperling RA, et al. Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain : a Journal of Neurology. 143: 2561-2575. PMID 32844198 DOI: 10.1093/Brain/Awaa209  0.32
2020 Grill JD, Raman R, Ernstrom K, Sultzer DL, Burns JM, Donohue MC, Johnson KA, Aisen PS, Sperling RA, Karlawish J. Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment. Jama Neurology. PMID 32777010 DOI: 10.1001/Jamaneurol.2020.2734  0.338
2020 Scott MR, Hampton OL, Buckley RF, Chhatwal JP, Hanseeuw BJ, Jacobs HIL, Properzi MJ, Sanchez JS, Johnson KA, Sperling RA, Schultz AP. Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults. Neuroimage. 116991. PMID 32512123 DOI: 10.1016/J.Neuroimage.2020.116991  0.325
2020 Insel PS, Donohue MC, Sperling R, Hansson O, Mattsson-Carlgren N. The A4 study: β-amyloid and cognition in 4432 cognitively unimpaired adults. Annals of Clinical and Translational Neurology. PMID 32315118 DOI: 10.1002/Acn3.51048  0.316
2020 Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. The presubiculum links incipient amyloid and tau pathology to memory function in older persons. Neurology. PMID 32273431 DOI: 10.1212/WNL.0000000000009362  0.333
2020 Rabin JS, Shirzadi Z, Swardfager W, MacIntosh BJ, Schultz A, Yang HS, Buckley RF, Gatchel JR, Kirn D, Pruzin JJ, Hedden T, Lipsman N, Rentz DM, Black SE, Johnson KA, ... Sperling RA, et al. Amyloid-beta burden predicts prospective decline in body mass index in clinically normal adults. Neurobiology of Aging. PMID 32249013 DOI: 10.1016/J.Neurobiolaging.2020.03.002  0.331
2020 Biddle KD, Jacobs HIL, d'Oleire Uquillas F, Zide BS, Kirn DR, Properzi MR, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Associations of Widowhood and β-Amyloid With Cognitive Decline in Cognitively Unimpaired Older Adults. Jama Network Open. 3: e200121. PMID 32101313 DOI: 10.1001/jamanetworkopen.2020.0121  0.328
2020 Putcha D, Dickerson BC, Brickhouse M, Johnson KA, Sperling RA, Papp KV. Word retrieval across the biomarker-confirmed Alzheimer's disease syndromic spectrum. Neuropsychologia. 107391. PMID 32057937 DOI: 10.1016/j.neuropsychologia.2020.107391  0.32
2020 Vila-Castelar C, Muñoz N, Papp K, Amariglio R, Baena A, Guzmán-Vélez E, Bocanegra Y, Reiman E, Johnson K, Sperling R, Lopera F, Rentz D, Quiroz Y. A-05 The Latin American Spanish Version of the Face-Name Associative Memory Exam is Sensitive to Cognitive and Pathological Changes in Preclinical Autosomal Dominant Alzheimer’s Disease Archives of Clinical Neuropsychology. 35: 778-778. DOI: 10.1093/arclin/acaa067.05  0.34
2020 Davidow J, Biddle K, Johnson K, Sperling R, Donovan N. INTERACTIVE ASSOCIATION OF LIVING ALONE AND AMYLOID-Β BURDEN WITH LONGITUDINAL COGNITION IN COGNITIVELY UNIMPAIRED OLDER ADULTS The American Journal of Geriatric Psychiatry. 28: S76. DOI: 10.1016/J.Jagp.2020.01.102  0.348
2020 Farrell ME, Papp KV, Jacobs HI, Buckley RF, Properzi MJ, Schultz AP, Hanseeuw B, Rentz DM, Johnson KA, Sperling RA. Distinct contributions of longitudinal tau and amyloid to decline in various cognitive domains in preclinical AD Alzheimer's & Dementia. 16. DOI: 10.1002/alz.046075  0.335
2020 Buckley RF, Chou HL, Properzi MJ, Papp KV, Chhatwal JP, Rentz D, Johnson KA, Sperling RA, Schultz AP. Are amyloid and tau synergistic? How to interpret an amyloid/tau interaction on cognitive decline in clinically normal adults Alzheimer's & Dementia. 16. DOI: 10.1002/alz.044310  0.327
2019 Gatchel JR, Lopera F, Norton DJ, Baena A, Guzman-Velez E, Sanchez JS, d'Oleire Uquillas F, Schultz A, Vannini P, Artola A, Amariglio RE, Rentz DM, Tariot PN, Reiman EM, Johnson KA, ... Sperling RA, et al. Association of subjective cognitive decline with markers of brain pathology in preclinical autosomal dominant Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 31874859 DOI: 10.1136/Jnnp-2019-321205  0.399
2019 Greenberg SM, Bacskai BJ, Hernandez-Guillamon M, Pruzin J, Sperling R, van Veluw SJ. Cerebral amyloid angiopathy and Alzheimer disease - one peptide, two pathways. Nature Reviews. Neurology. PMID 31827267 DOI: 10.1038/S41582-019-0281-2  0.303
2019 Jack CR, Holtzman DM, Sperling R. Dementia is not synonymous with Alzheimer's disease. Science Translational Medicine. 11. PMID 31826979 DOI: 10.1126/Scitranslmed.Aav0511  0.316
2019 Papp KV, Buckley R, Mormino E, Maruff P, Villemagne VL, Masters CL, Johnson KA, Rentz DM, Sperling RA, Amariglio RE. Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31759879 DOI: 10.1016/J.Jalz.2019.09.074  0.375
2019 d'Oleire Uquillas F, Jacobs HIL, Schultz AP, Hanseeuw BJ, Buckley RF, Sepulcre J, Pascual-Leone A, Donovan NJ, Johnson KA, Sperling RA, Vannini P. Functional and Pathological Correlates of Judgments of Learning in Cognitively Unimpaired Older Adults. Cerebral Cortex (New York, N.Y. : 1991). PMID 31696223 DOI: 10.1093/cercor/bhz217  0.331
2019 Arboleda-Velasquez JF, Lopera F, O'Hare M, Delgado-Tirado S, Marino C, Chmielewska N, Saez-Torres KL, Amarnani D, Schultz AP, Sperling RA, Leyton-Cifuentes D, Chen K, Baena A, Aguillon D, Rios-Romenets S, et al. Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report. Nature Medicine. PMID 31686034 DOI: 10.1038/S41591-019-0611-3  0.338
2019 Buckley RF, Sikkes S, Villemagne VL, Mormino EC, Rabin JS, Burnham S, Papp KV, Doré V, Masters CL, Properzi MJ, Schultz AP, Johnson KA, Rentz DM, Sperling RA, Amariglio RE. Using subjective cognitive decline to identify high global amyloid in community-based samples: A cross-cohort study. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 670-678. PMID 31673597 DOI: 10.1016/j.dadm.2019.08.004  0.317
2019 Rabin JS, Klein H, Kirn DR, Schultz AP, Yang HS, Hampton O, Jiang S, Buckley RF, Viswanathan A, Hedden T, Pruzin J, Yau WW, Guzmán-Vélez E, Quiroz YT, Properzi M, ... ... Sperling RA, et al. Associations of Physical Activity and β-Amyloid With Longitudinal Cognition and Neurodegeneration in Clinically Normal Older Adults. Jama Neurology. PMID 31312836 DOI: 10.1001/Jamaneurol.2019.1879  0.341
2019 Biddle KD, Uquillas FD, Jacobs HIL, Zide B, Kirn DR, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Social Engagement and Amyloid-β-Related Cognitive Decline in Cognitively Normal Older Adults. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 31248770 DOI: 10.1016/j.jagp.2019.05.005  0.327
2019 Rabin JS, Perea RD, Buckley RF, Johnson KA, Sperling RA, Hedden T. Synergism between fornix microstructure and beta amyloid accelerates memory decline in clinically normal older adults. Neurobiology of Aging. 81: 38-46. PMID 31207468 DOI: 10.1016/j.neurobiolaging.2019.05.005  0.324
2019 Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, ... ... Sperling RA, et al. Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study. Jama Neurology. PMID 31157827 DOI: 10.1001/Jamaneurol.2019.1424  0.374
2019 Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, ... ... Sperling RA, et al. Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain : a Journal of Neurology. PMID 31039256 DOI: 10.1093/Brain/Awz099  0.32
2019 Fuller JT, Cronin-Golomb A, Gatchel JR, Norton DJ, Guzmán-Vélez E, Jacobs HIL, Hanseeuw B, Pardilla-Delgado E, Artola A, Baena A, Bocanegra Y, Kosik KS, Chen K, Tariot PN, Johnson K, ... Sperling RA, et al. Biological and Cognitive Markers of Presenilin1 E280A Autosomal Dominant Alzheimer's Disease: A Comprehensive Review of the Colombian Kindred. The Journal of Prevention of Alzheimer's Disease. 6: 112-120. PMID 30756118 DOI: 10.14283/jpad.2019.6  0.359
2019 Hanseeuw BJ, Lopera F, Sperling RA, Norton DJ, Guzman-Velez E, Baena A, Pardilla-Delgado E, Schultz AP, Gatchel J, Jin D, Chen K, Reiman EM, Johnson KA, Quiroz YT. Striatal amyloid is associated with tauopathy and memory decline in familial Alzheimer's disease. Alzheimer's Research & Therapy. 11: 17. PMID 30717814 DOI: 10.1186/S13195-019-0468-1  0.316
2019 Halawa OA, Gatchel JR, Amariglio RE, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Inferior and medial temporal tau and cortical amyloid are associated with daily functional impairment in Alzheimer's disease. Alzheimer's Research & Therapy. 11: 14. PMID 30704519 DOI: 10.1186/s13195-019-0471-6  0.396
2019 Tan CH, Bonham LW, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Yokoyama JS, Rabinovici GD, Miller BL, Yaffe K, Schellenberg GD, Kauppi K, Holland D, McEvoy LK, ... ... Sperling RA, et al. Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration. Brain : a Journal of Neurology. PMID 30689776 DOI: 10.1093/Brain/Awy327  0.356
2019 Marshall GA, Gatchel JR, Donovan NJ, Muniz MC, Schultz AP, Becker JA, Chhatwal JP, Hanseeuw BJ, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA. Regional Tau Correlates of Instrumental Activities of Daily Living and Apathy in Mild Cognitive Impairment and Alzheimer's Disease Dementia. Journal of Alzheimer's Disease : Jad. 67: 757-768. PMID 30689584 DOI: 10.3233/Jad-170578  0.384
2019 Jagust W, Jack CR, Bennett DA, Blennow K, Haeberlein SB, Holtzman DM, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, ... ... Sperling R, et al. "Alzheimer's disease" is neither "Alzheimer's clinical syndrome" nor "dementia". Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 15: 153-157. PMID 30642435 DOI: 10.1016/J.Jalz.2018.11.002  0.306
2019 Yang H, Ge T, Finucane H, De Jager PL, Sperling RA. P4-496: MYELOID CELL-SPECIFIC ALZHEIMER'S DISEASE POLYGENIC RISK SCORE PREDICTS NEURODEGENERATION AND Aβ-RELATED COGNITIVE DECLINE IN COGNITIVELY NORMAL OLDER ADULTS Alzheimer's & Dementia. 15: P1503-P1504. DOI: 10.1016/j.jalz.2019.08.042  0.35
2019 Papp KV, Buckley RF, Mormino EC, Maruff P, Villemagne VL, Masters CL, Johnson KA, Rentz D, Sperling RA, Amariglio R. F2-03-01: CLINICAL MEANINGFULNESS OF SHORT-TERM COGNITIVE DECLINE ON THE PRECLINICAL ALZHEIMER'S COGNITIVE COMPOSITE-5 (PACC-5) IN NORMAL OLDER ADULTS WITH ELEVATED β-AMYLOID Alzheimer's & Dementia. 15: P518-P519. DOI: 10.1016/j.jalz.2019.06.4424  0.315
2019 Sikkes SA, Gatchel JR, Buckley RF, van de Wiel MA, Rentz DM, Johnson KA, Sperling RA, Amariglio R. P4-353: SPECIFIC FEATURES OF SUBJECTIVE COGNITIVE DECLINE ARE RELATED TO AMYLOID AND TAU PATHOLOGY IN COGNITIVELY HEALTHY OLDER ADULTS Alzheimer's & Dementia. 15: P1433-P1434. DOI: 10.1016/j.jalz.2019.06.4024  0.32
2019 Papp KV, Buckley RF, Mormino EC, Maruff P, Villemagne VL, Masters CL, Johnson KA, Rentz DM, Sperling RA, Amariglio R. P3-031: CLINICAL MEANINGFULNESS OF SHORT-TERM COGNITIVE DECLINE ON THE PRECLINICAL ALZHEIMER'S COGNITIVE COMPOSITE-5 (PACC-5) IN NORMAL OLDER ADULTS WITH ELEVATED β-AMYLOID Alzheimer's & Dementia. 15: P937-P938. DOI: 10.1016/J.Jalz.2019.06.3057  0.327
2019 Jacobs HI, Becker A, Sperling RA, Guzman-Velez E, Baena A, Uquillas Fd, Artola A, Pardilla-Delgado E, Gatchel JR, Reiman EM, Johnson KA, Lopera F, Quiroz YT. P2-425: LOCUS COERULEUS INTENSITY IS ASSOCIATED WITH EARLY AMYLOID AND TAU PATHOLOGY IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P774-P775. DOI: 10.1016/J.Jalz.2019.06.2832  0.317
2018 Rabin JS, Yang HS, Schultz AP, Hanseeuw BJ, Hedden T, Viswanathan A, Gatchel JR, Marshall GA, Kilpatrick E, Klein H, Rao V, Buckley RF, Yau WW, Kirn DR, Rentz DM, ... ... Sperling RA, et al. Vascular risk and β-amyloid are synergistically associated with cortical tau. Annals of Neurology. PMID 30565287 DOI: 10.1002/Ana.25399  0.325
2018 d'Oleire Uquillas F, Jacobs HIL, Biddle KD, Properzi M, Hanseeuw B, Schultz AP, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Regional tau pathology and loneliness in cognitively normal older adults. Translational Psychiatry. 8: 282. PMID 30563962 DOI: 10.1038/s41398-018-0345-x  0.374
2018 Sperling RA, Mormino EC, Schultz AP, Betensky RA, Papp KV, Amariglio RE, Hanseeuw BJ, Buckley R, Chhatwal J, Hedden T, Marshall GA, Quiroz YT, Donovan NJ, Jackson J, Gatchel JR, et al. The impact of Aβ and tau on prospective cognitive decline in older individuals. Annals of Neurology. PMID 30549303 DOI: 10.1002/Ana.25395  0.399
2018 Huijbers W, Schultz AP, Papp KV, LaPoint MR, Hanseeuw B, Chhatwal JP, Hedden T, Johnson KA, Sperling RA. Tau accumulation in clinically normal older adults is associated with hippocampal hyperactivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30482786 DOI: 10.1523/Jneurosci.1397-18.2018  0.363
2018 McDade E, Wang G, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier K, Xiong C, Allegri R, ... ... Sperling RA, et al. Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease. Neurology. PMID 30217935 DOI: 10.1212/Wnl.0000000000006277  0.341
2018 Hanseeuw BJ, Jonas V, Jackson J, Betensky RA, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Association of anxiety with subcortical amyloidosis in cognitively normal older adults. Molecular Psychiatry. PMID 30116029 DOI: 10.1038/s41380-018-0214-2  0.302
2018 Guzmán-Vélez E, Jaimes S, Aguirre-Acevedo DC, Norton DJ, Papp KV, Amariglio R, Rentz D, Baena A, Henao E, Tirado V, Muñoz C, Giraldo M, Sperling RA, Lopera F, Quiroz YT. A Three-Factor Structure of Cognitive Functioning Among Carriers and Non-Carriers of Autosomal-Dominant Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30040714 DOI: 10.1093/Arclin/Acw043.34  0.36
2018 Munro CE, Donovan NJ, Amariglio RE, Papp KV, Marshall GA, Rentz DM, Pascual-Leone A, Sperling RA, Locascio JJ, Vannini P. The Impact of Awareness of and Concern About Memory Performance on the Prediction of Progression From Mild Cognitive Impairment to Alzheimer Disease Dementia. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 29866588 DOI: 10.1016/j.jagp.2018.04.008  0.375
2018 Buckley RF, Mormino EC, Amariglio RE, Properzi MJ, Rabin JS, Lim YY, Papp KV, Jacobs HIL, Burnham S, Hanseeuw BJ, Doré V, Dobson A, Masters CL, Waller M, Rowe CC, ... ... Sperling RA, et al. Sex, amyloid, and APOE ε4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29803541 DOI: 10.1016/J.Jalz.2018.04.010  0.344
2018 Rabin JS, Schultz AP, Hedden T, Viswanathan A, Marshall GA, Kilpatrick E, Klein H, Buckley RF, Yang HS, Properzi M, Rao V, Kirn DR, Papp KV, Rentz DM, Johnson KA, ... Sperling RA, et al. Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study. Jama Neurology. PMID 29799986 DOI: 10.1001/Jamaneurol.2018.1123  0.344
2018 Jack CR, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, Holtzman DM, Jagust W, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, ... ... Sperling R, et al. NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 14: 535-562. PMID 29653606 DOI: 10.1016/J.Jalz.2018.02.018  0.375
2018 Ge T, Sabuncu MR, Smoller JW, Sperling RA, Mormino EC. Dissociable influences ofε4 and polygenic risk of AD dementia on amyloid and cognition. Neurology. PMID 29592889 DOI: 10.1212/Wnl.0000000000005415  0.339
2018 Chhatwal JP, Schultz AP, Johnson KA, Hedden T, Jaimes S, Benzinger TLS, Jack C, Ances BM, Ringman JM, Marcus DS, Ghetti B, Farlow MR, Danek A, Levin J, Yakushev I, ... ... Sperling RA, et al. Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing. Brain : a Journal of Neurology. PMID 29522171 DOI: 10.1093/Brain/Awy053  0.305
2018 Quiroz YT, Sperling RA, Norton DJ, Baena A, Arboleda-Velasquez JF, Cosio D, Schultz A, Lapoint M, Guzman-Velez E, Miller JB, Kim LA, Chen K, Tariot PN, Lopera F, Reiman EM, et al. Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease. Jama Neurology. PMID 29435558 DOI: 10.1001/Jamaneurol.2017.4907  0.342
2018 Jacobs HIL, Hedden T, Schultz AP, Sepulcre J, Perea RD, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals. Nature Neuroscience. PMID 29403032 DOI: 10.1038/s41593-018-0070-z  0.328
2018 d'Oleire Uquillas F, Jacobs HIL, Hanseeuw B, Marshall GA, Properzi M, Schultz AP, LaPoint MR, Johnson KA, Sperling RA, Vannini P. Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals. Neuroimage. Clinical. 17: 388-396. PMID 29159051 DOI: 10.1016/j.nicl.2017.10.034  0.365
2018 Uquillas Fd, Jacobs HIL, Hanseeuw BJ, Sikkes SAM, Marshall GA, Pascual-Leone A, Johnson KA, Sperling RA, Vannini P. P3-290: Amyloid Pathology Explains Unawareness Of Memory Deficits Above And Beyond Cortical Thickness In Individuals With Mild Cognitive Impairment Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1650  0.303
2017 Papp KV, Rentz DM, Orlovsky I, Sperling RA, Mormino EC. Optimizing the preclinical Alzheimer's cognitive composite with semantic processing: The PACC5. Alzheimer's & Dementia (New York, N. Y.). 3: 668-677. PMID 29264389 DOI: 10.1016/j.trci.2017.10.004  0.349
2017 Buckley RF, Sparks KP, Papp KV, Dekhtyar M, Martin C, Burnham S, Sperling RA, Rentz DM. Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries. The Journal of Prevention of Alzheimer's Disease. 4: 3-11. PMID 29188853 DOI: 10.14283/jpad.2017.1  0.33
2017 Jackson JD, Rentz DM, Aghjayan SL, Buckley RF, Meneide TF, Sperling RA, Amariglio RE. Subjective cognitive concerns are associated with objective memory performance in Caucasian but not African-American persons. Age and Ageing. 46: 988-993. PMID 29088363 DOI: 10.1093/ageing/afx077  0.337
2017 Dumurgier J, Hanseeuw BJ, Hatling FB, Judge KA, Schultz AP, Chhatwal JP, Blacker D, Sperling RA, Johnson KA, Hyman BT, Gómez-Isla T. Alzheimer's Disease Biomarkers and Future Decline in Cognitive Normal Older Adults. Journal of Alzheimer's Disease : Jad. PMID 29036824 DOI: 10.3233/Jad-170511  0.358
2017 Buckley RF, Hanseeuw B, Schultz AP, Vannini P, Aghjayan SL, Properzi MJ, Jackson JD, Mormino EC, Rentz DM, Sperling RA, Johnson KA, Amariglio RE. Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global β-Amyloid Burden. Jama Neurology. PMID 28973551 DOI: 10.1001/jamaneurol.2017.2216  0.372
2017 Gatchel JR, Donovan NJ, Locascio JJ, Schultz AP, Becker JA, Chhatwal J, Papp KV, Amariglio RE, Rentz DM, Blacker D, Sperling RA, Johnson KA, Marshall GA. Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study. Journal of Alzheimer's Disease : Jad. PMID 28697559 DOI: 10.3233/Jad-170001  0.303
2017 Vannini P, Hanseeuw B, Munro CE, Amariglio RE, Marshall GA, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA. Anosognosia for memory deficits in mild cognitive impairment: Insight into the neural mechanism using functional and molecular imaging. Neuroimage. Clinical. 15: 408-414. PMID 28616381 DOI: 10.1016/j.nicl.2017.05.020  0.316
2017 Donohue MC, Sperling RA, Petersen R, Sun CK, Weiner MW, Aisen PS. Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons. Jama. 317: 2305-2316. PMID 28609533 DOI: 10.1001/Jama.2017.6669  0.313
2017 Buckley RF, Schultz AP, Hedden T, Papp KV, Hanseeuw BJ, Marshall G, Sepulcre J, Smith EE, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Functional network integrity presages cognitive decline in preclinical Alzheimer disease. Neurology. PMID 28592457 DOI: 10.1212/Wnl.0000000000004059  0.333
2017 Sepulcre J, Grothe MJ, Sabuncu M, Chhatwal J, Schultz AP, Hanseeuw B, El Fakhri G, Sperling R, Johnson KA. Hierarchical Organization of Tau and Amyloid Deposits in the Cerebral Cortex. Jama Neurology. PMID 28558094 DOI: 10.1001/Jamaneurol.2017.0263  0.309
2017 Gatchel JR, Donovan NJ, Locascio JJ, Becker JA, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Regional 18F-Fluorodeoxyglucose Hypometabolism is Associated with Higher Apathy Scores Over Time in Early Alzheimer Disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 28410856 DOI: 10.1016/j.jagp.2016.12.017  0.384
2017 Vannini P, Amariglio R, Hanseeuw B, Johnson KA, McLaren DG, Chhatwal J, Pascual-Leone A, Rentz D, Sperling RA. Memory self-awareness in the preclinical and prodromal stages of Alzheimer's disease. Neuropsychologia. PMID 28385579 DOI: 10.1016/J.Neuropsychologia.2017.04.002  0.338
2017 Schultz AP, Chhatwal JP, Hedden T, Mormino EC, Hanseeuw BJ, Sepulcre J, Huijbers W, LaPoint M, Buckley RF, Johnson KA, Sperling RA. Phases of hyper and hypo connectivity in the Default Mode and Salience networks track with amyloid and Tau in clinically normal individuals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28314821 DOI: 10.1523/Jneurosci.3263-16.2017  0.315
2017 Papp KV, Rentz DM, Mormino EC, Schultz AP, Amariglio RE, Quiroz Y, Johnson KA, Sperling RA. Cued memory decline in biomarker-defined preclinical Alzheimer disease. Neurology. PMID 28283594 DOI: 10.1212/Wnl.0000000000003812  0.319
2017 Mormino EC, Papp KV, Rentz DM, Donohue MC, Amariglio R, Quiroz YT, Chhatwal J, Marshall GA, Donovan N, Jackson J, Gatchel JR, Hanseeuw BJ, Schultz AP, Aisen PS, Johnson KA, ... Sperling RA, et al. Early and late change on the preclinical Alzheimer's cognitive composite in clinically normal older individuals with elevated β-amyloid. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28253478 DOI: 10.1016/J.Jalz.2017.01.018  0.36
2017 Yang H, Yu L, White CC, Sperling RA, Bennett DA, Schneider JA, De Jager PL. [P2-115]: A TMEM106B LOCUS IS IMPLICATED IN COGNITIVE DECLINE IN ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P650-P651. DOI: 10.1016/J.Jalz.2017.06.765  0.347
2017 Gatchel JR, Norton D, Baena A, Guzman-Velez E, Lopera F, Johnson K, Sperling RA, Marshall GA, Quiroz YT. [IC-P-089]: ANXIETY, SUBJECTIVE COGNITIVE DECLINE, AND CORTICAL AMYLOID IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER's DISEASE: A PRELIMINARY REPORT Alzheimer's & Dementia. 13: P72-P72. DOI: 10.1016/j.jalz.2017.06.2362  0.337
2017 Reiman EM, Kuang X, Luo J, Chen Y, Thiyyagura P, Bauer R, Lee W, Protas H, Goradia DD, Aisen PS, Johnson K, Langbaum JB, Sperling RA, Tariot P, Jagust WJ, et al. [IC-P-041]: SAMPLE SIZES FOR 24-MONTH ALZHEIMER's PREVENTION TRIALS USING BIOMARKER ENDPOINTS IN COGNITIVELY UNIMPAIRED AMYLOID-POSITIVE ADULTS Alzheimer's & Dementia. 13: P36-P37. DOI: 10.1016/J.Jalz.2017.06.2313  0.303
2017 Gatchel JR, Norton DJ, Baena A, Guzman-Velez E, Lopera F, Johnson K, Sperling RA, Marshall GA, Quiroz YT. [P4-243]: ANXIETY, SUBJECTIVE COGNITIVE DECLINE, AND CORTICAL AMYLOID IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER's DISEASE: A PRELIMINARY REPORT Alzheimer's & Dementia. 13: P1369-P1370. DOI: 10.1016/J.Jalz.2017.06.2111  0.359
2016 Molinuevo JL, Rabin LA, Amariglio R, Buckley R, Dubois B, Ellis KA, Ewers M, Hampel H, Klöppel S, Rami L, Reisberg B, Saykin AJ, Sikkes S, Smart CM, Snitz BE, ... Sperling R, et al. Implementation of subjective cognitive decline criteria in research studies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27825022 DOI: 10.1016/J.Jalz.2016.09.012  0.342
2016 Donovan NJ, Okereke OI, Vannini P, Amariglio RE, Rentz DM, Marshall GA, Johnson KA, Sperling RA. Association of Higher Cortical Amyloid Burden With Loneliness in Cognitively Normal Older Adults. Jama Psychiatry. PMID 27806159 DOI: 10.1001/jamapsychiatry.2016.2657  0.373
2016 Rentz DM, Mormino EC, Papp KV, Betensky RA, Sperling RA, Johnson KA. Cognitive resilience in clinical and preclinical Alzheimer's disease: the Association of Amyloid and Tau Burden on cognitive performance. Brain Imaging and Behavior. PMID 27738998 DOI: 10.1007/s11682-016-9640-4  0.343
2016 Aghjayan SL, Buckley RF, Vannini P, Rentz DM, Jackson JD, Sperling RA, Johnson KA, Amariglio RE. The influence of demographic factors on subjective cognitive concerns and beta-amyloid. International Psychogeriatrics. 1-8. PMID 27724996 DOI: 10.1017/S1041610216001502  0.369
2016 Zhang X, Mormino EC, Sun N, Sperling RA, Sabuncu MR, Yeo BT. Bayesian model reveals latent atrophy factors with dissociable cognitive trajectories in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 27702899 DOI: 10.1073/Pnas.1611073113  0.315
2016 Albers AD, Asafu-Adjei J, Delaney MK, Kelly KE, Gomez-Isla T, Blacker D, Johnson KA, Sperling RA, Hyman BT, Betensky RA, Hastings L, Albers MW. Episodic Memory of Odors Stratifies Alzheimer Biomarkers in Normal Elderly. Annals of Neurology. PMID 27696605 DOI: 10.1002/Ana.24792  0.343
2016 Mormino EC, Papp KV, Rentz DM, Schultz AP, LaPoint M, Amariglio R, Hanseeuw B, Marshall GA, Hedden T, Johnson KA, Sperling RA. Heterogeneity in Suspected Non-Alzheimer Disease Pathophysiology Among Clinically Normal Older Individuals. Jama Neurology. PMID 27548655 DOI: 10.1001/jamaneurol.2016.2237  0.311
2016 Buckley RF, Villemagne VL, Masters CL, Ellis KA, Rowe CC, Johnson K, Sperling R, Amariglio R. A Conceptualization of the Utility of Subjective Cognitive Decline in Clinical Trials of Preclinical Alzheimer's Disease. Journal of Molecular Neuroscience : Mn. PMID 27514526 DOI: 10.1007/S12031-016-0810-Z  0.367
2016 Hanseeuw BJ, Schultz AP, Betensky RA, Sperling RA, Johnson KA. Decreased hippocampal metabolism in high-amyloid mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27421609 DOI: 10.1016/j.jalz.2016.06.2357  0.328
2016 Fotiadis P, van Rooden S, van der Grond J, Schultz A, Martinez-Ramirez S, Auriel E, Reijmer Y, van Opstal AM, Ayres A, Schwab KM, Alzheimer's Disease Neuroimaging Initiative Adni, Hedden T, Rosand J, Viswanathan A, Wermer M, ... ... Sperling RA, et al. Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study. The Lancet. Neurology. PMID 27180034 DOI: 10.1016/S1474-4422(16)30030-8  0.321
2016 Rieckmann A, Van Dijk KR, Sperling RA, Johnson KA, Buckner RL, Hedden T. Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease. Neurobiology of Aging. 42: 177-88. PMID 27143434 DOI: 10.1016/j.neurobiolaging.2016.03.016  0.319
2016 Rabinovici GD, Karlawish J, Knopman D, Snyder HM, Sperling R, Carrillo MC. Testing and disclosures related to amyloid imaging and Alzheimer's disease: Common questions and fact sheet summary. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 12: 510-5. PMID 27103054 DOI: 10.1016/J.Jalz.2016.03.002  0.342
2016 Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... Sperling RA, et al. White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the Dominantly Inherited Alzheimer Network. Annals of Neurology. PMID 27016429 DOI: 10.1002/ana.24647  0.305
2016 Jack CR, Knopman DS, Chételat G, Dickson D, Fagan AM, Frisoni GB, Jagust W, Mormino EC, Petersen RC, Sperling RA, van der Flier WM, Villemagne VL, Visser PJ, Vos SJ. Suspected non-Alzheimer disease pathophysiology - concept and controversy. Nature Reviews. Neurology. PMID 26782335 DOI: 10.1038/Nrneurol.2015.251  0.335
2016 Buckley RF, Hanseeuw BJ, Vannini P, Rentz DM, Sperling RA, Johnson K, Amariglio R. TAU BURDEN IS ASSOCIATED WITH SUBJECTIVE COGNITIVE CONCERNS IN THE CONTEXT OF β-AMYLOID BURDEN IN PRECLINICAL AD Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.07.069  0.337
2015 Marshall GA, Dekhtyar M, Bruno JM, Jethwani K, Amariglio RE, Johnson KA, Sperling RA, Rentz DM. The Harvard Automated Phone Task: new performance-based activities of daily living tests for early Alzheimer's disease. The Journal of Prevention of Alzheimer's Disease. 2: 242-253. PMID 26665121 DOI: 10.14283/jpad.2015.72  0.348
2015 Malishkevich A, Marshall GA, Schultz AP, Sperling RA, Aharon-Peretz J, Gozes I. Blood-Borne Activity-Dependent Neuroprotective Protein (ADNP) is Correlated with Premorbid Intelligence, Clinical Stage, and Alzheimer's Disease Biomarkers. Journal of Alzheimer's Disease : Jad. PMID 26639975 DOI: 10.3233/JAD-150799  0.369
2015 Papp KV, Mormino EC, Amariglio RE, Munro C, Dagley A, Schultz AP, Johnson KA, Sperling RA, Rentz DM. Biomarker Validation of a Decline in Semantic Processing in Preclinical Alzheimer's Disease. Neuropsychology. PMID 26595826 DOI: 10.1037/neu0000246  0.346
2015 Johnson KA, Schultz A, Betensky RA, Becker JA, Sepulcre J, Rentz D, Mormino E, Chhatwal J, Amariglio R, Papp K, Marshall G, Albers M, Mauro S, Pepin L, Alverio J, ... ... Sperling R, et al. Tau PET imaging in aging and early Alzheimer's disease. Annals of Neurology. PMID 26505746 DOI: 10.1002/Ana.24546  0.308
2015 Guercio BJ, Donovan NJ, Munro CE, Aghjayan SL, Wigman SE, Locascio JJ, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. The Apathy Evaluation Scale: A Comparison of Subject, Informant, and Clinician Report in Cognitively Normal Elderly and Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. 47: 421-32. PMID 26401564 DOI: 10.3233/JAD-150146  0.357
2015 Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, ... Sperling R, et al. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. PMID 26245925 DOI: 10.1212/Wnl.0000000000001903  0.33
2015 Gidicsin CM, Maye JE, Locascio JJ, Pepin LC, Philiossaint M, Becker JA, Younger AP, Dekhtyar M, Schultz AP, Amariglio RE, Marshall GA, Rentz DM, Hedden T, Sperling RA, Johnson KA. Cognitive activity relates to cognitive performance but not to Alzheimer disease biomarkers. Neurology. 85: 48-55. PMID 26062627 DOI: 10.1212/Wnl.0000000000001704  0.338
2015 Marshall GA, Zoller AS, Lorius N, Amariglio RE, Locascio JJ, Johnson KA, Sperling RA, Rentz DM, For The Alzheimer's Disease Neuroimaging Initiative EY. Functional Activities Questionnaire Items that Best Discriminate and Predict Progression from Clinically Normal to Mild Cognitive Impairment. Current Alzheimer Research. 12: 493-502. PMID 26017560  0.366
2015 Papp KV, Amariglio RE, Mormino EC, Hedden T, Dekhytar M, Johnson KA, Sperling RA, Rentz DM. Free and cued memory in relation to biomarker-defined abnormalities in clinically normal older adults and those at risk for Alzheimer's disease. Neuropsychologia. 73: 169-75. PMID 26002757 DOI: 10.1016/j.neuropsychologia.2015.04.034  0.344
2015 Munro CE, Donovan NJ, Guercio BJ, Wigman SE, Schultz AP, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Neuropsychiatric Symptoms and Functional Connectivity in Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 25854929 DOI: 10.3233/JAD-150017  0.334
2015 Guercio BJ, Donovan NJ, Ward A, Schultz A, Lorius N, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Apathy is associated with lower inferior temporal cortical thickness in mild cognitive impairment and normal elderly individuals. The Journal of Neuropsychiatry and Clinical Neurosciences. 27: e22-7. PMID 25716491 DOI: 10.1176/appi.neuropsych.13060141  0.329
2015 Amariglio RE, Donohue MC, Marshall GA, Rentz DM, Salmon DP, Ferris SH, Karantzoulis S, Aisen PS, Sperling RA. Tracking early decline in cognitive function in older individuals at risk for Alzheimer disease dementia: the Alzheimer's Disease Cooperative Study Cognitive Function Instrument. Jama Neurology. 72: 446-54. PMID 25706191 DOI: 10.1001/Jamaneurol.2014.3375  0.376
2015 Donovan NJ, Hsu DC, Dagley AS, Schultz AP, Amariglio RE, Mormino EC, Okereke OI, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Depressive Symptoms and Biomarkers of Alzheimer's Disease in Cognitively Normal Older Adults. Journal of Alzheimer's Disease : Jad. PMID 25697700 DOI: 10.3233/JAD-142940  0.304
2015 Huijbers W, Mormino EC, Schultz AP, Wigman S, Ward AM, Larvie M, Amariglio RE, Marshall GA, Rentz DM, Johnson KA, Sperling RA. Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression. Brain : a Journal of Neurology. 138: 1023-35. PMID 25678559 DOI: 10.1093/Brain/Awv007  0.331
2015 Replogle JM, Chan G, White CC, Raj T, Winn PA, Evans DA, Sperling RA, Chibnik LB, Bradshaw EM, Schneider JA, Bennett DA, De Jager PL. A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology. Annals of Neurology. 77: 469-77. PMID 25545807 DOI: 10.1002/Ana.24337  0.33
2015 Lorius N, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Viswanathan A, Marshall GA. Vascular disease and risk factors are associated with cognitive decline in the alzheimer disease spectrum. Alzheimer Disease and Associated Disorders. 29: 18-25. PMID 24787033 DOI: 10.1097/WAD.0000000000000043  0.354
2015 Hanseeuw BJ, Schultz AP, Sperling RA, Johnson KA. P4-083: Hippocampal metabolism is decreased in high-amyloid mild cognitive impairment but not in high-amyloid clinically normal elders Alzheimer's & Dementia. 11: P802-P803. DOI: 10.1016/j.jalz.2015.06.1788  0.305
2014 Cavedo E, Lista S, Khachaturian Z, Aisen P, Amouyel P, Herholz K, Jack CR, Sperling R, Cummings J, Blennow K, O'Bryant S, Frisoni GB, Khachaturian A, Kivipelto M, Klunk W, et al. The Road Ahead to Cure Alzheimer's Disease: Development of Biological Markers and Neuroimaging Methods for Prevention Trials Across all Stages and Target Populations. The Journal of Prevention of Alzheimer's Disease. 1: 181-202. PMID 26478889 DOI: 10.14283/jpad.2014.32  0.347
2014 Sperling R, Mormino E, Johnson K. The evolution of preclinical Alzheimer's disease: implications for prevention trials. Neuron. 84: 608-22. PMID 25442939 DOI: 10.1016/J.Neuron.2014.10.038  0.365
2014 Marshall GA, Zoller AS, Kelly KE, Amariglio RE, Locascio JJ, Johnson KA, Sperling RA, Rentz DM, For The Alzheimer's Disease Neuroimaging Initiative. Everyday cognition scale items that best discriminate between and predict progression from clinically normal to mild cognitive impairment. Current Alzheimer Research. 11: 853-61. PMID 25274110  0.329
2014 Mormino EC, Betensky RA, Hedden T, Schultz AP, Amariglio RE, Rentz DM, Johnson KA, Sperling RA. Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. Jama Neurology. 71: 1379-85. PMID 25222039 DOI: 10.1001/jamaneurol.2014.2031  0.318
2014 Zoller AS, Gaal IM, Royer CA, Locascio JJ, Amariglio RE, Blacker D, Okereke OI, Johnson KA, Sperling RA, Rentz DM, Marshall GA. SIST-M-IR activities of daily living items that best discriminate clinically normal elderly from those with mild cognitive impairment. Current Alzheimer Research. 11: 785-91. PMID 25212917 DOI: 10.2174/156720501108140910122220  0.358
2014 Roy K, Pepin LC, Philiossaint M, Lorius N, Becker JA, Locascio JJ, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Regional fluorodeoxyglucose metabolism and instrumental activities of daily living across the Alzheimer's disease spectrum. Journal of Alzheimer's Disease : Jad. 42: 291-300. PMID 24898635 DOI: 10.3233/JAD-131796  0.353
2014 Donohue MC, Sperling RA, Salmon DP, Rentz DM, Raman R, Thomas RG, Weiner M, Aisen PS. The preclinical Alzheimer cognitive composite: measuring amyloid-related decline. Jama Neurology. 71: 961-70. PMID 24886908 DOI: 10.1001/Jamaneurol.2014.803  0.337
2014 Papp KV, Amariglio RE, Dekhtyar M, Roy K, Wigman S, Bamfo R, Sherman J, Sperling RA, Rentz DM. Development of a psychometrically equivalent short form of the Face-Name Associative Memory Exam for use along the early Alzheimer's disease trajectory. The Clinical Neuropsychologist. 28: 771-85. PMID 24815535 DOI: 10.1080/13854046.2014.911351  0.322
2014 Jessen F, Amariglio RE, van Boxtel M, Breteler M, Ceccaldi M, Chételat G, Dubois B, Dufouil C, Ellis KA, van der Flier WM, Glodzik L, van Harten AC, de Leon MJ, McHugh P, Mielke MM, ... ... Sperling RA, et al. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 844-52. PMID 24798886 DOI: 10.1016/J.Jalz.2014.01.001  0.347
2014 Mormino EC, Betensky RA, Hedden T, Schultz AP, Ward A, Huijbers W, Rentz DM, Johnson KA, Sperling RA. Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease. Neurology. 82: 1760-7. PMID 24748674 DOI: 10.1212/Wnl.0000000000000431  0.338
2014 Huijbers W, Mormino EC, Wigman SE, Ward AM, Vannini P, McLaren DG, Becker JA, Schultz AP, Hedden T, Johnson KA, Sperling RA. Amyloid deposition is linked to aberrant entorhinal activity among cognitively normal older adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5200-10. PMID 24719099 DOI: 10.1523/Jneurosci.3579-13.2014  0.322
2014 Donovan NJ, Amariglio RE, Zoller AS, Rudel RK, Gomez-Isla T, Blacker D, Hyman BT, Locascio JJ, Johnson KA, Sperling RA, Marshall GA, Rentz DM. Subjective cognitive concerns and neuropsychiatric predictors of progression to the early clinical stages of Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 22: 1642-51. PMID 24698445 DOI: 10.1016/J.Jagp.2014.02.007  0.341
2014 Marshall GA, Lorius N, Locascio JJ, Hyman BT, Rentz DM, Johnson KA, Sperling RA. Regional cortical thinning and cerebrospinal biomarkers predict worsening daily functioning across the Alzheimer's disease spectrum. Journal of Alzheimer's Disease : Jad. 41: 719-28. PMID 24685624 DOI: 10.3233/Jad-132768  0.334
2014 Sperling RA, Rentz DM, Johnson KA, Karlawish J, Donohue M, Salmon DP, Aisen P. The A4 study: stopping AD before symptoms begin? Science Translational Medicine. 6: 228fs13. PMID 24648338 DOI: 10.1126/Scitranslmed.3007941  0.355
2014 Doraiswamy PM, Sperling RA, Johnson K, Reiman EM, Wong TZ, Sabbagh MN, Sadowsky CH, Fleisher AS, Carpenter A, Joshi AD, Lu M, Grundman M, Mintun MA, Skovronsky DM, Pontecorvo MJ, et al. Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study. Molecular Psychiatry. 19: 1044-51. PMID 24614494 DOI: 10.1038/Mp.2014.9  0.331
2014 Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, et al. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Science Translational Medicine. 6: 226ra30. PMID 24598588 DOI: 10.1126/Scitranslmed.3007901  0.343
2014 Serrano-Pozo A, Qian J, Monsell SE, Blacker D, Gómez-Isla T, Betensky RA, Growdon JH, Johnson KA, Frosch MP, Sperling RA, Hyman BT. Mild to moderate Alzheimer dementia with insufficient neuropathological changes. Annals of Neurology. 75: 597-601. PMID 24585367 DOI: 10.1002/Ana.24125  0.331
2014 Donovan NJ, Wadsworth LP, Lorius N, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Regional cortical thinning predicts worsening apathy and hallucinations across the Alzheimer disease spectrum. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 22: 1168-79. PMID 23890751 DOI: 10.1016/j.jagp.2013.03.006  0.374
2014 Johnson KA, Mormino E, Rentz DM, Schultz A, Becker JA, Sepulcre J, Chhatwal J, Amariglio R, Papp K, Marshall G, Shoup T, Yokell D, Brady T, Hyman B, Vasdev N, ... Sperling R, et al. DT-01-02: TEMPORAL NEOCORTICAL TAU DEPOSITION MEASURED WITH PET IS ASSOCIATED WITH LONGITUDINAL DECLINE IN MEMORY PERFORMANCE AMONG CLINICALLY NORMAL ELDERLY Alzheimer's & Dementia. 10: P280-P280. DOI: 10.1016/J.Jalz.2014.07.150  0.391
2014 Donovan NJ, Hsu D, Dagley A, Schultz A, Amariglio R, Rentz DM, Johnson KA, Sperling RA, Marshall G. P2-154: SUBSYNDROMAL DEPRESSION AND ALZHEIMER'S DISEASE BIOMARKERS IN COGNITIVELY NORMAL ELDERLY Alzheimer's & Dementia. 10: P527-P528. DOI: 10.1016/j.jalz.2014.05.830  0.304
2013 Rentz DM, Parra Rodriguez MA, Amariglio R, Stern Y, Sperling R, Ferris S. Promising developments in neuropsychological approaches for the detection of preclinical Alzheimer's disease: a selective review. Alzheimer's Research & Therapy. 5: 58. PMID 24257331 DOI: 10.1186/Alzrt222  0.335
2013 Marshall GA, Donovan NJ, Lorius N, Gidicsin CM, Maye J, Pepin LC, Becker JA, Amariglio RE, Rentz DM, Sperling RA, Johnson KA. Apathy is associated with increased amyloid burden in mild cognitive impairment. The Journal of Neuropsychiatry and Clinical Neurosciences. 25: 302-7. PMID 24247857 DOI: 10.1176/Appi.Neuropsych.12060156  0.336
2013 Salmon DP, Ferris SH, Thomas RG, Sano M, Cummings JL, Sperling RA, Petersen RC, Aisen PS. Age and apolipoprotein E genotype influence rate of cognitive decline in nondemented elderly. Neuropsychology. 27: 391-401. PMID 23876113 DOI: 10.1037/A0032707  0.329
2013 Sepulcre J, Sabuncu MR, Becker A, Sperling R, Johnson KA. In vivo characterization of the early states of the amyloid-beta network. Brain : a Journal of Neurology. 136: 2239-52. PMID 23801740 DOI: 10.1093/Brain/Awt146  0.327
2013 Sperling R, Johnson K. Biomarkers of Alzheimer disease: current and future applications to diagnostic criteria. Continuum (Minneapolis, Minn.). 19: 325-38. PMID 23558480 DOI: 10.1212/01.CON.0000429181.60095.99  0.338
2013 Carrillo MC, Brashear HR, Logovinsky V, Ryan JM, Feldman HH, Siemers ER, Abushakra S, Hartley DM, Petersen RC, Khachaturian AS, Sperling RA. Can we prevent Alzheimer's disease? Secondary "prevention" trials in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 123-131.e1. PMID 23411394 DOI: 10.1016/J.Jalz.2012.12.004  0.326
2013 Johnson KA, Sperling RA, Gidicsin CM, Carmasin JS, Maye JE, Coleman RE, Reiman EM, Sabbagh MN, Sadowsky CH, Fleisher AS, Murali Doraiswamy P, Carpenter AP, Clark CM, Joshi AD, Lu M, et al. Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: S72-83. PMID 23375563 DOI: 10.1016/J.Jalz.2012.10.007  0.336
2013 Sperling RA, Karlawish J, Johnson KA. Preclinical Alzheimer disease-the challenges ahead. Nature Reviews. Neurology. 9: 54-8. PMID 23183885 DOI: 10.1038/nrneurol.2012.241  0.301
2013 Quiroz YT, Stern CE, Reiman EM, Brickhouse M, Ruiz A, Sperling RA, Lopera F, Dickerson BC. Cortical atrophy in presymptomatic Alzheimer's disease presenilin 1 mutation carriers. Journal of Neurology, Neurosurgery, and Psychiatry. 84: 556-61. PMID 23134660 DOI: 10.1136/Jnnp-2012-303299  0.319
2013 Desikan RS, McEvoy LK, Holland D, Thompson WK, Brewer JB, Aisen PS, Andreassen OA, Hyman BT, Sperling RA, Dale AM. Apolipoprotein E epsilon4 does not modulate amyloid-β-associated neurodegeneration in preclinical Alzheimer disease. Ajnr. American Journal of Neuroradiology. 34: 505-10. PMID 22976236 DOI: 10.3174/Ajnr.A3267  0.307
2013 Vannini P, Hedden T, Huijbers W, Ward A, Johnson KA, Sperling RA. The ups and downs of the posteromedial cortex: age- and amyloid-related functional alterations of the encoding/retrieval flip in cognitively normal older adults. Cerebral Cortex (New York, N.Y. : 1991). 23: 1317-28. PMID 22586140 DOI: 10.1093/Cercor/Bhs108  0.331
2012 Marshall GA, Amariglio RE, Sperling RA, Rentz DM. Activities of daily living: where do they fit in the diagnosis of Alzheimer's disease? Neurodegenerative Disease Management. 2: 483-491. PMID 23585777 DOI: 10.2217/nmt.12.55  0.373
2012 Hedden T, Mormino EC, Amariglio RE, Younger AP, Schultz AP, Becker JA, Buckner RL, Johnson KA, Sperling RA, Rentz DM. Cognitive profile of amyloid burden and white matter hyperintensities in cognitively normal older adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16233-42. PMID 23152607 DOI: 10.1523/JNEUROSCI.2462-12.2012  0.336
2012 Morris JC, Aisen PS, Bateman RJ, Benzinger TL, Cairns NJ, Fagan AM, Ghetti B, Goate AM, Holtzman DM, Klunk WE, McDade E, Marcus DS, Martins RN, Masters CL, Mayeux R, ... ... Sperling RA, et al. Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clinical Investigation. 2: 975-984. PMID 23139856 DOI: 10.4155/Cli.12.93  0.313
2012 Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, et al. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study. The Lancet. Neurology. 11: 1048-56. PMID 23137948 DOI: 10.1016/S1474-4422(12)70228-4  0.34
2012 Amariglio RE, Becker JA, Carmasin J, Wadsworth LP, Lorius N, Sullivan C, Maye JE, Gidicsin C, Pepin LC, Sperling RA, Johnson KA, Rentz DM. Subjective cognitive complaints and amyloid burden in cognitively normal older individuals. Neuropsychologia. 50: 2880-6. PMID 22940426 DOI: 10.1016/J.Neuropsychologia.2012.08.011  0.359
2012 Wadsworth LP, Lorius N, Donovan NJ, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Neuropsychiatric symptoms and global functional impairment along the Alzheimer's continuum. Dementia and Geriatric Cognitive Disorders. 34: 96-111. PMID 22922821 DOI: 10.1159/000342119  0.344
2012 Doraiswamy PM, Sperling RA, Coleman RE, Johnson KA, Reiman EM, Davis MD, Grundman M, Sabbagh MN, Sadowsky CH, Fleisher AS, Carpenter A, Clark CM, Joshi AD, Mintun MA, Skovronsky DM, et al. Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study. Neurology. 79: 1636-44. PMID 22786606 DOI: 10.1212/Wnl.0B013E3182661F74  0.368
2012 Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, ... ... Sperling RA, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. The New England Journal of Medicine. 367: 795-804. PMID 22784036 DOI: 10.1056/Nejmoa1202753  0.321
2012 Desikan RS, McEvoy LK, Thompson WK, Holland D, Brewer JB, Aisen PS, Sperling RA, Dale AM. Amyloid-β--associated clinical decline occurs only in the presence of elevated P-tau. Archives of Neurology. 69: 709-13. PMID 22529247 DOI: 10.1001/Archneurol.2011.3354  0.364
2012 Sabuncu MR, Buckner RL, Smoller JW, Lee PH, Fischl B, Sperling RA. The association between a polygenic Alzheimer score and cortical thickness in clinically normal subjects. Cerebral Cortex (New York, N.Y. : 1991). 22: 2653-61. PMID 22169231 DOI: 10.1093/Cercor/Bhr348  0.315
2012 Vannini P, Hedden T, Becker JA, Sullivan C, Putcha D, Rentz D, Johnson KA, Sperling RA. Age and amyloid-related alterations in default network habituation to stimulus repetition. Neurobiology of Aging. 33: 1237-52. PMID 21334099 DOI: 10.1016/j.neurobiolaging.2011.01.003  0.316
2012 Donovan N, Wadsworth L, Lorius N, Locascio J, Rentz D, Johnson K, Sperling R. P2-236: Regional cortical thinning predicts worsening apathy and hallucinations in mild cognitive impairment and mild Alzheimer's disease dementia Alzheimer's & Dementia. 8: P342-P343. DOI: 10.1016/j.jalz.2012.05.943  0.356
2012 Benzinger T, Blazey T, Koeppe R, Jack C, Raichle M, Su Y, Snyder A, Marcus D, Ringman J, Thompson P, Ghetti B, Saykin A, Salloway S, Correia S, Johnson K, ... Sperling R, et al. Elevated PiB precedes dementia in autosomal dominant Alzheimer's disease: PiB, FDG and atrophy in the DIAN cohort Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.132  0.323
2011 Silverberg NB, Ryan LM, Carrillo MC, Sperling R, Petersen RC, Posner HB, Snyder PJ, Hilsabeck R, Gallagher M, Raber J, Rizzo A, Possin K, King J, Kaye J, Ott BR, et al. Assessment of cognition in early dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: e60-e76. PMID 23559893 DOI: 10.1016/J.Jalz.2011.05.001  0.349
2011 Reiman EM, McKhann GM, Albert MS, Sperling RA, Petersen RC, Blacker D. Clinical impact of updated diagnostic and research criteria for Alzheimer's disease. The Journal of Clinical Psychiatry. 72: e37. PMID 22244033 DOI: 10.4088/Jcp.10087Tx2C  0.32
2011 Holtzman DM, Goate A, Kelly J, Sperling R. Mapping the road forward in Alzheimer's disease. Science Translational Medicine. 3: 114ps48. PMID 22190237 DOI: 10.1126/Scitranslmed.3003529  0.307
2011 Putcha D, Brickhouse M, O'Keefe K, Sullivan C, Rentz D, Marshall G, Dickerson B, Sperling R. Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17680-8. PMID 22131428 DOI: 10.1523/Jneurosci.4740-11.2011  0.382
2011 Sabuncu MR, Desikan RS, Sepulcre J, Yeo BT, Liu H, Schmansky NJ, Reuter M, Weiner MW, Buckner RL, Sperling RA, Fischl B. The dynamics of cortical and hippocampal atrophy in Alzheimer disease. Archives of Neurology. 68: 1040-8. PMID 21825241 DOI: 10.1001/Archneurol.2011.167  0.375
2011 Marshall GA, Olson LE, Frey MT, Maye J, Becker JA, Rentz DM, Sperling RA, Johnson KA. Instrumental activities of daily living impairment is associated with increased amyloid burden. Dementia and Geriatric Cognitive Disorders. 31: 443-50. PMID 21778725 DOI: 10.1159/000329543  0.337
2011 Ewers M, Sperling RA, Klunk WE, Weiner MW, Hampel H. Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia. Trends in Neurosciences. 34: 430-42. PMID 21696834 DOI: 10.1016/J.Tins.2011.05.005  0.377
2011 Marshall GA, Rentz DM, Frey MT, Locascio JJ, Johnson KA, Sperling RA. Executive function and instrumental activities of daily living in mild cognitive impairment and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 300-8. PMID 21575871 DOI: 10.1016/j.jalz.2010.04.005  0.36
2011 Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, Iwatsubo T, Jack CR, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 280-92. PMID 21514248 DOI: 10.1016/J.Jalz.2011.03.003  0.377
2011 Jack CR, Albert MS, Knopman DS, McKhann GM, Sperling RA, Carrillo MC, Thies B, Phelps CH. Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 257-62. PMID 21514247 DOI: 10.1016/J.Jalz.2011.03.004  0.323
2011 Dickerson BC, Stoub TR, Shah RC, Sperling RA, Killiany RJ, Albert MS, Hyman BT, Blacker D, Detoledo-Morrell L. Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults. Neurology. 76: 1395-402. PMID 21490323 DOI: 10.1212/Wnl.0B013E3182166E96  0.338
2011 Drzezga A, Becker JA, Van Dijk KR, Sreenivasan A, Talukdar T, Sullivan C, Schultz AP, Sepulcre J, Putcha D, Greve D, Johnson KA, Sperling RA. Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden. Brain : a Journal of Neurology. 134: 1635-46. PMID 21490054 DOI: 10.1093/brain/awr066  0.328
2011 Becker JA, Hedden T, Carmasin J, Maye J, Rentz DM, Putcha D, Fischl B, Greve DN, Marshall GA, Salloway S, Marks D, Buckner RL, Sperling RA, Johnson KA. Amyloid-β associated cortical thinning in clinically normal elderly. Annals of Neurology. 69: 1032-42. PMID 21437929 DOI: 10.1002/Ana.22333  0.348
2011 Yang W, Lui RL, Gao JH, Chan TF, Yau ST, Sperling RA, Huang X. Independent component analysis-based classification of Alzheimer's disease MRI data. Journal of Alzheimer's Disease : Jad. 24: 775-83. PMID 21321398 DOI: 10.3233/Jad-2011-101371  0.315
2011 Putcha D, O'Keefe K, LaViolette P, O'Brien J, Greve D, Rentz DM, Locascio J, Atri A, Sperling R. Reliability of functional magnetic resonance imaging associative encoding memory paradigms in non-demented elderly adults. Human Brain Mapping. 32: 2027-44. PMID 21259385 DOI: 10.1002/Hbm.21166  0.301
2011 Bateman RJ, Aisen PS, De Strooper B, Fox NC, Lemere CA, Ringman JM, Salloway S, Sperling RA, Windisch M, Xiong C. Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease. Alzheimer's Research & Therapy. 3: 1. PMID 21211070 DOI: 10.1186/Alzrt59  0.31
2011 Pihlajamäki M, O'Keefe K, O'Brien J, Blacker D, Sperling RA. Failure of repetition suppression and memory encoding in aging and Alzheimer's disease. Brain Imaging and Behavior. 5: 36-44. PMID 21161449 DOI: 10.1007/s11682-010-9110-3  0.308
2011 Marshall G, Lorius N, Locascio J, Rentz D, Johnson K, Sperling R. Low CSF Abeta 1-42 is associated with worsening daily functioning in mild cognitive impairment and mild Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.936  0.364
2011 Dickerson B, Albert M, Blacker D, Shah R, DeToledo-Morrell L, Killiany R, Sperling R, Stoub T, Hyman B. O1-07-01: Alzheimer's-signature MRI biomarker predicts likelihood of Alzheimer's dementia in cognitively normal adults Alzheimer's & Dementia. 7: S109-S109. DOI: 10.1016/j.jalz.2011.05.272  0.34
2011 Dickerson B, Stoub T, Shah R, Sperling R, Killiany R, Albert M, Hyman B, Blacker D, DeToledo-Morrell L. IC-P-040: Alzheimer's signature MRI biomarker predicts likelihood of Alzheimer's dementia in cognitively normal adults Alzheimer's & Dementia. 7: S24-S25. DOI: 10.1016/J.Jalz.2011.05.109  0.343
2011 Pihlajamäki M, Sperling RA. Functional MRI in Alzheimer's Disease and Other Dementias The Handbook of Alzheimer's Disease and Other Dementias. 535-556. DOI: 10.1002/9781444344110.ch18  0.314
2010 Desikan RS, Sabuncu MR, Schmansky NJ, Reuter M, Cabral HJ, Hess CP, Weiner MW, Biffi A, Anderson CD, Rosand J, Salat DH, Kemper TL, Dale AM, Sperling RA, Fischl B, et al. Selective disruption of the cerebral neocortex in Alzheimer's disease. Plos One. 5: e12853. PMID 20886094 DOI: 10.1371/Journal.Pone.0012853  0.374
2010 Sperling R, Johnson K. Pro: Can biomarkers be gold standards in Alzheimer's disease? Alzheimer's Research & Therapy. 2: 17. PMID 20587006 DOI: 10.1186/alzrt41  0.356
2010 O'Brien JL, O'Keefe KM, LaViolette PS, DeLuca AN, Blacker D, Dickerson BC, Sperling RA. Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline. Neurology. 74: 1969-76. PMID 20463288 DOI: 10.1212/Wnl.0B013E3181E3966E  0.339
2010 Rentz DM, Locascio JJ, Becker JA, Moran EK, Eng E, Buckner RL, Sperling RA, Johnson KA. Cognition, reserve, and amyloid deposition in normal aging. Annals of Neurology. 67: 353-64. PMID 20373347 DOI: 10.1002/ana.21904  0.322
2010 Sperling RA, Dickerson BC, Pihlajamaki M, Vannini P, LaViolette PS, Vitolo OV, Hedden T, Becker JA, Rentz DM, Selkoe DJ, Johnson KA. Functional alterations in memory networks in early Alzheimer's disease. Neuromolecular Medicine. 12: 27-43. PMID 20069392 DOI: 10.1007/S12017-009-8109-7  0.341
2010 Pihlajamäki M, O' Keefe K, Bertram L, Tanzi RE, Dickerson BC, Blacker D, Albert MS, Sperling RA. Evidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer disease. Alzheimer Disease and Associated Disorders. 24: 28-36. PMID 19571734 DOI: 10.1097/Wad.0B013E3181A785C9  0.326
2009 Pihlajamäki M, Sperling RA. Functional MRI assessment of task-induced deactivation of the default mode network in Alzheimer's disease and at-risk older individuals. Behavioural Neurology. 21: 77-91. PMID 19847047 DOI: 10.3233/BEN-2009-0231  0.349
2009 Dickerson BC, Sperling RA. Large-scale functional brain network abnormalities in Alzheimer's disease: insights from functional neuroimaging. Behavioural Neurology. 21: 63-75. PMID 19847046 DOI: 10.3233/BEN-2009-0227  0.309
2009 Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, Marshall G, Hyman BT, Selkoe DJ, Hedden T, Buckner RL, Becker JA, Johnson KA. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron. 63: 178-88. PMID 19640477 DOI: 10.1016/J.Neuron.2009.07.003  0.348
2009 Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, et al. The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cerebral Cortex (New York, N.Y. : 1991). 19: 497-510. PMID 18632739 DOI: 10.1093/Cercor/Bhn113  0.302
2009 Sperling R, Johnson K, Pontecorvo MJ, Safirstein B, Farmer M, Holub R, Korn R, Spicer K, Doraiswamy M, Reiman EM, Joshi A, Saha K, Flitter M, Clark CM, Skovronsky DM. P1-084: PET imaging of β-amyloid with florpiramine F18 (18F-AV-45): Preliminary results from a phase II study of cognitively normal elderly subjects, individuals with mild cognitive impairment, and patients with a clinical diagnosis of Alzheimer's disease Alzheimer's & Dementia. 5: P197-P197. DOI: 10.1016/J.Jalz.2009.04.088  0.311
2008 Pihlajamäki M, DePeau KM, Blacker D, Sperling RA. Impaired medial temporal repetition suppression is related to failure of parietal deactivation in Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 16: 283-92. PMID 18378553 DOI: 10.1097/JGP.0b013e318162a0a9  0.302
2008 Miller SL, Fenstermacher E, Bates J, Blacker D, Sperling RA, Dickerson BC. Hippocampal activation in adults with mild cognitive impairment predicts subsequent cognitive decline. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 630-5. PMID 17846109 DOI: 10.1136/jnnp.2007.124149  0.315
2008 Pihlajamäki M, Sperling RA. fMRI: Use in early Alzheimer's disease and in clinical trials Future Neurology. 3: 409-421. DOI: 10.2217/14796708.3.4.409  0.368
2007 Dickerson BC, Sperling RA, Hyman BT, Albert MS, Blacker D. Clinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairment. Archives of General Psychiatry. 64: 1443-50. PMID 18056553 DOI: 10.1001/Archpsyc.64.12.1443  0.36
2007 Rentz DM, Huh TJ, Sardinha LM, Moran EK, Becker JA, Daffner KR, Sperling RA, Johnson KA. Intelligence quotient-adjusted memory impairment is associated with abnormal single photon emission computed tomography perfusion. Journal of the International Neuropsychological Society : Jins. 13: 821-31. PMID 17697413 DOI: 10.1017/S1355617707071056  0.315
2007 Sperling R. Functional MRI studies of associative encoding in normal aging, mild cognitive impairment, and Alzheimer's disease. Annals of the New York Academy of Sciences. 1097: 146-55. PMID 17413017 DOI: 10.1196/Annals.1379.009  0.404
2006 Celone KA, Calhoun VD, Dickerson BC, Atri A, Chua EF, Miller SL, DePeau K, Rentz DM, Selkoe DJ, Blacker D, Albert MS, Sperling RA. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10222-31. PMID 17021177 DOI: 10.1523/Jneurosci.2250-06.2006  0.345
2006 Lim Y, Maruff P, Masters CL, Sperling RA, Johnson KA, Mormino BC. P4-118: AV1451 TAU PET, BUT NOT CSF TAU, IS RELATED TO MEMORY DECLINE IN PRECLINICAL AND PRODROMAL ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1484-P1484. DOI: 10.1016/j.jalz.2018.06.2522  0.306
2006 Quiroz YT, Aguero C, Lopera F, Norton DJ, Aguirre-Acevedo DC, Chen K, Baena A, Gatchel JR, Guzman-Velez E, Pardilla-Delgado E, Artola A, Alvarez S, Sperling RA, Reiman EM, Johnson KA. P3-399: ASSOCIATION BETWEEN CORTICAL THINNING AND TAU PATHOLOGY IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1253-P1254. DOI: 10.1016/J.Jalz.2018.06.1761  0.304
2006 DePeau KM, Pihlajamaki M, Diamond EL, Miller SM, Chua EF, Dickerson BC, Albert MS, Blacker D, Sperling RA. IC-P-086: Failure of hippocampal habituation in mild cognitive impairment and Alzheimer's disease Alzheimer's & Dementia. 2: S687-S688. DOI: 10.1016/J.Jalz.2006.05.2291  0.318
2006 DePeau KM, Pihlajamaki M, Diamond EL, Miller SM, Chua EF, Dickerson BC, Albert MS, Blacker D, Sperling RA. P2-381: Failure of hippocampal habituation in mild cognitive impairment and Alzheimer's disease Alzheimer's & Dementia. 2: S357-S358. DOI: 10.1016/j.jalz.2006.05.1221  0.339
2006 Rentz DM, Sardinha LM, Manning LN, Moran EK, Becker JA, Sperling RA, DeKosky ST, Mathis CA, Klunk WE, Fischman AJ, Johnson KA. P2-329: Amyloid burden correlates with cognitive function in normal aging, MCI and AD Alzheimer's & Dementia. 2: S337-S338. DOI: 10.1016/j.jalz.2006.05.1169  0.345
2005 Dickerson BC, Salat DH, Greve DN, Chua EF, Rand-Giovannetti E, Rentz DM, Bertram L, Mullin K, Tanzi RE, Blacker D, Albert MS, Sperling RA. Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD. Neurology. 65: 404-11. PMID 16087905 DOI: 10.1212/01.Wnl.0000171450.97464.49  0.351
2005 Dickerson BC, Sperling RA. Neuroimaging biomarkers for clinical trials of disease-modifying therapies in Alzheimer's disease. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 2: 348-60. PMID 15897955 DOI: 10.1602/neurorx.2.2.348  0.314
2004 Rentz DM, Huh TJ, Faust RR, Budson AE, Scinto LF, Sperling RA, Daffner KR. Use of IQ-adjusted norms to predict progressive cognitive decline in highly intelligent older individuals. Neuropsychology. 18: 38-49. PMID 14744186 DOI: 10.1037/0894-4105.18.1.38  0.333
1996 Sandson TA, O'Connor M, Sperling RA, Edelman RR, Warach S. Noninvasive perfusion MRI in Alzheimer's disease: a preliminary report. Neurology. 47: 1339-42. PMID 8909457 DOI: 10.1212/WNL.47.5.1339  0.312
Low-probability matches (unlikely to be authored by this person)
2011 Maye J, Gidicsin C, Carmasin J, Becker JA, Blacker D, Rentz D, Sperling R, Johnson K. P1-382: Maternal history of dementia is associated with amyloid deposition and brain glucose hypometabolism in cognitively normal and mildly impaired elderly Alzheimer's & Dementia. 7: S234-S235. DOI: 10.1016/J.Jalz.2011.05.663  0.3
2019 Sperling R, Cummings J, Donohue M, Aisen P. Global Alzheimer's Platform Trial Ready Cohorts for the Prevention of Alzheimer's Dementia. The Journal of Prevention of Alzheimer's Disease. 3: 185-187. PMID 29199318 DOI: 10.14283/jpad.2016.108  0.299
2017 Aisen PS, Cummings J, Jack CR, Morris JC, Sperling R, Frölich L, Jones RW, Dowsett SA, Matthews BR, Raskin J, Scheltens P, Dubois B. On the path to 2025: understanding the Alzheimer's disease continuum. Alzheimer's Research & Therapy. 9: 60. PMID 28793924 DOI: 10.1186/S13195-017-0283-5  0.299
2017 Hanseeuw BJ, Betensky RA, Schultz AP, Papp KV, Mormino EC, Sepulcre J, Bark JS, Cosio DM, LaPoint M, Chhatwal JP, Rentz DM, Sperling RA, Johnson K. FDG metabolism associated with tau-amyloid interaction predicts memory decline. Annals of Neurology. PMID 28253546 DOI: 10.1002/Ana.24910  0.299
2014 Vellas B, Sampaio C, Bateman R, Boxer A, Carrillo MC, Cummings J, Dubois B, Hampel H, Katz R, Khachaturian Z, Gauthier S, Johnson K, Karlawish J, Mintun M, Petersen R, ... ... Sperling R, et al. EU./U.S. CTAD Task Force on Alzheimer's Trial Populations. The Journal of Prevention of Alzheimer's Disease. 1: 110-116. PMID 29255837 DOI: 10.14283/jpad.2014.6  0.298
2021 Fox-Fuller JT, Torrico-Teave H, d'Oleire Uquillas F, Chen K, Su Y, Chen Y, Brickhouse M, Sanchez JS, Aguero C, Jacobs HIL, Hampton O, Guzmán-Vélez E, Vila-Castelar C, Aguirre-Acevedo DC, Baena A, ... ... Sperling RA, et al. Cortical thickness across the lifespan in a Colombian cohort with autosomal-dominant Alzheimer's disease: A cross-sectional study. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12233. PMID 34541287 DOI: 10.1002/dad2.12233  0.298
2012 McLaren DG, Sreenivasan A, Diamond EL, Mitchell MB, Van Dijk KR, Deluca AN, O'Brien JL, Rentz DM, Sperling RA, Atri A. Tracking cognitive change over 24 weeks with longitudinal functional magnetic resonance imaging in Alzheimer's disease. Neuro-Degenerative Diseases. 9: 176-86. PMID 22456451 DOI: 10.1159/000335876  0.297
2021 Sperling R, Henley D, Aisen PS, Raman R, Donohue MC, Ernstrom K, Rafii MS, Streffer J, Shi Y, Karcher K, Raghavan N, Tymofyeyev Y, Bogert J, Brashear HR, Novak G, et al. Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial. Jama Neurology. PMID 33464300 DOI: 10.1001/jamaneurol.2020.4857  0.297
2015 Amariglio RE, Mormino EC, Pietras AC, Marshall GA, Vannini P, Johnson KA, Sperling RA, Rentz DM. Subjective cognitive concerns, amyloid-β, and neurodegeneration in clinically normal elderly. Neurology. 85: 56-62. PMID 26048028 DOI: 10.1212/WNL.0000000000001712  0.297
2016 Sepulcre J, Schultz AP, Sabuncu M, Gomez-Isla T, Chhatwal J, Becker A, Sperling R, Johnson KA. In Vivo Tau, Amyloid, and Gray Matter Profiles in the Aging Brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7364-74. PMID 27413148 DOI: 10.1523/Jneurosci.0639-16.2016  0.297
2014 Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, et al. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. The New England Journal of Medicine. 370: 322-33. PMID 24450891 DOI: 10.1056/Nejmoa1304839  0.297
2011 Sperling RA, Jack CR, Black SE, Frosch MP, Greenberg SM, Hyman BT, Scheltens P, Carrillo MC, Thies W, Bednar MM, Black RS, Brashear HR, Grundman M, Siemers ER, Feldman HH, et al. Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 367-85. PMID 21784348 DOI: 10.1016/J.Jalz.2011.05.2351  0.296
2021 Sato K, Ihara R, Suzuki K, Niimi Y, Toda T, Jimenez-Maggiora G, Langford O, Donohue MC, Raman R, Aisen PS, Sperling RA, Iwata A, Iwatsubo T. Predicting amyloid risk by machine learning algorithms based on the A4 screen data: Application to the Japanese Trial-Ready Cohort study. Alzheimer's & Dementia (New York, N. Y.). 7: e12135. PMID 33778148 DOI: 10.1002/trc2.12135  0.296
2013 Papp K, Amariglio R, Sperling R, Bamfo R, Wigman S, Rentz D. P2-273: Semantic memory and its relationship to episodic memory and amyloid burden in cognitively normal (CN) older adults and those with mild cognitive impairment (MCI) Alzheimer's & Dementia. 9: P457-P458. DOI: 10.1016/J.Jalz.2013.05.920  0.296
2015 Vellas B, Bateman R, Blennow K, Frisoni G, Johnson K, Katz R, Langbaum J, Marson D, Sperling R, Wessels A, Salloway S, Doody R, Aisen P. Endpoints for Pre-Dementia AD Trials: A Report from the EU/US/CTAD Task Force. The Journal of Prevention of Alzheimer's Disease. 2: 128-135. PMID 26247004 DOI: 10.14283/jpad.2015.55  0.296
2014 Amariglio RE, Mormino E, Vannini P, Marshall G, Johnson K, Sperling RA, Rentz DM. P2-246: GREATER SUBJECTIVE COGNITIVE CONCERNS CORRESPOND WITH ADVANCING STAGES OF PRECLINICAL AD Alzheimer's & Dementia. 10: P566-P566. DOI: 10.1016/j.jalz.2014.05.923  0.296
2015 Mattsson N, Insel PS, Donohue M, Jagust W, Sperling R, Aisen P, Weiner MW. Predicting Reduction of Cerebrospinal Fluid β-Amyloid 42 in Cognitively Healthy Controls. Jama Neurology. 72: 554-60. PMID 25775167 DOI: 10.1001/Jamaneurol.2014.4530  0.295
2007 Diamond EL, Miller S, Dickerson BC, Atri A, DePeau K, Fenstermacher E, Pihlajamäki M, Celone K, Salisbury S, Gregas M, Rentz D, Sperling RA. Relationship of fMRI activation to clinical trial memory measures in Alzheimer disease. Neurology. 69: 1331-41. PMID 17893294 DOI: 10.1212/01.Wnl.0000277292.37292.69  0.295
2017 Yang H, Yu L, White CC, Sperling RA, De Jager PL, Bennett DA, Schneider JA. [P1-154]: APOE ε4 IS ASSOCIATED WITH HIGHER TDP-43 PROTEINOPATHY BURDEN IN ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P301-P302. DOI: 10.1016/J.Jalz.2017.06.221  0.295
2004 Dickerson BC, Salat DH, Bates JF, Atiya M, Killiany RJ, Greve DN, Dale AM, Stern CE, Blacker D, Albert MS, Sperling RA. Medial temporal lobe function and structure in mild cognitive impairment. Annals of Neurology. 56: 27-35. PMID 15236399 DOI: 10.1002/Ana.20163  0.295
2018 Lee S, Zimmerman ME, Narkhede A, Nasrabady SE, Tosto G, Meier IB, Benzinger TLS, Marcus DS, Fagan AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Sperling RA, et al. White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease. Plos One. 13: e0195838. PMID 29742105 DOI: 10.1371/Journal.Pone.0195838  0.295
2006 Sanchez JS, Sperling RA, Lopera F, Augustinack J, Becker A, Jacobs HI, Jin D, Katz S, Luner E, Moody K, Price JC, Guzman-Velez E, Baena A, Pardilla-Delgado E, Chen K, et al. P2-452: TAU ACCUMULATION IN RHINAL CORTEX IS ASSOCIATED WITH MEMORY PERFORMANCE IN NONDEMENTED YOUNG ADULTS WITH AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P892-P892. DOI: 10.1016/j.jalz.2018.06.1145  0.294
2016 Jack CR, Bennett DA, Blennow K, Carrillo MC, Feldman HH, Frisoni GB, Hampel H, Jagust WJ, Johnson KA, Knopman DS, Petersen RC, Scheltens P, Sperling RA, Dubois B. A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers. Neurology. PMID 27371494 DOI: 10.1212/Wnl.0000000000002923  0.294
2019 Manning LK, Papp KV, Hampton O, Scott MR, Uquillas Fd, Jiang S, Rentz DM, Johnson KA, Sperling RA, Schultz AP. P3-349: ASSOCIATIONS OF REGIONAL CORTICAL THINNING AND LONGITUDINAL COGNITIVE PERFORMANCE IN THE CONTEXT OF AMYLOID IN CLINICALLY NORMAL OLDER ADULTS Alzheimer's & Dementia. 15: P1077-P1077. DOI: 10.1016/j.jalz.2019.06.3381  0.294
2014 Amariglio RE, Mormino E, Vannini P, Marshall G, Johnson KA, Sperling RA, Rentz DM. Greater Subjective Cognitive Concerns Correspond With Advancing Stages Of Preclinical Ad Alzheimers & Dementia. 10: 4. DOI: 10.1016/J.Jalz.2014.04.024  0.294
2019 Sanchez JS, Lopera F, Sperling RA, Becker A, Artola A, Baena A, Jacobs HI, Hanseeuw BJ, Schultz AP, Gatchel JR, Katz S, Mayblyum D, Moody K, Price JC, Bocanegra Y, et al. P4-312: LONGITUDINAL PET MEASURES OF TAU AND AMYLOID ACCUMULATION IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE: FINDINGS FROM THE COLBOS PROJECT Alzheimer's & Dementia. 15: P1411-P1411. DOI: 10.1016/J.Jalz.2019.06.3982  0.293
2017 Hanseeuw BJ, Mormino BC, Becker A, Sepulcre J, Papp KV, Schultz AP, Jacobs HI, Cosio DM, Chhatwal JP, Sperling RA, Johnson K. Longitudinal Tau Accumulation Is Associated With Cognitive Decline In Normal Elderly Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.2556  0.293
2019 Gatchel JR, Amariglio R, Sikkes SAM, Donovan NJ, Rentz DM, Sun C, Donohue MC, Aisen PS, Sperling RA, Marshall GA, Team AS. P1-286: Geriatric Depression Scale (Gds) Item-Level Analysis By Amyloid Pet And Cognition: Findings From The Anti-Amyloid Treatment In Asymptomatic Alzheimer'S Disease (A4) Study Screening Data Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.841  0.293
2016 Winblad B, Amouyel P, Andrieu S, Ballard C, Brayne C, Brodaty H, Cedazo-Minguez A, Dubois B, Edvardsson D, Feldman H, Fratiglioni L, Frisoni GB, Gauthier S, Georges J, Graff C, ... ... Sperling R, et al. Defeating Alzheimer's disease and other dementias: a priority for European science and society. The Lancet. Neurology. 15: 455-532. PMID 26987701 DOI: 10.1016/S1474-4422(16)00062-4  0.292
2008 Dickerson BC, Sperling RA. Functional abnormalities of the medial temporal lobe memory system in mild cognitive impairment and Alzheimer's disease: insights from functional MRI studies. Neuropsychologia. 46: 1624-35. PMID 18206188 DOI: 10.1016/j.neuropsychologia.2007.11.030  0.292
2020 Hampton OL, Mukherjee S, Properzi MJ, Schultz AP, Crane PK, Gibbons LE, Hohman TJ, Maruff PT, Lim YY, Amariglio R, Papp KV, Johnson KA, Rentz D, Sperling RA, Buckley RF. Harmonizing the preclinical Alzheimer cognitive composite for multi‐cohort studies Alzheimer's & Dementia. 16. DOI: 10.1002/alz.047423  0.292
2017 Hanseeuw BJ, Mormino BC, Becker A, Schultz AP, Sepulcre J, Papp KV, Jacobs HI, Cosio DM, Chhatwal JP, Rentz DM, Sperling RA, Johnson K. [P4-228]: LONGITUDINAL TAU ACCUMULATION IS ASSOCIATED WITH COGNITIVE DECLINE IN NORMAL ELDERLY Alzheimer's & Dementia. 13: P1357-P1359. DOI: 10.1016/j.jalz.2017.06.2096  0.291
2019 Ying Lim YY, Sperling RA, Insel P, Maruff P, Johnson KA, Mormino EC. DISTINCT CONTRIBUTIONS OF BASELINE AND LONGITUDINAL AMYLOID PET MEASURES TO MEMORY DECLINE IN COGNITIVELY NORMAL OLDER ADULTS Alzheimer's & Dementia. 15: P179-P180. DOI: 10.1016/j.jalz.2019.06.4379  0.291
2016 Sepulcre J, Grothe MJ, Sabuncu M, Schultz AP, Hanseeuw BJ, Sperling RA, Johnson KA. In Vivo Cortical Distribution Of Tau And Amyloid Deposits In Cognitively Normal Elderly Alzheimers & Dementia. 12: 274. DOI: 10.1016/J.Jalz.2016.06.500  0.291
2018 Amariglio RE, Buckley RF, Mormino EC, Marshall GA, Johnson KA, Rentz DM, Sperling RA. Amyloid-associated increases in longitudinal report of subjective cognitive complaints. Alzheimer's & Dementia (New York, N. Y.). 4: 444-449. PMID 30258973 DOI: 10.1016/j.trci.2018.08.005  0.291
2018 Orlovsky I, Huijbers W, Hanseeuw BJ, Mormino EC, Hedden T, Buckley RF, LaPoint M, Rabin JS, Rentz DM, Johnson KA, Sperling RA, Papp KV. The relationship between recall of recently versus remotely encoded famous faces and amyloidosis in clinically normal older adults. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 121-129. PMID 29780861 DOI: 10.1016/J.Dadm.2017.11.003  0.291
2012 Amariglio RE, Frishe K, Olson LE, Wadsworth LP, Lorius N, Sperling RA, Rentz DM. Validation of the Face Name Associative Memory Exam in cognitively normal older individuals. Journal of Clinical and Experimental Neuropsychology. 34: 580-7. PMID 22765048 DOI: 10.1080/13803395.2012.666230  0.29
2006 Quiroz YT, Sperling RA, Lopera F, Baena A, Alvarez S, Guzman-Velez E, Pardilla-Delgado E, Arboleda-Velasquez J, Gatchel JR, Fuller J, Artola A, Schultz AP, Chen K, Tariot PN, Reiman EM, et al. P4-299: TAU ACCUMULATION IN THE ENTORHINAL CORTEX AND PRECUNEUS IS ASSOCIATED WITH CORTICAL AMYLOID-BETA BURDEN, AGE AND WORSE MEMORY PERFORMANCE IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1567-P1567. DOI: 10.1016/J.Jalz.2018.07.121  0.29
2019 Rentz DM, Papp KV, Sperling RA, Souillard-Mandar W, Penney DL, Davis R, Johnson KA. F3-01-02: CAPTURING COGNITIVE IMPAIRMENT AT THE PRECLINICAL STAGE OF ALZHEIMER'S DISEASE USING DIGITAL TECHNOLOGY Alzheimer's & Dementia. 15: P863-P864. DOI: 10.1016/J.Jalz.2019.06.4597  0.289
2011 Rentz DM, Amariglio RE, Becker JA, Frey M, Olson LE, Frishe K, Carmasin J, Maye JE, Johnson KA, Sperling RA. Face-name associative memory performance is related to amyloid burden in normal elderly. Neuropsychologia. 49: 2776-83. PMID 21689670 DOI: 10.1016/J.Neuropsychologia.2011.06.006  0.289
2016 Mormino EC, Sperling RA, Holmes AJ, Buckner RL, De Jager PL, Smoller JW, Sabuncu MR. Polygenic risk of Alzheimer disease is associated with early- and late-life processes. Neurology. PMID 27385740 DOI: 10.1212/Wnl.0000000000002922  0.289
2020 Sperling RA, Donohue MC, Raman R, Sun CK, Yaari R, Holdridge K, Siemers E, Johnson KA, Aisen PS. Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals. Jama Neurology. PMID 32250387 DOI: 10.1001/Jamaneurol.2020.0387  0.288
2015 Rentz DM, Mormino EC, Amariglio R, Papp KV, Schultz AP, Sperling RA, Johnson KA. IC-P-068: The relationship of cognition, cognitive reserve, and in vivo tau and amyloid burden Alzheimer's & Dementia. 11: P51-P51. DOI: 10.1016/j.jalz.2015.06.089  0.288
2015 Masters CL, Bateman R, Blennow K, Rowe CC, Sperling RA, Cummings JL. Alzheimer's disease. Nature Reviews. Disease Primers. 1: 15056. PMID 27188934 DOI: 10.1038/nrdp.2015.56  0.287
2006 Jacobs HI, Lopera F, Sperling RA, Norton D, Guzman-Velez E, Baena A, Pardilla-Delgado E, Gatchel JR, Chen K, Reiman EM, Johnson KA, Quiroz YT. P2-461: ENTORHINAL TAU PATHOLOGY IS ASSOCIATED WITH WHITE MATTER ABNORMALITIES IN UNCINATE FASCICULUS IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P897-P898. DOI: 10.1016/J.Jalz.2018.06.1154  0.287
2019 Schultz AP, Buckley RF, Hampton OL, Scott MR, Properzi MJ, Peña-Gómez C, Pruzin JJ, Yang HS, Johnson KA, Sperling RA, Chhatwal JP. Longitudinal degradation of the default/salience network axis in symptomatic individuals with elevated amyloid burden. Neuroimage. Clinical. 102052. PMID 31711955 DOI: 10.1016/J.Nicl.2019.102052  0.287
2006 Hanseeuw BJ, Lopera F, Sperling RA, Norton D, Guzman-Velez E, Baena A, Schultz AP, Gatchel JR, Chen K, Reiman EM, Johnson KA, Quiroz YT. IC-P-140: TAU ACCUMULATION AND MEMORY DECLINE ARE MORE CLOSELY RELATED TO STRIATAL THAN CORTICAL AMYLOIDOSIS IN INDIVIDUALS WITH EARLY-ONSET AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P117-P117. DOI: 10.1016/J.Jalz.2018.06.2206  0.287
2014 Huijbers W, Mormino E, Schultz A, Chhatwal J, Boot BP, Amariglio RE, Marshall G, Rentz DM, Johnson KA, Sperling R. IC-P-117: AMYLOID-B DEPOSITION IN MILD COGNITIVE IMPAIRMENT IS ASSOCIATED WITH HIPPOCAMPAL HYPERACTIVATION, ATROPHY, AND CLINICAL PROGRESSION Alzheimer's & Dementia. 10: P65-P66. DOI: 10.1016/j.jalz.2014.05.123  0.287
2019 Marshall GA, Aghjayan SL, Dekhtyar M, Locascio JJ, Jethwani K, Amariglio RE, Czaja SJ, Loewenstein DA, Johnson KA, Sperling RA, Rentz DM. Measuring instrumental activities of daily living in non-demented elderly: a comparison of the new performance-based Harvard Automated Phone Task with other functional assessments. Alzheimer's Research & Therapy. 11: 4. PMID 30630529 DOI: 10.1186/S13195-018-0464-X  0.286
2020 Norton DJ, Parra MA, Sperling RA, Baena A, Guzman-Velez E, Jin DS, Andrea N, Khang J, Schultz A, Rentz DM, Pardilla-Delgado E, Fuller J, Johnson K, Reiman EM, Lopera F, et al. Visual short-term memory relates to tau and amyloid burdens in preclinical autosomal dominant Alzheimer's disease. Alzheimer's Research & Therapy. 12: 99. PMID 32825838 DOI: 10.1186/S13195-020-00660-Z  0.286
2015 Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman RJ, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo MC, Weninger S. CAP-advancing the evaluation of preclinical Alzheimer disease treatments. Nature Reviews. Neurology. PMID 26416539 DOI: 10.1038/Nrneurol.2015.177  0.286
2020 Marshall GA, Sikkes SAM, Amariglio RE, Gatchel JR, Rentz DM, Johnson KA, Langford O, Sun CK, Donohue MC, Raman R, Aisen PS, Sperling RA, Galasko DR. Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12118. PMID 33163609 DOI: 10.1002/dad2.12118  0.286
2019 Vannini P, Uquillas FD, Jacobs HIL, Sepulcre J, Gatchel J, Amariglio RE, Hanseeuw B, Papp KV, Hedden T, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA. Decreased meta-memory is associated with early tauopathy in cognitively unimpaired older adults. Neuroimage. Clinical. 24: 102097. PMID 31795044 DOI: 10.1016/J.Nicl.2019.102097  0.286
2017 Rabin JS, Kilpatrick EP, Buckley RF, Marshall GA, Properzi M, Klein H, Schultz AP, Rao V, Rentz DM, Hedden T, Johnson K, Sperling RA, Chhatwal JP. [P1-256]: BASELINE CARDIOVASCULAR RISK AND AMYLOID BURDEN SYNERGISTICALLY PREDICT LONGITUDINAL COGNITIVE DECLINE IN CLINICALLY NORMAL ELDERLY: FINDINGS FROM THE HARVARD AGING BRAIN STUDY Alzheimer's & Dementia. 13: P347-P347. DOI: 10.1016/J.Jalz.2017.06.272  0.286
2016 Mormino EC, Papp KV, Schultz AP, Hanseeuw BJ, Munro CE, Jaimes SY, Meneide T, Kilpatrick EP, Aghjayan SL, Jonas VH, Kirn D, Jackson JD, Amariglio R, Rentz DM, Sperling RA, et al. O4-01-06: Ab+ Clinically Normal Participants with Elevated Tau Show Greatest Decline in the Preclinical Alzheimer’s Disease Cognitive Composite Alzheimer's & Dementia. 12: P333-P334. DOI: 10.1016/J.Jalz.2016.06.611  0.285
2019 Gatchel JR, Rabin JS, Buckley RF, Locascio JJ, Quiroz YT, Yang HS, Vannini P, Amariglio RE, Rentz DM, Properzi M, Donovan NJ, Blacker D, Johnson KA, Sperling RA, Marshall GA, et al. Longitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults. Jama Network Open. 2: e198964. PMID 31397865 DOI: 10.1001/jamanetworkopen.2019.8964  0.285
2013 Sperling RA, Johnson KA, Doraiswamy PM, Reiman EM, Fleisher AS, Sabbagh MN, Sadowsky CH, Carpenter A, Davis MD, Lu M, Flitter M, Joshi AD, Clark CM, Grundman M, Mintun MA, et al. Amyloid deposition detected with florbetapir F 18 ((18)F-AV-45) is related to lower episodic memory performance in clinically normal older individuals. Neurobiology of Aging. 34: 822-31. PMID 22878163 DOI: 10.1016/j.neurobiolaging.2012.06.014  0.284
2013 Fleisher AS, Chen K, Liu X, Ayutyanont N, Roontiva A, Thiyyagura P, Protas H, Joshi AD, Sabbagh M, Sadowsky CH, Sperling RA, Clark CM, Mintun MA, Pontecorvo MJ, Coleman RE, et al. Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease. Neurobiology of Aging. 34: 1-12. PMID 22633529 DOI: 10.1016/J.Neurobiolaging.2012.04.017  0.284
2012 Chhatwal JP, Sperling RA. Functional MRI of mnemonic networks across the spectrum of normal aging, mild cognitive impairment, and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: S155-67. PMID 22890098 DOI: 10.3233/Jad-2012-120730  0.283
2015 Sperling RA, Amariglio RE, Marshall GA, Rentz DM. Establishing Clinical Relevance in Preclinical Alzheimer's Disease. The Journal of Prevention of Alzheimer's Disease. 2: 85-87. PMID 26247003 DOI: 10.14283/jpad.2015.56  0.283
2016 Rentz DM, Mormino EC, Papp KV, Johnson K, Sperling RA. F1-04-01: Longitudinal Peformance on the Preclinical Alzheimer’s Cognitive Composite (PACC) in Subjects with Biomarker-Defined Preclincal ad Alzheimer's & Dementia. 12: P167-P167. DOI: 10.1016/J.Jalz.2016.06.283  0.282
2021 Rentz DM, Papp KV, Mayblyum DV, Sanchez JS, Klein H, Souillard-Mandar W, Sperling RA, Johnson KA. Association of Digital Clock Drawing with PET Amyloid and Tau Pathology in Normal Older Adults. Neurology. PMID 33589537 DOI: 10.1212/WNL.0000000000011697  0.282
2011 Rentz D, Betensky R, Becker A, England R, Maye J, Gidicsin C, Sperling R, Johnson K. P1-341: Amyloid deposition in non-demented elderly predicts longitudinal cognitive decline Alzheimer's & Dementia. 7: S221-S221. DOI: 10.1016/J.Jalz.2011.05.621  0.282
2012 Schneider JA, Montine TJ, Sperling RA, Bennett DA. Neuropathological basis of Alzheimer's disease and Alzheimer's disease diagnosis Advances in Biological Psychiatry. 28: 49-70. DOI: 10.1159/000335384  0.281
2017 Amariglio R, Buckley RF, Mormino BC, Wang C, Aghjayan SL, Rentz DM, Johnson K, Sperling RA. SUBJECTIVE COGNITIVE DECLINE, LONGITUDINAL COGNITIVE PERFORMANCE, AND IMAGING BIOMARKERS IN PRECLINICAL ALZHEIMER’S DISEASE Alzheimer's & Dementia. 13: P176. DOI: 10.1016/J.Jalz.2017.07.020  0.281
2019 Yang HS, Chhatwal JP, Xu J, White CC, Hanseeuw B, Rabin JS, Papp KV, Buckley RF, Schultz AP, Properzi MJ, Gatchel JR, Amariglio RE, Donovan NJ, Mormino EC, Hedden T, ... ... Sperling RA, et al. An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults. Journal of Alzheimer's Disease : Jad. PMID 30883345 DOI: 10.3233/Jad-180788  0.281
1995 Sandson TA, Sperling RA, Price BH. Alzheimer's disease: An update Comprehensive Therapy. 21: 480-485. PMID 8565434  0.281
2010 Sperling R. Functional MRI Studies in Aging and Early Alzheimer's Disease: Predicting Clinical Decline Imaging the Aging Brain. DOI: 10.1093/acprof:oso/9780195328875.003.0018  0.281
2019 Buckley RF, Mormino EC, Rabin JS, Hohman TJ, Landau S, Hanseeuw BJ, Jacobs HIL, Papp KV, Amariglio RE, Properzi MJ, Schultz AP, Kirn D, Scott MR, Hedden T, Farrell M, ... ... Sperling RA, et al. Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured By Positron Emission Tomography in Clinically Normal Older Adults. Jama Neurology. PMID 30715078 DOI: 10.1001/Jamaneurol.2018.4693  0.281
2020 Amariglio R, Chou HL, Buckley RF, Papp KV, Rentz DM, Johnson KA, Sperling RA. The dynamic interplay between longitudinal subjective and objective cognitive decline along the early AD spectrum in the Harvard Aging Brain Study Alzheimer's & Dementia. 16. DOI: 10.1002/alz.040260  0.28
2019 Manning LK, Papp KV, Hampton O, Scott MR, Uquillas Fd, Jiang S, Rentz DM, Johnson KA, Sperling RA, Schultz AP. IC-P-089: ASSOCIATIONS OF REGIONAL CORTICAL THINNING AND LONGITUDINAL COGNITIVE PERFORMANCE IN THE CONTEXT OF AMYLOID IN CLINICALLY NORMAL OLDER ADULTS Alzheimer's & Dementia. 15: P79-P80. DOI: 10.1016/j.jalz.2019.06.4932  0.28
2009 Hedden T, Van Dijk KR, Becker JA, Mehta A, Sperling RA, Johnson KA, Buckner RL. Disruption of functional connectivity in clinically normal older adults harboring amyloid burden. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12686-94. PMID 19812343 DOI: 10.1523/JNEUROSCI.3189-09.2009  0.28
2018 Sepulcre J, Grothe MJ, d'Oleire Uquillas F, Ortiz-Terán L, Diez I, Yang HS, Jacobs HIL, Hanseeuw BJ, Li Q, El-Fakhri G, Sperling RA, Johnson KA. Neurogenetic contributions to amyloid beta and tau spreading in the human cortex. Nature Medicine. PMID 30374196 DOI: 10.1038/S41591-018-0206-4  0.28
2016 Munro CE, Donovan NJ, Amariglio R, Papp KV, Marshall GA, Rentz DM, Pascual-Leone A, Sperling RA, Vannini P. The Impact Of Anosognosia And Anosodiaphoria On The Prediction Of Progression From Mild Cognitive Impairment To Alzheimer’S Disease Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.642  0.279
2015 Sepulcre J, Schultz AP, Becker A, Sperling RA, Johnson KA. O5-01-01: Tau and amyloid deposits relate to distinctive cortical atrophy patterns in cognitively normal elderly Alzheimer's & Dementia. 11: P311-P312. DOI: 10.1016/j.jalz.2015.07.445  0.279
2016 Quiroz YT, Sperling RA, Baena A, Arboleda-Velasquez J, Schultz AP, Cosio DM, LaPoint MR, Judge K, Jaimes SY, Norton DJ, Reiman EM, Lopera F, Johnson K. IC-P-198: TAU and Amyloid PET Imaging in a Colombian Kindred with Autosomal-Dominant Alzheimer's Disease Alzheimer's & Dementia. 12: P143-P144. DOI: 10.1016/J.Jalz.2016.06.229  0.279
2006 Sanchez JS, Sperling RA, Lopera F, Augustinack J, Becker A, Jacobs HI, Jin D, Katz S, Luner E, Moody K, Price JC, Guzman-Velez E, Baena A, Pardilla-Delgado E, Chen K, et al. IC-P-215: TAU ACCUMULATION IN RHINAL CORTEX IS ASSOCIATED WITH MEMORY PERFORMANCE IN NON-DEMENTED YOUNG ADULTS WITH AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P176-P177. DOI: 10.1016/J.Jalz.2018.06.2282  0.278
2020 Langford O, Raman R, Sperling RA, Cummings J, Sun CK, Jimenez-Maggiora G, Aisen PS, Donohue MC. Predicting Amyloid Burden to Accelerate Recruitment of Secondary Prevention Clinical Trials. The Journal of Prevention of Alzheimer's Disease. 7: 213-218. PMID 32920622 DOI: 10.14283/jpad.2020.44  0.277
2017 Sepulcre J, Sabuncu MR, Li Q, El Fakhri G, Sperling R, Johnson KA. Tau and Aβ proteins distinctively associate to functional network changes in the aging brain. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28366797 DOI: 10.1016/J.Jalz.2017.02.011  0.277
2019 Biddle KD, Uquillas Fd, Zide B, Kirn D, Jacobs HI, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. P3-305: SYNERGISTIC ADVERSE EFFECTS OF WIDOWHOOD AND AMYLOID-β ON COGNITIVE DECLINE IN COGNITIVELY NORMAL OLDER ADULTS Alzheimer's & Dementia. 15: P1054-P1054. DOI: 10.1016/j.jalz.2019.06.3337  0.276
2020 Buckley RF, Scott MR, Jacobs HI, Schultz AP, Properzi MJ, Amarglio RE, Hohman TJ, Mayblyum DV, Rubinstein ZB, Manning L, Hanseeuw BJ, Mormino EC, Rentz DM, Johnson KA, Sperling RA. Sex mediates relationships between regional tau pathology and cognitive decline. Annals of Neurology. PMID 32799367 DOI: 10.1002/Ana.25878  0.276
2011 Sperling R. Potential of functional MRI as a biomarker in early Alzheimer's disease. Neurobiology of Aging. 32: S37-43. PMID 22078171 DOI: 10.1016/J.Neurobiolaging.2011.09.009  0.276
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Sperling RA, et al. Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0152082. PMID 27010959 DOI: 10.1371/Journal.Pone.0152082  0.276
2016 Papp KV, Mormino EC, Amariglio R, Schultz AP, Quiroz YT, Jaimes SY, Aghjayan SL, Munro CE, Kilpatrick EP, Johnson K, Sperling RA, Rentz DM. P3-309: Profiles of Cognitive Decline Associated with Biomarker-Defined Preclinical Stages of Alzheimer’s Disease Alzheimer's & Dementia. 12: P960-P961. DOI: 10.1016/J.Jalz.2016.06.1973  0.276
2003 Monsonego A, Zota V, Karni A, Krieger JI, Bar-Or A, Bitan G, Budson AE, Sperling R, Selkoe DJ, Weiner HL. Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease. The Journal of Clinical Investigation. 112: 415-22. PMID 12897209 DOI: 10.1172/Jci18104  0.275
2020 Walter S, Clanton TB, Langford OG, Rafii MS, Shaffer EJ, Grill JD, Jimenez-Maggiora GA, Sperling RA, Cummings JL, Aisen PS. Recruitment into the Alzheimer Prevention Trials (APT) Webstudy for a Trial-Ready Cohort for Preclinical and Prodromal Alzheimer's Disease (TRC-PAD). The Journal of Prevention of Alzheimer's Disease. 7: 219-225. PMID 32920623 DOI: 10.14283/jpad.2020.46  0.275
2010 Vitolo OV, Sperling RA. Functional MRI Studies in Ageing and Early Alzheimer's Disease Principles and Practice of Geriatric Psychiatry: Third Edition. 437-445. DOI: 10.1002/9780470669600.ch70  0.275
2009 Becker JA, Rentz DM, Carmasin J, Hedden T, Hamdi I, Buckner RL, Sperling RA, Johnson KA. Amyloid deposition and brain volume across the continuum of aging and Alzheimer's Disease Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.05.426  0.274
2017 Buckley RF, Hanseeuw BJ, Schultz AP, Vannini P, Jackson JD, Papp KV, Mormino BC, Rentz DM, Sperling RA, Johnson K, Amariglio R. Severity Of Subjective Cognitive Decline Aligns With Regional Amyloid Severity: Findings From The Harvard Aging Brain Study Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.07.200  0.274
2019 Buckley RF, Mormino EC, Chhatwal J, Schultz AP, Rabin JS, Rentz DM, Acar D, Properzi MJ, Dumurgier J, Jacobs H, Gomez-Isla T, Johnson KA, Sperling RA, Hanseeuw BJ. Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid. Neurobiology of Aging. 78: 178-185. PMID 30947113 DOI: 10.1016/J.Neurobiolaging.2019.02.019  0.273
2017 Kinnunen KM, Cash DM, Poole T, Frost C, Benzinger TLS, Ahsan RL, Leung KK, Cardoso MJ, Modat M, Malone IB, Morris JC, Bateman RJ, Marcus DS, Goate A, Salloway S, ... ... Sperling RA, et al. Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28738187 DOI: 10.1016/J.Jalz.2017.06.2268  0.273
2015 Quiroz YT, Amariglio R, Aguirre-Acevedo DC, Opoka S, Pulsifer B, Jaimes SY, Castrillon G, Tirado V, Munoz C, Sperling RA, Lopera F. Associations between subjective memory complaints and hippocampal volume in preclinical early-onset Alzheimer's disease Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.972  0.273
2016 Gatchel JR, Donovan NJ, Locascio JJ, Becker A, Rentz DM, Sperling RA, Johnson K, Marshall GA. Regional Fluorodeoxyglucose Hypometabolism Is Associated With Greater Apathy Over Time In Early Alzheimer'S Disease Alzheimers & Dementia. 12: 1111. DOI: 10.1016/J.Jalz.2016.06.083  0.272
2016 Quiroz YT, Sperling RA, Baena A, Arboleda-Velasquez J, Schultz AP, Cosio DM, LaPoint MR, Judge K, Jaimes SY, Norton DJ, Reiman EM, Lopera F, Johnson K. O4-01-02: Tau and Amyloid Pet Imaging in a Colombian Kindred with Autosomal-Dominant Alzheimer's Disease Alzheimer's & Dementia. 12: P330-P330. DOI: 10.1016/j.jalz.2016.06.607  0.272
2020 Aisen PS, Cummings J, Doody R, Kramer L, Salloway S, Selkoe DJ, Sims J, Sperling RA, Vellas B. The Future of Anti-Amyloid Trials. The Journal of Prevention of Alzheimer's Disease. 7: 146-151. PMID 32463066 DOI: 10.14283/jpad.2020.24  0.272
2011 Amariglio RE, Townsend MK, Grodstein F, Sperling RA, Rentz DM. Specific subjective memory complaints in older persons may indicate poor cognitive function. Journal of the American Geriatrics Society. 59: 1612-7. PMID 21919893 DOI: 10.1111/j.1532-5415.2011.03543.x  0.272
2016 Gatchel JR, Donovan NJ, Locascio JJ, Becker A, Rentz DM, Sperling RA, Johnson K, Marshall GA. P4-217: Regional Fluorodeoxyglucose Hypometabolism is Associated With Greater Apathy Over Time in Early Alzheimer's Disease Alzheimer's & Dementia. 12: P1111-P1111. DOI: 10.1016/j.jalz.2016.06.2309  0.272
2012 Bateman R, Benzinger T, Cairns N, Fagan A, Goate A, Marcus D, Storandt M, Xiong C, Buckles V, Holtzman D, Moulder K, Oliver A, Santacruz A, Fox N, Ghetti B, ... ... Sperling R, et al. Presymptomatic Alzheimer's disease in the Dominantly Inherited Alzheimer's Network (DIAN) Alzheimers & Dementia. 8: 4. DOI: 10.1016/J.Jalz.2012.05.015  0.271
2020 Rodriguez‐Vieitez E, Montal V, Sepulcre J, Lois C, Hanseeuw B, Vilaplana E, Schultz AP, Properzi MJ, Scott MR, Fortea J, Johnson KA, Sperling RA, Vannini P. The relationship between cortical microstructural changes and in vivo amyloid‐β and tau in aging and preclinical Alzheimer's disease Alzheimer's & Dementia. 16. DOI: 10.1002/alz.041626  0.271
2012 Porsteinsson A, Sperling R, Salloway S, Crans G, Hernandez C, Abushakra S. Responders to ELND005 (Scyllo-Inositol) Demonstrate Clinical and Biomarker Characteristics Consistent with Mild Alzheimer's Disease (AD): Data from a 78-Week Phase 2 Study in Mild to Moderate (M/M) AD (P04.194) Neurology. 78: P04.194-P04.194. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P04.194  0.271
2018 Rabin JS, Perea RD, Buckley RF, Neal TE, Buckner RL, Johnson KA, Sperling RA, Hedden T. Global White Matter Diffusion Characteristics Predict Longitudinal Cognitive Change Independently of Amyloid Status in Clinically Normal Older Adults. Cerebral Cortex (New York, N.Y. : 1991). PMID 29425267 DOI: 10.1093/cercor/bhy031  0.271
2018 Chen Z, Mengel D, Keshavan A, Rissman RA, Billinton A, Perkinton M, Percival-Alwyn J, Schultz A, Properzi M, Johnson K, Selkoe DJ, Sperling RA, Patel P, Zetterberg H, Galasko D, et al. Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30419228 DOI: 10.1016/J.Jalz.2018.09.010  0.27
2005 Dickerson BC, Salat DH, Greve DN, Albert MS, Blacker D, Sperling RA. [P-095]: An fMRI investigation of memory-related medial temporal lobe activation in mild cognitive impairment prior to dementia Alzheimer's & Dementia. 1: S38-S38. DOI: 10.1016/J.Jalz.2005.06.169  0.27
2006 Rabin JS, Buckley RF, Chhatwal JP, Hedden T, Schultz AP, Gatchel JR, Yang H, Rentz DM, Johnson KA, Sperling RA, Amariglio R. F4-08-02: AMYLOID BURDEN AND VASCULAR RISK ARE INDEPENDENTLY ASSOCIATED WITH SUBJECTIVE COGNITIVE DECLINE IN CLINICALLY NORMAL OLDER ADULTS Alzheimer's & Dementia. 14: P1394-P1395. DOI: 10.1016/J.Jalz.2018.06.2893  0.27
2014 Rentz DM, Papp KV, Mormino EC, Amariglio RE, Becker JA, Schultz AP, Johnson KA, Sperling RA. IC-P-087: DETECTING COGNITIVE PROFILES IN THE BIOMARKER STAGES OF PRECLINICAL AD Alzheimer's & Dementia. 10: P49-P50. DOI: 10.1016/j.jalz.2014.05.092  0.269
2019 Jutten RJ, Sikkes SAM, Amariglio R, Buckley RF, Properzi MJ, Marshall GA, Rentz DM, Johnson KA, Flier WMvd, Scheltens P, Sperling RA, Papp KV. F2-03-02: Optimizing Cognitive Outcomes For Biomarker Positive Individuals At Different Clinical Stages Of Alzheimer'S Disease According To The Nia-Aa Research Framework Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4425  0.269
2021 Yang HS, Zhang C, Carlyle BC, Zhen SY, Trombetta BA, Schultz AP, Pruzin JJ, Fitzpatrick CD, Yau WW, Kirn DR, Rentz DM, Arnold SE, Johnson KA, Sperling RA, Chhatwal JP, et al. Plasma IL-12/IFN-γ axis predicts cognitive trajectories in cognitively unimpaired older adults. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34160128 DOI: 10.1002/alz.12399  0.269
2015 Toledo JB, Zetterberg H, Van Harten AC, Glodzik L, Martinez-Lage P, Bocchio-Chiavetto L, Rami L, Hansson O, Sperling R, Engelborghs S, Osorio RS, Vanderstichele H, Vandijck M, Hampel H, Teipl S, et al. Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects Brain. 138: 2701-2715. DOI: 10.1093/brain/awv199  0.269
2015 Harkins K, Sankar P, Sperling R, Grill JD, Green RC, Johnson KA, Healy M, Karlawish J. Development of a process to disclose amyloid imaging results to cognitively normal older adult research participants. Alzheimer's Research & Therapy. 7: 26. PMID 25969699 DOI: 10.1186/S13195-015-0112-7  0.269
2006 Rentz DM, Sardinha LM, Huh TJ, Searl MM, Daffner KR, Sperling RA. IQ-based norms for highly intelligent adults. The Clinical Neuropsychologist. 20: 637-48. PMID 16980251 DOI: 10.1080/13854040500477498  0.268
2007 Glanz BI, Holland CM, Gauthier SA, Amunwa EL, Liptak Z, Houtchens MK, Sperling RA, Khoury SJ, Guttmann CR, Weiner HL. Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 13: 1004-10. PMID 17623735 DOI: 10.1177/1352458507077943  0.268
2004 Dickerson BC, Salat DH, Bates JF, Atiya M, Killiany RJ, Greve DN, Dale AM, Stern CE, Blacker D, Albert MS, Sperling RA. P2-165 Functional and structural MRI in questionable AD: relationships to clinical impairment and future decline Neurobiology of Aging. 25: S272-S273. DOI: 10.1016/S0197-4580(04)80912-6  0.267
2008 Sperling R, O'Brien J, O'Keefe K, DeLuca A, LaViolette P, Pihlajamaki M, Johnson K, Blacker D, Dickerson B. IC-P2-139: Longitudinal fMRI demonstrates loss of hippocampal function associated with clinical decline in non-demented older subjects Alzheimer's & Dementia. 4: T62-T62. DOI: 10.1016/J.Jalz.2008.05.2593  0.267
2013 Vellas B, Carrillo MC, Sampaio C, Brashear HR, Siemers E, Hampel H, Schneider LS, Weiner M, Doody R, Khachaturian Z, Cedarbaum J, Grundman M, Broich K, Giacobini E, Dubois B, ... Sperling R, et al. Designing drug trials for Alzheimer's disease: what we have learned from the release of the phase III antibody trials: a report from the EU/US/CTAD Task Force. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 438-44. PMID 23809364 DOI: 10.1016/J.Jalz.2013.03.007  0.266
2013 Johnson KA, Sperling RA, Sepulcre J. Functional connectivity in Alzheimer's disease: measurement and meaning. Biological Psychiatry. 74: 318-9. PMID 23932342 DOI: 10.1016/j.biopsych.2013.07.010  0.266
2012 Marshall G, Lorius N, Gidicsin C, Maye J, Becker JA, Amariglio R, Rentz D, Sperling R, Johnson K. Instrumental Activities of Daily Living Impairment Is Associated with Temporal and Parietal Hypometabolism in Mild Cognitive Impairment (P04.214) Neurology. 78: P04.214-P04.214. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P04.214  0.264
2006 Hedden T, Buckley RF, Downey NR, Hohman TJ, Johnson KA, Papp KV, Rentz DM, Sperling RA. IC-P-159: BRAIN RESILIENCE PROTECTS AGAINST COGNITIVE DECLINE ASSOCIATED WITH ELEVATED AMYLOID BURDEN Alzheimer's & Dementia. 14: P134-P135. DOI: 10.1016/J.Jalz.2018.06.2226  0.264
2014 Rentz DM, Papp KV, Mormino EV, Amariglio RV, Becker JA, Schultz AP, Johnson KA, Sperling RA. O4-12-04: DETECTING COGNITIVE PROFILES IN THE BIOMARKER STAGES OF PRECLINICAL AD Alzheimer's & Dementia. 10: P276-P276. DOI: 10.1016/j.jalz.2014.04.454  0.264
2020 Chhatwal JP, Schultz AP, Dang Y, Ostaszewski B, Liu L, Yang H, Johnson KA, Sperling RA, Selkoe DJ. Plasma levels of an N‐terminal tau fragment are highly associated with future cognitive decline and neurodegeneration in clinically normal elderly Alzheimer's & Dementia. 16. DOI: 10.1002/alz.045261  0.263
2017 Marshall GA, Aghjayan SL, Dekhtyar M, Locascio JJ, Jethwani K, Amariglio RE, Johnson KA, Sperling RA, Rentz DM. Activities of daily living measured by the Harvard Automated Phone Task track with cognitive decline over time in non-demented elderly. The Journal of Prevention of Alzheimer's Disease. 4: 81-86. PMID 29124043 DOI: 10.14283/jpad.2017.10  0.262
2015 Schultz AP, Mormino EC, Chhatwal JP, LaPoint M, Dagley AS, Sperling RA, Johnson KA. IC-P-156: Baseline amyloid PET imaging, longitudinal amyloid accumulation, and Tau PET imaging in preclinical Alzheimer's disease Alzheimer's & Dementia. 11: P105-P105. DOI: 10.1016/J.Jalz.2015.06.179  0.262
2005 Klunk B, Price J, Mathis C, Reiman E, Jack C, Fagan T, Kinoshita J, Albensi B, Tuller B, Kung HF, Andrews J, Johnson K, Pawlak MA, Fox N, Sperling R, et al. Alzheimer research forum live discussion: Imaging in Alzheimer's disease: The current state of affairs Journal of Alzheimer's Disease. 8: 387-392. PMID 16646142  0.262
2016 Weninger S, Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman R, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo M. F4-03-01: Collaboration for Alzheimer's Prevention (CAP): Advancing the Evaluation of Preclinical Alzheimer's Disease Treatments Alzheimer's & Dementia. 12: P325-P326. DOI: 10.1016/J.Jalz.2016.06.596  0.262
2011 Sperling RA, Jack CR, Aisen PS. Testing the right target and right drug at the right stage. Science Translational Medicine. 3: 111cm33. PMID 22133718 DOI: 10.1126/Scitranslmed.3002609  0.261
2014 McLaren DG, Sperling RA, Atri A. Flexible modulation of network connectivity related to cognition in Alzheimer's disease. Neuroimage. 100: 544-57. PMID 24852459 DOI: 10.1016/J.Neuroimage.2014.05.032  0.261
2020 Rabin JS, Neal TE, Nierle HE, Sikkes SAM, Buckley RF, Amariglio RE, Papp KV, Rentz DM, Schultz AP, Johnson KA, Sperling RA, Hedden T. Multiple markers contribute to risk of progression from normal to mild cognitive impairment. Neuroimage. Clinical. 28: 102400. PMID 32919366 DOI: 10.1016/J.Nicl.2020.102400  0.261
2017 Johnson K, Cosio DM, Becker A, Schultz AP, Lee C, Andrea N, Hanseeuw BJ, Sperling RA. [P1-398]: TAU ACCUMULATION IS DETECTABLE AND CORRELATED TO AMYLOID BURDEN IN NORMAL AND IMPAIRED OLDER INDIVIDUALS USING SERIAL PET Alzheimer's & Dementia. 13: P423-P424. DOI: 10.1016/J.Jalz.2017.06.414  0.261
2016 LaPoint MR, Chhatwal JP, Sepulcre J, Cosio DM, Johnson K, Sperling RA, Schultz AP. P3-275: Increased TAU PET Signal Associated with Longitudinal Mr Atrophy in Cognitively Normal Older Adults Alzheimer's & Dementia. 12: P940-P941. DOI: 10.1016/j.jalz.2016.06.1938  0.261
2014 Growdon ME, Schultz A, Dagley A, Amariglio R, Hedden T, Rentz DM, Johnson K, Sperling R, Albers MW, Marshall G. P1-301: OLFACTORY IDENTIFICATION AND ALZHEIMER'S DISEASE BIOMARKERS IN CLINICALLY NORMAL ELDERLY Alzheimer's & Dementia. 10: P422-P422. DOI: 10.1016/j.jalz.2014.05.542  0.26
2015 Quiroz YT, Protas H, Chen K, Roontiva A, Thiyyagura P, Fagan AM, Shah A, Gutierrez M, Londono M, Giraldo M, Munoz C, Tirado V, Velilla L, Garcia G, Jaimes SY, ... ... Sperling RA, et al. Relationships between baseline biomarkers and subsequent cognitive decline in cognitively unimpaired PSEN1 E280A mutation carriers from the colombian kindred with autosomal dominant Alzheimer’s disease Alzheimers & Dementia. 11: 888. DOI: 10.1016/J.Jalz.2015.08.098  0.26
2017 Guzman-Velez E, Castrillon G, Chen K, Norton D, Baena A, Acosta-Uribe J, Cuastumal A, Lopera F, Sperling RA, Reiman EM, Johnson K, Quiroz YT. [P1-434]: RELATIONSHIPS BETWEEN MEMORY FUNCTION, TAU PATHOLOGY AND FUNCTIONAL CONNECTIVITY IN THE DEFAULT MODE NETWORK IN AUTOSOMAL-DOMINANT ALZHEIMER's DISEASE: A PRELIMINARY REPORT Alzheimer's & Dementia. 13: P448-P448. DOI: 10.1016/j.jalz.2017.06.450  0.26
2017 Guzman-Velez E, Castrillon G, Chen K, Norton D, Baena A, Acosta-Uribe J, Cuastumal A, Lopera F, Sperling RA, Reiman EM, Johnson K, Quiroz YT. [P1-030]: RELATIONSHIPS BETWEEN MEMORY FUNCTION, TAU PATHOLOGY AND FUNCTIONAL CONNECTIVITY IN THE DEFAULT MODE NETWORK IN AUTOSOMAL-DOMINANT ALZHEIMER's DISEASE: A PRELIMINARY REPORT Alzheimer's & Dementia. 13: P245-P245. DOI: 10.1016/J.Jalz.2017.06.097  0.26
2006 Johnson KA, Pollen D, Rentz D, Moran E, Becker JA, Moonis M, Swearer J, Hyman B, Selkoe D, Sperling R, DeKosky S, Matthis C, Klunk W, Fischman A. P2-268: Amyloid deposition in presymptomatic familial Alzheimer's disease Alzheimer's & Dementia. 2: S317-S317. DOI: 10.1016/J.Jalz.2006.05.1107  0.26
2006 Papp KV, Mormino BC, Grober E, Quiroz YT, Schultz AP, Sperling RA, Johnson KA, Rentz DM. IC-P-147: QUANTIFYING STAGES OF SUBTLE MEMORY IMPAIRMENT IN PRECLINICAL ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P125-P126. DOI: 10.1016/j.jalz.2018.06.2213  0.258
2014 Hedden T, Schultz AP, Rieckmann A, Mormino EC, Johnson KA, Sperling RA, Buckner RL. Multiple Brain Markers are Linked to Age-Related Variation in Cognition. Cerebral Cortex (New York, N.Y. : 1991). PMID 25316342 DOI: 10.1093/cercor/bhu238  0.258
2003 Sperling RA, Bates JF, Chua EF, Cocchiarella AJ, Rentz DM, Rosen BR, Schacter DL, Albert MS. fMRI studies of associative encoding in young and elderly controls and mild Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 74: 44-50. PMID 12486265 DOI: 10.1136/Jnnp.74.1.44  0.258
2009 Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, Andrews-Hanna JR, Sperling RA, Johnson KA. Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1860-73. PMID 19211893 DOI: 10.1523/Jneurosci.5062-08.2009  0.257
2009 Rentz DM, Locascio JJ, Becker JA, Buckner RL, Frey MT, Carmasin J, Hedden T, Sperling RA, Johnson KA. O3-03-07: Cognitive reserve modifies the relationship of neuropsychological performance and amyloid deposition in normal elderly subjects Alzheimer's & Dementia. 5: P131-P132. DOI: 10.1016/j.jalz.2009.05.445  0.257
2020 Amariglio RE, Buckley RF, Rabin JS, Papp KV, Quiroz YT, Mormino EC, Sparks KP, Johnson KA, Rentz DM, Sperling RA. Examining Cognitive Decline Across Black and White Participants in the Harvard Aging Brain Study. Journal of Alzheimer's Disease : Jad. PMID 32417775 DOI: 10.3233/JAD-191291  0.256
2011 Jack CR, Barkhof F, Bernstein MA, Cantillon M, Cole PE, Decarli C, Dubois B, Duchesne S, Fox NC, Frisoni GB, Hampel H, Hill DL, Johnson K, Mangin JF, Scheltens P, ... ... Sperling R, et al. Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 474-485.e4. PMID 21784356 DOI: 10.1016/J.Jalz.2011.04.007  0.256
2017 Reiman EM, Kuang X, Luo J, Chen Y, Thiyyagura P, Bauer R, Lee W, Protas H, Goradia DD, Aisen PS, Johnson K, Langbaum JB, Sperling RA, Tariot P, Jagust WJ, et al. SAMPLE SIZES FOR 24-MONTH ALZHEIMER’S PREVENTION TRIALS USING BIOMARKER ENDPOINTS IN COGNITIVELY UNIMPAIRED AMYLOID-POSITIVE ADULTS Alzheimer's & Dementia. 13: P1453-P1454. DOI: 10.1016/j.jalz.2017.07.509  0.256
2020 Properzi MJ, Buckley RF, Papp KV, Farrell ME, Jacobs HI, Hanseeuw BJ, Rabin JS, Chhatwal JP, Rentz DM, Johnson KA, Sperling RA, Schultz AP. Estimating an individual's placement on a theoretical continuum using longitudinal cognitive trajectories: Relationships with longitudinal amyloid and Tau‐PET Alzheimer's & Dementia. 16. DOI: 10.1002/alz.043566  0.256
2020 Dubbelman MA, Jutten RJ, Farias ST, Amariglio R, Buckley RF, Visser PJ, Rentz DM, Johnson KA, Properzi MJ, Schultz AP, Donovan N, Gatchel JR, Teunissen CE, Van Berckel BN, van Der Flier W, ... Sperling RA, et al. Trajectories of decline in cognitively complex everyday activities across the Alzheimer’s disease continuum Alzheimer's & Dementia. 16. DOI: 10.1002/alz.044787  0.255
2009 Salloway S, Sperling R, Gilman S, Fox NC, Blennow K, Raskind M, Sabbagh M, Honig LS, Doody R, van Dyck CH, Mulnard R, Barakos J, Gregg KM, Liu E, Lieberburg I, et al. A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology. 73: 2061-70. PMID 19923550 DOI: 10.1212/Wnl.0B013E3181C67808  0.255
2013 Ward AM, McLaren DG, Schultz AP, Chhatwal J, Boot BP, Hedden T, Sperling RA. Daytime sleepiness is associated with decreased default mode network connectivity in both young and cognitively intact elderly subjects. Sleep. 36: 1609-15. PMID 24179292 DOI: 10.5665/Sleep.3108  0.255
2019 Rabin JS, Klein H, Kirn D, Schultz AP, Yang H, Hampton O, Jiang S, Buckley RF, Viswanathan A, Hedden T, Pruzin JJ, Yau W, Guzman-Velez E, Quiroz YT, Properzi MJ, ... ... Sperling RA, et al. O3-09-01: PROTECTIVE EFFECT OF PHYSICAL ACTIVITY ON LONGITUDINAL COGNITIVE DECLINE AND NEURODEGENERATION IN CLINICALLY NORMAL OLDER ADULTS WITH ELEVATED β-AMYLOID BURDEN Alzheimer's & Dementia. 15: P903-P904. DOI: 10.1016/J.Jalz.2019.06.4672  0.255
2015 Schultz AP, Mormino EC, Chhatwal JP, LaPoint M, Dagley AS, Sperling RA, Johnson KA. O1-06-05: Baseline amyloid PET imaging, longitudinal amyloid accumulation, and Tau PET imaging in preclinical Alzheimer's disease Alzheimer's & Dementia. 11: P139-P139. DOI: 10.1016/j.jalz.2015.07.061  0.255
2015 Rabin LA, Smart CM, Crane PK, Amariglio RE, Berman LM, Boada M, Buckley RF, Chételat G, Dubois B, Ellis KA, Gifford KA, Jefferson AL, Jessen F, Katz MJ, Lipton RB, ... ... Sperling RA, et al. Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures used Across 19 International Research Studies. Journal of Alzheimer's Disease : Jad. PMID 26402085 DOI: 10.3233/Jad-150154  0.255
2012 Johnson KA, Fox NC, Sperling RA, Klunk WE. Brain imaging in Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 2: a006213. PMID 22474610 DOI: 10.1101/Cshperspect.A006213  0.255
2013 Vannini P, Wigman S, Ward A, Amariglio R, Marshall G, Schultz A, Dijk Kv, Huijbers W, Rentz D, Johnson K, Sperling R. Decreased resting state functional connectivity at baseline predicts subjective memory complaints after 1 year in cognitively normal individuals and individuals with mild cognitive impairment Alzheimers & Dementia. 9: 110. DOI: 10.1016/J.Jalz.2013.05.195  0.255
2013 Mills SM, Mallmann J, Santacruz AM, Fuqua A, Carril M, Aisen PS, Althage MC, Belyew S, Benzinger TL, Brooks WS, Buckles VD, Cairns NJ, Clifford D, Danek A, Fagan AM, ... ... Sperling RA, et al. Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial. Revue Neurologique. 169: 737-43. PMID 24016464 DOI: 10.1016/J.Neurol.2013.07.017  0.254
2013 Chhatwal JP, Schultz AP, Johnson K, Benzinger TL, Jack C, Ances BM, Sullivan CA, Salloway SP, Ringman JM, Koeppe RA, Marcus DS, Thompson P, Saykin AJ, Correia S, Schofield PR, ... ... Sperling RA, et al. Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology. 81: 736-44. PMID 23884042 DOI: 10.1212/Wnl.0B013E3182A1Aafe  0.254
2016 LaPoint MR, Chhatwal JP, Sepulcre J, Cosio DM, Johnson K, Sperling RA, Schultz AP. IC-P-190: Increased TAU PET Signal Associated with Longitudinal Mr Atrophy in Cognitively Normal Older Adults Alzheimer's & Dementia. 12: P137-P138. DOI: 10.1016/J.Jalz.2016.06.221  0.253
2016 Maye JE, Betensky RA, Gidicsin CM, Locascio J, Becker JA, Pepin L, Carmasin J, Rentz DM, Marshall GA, Blacker D, Sperling RA, Johnson KA. Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring. Neurobiology of Aging. 40: 61-7. PMID 26973104 DOI: 10.1016/J.Neurobiolaging.2015.12.013  0.253
2013 Hochstetler H, Doraiswamy PM, Sperling RA, Johnson KA, Reiman E, Sabbagh MN, Sadowsky CH, Joshi AD, Lu M, Mintun MA, Pontecorvo MJ, Skovronsky DM. Relationship of Florbetapir F18 PET Amyloid Plaque Neuroimaging with Future Cognitive Decline over 36 Months The American Journal of Geriatric Psychiatry. 21: S136. DOI: 10.1016/j.jagp.2012.12.180  0.253
2006 Biddle KD, Uquillas Fd, Zide B, Kirn D, Johnson KA, Rentz DM, Sperling RA, Donovan NJ. O2-08-06: AMYLOID-β, COGNITION AND SOCIAL ACTIVITY IN COGNITIVELY NORMAL OLDER ADULTS Alzheimer's & Dementia. 14: P640-P640. DOI: 10.1016/j.jalz.2018.06.2686  0.252
2013 Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, ... ... Sperling RA, et al. The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 81: 1425-33. PMID 24049139 DOI: 10.1212/Wnl.0B013E3182A841C6  0.252
2017 Vannini P, Hanseeuw B, Munro CE, Amariglio RE, Marshall GA, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA. Hippocampal hypometabolism in older adults with memory complaints and increased amyloid burden. Neurology. PMID 28381517 DOI: 10.1212/WNL.0000000000003889  0.252
2017 Papp KV, Mormino BC, Huijbers W, Dickerson BC, Orlovsky I, Schultz AP, Sperling RA, Rentz DM, Johnson K. SEMANTIC MEMORY AND PET AMYLOID AND TAU DEPOSITION IN PRECLINICAL AND PRODROMAL ALZHEIMER’S DISEASE Alzheimer's & Dementia. 13: P911-P912. DOI: 10.1016/J.Jalz.2017.07.333  0.252
2015 Perry D, Sperling R, Katz R, Berry D, Dilts D, Hanna D, Salloway S, Trojanowski JQ, Bountra C, Krams M, Luthman J, Potkin S, Gribkoff V, Temple R, Wang Y, et al. Building a roadmap for developing combination therapies for Alzheimer's disease. Expert Review of Neurotherapeutics. 15: 327-33. PMID 25708309 DOI: 10.1586/14737175.2015.996551  0.251
2018 Donovan NJ, Locascio JJ, Marshall GA, Gatchel J, Hanseeuw BJ, Rentz DM, Johnson KA, Sperling RA. Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults. The American Journal of Psychiatry. appiajp201717040442. PMID 29325447 DOI: 10.1176/Appi.Ajp.2017.17040442  0.251
2012 Mckhann GM, Albert MS, Sperling RA. Changing diagnostic concepts of Alzheimer's disease Advances in Biological Psychiatry. 28: 115-121. DOI: 10.1159/000335402  0.251
2012 Villemagne VL, Klunk WE, Mathis CA, Rowe CC, Brooks DJ, Hyman BT, Ikonomovic MD, Ishii K, Jack CR, Jagust WJ, Johnson KA, Koeppe RA, Lowe VJ, Masters CL, Montine TJ, ... ... Sperling RA, et al. Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. 39: 209-19. PMID 22218879 DOI: 10.1007/S00259-011-2045-0  0.251
2016 Dubois B, Hampel H, Feldman HH, Scheltens P, Aisen P, Andrieu S, Bakardjian H, Benali H, Bertram L, Blennow K, Broich K, Cavedo E, Crutch S, Dartigues JF, Duyckaerts C, ... ... Sperling R, et al. Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 12: 292-323. PMID 27012484 DOI: 10.1016/J.Jalz.2016.02.002  0.25
2014 Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, et al. Functional connectivity in autosomal dominant and late-onset Alzheimer disease. Jama Neurology. 71: 1111-22. PMID 25069482 DOI: 10.1001/Jamaneurol.2014.1654  0.25
2000 Greenberg SM, Tennis MK, Brown LB, Gomez-Isla T, Hayden DL, Schoenfeld DA, Walsh KL, Corwin C, Daffner KR, Friedman P, Meadows ME, Sperling RA, Growdon JH. Donepezil therapy in clinical practice: a randomized crossover study. Archives of Neurology. 57: 94-9. PMID 10634454 DOI: 10.1001/Archneur.57.1.94  0.25
2015 Hyman BT, Growdon JH, Albers MW, Buckner RL, Chhatwal J, Gomez-Isla MT, Haass C, Hudry E, Jack CR, Johnson KA, Khachaturian ZS, Kim DY, Martin JB, Nitsch RM, Rosen BR, ... ... Sperling RA, et al. Massachusetts Alzheimer's Disease Research Center: Progress and challenges. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26297855 DOI: 10.1016/J.Jalz.2015.06.1887  0.25
2006 Papp KV, Rentz DM, Maruff P, Sun C, Raman R, Donohue MC, Schembri A, Stark CE, Yassa MA, Holdridge KC, Wessels AM, Yaari R, Aisen PS, Sperling RA. P4-341: THE COMPUTERIZED COGNITIVE COMPOSITE (C3) AND AMYLOID STATUS AMONG NORMAL OLDER ADULTS Alzheimer's & Dementia. 14: P1597-P1598. DOI: 10.1016/J.Jalz.2018.07.164  0.25
2011 Reiman EM, McKhann GM, Albert MS, Sperling RA, Petersen RC, Blacker D. Alzheimer's disease: implications of the updated diagnostic and research criteria. The Journal of Clinical Psychiatry. 72: 1190-6. PMID 21951985 DOI: 10.4088/Jcp.10087Co1C  0.249
2021 Amariglio RE, Sikkes SAM, Marshall GA, Buckley RF, Gatchel JR, Johnson KA, Rentz DM, Donohue MC, Raman R, Sun CK, Yaari R, Holdridge KC, Sims JR, Grill JD, Aisen PS, ... Sperling RA, et al. Item-Level Investigation of Participant and Study Partner Report on the Cognitive Function Index from the A4 Study Screening Data. The Journal of Prevention of Alzheimer's Disease. 8: 257-262. PMID 34101781 DOI: 10.14283/jpad.2021.8  0.249
2012 DeCarli C, Kawas C, Morrison JH, Reuter-Lorenz PA, Sperling RA, Wright CB. Session II: Mechanisms of age-related cognitive change and targets for intervention: neural circuits, networks, and plasticity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 747-53. PMID 22570135 DOI: 10.1093/Gerona/Gls111  0.249
2006 Miller SL, Bates J, Blacker D, Sperling R, Dickerson BC. P2-362: Hippocampal activation in MCI predicts subsequent cognitive decline Alzheimer's & Dementia. 2: S349-S350. DOI: 10.1016/j.jalz.2006.05.1202  0.249
2019 Marshall GA, Sikkes SAM, Amariglio R, Gatchel JR, Rentz D, Johnson KA, Langford O, Sun C, Donohue MC, Raman R, Aisen PS, Sperling RA, Galasko DR, Team AS. P4-245: The Association Between Instrumental Activities Of Daily Living And Cortical Amyloid In Cognitively Normal Older Adults Screening For The A4 Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3908  0.249
2015 Papp KV, Mormino EC, Amariglio R, Schultz AP, Johnson KA, Sperling RA, Rentz DM. O2-02-05: Differential declines in letter versus category fluency over 4 years in biomarker-defined preclinical Alzheimer's disease Alzheimer's & Dementia. 11: P176-P177. DOI: 10.1016/j.jalz.2015.07.140  0.249
2012 McLaren D, Sperling R, Atri A. P2‐212: A biomarker signal: Context‐dependent hippocampal fMRI connectivity analysis of clinical trial measures in Alzheimer's disease Alzheimer's & Dementia. 8. DOI: 10.1016/j.jalz.2012.05.919  0.248
2008 Atri A, O'Brien JL, Rastegar S, DeLuca AN, O'Keefe KM, LaViolette PS, Diamond EL, Salisbury SL, Pihlajamaki MM, Locascio JJ, Rentz DM, Sperling RA. P1-219: Feasibility and test-retest reliability of fMRI in an Alzheimer's disease clinical trial Alzheimer's & Dementia. 4: T274-T274. DOI: 10.1016/j.jalz.2008.05.808  0.248
2012 McLaren D, Sperling R, Atri A. A biomarker signal: Context-dependent hippocampal fMRI connectivity analysis of clinical trial measures in Alzheimer's disease Alzheimers & Dementia. 8: 19. DOI: 10.1016/J.Jalz.2012.05.054  0.248
2015 Doody RS, Raman R, Sperling RA, Seimers E, Sethuraman G, Mohs R, Farlow M, Iwatsubo T, Vellas B, Sun X, Ernstrom K, Thomas RG, Aisen PS. Peripheral and central effects of γ-secretase inhibition by semagacestat in Alzheimer's disease. Alzheimer's Research & Therapy. 7: 36. PMID 26064192 DOI: 10.1186/S13195-015-0121-6  0.248
2018 Aisen PS, Siemers E, Michelson D, Salloway S, Sampaio C, Carrillo MC, Sperling R, Doody R, Scheltens P, Bateman R, Weiner M, Vellas B. What Have We Learned from Expedition III and EPOCH Trials? Perspective of the CTAD Task Force. The Journal of Prevention of Alzheimer's Disease. 5: 171-174. PMID 29972209 DOI: 10.14283/jpad.2018.23  0.247
2018 Salloway SP, Sperling R, Fox NC, Sabbagh MN, Honig LS, Porsteinsson AP, Rofael H, Ketter N, Wang D, Liu E, Carr S, Black RS, Brashear HR. Long-Term Follow Up of Patients with Mild-to-Moderate Alzheimer's Disease Treated with Bapineuzumab in a Phase III, Open-Label, Extension Study. Journal of Alzheimer's Disease : Jad. PMID 29914022 DOI: 10.3233/Jad-171157  0.247
2020 Guzmán-Vélez E, Martínez J, Papp K, Baena A, Vila-Castelar C, Artola A, Schultz AP, Bocanegra Y, Sanchez J, Rentz D, Tariot PN, Reiman EM, Sperling R, Johnson KA, Lopera F, et al. Associative memory and in vivo brain pathology in asymptomatic presenilin-1 E280A carriers. Neurology. PMID 32611637 DOI: 10.1212/Wnl.0000000000010177  0.247
2016 Hsu DC, Mormino EC, Schultz AP, Amariglio RE, Donovan NJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Lower Late-Life Body-Mass Index is Associated with Higher Cortical Amyloid Burden in Clinically Normal Elderly. Journal of Alzheimer's Disease : Jad. PMID 27340843 DOI: 10.3233/JAD-150987  0.247
2016 Gomperts SN, Locascio JJ, Makaretz SJ, Schultz A, Caso C, Vasdev N, Sperling R, Growdon JH, Dickerson BC, Johnson K. Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases. Jama Neurology. PMID 27654968 DOI: 10.1001/Jamaneurol.2016.3338  0.246
2010 Vannini P, Sullivan C, Schultz A, Putcha D, Vitolo O, Rentz D, Frey M, Becker AJ, Johnson KA, Sperling RA. O2-04-03: Increased amyloid deposition is related to failure of habituation of the default network but preserved repetition suppression in the hippocampus during successful repetition encoding in cognitively normal older adults Alzheimer's & Dementia. 6: S103-S104. DOI: 10.1016/j.jalz.2010.05.324  0.246
2014 Feldman HH, Haas M, Gandy S, Schoepp DD, Cross AJ, Mayeux R, Sperling RA, Fillit H, van de Hoef DL, Dougal S, Nye JS. Alzheimer's disease research and development: a call for a new research roadmap. Annals of the New York Academy of Sciences. 1313: 1-16. PMID 24754377 DOI: 10.1111/Nyas.12424  0.246
2015 Marshall GA, Munro C, Wigman SE, Dagley AS, Schultz AP, Amariglio R, Rentz DM, Johnson KA, Sperling RA. P3-162: Instrumental activities of daily living and functional connectivity in mild cognitive impairment Alzheimer's & Dementia. 11: P690-P691. DOI: 10.1016/j.jalz.2015.06.1533  0.246
2014 Karlawish J, Harkins K, Sankar P, Sperling R, Grill J, Green RC. P4‐069: DEVELOPMENT OF A PROCESS TO DISCLOSE AMYLOID IMAGING RESULTS TO COGNITIVELY NORMAL OLDER ADULT RESEARCH PARTICIPANTS Alzheimer's & Dementia. 10. DOI: 10.1016/j.jalz.2014.05.1584  0.246
2013 Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, ... ... Sperling RA, et al. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E4502-9. PMID 24194552 DOI: 10.1073/Pnas.1317918110  0.245
2016 Amariglio R, Mormino EC, Papp KV, Vannini P, Aghjayan SL, Marshall GA, Johnson K, Sperling RA, Rentz DM. P2-341: Subjective Cognitive Decline Predicts Longitudinal Decline in those with Both Amyloidosis and Neurodegeneration Alzheimer's & Dementia. 12: P773-P774. DOI: 10.1016/J.Jalz.2016.06.1471  0.245
2015 Chhatwal JP, Schultz AP, Marshall GA, Boot B, Gomez-Isla T, Dumurgier J, LaPoint M, Scherzer C, Roe AD, Hyman BT, Sperling RA, Johnson KA. IC-P-162: Entorhinal, parahippocampal, and inferior temporal F18-T807 SUVR correlates with CSF total tau and tau T181P in cognitively normal elderly Alzheimer's & Dementia. 11: P109-P109. DOI: 10.1016/j.jalz.2015.06.185  0.245
2015 Stephenson D, Perry D, Bens C, Bain LJ, Berry D, Krams M, Sperling R, Dilts D, Luthman J, Hanna D, McKew J, Temple R, Fields FO, Salloway S, Katz R. Charting a path toward combination therapy for Alzheimer's disease. Expert Review of Neurotherapeutics. 15: 107-13. PMID 25540951 DOI: 10.1586/14737175.2015.995168  0.245
2011 Becker J, Gidicsin C, Maye J, Sperling R, Johnson K. P4-470: Characterizing biomarker dynamics along the Alzheimer's disease trajectory Alzheimer's & Dementia. 7: e74-e74. DOI: 10.1016/J.Jalz.2011.09.163  0.245
2017 Norton DJ, Amariglio R, Protas H, Chen K, Aguirre-Acevedo DC, Pulsifer B, Castrillon G, Tirado V, Munoz C, Tariot P, Langbaum JB, Reiman EM, Lopera F, Sperling RA, Quiroz YT. Subjective memory complaints in preclinical autosomal dominant Alzheimer disease. Neurology. PMID 28878053 DOI: 10.1212/Wnl.0000000000004533  0.244
2011 Atri A, O'Brien JL, Sreenivasan A, Rastegar S, Salisbury S, DeLuca AN, O'Keefe KM, LaViolette PS, Rentz DM, Locascio JJ, Sperling RA. Test-retest reliability of memory task functional magnetic resonance imaging in Alzheimer disease clinical trials. Archives of Neurology. 68: 599-606. PMID 21555634 DOI: 10.1001/Archneurol.2011.94  0.244
2018 Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, ... ... Sperling RA, et al. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Acta Neuropathologica. PMID 30413934 DOI: 10.1007/S00401-018-1928-6  0.244
2014 Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M, Herrup K, Kawas C, Khachaturian AS, Khachaturian ZS, ... ... Sperling RA, et al. 2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S430-52. PMID 25341459 DOI: 10.1016/J.Jalz.2014.08.103  0.244
2013 Huijbers W, Ward A, Wigman S, Mormino E, Vannini P, Becker J, Schultz A, Johnson K, Hedden T, Sperling R. IC-P-013: Dissociations between entorhinal and hippocampal activity in cognitively normal older adults with and without beta-amyloid deposition Alzheimer's & Dementia. 9: P17-P17. DOI: 10.1016/J.Jalz.2013.05.014  0.244
2018 Hanseeuw BJ, Betensky RA, Mormino EC, Schultz AP, Sepulcre J, Becker JA, Jacobs HIL, Buckley RF, LaPoint MR, Vanini P, Donovan NJ, Chhatwal JP, Marshall GA, Papp KV, Amariglio RE, ... ... Sperling RA, et al. PET staging of amyloidosis using striatum. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29792874 DOI: 10.1016/J.Jalz.2018.04.011  0.243
2014 Samieri C, Proust-Lima C, M Glymour M, Okereke OI, Amariglio RE, Sperling RA, Rentz DM, Grodstein F. Subjective cognitive concerns, episodic memory, and the APOE ε4 allele. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 752-759.e1. PMID 25256133 DOI: 10.1016/j.jalz.2014.06.012  0.242
2006 Gatchel JR, Rabin JS, Buckley RF, Locascio JJ, Quiroz YT, Vannini P, Amariglio R, Rentz DM, Johnson KA, Blacker D, Donovan NJ, Sperling RA, Marshall GA. P1-327: LONGITUDINAL DEPRESSIVE SYMPTOMS AND CORTICAL AMYLOID ARE ASSOCIATED WITH COGNITIVE DECLINE IN OLDER ADULTS Alzheimer's & Dementia. 14: P417-P417. DOI: 10.1016/j.jalz.2018.06.334  0.242
2017 Aisen P, Touchon J, Amariglio R, Andrieu S, Bateman R, Breitner J, Donohue M, Dunn B, Doody R, Fox N, Gauthier S, Grundman M, Hendrix S, Ho C, Isaac M, ... ... Sperling R, et al. EU/US/CTAD Task Force: Lessons Learned from Recent and Current Alzheimer's Prevention Trials. The Journal of Prevention of Alzheimer's Disease. 4: 116-124. PMID 29186281 DOI: 10.14283/jpad.2017.13  0.242
2018 Yang HS, Yu L, White CC, Chibnik LB, Chhatwal JP, Sperling RA, Bennett DA, Schneider JA, De Jager PL. Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study. The Lancet. Neurology. PMID 30093249 DOI: 10.1016/S1474-4422(18)30251-5  0.241
2020 Scott MR, Schultz AP, Buckley RF, Chou HL, Hampton OL, Hanseeuw BJ, Jacobs HI, Properzi MJ, Rabin JS, Johnson KA, Sperling RA, Chhatwal JP. Associations of peak width of skeletonized mean diffusivity with cardiovascular disease risk and cognitive decline in clinically normal older adults Alzheimer's & Dementia. 16. DOI: 10.1002/alz.043812  0.24
2017 Hanseeuw BJ, McDade E, Schultz AP, Martins RN, Schofield PR, Masters CL, Graff-Radford NR, Salloway S, Danek A, Levin J, Buckles V, Goate AM, Benzinger TL, Morris JC, Bateman RJ, ... ... Sperling RA, et al. GENOTYPIC VARIANCE MAY EXPLAIN THE BALANCE OF EARLY CORTICAL VERSUS STRIATAL AMYLOID DEPOSITION IN AUTOSOMAL DOMINANT AD Alzheimer's & Dementia. 13: P187-P188. DOI: 10.1016/J.Jalz.2017.07.043  0.24
2016 Aisen P, Touchon J, Andrieu S, Boada M, Doody R, Nosheny RL, Langbaum JB, Schneider L, Hendrix S, Wilcock G, Molinuevo JL, Ritchie C, Ousset PJ, Cummings J, Sperling R, et al. Registries and Cohorts to Accelerate Early Phase Alzheimer's Trials. A Report from the E.U./U.S. Clinical Trials in Alzheimer's Disease Task Force. The Journal of Prevention of Alzheimer's Disease. 3: 68-74. PMID 29210442 DOI: 10.14283/jpad.2016.97  0.239
2013 Frisoni GB, Bocchetta M, Chételat G, Rabinovici GD, de Leon MJ, Kaye J, Reiman EM, Scheltens P, Barkhof F, Black SE, Brooks DJ, Carrillo MC, Fox NC, Herholz K, Nordberg A, ... ... Sperling RA, et al. Imaging markers for Alzheimer disease: which vs how. Neurology. 81: 487-500. PMID 23897875 DOI: 10.1212/Wnl.0B013E31829D86E8  0.239
2013 Bradshaw EM, Chibnik LB, Keenan BT, Ottoboni L, Raj T, Tang A, Rosenkrantz LL, Imboywa S, Lee M, Von Korff A, Morris MC, Evans DA, Johnson K, Sperling RA, et al. CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology. Nature Neuroscience. 16: 848-50. PMID 23708142 DOI: 10.1038/Nn.3435  0.239
2006 Atri A, Diamond EL, DePeau KM, Salisbury SL, Miller SL, Celone KA, Sardinha L, Gregas MC, Manning LN, Pihlajamaki M, Chen N, Searl MM, Rentz DM, Sperling RA. P2-326: Longitudinal change in FMRI activation correlates with change in clinical trial measures in Alzheimer's disease Alzheimer's & Dementia. 2: S336-S337. DOI: 10.1016/J.Jalz.2006.05.1166  0.239
2019 Guzman-Velez E, Martínez J, Papp KV, Baena A, Schultz AP, Bocanegra Y, Sanchez JS, Rentz DM, Reiman EM, Sperling RA, Johnson KA, Lopera F, Quiroz YT. P4-607: Free And Cued Memory Is Distinctly Related To Pathology In Preclinical Autosomal-Dominant Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.08.155  0.239
2018 Burnham SC, Bourgeat P, Budgeon CA, Dore V, Savage G, Laws SM, Salvado O, Maruff P, Martins RN, Ames D, Sperling RA, Masters CL, Rowe CC, Villemagne VL. O4-09-01: COMPARISON OF THE NATURAL HISTORY OF NEOCORTICAL Aβ-AMYLOID, HIPPOCAMPAL VOLUME AND PACC IN SPORADIC AD Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2957  0.239
2015 Chhatwal JP, Schultz AP, Marshall GA, Boot B, Gomez-Isla T, Dumurgier J, LaPoint M, Scherzer C, Roe AD, Hyman BT, Sperling RA, Johnson KA. O4-01-04: Entorhinal, parahippocampal, and inferior temporal F18-T807 SUVR correlates with CSF total tau and tau T181P in cognitively normal elderly Alzheimer's & Dementia. 11: P267-P267. DOI: 10.1016/J.Jalz.2015.07.348  0.238
2006 Buckley RF, Hanseeuw BJ, Mormino BC, Chhatwal JP, Schultz AP, Rabin JS, Rentz DM, Properzi MJ, Jacobs HI, Gomez-Isla T, Johnson KA, Sperling RA. O1-10-03: SEX AND APOE GENOTYPE INFLUENCE THE ASSOCIATION BETWEEN AMYLOID AND LONGITUDINAL TAU PATHOLOGY IN CLINICALLY NORMAL OLDER ADULTS: FINDINGS FROM THE ADNI STUDY Alzheimer's & Dementia. 14: P243-P244. DOI: 10.1016/J.Jalz.2018.06.2386  0.236
2020 Jimenez-Maggiora GA, Bruschi S, Raman R, Langford O, Donohue M, Rafii MS, Sperling RA, Cummings JL, Aisen PS. TRC-PAD: Accelerating Recruitment of AD Clinical Trials through Innovative Information Technology. The Journal of Prevention of Alzheimer's Disease. 7: 226-233. PMID 32920624 DOI: 10.14283/jpad.2020.48  0.236
2011 Lorius N, Locascio J, Rentz D, Johnson K, Sperling R, Blacker D, Viswanathan A, Marshall G. Vascular risk factors are associated with cognitive decline in mild cognitive impairment Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1693  0.235
2015 Guercio BJ, Donovan NJ, Munro CE, Aghjayan SL, Wigman SE, Locascio JJ, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. The Apathy Evaluation Scale: A Comparison of Subject, Informant, and Clinician Report in Cognitively Normal Elderly and Mild Cognitive Impairment Journal of Alzheimer's Disease. 47: 421-432. DOI: 10.3233/JAD-150146  0.235
2006 Gatchel JR, Rabin JS, Buckley RF, Locascio JJ, Quiroz YT, Vannini P, Amariglio R, Rentz DM, Blacker D, Johnson KA, Donovan NJ, Sperling RA, Marshall GA. IC-P-139: LONGITUDINAL DEPRESSIVE SYMPTOMS AND CORTICAL AMYLOID ARE ASSOCIATED WITH COGNITIVE DECLINE IN OLDER ADULTS Alzheimer's & Dementia. 14: P116-P117. DOI: 10.1016/j.jalz.2018.06.2205  0.234
2002 Budson AE, Michalska KJ, Rentz DM, Joubert CC, Daffner KR, Schacter DL, Sperling RA. Use of a false recognition paradigm in an Alzheimer's disease clinical trial: a pilot study. American Journal of Alzheimer's Disease and Other Dementias. 17: 93-100. PMID 11954675 DOI: 10.1177/153331750201700204  0.234
2006 Johnson KA, Pollen D, Rentz D, Moran E, Becker JA, Moonis M, Swearer J, Hyman B, Selkoe D, Sperling R, DeKosky S, Matthis C, Klunk W, Fischman A. IC-103-03: Amyloid deposition in presymptomatic familial Alzheimer's disease Alzheimer's & Dementia. 2: S653-S653. DOI: 10.1016/J.Jalz.2006.05.2198  0.234
2013 Yang T, Hong S, O'Malley T, Sperling RA, Walsh DM, Selkoe DJ. New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 99-112. PMID 23375565 DOI: 10.1016/J.Jalz.2012.11.005  0.234
2006 Keshavan A, Mengel D, Chen Z, Patel PP, Billinton A, Perkinton M, Percival-Alwyn JL, Zetterberg H, Johnson KA, Properzi M, Schultz AP, Sperling RA, Rissman RA, Galasko DR, Schott JM, et al. P1-301: CERTAIN PLASMA N-TERMINAL TAU FRAGMENTS ARE ELEVATED IN AD AND AD-MCI COMPARED TO CONTROLS Alzheimer's & Dementia. 14: P405-P405. DOI: 10.1016/J.Jalz.2018.06.308  0.234
2016 Papp KV, Mormino EC, Amariglio R, Sperling RA, Rentz DM, Johnson K, Schultz AP. O3-09-03: Associations between Amyloidosis and Longitudinal Cognitive Decline in Clinically Normal Older Adults Alzheimer's & Dementia. 12: P308-P308. DOI: 10.1016/J.Jalz.2016.06.557  0.233
2006 Dickerson BC, Hevelone N, Sperling RA, Albert MS, Blacker D. P2-073: Prediction of cognitive decline among very mild MCI cases Alzheimer's & Dementia. 2: S254-S254. DOI: 10.1016/J.Jalz.2006.05.910  0.233
2012 Benzinger T, Blazey T, Ances B, Raichle M, Ances B, Snyder A, Su Y, Marcus D, Ringman J, Thompson P, Ghetti B, Saykin A, Salloway S, Correia S, Johnson K, ... Sperling R, et al. IC-P-128: Progressive white matter abnormalities in autosomal dominant Alzheimer's disease: Results of the DIAN study Alzheimer's & Dementia. 8: P68-P69. DOI: 10.1016/j.jalz.2012.05.1858  0.233
2018 Brashear HR, Ketter N, Bogert J, Di J, Salloway SP, Sperling R. Clinical Evaluation of Amyloid-Related Imaging Abnormalities in Bapineuzumab Phase III Studies. Journal of Alzheimer's Disease : Jad. PMID 30412493 DOI: 10.3233/Jad-180675  0.232
2017 Buckley RF, Schultz AP, Papp KV, Properzi M, LaPoint MR, Rabin JS, Hedden T, Johnson K, Sperling RA, Rentz DM, Chhatwal JP. COGNITIVE RESERVE RELATES TO GREATER FUNCTIONAL CONNECTIVITY AND STRONGER INTERCONNECTIVITY WITHIN AND BETWEEN NODES, INDEPENDENT OF β-AMYLOID: FINDINGS FROM THE HARVARD AGING BRAIN STUDY Alzheimer's & Dementia. 13: P582-P583. DOI: 10.1016/J.Jalz.2017.07.207  0.232
2019 Jacobs HI, Dutta J, Becker A, Hanseeuw BJ, Sepulcre J, Sperling RA, Johnson KA. P3-414: LOCUS COERULEUS HYPERMETABOLISM IS ASSOCIATED WITH AMYLOID-RELATED MEDIAL TEMPORAL TAU PATHOLOGY Alzheimer's & Dementia. 15: P1113-P1114. DOI: 10.1016/J.Jalz.2019.06.3448  0.232
2007 Chappell AS, Gonzales C, Williams J, Witte MM, Mohs RC, Sperling R. AMPA potentiator treatment of cognitive deficits in Alzheimer disease. Neurology. 68: 1008-12. PMID 17389305 DOI: 10.1212/01.Wnl.0000260240.46070.7C  0.231
2018 Klinger RY, James OG, Borges-Neto S, Bisanar T, Li YJ, Qi W, Berger M, Terrando N, Newman MF, Doraiswamy PM, Mathew JP, Weiner MW, Aisen P, Weiner M, Aisen P, ... ... Sperling RA, ... ... Sperling RA, et al. 18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery. Anesthesiology. PMID 29389750 DOI: 10.1097/Aln.0000000000002103  0.231
2012 Teipel S, Sperling RA, Skudlarski P, Jack C, Hampel H, Fellgiebel A, Herholz K. MRI- and PET-based imaging markers for the diagnosis of Alzheimer's disease Advances in Biological Psychiatry. 28: 80-114. DOI: 10.1159/000335393  0.231
2019 Amariglio R, Sikkes SAM, Marshall GA, Buckley RF, Gatchel JR, Johnson KA, Rentz DM, Donohue MC, Raman R, Sun C, Aisen PS, Sperling RA. Item-Level Comparison Of Participant And Study Partner Report On The Cognitive Function Index By Amyloid Pet From The A4 Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4370  0.23
2012 Huijbers W, Vannini P, Sperling RA, C M P, Cabeza R, Daselaar SM. Explaining the encoding/retrieval flip: memory-related deactivations and activations in the posteromedial cortex. Neuropsychologia. 50: 3764-74. PMID 22982484 DOI: 10.1016/J.Neuropsychologia.2012.08.021  0.23
2016 Vannini P, Hanseeuw BJ, Munro CE, Amariglio R, Marshall GA, Rentz DM, Pascual-Leone A, Johnson K, Sperling RA. IC-P-043: Neuroimaging Correlates of Anosognosia in Mild Cognitive Impairment Alzheimer's & Dementia. 12: P36-P37. DOI: 10.1016/J.Jalz.2016.06.053  0.23
2008 Atri A, O'Brien JL, Rastegar S, DeLuca AN, O'Keefe KM, LaViolette PS, Diamond EL, Salisbury SL, Pihlajamaki MM, Locascio JJ, Rentz DM, Sperling RA. IC-P2-073: Feasibility and test-retest reliability of fMRI in an Alzheimer's disease clinical trial Alzheimer's & Dementia. 4: T37-T38. DOI: 10.1016/j.jalz.2008.05.066  0.23
2011 Khachaturian ZS, Petersen RC, Snyder PJ, Khachaturian AS, Aisen P, de Leon M, Greenberg BD, Kukull W, Maruff P, Sperling RA, Stern Y, Touchon J, Vellas B, Andrieu S, Weiner MW, et al. Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 127-32. PMID 21414553 DOI: 10.1016/J.Jalz.2011.02.005  0.229
2016 Lee S, Zimmerman ME, Viqar F, Narkhede A, Tosto G, Lee Smith Benzinger T, Marcus DS, Goate AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, Martins RN, ... ... Sperling RA, et al. O2-03-02: are White Matter Hyperintensities a Core Feature of Alzheimer’s Disease or Just a Reflection of Amyloid Angiopathy? Evidence From the Dominantly Inherited Alzheimer Network (DIAN) Alzheimer's & Dementia. 12: P226-P226. DOI: 10.1016/J.Jalz.2016.06.406  0.229
2006 Atri A, Diamond EL, DePeau KM, Salisbury SL, Miller SL, Celone KA, Sardinha L, Gregas MC, Manning LN, Pihlajamaki M, Chen N, Searl MM, Rentz DM, Sperling RA. IC-P-105: Longitudinal change in fMRI activation correlates with change in clinical trial measures in Alzheimer's disease Alzheimer's & Dementia. 2: S694-S695. DOI: 10.1016/J.Jalz.2006.05.2311  0.229
2004 Lange N, Lake S, Sperling R, Brown J, Routledge C, Albert M, Heckers S. Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research. Statistics in Medicine. 23: 327-50. PMID 14716733 DOI: 10.1002/Sim.1720  0.229
2021 Deters K, Napolioni V, Sperling RA, Greicius MD, Mayeux R, Hohman T, Mormino EC. Amyloid PET imaging in self-identified non-Hispanic Blacks from the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) Study. Neurology. PMID 33568538 DOI: 10.1212/WNL.0000000000011599  0.229
2015 Growdon ME, Schultz AP, Dagley AS, Amariglio RE, Hedden T, Rentz DM, Johnson KA, Sperling RA, Albers MW, Marshall GA. Odor identification and Alzheimer disease biomarkers in clinically normal elderly. Neurology. 84: 2153-60. PMID 25934852 DOI: 10.1212/WNL.0000000000001614  0.229
2016 Jackson JD, Rentz DM, Aghjayan SL, Buckley RF, Meneide T, Sperling RA, Amariglio R. P4‐354: Subjective Cognitive Concerns are Associated with Objective Memory Performance in Older Caucasian but not African‐American Persons Alzheimer's & Dementia. 12. DOI: 10.1016/j.jalz.2016.07.099  0.229
2009 Marshall GA, Carmasin JS, Hamdi I, Frey MT, Olson LE, Rentz DM, Sperling RA, Johnson KA. P1-132: Amyloid deposition and instrumental activities of daily living impairment in non-demented elderly Alzheimer's & Dementia. 5: P215-P215. DOI: 10.1016/j.jalz.2009.04.137  0.228
2006 Miller SL, Bates J, Blacker D, Sperling R, Dickerson BC. IC-P-081: Hippocampal activation in MCI predicts subsequent cognitive decline Alzheimer's & Dementia. 2: S685-S686. DOI: 10.1016/J.Jalz.2006.05.1202  0.228
2020 Raghavan NS, Dumitrescu L, Mormino E, Mahoney ER, Lee AJ, Gao Y, Bilgel M, Goldstein D, Harrison T, Engelman CD, Saykin AJ, Whelan CD, Liu JZ, Jagust W, Albert M, ... ... Sperling R, et al. Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease. Jama Neurology. PMID 32568366 DOI: 10.1001/Jamaneurol.2020.1760  0.228
2000 Sperling RA, Bates JC, Cocchiarella AJ, Rentz DM, Schacter DL, Rosen BR. Functional MRI studies of hippocampal activation in aging and AD Neurobiology of Aging. 21: 2. DOI: 10.1016/S0197-4580(00)82682-2  0.228
2006 Joe EB, Joseph-Mathurin N, Benzinger TL, Bateman RJ, McDade E, Ghetti BF, Levin J, Vöglein J, Fox NC, Sperling RA, Chhatwal JP, Noble J, Salloway S, Chui HC, Ringman JM. P4-094: OCCIPITAL TO GLOBAL PIB UPTAKE IS ASSOCIATED WITH THE PRESENCE OF MICROHEMORRHAGES AND MUTATIONS ASSOCIATED WITH CEREBRAL AMYLOID ANGIOPATHY IN THE DOMINANTLY INHERITED ALZHEIMER'S NETWORK Alzheimer's & Dementia. 14: P1472-P1473. DOI: 10.1016/J.Jalz.2018.06.2497  0.228
2021 Aisen PS, Bateman RJ, Carrillo M, Doody R, Johnson K, Sims JR, Sperling R, Vellas B. Platform Trials to Expedite Drug Development in Alzheimer's Disease: A Report from the EU/US CTAD Task Force. The Journal of Prevention of Alzheimer's Disease. 8: 306-312. PMID 34101788 DOI: 10.14283/jpad.2021.21  0.227
2006 Pihlajamaki M, Miller SM, DePeau KM, Celone KA, Bertram L, Tanzi RE, Dickerson BC, Albert MS, Blacker D, Sperling RA. IC-P-071: The effect of APOE-4 on fMRI deactivation in older controls, MCI subjects and AD patients Alzheimer's & Dementia. 2: S681-S681. DOI: 10.1016/J.Jalz.2006.05.2276  0.227
2005 Budson AE, Chong H, Sardinha LM, Salisbury S, Rentz DM, Sperling RA. [P-151]: Associative and item memory as outcome measures for Alzheimer's disease clinical trials: A pilot study Alzheimer's & Dementia. 1: S58-S58. DOI: 10.1016/J.Jalz.2005.06.212  0.227
2015 Jaimes SY, Donovan NJ, Hsu DC, Dagley AS, Schultz AP, Amariglio R, Rentz DM, Johnson KA, Sperling RA, Marshall GA. P3-135: Clinical and neuroimaging predictors of psychological well-being as measured by the purpose in life scale in cognitively normal older individuals Alzheimer's & Dementia. 11: P675-P676. DOI: 10.1016/j.jalz.2015.06.1003  0.226
2017 Mormino BC, Papp KV, Zhang X, Suna N, Sabuncu M, Johnson K, Sperling RA, Rentz DM, Yeo T. Heterogeneity In Neuroimaging Patterns Present Throughout The Clinical Spectrum Of Typical Late-Onset Amnestic Ad Alzheimers & Dementia. 13: 1210. DOI: 10.1016/J.Jalz.2017.07.375  0.226
2015 Marshall GA, Munro C, Wigman SE, Dagley AS, Schultz AP, Amariglio R, Rentz DM, Johnson KA, Sperling RA. IC-P-071: Instrumental activities of daily living and functional connectivity in mild cognitive impairment Alzheimer's & Dementia. 11: P53-P53. DOI: 10.1016/j.jalz.2015.06.092  0.226
2019 Bocanegra Y, Guzman-Velez E, Baena A, Vila-Castelar C, Artola A, Gatchel JR, Pardilla-Delgado E, Fuller J, Sperling RA, Johnson KA, Lopera F, Quiroz YT. P4-608: Tau Accumulation And Visual Memory In Cognitively Unimpaired Psen1 E280A Mutation Carriers Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.08.156  0.225
2016 Vannini P, Hanseeuw BJ, Munro CE, Amariglio R, Marshall GA, Rentz DM, Pascual-Leone A, Johnson K, Sperling RA. O4-06-04: Neuroimaging Correlates of Anosognosia in Mild Cognitive Impairment Alzheimer's & Dementia. 12: P345-P346. DOI: 10.1016/j.jalz.2016.06.640  0.225
2011 Quiroz Y, Sperling R, Lopera F, Fleisher A, Chen K, Tirado V, Munoz C, Langbaum J, Tariot P, Stern C, Reiman E. P1-337: Task-dependent fMRI abnormalities in young adults at genetic risk for early-onset Alzheimer's disease Alzheimer's & Dementia. 7: S219-S220. DOI: 10.1016/j.jalz.2011.05.617  0.225
2017 Orlovsky I, Mormino BC, Huijbers W, Schultz AP, Rentz DM, Sperling RA, Johnson K, Papp KV. THE RELATIONSHIP BETWEEN RECALL OF RECENTLY VERSUS REMOTELY ENCODED FAMOUS FACES AND AMYLOID AND TAU BURDEN IN CLINICALLY NORMAL OLDER ADULTS Alzheimer's & Dementia. 13: P917. DOI: 10.1016/J.Jalz.2017.07.343  0.225
2006 Rand-Giovannetti E, Chua EF, Driscoll AE, Schacter DL, Albert MS, Sperling RA. Hippocampal and neocortical activation during repetitive encoding in older persons. Neurobiology of Aging. 27: 173-82. PMID 16298252 DOI: 10.1016/J.Neurobiolaging.2004.12.013  0.224
2019 Sikkes SA, Scott MR, Quiroz YT, Hanseeuw BJ, Amariglio R, Farrell ME, Gatchel JR, Papp KV, Marshall GA, Rentz DM, Johnson KA, Sperling RA, Vannini P. O3-06-04: EVOLUTION AND PATHOLOGICAL BASIS OF ALTERED MEMORY SELF-AWARENESS IN COGNITIVELY NORMAL OLDER ADULTS Alzheimer's & Dementia. 15: P895-P896. DOI: 10.1016/j.jalz.2019.06.4657  0.224
2006 Pihlajamaki M, Miller SM, DePeau KM, Celone KA, Bertram L, Tanzi RE, Dickerson BC, Albert MS, Blacker D, Sperling RA. O4-01-02: The effect of APOE-4 on fMRI deactivation in older controls, MCI subjects and AD patients Alzheimer's & Dementia. 2: S74-S75. DOI: 10.1016/J.Jalz.2006.05.292  0.224
2020 Yang H, Zhang C, Carlyle BC, Zhen SY, Trombetta BA, Schultz AP, Pruzin JJ, Fitzpatrick CD, Kirn D, Rentz DM, Arnold SE, Johnson KA, Chhatwal JP, Sperling RA, Tanzi RE. Plasma IL‐12/IFN‐γ axis predicts cognitive trajectories in cognitively normal older adults Alzheimer's & Dementia. 16. DOI: 10.1002/alz.045497  0.224
2014 Johnson KA, Schultz A, Becker A, Hyman B, Rentz D, Sepulcre J, Vasdev N, Sperling R, Brady T. Tau Pet Using F18-T807: Initial Experience In Normal Elderly And Ad Dementia Alzheimers & Dementia. 10: 242. DOI: 10.1016/J.Jalz.2014.04.365  0.224
2011 Wadsworth LP, Rentz D, Lorius N, Johnson K, Sperling R, Locascio J, Donvan N, Marshall G. Neuropsychiatric Symptoms are Associated with Current and Future Global Functional Impairment in Mild Cognitive Impairment Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.456  0.224
2012 Sperling R, Donohue M, Aisen P. F3-04-01: The A4 trial: Anti-amyloid treatment of asymptomatic Alzheimer's disease Alzheimer's & Dementia. 8: P425-P426. DOI: 10.1016/j.jalz.2012.05.1134  0.223
2019 Protas H, Pardilla-Delgado E, Lopera F, Johnson KA, Sperling RA, Artola A, Baena A, Bocanegra Y, Gatchel JR, Guzman-Velez E, Fuller J, Goradia DD, Thiyyagura P, VanGilder PS, Luo J, et al. IC-P-058: COVARYING SPATIAL PATTERNS OF TAU DEPOSITION AND GRAY MATTER ATROPHY UNEARTHED BY THE INFORMED MULTIMODAL PARTIAL LEAST SQUARES (MMPLS) IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE: FINDINGS FROM THE COLBOS PROJECT Alzheimer's & Dementia. 15: P58-P58. DOI: 10.1016/j.jalz.2019.06.4901  0.222
2019 Protas H, Pardilla-Delgado E, Lopera F, Johnson KA, Sperling RA, Artola A, Baena A, Bocanegra Y, Gatchel JR, Guzman-Velez E, Fuller J, Goradia DD, Thiyyagura P, VanGilder PS, Luo J, et al. Ic-P-058: Covarying Spatial Patterns Of Tau Deposition And Gray Matter Atrophy Unearthed By The Informed Multimodal Partial Least Squares (Mmpls) In Autosomal Dominant Alzheimer'S Disease: Findings From The Colbos Project Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2767  0.222
2019 Buckley RF, Sikkes SA, Wolfsgruber S, Ebenau J, Sánchez-Benavides G, Rami L, Rentz DM, Gifford KA, Wagner M, Sperling RA, Molinuevo JL, Jessen F, van der Flier WM, Amariglio R. FREQUENCY OF SUBJECTIVE COGNITIVE DECLINE CRITERIA IN STAGE 2 OF THE NEW NIA-AA FRAMEWORK: A MULTI-COHORT STUDY FROM THE SUBJECTIVE COGNITIVE DECLINE PROFESSIONAL INTEREST AREA Alzheimer's & Dementia. 15: P180-P181. DOI: 10.1016/j.jalz.2019.06.4381  0.222
2017 Kilpatrick EP, Buckley RF, Marshall GA, Klein H, Properzi M, Schultz AP, Rao V, Rabin JS, Hanseeuw BJ, Rentz DM, Hedden T, Sperling RA, Johnson K, Chhatwal JP. [P3-376]: QRISK2 AND FRAMINGHAM CARDIOVASCULAR RISK SCORES SIGNIFICANTLY CORRELATE WITH IMAGING BIOMARKERS OF PRECLINICAL AD: FINDINGS FROM THE HARVARD AGING BRAIN STUDY Alzheimer's & Dementia. 13: P1103-P1103. DOI: 10.1016/J.Jalz.2017.06.1592  0.222
2016 Donovan NJ, Wu Q, Rentz DM, Sperling RA, Marshall GA, Glymour MM. Loneliness, depression and cognitive function in older U.S. adults. International Journal of Geriatric Psychiatry. PMID 27162047 DOI: 10.1002/gps.4495  0.222
2015 Donovan NJ, Hsu DC, Dagley AS, Schultz AP, Amariglio RE, Mormino EC, Okereke OI, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Depressive symptoms and biomarkers of alzheimer’s disease in cognitively normal older adults Handbook of Depression in Alzheimer's Disease. 205-215. DOI: 10.3233/978-1-61499-542-5-205  0.222
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Sperling RA, et al. Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0163669. PMID 27649320 DOI: 10.1371/journal.pone.0163669  0.221
2015 Hayes SM, Alosco ML, Hayes JP, Cadden M, Peterson KM, Allsup K, Forman DE, Sperling RA, Verfaellie M. Physical Activity Is Positively Associated with Episodic Memory in Aging. Journal of the International Neuropsychological Society : Jins. 21: 780-90. PMID 26581790 DOI: 10.1017/S1355617715000910  0.22
2012 Naylor MD, Karlawish JH, Arnold SE, Khachaturian AS, Khachaturian ZS, Lee VM, Baumgart M, Banerjee S, Beck C, Blennow K, Brookmeyer R, Brunden KR, Buckwalter KC, Comer M, Covinsky K, ... ... Sperling RA, et al. Advancing Alzheimer's disease diagnosis, treatment, and care: recommendations from the Ware Invitational Summit. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 445-52. PMID 22959699 DOI: 10.1016/J.Jalz.2012.08.001  0.219
2015 Jaimes SY, Donovan NJ, Hsu DC, Dagley AS, Schultz AP, Amariglio R, Rentz DM, Johnson KA, Sperling RA, Marshall GA. IC-P-153: Clinical and neuroimaging predictors of psychological well-being as measured by the purpose in life scale in cognitively normal older individuals Alzheimer's & Dementia. 11: P102-P103. DOI: 10.1016/j.jalz.2015.06.176  0.218
2013 Langbaum J, High N, Aisen P, Albert M, Brown K, Comer M, Cummings J, Manly J, Petersen R, Sperling R, Strobel G, Weiner M, Tariot P, Reiman E. Development and implementation of the National Alzheimer's Prevention Registry Alzheimers & Dementia. 9: 280. DOI: 10.1016/J.Jalz.2013.05.560  0.218
2014 Marder TJ, Flores VL, Bolo NR, Hoogenboom WS, Simonson DC, Jacobson AM, Foote SE, Shenton ME, Sperling RA, Musen G. Task-induced brain activity patterns in type 2 diabetes: a potential biomarker for cognitive decline. Diabetes. 63: 3112-9. PMID 24705405 DOI: 10.2337/Db13-1783  0.218
2017 Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Dietzsch J, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Graff-Radford NR, Levin J, Galasko D, ... ... Sperling R, et al. Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease. Scientific Reports. 7: 1225. PMID 28450713 DOI: 10.1038/S41598-017-01327-W  0.218
2019 Gauthier S, Alam J, Fillit H, Iwatsubo T, Liu-Seifert H, Sabbagh M, Salloway S, Sampaio C, Sims JR, Sperling B, Sperling R, Welsh-Bohmer KA, Touchon J, Vellas B, Aisen P. Combination Therapy for Alzheimer's Disease: Perspectives of the EU/US CTAD Task Force. The Journal of Prevention of Alzheimer's Disease. 6: 164-168. PMID 31062826 DOI: 10.14283/jpad.2019.12  0.218
2016 Gatchel JR, Donovan NJ, Blacker D, Schultz AP, Becker A, Chhatwal J, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Investigating the Association between Depressive Symptoms and Cortical Tau Across the Alzheimer's Disease Spectrum The American Journal of Geriatric Psychiatry. 24: S96-S97. DOI: 10.1016/J.Jagp.2016.01.096  0.217
2020 Engels N, Prokopiou PC, Uquillas Fd, Scott MR, Schultz AP, Papp KV, Farrell ME, Rentz DM, Sperling RA, Johnson KA, Jacobs HI. Hypoconnectivity between locus coeruleus and medial temporal lobe during novelty predicts accelerated Aβ‐related cognitive decline Alzheimer's & Dementia. 16. DOI: 10.1002/alz.041323  0.217
2019 Gatchel JR, Sikkes SA, van de Wiel MA, Donovan NJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA, Amariglio R. P2-269: GERIATRIC DEPRESSION SCALE ITEM-LEVEL ANALYSIS IN RELATION TO IN VIVO CORTICAL AMYLOID AND CEREBRAL REGIONAL TAU IN CLINICALLY NORMAL OLDER ADULTS: FINDINGS FROM THE HARVARD AGING BRAIN STUDY Alzheimer's & Dementia. 15: P690-P690. DOI: 10.1016/j.jalz.2019.06.2676  0.217
2011 Quiroz Y, Sperling R, Lopera F, Fleisher A, Chen K, Tirado V, Munoz C, Langbaum J, Tariot P, Stern C, Reiman E. IC-P-066: Task-dependent fMRI abnormalities in young adults at genetic risk for early-onset Alzheimer's disease Alzheimer's & Dementia. 7: S34-S35. DOI: 10.1016/J.Jalz.2011.05.132  0.216
2016 Jonas VH, Vannini P, Jackson JD, Gatchel JR, Rentz DM, Marshall GA, Johnson KA, Sperling RA, Donovan NJ. O1-13-01: Anxiety, Social Activity and Amyloid in Cognitively Normal Older Adults Alzheimer's & Dementia. 12: P208-P208. DOI: 10.1016/j.jalz.2016.06.364  0.216
2015 Donovan NJ, Wu Q, Rentz DM, Sperling RA, Marshall GA, Glymour MM. O2-11-06: Reciprocal relations of loneliness and cognitive function in older u.s. adults Alzheimer's & Dementia. 11: P201-P202. DOI: 10.1016/j.jalz.2015.07.194  0.216
2021 Berkness T, Carrillo MC, Sperling R, Petersen R, Aisen P, Flournoy C, Snyder H, Raman R, Grill JD. The Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD): A Novel Clinical Trials Training Program. The Journal of Prevention of Alzheimer's Disease. 8: 286-291. PMID 34101785 DOI: 10.14283/jpad.2021.12  0.216
2010 Sperling RA, Doraiswamy PM, Johnson K, Reiman EM, Sabbagh MN, Sadowsky CH, Carpenter A, Clark CM, Flitter M, Pontecorvo MJ, Skovronsky DM. O1-02-04: Florbetapir F 18 (18 F-AV-45) PET amyloid imaging predicts progression of cognitive impairment: A longitudinal clinical follow up study Alzheimer's & Dementia. 6: S71-S71. DOI: 10.1016/J.Jalz.2010.05.212  0.215
2010 Atri A, Dodd JS, Sreenivasan A, Vannini P, O'Brien JL, LaViolette P, Sperling RA. O2-04-06: A candidate fMRI measure combining hipppocampal and default mode network activity to predict future memory performance in Alzheimer's disease Alzheimer's & Dementia. 6: S105-S105. DOI: 10.1016/J.Jalz.2010.05.327  0.214
2000 Rentz DM, Calvo VL, Scinto LFM, Sperling RA, Budson AE, Daffner KR. Detecting early cognitive decline in high-functioning elders Journal of Geriatric Psychiatry. 33: 27-49.  0.214
2019 Gatchel JR, Sikkes SA, van de Wiel MA, Donovan NJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA, Amariglio R. IC-P-037: GERIATRIC DEPRESSION SCALE ITEM-LEVEL ANALYSIS IN RELATION TO IN VIVO CORTICAL AMYLOID AND CEREBRAL REGIONAL TAU IN CLINICALLY NORMAL OLDER ADULTS: FINDINGS FROM THE HARVARD AGING BRAIN STUDY Alzheimer's & Dementia. 15: P43-P43. DOI: 10.1016/j.jalz.2019.06.4199  0.213
1992 Johnson KA, Sperling RA, Holman BL, Nagel JS, Growdon JH. Cerebral perfusion in progressive supranuclear palsy. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 33: 704-9. PMID 1569479  0.213
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