| Year |
Citation |
Score |
| 2020 |
Hazell AS, Butterworth RF. Region-selective permeability of the blood-brain barrier to α-aminoisobutyric acid during thiamine deficiency and following its reversal. Metabolic Brain Disease. PMID 33245475 DOI: 10.1007/s11011-020-00644-w |
0.527 |
|
| 2017 |
de Moura TC, Afadlal S, Hazell AS. Potential for stem cell treatment in manganism. Neurochemistry International. PMID 29032009 DOI: 10.1016/J.Neuint.2017.10.005 |
0.403 |
|
| 2017 |
Silva VR, Secolin R, Vemuganti R, Lopes-Cendes I, Hazell AS. Acute liver failure is associated with altered cerebral expression profiles of long non-coding RNAs. Neuroscience Letters. PMID 28648459 DOI: 10.1016/J.Neulet.2017.06.038 |
0.607 |
|
| 2017 |
Hazell AS, Afadlal S, Cheresh D, Azar A. TREATMENT OF RATS WITH THE JAK-2 INHIBITOR FEDRATINIB DOES NOT LEAD TO EXPERIMENTAL WERNICKE's ENCEPHALOPATHY. Neuroscience Letters. PMID 28109775 DOI: 10.1016/J.Neulet.2017.01.041 |
0.389 |
|
| 2017 |
Hood J, Hazell A. Fedratinib Does Not Inhibit Thiamine Uptake or Induce Experimental Wernicke's Encephalopathy in Nonclinical Studies Blood. 130: 4993-4993. DOI: 10.1182/Blood.V130.Suppl_1.4993.4993 |
0.387 |
|
| 2016 |
Hazell AS. The Vegetative State and Stem Cells: Therapeutic Considerations. Frontiers in Neurology. 7: 118. PMID 27602016 DOI: 10.3389/Fneur.2016.00118 |
0.306 |
|
| 2015 |
Vemuganti R, Silva VR, Mehta SL, Hazell AS. Erratum to: Acute liver failure-induced hepatic encephalopathy is associated with changes in microRNA expression profiles in cerebral cortex of the mouse. Metabolic Brain Disease. 30: 247. PMID 25537182 DOI: 10.1007/S11011-014-9644-Y |
0.576 |
|
| 2015 |
Abdou E, Hazell AS. Thiamine deficiency: an update of pathophysiologic mechanisms and future therapeutic considerations. Neurochemical Research. 40: 353-61. PMID 25297573 DOI: 10.1007/S11064-014-1430-Z |
0.494 |
|
| 2014 |
Vemuganti R, Hazell AS. Mechanisms of hepatic encephalopathy and thiamine deficiency. Metabolic Brain Disease. 29: 889-90. PMID 24972879 DOI: 10.1007/S11011-014-9579-3 |
0.595 |
|
| 2014 |
Afadlal S, Labetoulle R, Hazell AS. Role of astrocytes in thiamine deficiency. Metabolic Brain Disease. 29: 1061-8. PMID 24929329 DOI: 10.1007/S11011-014-9571-Y |
0.487 |
|
| 2014 |
Vemuganti R, Silva VR, Mehta SL, Hazell AS. Acute liver failure-induced hepatic encephalopathy is associated with changes in microRNA expression profiles in cerebral cortex of the rat. Metabolic Brain Disease. 29: 891-9. PMID 24861182 DOI: 10.1007/S11011-014-9545-0 |
0.549 |
|
| 2014 |
Jhala SS, Wang D, Hazell AS. Thiamine deficiency results in release of soluble factors that disrupt mitochondrial membrane potential and downregulate the glutamate transporter splice-variant GLT-1b in cultured astrocytes. Biochemical and Biophysical Research Communications. 448: 335-41. PMID 24735535 DOI: 10.1016/J.Bbrc.2014.04.017 |
0.769 |
|
| 2014 |
Hazell AS, Wang D, Oanea R, Sun S, Aghourian M, Yong JJ. Pyrithiamine-induced thiamine deficiency alters proliferation and neurogenesis in both neurogenic and vulnerable areas of the rat brain. Metabolic Brain Disease. 29: 145-52. PMID 24078061 DOI: 10.1007/S11011-013-9436-9 |
0.426 |
|
| 2013 |
Hazell AS, Faim S, Wertheimer G, Silva VR, Marques CS. The impact of oxidative stress in thiamine deficiency: a multifactorial targeting issue. Neurochemistry International. 62: 796-802. PMID 23333339 DOI: 10.1016/J.Neuint.2013.01.009 |
0.399 |
|
| 2011 |
Jhala SS, Wang D, Hazell AS. Loss of the glutamate transporter splice-variant GLT-1b in inferior colliculus and its prevention by ceftriaxone in thiamine deficiency. Neurochemistry International. 58: 558-63. PMID 21256174 DOI: 10.1016/J.Neuint.2011.01.014 |
0.778 |
|
| 2011 |
Jhala SS, Hazell AS. Modeling neurodegenerative disease pathophysiology in thiamine deficiency: consequences of impaired oxidative metabolism. Neurochemistry International. 58: 248-60. PMID 21130821 DOI: 10.1016/J.Neuint.2010.11.019 |
0.772 |
|
| 2011 |
Hazell AS, Wang D. Identification of complexin II in astrocytes: a possible regulator of glutamate release in these cells. Biochemical and Biophysical Research Communications. 404: 228-32. PMID 21110949 DOI: 10.1016/J.Bbrc.2010.11.098 |
0.362 |
|
| 2010 |
Wang D, Hazell AS. Microglial activation is a major contributor to neurologic dysfunction in thiamine deficiency. Biochemical and Biophysical Research Communications. 402: 123-8. PMID 20932820 DOI: 10.1016/J.Bbrc.2010.09.128 |
0.419 |
|
| 2010 |
Beauchesne E, Desjardins P, Butterworth RF, Hazell AS. Up-regulation of caveolin-1 and blood-brain barrier breakdown are attenuated by N-acetylcysteine in thiamine deficiency. Neurochemistry International. 57: 830-7. PMID 20816907 DOI: 10.1016/J.Neuint.2010.08.022 |
0.594 |
|
| 2010 |
Hazell AS, Sheedy D, Oanea R, Aghourian M, Sun S, Jung JY, Wang D, Wang C. Loss of astrocytic glutamate transporters in Wernicke encephalopathy. Glia. 58: 148-56. PMID 19565658 DOI: 10.1002/Glia.20908 |
0.514 |
|
| 2009 |
Beauchesne E, Desjardins P, Hazell AS, Butterworth RF. eNOS gene deletion restores blood-brain barrier integrity and attenuates neurodegeneration in the thiamine-deficient mouse brain. Journal of Neurochemistry. 111: 452-9. PMID 19686244 DOI: 10.1111/J.1471-4159.2009.06338.X |
0.586 |
|
| 2009 |
Beauchesne E, Desjardins P, Hazell AS, Butterworth RF. Altered expression of tight junction proteins and matrix metalloproteinases in thiamine-deficient mouse brain. Neurochemistry International. 55: 275-81. PMID 19576514 DOI: 10.1016/J.Neuint.2009.03.014 |
0.583 |
|
| 2009 |
Hazell AS. Astrocytes are a major target in thiamine deficiency and Wernicke's encephalopathy. Neurochemistry International. 55: 129-35. PMID 19428817 DOI: 10.1016/J.Neuint.2009.02.020 |
0.499 |
|
| 2009 |
Hazell AS, Butterworth RF. Update of cell damage mechanisms in thiamine deficiency: focus on oxidative stress, excitotoxicity and inflammation. Alcohol and Alcoholism (Oxford, Oxfordshire). 44: 141-7. PMID 19151161 DOI: 10.1093/Alcalc/Agn120 |
0.58 |
|
| 2008 |
Hazell AS, Normandin L. Up-regulation of `peripheral-type' benzodiazepine receptors in the globus pallidus in manganese neurotoxicity Journal of Neurochemistry. 81: 101-105. DOI: 10.1046/J.1471-4159.81.S1.40_14.X |
0.442 |
|
| 2008 |
Navarro D, Zwingmann C, Hazell AS, Leibfritz D, Butterworth RF. Poster Sessions BP01: Energy Metabolism Journal of Neurochemistry. 81: 45-45. DOI: 10.1046/J.1471-4159.81.S1.14_1.X |
0.56 |
|
| 2007 |
Zwingmann C, Leibfritz D, Hazell AS. Nmr spectroscopic analysis of regional brain energy metabolism in manganese neurotoxicity. Glia. 55: 1610-7. PMID 17823966 DOI: 10.1002/Glia.20575 |
0.416 |
|
| 2007 |
Hazell AS. Excitotoxic mechanisms in stroke: an update of concepts and treatment strategies. Neurochemistry International. 50: 941-53. PMID 17576023 DOI: 10.1016/J.Neuint.2007.04.026 |
0.403 |
|
| 2007 |
Yi JH, Herrero R, Chen G, Hazell AS. Glutamate transporter EAAT4 is increased in hippocampal astrocytes following lateral fluid-percussion injury in the rat. Brain Research. 1154: 200-5. PMID 17490622 DOI: 10.1016/J.Brainres.2007.04.011 |
0.63 |
|
| 2007 |
Rama Rao KV, Reddy PV, Hazell AS, Norenberg MD. Manganese induces cell swelling in cultured astrocytes. Neurotoxicology. 28: 807-12. PMID 17408748 DOI: 10.1016/J.Neuro.2007.03.001 |
0.461 |
|
| 2006 |
Vemuganti R, Kalluri H, Yi JH, Bowen KK, Hazell AS. Gene expression changes in thalamus and inferior colliculus associated with inflammation, cellular stress, metabolism and structural damage in thiamine deficiency. The European Journal of Neuroscience. 23: 1172-88. PMID 16553781 DOI: 10.1111/J.1460-9568.2006.04651.X |
0.715 |
|
| 2006 |
Yi JH, Hazell AS. Excitotoxic mechanisms and the role of astrocytic glutamate transporters in traumatic brain injury. Neurochemistry International. 48: 394-403. PMID 16473439 DOI: 10.1016/J.Neuint.2005.12.001 |
0.621 |
|
| 2006 |
Yi JH, Hoover R, McIntosh TK, Hazell AS. Early, transient increase in complexin I and complexin II in the cerebral cortex following traumatic brain injury is attenuated by N-acetylcysteine. Journal of Neurotrauma. 23: 86-96. PMID 16430375 DOI: 10.1089/Neu.2006.23.86 |
0.559 |
|
| 2006 |
Hazell AS, Normandin L, Norenberg MD, Kennedy G, Yi JH. Alzheimer type II astrocytic changes following sub-acute exposure to manganese and its prevention by antioxidant treatment. Neuroscience Letters. 396: 167-71. PMID 16384640 DOI: 10.1016/J.Neulet.2005.11.064 |
0.606 |
|
| 2005 |
Bémeur C, Ste-Marie L, Desjardins P, Vachon L, Butterworth RF, Hazell AS, Montgomery J. Dehydroascorbic acid normalizes several markers of oxidative stress and inflammation in acute hyperglycemic focal cerebral ischemia in the rat. Neurochemistry International. 46: 399-407. PMID 15737438 DOI: 10.1016/J.Neuint.2004.11.007 |
0.532 |
|
| 2005 |
Yi JH, Hazell AS. N-acetylcysteine attenuates early induction of heme oxygenase-1 following traumatic brain injury. Brain Research. 1033: 13-9. PMID 15680334 DOI: 10.1016/J.Brainres.2004.10.055 |
0.599 |
|
| 2005 |
Navarro D, Zwingmann C, Hazell AS, Butterworth RF. Brain lactate synthesis in thiamine deficiency: a re-evaluation using 1H-13C nuclear magnetic resonance spectroscopy. Journal of Neuroscience Research. 79: 33-41. PMID 15573405 DOI: 10.1002/Jnr.20290 |
0.582 |
|
| 2005 |
Hazell AS, Wang C. Downregulation of complexin I and complexin II in the medial thalamus is blocked by N-acetylcysteine in experimental Wernicke's encephalopathy. Journal of Neuroscience Research. 79: 200-7. PMID 15573404 DOI: 10.1002/Jnr.20278 |
0.466 |
|
| 2005 |
Yi JH, Pow DV, Hazell AS. Early loss of the glutamate transporter splice-variant GLT-1v in rat cerebral cortex following lateral fluid-percussion injury. Glia. 49: 121-33. PMID 15390098 DOI: 10.1002/Glia.20099 |
0.632 |
|
| 2005 |
Yi J, Herrero R, Wang C, Hazell AS. Spatio-temporal profile of small heat-shock protein Hsp27 induction in rat brain following fluid-percussion injury to the lateral parietotemporal cerebral cortex; involvement with beta actin Journal of Cerebral Blood Flow & Metabolism. 25: S523-S523. DOI: 10.1038/Sj.Jcbfm.9591524.0523 |
0.593 |
|
| 2004 |
Bémeur C, Ste-Marie L, Desjardins P, Butterworth RF, Vachon L, Montgomery J, Hazell AS. Expression of superoxide dismutase in hyperglycemic focal cerebral ischemia in the rat. Neurochemistry International. 45: 1167-74. PMID 15380626 DOI: 10.1016/J.Neuint.2004.06.010 |
0.569 |
|
| 2004 |
Chan H, Butterworth RF, Hazell AS. Primary cultures of rat astrocytes respond to thiamine deficiency-induced swelling by downregulating aquaporin-4 levels. Neuroscience Letters. 366: 231-4. PMID 15288424 DOI: 10.1016/J.Neulet.2004.04.095 |
0.6 |
|
| 2004 |
Zwingmann C, Leibfritz D, Hazell AS. Brain energy metabolism in a sub-acute rat model of manganese neurotoxicity: an ex vivo nuclear magnetic resonance study using [1-13C]glucose. Neurotoxicology. 25: 573-87. PMID 15183011 DOI: 10.1016/J.Neuro.2003.08.002 |
0.403 |
|
| 2004 |
Bémeur C, Ste-Marie L, Desjardins P, Hazell AS, Vachon L, Butterworth R, Montgomery J. Decreased beta-actin mRNA expression in hyperglycemic focal cerebral ischemia in the rat. Neuroscience Letters. 357: 211-4. PMID 15003287 DOI: 10.1016/J.Neulet.2003.12.081 |
0.508 |
|
| 2003 |
Hazell AS, Normandin L, Nguyen B, Kennedy G. Upregulation of 'peripheral-type' benzodiazepine receptors in the globus pallidus in a sub-acute rat model of manganese neurotoxicity. Neuroscience Letters. 349: 13-6. PMID 12946575 DOI: 10.1016/S0304-3940(03)00649-9 |
0.432 |
|
| 2003 |
Hazell AS, Pannunzio P, Rama Rao KV, Pow DV, Rambaldi A. Thiamine deficiency results in downregulation of the GLAST glutamate transporter in cultured astrocytes. Glia. 43: 175-84. PMID 12838509 DOI: 10.1002/Glia.10241 |
0.458 |
|
| 2003 |
Zwingmann C, Leibfritz D, Hazell AS. Energy metabolism in astrocytes and neurons treated with manganese: relation among cell-specific energy failure, glucose metabolism, and intercellular trafficking using multinuclear NMR-spectroscopic analysis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 756-71. PMID 12796724 DOI: 10.1097/01.Wcb.0000056062.25434.4D |
0.381 |
|
| 2003 |
Desjardins P, Sauvageau A, Bouthillier A, Navarro D, Hazell AS, Rose C, Butterworth RF. Induction of astrocytic cyclooxygenase-2 in epileptic patients with hippocampal sclerosis. Neurochemistry International. 42: 299-303. PMID 12470703 DOI: 10.1016/S0197-0186(02)00101-8 |
0.665 |
|
| 2002 |
Normandin L, Hazell AS. Manganese neurotoxicity: an update of pathophysiologic mechanisms. Metabolic Brain Disease. 17: 375-87. PMID 12602514 DOI: 10.1023/A:1021970120965 |
0.475 |
|
| 2002 |
Zwingmann C, Desjardins P, Hazell A, Chatauret N, Michalak A, Butterworth RF. Reduced expression of astrocytic glycine transporter (Glyt-1) in acute liver failure. Metabolic Brain Disease. 17: 263-73. PMID 12602503 DOI: 10.1023/A:1021997532352 |
0.592 |
|
| 2002 |
Normandin L, Carrier G, Gardiner PF, Kennedy G, Hazell AS, Mergler D, Butterworth RF, Philippe S, Zayed J. Assessment of bioaccumulation, neuropathology, and neurobehavior following subchronic (90 days) inhalation in Sprague-Dawley rats exposed to manganese phosphate. Toxicology and Applied Pharmacology. 183: 135-45. PMID 12387753 DOI: 10.1006/Taap.2002.9464 |
0.523 |
|
| 2002 |
Hazell AS. Astrocytes and manganese neurotoxicity. Neurochemistry International. 41: 271-7. PMID 12106778 DOI: 10.1016/S0197-0186(02)00013-X |
0.475 |
|
| 2002 |
Sauvageau A, Desjardins P, Lozeva V, Rose C, Hazell AS, Bouthillier A, Butterwort RF. Increased expression of "peripheral-type" benzodiazepine receptors in human temporal lobe epilepsy: implications for PET imaging of hippocampal sclerosis. Metabolic Brain Disease. 17: 3-11. PMID 11893007 DOI: 10.1023/A:1014044128845 |
0.572 |
|
| 2001 |
Salehi F, Carrier G, Normandin L, Kennedy G, Butterworth RF, Hazell A, Therrien G, Mergler D, Philippe S, Zayed J. Assessment of bioaccumulation and neurotoxicity in rats with portacaval anastomosis and exposed to manganese phosphate: a pilot study. Inhalation Toxicology. 13: 1151-63. PMID 11696878 DOI: 10.1080/08958370152647654 |
0.496 |
|
| 2001 |
Ste-Marie L, Hazell AS, Bémeur C, Butterworth R, Montgomery J. Immunohistochemical detection of inducible nitric oxide synthase, nitrotyrosine and manganese superoxide dismutase following hyperglycemic focal cerebral ischemia. Brain Research. 918: 10-9. PMID 11684037 DOI: 10.1016/S0006-8993(01)02903-1 |
0.558 |
|
| 2001 |
Hazell AS, Rao KV, Danbolt NC, Pow DV, Butterworth RF. Selective down-regulation of the astrocyte glutamate transporters GLT-1 and GLAST within the medial thalamus in experimental Wernicke's encephalopathy. Journal of Neurochemistry. 78: 560-8. PMID 11483659 DOI: 10.1046/J.1471-4159.2001.00436.X |
0.623 |
|
| 2000 |
Pannunzio P, Hazell AS, Pannunzio M, Rao KV, Butterworth RF. Thiamine deficiency results in metabolic acidosis and energy failure in cerebellar granule cells: an in vitro model for the study of cell death mechanisms in Wernicke's encephalopathy. Journal of Neuroscience Research. 62: 286-92. PMID 11020221 DOI: 10.1002/1097-4547(20001015)62:2<286::Aid-Jnr13>3.0.Co;2-0 |
0.563 |
|
| 2000 |
Chan H, Hazell AS, Desjardins P, Butterworth RF. Effects of ammonia on glutamate transporter (GLAST) protein and mRNA in cultured rat cortical astrocytes. Neurochemistry International. 37: 243-8. PMID 10812209 DOI: 10.1016/S0197-0186(00)00026-7 |
0.627 |
|
| 1999 |
Todd KG, Hazell AS, Butterworth RF. Alcohol-thiamine interactions: an update on the pathogenesis of Wernicke encephalopathy. Addiction Biology. 4: 261-72. PMID 20575793 DOI: 10.1080/13556219971470 |
0.533 |
|
| 1999 |
Hazell AS, Butterworth RF. Hepatic encephalopathy: An update of pathophysiologic mechanisms. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 222: 99-112. PMID 10564534 DOI: 10.1046/J.1525-1373.1999.D01-120.X |
0.558 |
|
| 1999 |
Desjardins P, Todd KG, Hazell AS, Butterworth RF. Increased "peripheral-type" benzodiazepine receptor sites and mRNA in thalamus of thiamine-deficient rats. Neurochemistry International. 35: 363-9. PMID 10517697 DOI: 10.1016/S0197-0186(99)00082-0 |
0.581 |
|
| 1999 |
Hazell AS, Desjardins P, Butterworth RF. Chronic exposure of rat primary astrocyte cultures to manganese results in increased binding sites for the 'peripheral-type' benzodiazepine receptor ligand 3H-PK 11195. Neuroscience Letters. 271: 5-8. PMID 10471200 DOI: 10.1016/S0304-3940(99)00489-9 |
0.574 |
|
| 1999 |
Hazell AS, Desjardins P, Butterworth RF. Increased expression of glyceraldehyde-3-phosphate dehydrogenase in cultured astrocytes following exposure to manganese. Neurochemistry International. 35: 11-7. PMID 10403426 DOI: 10.1016/S0197-0186(99)00024-8 |
0.58 |
|
| 1998 |
Hazell AS, Todd KG, Butterworth RF. Mechanisms of neuronal cell death in Wernicke's encephalopathy. Metabolic Brain Disease. 13: 97-122. PMID 9699919 DOI: 10.1023/A:1020657129593 |
0.614 |
|
| 1998 |
Hazell AS, Norenberg MD. Ammonia and manganese increase arginine uptake in cultured astrocytes. Neurochemical Research. 23: 869-73. PMID 9572676 DOI: 10.1023/A:1022411012512 |
0.379 |
|
| 1998 |
Butterworth R, Desjardins P, Bandeira P, Hazell A. Altered “peripheral-type” benzodiazepine receptor (PTBR) gene expression in brain and testis following end-to-side portacaval anastomosis Journal of Hepatology. 28: 73. DOI: 10.1016/S0168-8278(98)80490-X |
0.463 |
|
| 1997 |
Hazell AS, Norenberg MD. Manganese decreases glutamate uptake in cultured astrocytes. Neurochemical Research. 22: 1443-7. PMID 9357008 DOI: 10.1023/A:1021994126329 |
0.43 |
|
| 1997 |
Hazell AS, Itzhak Y, Liu H, Norenberg MD. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) decreases glutamate uptake in cultured astrocytes. Journal of Neurochemistry. 68: 2216-9. PMID 9109551 DOI: 10.1046/J.1471-4159.1997.68052216.X |
0.434 |
|
| 1993 |
Hazell AS, Butterworth RF, Hakim AM. Cerebral vulnerability is associated with selective increase in extracellular glutamate concentration in experimental thiamine deficiency. Journal of Neurochemistry. 61: 1155-8. PMID 8103080 DOI: 10.1111/J.1471-4159.1993.Tb03635.X |
0.606 |
|
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