| Year |
Citation |
Score |
| 2024 |
Pidala JA, Holtan SG, Walton K, Kim J, Cao B, Elmariah H, Mishra A, Bejanyan N, Nishihori T, Khimani F, Perez LE, Faramand RG, Davila ML, McSain S, Pleskow J, ... ... Blazar BR, et al. JAK2/mTOR Inhibition Fails to Prevent Acute GVHD Despite Reduced Th1/Th17 cells: Final Phase II Trial Results. Blood. PMID 39046783 DOI: 10.1182/blood.2024024789 |
0.375 |
|
| 2024 |
Talvard-Balland N, Braun LM, Dixon KO, Zwick M, Engel H, Hartmann A, Duquesne S, Penter L, Andrieux G, Rindlisbacher LS, Acerbis A, Ehmann J, Köllerer C, Ansuinelli M, Rettig A, ... ... Blazar BR, et al. Oncogene induced TIM-3 ligand expression dictates susceptibility to anti-TIM-3 therapy in mice. The Journal of Clinical Investigation. PMID 38916965 DOI: 10.1172/JCI177460 |
0.368 |
|
| 2024 |
Schmidt D, Endres C, Hoefflin R, Andrieux G, Zwick M, Karantzelis N, Staehle HF, Vinnakota JM, Duquesne S, Mozaffari Jovein M, Pfeifer D, Becker H, Blazar BR, Zähringer A, Duyster J, et al. Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment. Cancer Research. PMID 38885318 DOI: 10.1158/0008-5472.CAN-23-3553 |
0.329 |
|
| 2024 |
Wang Y, Ullah MA, Waltner OG, Bhise SS, Ensbey KS, Schmidt CR, Legg SR, Sekiguchi T, Nelson EL, Kuns RD, Nemychenkov NS, Atilla E, Yeh AC, Takahashi S, Boiko JR, ... ... Blazar BR, et al. Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. The Journal of Clinical Investigation. 134. PMID 38828727 DOI: 10.1172/JCI170125 |
0.531 |
|
| 2024 |
Mazziotta F, Biavati L, Rimando JC, Rutella S, Borcherding N, Parbhoo S, Mukhopadhyay R, Knaus HA, Valent P, Hackl H, Borrello I, Blazar BR, Hatzi K, Gojo I, Luznik L. CD8+ T-cell Differentiation and Dysfunction Inform Treatment Response in Acute Myeloid Leukemia. Blood. PMID 38776511 DOI: 10.1182/blood.2023021680 |
0.375 |
|
| 2024 |
Steinbeck BJ, Gao XD, McElroy AN, Pandey S, Doman JL, Riddle MJ, Xia L, Chen W, Eide CR, Lengert AH, Han SW, Blazar BR, Wandall HH, Dabelsteen S, Liu DR, et al. Twin prime editing mediated exon skipping/reinsertion for restored collagen VII expression in recessive dystrophic epidermolysis bullosa. The Journal of Investigative Dermatology. PMID 38763174 DOI: 10.1016/j.jid.2024.04.013 |
0.572 |
|
| 2024 |
Vinnakota JM, Biavasco F, Schwabenland M, Chhatbar C, Adams RC, Erny D, Duquesne S, El Khawanky N, Schmidt D, Fetsch V, Zähringer A, Salié H, Athanassopoulos D, Braun LM, Javorniczky NR, ... ... Blazar BR, et al. Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nature Cancer. PMID 38741011 DOI: 10.1038/s43018-024-00764-7 |
0.398 |
|
| 2024 |
Saha A, Palchaudhuri R, Lanieri L, Hyzy S, Riddle MJ, Panthera J, Eide C, Tolar J, Panoskaltsis-Mortari A, Gorfinkel L, Tkachev V, Gerdemann U, Alvarez-Calderon F, Palato ER, MacMillan ML, ... ... Blazar BR, et al. Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice. Blood. PMID 38447038 DOI: 10.1182/blood.2023023549 |
0.691 |
|
| 2024 |
Arnhold V, Chang WY, Jansen SA, Thangavelu G, Calafiore M, Vinci P, Fu YY, Ito T, Takashima S, Egorova A, Kuttiyara J, Perlstein A, van Hoesel M, Liu C, Blazar BR, et al. Corticosteroids impair epithelial regeneration in immune-mediated intestinal damage. The Journal of Clinical Investigation. PMID 38349762 DOI: 10.1172/JCI155880 |
0.302 |
|
| 2024 |
Lineburg KE, Leveque-El Mouttie L, Hunter CR, Le Texier L, McGirr C, Teal B, Blazar BR, Lane SW, Hill GR, Levesque JP, MacDonald KPA. Autophagy prevents graft failure during murine Graft versus Host Disease. Blood Advances. PMID 38295282 DOI: 10.1182/bloodadvances.2023010972 |
0.385 |
|
| 2024 |
Maas-Bauer K, Stell AV, Yan KL, de Vega E, Vinnakota JM, Unger S, Núñez N, Norona J, Talvard-Balland N, Koßmann S, Schwan C, Miething C, Martens US, Shoumariyeh K, Nestor RP, ... ... Blazar BR, et al. ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature Communications. 15: 446. PMID 38199985 DOI: 10.1038/s41467-024-44703-7 |
0.403 |
|
| 2023 |
Braverman EL, McQuaid MA, Schuler H, Qin M, Hani S, Hippen K, Monlish DA, Dobbs AK, Ramsey MJ, Kemp F, Wittmann C, Ramgopal A, Brown H, Blazar B, Byersdorfer CA. Overexpression of AMPKγ2 increases AMPK signaling to augment human T cell metabolism and function. The Journal of Biological Chemistry. 105488. PMID 38000657 DOI: 10.1016/j.jbc.2023.105488 |
0.422 |
|
| 2023 |
Zhang H, Cavazzoni CB, Podestà MA, Bechu ED, Ralli G, Chandrakar P, Lee JM, Sayin I, Tullius SG, Abdi R, Chong AS, Blazar BR, Sage PT. IL-21-producing effector Tfh cells promote B cell alloimmunity in lymph nodes and kidney allografts. Jci Insight. 8. PMID 37870962 DOI: 10.1172/jci.insight.169793 |
0.432 |
|
| 2023 |
Le CT, Vick LV, Collins C, Dunai C, Sheng MK, Khuat LT, Barao I, Judge SJ, Aguilar EG, Curti B, Dave M, Longo DL, Blazar BR, Canter RJ, Monjazeb AM, et al. Regulation of human and mouse bystander T cell activation responses by PD-1. Jci Insight. 8. PMID 37737264 DOI: 10.1172/jci.insight.173287 |
0.316 |
|
| 2023 |
Tkachev V, Vanderbeck A, Perkey E, Furlan SN, McGuckin C, Gómez Atria D, Gerdemann U, Rui X, Lane J, Hunt DJ, Zheng H, Colonna L, Hoffman M, Yu A, Outen R, ... ... Blazar BR, et al. Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates. Science Translational Medicine. 15: eadd1175. PMID 37379368 DOI: 10.1126/scitranslmed.add1175 |
0.486 |
|
| 2023 |
Truscott J, Guan X, Fury H, Atagozli T, Metwali A, Liu W, Li Y, Li RW, Elliott DE, Blazar BR, Ince MN. After Bone Marrow Transplantation, the Cell-Intrinsic Th2 Pathway Promotes Recipient T Lymphocyte Survival and Regulates Graft-versus-Host Disease. Immunohorizons. 7: 442-455. PMID 37294277 DOI: 10.4049/immunohorizons.2300021 |
0.47 |
|
| 2023 |
Mohammadpour H, Tsuji T, MacDonald CR, Sarow JL, Rosenheck H, Daneshmandi S, Choi JE, Qiu J, Matsuzaki J, Witkiewicz AK, Attwood K, Blazar BR, Odunsi K, Repasky EA, McCarthy PL. Galectin-3 expression in donor T cells reduces GvHD severity and lethality after allogeneic hematopoietic cell transplantation. Cell Reports. 42: 112250. PMID 36924493 DOI: 10.1016/j.celrep.2023.112250 |
0.525 |
|
| 2023 |
Larson JH, Jin S, Loschi M, Wagers SB, Thangavelu G, Zaiken MC, McDonald-Hyman C, Saha A, Aguilar EG, Koehn B, Osborn MJ, Panoskaltsis-Mortari A, Macdonald KPA, Hill GR, Murphy WJ, ... ... Blazar BR, et al. Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 36878433 DOI: 10.1016/j.ajt.2023.01.030 |
0.724 |
|
| 2023 |
Holtan SG, Savid-Frontera C, Walton K, Eaton AA, Demorest C, Hoeschen A, Zhang L, Reid K, Kurian T, Sayegh Z, Julia E, Maakaron J, Bachanova V, El Jurdi N, MacMillan ML, ... ... Blazar BR, et al. Human effectors of acute and chronic GVHD overexpress CD83 and predict mortality. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36622700 DOI: 10.1158/1078-0432.CCR-22-2837 |
0.403 |
|
| 2022 |
Lopes Ramos T, Bolivar-Wagers S, Jin S, Thangavelu G, Simonetta F, Lin PY, Hirai T, Saha A, Koehn BH, L Su L, Picton LK, Baker J, Lohmeyer JK, Riddle MJ, Eide C, ... ... Blazar BR, et al. Prevention of acute GVHD disease using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T-cells in vivo. Blood. PMID 36564052 DOI: 10.1182/blood.2022018440 |
0.446 |
|
| 2022 |
Pennell CA, Campbell H, Storlie MD, Bolivar-Wagers S, Osborn MJ, Refaeli Y, Jensen M, Viaud S, Young TS, Blazar BR. Human CD19-specific switchable CAR T-cells are efficacious as constitutively active CAR T-cells but cause less morbidity in a mouse model of human CD19 malignancy. Journal For Immunotherapy of Cancer. 10. PMID 36521930 DOI: 10.1136/jitc-2022-005934 |
0.73 |
|
| 2022 |
Saha A, Blazar BR. Antibody based conditioning for allogeneic hematopoietic stem cell transplantation. Frontiers in Immunology. 13: 1031334. PMID 36341432 DOI: 10.3389/fimmu.2022.1031334 |
0.306 |
|
| 2022 |
Hippen KL, Hefazi M, Larson JH, Blazar BR. Emerging translational strategies and challenges for enhancing regulatory T cell therapy for graft-versus-host disease. Frontiers in Immunology. 13: 926550. PMID 35967386 DOI: 10.3389/fimmu.2022.926550 |
0.451 |
|
| 2022 |
Bolivar-Wagers S, Loschi ML, Jin S, Thangavelu G, Larson JH, McDonald-Hyman CS, Aguilar EA, Saha A, Koehn BH, Hefazi M, Osborn MJ, Jensen MC, Wagner JE, Pennell CA, Blazar BR. Murine CAR19 Tregs suppress acute graft-versus-host disease and maintain graft-versus-tumor responses. Jci Insight. PMID 35917188 DOI: 10.1172/jci.insight.160674 |
0.74 |
|
| 2022 |
Ho JG, Schmidt D, Lowinus T, Ryoo J, Dopfer EP, Gonzalo Nunez N, Costa-Pereira S, Toffalori C, Punta M, Fetsch V, Wertheimer T, Rittmann MC, Braun LM, Follo M, Briere C, ... ... Blazar BR, et al. Targeting MDM2 enhances anti-leukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood. PMID 35853161 DOI: 10.1182/blood.2022016082 |
0.421 |
|
| 2022 |
Thangavelu G, Andrejeva G, Bolivar-Wagers S, Jin S, Zaiken MC, Loschi M, Aguilar EG, Furlan SN, Brown CC, Lee YC, Hyman CM, Feser CJ, Panoskaltsis-Mortari A, Hippen KL, MacDonald KP, ... ... Blazar BR, et al. Retinoic acid signaling acts as a rheostat to balance Treg function. Cellular & Molecular Immunology. PMID 35581350 DOI: 10.1038/s41423-022-00869-y |
0.324 |
|
| 2022 |
Dwyer GK, Mathews LR, Villegas JA, Lucas A, Gonzalez de Peredo A, Blazar BR, Girard JP, Poholek AC, Luther SA, Shlomchik W, Turnquist HR. IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease. The Journal of Clinical Investigation. PMID 35503257 DOI: 10.1172/JCI150927 |
0.474 |
|
| 2022 |
Bolivar-Wagers S, Larson JH, Jin S, Blazar BR. Cytolytic CD4 and CD8 Regulatory T-Cells and Implications for Developing Immunotherapies to Combat Graft-Versus-Host Disease. Frontiers in Immunology. 13: 864748. PMID 35493508 DOI: 10.3389/fimmu.2022.864748 |
0.417 |
|
| 2022 |
Saxena V, Piao W, Li L, Paluskievicz C, Xiong Y, Simon T, Lakhan R, Brinkman CC, Walden S, Hippen KL, WillsonShirkey M, Lee YS, Wagner C, Blazar BR, Bromberg JS. Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses. Cell Reports. 39: 110727. PMID 35443187 DOI: 10.1016/j.celrep.2022.110727 |
0.361 |
|
| 2022 |
Thangavelu G, Zaiken MC, Mohamed FA, Flynn R, Du J, Rhee SY, Riddle MJ, Aguilar EG, Panoskaltsis-Mortari A, Sanders ME, Blazar BR. Targeting the Retinoid X Receptor Pathway Prevents and Ameliorates Murine Chronic Graft-Versus-Host Disease. Frontiers in Immunology. 13: 765319. PMID 35359939 DOI: 10.3389/fimmu.2022.765319 |
0.716 |
|
| 2022 |
Zaiken MC, Flynn R, Paz KG, Rhee SY, Jin S, Mohamed FA, Saha A, Thangavelu G, Park PMC, Hemming ML, Sage PT, Sharpe AH, DuPage M, Bluestone JA, Panoskaltsis-Mortari A, ... ... Blazar BR, et al. BET-bromodomain and EZH2 inhibitor treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes. Blood. PMID 35226736 DOI: 10.1182/blood.2021014557 |
0.705 |
|
| 2022 |
Saha A, Hyzy S, Lamothe TL, Hammond KJ, Clark NM, Lanieri L, Bhattarai PR, Palchaudhuri R, Gillard GO, Proctor J, Riddle MJ, Panoskaltsis-Mortari A, MacMillan ML, Wagner JE, Kiem HP, ... ... Blazar BR, et al. CD45-targeted antibody-drug-conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation. Blood. PMID 34986233 DOI: 10.1182/blood.2021012366 |
0.355 |
|
| 2021 |
Levy RB, Mousa HM, Lightbourn CO, Shiuey EJ, Latoni D, Duffort S, Flynn R, Du J, Barreras H, Zaiken M, Paz K, Blazar BR, Perez VL. Analyses and Correlation of Pathologic and Ocular Cutaneous Changes in Murine Graft versus Host Disease. International Journal of Molecular Sciences. 23. PMID 35008621 DOI: 10.3390/ijms23010184 |
0.669 |
|
| 2021 |
Chen X, MacNabb BW, Flood B, Blazar BR, Kline J. Divergent fates of antigen-specific CD8 T cell clones in mice with acute leukemia. Cell Reports. 37: 109991. PMID 34758311 DOI: 10.1016/j.celrep.2021.109991 |
0.405 |
|
| 2021 |
Knipping F, Newby GA, Eide CR, McElroy AN, Nielsen SC, Smith K, Fang Y, Cornu TI, Costa C, Gutierrez-Guerrero A, Bingea SP, Feser CJ, Steinbeck B, Hippen KL, Blazar BR, et al. Disruption of HIV-1 co-receptors CCR5 and CXCR4in primary human T cells and hematopoietic stemand progenitor cells using base editing. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34737067 DOI: 10.1016/j.ymthe.2021.10.026 |
0.676 |
|
| 2021 |
Mohamed FA, Thangavelu G, Rhee SY, Sage PT, O'Connor RS, Rathmell JC, Blazar BR. Recent Metabolic Advances for Preventing and Treating Acute and Chronic Graft Versus Host Disease. Frontiers in Immunology. 12: 757836. PMID 34712243 DOI: 10.3389/fimmu.2021.757836 |
0.45 |
|
| 2021 |
Ludwig LM, Hawley KM, Banks DB, Thomas-Toth AT, Blazar BR, McNerney ME, Leverson JD, LaBelle JL. Venetoclax imparts distinct cell death sensitivity and adaptivity patterns in T cells. Cell Death & Disease. 12: 1005. PMID 34707089 DOI: 10.1038/s41419-021-04285-4 |
0.305 |
|
| 2021 |
Walton K, Walker K, Riddle M, Koehn BH, Reff J, Sagatys EM, Linden MA, Pidala J, Kim J, Lee MC, Kiluk JV, Hui JYC, Yun SY, Xing Y, Stefanski H, ... ... Blazar BR, et al. Dual JAK2/Aurora kinase A inhibition prevents human skin graft rejection by allo-inactivation and ILC2-mediated tissue repair. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 34668635 DOI: 10.1111/ajt.16870 |
0.368 |
|
| 2021 |
Inoue T, Koyama M, Kaida K, Ikegame K, Ensbey KS, Samson L, Takahashi S, Zhang P, Minnie SA, Maruyama S, Ishii S, Daimon T, Fukuda T, Nakamae H, Ara T, ... ... Blazar BR, et al. Peri-transplant glucocorticoids redistribute donor T-cells to the bone marrow and prevent relapse after haploidentical SCT. Jci Insight. PMID 34637399 DOI: 10.1172/jci.insight.153551 |
0.426 |
|
| 2021 |
Nicholls J, Cao B, Le Texier L, Xiong LY, Hunter CR, Llanes G, Aguliar EG, Schroder WA, Phipps S, Lynch JP, Cao H, Heazlewood SY, Williams B, Clouston AD, Nefzger CM, ... ... Blazar BR, et al. Bone Marrow Regulatory T Cells Are a Unique Population, Supported by Niche-Specific Cytokines and Plasmacytoid Dendritic Cells, and Required for Chronic Graft-Versus-Host Disease Control. Frontiers in Cell and Developmental Biology. 9: 737880. PMID 34631716 DOI: 10.3389/fcell.2021.737880 |
0.425 |
|
| 2021 |
Bruce DW, Kolupaev OV, Laurie SJ, Bommiasamy H, Stefanski H, Blazar BR, Coghill J, Serody J. Third Party Type 2 Innate Lymphoid Cells Prevent and Treat GI Tract GvHD. Blood Advances. PMID 34619767 DOI: 10.1182/bloodadvances.2020001514 |
0.434 |
|
| 2021 |
DeFilipp Z, Hefazi M, Chen YB, Blazar BR. Emerging approaches to improve allogeneic hematopoietic cell transplantation outcomes for non-malignant diseases. Blood. PMID 34614174 DOI: 10.1182/blood.2020009014 |
0.317 |
|
| 2021 |
Hefazi M, Bolivar-Wagers S, Blazar BR. Regulatory T Cell Therapy of Graft-versus-Host Disease: Advances and Challenges. International Journal of Molecular Sciences. 22. PMID 34575843 DOI: 10.3390/ijms22189676 |
0.399 |
|
| 2021 |
Adams RC, Carter-Cusack D, Shaikh SN, Llanes GT, Johnston RL, Quaife-Ryan G, Boyle GM, Koufariotis LT, Möller A, Blazar BR, Vukovic J, MacDonald KP. Donor bone marrow-derived macrophage MHC II drives neuroinflammation and altered behaviour during chronic GVHD in mice. Blood. PMID 34570880 DOI: 10.1182/blood.2021011671 |
0.346 |
|
| 2021 |
Woan KV, Kim H, Bjordahl R, Davis ZB, Gaidarova S, Goulding J, Hancock B, Mahmood S, Abujarour R, Wang H, Tuininga K, Zhang B, Wu CY, Kodal B, Khaw M, ... ... Blazar BR, et al. Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy. Cell Stem Cell. PMID 34525347 DOI: 10.1016/j.stem.2021.08.013 |
0.355 |
|
| 2021 |
Aguilar EG, Dunai C, Judge SJ, Zamora AE, Khuat LT, Vick LV, Collins CP, Stoffel KM, Alvarez M, Barao I, Miller JS, Blazar BR, Chevallier P, Retière C, Canter RJ, et al. Activation Status Dictates the Function of Unlicensed Natural Killer Cells. Blood Advances. PMID 34496010 DOI: 10.1182/bloodadvances.2021004589 |
0.305 |
|
| 2021 |
Kramer A, Astuti Y, Elfstrum A, Lehrke MJ, Tolar J, Blazar BR, Blake A, Taisto M, Furcich JW, Nolan EE, Durose WW, Webber BR, Geisness A, Wood DK, Lund T. An irradiated marrow niche reveals a small non-collagenous protein mediator of homing, dermatopontin. Blood Advances. PMID 34448828 DOI: 10.1182/bloodadvances.2021004475 |
0.718 |
|
| 2021 |
Henden AS, Koyama M, Robb RJ, Forero A, Kuns RD, Chang K, Ensbey KS, Varelias A, Kazakoff SH, Waddell N, Clouston AD, Giri R, Begun J, Blazar BR, Degli-Esposti MA, et al. IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease. Blood. 138: 722-737. PMID 34436524 DOI: 10.1182/blood.2020006375 |
0.373 |
|
| 2021 |
Khuat LT, Vick LV, Dunai C, Collins CP, More SK, Le CT, Pai CS, Stoffel KM, Maverakis E, Canter RJ, Monjazeb AM, Longo DL, Abedi M, Choi E, Blazar BR, et al. Increased efficacy of dual pro-inflammatory cytokine blockade on acute GVHD while maintaining GVT effects. Blood. PMID 34424962 DOI: 10.1182/blood.2021011216 |
0.315 |
|
| 2021 |
Zanin-Zhorov A, Blazar BR. ROCK2, a critical regulator of immune modulation and fibrosis has emerged as a therapeutic target in chronic graft-versus-host disease. Clinical Immunology (Orlando, Fla.). 230: 108823. PMID 34400321 DOI: 10.1016/j.clim.2021.108823 |
0.336 |
|
| 2021 |
Monlish DA, Beezhold KJ, Chiaranunt P, Paz K, Moore NJ, Dobbs AK, Brown RA, Ozolek JA, Blazar BR, Byersdorfer CA. Deletion of AMPK minimizes graft-versus-host disease through an early impact on effector donor T cells. Jci Insight. 6. PMID 34291733 DOI: 10.1172/jci.insight.143811 |
0.49 |
|
| 2021 |
Henden AS, Koyama M, Robb RJ, Forero A, Kuns RD, Chang K, Ensbey KS, Varelias A, Kazakoff SH, Waddell N, Clouston AD, Giri R, Begun J, Blazar BR, Degli-Esposti MA, et al. IFNλ Therapy Prevents Severe Gastrointestinal Graft-versus-Host Disease. Blood. PMID 33951730 DOI: 10.1182/blood.2020006375 |
0.393 |
|
| 2021 |
Hippen KL, Furlan SN, Roychoudhuri R, Wang E, Zhang Y, Osborn MJ, Merkel SC, Hani S, MacMillan ML, Cichocki F, Miller JS, Wagner JE, Restifo NP, Kean LS, Blazar BR. Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion. Cytotherapy. PMID 33893050 DOI: 10.1016/j.jcyt.2021.02.118 |
0.739 |
|
| 2021 |
Pidala J, Walton K, Elmariah H, Kim J, Mishra A, Bejanyan N, Nishihori T, Khimani F, Perez L, Faramand RG, Davila ML, Nieder ML, Sagatys EM, Holtan SG, Lawrence NJ, ... ... Blazar BR, et al. Pacritinib combined with sirolimus and low-dose tacrolimus for GVHD prevention after allogeneic hematopoietic cell transplantation: Preclinical and Phase I trial results. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33753457 DOI: 10.1158/1078-0432.CCR-20-4725 |
0.374 |
|
| 2021 |
Osborn MJ, Bhardwaj A, Bingea SP, Knipping F, Feser CJ, Lees CJ, Collins DP, Steer CJ, Blazar BR, Tolar J. CRISPR/Cas9-Based Lateral Flow and Fluorescence Diagnostics. Bioengineering (Basel, Switzerland). 8. PMID 33673107 DOI: 10.3390/bioengineering8020023 |
0.545 |
|
| 2021 |
MacMillan ML, Hippen KL, McKenna DH, Kadidlo D, Sumstad D, DeFor TE, Brunstein CG, Holtan SG, Miller JS, Warlick ED, Weisdorf DJ, Wagner JE, Blazar BR. First-in-human phase 1 trial of induced regulatory T cells for graft-versus-host disease prophylaxis in HLA-matched siblings. Blood Advances. 5: 1425-1436. PMID 33666654 DOI: 10.1182/bloodadvances.2020003219 |
0.387 |
|
| 2021 |
Watkins B, Qayed M, McCracken C, Bratrude B, Betz K, Suessmuth Y, Yu A, Sinclair S, Furlan S, Bosinger S, Tkachev V, Rhodes J, Tumlin AG, Narayan A, Cribbin K, ... ... Blazar BR, et al. Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2001086. PMID 33449816 DOI: 10.1200/JCO.20.01086 |
0.322 |
|
| 2021 |
Tkachev V, Kaminski J, Potter EL, Furlan SN, Yu A, Hunt DJ, McGuckin C, Zheng H, Colonna L, Gerdemann U, Carlson J, Hoffman M, Olvera J, English C, Baldessari A, ... ... Blazar BR, et al. Spatiotemporal single-cell profiling reveals that invasive and tissue-resident memory donor CD8 T cells drive gastrointestinal acute graft-versus-host disease. Science Translational Medicine. 13. PMID 33441422 DOI: 10.1126/scitranslmed.abc0227 |
0.463 |
|
| 2021 |
Hill GR, Betts BC, Tkachev V, Kean LS, Blazar BR. Current Concepts and Advances in Graft-Versus-Host Disease Immunology. Annual Review of Immunology. PMID 33428454 DOI: 10.1146/annurev-immunol-102119-073227 |
0.332 |
|
| 2021 |
Mohammed MT, Cai S, Hanson BL, Zhang H, Clement RL, Daccache J, Cavazzoni CB, Blazar BR, Alessandrini A, Rennke HG, Chandraker A, Sage PT. Follicular T cells Mediate Donor Specific Antibody and Rejection after Solid Organ Transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 33421294 DOI: 10.1111/ajt.16484 |
0.399 |
|
| 2020 |
Ebelt ND, Zuniga E, Marzagalli M, Zamloot V, Blazar BR, Salgia R, Manuel ER. -Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy. Biomedicines. 8. PMID 33339195 DOI: 10.3390/biomedicines8120617 |
0.308 |
|
| 2020 |
Khuat LT, Le CT, Pai CS, Shields-Cutler RR, Holtan SG, Rashidi A, Parker SL, Knights D, Luna JI, Dunai C, Wang Z, Sturgill IR, Stoffel KM, Merleev AA, More SK, ... ... Blazar BR, et al. Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation. Science Translational Medicine. 12. PMID 33239390 DOI: 10.1126/scitranslmed.aay7713 |
0.33 |
|
| 2020 |
Almeida L, Dhillon-LaBrooy A, Castro CN, Adossa N, Carriche GM, Guderian M, Lippens S, Dennerlein S, Hesse C, Lambrecht BN, Berod L, Schauser L, Blazar BR, Kalesse M, Müller R, et al. Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis. Immunity. PMID 33238133 DOI: 10.1016/j.immuni.2020.11.001 |
0.365 |
|
| 2020 |
Cichocki F, Bjordahl R, Gaidarova S, Mahmood S, Abujarour R, Wang H, Tuininga K, Felices M, Davis ZB, Bendzick L, Clarke R, Stokely L, Rogers P, Ge M, Robinson M, ... ... Blazar BR, et al. iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy. Science Translational Medicine. 12. PMID 33148626 DOI: 10.1126/scitranslmed.aaz5618 |
0.337 |
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| 2020 |
Ding ZC, Shi H, Aboelella NS, Fesenkova K, Park EJ, Liu Z, Pei L, Li J, McIndoe RA, Xu H, Piazza GA, Blazar BR, Munn DH, Zhou G. Persistent STAT5 activation reprograms the epigenetic landscape in CD4 T cells to drive polyfunctionality and antitumor immunity. Science Immunology. 5. PMID 33127608 DOI: 10.1126/sciimmunol.aba5962 |
0.392 |
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| 2020 |
Uhl FM, Chen S, O'Sullivan D, Edwards-Hicks J, Richter G, Haring E, Andrieux G, Halbach S, Apostolova P, Büscher J, Duquesne S, Melchinger W, Sauer B, Shoumariyeh K, Schmitt-Graeff A, ... ... Blazar BR, et al. Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans. Science Translational Medicine. 12. PMID 33115954 DOI: 10.1126/scitranslmed.abb8969 |
0.41 |
|
| 2020 |
Arvindam US, van Hauten PMM, Schirm D, Schaap N, Hobo W, Blazar BR, Vallera DA, Dolstra H, Felices M, Miller JS. A trispecific killer engager molecule against CLEC12A effectively induces NK-cell mediated killing of AML cells. Leukemia. PMID 33097838 DOI: 10.1038/s41375-020-01065-5 |
0.363 |
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| 2020 |
Adom D, Dillon SR, Yang J, Liu H, Ramadan A, Kushekhar K, Hund S, Albright A, Kirksey M, Adeniyan T, Lewis KE, Evans L, Wu R, Levin SD, Mudri S, ... ... Blazar BR, et al. ICOSL plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist. Science Translational Medicine. 12. PMID 33028709 DOI: 10.1126/scitranslmed.aay4799 |
0.475 |
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| 2020 |
Thangavelu G, Wang C, Loschi M, Saha A, Osborn M, Furlan SN, Aoyama K, McDonald-Hyman C, Aguilar EG, Janesick AS, Chandraratna RA, Refaeli Y, Panoskaltsis-Mortari A, MacDonald KP, Hill GR, ... ... Blazar BR, et al. Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses. Blood. PMID 32976550 DOI: 10.1182/blood.2020005628 |
0.742 |
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| 2020 |
Zheng P, Tamaresis J, Thangavelu G, Xu L, You X, Blazar BR, Negrin RS, Zehnder JL, Iliopoulou BP, Meyer EH. Recipient-specific T-cell repertoire reconstitution in the gut following murine hematopoietic cell transplant. Blood Advances. 4: 4232-4243. PMID 32898248 DOI: 10.1182/Bloodadvances.2019000977 |
0.531 |
|
| 2020 |
Bader CS, Barreras H, Lightbourn CO, Copsel SN, Wolf D, Meng J, Ahn J, Komanduri KV, Blazar BR, Jin L, Barber GN, Roy S, Levy RB. STING differentially regulates experimental GVHD mediated by CD8 versus CD4 T cell subsets. Science Translational Medicine. 12. PMID 32669421 DOI: 10.1126/Scitranslmed.Aay5006 |
0.553 |
|
| 2020 |
Norona J, Apostolova P, Schmidt D, Ihlemann R, Reischmann N, Taylor G, Köhler N, de Heer J, Heeg S, Andrieux G, Siranosian BA, Schmitt-Graeff A, Pfeifer D, Catalano A, Frew I, ... ... Blazar BR, et al. Glucagon like peptide-2 for Intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans. Blood. PMID 32542357 DOI: 10.1182/Blood.2020005957 |
0.467 |
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| 2020 |
Ustun C, DeFor TE, Karadag FK, Don Yun H, Nathan S, Brunstein CG, Blazar BR, Weisdorf DJ, Holtan SG, Amin K. Tissue mast cell counts may be associated with decreased severity of gastrointestinal acute GVHD and nonrelapse mortality. Blood Advances. 4: 2317-2324. PMID 32453837 DOI: 10.1182/Bloodadvances.2020001793 |
0.481 |
|
| 2020 |
Mohammadpour H, Sarow JL, MacDonald CR, Chen GL, Qiu J, Sharma UC, Cao X, Herr MM, Hahn TE, Blazar BR, Repasky EA, McCarthy PL. β2-adrenergic receptor activation on donor cells ameliorates acute GvHD. Jci Insight. PMID 32437333 DOI: 10.1172/Jci.Insight.137788 |
0.506 |
|
| 2020 |
Shrestha B, Walton K, Reff J, Sagatys EM, Tu N, Boucher JC, Li G, Ghafoor T, Felices M, Miller J, Pidala J, Blazar BR, Anasetti C, Betts BC, Davila ML. Human CD83-targeted chimeric antigen receptor T cells prevent and treat graft-versus-host disease. The Journal of Clinical Investigation. PMID 32437331 DOI: 10.1172/Jci135754 |
0.526 |
|
| 2020 |
Blazar BR, Hill GR, Murphy WJ. Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD. Nature Reviews. Clinical Oncology. PMID 32313224 DOI: 10.1038/S41571-020-0356-4 |
0.444 |
|
| 2020 |
Furlan SN, Singh K, Lopez C, Tkachev V, Hunt DJ, Hibbard J, Betz KM, Blazar BR, Trapnell C, Kean LS. IL-2 enhances ex vivo-expanded regulatory T-cell persistence after adoptive transfer. Blood Advances. 4: 1594-1605. PMID 32311015 DOI: 10.1182/Bloodadvances.2019001248 |
0.482 |
|
| 2020 |
Walton K, Fernandez MR, Sagatys EM, Reff J, Kim J, Lee MC, Kiluk J, Hui JYC, McKenna D, Hupp M, Forster C, Linden MA, Lawrence NJ, Lawrence HR, Pidala J, ... ... Blazar BR, et al. Metabolic reprogramming augments potency of human pSTAT3-inhibited iTregs to suppress alloreactivity. Jci Insight. PMID 32255769 DOI: 10.1172/Jci.Insight.136437 |
0.505 |
|
| 2020 |
Hamarsheh S, Osswald L, Saller BS, Unger S, De Feo D, Vinnakota JM, Konantz M, Uhl FM, Becker H, Lübbert M, Shoumariyeh K, Schürch C, Andrieux G, Venhoff N, Schmitt-Graeff A, ... ... Blazar BR, et al. Oncogenic Kras causes myeloproliferation via NLRP3 inflammasome activation. Nature Communications. 11: 1659. PMID 32246016 DOI: 10.1038/S41467-020-15497-1 |
0.364 |
|
| 2020 |
Holtan SG, Hoeschen AL, Cao Q, Arora M, Bachanova V, Brunstein CG, Miller JS, Rashidi A, Slungaard A, Ustun C, Vercellotti GM, Warlick ED, Betts BC, El Jurdi N, He F, ... ... Blazar BR, et al. Facilitating resolution of life-threatening acute GVHD with human chorionic gonadotropin and epidermal growth factor. Blood Advances. 4: 1284-1295. PMID 32236525 DOI: 10.1182/Bloodadvances.2019001259 |
0.388 |
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| 2020 |
Srikanthan MA, Humbert O, Haworth KG, Ironside C, Rajawat YS, Blazar BR, Palchaudhuri R, Boitano AE, Cooke MP, Scadden DT, Kiem HP. Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning. Molecular Therapy. Methods & Clinical Development. 17: 455-464. PMID 32226796 DOI: 10.1016/J.Omtm.2020.02.001 |
0.478 |
|
| 2020 |
Judge SJ, Dunai C, Aguilar EG, Vick SC, Sturgill IR, Khuat LT, Stoffel KM, Van Dyke J, Longo DL, Darrow MA, Anderson SK, Blazar BR, Monjazeb AM, Serody JS, Canter RJ, et al. Minimal PD-1 expression in mouse and human NK cells under diverse conditions. The Journal of Clinical Investigation. PMID 32134744 DOI: 10.1172/Jci133353 |
0.416 |
|
| 2020 |
Le HT, Keslar K, Nguyen QT, Blazar BR, Hamilton BK, Min B. Interleukin-27 Enforces Regulatory T Cell Functions to Prevent Graft-versus-Host Disease. Frontiers in Immunology. 11: 181. PMID 32117306 DOI: 10.3389/Fimmu.2020.00181 |
0.505 |
|
| 2020 |
Rashidi A, Herman A, Gomes ALC, Peled JU, Jenq RR, Brereton DG, Staley C, Blazar BR, Weisdorf DJ. An alpha-defensin gene single nucleotide polymorphism modulates the gut microbiota and may alter the risk of acute graft-versus-host disease. British Journal of Haematology. PMID 32086815 DOI: 10.1111/Bjh.16458 |
0.347 |
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| 2020 |
Zanin-Zhorov A, Kumari S, Hippen KL, Merkel SC, MacMillan ML, Blazar BR, Dustin ML. Author Correction: Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity. Scientific Reports. 10: 3317. PMID 32076101 DOI: 10.1038/S41598-020-60485-6 |
0.394 |
|
| 2020 |
Perkey E, Maurice De Sousa D, Carrington L, Chung J, Dils A, Granadier D, Koch U, Radtke F, Ludewig B, Blazar BR, Siebel CW, Brennan TV, Nolz J, Labrecque N, Maillard I. GCNT1-Mediated -Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 32060138 DOI: 10.4049/Jimmunol.1901194 |
0.535 |
|
| 2020 |
Sarhan D, Wang J, Sunil Arvindam U, Hallstrom C, Verneris MR, Grzywacz B, Warlick E, Blazar BR, Miller JS. Mesenchymal stromal cells shape the MDS microenvironment by inducing suppressive monocytes that dampen NK cell function. Jci Insight. PMID 32045384 DOI: 10.1172/Jci.Insight.130155 |
0.419 |
|
| 2020 |
Li L, Shirkey MW, Zhang T, Xiong Y, Piao W, Saxena V, Paluskievicz C, Lee YS, Toney N, Cerel BM, Li Q, Simon T, Smith KD, Hippen KL, Blazar BR, et al. The lymph node stromal laminin alpha 5 shapes alloimmunity. The Journal of Clinical Investigation. PMID 32017712 DOI: 10.1172/Jci135099 |
0.523 |
|
| 2020 |
Piao W, Xiong Y, Li L, Saxena V, Smith KD, Hippen KL, Paluskievicz C, Willsonshirkey M, Blazar BR, Abdi R, Bromberg JS. Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration. Cell Reports. 30: 1052-1062.e5. PMID 31995749 DOI: 10.1016/J.Celrep.2019.12.083 |
0.394 |
|
| 2020 |
ElTanbouly MA, Zhao Y, Nowak E, Li J, Schaafsma E, Le Mercier I, Ceeraz S, Lines JL, Peng C, Carriere C, Huang X, Day M, Koehn B, Lee SW, Silva Morales M, ... ... Blazar BR, et al. VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance. Science (New York, N.Y.). 367. PMID 31949051 DOI: 10.1126/Science.Aay0524 |
0.488 |
|
| 2020 |
Truscott J, Guan X, Elliott DE, Blazar BR, Ince MN. Tu1250 INTESTINAL HELMINTHS PROMOTE ALLOTOLERANCE AND REGULATE COLITIS ASSOCIATED WITH GRAFT-VERSUS-HOST DISEASE THROUGH T HELPER-2/TGFβ-DEPENDENT GENERATION OF MIXED CHIMERISM Gastroenterology. 158: S-1033. DOI: 10.1016/S0016-5085(20)33260-1 |
0.42 |
|
| 2020 |
Hyzy SL, Palchaudhuri R, Proctor JL, Pearse BR, Sarma GN, Gillard GO, Saha A, Lamothe TL, Brooks ML, Hammond K, Bhat A, Clark N, McDonagh CF, Kiem H, Wagner JE, ... Blazar BR, et al. Successful Allogeneic Hematopoietic Stem Cell Transplantation in Mice Mediated By Well-Tolerated Conditioning Regimens Based on CD45-Targeted Antibody Drug Conjugate: Implications for Haplo Transplantation Biology of Blood and Marrow Transplantation. 26: S160. DOI: 10.1016/J.Bbmt.2019.12.713 |
0.483 |
|
| 2020 |
Hirai T, Simonetta F, Su LL, Picton L, Baker J, Seo K, Lohmeyer JK, Mavers M, Blazar BR, Garcia C, Negrin RS. Engineered IL-2 Cytokine-Cytokine Receptor Complex Enables Selective Expansion of Regulatory T Cells and Facilitates Establishment of Organ Transplantation Tolerance Biology of Blood and Marrow Transplantation. 26: S59-S60. DOI: 10.1016/J.Bbmt.2019.12.226 |
0.514 |
|
| 2020 |
Wagner JE, Brunstein CG, McKenna DH, Sumstad D, Miller JS, Blazar BR, Defor TE, Boitano AE, Cooke MP, Raffel GD, Davis JC, Stefanski H. Mgta-456, a Cell Therapy Utilizing Expansion of CD34+ Hematopoietic Stem Cells (HSC), Improves HLA Matching for Adult Recipients, Promotes Faster Hematopoietic Recovery and Enables Uniform Engraftment with Less Acute Graft-Vs-Host Disease (GVHD) Biology of Blood and Marrow Transplantation. 26: S205-S206. DOI: 10.1016/J.Bbmt.2019.12.222 |
0.461 |
|
| 2020 |
Bader CS, Barreras H, Lightbourn CO, Copsel SN, Wolf D, Meng J, Ahn J, Komanduri KV, Blazar BR, Jin L, Barber GN, Roy S, Levy RB. The Innate Immune Sensor Sting Promotes Donor CD8+ T Cell Activation and Recipient APC Death Early after Preclinical Allogeneic Hematopoietic Stem Cell Transplantation Biology of Blood and Marrow Transplantation. 26: S29. DOI: 10.1016/j.bbmt.2019.12.099 |
0.401 |
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| 2020 |
Walton K, Fernandez MR, Sagatys EM, Reff J, Kim J, Lee MC, Kiluk JV, Lawrence NJ, Lawrence HR, Pidala JA, Pavletic SZ, Blazar BR, Sebti SM, Cleveland JL, Anasetti C, et al. Human pSTAT3-Inhibited Itregs Prevent Gvhd, Maintain Anti-Leukemia Immunity, and Increase Their Potency after Metabolic Reprogramming Biology of Blood and Marrow Transplantation. 26: S164-S165. DOI: 10.1016/J.Bbmt.2019.12.023 |
0.481 |
|
| 2019 |
Field CS, Baixauli F, Kyle RL, Puleston DJ, Cameron AM, Sanin DE, Hippen KL, Loschi M, Thangavelu G, Corrado M, Edwards-Hicks J, Grzes KM, Pearce EJ, Blazar BR, Pearce EL. Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function. Cell Metabolism. PMID 31883840 DOI: 10.1016/J.Cmet.2019.11.021 |
0.372 |
|
| 2019 |
R Mathew N, Vinnakota JM, Apostolova P, Erny D, Hamarsheh S, Andrieux G, Kim JS, Hanke K, Goldmann T, Chappell-Maor L, El-Khawanky N, Ihorst G, Schmidt D, Duyster J, Finke J, ... ... Blazar BR, et al. Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia. The Journal of Clinical Investigation. PMID 31846439 DOI: 10.1172/Jci130272 |
0.445 |
|
| 2019 |
MacDonald KN, Ivison S, Hippen KL, Hoeppli RE, Hall M, Zheng G, Dijke IE, Aklabi MA, Freed DH, Rebeyka I, Gandhi S, West LJ, Piret JM, Blazar BR, Levings MK. Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol. Cytotherapy. PMID 31810768 DOI: 10.1016/J.Jcyt.2019.10.011 |
0.444 |
|
| 2019 |
Hippen KL, Aguilar EG, Rhee SY, Bolivar-Wagers S, Blazar BR. Distinct Regulatory and Effector T Cell Metabolic Demands during Graft-Versus-Host Disease. Trends in Immunology. PMID 31791718 DOI: 10.1016/J.It.2019.11.005 |
0.535 |
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| 2019 |
Newell LF, DeFor TE, Cutler C, Verneris MR, Blazar BR, Miller JS, Antin JH, Howard A, Wu J, MacMillan ML, Panoskaltsis-Mortari A, Weisdorf DJ, Holtan SG. Follistatin and Soluble Endoglin Predict 1-year Non-Relapse Mortality after Allogeneic Hematopoietic Cell Transplant. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 31715306 DOI: 10.1016/J.Bbmt.2019.11.006 |
0.38 |
|
| 2019 |
Thangavelu G, Du J, Paz KG, Loschi M, Zaiken MC, Flynn R, Taylor PA, Kirchmeier AK, Panoskaltsis-Mortari A, Luznik L, MacDonald KP, Hill GR, Maillard I, Munn DH, Serody JS, ... ... Blazar BR, et al. Inhibition of Inositol kinase B controls acute and chronic graft-versus-host disease. Blood. PMID 31697815 DOI: 10.1182/Blood.2019000032 |
0.758 |
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| 2019 |
Singh J, Chen ELY, Xing Y, Stefanski HE, Blazar BR, Zúñiga-Pflücker JC. Generation and function of progenitor T cells from StemRegenin-1-expanded CD34+ human hematopoietic progenitor cells. Blood Advances. 3: 2934-2948. PMID 31648315 DOI: 10.1182/Bloodadvances.2018026575 |
0.563 |
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| 2019 |
Saha A, Taylor PA, Lees CJ, Panoskaltsis-Mortari A, Osborn MJ, Feser CJ, Thangavelu G, Melchinger W, Refaeli Y, Hill GR, Munn DH, Murphy WJ, Serody JS, Maillard I, Kreymborg K, ... ... Blazar BR, et al. Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality. Jci Insight. 4. PMID 31578305 DOI: 10.1172/Jci.Insight.127716 |
0.728 |
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| 2019 |
Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, ... ... Blazar BR, et al. Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GvHD. Blood. PMID 31533918 DOI: 10.1182/Blood.2019001950 |
0.413 |
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| 2019 |
Clement RL, Daccache J, Mohammed MT, Diallo A, Blazar BR, Kuchroo VK, Lovitch SB, Sharpe AH, Sage PT. Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses. Nature Immunology. PMID 31477921 DOI: 10.1038/S41590-019-0472-4 |
0.485 |
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| 2019 |
MacMillan ML, Holtan SG, Rashidi A, DeFor TE, Blazar BR, Weisdorf DJ. Pediatric acute GVHD: clinical phenotype and response to upfront steroids. Bone Marrow Transplantation. PMID 31477785 DOI: 10.1038/S41409-019-0651-9 |
0.348 |
|
| 2019 |
Whangbo JS, Kim HT, Mirkovic N, Leonard L, Poryanda S, Silverstein S, Kim S, Reynolds CG, Rai SC, Verrill K, Lee MA, Margossian S, Duncan C, Lehmann L, Huang J, ... ... Blazar BR, et al. Dose-escalated interleukin-2 therapy for refractory chronic graft-versus-host disease in adults and children. Blood Advances. 3: 2550-2561. PMID 31471324 DOI: 10.1182/Bloodadvances.2019000631 |
0.379 |
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| 2019 |
Osborn MJ, Newby GA, McElroy AN, Knipping F, Nielsen SC, Riddle MJ, Xia L, Chen W, Eide CR, Webber BR, Wandall HH, Dabelsteen S, Blazar BR, Liu DR, Tolar J. Base editor correction of COL7A1 in recessive dystrophic epidermolysis bullosa patient-derived fibroblasts and iPSCs. The Journal of Investigative Dermatology. PMID 31437443 DOI: 10.1016/J.Jid.2019.07.701 |
0.781 |
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| 2019 |
Rashidi A, Ebadi M, Shields-Cutler RR, Kruziki K, Manias DA, Barnes AMT, DeFor TE, Ferrieri P, Young JH, Knights D, Blazar BR, Weisdorf DJ, Dunny GM. Early E. casseliflavus gut colonization and outcomes of allogeneic hematopoietic cell transplantation. Plos One. 14: e0220850. PMID 31393924 DOI: 10.1371/Journal.Pone.0220850 |
0.35 |
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| 2019 |
Holtan SG, Shabaneh A, Betts BC, Rashidi A, MacMillan ML, Ustun C, Amin K, Vaughn BP, Howard J, Khoruts A, Arora M, DeFor TE, Johnson D, Blazar BR, Weisdorf DJ, et al. Stress responses, M2 macrophages, and a distinct microbial signature in fatal intestinal acute graft-versus-host disease. Jci Insight. 5. PMID 31393854 DOI: 10.1172/Jci.Insight.129762 |
0.413 |
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| 2019 |
Paczulla AM, Rothfelder K, Raffel S, Konantz M, Steinbacher J, Wang H, Tandler C, Mbarga M, Schaefer T, Falcone M, Nievergall E, Dörfel D, Hanns P, Passweg JR, Lutz C, ... ... Blazar BR, et al. Publisher Correction: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion. Nature. PMID 31367045 DOI: 10.1038/S41586-019-1475-X |
0.341 |
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| 2019 |
Simon T, Li L, Wagner C, Zhang T, Saxena V, Brinkman CC, Tostanoski LH, Ostrand-Rosenberg S, Jewell C, Shea-Donohue T, Hippen K, Blazar B, Abdi R, Bromberg JS. Differential Regulation of T Cell Immunity and Tolerance by Stromal Laminin Expressed in the Lymph Node. Transplantation. PMID 31343575 DOI: 10.1097/Tp.0000000000002774 |
0.463 |
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| 2019 |
Rashidi A, DeFor TE, Holtan SG, Blazar BR, Weisdorf DJ, MacMillan ML. Outcomes and Predictors of Response in Steroid-Refractory Acute Graft-versus-Host Disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 31325587 DOI: 10.1016/J.Bbmt.2019.07.017 |
0.332 |
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| 2019 |
MacMillan ML, DeFor TE, Holtan SG, Rashidi A, Blazar BR, Weisdorf DJ. Validation of Minnesota acute graft-versus-host disease Risk Score. Haematologica. PMID 31320554 DOI: 10.3324/Haematol.2019.220970 |
0.338 |
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| 2019 |
Paczulla AM, Rothfelder K, Raffel S, Konantz M, Steinbacher J, Wang H, Tandler C, Mbarga M, Schaefer T, Falcone M, Nievergall E, Dörfel D, Hanns P, Passweg JR, Lutz C, ... ... Blazar BR, et al. Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion. Nature. PMID 31316209 DOI: 10.1038/S41586-019-1410-1 |
0.486 |
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| 2019 |
Cooley S, He F, Bachanova V, Vercellotti GM, DeFor TE, Curtsinger JM, Robertson P, Grzywacz B, Conlon KC, Waldmann TA, McKenna DH, Blazar BR, Weisdorf DJ, Miller JS. First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia. Blood Advances. 3: 1970-1980. PMID 31266741 DOI: 10.1182/Bloodadvances.2018028332 |
0.396 |
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| 2019 |
Sinha RK, Flynn R, Zaiken M, Paz K, Gavin AL, Nemazee D, Fernández JA, Xu X, Griffin JH, Blazar BR. Activated Protein C Ameliorates Chronic Graft-Versus-Host Disease by PAR1-dependent Biased Cell Signaling on T-cells. Blood. PMID 31243040 DOI: 10.1182/Blood.2019001259 |
0.732 |
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| 2019 |
Merino AM, Zhang B, Dougherty PR, Luo X, Wang J, Blazar BR, Miller JS, Cichocki F. Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming. The Journal of Clinical Investigation. 130. PMID 31211698 DOI: 10.1172/Jci125916 |
0.445 |
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| 2019 |
Chung J, Radojcic V, Perkey E, Parnell TJ, Niknafs Y, Jin X, Friedman A, Labrecque N, Blazar BR, Brennan TV, Siebel CW, Maillard I. Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4 T Cells in Graft-versus-Host Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 31182480 DOI: 10.4049/Jimmunol.1900192 |
0.572 |
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| 2019 |
Tanimine N, Germana SK, Fan M, Hippen K, Blazar BR, Markmann JF, Turka LA, Priyadharshini B. Differential effects of 2-deoxy-D-glucose on in vitro expanded human regulatory T cell subsets. Plos One. 14: e0217761. PMID 31170216 DOI: 10.1371/Journal.Pone.0217761 |
0.502 |
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| 2019 |
Holtan SG, Zhang L, DeFor TE, Bejanyan N, Arora M, Rashidi A, Lazaryan A, Kotiso F, Blazar BR, Wagner JE, Brunstein CG, MacMillan ML, Weisdorf DJ. Dynamic graft-versus-host disease-free, relapse-free survival (dGRFS): Multistate modeling of the morbidity and mortality of allotransplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 31128328 DOI: 10.1016/J.Bbmt.2019.05.015 |
0.375 |
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| 2019 |
Leung WH, Gay J, Martin U, Garrett TE, Horton HM, Certo MT, Blazar BR, Morgan RA, Gregory PD, Jarjour J, Astrakhan A. Sensitive and adaptable pharmacological control of CAR T cells through extracellular receptor dimerization. Jci Insight. 5. PMID 31039141 DOI: 10.1172/Jci.Insight.124430 |
0.398 |
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| 2019 |
Belizaire R, Kim HT, Poryanda SJ, Mirkovic NV, Hipolito E, Savage WJ, Reynolds CG, Fields MJ, Whangbo J, Kubo T, Nikiforow S, Alyea EP, Armand P, Cutler CS, Ho VT, ... Blazar BR, et al. Efficacy and immunologic effects of extracorporeal photopheresis plus interleukin-2 in chronic graft-versus-host disease. Blood Advances. 3: 969-979. PMID 30936057 DOI: 10.1182/Bloodadvances.2018029124 |
0.532 |
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| 2019 |
Thangavelu G, Blazar BR. Achievement of Tolerance Induction to Prevent Acute Graft-vs.-Host Disease. Frontiers in Immunology. 10: 309. PMID 30906290 DOI: 10.3389/Fimmu.2019.00309 |
0.422 |
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| 2019 |
Ni X, Kou W, Gu J, Wei P, Wu X, Peng H, Tao J, Yan W, Yang X, Lebid A, Park BV, Chen Z, Tian Y, Fu J, Newman S, ... ... Blazar BR, et al. TRAF6 directs FOXP3 localization and facilitates regulatory T-cell function through K63-linked ubiquitination. The Embo Journal. PMID 30886050 DOI: 10.15252/Embj.201899766 |
0.38 |
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| 2019 |
Thangavelu G, Lee YC, Loschi M, Schaechter KM, Feser CJ, Koehn BH, Nowak EC, Zeiser R, Serody JS, Murphy WJ, Munn DH, Chambon P, Noelle RJ, Blazar BR. Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality. Journal of Immunology (Baltimore, Md. : 1950). PMID 30885956 DOI: 10.4049/Jimmunol.1800899 |
0.46 |
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| 2019 |
Xiong Y, Piao W, Brinkman CC, Li L, Kulinski JM, Olivera A, Cartier A, Hla T, Hippen KL, Blazar BR, Schwab SR, Bromberg JS. CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration. Science Immunology. 4. PMID 30877143 DOI: 10.1126/Sciimmunol.Aav1263 |
0.46 |
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| 2019 |
Boroughs AC, Larson RC, Choi BD, Bouffard AA, Riley LS, Schiferle E, Kulkarni AS, Cetrulo CL, Ting D, Blazar BR, Demehri S, Maus MV. Chimeric antigen receptor costimulation domains modulate human regulatory T cell function. Jci Insight. 5. PMID 30869654 DOI: 10.1172/Jci.Insight.126194 |
0.495 |
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| 2019 |
Phan T, Nguyen VH, D'Alincourt MS, Manuel ER, Kaltcheva T, Tsai W, Blazar BR, Diamond DJ, Melstrom LG. Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth. Cancer Gene Therapy. PMID 30824815 DOI: 10.1038/S41417-019-0089-7 |
0.327 |
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| 2019 |
Paz K, Flynn R, Du J, Tannheimer S, Johnson AJ, Dong S, Stark AK, Okkenhaug K, Panoskaltsis-Mortari A, Sage PT, Sharpe AH, Luznik L, Ritz J, Soiffer RJ, Cutler CS, ... ... Blazar BR, et al. Targeting PI3Kδ Function For Amelioration of Murine Chronic Graft-Versus-Host Disease. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30748099 DOI: 10.1111/Ajt.15305 |
0.78 |
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| 2019 |
Rosato PC, Wijeyesinghe S, Stolley JM, Nelson CE, Davis RL, Manlove LS, Pennell CA, Blazar BR, Chen CC, Geller MA, Vezys V, Masopust D. Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy. Nature Communications. 10: 567. PMID 30718505 DOI: 10.1038/S41467-019-08534-1 |
0.391 |
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| 2019 |
Hou S, Clement RL, Diallo A, Blazar BR, Rudensky AY, Sharpe AH, Sage PT. FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program. The Journal of Experimental Medicine. PMID 30705058 DOI: 10.1084/Jem.20181134 |
0.373 |
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| 2019 |
Yang J, Ramadan A, Reichenbach DK, Loschi M, Zhang J, Griesenauer B, Liu H, Hippen KL, Blazar BR, Paczesny S. Rorc restrains the potency of ST2+ regulatory T cells in ameliorating intestinal graft-versus-host disease. Jci Insight. PMID 30694220 DOI: 10.1172/Jci.Insight.122014 |
0.544 |
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| 2019 |
Cichocki F, Taras E, Chiuppesi F, Wagner JE, Blazar BR, Brunstein C, Luo X, Diamond DJ, Cooley S, Weisdorf DJ, Miller JS. Adaptive NK cell reconstitution is associated with better clinical outcomes. Jci Insight. 4. PMID 30674718 DOI: 10.1172/Jci.Insight.125553 |
0.41 |
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| 2019 |
Liu B, Salgado OC, Singh S, Hippen KL, Maynard JC, Burlingame AL, Ball LE, Blazar BR, Farrar MA, Hogquist KA, Ruan HB. The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation. Nature Communications. 10: 354. PMID 30664665 DOI: 10.1038/S41467-019-08300-3 |
0.434 |
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| 2019 |
Paul J, Nakasone H, Sahaf B, Wu F, Wang K, Ho V, Wu J, Kim H, Blazar BR, Ritz J, Howard A, Cutler C, Miklos D. A confirmation of chronic graft-versus-host disease prediction using allogeneic HY antibodies following sex-mismatched hematopoietic cell transplantation. Haematologica. PMID 30655371 DOI: 10.3324/Haematol.2018.199646 |
0.42 |
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| 2019 |
Turcotte LM, Cao Q, Cooley SA, Curtsinger J, Holtan SG, Luo X, Yingst A, Weisdorf DJ, Blazar BR, Miller JS, Wagner JE, Verneris MR. Monocyte subpopulation recovery as predictors of hematopoietic cell transplantation outcomes. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 30625388 DOI: 10.1016/J.Bbmt.2019.01.003 |
0.402 |
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| 2019 |
Ni X, Xia Y, Zhou S, Peng H, Wu X, Lu H, Wang H, Liu R, Blazar BR, Gu J, Lu L. Reduction in murine acute GVHD severity by human gingival tissue-derived mesenchymal stem cells via the CD39 pathways. Cell Death & Disease. 10: 13. PMID 30622237 DOI: 10.1038/S41419-018-1273-7 |
0.462 |
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| 2019 |
Watkins B, Suessmuth Y, Betz K, Yu A, Bratrude B, Qayed M, Pellegrini K, Bosinger S, Langston A, Horan JT, Blazar BR, Kean L. Transcriptomic Analysis of CD4+ T Cell Dysfunction during Gvhd: Evidence for Profound Reprograming of T Cell Signaling during Acute Gvhd That Is Controlled during CD28:CD80/86 Costimulation Blockade with Abatacept Blood. 134: 596-596. DOI: 10.1182/Blood-2019-131955 |
0.457 |
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| 2019 |
Khuat LT, Le CT, Pai C, Shields-Cutler R, Holtan S, Rashidi A, Parker S, Knights D, Luna JI, Dunai C, Wang Z, Sturgill IR, Stoffel K, Merleev AA, Maverakis E, ... ... Blazar BR, et al. Obesity-Induced Microbiome Alterations Result in Severe Gastrointestinal Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation Blood. 134: 1922-1922. DOI: 10.1182/Blood-2019-127743 |
0.395 |
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| 2019 |
Davis Z, Felices M, Lenvik TR, Badal S, Hinderlie P, Blazar BR, Vallera DA, Miller JS. PD-1 Is Expressed at Low Levels on All Peripheral Blood Natural Killer Cells but Is a Significant Suppressor of NK Function Against PD-1 Ligand Expressing Tumor Targets Blood. 134: 621-621. DOI: 10.1182/Blood-2019-127261 |
0.34 |
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| 2019 |
Bruce DW, Kolupaev O, Bommiasamy H, Stefanski H, Blazar BR, Coghill JM, Serody JS. Third Party Type 2 Innate Lymphoid Cells Treat and Prevent GI Tract Acute GvHD Blood. 134: 3205-3205. DOI: 10.1182/Blood-2019-126848 |
0.53 |
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| 2019 |
Miller JS, Bjordahl R, Gaidarova S, Mahmood S, Rogers P, Moyar G, Blazar BR, Kaufman DS, Valamehr B, Cichocki F. iPSC-Derived NK Cells Synergize with T Cells and Anti-PD-1 Antibody to Mediate Durable Anti-Tumor Responses In Vivo Blood. 134: 1933-1933. DOI: 10.1182/Blood-2019-124961 |
0.478 |
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| 2019 |
Cichocki F, Woan K, Wu C, Blazar BR, Bjordahl R, Valamehr B, Miller JS. NK Cells Lacking CD38 Are Resistant to Oxidative Stress-Induced Death Blood. 134: 3215-3215. DOI: 10.1182/Blood-2019-124490 |
0.443 |
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| 2019 |
Shrestha B, Walton K, Reff J, Sagatys EM, Tu N, Boucher JC, Ghafoor T, Pidala J, Blazar BR, Anasetti C, Betts BC, Davila ML. Human CD83 Targeted Chimeric Antigen Receptor T Cell for the Prevention of Graft Versus Host Disease and Treatment of Myeloid Leukemia Blood. 134: 196-196. DOI: 10.1182/Blood-2019-124031 |
0.509 |
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| 2019 |
Brandstadter JD, Perkey E, Gaudette BT, Carrington L, Gomez-Atria D, Blazar BR, Ludewig B, Tikhonova A, Aifantis I, Allman D, Maillard I. Dll1 and Dll4 Notch Ligands Prime T Cell Alloimmunity and Are Expressed in Non-Overlapping Populations of Fibroblastic Stromal Cells in Spleen and Lymph Nodes at the Onset of Gvhd Blood. 134: 588-588. DOI: 10.1182/Blood-2019-123533 |
0.494 |
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| 2019 |
Okoev G, Weisdorf DJ, Wagner JE, Blazar BR, MacMillan ML, DeFor TE, Lazaryan A, El Jurdi NH, Holtan S, Brunstein CG, Betts BC, Takahashi T, Bachanova V, Warlick ED, Rashidi A, et al. Outcomes of Chronic Graft-Versus-Host Disease (cGVHD) Following Matched Sibling Donor (MSD) Versus Umbilical Cord Blood Transplant (UCBT) Blood. 134: 2009-2009. DOI: 10.1182/Blood-2019-123421 |
0.341 |
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| 2019 |
Stefanski H, Brunstein CG, McKenna DH, Sumstad D, Miller JS, Blazar BR, DeFor TE, Boitano AE, Cooke MP, Raffel GD, Davis JC, Wagner JE. Mgta-456, an Aryl Hydrocarbon Receptor (AHR) Antagonist Based Expansion of CD34+ Hematopoietic Stem Cells (HSC), Permits Selection of Better HLA Matched Cord Blood Units (CBUs) and Promotes Faster Neutrophil Recovery and Uniform Engraftment with Potentially Less Acute Graft-Vs-Host Disease (GVHD) Blood. 134: 804-804. DOI: 10.1182/Blood-2019-122329 |
0.432 |
|
| 2019 |
Rosato PC, Wijeyesinghe S, Stolley JM, Nelson C, Davis RL, Manlove LS, Pennell CA, Blazar BR, Chen CC, Geller MA, Vezys V, Masopust D. Abstract B182: Repurposing antiviral T-cells to fight tumors Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B182 |
0.403 |
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| 2019 |
Truscott J, Guan X, Liu W, Li Y, Beyatli S, Metwali A, Urban JF, Elliott DE, Blazar BR, Ince MN. Su1897 – Intestinal Immune Conditioning with Helminths Employ Host T Helper 2 (TH2) Pathway to Induce Mixed Chimerism and Regulate Colitis Associated with Graft-Versus-Host Disease Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)38534-8 |
0.398 |
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| 2019 |
Guan X, Metwali A, Truscott J, Li Y, Weinstock JV, Urban JF, Blazar BR, Elliott DE, Ince MN. Su1889 – T Helper 2 (TH2)-Mediated Regulation of Antigen-Specific and Granulomatous Th1 Response Requires TGFβ Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)38526-9 |
0.358 |
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| 2019 |
Blazar BR. Immune Regulatory Cell Biology and Clinical Applications to Prevent or Treat Acute Graft-Versus-Host Disease Engineering. 5: 98-105. DOI: 10.1016/J.Eng.2018.11.016 |
0.528 |
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| 2019 |
Bader CS, Barreras H, Lightbourn CO, Copsel SN, Wolf D, Meng J, Ahn J, Komanduri KV, Blazar BR, Jin L, Barber GN, Roy S, Levy RB. The Innate Immune Sensor Sting Promotes Donor CD8+ T Cell Activation and Recipient APC Death Early after Preclinical Allogeneic Hematopoietic Stem Cell Transplantation Blood. 134: 3202-3202. DOI: 10.1016/J.Bbmt.2019.12.099 |
0.581 |
|
| 2019 |
Holtan SG, Shabaneh A, Rashidi A, Betts BC, MacMillan ML, Ustun C, Amin K, Vaughn B, Howard J, Khoruts A, Knights D, Arora M, Defor TE, Johnson D, Panoskaltsis-Mortari A, ... Blazar BR, et al. RNA Sequencing of Intestinal Biopsies Expands the T Cell-Centric Paradigm of Steroid-Refractory Acute Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 25. DOI: 10.1016/J.Bbmt.2018.12.673 |
0.473 |
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| 2019 |
Watkins BK, Qayed M, Bratrude B, Betz K, Sinclair S, Suessmuth Y, Rhodes J, Yu A, Cribbin K, Dean C, Narayan A, Hunt D, Schwartz N, Hebert K, Pasquini MC, ... ... Blazar BR, et al. T Cell Costimulation Blockade with CTLA4-Ig (Abatacept) for Acute Gvhd Prevention in HLA Matched and Mismatched Unrelated Donor Transplantation: Results of the First Phase 2 Trial Biology of Blood and Marrow Transplantation. 25. DOI: 10.1016/J.Bbmt.2018.12.129 |
0.301 |
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| 2019 |
Jagasia M, Salhotra A, Bachier CR, Essell JH, Weisdorf DJ, Lazaryan A, Zoghi B, Green LS, Schueller O, Zanin-Zhorov A, Weiss JM, Eiznhamer DA, Aggarwal SK, Blazar BR, Lee SJ. KD025-208: A Phase 2a Study of KD025 for Patients with Chronic Graft Versus Host Disease (cGVHD) - Pharmacodynamics (PD) and Updated Results Biology of Blood and Marrow Transplantation. 25: S28-S29. DOI: 10.1016/J.Bbmt.2018.12.100 |
0.372 |
|
| 2019 |
Whangbo J, Kim HT, Stewart J, Leonard L, Poryanda S, Silverstein S, Kim S, Reynolds C, Fields M, Verrill K, Lee M, Margossian S, Duncan C, Lehmann LE, Nikiforow S, ... ... Blazar BR, et al. Individual Patient Dose-Escalated Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease in Children and Adults: Safety, Efficacy and Immune Correlates Biology of Blood and Marrow Transplantation. 25: S16-S17. DOI: 10.1016/J.Bbmt.2018.12.084 |
0.36 |
|
| 2018 |
Betts BC, Locke FL, Sagatys EM, Pidala J, Walton K, Menges M, Reff J, Saha A, Djeu JY, Kiluk JV, Lee MC, Kim J, Kang CW, Tang CA, Frieling J, ... ... Blazar BR, et al. Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity. Frontiers in Immunology. 9: 2887. PMID 30574153 DOI: 10.3389/Fimmu.2018.02887 |
0.555 |
|
| 2018 |
Verghese DA, Chun N, Paz K, Fribourg M, Woodruff TM, Flynn R, Hu Y, Xiong H, Zhang W, Yi Z, Du J, Blazar BR, Heeger PS. C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans. Jci Insight. 3. PMID 30568034 DOI: 10.1172/Jci.Insight.124646 |
0.797 |
|
| 2018 |
Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, Sartoris S, Solito S, Mandruzzato S, Vascotto F, Hippen KL, Mondanelli G, Grohmann U, Piro G, Carbone C, ... ... Blazar BR, et al. Induction of immunosuppressive functions and NF-κB by FLIP in monocytes. Nature Communications. 9: 5193. PMID 30518925 DOI: 10.1038/S41467-018-07654-4 |
0.415 |
|
| 2018 |
Rashidi A, Shanley R, Holtan SG, MacMillan ML, Blazar BR, Khoruts A, Weisdorf DJ. Pretransplant Serum Citrulline Predicts Acute Graft-versus-Host Disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 24: 2190-2196. PMID 30454871 DOI: 10.1016/J.Bbmt.2018.06.036 |
0.378 |
|
| 2018 |
Amin K, Yaqoob U, Schultz B, Vaughn BP, Khoruts A, Howard JR, DeFor TE, Forster C, Meyer C, Gandhi I, Weisdorf DJ, Rashidi A, MacMillan ML, Blazar BR, Panoskaltsis-Mortari A, et al. Amphiregulin in intestinal acute graft-versus-host disease: a possible diagnostic and prognostic aid. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 30425334 DOI: 10.1038/S41379-018-0170-Z |
0.359 |
|
| 2018 |
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, ... ... Blazar BR, et al. Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism. Cell. PMID 30392958 DOI: 10.1016/J.Cell.2018.10.001 |
0.492 |
|
| 2018 |
Knaus HA, Berglund S, Hackl H, Blackford AL, Zeidner JF, Montiel-Esparza R, Mukhopadhyay R, Vanura K, Blazar BR, Karp JE, Luznik L, Gojo I. Signatures of CD8+ T cell dysfunction in AML patients and their reversibility with response to chemotherapy. Jci Insight. 3. PMID 30385732 DOI: 10.1172/Jci.Insight.120974 |
0.483 |
|
| 2018 |
Xing Y, Smith MJ, Goetz CA, McElmurry RT, Parker SL, Min D, Hollander GA, Weinberg KI, Tolar J, Stefanski HE, Blazar BR. Thymic Epithelial Cell Support of Thymopoiesis Does Not Require . Journal of Immunology (Baltimore, Md. : 1950). PMID 30373854 DOI: 10.4049/Jimmunol.1800670 |
0.465 |
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| 2018 |
Li Y, Guan X, Liu W, Chen HL, Truscott J, Beyatli S, Metwali A, Weiner GJ, Zavazava N, Blumberg RS, Urban JF, Blazar BR, Elliott DE, Ince MN. Helminth-Induced Production of TGF-β and Suppression of Graft-versus-Host Disease Is Dependent on IL-4 Production by Host Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 30291167 DOI: 10.4049/Jimmunol.1700638 |
0.429 |
|
| 2018 |
Paz K, Flynn R, Du J, Qi J, Luznik L, Maillard I, MacDonald KP, Hill GR, Serody JS, Murphy WJ, Sage PT, Sharpe AH, Miklos D, Culter CS, Koreth J, ... ... Blazar B, et al. Small-molecule BCL6 inhibitor effectively treats mice with non-sclerodermatous chronic graft-versus-host disease. Blood. PMID 30279226 DOI: 10.1182/Blood-2018-03-839993 |
0.741 |
|
| 2018 |
Li Y, Liu W, Guan X, Truscott J, Creemers JW, Chen HL, Pesu M, El Abiad RG, Karacay B, Urban JF, Elliott DE, Kaplan MH, Blazar BR, Ince MN. STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 30266770 DOI: 10.4049/Jimmunol.1700808 |
0.394 |
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| 2018 |
Kolupaev OV, Dant TA, Bommiasamy H, Bruce DW, Fowler KA, Tilley SL, McKinnon KP, Sarantopoulos S, Blazar BR, Coghill JM, Serody JS. Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD. Blood Advances. 2: 2307-2319. PMID 30228128 DOI: 10.1182/Bloodadvances.2017014977 |
0.549 |
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| 2018 |
Priyadharshini B, Loschi M, Newton RH, Zhang JW, Finn KK, Gerriets VA, Huynh A, Rathmell JC, Blazar BR, Turka LA. Cutting Edge: TGF-β and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets. Journal of Immunology (Baltimore, Md. : 1950). PMID 30209190 DOI: 10.4049/Jimmunol.1800311 |
0.365 |
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| 2018 |
Radojcic V, Paz K, Chung J, Du J, Perkey ET, Flynn R, Ivcevic S, Zaiken M, Friedman A, Yan M, Pletneva MA, Sarantopoulos S, Siebel CW, Blazar BR, Maillard I. Notch signaling mediated by Delta-like1/4 ligands controls the pathogenesis of chronic graft-versus-host disease in mice. Blood. PMID 30181175 DOI: 10.1182/Blood-2018-03-841155 |
0.75 |
|
| 2018 |
Jaglowski SM, Blazar BR. How ibrutinib, a B-cell malignancy drug, became an FDA-approved second-line therapy for steroid-resistant chronic GVHD. Blood Advances. 2: 2012-2019. PMID 30108109 DOI: 10.1182/Bloodadvances.2018013060 |
0.38 |
|
| 2018 |
McDonald-Hyman C, Muller JT, Loschi M, Thangavelu G, Saha A, Kumari S, Reichenbach DK, Smith MJ, Zhang G, Koehn BH, Lin J, Mitchell JS, Fife BT, Panoskaltsis-Mortari A, Feser CJ, ... ... Blazar BR, et al. The vimentin intermediate filament network restrains regulatory T-cell suppression of graft-versus-host disease. The Journal of Clinical Investigation. PMID 30106752 DOI: 10.1172/Jci95713 |
0.756 |
|
| 2018 |
Watkins BK, Tkachev V, Furlan SN, Hunt DJ, Betz K, Yu A, Brown M, Poirier N, Zheng HB, Taraseviciute A, Colonna L, Mary C, Blancho G, Soulillou JP, Panoskaltsis-Mortari A, ... ... Blazar BR, et al. CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates. The Journal of Clinical Investigation. PMID 30102255 DOI: 10.1172/Jci98793 |
0.525 |
|
| 2018 |
Holtan SG, DeFor TE, Panoskaltsis-Mortari A, Khera N, Levine JE, Flowers MED, Lee SJ, Inamoto Y, Chen GL, Mayer S, Arora M, Palmer J, Cutler CS, Arai S, Lazaryan A, ... ... Blazar BR, et al. Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802. Blood Advances. 2: 1882-1888. PMID 30087106 DOI: 10.1182/Bloodadvances.2018017343 |
0.317 |
|
| 2018 |
Warlick ED, DeFor TE, Bejanyan N, Holtan S, MacMillan M, Blazar BR, Dusenbery K, Arora M, Bachanova V, Cooley S, Lazaryan A, McGlave P, Miller JS, Rashidi A, Slungaard A, et al. Reduced Intensity Conditioning Followed by Related and Unrelated Allografts for Hematologic Malignancies: Expanded Analysis and Long Term Follow-Up. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 30077015 DOI: 10.1016/J.Bbmt.2018.07.038 |
0.388 |
|
| 2018 |
Cichocki F, Wu CY, Zhang B, Felices M, Tesi B, Tuininga K, Dougherty P, Taras E, Hinderlie P, Blazar BR, Bryceson YT, Miller JS. ARID5B regulates metabolic programming in human adaptive NK cells. The Journal of Experimental Medicine. PMID 30061358 DOI: 10.1084/Jem.20172168 |
0.342 |
|
| 2018 |
Rashidi A, Shanley R, Yohe SL, Thyagarajan B, Curtsinger J, Anasetti C, Waller EK, Scott BL, Blazar BR, Weisdorf DJ. Recipient single nucleotide polymorphisms in Paneth cell antimicrobial peptide genes and acute graft-versus-host disease: analysis of BMT CTN-0201 and -0901 samples. British Journal of Haematology. PMID 30004111 DOI: 10.1111/Bjh.15492 |
0.395 |
|
| 2018 |
Newton RH, Shrestha S, Sullivan JM, Yates KB, Compeer EB, Ron-Harel N, Blazar BR, Bensinger SJ, Haining WN, Dustin ML, Campbell DJ, Chi H, Turka LA. Maintenance of CD4 T cell fitness through regulation of Foxo1. Nature Immunology. PMID 29988091 DOI: 10.1038/S41590-018-0157-4 |
0.476 |
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| 2018 |
Borges da Silva H, Beura LK, Wang H, Hanse EA, Gore R, Scott MC, Walsh DA, Block KE, Fonseca R, Yan Y, Hippen KL, Blazar BR, Masopust D, Kelekar A, Vulchanova L, et al. The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8 T cells. Nature. PMID 29973721 DOI: 10.1038/S41586-018-0282-0 |
0.438 |
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| 2018 |
Sarhan D, Brandt L, Felices M, Guldevall K, Lenvik T, Hinderlie P, Curtsinger J, Warlick E, Spellman SR, Blazar BR, Weisdorf DJ, Cooley S, Vallera DA, Önfelt B, Miller JS. 161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS. Blood Advances. 2: 1459-1469. PMID 29941459 DOI: 10.1182/Bloodadvances.2017012369 |
0.483 |
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| 2018 |
Habtetsion T, Ding ZC, Pi W, Li T, Lu C, Chen T, Xi C, Spartz H, Liu K, Hao Z, Mivechi N, Huo Y, Blazar BR, Munn DH, Zhou G. Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death. Cell Metabolism. PMID 29887396 DOI: 10.1016/J.Cmet.2018.05.012 |
0.372 |
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| 2018 |
Sarhan D, Hippen KL, Lemire A, Hying S, Luo X, Lenvik T, Curtsinger J, Davis Z, Zhang B, Cooley S, Cichocki F, Blazar BR, Miller JS. Adaptive NK cells resist regulatory T cell suppression driven by IL-37. Cancer Immunology Research. PMID 29784636 DOI: 10.1158/2326-6066.Cir-17-0498 |
0.459 |
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| 2018 |
Pennell CA, Barnum JL, McDonald-Hyman CS, Panoskaltsis-Mortari A, Riddle MJ, Xiong Z, Loschi M, Thangavelu G, Campbell HM, Storlie MD, Refaeli Y, Furlan SN, Jensen MC, Kean LS, Miller JS, ... ... Blazar BR, et al. Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29735365 DOI: 10.1016/J.Ymthe.2018.04.006 |
0.771 |
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| 2018 |
Owen DL, Mahmud SA, Vang KB, Kelly RM, Blazar BR, Smith KA, Farrar MA. Identification of Cellular Sources of IL-2 Needed for Regulatory T Cell Development and Homeostasis. Journal of Immunology (Baltimore, Md. : 1950). PMID 29728511 DOI: 10.4049/Jimmunol.1800097 |
0.495 |
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| 2018 |
Blazar BR, MacDonald KPA, Hill GR. Immune regulatory cell infusion for graft-versus-host disease prevention and therapy. Blood. PMID 29728401 DOI: 10.1182/Blood-2017-11-785865 |
0.518 |
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| 2018 |
Zitzer NC, Snyder K, Meng X, Taylor PA, Efebera YA, Devine SM, Blazar BR, Garzon R, Ranganathan P. MicroRNA-155 Modulates Acute Graft-versus-Host Disease by Impacting T Cell Expansion, Migration, and Effector Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 29720426 DOI: 10.4049/Jimmunol.1701465 |
0.434 |
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| 2018 |
Bejanyan N, Brunstein CG, Cao Q, Lazaryan A, Luo X, Curtsinger J, Mehta RS, Warlick E, Cooley SA, Blazar BR, Miller JS, Weisdorf D, Wagner JE, Verneris MR. Delayed immune reconstitution after allogeneic transplantation increases the risks of mortality and chronic GVHD. Blood Advances. 2: 909-922. PMID 29678809 DOI: 10.1182/Bloodadvances.2017014464 |
0.531 |
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| 2018 |
Stefanski HE, Jonart L, Goren E, Mulé JJ, Blazar BR. A novel approach to improve immune effector responses post transplant by restoration of CCL21 expression. Plos One. 13: e0193461. PMID 29617362 DOI: 10.1371/Journal.Pone.0193461 |
0.495 |
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| 2018 |
Osborn MJ, Lees CJ, McElroy AN, Merkel SC, Eide CR, Mathews W, Feser CJ, Tschann M, McElmury RT, Webber BR, Kim CJ, Blazar BR, Tolar J. CRISPR/Cas9-Based Cellular Engineering for Targeted Gene Overexpression. International Journal of Molecular Sciences. 19. PMID 29565806 DOI: 10.3390/Ijms19040946 |
0.793 |
|
| 2018 |
Taraseviciute A, Tkachev V, Ponce R, Turtle CJ, Snyder JM, Liggitt HD, Myerson D, Gonzalez-Cuyar L, Baldessari A, English C, Yu A, Zheng H, Furlan SN, Hunt DJ, Hoglund V, ... ... Blazar BR, et al. Chimeric Antigen Receptor T Cell-Mediated Neurotoxicity in Non-Human Primates. Cancer Discovery. PMID 29563103 DOI: 10.1158/2159-8290.Cd-17-1368 |
0.497 |
|
| 2018 |
Wu Y, Schutt S, Paz K, Zhang M, Flynn RP, Bastian D, Sofi MH, Nguyen H, Dai M, Liu C, Chang YJ, Blazar BR, Yu XZ. MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice. Blood. PMID 29530952 DOI: 10.1182/Blood-2017-06-789321 |
0.701 |
|
| 2018 |
Zhang R, Sage PT, Finn K, Huynh A, Blazar BR, Marangoni F, Mempel TR, Sharpe AH, Turka LA. Correction: B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 29475985 DOI: 10.4049/Jimmunol.1800150 |
0.433 |
|
| 2018 |
Prestipino A, Emhardt AJ, Aumann K, O'Sullivan D, Gorantla SP, Duquesne S, Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, ... ... Blazar BR, et al. Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Science Translational Medicine. 10. PMID 29467301 DOI: 10.1126/Scitranslmed.Aam7729 |
0.332 |
|
| 2018 |
Romee R, Cooley S, Berrien-Elliott MM, Westervelt P, Verneris MR, Wagner JE, Weisdorf DJ, Blazar BR, Ustun C, DeFor TE, Vivek S, Peck L, DiPersio JF, Cashen AF, Kyllo R, et al. First-in-human Phase 1 Clinical Study of the IL-15 Superagonist Complex ALT-803 to Treat Relapse after Transplantation. Blood. PMID 29463563 DOI: 10.1182/Blood-2017-12-823757 |
0.476 |
|
| 2018 |
Hülsdünker J, Ottmüller KJ, Neeff HP, Koyama M, Gao Z, Thomas OS, Follo M, Al-Ahmad A, Prinz G, Duquesne S, Dierbach H, Kirschnek S, Lämmermann T, Blaser MJ, Fife BT, ... Blazar BR, et al. Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset. Blood. PMID 29463561 DOI: 10.1182/Blood-2017-10-812891 |
0.496 |
|
| 2018 |
Zhang C, Shen H, Lu Y, Gao J, Zhang S, Gu J, Lu H, Xia Y, Zhu Q, Qian X, Zhang F, Hippen KL, Blazar BR, Lu L, Wang X. miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg). Cell Death & Disease. 9: 290. PMID 29459719 DOI: 10.1038/S41419-018-0298-2 |
0.44 |
|
| 2018 |
Hippen KL, Loschi M, Nicholls J, MacDonald KPA, Blazar BR. Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease. Frontiers in Immunology. 9: 57. PMID 29445371 DOI: 10.3389/Fimmu.2018.00057 |
0.354 |
|
| 2018 |
Zeiser R, Sarantopoulos S, Blazar BR. B-cell targeting in chronic Graft-versus-Host disease. Blood. PMID 29437591 DOI: 10.1182/Blood-2017-11-784017 |
0.409 |
|
| 2018 |
Mathew NR, Baumgartner F, Braun L, O'Sullivan D, Thomas S, Waterhouse M, Müller TA, Hanke K, Taromi S, Apostolova P, Illert AL, Melchinger W, Duquesne S, Schmitt-Graeff A, Osswald L, ... ... Blazar BR, et al. Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nature Medicine. PMID 29431743 DOI: 10.1038/Nm.4484 |
0.526 |
|
| 2018 |
Felices M, Lenvik AJ, McElmurry R, Chu S, Hinderlie P, Bendzick L, Geller MA, Tolar J, Blazar BR, Miller JS. Continuous treatment with IL-15 exhausts human NK cells via a metabolic defect. Jci Insight. 3. PMID 29415897 DOI: 10.1172/Jci.Insight.96219 |
0.398 |
|
| 2018 |
Du J, Flynn R, Paz K, Ren HG, Ogata Y, Zhang Q, Gafken PR, Storer BE, Roy NH, Burkhardt JK, Mathews W, Tolar J, Lee SJ, Blazar BR, Paczesny S. Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients. Blood. PMID 29348127 DOI: 10.1182/Blood-2017-08-800623 |
0.735 |
|
| 2018 |
Sharma MD, Rodriguez PC, Koehn BH, Baban B, Cui Y, Guo G, Shimoda M, Pacholczyk R, Shi H, Lee EJ, Xu H, Johnson TS, He Y, Mergoub T, Venable C, ... ... Blazar BR, et al. Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors. Immunity. 48: 91-106.e6. PMID 29343444 DOI: 10.1016/J.Immuni.2017.12.014 |
0.43 |
|
| 2018 |
Koreth J, Kim HT, Lange PB, Poryanda SJ, Reynolds CG, Chamling Rai S, Armand P, Cutler CS, Ho VT, Glotzbecker B, Yusuf R, Nikiforow S, Chen YB, Dey B, McMasters M, ... ... Blazar BR, et al. Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: randomized phase II results. Haematologica. PMID 29326124 DOI: 10.3324/Haematol.2017.176859 |
0.388 |
|
| 2018 |
Canter RJ, Aguilar E, Wang Z, Le C, Khuat L, Dunai C, Rebhun R, Tarantal A, Blazar BR, Monjazeb A, Murphy WJ. Obesity results in higher PD-1-mediated T-cell suppression but greater T-cell effector functions following blockade. Journal of Clinical Oncology. 36: 65-65. DOI: 10.1200/Jco.2018.36.5_Suppl.65 |
0.4 |
|
| 2018 |
Furlan SN, Lopez C, Tkachev V, Betz K, Hunt DJ, Hibbard J, Blazar BR, Trapnell C, Kean L. IL2 and Rapamycin Enhance Persistence of Adoptively-Transferred Ex-Vivo Expanded T Regulatory Cells Blood. 132: 2049-2049. DOI: 10.1182/Blood-2018-99-120254 |
0.413 |
|
| 2018 |
Truscott J, Guan X, Liu W, Beyatli S, Metwali A, Elliot DE, Blazar BR, Ince MN. Intestinal Immune Conditioning with Helminths Employs Host T Helper 2 (Th2) Pathway to Induce Mixed Chimerism and Regulate Graft-Versus-Host Disease Blood. 132: 2036-2036. DOI: 10.1182/Blood-2018-99-119377 |
0.539 |
|
| 2018 |
Tkachev V, Furlan SN, Potter EL, Zheng H, Hunt DJ, Colonna L, Taraseviciute A, Carlson JM, Betz K, Yu A, Hoffman M, Baldessari A, Herrin S, Olvera J, Littlewood C, ... ... Blazar BR, et al. Uncovering the Molecular Signature of Pathogenic Tissue-Infiltrating T Cells during Acute Graft-Versus-Host Disease Blood. 132: 805-805. DOI: 10.1182/Blood-2018-99-113652 |
0.533 |
|
| 2018 |
MacMillan ML, Hippen KL, McKenna DH, DeFor TE, Warlick ED, Brunstein CG, Miller JS, Weisdorf DJ, Blazar BR, Wagner JE. First-in-Human Clinical Trial to Determine the Safety and Potency of Inducible T Regulatory Cells after Allogeneic Hematopoietic Cell Transplantation Blood. 132: 2112-2112. DOI: 10.1182/Blood-2018-99-113100 |
0.464 |
|
| 2018 |
MacMillan ML, Holtan SG, Rashidi A, DeFor TE, Brunstein CG, Wagner JE, Blazar BR, Weisdorf DJ. Validation of Minnesota Acute GVHD Risk Score and Identification of New Factors Associated with Initial Response to Steroids: Not All GVHD Is Created Equal Blood. 132: 67-67. DOI: 10.1182/Blood-2018-99-113085 |
0.321 |
|
| 2018 |
Yang J, Ramadan A, Reichenbach D, Loschi M, Zhang J, Griesenauer B, Liu H, Hippen KL, Blazar BR, Paczesny S. ST2 and ROR-γ-t Roles in Intestinal Regulatory T Cells Blood. 132: 66-66. DOI: 10.1182/Blood-2018-99-113003 |
0.51 |
|
| 2018 |
Jagasia M, Salhotra A, Bachier CR, Essell J, Weisdorf DJ, Zoghi B, Green LS, Schueller O, Zanin-Zhorov A, Weiss JM, Eiznhamer D, Aggarwal SK, Blazar BR, Lee SJ. KD025-208: A Phase 2a Study of KD025 for Patients with Chronic Graft Versus Host Disease (cGVHD) — Pharmacodynamics and Updated Results Blood. 132: 602-602. DOI: 10.1182/Blood-2018-99-111896 |
0.41 |
|
| 2018 |
Perkey E, Carrington L, Chung J, Granadier D, Dils A, Friedman A, Tikhonova A, Blazar BR, Koch U, Labrecque N, Radtke F, Siebel C, Aifantis I, Maillard I. Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease Blood. 132: 810-810. DOI: 10.1182/Blood-2018-99-110258 |
0.537 |
|
| 2018 |
Tkachev V, Kuhnert F, Furlan SN, Zheng H, Hunt DJ, Colonna L, Carlson JM, Taraseviciute A, Panoskaltsis-Mortari A, Hoglund V, Betz K, Yu A, Blazar BR, Carpenter S, Harari O, et al. Pharmacologic Blockade of Notch/Delta-like Ligand 4 Signaling Protects from Gastrointestinal Acute Graft-Versus-Host Disease in Non-Human Primates Blood. 132: 2027-2027. DOI: 10.1182/Blood-2018-99-110030 |
0.532 |
|
| 2018 |
Lineburg KE, Texier LL, Melino M, Wang R, Clouston A, Blazar BR, McGuckin MA, Villadangos JA, Mintern JD, MacDonald KPA. Ubiquitin LigaseMARCH8 attenuates Graft versus Host Disease via Regulation of Gut Epithelial Cell Surface MHC II Expression Transplantation. 102. DOI: 10.1097/01.Tp.0000543013.84163.3A |
0.38 |
|
| 2018 |
Kamihara Y, Forcade E, Koreth J, Kim HT, Liu H, Douchet I, Kubo T, Whangbo J, Hirakawa M, Nikiforow S, Ho VT, Armand P, Cutler C, Alyea EP, Blanco P, ... Blazar BR, et al. Low-Dose Interleukin-2 Therapy Activates Circulating T Follicular Regulatory Cells (cTFR) and Suppresses Circulating T Follicular Helper Cells (cTFH) in Patients with Chronic Gvhd Biology of Blood and Marrow Transplantation. 24. DOI: 10.1016/J.Bbmt.2017.12.617 |
0.472 |
|
| 2018 |
Stefanski H, Singh J, Norris B, Schumacher R, Wagner JE, Blazar BR, Zuniga-Pflucker JC. Robust Progenitor T-Cell Production From Human Hematopoietic Progenitor Cell Expanded with Stemregenin-1 Biology of Blood and Marrow Transplantation. 24. DOI: 10.1016/J.Bbmt.2017.12.434 |
0.471 |
|
| 2018 |
Amin K, Usman Y, Schultz B, Vaughn B, Howard J, Khoruts A, Defor TE, Forster C, Rashidi A, Weisdorf DJ, MacMillan ML, Blazar BR, Mortari A, Holtan SG. Low Amphiregulin Expression in Intestinal Biopsies of Patients with Acute Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 24: S188. DOI: 10.1016/J.Bbmt.2017.12.142 |
0.339 |
|
| 2018 |
Holtan SG, Defor TE, Howard A, Pidala JA, Levine JE, Wu JM, Khera N, Lee SJ, Bolaños-Meade J, Ho VT, Alousi AM, Inamoto Y, Chen GL, Arora M, Palmer J, ... ... Blazar BR, et al. Amphiregulin Modifies the Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN Acute Gvhd Therapy Trials Biology of Blood and Marrow Transplantation. 24. DOI: 10.1016/J.Bbmt.2017.12.128 |
0.32 |
|
| 2018 |
Rashidi A, Shanley R, Holtan SG, MacMillan ML, Yohe S, Thyagarajan B, Curtsinger J, Anasetti C, Waller EK, Miller JS, Blazar BR, Weisdorf DJ. Single Nucleotide Polymorphisms of Paneth Cell Antimicrobial Alpha Defensin-5 (DEFA5) are Associated with Acute Graft-Versus-Host Disease: Results From Analysis of BMT-CTN0201 Samples Biology of Blood and Marrow Transplantation. 24: S174-S175. DOI: 10.1016/J.Bbmt.2017.12.124 |
0.336 |
|
| 2017 |
Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, et al. Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Frontiers in Immunology. 8: 1844. PMID 29379498 DOI: 10.3389/Fimmu.2017.01844 |
0.432 |
|
| 2017 |
Smith AR, Rota IA, Maio S, Massaad MJ, Lund TC, Notarangelo LD, Holländer GA, Blazar BR. Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT. Blood Advances. 1: 2083-2087. PMID 29296855 DOI: 10.1182/Bloodadvances.2017010926 |
0.311 |
|
| 2017 |
Zeiser R, Blazar BR. Pathophysiology of Chronic Graft-versus-Host Disease and Therapeutic Targets. The New England Journal of Medicine. 377: 2565-2579. PMID 29281578 DOI: 10.1056/Nejmra1703472 |
0.384 |
|
| 2017 |
Bachanova V, Sarhan D, DeFor TE, Cooley S, Panoskaltsis-Mortari A, Blazar BR, Curtsinger JM, Burns L, Weisdorf DJ, Miller JS. Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cells. Cancer Immunology, Immunotherapy : Cii. PMID 29218366 DOI: 10.1007/S00262-017-2100-1 |
0.434 |
|
| 2017 |
Williams RL, Cooley S, Bachanova V, Blazar BR, Weisdorf DJ, Miller JS, Verneris MR. Recipient T Cell Exhaustion and Successful Adoptive Transfer of Haploidentical Natural Killer Cells. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 29197679 DOI: 10.1016/J.Bbmt.2017.11.022 |
0.518 |
|
| 2017 |
Zeiser R, Blazar BR. Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy. The New England Journal of Medicine. 377: 2167-2179. PMID 29171820 DOI: 10.1056/Nejmra1609337 |
0.454 |
|
| 2017 |
Wang KS, Kim HT, Nikiforow S, Heubeck AT, Ho VT, Koreth J, Alyea EP, Armand P, Blazar BR, Soiffer RJ, Antin JH, Cutler CS, Ritz J. Antibodies Targeting Surface Membrane Antigens in Patients with Chronic Graft-Versus-Host Disease. Blood. PMID 29138220 DOI: 10.1182/Blood-2017-08-801001 |
0.39 |
|
| 2017 |
Zhang R, Sage PT, Finn K, Huynh A, Blazar BR, Marangoni F, Mempel TR, Sharpe AH, Turka LA. B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 29093061 DOI: 10.4049/Jimmunol.1700409 |
0.502 |
|
| 2017 |
Turcotte LM, DeFor TE, Newell LF, Cutler CS, Verneris MR, Wu J, Howard A, MacMillan ML, Antin JH, Vercellotti GM, Slungaard A, Blazar BR, Weisdorf DJ, Panoskaltsis-Mortari A, Holtan SG. Donor and recipient plasma follistatin levels are associated with acute GvHD in Blood and Marrow Transplant Clinical Trials Network 0402. Bone Marrow Transplantation. PMID 29058696 DOI: 10.1038/Bmt.2017.236 |
0.374 |
|
| 2017 |
Gartlan KH, Bommiasamy H, Paz K, Wilkinson AN, Owen M, Reichenbach DK, Banovic T, Wehner K, Buchanan F, Varelias A, Kuns RD, Chang K, Fedoriw Y, Shea T, Coghill J, ... ... Blazar BR, et al. A Critical Role for Donor-Derived IL-22 in Cutaneous Chronic GVHD. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28941323 DOI: 10.1111/ajt.14513 |
0.39 |
|
| 2017 |
Tkachev V, Furlan SN, Watkins B, Hunt DJ, Zheng HB, Panoskaltsis-Mortari A, Betz K, Brown M, Schell JB, Zeleski K, Yu A, Kirby I, Cooley S, Miller JS, Blazar BR, et al. Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant. Science Translational Medicine. 9. PMID 28931653 DOI: 10.1126/Scitranslmed.Aan3085 |
0.517 |
|
| 2017 |
Miklos D, Cutler CS, Arora M, Waller EK, Jagasia M, Pusic I, Flowers ME, Logan AC, Nakamura R, Blazar BR, Li Y, Chang S, Lal I, Dubovsky J, James DF, et al. Ibrutinib for chronic graft-versus-host disease after failure of prior therapy. Blood. PMID 28924018 DOI: 10.1182/Blood-2017-07-793786 |
0.437 |
|
| 2017 |
Poe JC, Jia W, Su H, Anand S, Rose JJ, Tata PV, Suthers AN, Jones CD, Kuan PF, Vincent BG, Serody JS, Horwitz ME, Ho VT, Pavletic SZ, Hakim FT, ... ... Blazar BR, et al. An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD. Blood. PMID 28851699 DOI: 10.1182/Blood-2017-05-782466 |
0.418 |
|
| 2017 |
Spanier JA, Sahli NL, Wilson JC, Martinov T, Dileepan T, Burrack AL, Finger EB, Blazar BR, Michels AW, Moran A, Jenkins MK, Fife BT. Increased Effector Memory Insulin-Specific CD4(+)T-cells Correlate with Insulin Autoantibodies in Recent-Onset Type 1 Diabetic Patients. Diabetes. PMID 28842400 DOI: 10.2337/Db17-0666 |
0.427 |
|
| 2017 |
Cichocki F, Valamehr B, Bjordahl R, Zhang B, Rezner B, Rogers P, Gaidarova S, Moreno SK, Tuininga K, Dougherty P, McCullar V, Howard P, Sarhan D, Taras E, Schlums H, ... ... Blazar BR, et al. GSK 3 inhibition drives maturation of NK cells and enhances their antitumor activity. Cancer Research. PMID 28790065 DOI: 10.1158/0008-5472.Can-17-0799 |
0.453 |
|
| 2017 |
Zhang P, Lee JS, Gartlan KH, Schuster IS, Comerford I, Varelias A, Ullah MA, Vuckovic S, Koyama M, Kuns RD, Locke KR, Beckett KJ, Olver SD, Samson LD, Montes de Oca M, ... ... Blazar BR, et al. Eomesodermin promotes the development of type 1 regulatory T (TR1) cells. Science Immunology. 2. PMID 28738016 DOI: 10.1126/Sciimmunol.Aah7152 |
0.556 |
|
| 2017 |
MacDonald KP, Blazar BR, Hill GR. Cytokine mediators of chronic graft-versus-host disease. The Journal of Clinical Investigation. 127: 2452-2463. PMID 28665299 DOI: 10.1172/Jci90593 |
0.468 |
|
| 2017 |
Zanin-Zhorov A, Kumari S, Hippen KL, Merkel SC, MacMillan ML, Blazar BR, Dustin ML. Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity. Scientific Reports. 7: 4258. PMID 28652577 DOI: 10.1038/S41598-017-04053-5 |
0.432 |
|
| 2017 |
Forcade E, Paz K, Flynn R, Griesenauer B, Amet T, Li W, Liu L, Bakoyannis G, Jiang D, Chu HW, Lobera M, Yang J, Wilkes DS, Du J, Gartlan K, ... ... Blazar BR, et al. An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition. Jci Insight. 2. PMID 28614794 DOI: 10.1172/Jci.Insight.92111 |
0.792 |
|
| 2017 |
Holtan SG, Newell LF, Cutler C, Verneris MR, DeFor TE, Wu J, Howard A, MacMillan ML, Antin JH, Blazar BR, Weisdorf DJ, Panoskaltsis-Mortari A. Low EGF in myeloablative allotransplantation: association with severe acute GvHD in BMT CTN 0402. Bone Marrow Transplantation. PMID 28581470 DOI: 10.1038/Bmt.2017.89 |
0.36 |
|
| 2017 |
Dant TA, Lin KL, Bruce DW, Montgomery SA, Kolupaev OV, Bommiasamy H, Bixby LM, Woosley JT, McKinnon KP, Gonzalez FJ, Blazar BR, Vincent BG, Coghill JM, Serody JS. T cell expression of AhR inhibits the maintenance of pTreg cells in the GI tract in acute GvHD. Blood. PMID 28550042 DOI: 10.1182/Blood-2016-08-734244 |
0.593 |
|
| 2017 |
Smith MJ, Reichenbach DK, Parker SL, Riddle MJ, Mitchell J, Osum KC, Mohtashami M, Stefanski HE, Fife BT, Bhandoola A, Hogquist KA, Holländer GA, Zúñiga-Pflücker JC, Tolar J, Blazar BR. T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction. Jci Insight. 2. PMID 28515359 DOI: 10.1172/Jci.Insight.92056 |
0.512 |
|
| 2017 |
Zamora AE, Aguilar EG, Sungur CM, Khuat LT, Dunai C, Lochhead GR, Du J, Pomeroy C, Blazar BR, Longo DL, Venstrom JM, Baumgarth N, Murphy WJ. Licensing delineates helper and effector NK cell subsets during viral infection. Jci Insight. 2. PMID 28515356 DOI: 10.1172/Jci.Insight.87032 |
0.436 |
|
| 2017 |
Xiong Y, Brinkman CC, Famulski KS, Mongodin EF, Lord CJ, Hippen KL, Blazar BR, Bromberg JS. A robust in vitro model for trans-lymphatic endothelial migration. Scientific Reports. 7: 1633. PMID 28487567 DOI: 10.1038/S41598-017-01575-W |
0.42 |
|
| 2017 |
Hippen KL, O'Connor RS, Lemire AM, Saha A, Hanse EA, Tennis NC, Merkel SC, Kelekar A, Riley JL, Levine BL, June CH, Kean LS, MacMillan ML, Miller JS, Wagner JE, ... ... Blazar BR, et al. In vitro induction of human regulatory T-cells (iTregs) using conditions of low tryptophan plus kynurenines. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28470889 DOI: 10.1182/Blood.V128.22.1229.1229 |
0.532 |
|
| 2017 |
Haverkos BM, Abbott D, Hamadani M, Armand P, Flowers ME, Merryman R, Kamdar M, Kanate AS, Saad A, Mehta A, Ganguly S, Fenske TS, Hari P, Lowsky R, Andritsos L, ... ... Blazar BR, et al. PD-1 blockade for relapsed lymphoma post allogeneic hematopoietic cell transplant: high response rate but frequent GVHD. Blood. PMID 28468799 DOI: 10.1182/Blood-2017-01-761346 |
0.309 |
|
| 2017 |
Sckisel GD, Mirsoian A, Minnar CM, Crittenden M, Curti B, Chen JQ, Blazar BR, Borowsky AD, Monjazeb AM, Murphy WJ. Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy. Journal For Immunotherapy of Cancer. 5: 33. PMID 28428882 DOI: 10.1186/S40425-017-0235-4 |
0.458 |
|
| 2017 |
Du J, Paz K, Thangavelu G, Schneidawind D, Baker J, Flynn R, Duramad O, Feser C, Panoskaltsis-Mortari A, Negrin RS, Blazar BR. Invariant natural killer T cells ameliorate murine chronic GVHD by expanding donor regulatory T cells. Blood. PMID 28416503 DOI: 10.1182/Blood-2016-11-752444 |
0.783 |
|
| 2017 |
Bruce DW, Stefanski HE, Vincent BG, Dant TA, Reisdorf S, Bommiasamy H, Serody DA, Wilson JE, McKinnon KP, Shlomchik WD, Armistead PM, Ting JP, Woosley JT, Blazar BR, Zaiss DM, et al. Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease. The Journal of Clinical Investigation. PMID 28375154 DOI: 10.1172/Jci91816 |
0.524 |
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| 2017 |
Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, ... ... Blazar BR, et al. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. The Journal of Clinical Investigation. PMID 28319044 DOI: 10.1172/Jci89535 |
0.547 |
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| 2017 |
Purroy C, Fairchild RL, Tanaka T, Baldwin WM, Manrique J, Madsen JC, Colvin RB, Alessandrini A, Blazar BR, Fribourg M, Donadei C, Maggiore U, Heeger PS, Cravedi P. Erythropoietin Receptor-Mediated Molecular Crosstalk Promotes T Cell Immunoregulation and Transplant Survival. Journal of the American Society of Nephrology : Jasn. PMID 28302753 DOI: 10.1681/Asn.2016101100 |
0.561 |
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| 2017 |
Kamphorst AO, Wieland A, Nasti T, Yang S, Zhang R, Barber DL, Konieczny BT, Daugherty CZ, Koenig L, Yu K, Sica GL, Sharpe AH, Freeman GJ, Blazar BR, Turka LA, et al. Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent. Science (New York, N.Y.). PMID 28280249 DOI: 10.1126/Science.Aaf0683 |
0.418 |
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| 2017 |
Kean LS, Turka LA, Blazar BR. Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy. Immunological Reviews. 276: 192-212. PMID 28258702 DOI: 10.1111/Imr.12523 |
0.489 |
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| 2017 |
Du J, Paz K, Flynn R, Vulic A, Robinson TM, Lineburg KE, Alexander KA, Meng J, Roy S, Panoskaltsis-Mortari A, Loschi M, Hill GR, Serody JS, Maillard I, Miklos D, ... ... Blazar BR, et al. Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production. Blood. PMID 28254742 DOI: 10.1182/Blood-2017-01-758854 |
0.729 |
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| 2017 |
Ranganathan P, Ngankeu A, Zitzer NC, Leoncini P, Yu X, Casadei L, Challagundla K, Reichenbach DK, Garman S, Ruppert AS, Volinia S, Hofstetter J, Efebera YA, Devine SM, Blazar BR, et al. Serum miR-29a Is Upregulated in Acute Graft-versus-Host Disease and Activates Dendritic Cells through TLR Binding. Journal of Immunology (Baltimore, Md. : 1950). PMID 28159900 DOI: 10.4049/Jimmunol.1601778 |
0.308 |
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| 2017 |
Koehn BH, Blazar BR. Role of myeloid-derived suppressor cells in allogeneic hematopoietic cell transplantation. Journal of Leukocyte Biology. PMID 28148718 DOI: 10.1189/Jlb.5Mr1116-464R |
0.515 |
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| 2017 |
Varelias A, Ormerod KL, Bunting MD, Koyama M, Gartlan KH, Kuns RD, Lachner N, Locke KR, Lim CY, Henden AS, Zhang P, Clouston AD, Hasnain SZ, McGuckin MA, Blazar BR, et al. Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome. Blood. PMID 28137828 DOI: 10.1182/Blood-2016-08-732628 |
0.4 |
|
| 2017 |
Jha GG, Gupta S, Tagawa ST, Koopmeiners JS, Vivek S, Dudek AZ, Cooley SA, Blazar BR, Miller JS. A phase II randomized, double-blind study of sipuleucel-T followed by IDO pathway inhibitor, indoximod, or placebo in the treatment of patients with metastatic castration resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 35: 3066-3066. DOI: 10.1200/Jco.2017.35.15_Suppl.3066 |
0.374 |
|
| 2017 |
Holtan SG, DeFor TE, Pidala J, Khera N, Lee SJ, Howard A, Wu J, Bolanos-Meade FJ, Ho VT, Alousi AM, Inamoto Y, Chen G, Arora M, Palmer J, Flowers ME, ... ... Blazar B, et al. Amphiregulin Improves Stratification of the Refined Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN 0302/0802 Blood. 130: 72-72. DOI: 10.1182/Blood.V130.Suppl_1.72.72 |
0.316 |
|
| 2017 |
Cichocki F, Bjordahl R, Gaidarova S, Rogers P, Clarke R, Groff B, Moreno S, Abujarour R, Robinson M, Bonello G, Lee T, Lan W, Rezner B, Abbot S, Sumstad D, ... Blazar B, et al. Clinical Translation of Pluripotent Cell-Derived Off-the-Shelf Natural Killer Cell Cancer Immunotherapy Blood. 130: 656-656. DOI: 10.1182/Blood.V130.Suppl_1.656.656 |
0.477 |
|
| 2017 |
Nikiforow S, Kim HT, Jones KT, Stewart J, Garrity H, Daley H, Richard S, Manduke R, Chammas M, Reynolds C, Burden A, Whangbo J, Blazar B, Armand P, Ho VT, et al. Phase I Trial of Regulatory T-Cell Donor Lymphocyte Infusion Plus Daily Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Versus-Host Disease Blood. 130: 511-511. DOI: 10.1182/Blood.V130.Suppl_1.511.511 |
0.454 |
|
| 2017 |
Forcade E, Kamihara Y, Kim HT, Douchet I, Koreth J, Hirakawa M, Cutler C, Nikiforow S, Ho VT, Armand P, Alyea E, Blanco P, Blazar B, Antin JH, Soiffer RJ, et al. T Follicular Regulatory (TFR) Cell Deficiency during Chronic Graft-Versus-Host Disease Is Improved By Low-Dose IL-2 Therapy Blood. 130: 4439-4439. DOI: 10.1182/Blood.V130.Suppl_1.4439.4439 |
0.458 |
|
| 2017 |
Xing Y, Stefanski H, Bruce DW, Hippen KL, Coghill JM, McKinnon K, Reisdorf S, Blazar B, Serody JS. A Novel Process for the Expansion of Functional Human ILC2 Cells for GCHD Prevention Blood. 130: 4432-4432. DOI: 10.1182/Blood.V130.Suppl_1.4432.4432 |
0.451 |
|
| 2017 |
Lazaryan A, Lee SJ, Salhotra A, Jagasia M, Essell J, Zanin-Zhorov A, Gillivray BM, Schueller O, Eiznhamer D, Blazar B, Ryan JL. Initial Results of KD025-208: A Phase 2a Open Label Trial of KD025 for Steroid-Dependent Chronic Graft Versus Host Disease Blood. 130: 3256-3256. DOI: 10.1182/Blood.V130.Suppl_1.3256.3256 |
0.359 |
|
| 2017 |
Romee R, Cooley S, Berrien-Elliott M, Westervelt P, Verneris MR, Wagner JE, Weisdorf DJ, Blazar B, DiPersio JF, Cashen AF, Jeng EK, Rock A, Wong HC, Fehniger TA, Miller JS. First-in-Human Clinical Trial of the IL-15 Super-Agonist Complex ALT-803 for Patients Relapsed after Allogeneic Hematopoietic Cell Transplantation Blood. 130: 274-274. DOI: 10.1182/Blood.V130.Suppl_1.274.274 |
0.523 |
|
| 2017 |
Watkins B, Qayed M, Bratrude B, Betz K, Brown M, Rhodes J, Sinclair S, Suessmuth Y, Yu A, Hebert K, Pasquini MC, Choi SW, Davis J, Duncan C, Giller R, ... ... Blazar B, et al. T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival Blood. 130: 212-212. DOI: 10.1182/Blood.V130.Suppl_1.212.212 |
0.451 |
|
| 2017 |
Bjordahl R, Cichocki F, Clarke R, Gaidarova S, Groff B, Rogers P, Moreno S, Abujarour R, Bonello G, Lee T, Lan W, Bauer M, Robbins D, Rezner B, Cooley S, ... ... Blazar B, et al. Abstract 3755: Renewable and genetically engineered natural killer cells for off-the-shelf adoptive cellular immunotherapy Cancer Research. 77: 3755-3755. DOI: 10.1158/1538-7445.Am2017-3755 |
0.423 |
|
| 2017 |
Cichocki F, Valamehr B, Bjordahl R, Zhang B, Sarhan D, Cooley S, Blazar B, Rezner B, Rogers P, Green C, Abbot S, Shoemaker D, Wolchko S, Miller JS. Abstract 3752: FATE-NK100: A novel NK cell-mediated cancer therapy Cancer Research. 77: 3752-3752. DOI: 10.1158/1538-7445.Am2017-3752 |
0.456 |
|
| 2017 |
Dwyer GK, Mathews LR, Lucas A, Blazar BR, Turnquist HR. The “Type 2” Cytokine, Interlukin-33, Generates Potent CD4 + ST2 + Tbet + Th1 Responses Independently of IL-12 under Lymphopenic Conditions Transplantation. 101: S61. DOI: 10.1097/01.Tp.0000520395.84839.40 |
0.337 |
|
| 2017 |
Liu W, Guan X, Creemers JW, Pesu M, Urban JF, Kaplan M, Elliott DE, Blazar BR, Ince MN. A Two-Step Model - Involving Transcription Factor STAT6 and the Endopeptidase Furin - for the Development of TGFÎ'-Generating T Helper 3 (Th3) Cells and Regulation of Colitis Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)30652-2 |
0.4 |
|
| 2017 |
Hook K, Tolar J, McGrath J, Osborn M, Keene D, Riddle M, Hordinsky M, Marinkovich M, Tryon R, DeFor T, Ebens C, Tamai K, Hovnanian A, Blazar B, Wagner J. 308 Bone marrow/cord blood transplantation (BMCBT) ameliorates symptoms in some, but not all, subtypes of severe generalized junctional epidermolysis bullosa (JEB) Journal of Investigative Dermatology. 137. DOI: 10.1016/J.Jid.2017.02.324 |
0.63 |
|
| 2017 |
Zheng P, You X, Tamaresis J, Xu L, Hsu K, Than R, Iliopoulou BP, Pierini A, Schneidawind D, Zehnder JL, Blazar BR, Negrin RS, Meyer E. Repertoire of Murine T Cells in Target Tissues of MHC-Matched and -Mismatched Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 23: S307-S308. DOI: 10.1016/J.Bbmt.2016.12.230 |
0.459 |
|
| 2017 |
Tkachev V, Furlan SN, Watkins BK, Zheng H(, Hunt D, Panoskaltsis-Mortari A, Betz K, Brown M, Zeleski K, Yu A, Blazar BR, Casson D, Kirby I, Bland-Ward P, Kean LS. A Novel Therapeutic Strategy to Control Conventional T-Cells While Supporting Treg Reconstitution Post-Transplant: Long-Term GVHD-Free Survival by Combining OX40L Blockade with Rapamycin Biology of Blood and Marrow Transplantation. 23. DOI: 10.1016/J.Bbmt.2016.12.004 |
0.459 |
|
| 2016 |
Zeiser R, Blazar BR. Erratum: Preclinical models of acute and chronic graft-versus-host disease: How predictive are they for a successful clinical translation? (Blood (2016) 127:25 (3117-3126)) Blood. 128. PMID 31265502 DOI: 10.1182/Blood-2016-07-730580 |
0.313 |
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| 2016 |
Webber BR, Osborn MJ, McElroy AN, Twaroski K, Lonetree CL, DeFeo AP, Xia L, Eide C, Lees CJ, McElmurry RT, Riddle MJ, Kim CJ, Patel DD, Blazar BR, Tolar J. CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa. Npj Regenerative Medicine. 1. PMID 28250968 DOI: 10.1038/Npjregenmed.2016.14 |
0.813 |
|
| 2016 |
Astuti Y, Kramer AC, Blake AL, Blazar BR, Tolar J, Taisto ME, Lund TC. A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing. Stem Cell Reports. PMID 28041876 DOI: 10.1016/J.Stemcr.2016.12.004 |
0.454 |
|
| 2016 |
Bunting MD, Varelias A, Souza-Fonseca-Guimaraes F, Schuster IS, Lineburg KE, Kuns RD, Fleming P, Locke KR, Huntington ND, Blazar BR, Lane SW, Tey SK, MacDonald KP, Smyth MJ, Degli-Esposti MA, et al. GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity. Blood. PMID 27927647 DOI: 10.1182/Blood-2016-08-734020 |
0.505 |
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| 2016 |
McKenna DH, Sumstad D, Kadidlo DM, Batdorf B, Lord CJ, Merkel SC, Koellner CM, Curtsinger JM, June CH, Riley JL, Levine BL, Miller JS, Brunstein CG, Wagner JE, Blazar BR, et al. Optimization of cGMP purification and expansion of umbilical cord blood-derived T-regulatory cells in support of first-in-human clinical trials. Cytotherapy. PMID 27887864 DOI: 10.1016/J.Jcyt.2016.10.011 |
0.481 |
|
| 2016 |
He F, Verneris MR, Cooley S, Blazar BR, MacMillan ML, Newell LF, Panoskaltsis-Mortari A, DeFor T, Weisdorf DJ, Holtan SG. Low day +100 serum epidermal growth factor levels are associated with acute GvHD after allogeneic hematopoietic cell transplantation. Bone Marrow Transplantation. PMID 27869812 DOI: 10.1038/Bmt.2016.261 |
0.384 |
|
| 2016 |
Hippen KL, Watkins B, Tkachev V, Lemire AM, Lehnen C, Riddle MJ, Singh K, Panoskaltsis-Mortari A, Vanhove B, Tolar J, Kean LS, Blazar BR. Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease. Transplantation. 100: 2630-2639. PMID 27861291 DOI: 10.1097/Tp.0000000000001465 |
0.474 |
|
| 2016 |
MacDonald KP, Hill GR, Blazar BR. Chronic graft-versus-host disease: biological insights from pre-clinical and clinical studies. Blood. PMID 27821504 DOI: 10.1182/Blood-2016-06-686618 |
0.542 |
|
| 2016 |
Hirakawa M, Matos T, Liu H, Koreth J, Kim HT, Paul NE, Murase K, Whangbo J, Alho AC, Nikiforow S, Cutler C, Ho VT, Armand P, Alyea EP, Antin JH, ... Blazar BR, et al. Low-dose IL-2 selectively activates subsets of CD4(+) Tregs and NK cells. Jci Insight. 1: e89278. PMID 27812545 DOI: 10.1172/Jci.Insight.89278 |
0.474 |
|
| 2016 |
Furlan SN, Watkins B, Tkachev V, Cooley S, Panoskaltsis-Mortari A, Betz K, Brown M, Hunt DJ, Schell JB, Zeleski K, Yu A, Giver C, Waller E, Miller JS, Blazar BR, et al. Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and man. Blood. PMID 27758873 DOI: 10.1182/Blood-2016-07-726547 |
0.492 |
|
| 2016 |
Osborn MJ, Webber BR, McElmurry RT, Rudser KD, DeFeo AP, Muradian M, Petryk A, Hallgrimsson B, Blazar BR, Tolar J, Braunlin EA. Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathology. Journal of Inherited Metabolic Disease. PMID 27743312 DOI: 10.1007/S10545-016-9988-Z |
0.745 |
|
| 2016 |
Cooke KR, Luznik L, Sarantopoulos S, Hakim FT, Jagasia M, Fowler DH, van den Brink MR, Hansen JA, Parkman R, Miklos DB, Martin PJ, Paczesny S, Vogelsang G, Pavletic S, Ritz J, ... ... Blazar BR, et al. The Biology of Chronic Graft-Versus-Host Disease: a Task Force Report From the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-Versus-Host Disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 27713092 DOI: 10.1016/J.Bbmt.2016.09.023 |
0.358 |
|
| 2016 |
Le Texier L, Lineburg KE, Cao B, McDonald-Hyman C, Leveque-El Mouttie L, Nicholls J, Melino M, Nalkurthi BC, Alexander KA, Teal B, Blake SJ, Souza-Fonseca-Guimaraes F, Engwerda CR, Kuns RD, Lane SW, ... ... Blazar BR, et al. Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease. Jci Insight. 1: e86850. PMID 27699243 DOI: 10.1172/Jci.Insight.86850 |
0.537 |
|
| 2016 |
Li JM, Petersen CT, Li J, Panjwani R, Chandra DJ, Giver CR, Blazar BR, Waller EK. Modulation of Immune Checkpoints and Graft-versus-Leukemia in Allogeneic Transplants by Vasoactive Intestinal Peptide. Cancer Research. PMID 27671676 DOI: 10.1158/0008-5472.Can-16-0427 |
0.568 |
|
| 2016 |
Zeiser R, Socié G, Blazar BR. Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation. British Journal of Haematology. PMID 27619472 DOI: 10.1111/Bjh.14295 |
0.549 |
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| 2016 |
Hippen KL, Watkins B, Tkachev V, Lemire AM, Lehnen C, Riddle MJ, Singh K, Panoskaltsis-Mortari A, Vanhove B, Tolar J, Kean LS, Blazar BR. Preclinical testing of anti-human CD28 Fab' antibody in a novel nonhuman primate (NHP) small animal rodent model of xenogenic graft-versus-host disease (GVHD). Transplantation. PMID 27607527 DOI: 10.1097/TP.0000000000001465 |
0.348 |
|
| 2016 |
Bejanyan N, Rogosheske J, DeFor TE, Lazaryan A, Arora M, Holtan SG, Jacobson PA, MacMillan ML, Verneris MR, Blazar BR, Weisdorf DJ, Wagner JE, Brunstein CG. Sirolimus and Mycophenolate Mofetil as Calcineurin Inhibitor-Free GVHD Prophylaxis for RIC Umbilical Cord Blood Transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 27519278 DOI: 10.1016/J.Bbmt.2016.08.005 |
0.395 |
|
| 2016 |
Sarhan D, Cichocki F, Zhang B, Yingst A, Spellman SR, Cooley S, Verneris MR, Blazar BR, Miller JS. Adaptive NK cells with low TIGIT expression are inherently resistant to myeloid-derived suppressor cells. Cancer Research. PMID 27503932 DOI: 10.1158/0008-5472.Can-16-0839 |
0.439 |
|
| 2016 |
Zheng HB, Watkins B, Tkachev V, Yu S, Tran D, Furlan S, Zeleski K, Singh K, Hamby K, Hotchkiss C, Lane J, Gumber S, Adams A, Cendales L, Kirk AD, ... ... Blazar BR, et al. The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism But With A Significant Risk of CMV Reactivation and Disease in Rhesus Macaques. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27500470 DOI: 10.1111/Ajt.14006 |
0.51 |
|
| 2016 |
Murali AR, Chandra S, Stewart Z, Blazar BR, Farooq U, Ince MN, Dunkelberg J. Graft versus Host Disease After Liver Transplantation in Adults: A Case series, Review of Literature, and an Approach to Management. Transplantation. PMID 27495762 DOI: 10.1097/Tp.0000000000001406 |
0.329 |
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| 2016 |
Lu Y, Hippen KL, Lemire AL, Gu J, Wang W, Ni X, Ranganathan P, Levine BL, Riley JL, June CH, Turka LA, Munn DH, Garzon R, Lu L, Blazar BR. miR-146b antagomir treated human Tregs increase TRAF6-NFkB expression, suppressor function and GVHD inhibitory potency. Blood. PMID 27485827 DOI: 10.1182/Blood-2016-05-714535 |
0.345 |
|
| 2016 |
Ding ZC, Liu C, Cao Y, Habtetsion T, Kuczma M, Pi W, Kong H, Cacan E, Greer SF, Cui Y, Blazar BR, Munn DH, Zhou G. IL-7 signaling imparts polyfunctionality and stemness potential to CD4(+) T cells. Oncoimmunology. 5: e1171445. PMID 27471650 DOI: 10.1080/2162402X.2016.1171445 |
0.518 |
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| 2016 |
D'Alincourt Salazar M, Manuel ER, Tsai W, D'Apuzzo M, Goldstein L, Blazar BR, Diamond DJ. Evaluation of innate and adaptive immunity contributing to the antitumor effects of PD1 blockade in an orthotopic murine model of pancreatic cancer. Oncoimmunology. 5: e1160184. PMID 27471630 DOI: 10.1080/2162402X.2016.1160184 |
0.348 |
|
| 2016 |
Weiss JM, Chen W, Nyuydzefe MS, Trzeciak A, Flynn R, Tonra JR, Marusic S, Blazar BR, Waksal SD, Zanin-Zhorov A. ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings. Science Signaling. 9: ra73. PMID 27436361 DOI: 10.1126/Scisignal.Aad8953 |
0.766 |
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| 2016 |
McDonald-Hyman C, Flynn R, Panoskaltsis-Mortari A, Peterson N, MacDonald KP, Hill GR, Luznik L, Serody JS, Murphy WJ, Maillard I, Munn DH, Turka LA, Koreth J, Cutler CS, Soiffer RJ, ... ... Blazar BR, et al. Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5 dependent manner. Blood. PMID 27385791 DOI: 10.1182/Blood-2016-05-715896 |
0.764 |
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| 2016 |
Leveque-El Mouttie L, Koyama M, Le Texier L, Markey KA, Cheong M, Kuns RD, Lineburg KE, Teal BE, Alexander KA, Clouston AD, Blazar BR, Hill GR, MacDonald KP. Corruption of dendritic cell antigen presentation during acute GVHD leads to a failure of regulatory T-cell homeostasis and chronic GVHD. Blood. PMID 27338097 DOI: 10.1182/Blood-2015-11-680876 |
0.473 |
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| 2016 |
Brinkman CC, Iwami D, Hritzo MK, Xiong Y, Ahmad S, Simon T, Hippen KL, Blazar BR, Bromberg JS. Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration. Nature Communications. 7: 12021. PMID 27323847 DOI: 10.1038/Ncomms12021 |
0.501 |
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| 2016 |
Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, ... ... Blazar BR, et al. Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. The Journal of Clinical Investigation. PMID 27294527 DOI: 10.1172/Jci85796 |
0.424 |
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| 2016 |
Zanin-Zhorov A, Flynn R, Waksal SD, Blazar BR. Isoform-specific targeting of ROCK proteins in immune cells. Small Gtpases. 0. PMID 27254302 DOI: 10.1080/21541248.2016.1181698 |
0.696 |
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| 2016 |
Matta BM, Reichenbach DK, Blazar BR, Turnquist HR. Alarmins and their receptors as modulators and indicators of alloimmune responses. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27232285 DOI: 10.1111/Ajt.13887 |
0.398 |
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| 2016 |
Matta BM, Reichenbach DK, Zhang X, Mathews L, Koehn BH, Dwyer GK, Lott JM, Uhl FM, Pfeifer D, Feser CJ, Smith MJ, Liu Q, Zeiser R, Blazar BR, Turnquist HR. Peri-alloHCT IL-33 administration expands recipient T regulatory cells that protect mice against acute GVHD. Blood. PMID 27222477 DOI: 10.1182/Blood-2015-12-684142 |
0.437 |
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| 2016 |
Li W, Liu L, Gomez A, Zhang J, Ramadan A, Zhang Q, Choi SW, Zhang P, Greenson JK, Liu C, Jiang D, Virts E, Kelich SL, Chu HW, Flynn R, ... Blazar BR, et al. Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease. Jci Insight. 1. PMID 27195312 DOI: 10.1172/Jci.Insight.86660 |
0.76 |
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| 2016 |
Wang H, Hou L, Kwak D, Fassett J, Xu X, Chen A, Chen W, Blazar BR, Xu Y, Hall JL, Ge JB, Bache RJ, Chen Y. Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression. Hypertension. PMID 27160197 DOI: 10.1161/Hypertensionaha.116.07084 |
0.419 |
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| 2016 |
Mochizuki K, Meng L, Mochizuki I, Tong Q, He S, Liu Y, Purushe J, Fung H, Zaidi MR, Zhang Y, Reshef R, Blazar BR, Yagita H, Mineishi S, Zhang Y. Programming of donor T cells using allogeneic delta-like ligand 4-positive dendritic cells to reduce GVHD in mice. Blood. PMID 27143255 DOI: 10.1182/Blood-2015-05-644476 |
0.572 |
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| 2016 |
Borges CM, Reichenbach DK, Kim BS, Misra A, Blazar BR, Turka LA. T Regulatory Cell Expressed Myd88 Is Critical For Prolongation Of Allograft Survival. Transplant International : Official Journal of the European Society For Organ Transplantation. PMID 27112509 DOI: 10.1111/Tri.12788 |
0.555 |
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| 2016 |
Koreth J, Kim HT, Jones KT, Lange PB, Reynolds CG, Chammas MJ, Dusenbury K, Whangbo J, Nikiforow S, Alyea EP, Armand P, Cutler CS, Ho VT, Chen YB, Avigan D, ... Blazar BR, et al. Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft vs. host disease. Blood. PMID 27073224 DOI: 10.1182/Blood-2016-02-702852 |
0.419 |
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| 2016 |
Mehta RS, Peffault de Latour R, DeFor TE, Robin M, Lazaryan A, Xhaard A, Bejanyan N, de Fontbrune FS, Arora M, Brunstein CG, Blazar BR, Weisdorf DJ, MacMillan ML, Socie G, Holtan SG. Improved graft-versus-host disease-free, relapse-free survival associated with bone marrow as the stem cell source in adults. Haematologica. PMID 27036159 DOI: 10.3324/Haematol.2015.138990 |
0.419 |
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| 2016 |
Zeiser R, Blazar BR. Preclinical models of acute and chronic graft-versus-host disease: how predictive are they for a successful clinical translation? Blood. PMID 26994149 DOI: 10.1182/Blood-2016-02-699082 |
0.427 |
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| 2016 |
Flynn R, Paz K, Du J, Reichenbach DK, Taylor PA, Panoskaltsis-Mortari A, Vulic A, Luznik L, MacDonald KK, Hill GR, Nyuydzefe MS, Weiss JM, Chen W, Trzeciak A, Serody JS, ... ... Blazar BR, et al. Targeted Rho-associated kinase 2 (ROCK2) inhibition decreases clinical and immune pathology of murine and human chronic GVHD through Stat3-dependent mechanism. Blood. PMID 26983850 DOI: 10.1182/Blood-2015-10-678706 |
0.751 |
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| 2016 |
Forcade E, Kim HT, Cutler C, Wang K, Alho AC, Nikiforow S, Ho VT, Koreth J, Armand P, Alyea EP, Blazar BR, Soiffer RJ, Antin JH, Ritz J. Circulating T follicular helper cells with increased function during chronic graft-versus-host-disease. Blood. PMID 26944544 DOI: 10.1182/Blood-2015-12-688895 |
0.532 |
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| 2016 |
Vallera DA, Felices M, McElmurry RT, McCullar V, Zhou X, Schmohl J, Zhang B, Lenvik A, Panoskaltsis-Mortari A, Verneris MR, Tolar J, Cooley S, Weisdorf D, Blazar BR, Miller JS. IL-15 Trispecific Killer Engagers (TriKEs) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing In Vivo Expansion, and Enhanced Function. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26847056 DOI: 10.1158/1078-0432.Ccr-15-2710 |
0.43 |
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| 2016 |
Schönle A, Hartl FA, Mentzel J, Nöltner T, Rauch KS, Prestipino A, Wohlfeil SA, Apostolova P, Hechinger AK, Melchinger W, Fehrenbach K, Guadamillas MC, Follo M, Prinz G, Ruess AK, ... ... Blazar BR, et al. Caveolin-1 regulates TCR signal strength and regulatory T cell differentiation into alloreactive T cells. Blood. PMID 26837700 DOI: 10.1182/Blood-2015-09-672428 |
0.543 |
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| 2016 |
Knorr DA, Wang H, Aurora M, MacMillan ML, Holton SG, Bergerson R, Cao Q, Weisdorf DJ, Cooley S, Brunstein C, Miller JS, Wagner JE, Blazar BR, Verneris MR. Loss of T Follicular Helper Cells In the Peripheral Blood Of Patients With Chronic Graft vs. Host Disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 26806586 DOI: 10.1016/J.Bbmt.2016.01.003 |
0.555 |
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| 2016 |
Osborn MJ, Webber BR, Knipping F, Lonetree CL, Tennis N, DeFeo AP, McElroy AN, Starker CG, Lee C, Merkel S, Lund TC, Kelly-Spratt KS, Jensen MC, Voytas DF, von Kalle C, ... ... Blazar BR, et al. Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 570-81. PMID 26502778 DOI: 10.1038/Mt.2015.197 |
0.829 |
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| 2016 |
Ince MN, Blazar BR, Edmond MB, Tricot G, Wannemuehler MJ. Understanding Luminal Microorganisms and Their Potential Effectiveness in Treating Intestinal Inflammation. Inflammatory Bowel Diseases. 22: 194-201. PMID 26457381 DOI: 10.1097/Mib.0000000000000599 |
0.423 |
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| 2016 |
Miklos D, Cutler CS, Arora M, Waller EK, Jagasia M, Pusic I, Flowers ME, Logan AC, Nakamura R, Blazar BR, Li Y, Lal I, Dubovsky J, James DF, Styles L, et al. Multicenter Open-Label Phase 2 Study of Ibrutinib in Chronic Graft Versus Host Disease (cGVHD) after Failure of Corticosteroids Blood. 128: LBA-3-LBA-3. DOI: 10.1182/Blood.V128.22.Lba-3.Lba-3 |
0.317 |
|
| 2016 |
Sinha RK, Flynn RP, Fernandez JA, Xu X, Martin G, Kupriyanov S, Griffin JH, Blazar BR. Activated Protein C (APC) Therapy Ameliorates Chronic Graft Versus Host Disease By Cell Signaling Mechanisms That Require Cleavage at Arg46 in PAR1 on T Cells Blood. 128: 808-808. DOI: 10.1182/Blood.V128.22.808.808 |
0.742 |
|
| 2016 |
Radojcic V, Flynn RP, Chung J, Du J, Perkey E, Paz K, Zaiken M, Friedman A, Yan M, Siebel CW, Blazar BR, Maillard I. Notch Signaling Mediated By Dll1/4 Notch Ligands Controls the Pathogenesis of Both Multi-Organ System Non-Sclerodermatous and Sclerodermatous Chronic Graft-Versus-Host Disease Blood. 128: 805-805. DOI: 10.1182/Blood.V128.22.805.805 |
0.794 |
|
| 2016 |
Newell LF, DeFor TE, Cutler CS, Verneris MR, Blazar BR, Antin JH, Howard A, Wu J, MacMillan ML, Panoskaltsis-Mortari A, Weisdorf DJ, Holtan SG. Follistatin and Endoglin: Potential Biomarkers of Endothelial Damage and Non-Relapse Mortality after Myeloablative Allogeneic Hematopoietic Cell Transplantation in Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 0402 Blood. 128: 63-63. DOI: 10.1182/Blood.V128.22.63.63 |
0.371 |
|
| 2016 |
Felices M, Lenvik A, Chu S, McElmurry R, Cooley S, Tolar J, Blazar BR, Miller JS. Continuous IL-15 Signaling Leads to Functional Exhaustion of Human Natural Killer Cells through Metabolic Changes That Alters Their In Vivo Anti-Tumor Activity Blood. 128: 551-551. DOI: 10.1182/Blood.V128.22.551.551 |
0.37 |
|
| 2016 |
Koreth J, Kim HT, Lange PB, Armand P, Cutler CS, Ho VT, Glotzbecker B, Yusuf RZ, Nikiforow S, Dey BR, McMasters M, Ritz J, Blazar BR, Soiffer RJ, Antin JH, et al. Bortezomib-Based Versus Standard of Care Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation: A Phase II Randomized Controlled Trial Blood. 128: 508-508. DOI: 10.1182/Blood.V128.22.508.508 |
0.367 |
|
| 2016 |
Williams R, Cooley S, Bachanova V, Waldmann TA, Blazar BR, Weisdorf DJ, Miller JS, Verneris MR. Role of Recipient CD8+ T Cell Exhaustion in the Rejection of Adoptively Transferred Haploidentical NK Cells Blood. 128: 503-503. DOI: 10.1182/Blood.V128.22.503.503 |
0.529 |
|
| 2016 |
Bejanyan N, Brunstein CG, Cao Q, Mehta RS, Luo X, Curtsinger J, Cooley S, Blazar BR, Miller JS, Weisdorf D, Wagner JE, Verneris MR. Immune Reconstitution (IR) after Allogeneic Hematopoietic Cell Transplantation (alloHCT): Comparing Results in Recipients of Unrelated Umbilical Cord Blood (UCB) to Those with an HLA-Matched Sibling Donor Peripheral Blood (MSD PB) Blood. 128: 4590-4590. DOI: 10.1182/Blood.V128.22.4590.4590 |
0.518 |
|
| 2016 |
Zeiser R, Burchert A, Lengerke C, Verbeek M, Maas-Bauer K, Metzelder S, Spoerl S, Ditschkowski M, Ecsedi M, Sockel K, Ayuk F, Salem A, Fontbrune FSd, Na I, Livius P, ... ... Blazar BR, et al. Long-Term Follow-up of Patients with Corticosteroid-Refractory Graft-Versus-Host Disease Treated with Ruxolitinib Blood. 128: 4561-4561. DOI: 10.1182/Blood.V128.22.4561.4561 |
0.641 |
|
| 2016 |
Galvez Silva J, Mendt Vilchez M, Nobuhiko I, Blazar BR, Zweidler-McKay P, Rezvani K, Shpall EJ. Ex-Vivo Fucosylation Improves the Anti-Graft-Versus-Host-Disease Effects of Mesenchymal Stem Cells in the NOD/SCID/IL-2R Null Mouse Model Blood. 128: 4559-4559. DOI: 10.1182/Blood.V128.22.4559.4559 |
0.444 |
|
| 2016 |
Wu Y, Schutt SD, Flynn RP, Zhang M, Nguyen HD, Blazar BR, Yu X. MiR-17-92 Is Required for the Pathogenicity of T and B Cells in Chronic Gvhd Blood. 128: 4535-4535. DOI: 10.1182/Blood.V128.22.4535.4535 |
0.719 |
|
| 2016 |
Thangavelu G, Saha A, Aoyama K, McDonald-Hyman C, Lee Y, Brown C, Panoskaltsis-Mortari A, Osborn MJ, Chandraratna RA, Noelle R, Blazar BR. Critical Roles of Retinoic Acid Signaling in Combating Acute Graft Versus Host Disease Blood. 128: 4534-4534. DOI: 10.1182/Blood.V128.22.4534.4534 |
0.711 |
|
| 2016 |
Felices M, Sarhan D, Brandt L, Guldevall K, McElmurry R, Lenvik A, Chu S, Tolar J, Taras E, Spellman SR, Warlick ED, Verneris MR, Cooley S, Weisdorf D, Blazar BR, et al. CD16-IL15-CD33 Trispecific Killer Engager (TriKE) Overcomes Cancer-Induced Immune Suppression and Induces Natural Killer Cell-Mediated Control of MDS and AML Via Enhanced Killing Kinetics Blood. 128: 4291-4291. DOI: 10.1182/Blood.V128.22.4291.4291 |
0.395 |
|
| 2016 |
Tkachev V, Furlan SN, Watkins B, Zheng B, Hunt D, Panoskaltsis-Mortari A, Betz K, Brown M, Zeleski K, Yu A, Blazar BR, Casson D, Kirby I, Bland-Ward P, Kean L. Striking Clinical, Molecular and Immunological Outcomes in Non-Human Primate Hematopoietic Stem Cell Transplantation Using a Novel OX40L Blockade Agent, KY1005, Combined with Rapamycin Blood. 128: 3341-3341. DOI: 10.1182/Blood.V128.22.3341.3341 |
0.548 |
|
| 2016 |
Bachanova V, Sarhan D, DeFor TE, Cooley S, Panoskaltsis-Mortari A, Verneris MR, Blazar BR, Curtsinger J, Burns LJ, Weisdorf DJ, Miller JS. Haploidentical Natural Killer Cell Infusion Induces Remission in Non-Hodgkin Lymphoma and Overcomes Resistance to Rituximab Blood. 128: 3030-3030. DOI: 10.1182/Blood.V128.22.3030.3030 |
0.445 |
|
| 2016 |
Mehta RS, Bejanyan N, Cao Q, Luo X, Brunstein C, Cooley S, Blazar BR, Weisdorf DJ, Wagner JE, Miller JS, Verneris MR. Immune Reconstitution after Umbilical Cord Blood Versus Peripheral Blood Progenitor Cell Transplantation in Adults Following Myeloablative Conditioning Blood. 128: 2246-2246. DOI: 10.1182/Blood.V128.22.2246.2246 |
0.446 |
|
| 2016 |
Turcotte LM, Cao Q, Krahn E, Curtsinger J, Yingst AM, Cooley S, Brunstein CG, MacMillan ML, Holtan SG, Wagner JE, Weisdorf DJ, Blazar BR, Miller JS, Verneris MR. Monocyte Subpopulation Recovery and Outcomes Following Hematopoietic Cell Transplantation Blood. 128: 2232-2232. DOI: 10.1182/Blood.V128.22.2232.2232 |
0.431 |
|
| 2016 |
Hippen KL, MacMillan ML, Lemire A, Saha A, Hanse E, Lord C, Kelekar A, O'Connor RS, Riley JL, June CH, Kean L, Miller JS, Wagner JE, Munn DH, Blazar BR. In Vitro Induction of Human Regulatory T-Cells (iTregs) Using Conditions of Low Tryptophan Plus Kynurenines Blood. 128: 1229-1229. DOI: 10.1182/blood.v128.22.1229.1229 |
0.362 |
|
| 2016 |
Cichocki F, Valamehr B, Sarhan D, Zhang B, Cooley S, Verneris MR, Blazar BR, Bjordahl R, Rezner B, Rogers P, Green C, McKenna DH, Shoemaker D, Wolchko S, Miller JS. Development and Scale-up of a Novel GMP Method for Enrichment and Expansion of Terminally Differentiated Adaptive Natural Killer Cells (FATE-NK100) with Enhanced Anti-Tumor Function Blood. 128: 1225-1225. DOI: 10.1182/Blood.V128.22.1225.1225 |
0.489 |
|
| 2016 |
Du J, Flynn RP, Paz K, Vulic A, Robinson TM, Lineburg KE, Macdonald KPA, Hill GR, Serody JS, Maillard I, Panoskaltsis-Mortari A, Schacker T, Luznik L, Blazar BR. Pirfenidone Reverses Murine Chronic Graft Versus Host Disease Blood. 128: 1158-1158. DOI: 10.1182/Blood.V128.22.1158.1158 |
0.719 |
|
| 2016 |
Bruce DW, Stefanski HE, Vincent BG, Dant T, Reisdorf S, Bommiasamy H, Serody D, Wilson JE, McKinnon K, Shlomchik WD, Armistead PM, Ting JP, Woosley JT, Zaiss DM, Blazar BR, et al. Mechanism and Activity of ILC2 Cells Post Allo-BMT Blood. 128: 1155-1155. DOI: 10.1182/Blood.V128.22.1155.1155 |
0.54 |
|
| 2016 |
Salazar Md, Manuel E, Tsai W, D'Apuzzo M, Goldstein L, Blazar BR, Diamond DJ. Abstract B170: Blockade of checkpoint programmed death 1 (PD1) delays tumor growth and induces early transferable protective immunity in a murine orthotopic pancreatic ductal adenocarcinoma model Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B170 |
0.372 |
|
| 2016 |
Zhang J, Ramadan A, Griesenauer B, Li W, Turner M, Kapur R, Hanenberg H, Paczesny S, Liu C, Blazar B, Tawara I. Id: 91: St2 Blockade Reduces Sst2-Producing T Cells While Maintaining Protective Mst2-Expressing T Cells During Graft-Versus-Host Disease Journal of Investigative Medicine. 64: 946-947. DOI: 10.1136/Jim-2016-000120.69 |
0.545 |
|
| 2016 |
Li Y, Chen H, Weiner GJ, Kaplan MH, Elliott DE, Blazar BR, Ince MN. Tu1874 The Recipient STAT6 Pathway Is Critical in Helminth-Induced Intestinal Immune Regulation and Mitigation of Graft-Versus-Host Disease (GVHD) Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33268-1 |
0.375 |
|
| 2016 |
Li Y, Chen H, Weiner GJ, Blumberg RS, Blazar BR, Elliott DE, Ince MN. 191 Interleukin 4 Is Critical in Helminth-Induced Regulatory T-Cell Expansion and Suppression of Colitis in a Graft Versus Host Disease Model Gastroenterology. 150: S50. DOI: 10.1016/S0016-5085(16)30292-X |
0.493 |
|
| 2016 |
Osborn M, Webber B, McElroy A, Defeo A, Patel D, Lees C, McElmurry R, Riddle M, Blazar B, Tolar J. 371 CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa (RDEB) Journal of Investigative Dermatology. 136: S66. DOI: 10.1016/J.Jid.2016.02.404 |
0.724 |
|
| 2016 |
Bejanyan N, Rogosheske J, Defor TE, Holtan S, Jacobson P, MacMillan ML, Verneris MR, Arora M, Lazaryan A, Blazar BR, Weisdorf DJ, Wagner JE, Brunstein CG. Sirolimus/Mycophenolate Mofetil (MMF): Effective Calcineurin Inhibitor-Free GVHD Prophylaxis for Reduced Intensity Conditioning (RIC) Umbilical Cord Blood (UCB) Transplantation Biology of Blood and Marrow Transplantation. 22. DOI: 10.1016/J.Bbmt.2015.11.771 |
0.338 |
|
| 2016 |
Mathew NR, Baumgartner F, Waterhouse M, Müller TA, Schmitt-Gräff A, Weber A, Osswald L, Hanke K, Solsona ST, Spath S, Pfeifer D, Follo M, Claus R, Lübbert M, Rummelt C, ... ... Blazar BR, et al. Sorafenib Promotes Graft-Versus-Leukemia Activity in Mice and Humans through IL-15 Production in Leukemia Cells Biology of Blood and Marrow Transplantation. 22. DOI: 10.1016/J.Bbmt.2015.11.389 |
0.416 |
|
| 2016 |
Newell LF, Verneris MR, Panoskaltsis-Mortari A, Defor TE, Blazar BR, Cutler CS, Antin JH, MacMillan ML, Weisdorf DJ, Holtan S. Angiogenic Factors, Inflammation, and Outcomes in Myeloablative Allogeneic Hematopoietic Cell Transplantation: A Biomarker Analysis of Gvhd Prophylaxis in Blood and Marrow Transplant Clinical Trials Network Protocol (BMT CTN) 0402 Biology of Blood and Marrow Transplantation. 22. DOI: 10.1016/J.Bbmt.2015.11.363 |
0.391 |
|
| 2016 |
Mehta RS, deLatour RP, Defor TE, Robin M, Lazaryan A, Xhaard A, Bejanyan N, Fontbrune FSd, Arora M, Brunstein CG, Blazar BR, Weisdorf DJ, MacMillan ML, Socié G, Holtan S. Improved Graft-Versus-Host Disease-Free, Relapse-Free Survival (GRFS) Associated with Bone Marrow as the Stem Cell Source in Adults Biology of Blood and Marrow Transplantation. 22. DOI: 10.1016/J.Bbmt.2015.11.334 |
0.371 |
|
| 2015 |
Omer AK, Weisdorf DJ, Lazaryan A, Shanley R, Blazar BR, MacMillan ML, Brunstein C, Bejanyan N, Arora M. Late Acute Graft Versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 26743342 DOI: 10.1016/J.Bbmt.2015.12.020 |
0.349 |
|
| 2015 |
Wagner JE, Brunstein CG, Boitano AE, DeFor TE, McKenna D, Sumstad D, Blazar BR, Tolar J, Le C, Jones J, Cooke MP, Bleul CC. Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft. Cell Stem Cell. PMID 26669897 DOI: 10.1016/J.Stem.2015.10.004 |
0.469 |
|
| 2015 |
Furlan SN, Watkins B, Tkachev V, Flynn R, Cooley S, Ramakrishnan S, Singh K, Giver C, Hamby K, Stempora L, Garrett A, Chen J, Betz KM, Ziegler CG, Tharp GK, ... ... Blazar BR, et al. Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention. Science Translational Medicine. 7: 315ra191. PMID 26606970 DOI: 10.1126/Scitranslmed.Aad3231 |
0.789 |
|
| 2015 |
Sharma MD, Shinde R, McGaha TL, Huang L, Holmgaard RB, Wolchok JD, Mautino MR, Celis E, Sharpe AH, Francisco LM, Powell JD, Yagita H, Mellor AL, Blazar BR, Munn DH. The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment. Science Advances. 1: e1500845. PMID 26601142 DOI: 10.1126/Sciadv.1500845 |
0.375 |
|
| 2015 |
Koehn BH, Zeiser R, Blazar BR. Inflammasome effects in GvHD. Oncotarget. 6: 38444-5. PMID 26564963 DOI: 10.18632/Oncotarget.6307 |
0.505 |
|
| 2015 |
Brunstein CG, Miller JS, McKenna DH, Hippen KL, DeFor TE, Sumstad D, Curtsinger J, Verneris MR, MacMillan ML, Levine BL, Riley JI, June CH, Le C, Weisdorf D, McGlave PB, ... Blazar BR, et al. Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile and clinical effect. Blood. PMID 26563133 DOI: 10.1182/Blood-2015-06-653667 |
0.464 |
|
| 2015 |
Zhang J, Ramadan AM, Griesenauer B, Li W, Turner MJ, Liu C, Kapur R, Hanenberg H, Blazar BR, Tawara I, Paczesny S. ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease. Science Translational Medicine. 7: 308ra160. PMID 26446957 DOI: 10.1126/Scitranslmed.Aab0166 |
0.546 |
|
| 2015 |
Brunstein CG, Petersdorf EW, DeFor TE, Noreen H, Maurer D, MacMillan ML, Ustun C, Verneris MR, Miller JS, Blazar BR, McGlave PB, Weisdorf DJ, Wagner JE. Impact of Allele-Level HLA Mismatch on Outcomes in Recipients of Double Umbilical Cord Blood Transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 26431630 DOI: 10.1016/J.Bbmt.2015.09.025 |
0.352 |
|
| 2015 |
Sckisel GD, Mirsoian A, Bouchlaka MN, Tietze JK, Chen M, Blazar BR, Murphy WJ. Late administration of murine CTLA-4 blockade prolongs CD8-mediated anti-tumor effects following stimulatory cancer immunotherapy. Cancer Immunology, Immunotherapy : Cii. PMID 26423422 DOI: 10.1007/S00262-015-1759-4 |
0.454 |
|
| 2015 |
Cichocki F, Cooley S, Davis Z, DeFor TE, Schlums H, Zhang B, Brunstein CG, Blazar BR, Wagner J, Diamond DJ, Verneris MR, Bryceson YT, Weisdorf DJ, Miller JS. CD56(dim)CD57(+)NKG2C(+) NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT. Leukemia. PMID 26416461 DOI: 10.1038/Leu.2015.260 |
0.484 |
|
| 2015 |
Lazaryan A, Weisdorf DJ, DeFor T, Brunstein CG, MacMillan ML, Bejanyan N, Holtan S, Blazar BR, Wagner JE, Arora M. Risk Factors for Acute and Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation with Umbilical Cord Blood and Matched Related Donors. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 26365153 DOI: 10.1016/J.Bbmt.2015.09.008 |
0.399 |
|
| 2015 |
Koehn BH, Apostolova P, Haverkamp JM, Miller JS, McCullar V, Tolar J, Munn DH, Murphy WJ, Brickey WJ, Serody JS, Gabrilovich DI, Bronte V, Murray PJ, Ting JP, Zeiser R, ... Blazar BR, et al. GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. Blood. 126: 1621-8. PMID 26265697 DOI: 10.1182/Blood-2015-03-634691 |
0.454 |
|
| 2015 |
Sckisel GD, Bouchlaka MN, Monjazeb AM, Crittenden M, Curti BD, Wilkins DE, Alderson KA, Sungur CM, Ames E, Mirsoian A, Reddy A, Alexander W, Soulika A, Blazar BR, Longo DL, et al. Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity. Immunity. 43: 240-50. PMID 26231116 DOI: 10.1016/J.Immuni.2015.06.023 |
0.499 |
|
| 2015 |
Zeiser R, Burchert A, Lengerke C, Verbeek M, Maas-Bauer K, Metzelder SK, Spoerl S, Ditschkowski M, Ecsedi M, Sockel K, Ayuk F, Ajib S, de Fontbrune FS, Na IK, Penter L, ... ... Blazar BR, et al. Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey. Leukemia. 29: 2062-8. PMID 26228813 DOI: 10.1038/Leu.2015.212 |
0.697 |
|
| 2015 |
Smith MJ, Webber BR, Mohtashami M, Stefanski HE, Zún˜iga-Pflücker JC, Blazar BR. Concise Review: In Vitro T-Cell Generation from Adult, Embryonic, and Induced Pluripotent Stem Cells: Many Roads to One Destination. Stem Cells (Dayton, Ohio). PMID 26227158 DOI: 10.1002/Stem.2115 |
0.783 |
|
| 2015 |
Davis ZB, Cooley SA, Cichocki F, Felices M, Wangen R, Luo X, DeFor TE, Bryceson YT, Diamond DJ, Brunstein C, Blazar BR, Wagner JE, Weisdorf DJ, Horowitz A, Guethlein LA, et al. Adaptive Natural Killer Cell and Killer Cell Immunoglobulin-Like Receptor-Expressing T Cell Responses are Induced by Cytomegalovirus and Are Associated with Protection against Cytomegalovirus Reactivation after Allogeneic Donor Hematopoietic Cell Transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 26055301 DOI: 10.1016/J.Bbmt.2015.05.025 |
0.549 |
|
| 2015 |
Koreth J, Kim HT, Lange PB, Bindra B, Reynolds CG, Chammas MJ, Armand P, Cutler CS, Ho VT, Glotzbecker B, Nikiforow S, Ritz J, Blazar BR, Soiffer RJ, Antin JH, et al. A Bortezomib-based Regimen Offers Promising Survival and Graft-vs.-Host Disease Prophylaxis in Myeloablative HLA-Mismatched and Unrelated Donor Transplantation: A Phase II Trial. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 26055298 DOI: 10.1016/J.Bbmt.2015.05.027 |
0.434 |
|
| 2015 |
Ahn YO, Weeres MA, Neulen ML, Choi J, Kang SH, Heo DS, Bergerson R, Blazar BR, Miller JS, Verneris MR. Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation. European Journal of Immunology. PMID 26046454 DOI: 10.1002/Eji.201445213 |
0.327 |
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| 2015 |
Cichocki F, Verneris MR, Cooley S, Bachanova V, Brunstein CG, Blazar BR, Wagner J, Schlums H, Bryceson YT, Weisdorf DJ, Miller JS. The Past, Present, and Future of NK Cells in Hematopoietic Cell Transplantation and Adoptive Transfer. Current Topics in Microbiology and Immunology. PMID 26037048 DOI: 10.1007/82_2015_445 |
0.467 |
|
| 2015 |
Flynn R, Allen JL, Luznik L, MacDonald KP, Paz K, Alexander KA, Vulic A, Du J, Panoskaltsis-Mortari A, Taylor PA, Poe JC, Serody JS, Murphy WJ, Hill GR, Maillard I, ... ... Blazar BR, et al. Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease. Blood. 125: 4085-94. PMID 25852057 DOI: 10.1182/Blood-2014-08-595470 |
0.752 |
|
| 2015 |
Suessmuth Y, Mukherjee R, Watkins B, Koura DT, Finstermeier K, Desmarais C, Stempora L, Horan JT, Langston A, Qayed M, Khoury HJ, Grizzle A, Cheeseman JA, Conger JA, Robertson J, ... ... Blazar BR, et al. CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire. Blood. 125: 3835-50. PMID 25852054 DOI: 10.1182/Blood-2015-03-631853 |
0.522 |
|
| 2015 |
MacMillan ML, DeFor TE, Young JA, Dusenbery KE, Blazar BR, Slungaard A, Zierhut H, Weisdorf DJ, Wagner JE. Alternative donor hematopoietic cell transplantation for Fanconi anemia. Blood. 125: 3798-804. PMID 25824692 DOI: 10.1182/Blood-2015-02-626002 |
0.421 |
|
| 2015 |
Reichenbach DK, Schwarze V, Matta BM, Tkachev V, Lieberknecht E, Liu Q, Koehn BH, Pfeifer D, Taylor PA, Prinz G, Dierbach H, Stickel N, Beck Y, Warncke M, Junt T, ... ... Blazar BR, et al. The IL-33/ST2 axis augments effector T-cell responses during acute GVHD. Blood. 125: 3183-92. PMID 25814531 DOI: 10.1182/Blood-2014-10-606830 |
0.488 |
|
| 2015 |
Veenstra RG, Flynn R, Kreymborg K, McDonald-Hyman C, Saha A, Taylor PA, Osborn MJ, Panoskaltsis-Mortari A, Schmitt-Graeff A, Lieberknect E, Murphy WJ, Serody JS, Munn DH, Freeman GJ, Allison JP, ... ... Blazar BR, et al. B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality. Blood. 125: 3335-46. PMID 25814530 DOI: 10.1182/Blood-2014-09-603357 |
0.829 |
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| 2015 |
McDonald-Hyman C, Turka LA, Blazar BR. Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation. Science Translational Medicine. 7: 280rv2. PMID 25810312 DOI: 10.1126/Scitranslmed.Aaa6853 |
0.402 |
|
| 2015 |
Pauken KE, Nelson CE, Martinov T, Spanier JA, Heffernan JR, Sahli NL, Quarnstrom CF, Osum KC, Schenkel JM, Jenkins MK, Blazar BR, Vezys V, Fife BT. Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade. Journal of Immunology (Baltimore, Md. : 1950). 194: 3551-5. PMID 25769925 DOI: 10.4049/Jimmunol.1402262 |
0.374 |
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| 2015 |
Blazar BR, Flynn R, Lee R, Marcucci G, Caliguiri MA, Heeger PS. Strategies to inhibit alloantibody production in alloprimed murine recipients of hematopoietic stem cell grafts. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15: 931-41. PMID 25762193 DOI: 10.1111/Ajt.13125 |
0.77 |
|
| 2015 |
Holtan SG, Verneris MR, Schultz KR, Newell LF, Meyers G, He F, DeFor TE, Vercellotti GM, Slungaard A, MacMillan ML, Cooley SA, Blazar BR, Panoskaltsis-Mortari A, Weisdorf DJ. Circulating angiogenic factors associated with response and survival in patients with acute graft-versus-host disease: results from Blood and Marrow Transplant Clinical Trials Network 0302 and 0802. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 21: 1029-36. PMID 25759146 DOI: 10.1016/J.Bbmt.2015.02.018 |
0.331 |
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| 2015 |
Multhaup MM, Podetz-Pedersen KM, Karlen AD, Olson ER, Gunther R, Somia NV, Blazar BR, Cowan MJ, McIvor RS. Role of transgene regulation in ex vivo lentiviral correction of artemis deficiency. Human Gene Therapy. 26: 232-43. PMID 25738323 DOI: 10.1089/Hum.2014.062 |
0.469 |
|
| 2015 |
Varelias A, Gartlan KH, Kreijveld E, Olver SD, Lor M, Kuns RD, Lineburg KE, Teal BE, Raffelt NC, Cheong M, Alexander KA, Koyama M, Markey KA, Sturgeon E, Leach J, ... ... Blazar BR, et al. Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation. Blood. 125: 2435-44. PMID 25673640 DOI: 10.1182/Blood-2014-07-590232 |
0.414 |
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| 2015 |
Hoseini SS, Hapke M, Herbst J, Wedekind D, Baumann R, Heinz N, Schiedlmeier B, Vignali DA, van den Brink MR, Schambach A, Blazar BR, Sauer MG. Inducible T-cell receptor expression in precursor T cells for leukemia control. Leukemia. 29: 1530-42. PMID 25652739 DOI: 10.1038/Leu.2015.20 |
0.543 |
|
| 2015 |
Sarantopoulos S, Blazar BR, Cutler C, Ritz J. Reprint of: B cells in chronic graft-versus-host disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 21: S11-8. PMID 25620647 DOI: 10.1016/J.Bbmt.2014.12.033 |
0.489 |
|
| 2015 |
Holtan SG, DeFor TE, Lazaryan A, Bejanyan N, Arora M, Brunstein CG, Blazar BR, MacMillan ML, Weisdorf DJ. Composite end point of graft-versus-host disease-free, relapse-free survival after allogeneic hematopoietic cell transplantation. Blood. 125: 1333-8. PMID 25593335 DOI: 10.1182/Blood-2014-10-609032 |
0.424 |
|
| 2015 |
MacMillan ML, Robin M, Harris AC, DeFor TE, Martin PJ, Alousi A, Ho VT, Bolaños-Meade J, Ferrara JL, Jones R, Arora M, Blazar BR, Holtan SG, Jacobsohn D, Pasquini M, et al. A refined risk score for acute graft-versus-host disease that predicts response to initial therapy, survival, and transplant-related mortality. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 21: 761-7. PMID 25585275 DOI: 10.1016/J.Bbmt.2015.01.001 |
0.338 |
|
| 2015 |
Osborn MJ, Gabriel R, Webber BR, DeFeo AP, McElroy AN, Jarjour J, Starker CG, Wagner JE, Joung JK, Voytas DF, von Kalle C, Schmidt M, Blazar BR, Tolar J. Fanconi anemia gene editing by the CRISPR/Cas9 system. Human Gene Therapy. 26: 114-26. PMID 25545896 DOI: 10.1089/Hum.2014.111 |
0.751 |
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| 2015 |
Li Y, Chen HL, Bannick N, Henry M, Holm AN, Metwali A, Urban JF, Rothman PB, Weiner GJ, Blazar BR, Elliott DE, Ince MN. Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice. Journal of Immunology (Baltimore, Md. : 1950). 194: 1011-20. PMID 25527786 DOI: 10.4049/Jimmunol.1303099 |
0.519 |
|
| 2015 |
Sarantopoulos S, Blazar BR, Cutler C, Ritz J. B cells in chronic graft-versus-host disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 21: 16-23. PMID 25452031 DOI: 10.1016/J.Bbmt.2014.10.029 |
0.489 |
|
| 2015 |
Parmar S, Liu X, Najjar A, Shah N, Yang H, Yvon E, Rezvani K, McNiece I, Zweidler-McKay P, Miller L, Wolpe S, Blazar BR, Shpall EJ. Ex vivo fucosylation of third-party human regulatory T cells enhances anti-graft-versus-host disease potency in vivo. Blood. 125: 1502-6. PMID 25428215 DOI: 10.1182/Blood-2014-10-603449 |
0.484 |
|
| 2015 |
Hechinger AK, Smith BA, Flynn R, Hanke K, McDonald-Hyman C, Taylor PA, Pfeifer D, Hackanson B, Leonhardt F, Prinz G, Dierbach H, Schmitt-Graeff A, Kovarik J, Blazar BR, Zeiser R. Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD. Blood. 125: 570-80. PMID 25352130 DOI: 10.1182/Blood-2014-06-581793 |
0.727 |
|
| 2015 |
Sharma M, Shinde R, McGaha T, Huang L, Holmgaard R, Wolchok J, Mautino M, Celis E, Sharpe A, Francisco L, Powell J, Yagita H, Mellor A, Blazar B, Munn D. The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells Journal For Immunotherapy of Cancer. 3: O19. DOI: 10.1186/2051-1426-3-S2-O19 |
0.447 |
|
| 2015 |
Blazar BR, O'Connor RS, Milone MC, Dustin ML, Riley JL, Vincent BG, Serody JS, Flynn RP, Paz K, Du J, Panoskaltsis-Mortari A, Jeffrey M, Ahmed R, Turka LAA, Freeman GJ, et al. Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease Blood. 126: SCI-8-SCI-8. DOI: 10.1182/Blood.V126.23.Sci-8.Sci-8 |
0.682 |
|
| 2015 |
Forcade E, Kim HT, Cutler CS, Wang KS, Ho VT, Koreth J, Armand P, Alyea EP, Blazar BR, Soiffer RJ, Antin JH, Ritz J. Activated Circulating T Follicular Helper Cells with Increased Function during Chronic Graft Versus Host Disease after Allogeneic Stem Cell Transplantation Blood. 126: 924-924. DOI: 10.1182/Blood.V126.23.924.924 |
0.518 |
|
| 2015 |
Zeiser R, Burchert A, Lengerke C, Verbeek M, Maas-Bauer K, Metzelder S, Spoerl S, Ditschkowski M, Ecsedi M, Sockel K, Ayuk F, Ajib S, Sicre de Fontbrune F, Na I, Penter L, ... ... Blazar BR, et al. Treatment of Corticosteroid-Refractory Graft-Versus-Host Disease with Ruxolitinib in 95 Patients Blood. 126: 858-858. DOI: 10.1182/Blood.V126.23.858.858 |
0.689 |
|
| 2015 |
McDonald-Hyman C, Thangavelu G, Muller J, Zhang G, Kumari S, Saha A, Koehn BH, Mitchell JS, Fife BT, Serody JS, Osborn MJ, Hippen KL, Kelekar A, Munn DH, Altman A, ... ... Blazar BR, et al. Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function Blood. 126: 849-849. DOI: 10.1182/Blood.V126.23.849.849 |
0.723 |
|
| 2015 |
Miller JS, Verneris MR, Curtsinger J, DeFor TE, McKenna D, Waldmann TA, Blazar BR, Weisdorf DJ, Cooley S. A Phase I Study of Intravenous NCI IL-15 to Enhance Adoptively Transferred NK Cells Uncovers Defects in CD16 Triggered IFNγ Production and Competition Between Donor NK and Recipient T Cells Blood. 126: 566-566. DOI: 10.1182/Blood.V126.23.566.566 |
0.484 |
|
| 2015 |
Tolar J, McGrath JA, Osborn MJ, Keene DR, Hook K, Hordinsky M, Woodley D, Chen M, Hovnanian A, Tamai K, Blazar BR, Wagner JE. Mucocutaneous Engraftment and Type VII Collagen (C7) Replacement after Allogeneic Hematopoietic Cell Transplantation (HCT) in Patients with Recessive Dystrophic Epidermolysis Bullosa (RDEB) Blood. 126: 402-402. DOI: 10.1182/Blood.V126.23.402.402 |
0.679 |
|
| 2015 |
Zitzer NC, Taylor PA, Ngankeu A, Efebera YA, Devine SM, Blazar BR, Garzon R, Ranganathan P. MiR-155 Impacts T Cell Migration in Acute Graft-Versus-Host Disease (aGVHD) Blood. 126: 3080-3080. DOI: 10.1182/Blood.V126.23.3080.3080 |
0.437 |
|
| 2015 |
Tkachev V, Furlan SN, Watkins B, Panoskaltsis-Mortari A, Blazar BR, Kean L. T Stem Cell Memory Dynamics during Acute Graft-Versus-Host Disease Blood. 126: 3079-3079. DOI: 10.1182/Blood.V126.23.3079.3079 |
0.53 |
|
| 2015 |
Mochizuki K, Meng L, Mochizuki I, Tong Q, He S, Liu Y, Purushe J, Sun H, Fung H, Zaidi R, Reshef R, Blazar BR, Yagita H, Mineishi S, Zhang Y. Programming of Donor T Cells Using Allogeneic Delta-like Ligand 4-Positive Dendritic Cells to Reduce Gvhd but Retain GVL Activity Blood. 126: 233-233. DOI: 10.1182/Blood.V126.23.233.233 |
0.573 |
|
| 2015 |
Miller JS, Felice M, McElmurry R, McCullar V, Zhou X, Tolar J, Schmohl JU, Panoskaltsis-Mortari A, Zhang B, Taras E, Verneris MR, Cooley S, Weisdorf DJ, Blazar BR, Vallera D. Trispecific Killer Engagers (TriKEs) that contain IL-15 to make NK cells antigen specific and to sustain their persistence and expansion Blood. 126: 232-232. DOI: 10.1182/Blood.V126.23.232.232 |
0.459 |
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| 2015 |
Frank C, Zhang B, Felice M, Blazar BR, Miller JS. mTORC1 Signaling and Metabolism Are Dynamically Regulated during Human NK Cell Maturation and in Adaptive NK Cell Responses to Viral Infection Blood. 126: 209-209. DOI: 10.1182/Blood.V126.23.209.209 |
0.445 |
|
| 2015 |
Osborn MJ, Webber BR, Knipping F, Lonetree C, DeFeo A, McElroy A, Starker C, Gabriel R, Merkel S, Hippen KL, Voytas D, von Kalle C, Schmidt M, Miller JS, Jarjour J, ... ... Blazar BR, et al. Megatal, Crispr/Cas9, and Talen T-Cell Receptor Gene Editing Blood. 126: 2045-2045. DOI: 10.1182/Blood.V126.23.2045.2045 |
0.815 |
|
| 2015 |
Miller JS, Cooley S, Holtan S, Arora M, Ustun C, Jeng E, Wong HC, Verneris MR, Wagner JE, Weisdorf DJ, Blazar BR, Fehniger TA, Romee R. 'First-in-human' phase I dose escalation trial of IL-15N72D/IL-15Rα-Fc superagonist complex (ALT-803) demonstrates immune activation with anti-tumor activity in patients with relapsed hematological malignancy Blood. 126: 1957-1957. DOI: 10.1182/Blood.V126.23.1957.1957 |
0.455 |
|
| 2015 |
Abu Shanap MS, Cooley S, Luo X, Qing C, Curtsinger J, Bergerson R, Bejanyan N, Stefanski H, Brunstein C, Weisdorf DJ, Blazar BR, Miller JS, Wagner JE, Verneris MR. Defining Successful Immune Reconstitution (IR) after Allogeneic Hematopoietic Cell Transplantation (HCT) Blood. 126: 1934-1934. DOI: 10.1182/Blood.V126.23.1934.1934 |
0.469 |
|
| 2015 |
Kolupaev O, West M, Blazar BR, Tilley S, Coghill J, Serody JS. Chronic GvHD Is Characterized By Impaired B Cell Development in the Bone Marrow Blood. 126: 1883-1883. DOI: 10.1182/Blood.V126.23.1883.1883 |
0.511 |
|
| 2015 |
Furlan SN, Tkachev V, Watkins B, Betz K, Panoskaltsis-Mortari A, Blazar BR, Kean L. Th17/Th22 Cells Mediate Breakthrough Graft-Versus-Host-Disease Blood. 126: 1878-1878. DOI: 10.1182/Blood.V126.23.1878.1878 |
0.523 |
|
| 2015 |
Li J, Petersen CT, Li J, Giver CR, Blazar BR, Waller EK. Blocking VIP Signaling during Allogeneic Bone Marrow Transplantation Separates the Graft Versus Leukemia from Graft Versus Host Disease Activity of Donor CD8 T-Cells Blood. 126: 1877-1877. DOI: 10.1182/Blood.V126.23.1877.1877 |
0.532 |
|
| 2015 |
Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Burrill JS, Guo L, Sacristan C, Furlan SN, ... ... Blazar BR, et al. Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality Blood. 126: 147-147. DOI: 10.1182/Blood.V126.23.147.147 |
0.451 |
|
| 2015 |
Zeiser R, Burchert A, Lengerke C, Verbeek M, Maas-Bauer K, Metzelder SK, Spoerl S, Ditschkowski M, Ecsedi M, Sockel K, Ayuk F, Ajib S, de Fontbrune FS, Na IK, Penter L, ... ... Blazar BR, et al. Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey Leukemia. DOI: 10.1038/leu.2015.212 |
0.683 |
|
| 2015 |
Webber BR, Tolar J, Kyba M, Blazar BR. Targeted single copy Runx1 reporter lines for interrogation and enhancement of definitive hematopoiesis from murine pluripotent stem cells Experimental Hematology. 43: S100. DOI: 10.1016/J.Exphem.2015.06.278 |
0.69 |
|
| 2015 |
Radojcic V, Chung J, Friedman A, Reddy P, Blazar BR, Luznik L, Brennan T, Siebel C, Maillard I. Early Post-Transplant Notch Signaling Activity Is Critical for the Differentiation of Pathogenic Alloantigen-Specific T Cells Mediating Acute Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 21. DOI: 10.1016/J.Bbmt.2014.11.553 |
0.375 |
|
| 2015 |
Omer A, Weisdorf DJ, Lazaryan A, Shanley R, Blazar BR, MacMillan ML, Brunstein C, Bejanyan N, Arora M. Late Onset Acute GVHD (late aGVHD) after Allogeneic Hematopoietic Stem Cell Transplantation (HCT) Biology of Blood and Marrow Transplantation. 21. DOI: 10.1016/J.Bbmt.2014.11.544 |
0.423 |
|
| 2015 |
Furlan SN, Watkins BK, Mortari A, Blazar BR, Kean LS. T-Cell Transcriptome Analysis Reveals the Mechanisms Controlling Synergy Between Costimulation Blockade and mTOR Inhibition during GVHD Prevention Biology of Blood and Marrow Transplantation. 21. DOI: 10.1016/J.Bbmt.2014.11.525 |
0.44 |
|
| 2015 |
Forcade E, Paula S, Cowens K, Bento ML, Nikiforow S, Koreth J, Cutler CS, Ho VT, Armand P, Alyea EP, Soiffer RJ, Antin JH, Blazar BR, Ritz J. Recovery of Circulating T-Follicular Helper Cells after Hematopoietic Stem Cell Transplantation Biology of Blood and Marrow Transplantation. 21. DOI: 10.1016/J.Bbmt.2014.11.240 |
0.403 |
|
| 2015 |
Suessmuth Y, Koura D, Finstermeier K, Desmarais C, Horan J, Langston A, Qayed M, Khoury HJ, Watkins BK, Robins H, Mukherjee R, Blazar BR, Waller EK, Mehta A, Kean LS. Exhaustive TCR Deep Sequencing Reveals That CMV Reactivation Fundamentally Resets Immune Reconstitution after Transplant and Results in Significant Deficits in the Effector Memory TCR Repertoire Biology of Blood and Marrow Transplantation. 21: S69-S70. DOI: 10.1016/J.Bbmt.2014.11.074 |
0.324 |
|
| 2015 |
Holtan S, Verneris MR, Schultz KR, Newell LF, Meyers G, He F, Defor TE, MacMillan ML, Cooley S, Blazar BR, Panoskaltsis-Mortari A, Weisdorf DJ. Prognostic Impact of Follistatin in Acute Graft-Versus-Host Disease: Results from BMT CTN 0302 and 0802 Biology of Blood and Marrow Transplantation. 21. DOI: 10.1016/J.Bbmt.2014.11.056 |
0.4 |
|
| 2015 |
Furlan SN, Watkins BK, Mortari A, Blazar BR, Giver C, Waller EK, Kean LS. Defining the Primate T Cell Transcriptome during GvHD: New Data Implicating Sonic Hedgehog and Aurora Kinase Pathways in GvHD Pathogenesis and Prevention Biology of Blood and Marrow Transplantation. 21: S56. DOI: 10.1016/J.Bbmt.2014.11.055 |
0.429 |
|
| 2015 |
Brunstein C, Hippen K, Defor TE, McKenna D, Curtsinger J, Sumstad D, Levine BL, June CH, Miller JS, Verneris MR, Blazar BR, Wagner JE. Prevention of Acute GVHD by Ex Vivo Expanded Umbilical Cord Blood Derived Regulatory T Cells (Treg) Biology of Blood and Marrow Transplantation. 21: S55-S56. DOI: 10.1016/J.Bbmt.2014.11.054 |
0.442 |
|
| 2014 |
Zanin-Zhorov A, Weiss JM, Nyuydzefe MS, Chen W, Scher JU, Mo R, Depoil D, Rao N, Liu B, Wei J, Lucas S, Koslow M, Roche M, Schueller O, Weiss S, ... ... Blazar BR, et al. Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 111: 16814-9. PMID 25385601 DOI: 10.1073/Pnas.1414189111 |
0.456 |
|
| 2014 |
Singh K, Stempora L, Harvey RD, Kirk AD, Larsen CP, Blazar BR, Kean LS. Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 2691-703. PMID 25359003 DOI: 10.1111/Ajt.12934 |
0.368 |
|
| 2014 |
Dubovsky JA, Flynn R, Du J, Harrington BK, Zhong Y, Kaffenberger B, Yang C, Towns WH, Lehman A, Johnson AJ, Muthusamy N, Devine SM, Jaglowski S, Serody JS, Murphy WJ, ... ... Blazar BR, et al. Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. The Journal of Clinical Investigation. 124: 4867-76. PMID 25271622 DOI: 10.1172/Jci75328 |
0.794 |
|
| 2014 |
Matta BM, Lott JM, Mathews LR, Liu Q, Rosborough BR, Blazar BR, Turnquist HR. IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 4010-20. PMID 25217167 DOI: 10.4049/Jimmunol.1400481 |
0.379 |
|
| 2014 |
Felices M, Ankarlo DE, Lenvik TR, Nelson HH, Blazar BR, Verneris MR, Miller JS. Notch signaling at later stages of NK cell development enhances KIR expression and functional maturation. Journal of Immunology (Baltimore, Md. : 1950). 193: 3344-54. PMID 25172483 DOI: 10.4049/Jimmunol.1400534 |
0.398 |
|
| 2014 |
Alexander KA, Flynn R, Lineburg KE, Kuns RD, Teal BE, Olver SD, Lor M, Raffelt NC, Koyama M, Leveque L, Le Texier L, Melino M, Markey KA, Varelias A, Engwerda C, ... ... Blazar BR, et al. CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease. The Journal of Clinical Investigation. 124: 4266-80. PMID 25157821 DOI: 10.1172/Jci75935 |
0.693 |
|
| 2014 |
Ganguly S, Ross DB, Panoskaltsis-Mortari A, Kanakry CG, Blazar BR, Levy RB, Luznik L. Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice. Blood. 124: 2131-41. PMID 25139358 DOI: 10.1182/Blood-2013-10-525873 |
0.558 |
|
| 2014 |
Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ. Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help. Plos One. 9: e102709. PMID 25119341 DOI: 10.1371/Journal.Pone.0102709 |
0.465 |
|
| 2014 |
Pai CC, Hsiao HH, Sun K, Chen M, Hagino T, Tellez J, Mall C, Blazar BR, Monjazeb A, Abedi M, Murphy WJ. Therapeutic benefit of bortezomib on acute graft-versus-host disease is tissue specific and is associated with interleukin-6 levels. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 1899-904. PMID 25064746 DOI: 10.1016/J.Bbmt.2014.07.022 |
0.508 |
|
| 2014 |
Herrera AF, Kim HT, Bindra B, Jones KT, Alyea EP, Armand P, Cutler CS, Ho VT, Nikiforow S, Blazar BR, Ritz J, Antin JH, Soiffer RJ, Koreth J. A phase II study of bortezomib plus prednisone for initial therapy of chronic graft-versus-host disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 1737-43. PMID 25017765 DOI: 10.1016/J.Bbmt.2014.06.040 |
0.35 |
|
| 2014 |
Pai CC, Chen M, Mirsoian A, Grossenbacher SK, Tellez J, Ames E, Sun K, Jagdeo J, Blazar BR, Murphy WJ, Abedi M. Treatment of chronic graft-versus-host disease with bortezomib. Blood. 124: 1677-88. PMID 25009225 DOI: 10.1182/Blood-2014-02-554279 |
0.473 |
|
| 2014 |
May SL, Zhou Q, Lewellen M, Carter CM, Coffey D, Highfill SL, Bucher CM, Matise I, Morse HC, O'Sullivan MG, Schutten M, Johnson C, Bellgrau D, Blazar BR, Modiano JF. Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis. Plos One. 9: e100629. PMID 24945807 DOI: 10.1371/Journal.Pone.0100629 |
0.733 |
|
| 2014 |
Lund TC, Patrinostro X, Kramer AC, Stadem P, Higgins LA, Markowski TW, Wroblewski MS, Lidke DS, Tolar J, Blazar BR. sdf1 Expression reveals a source of perivascular-derived mesenchymal stem cells in zebrafish. Stem Cells (Dayton, Ohio). 32: 2767-79. PMID 24905975 DOI: 10.1002/Stem.1758 |
0.386 |
|
| 2014 |
Zhang SL, Wang X, Manna S, Zlotoff DA, Bryson JL, Blazar BR, Bhandoola A. Chemokine treatment rescues profound T-lineage progenitor homing defect after bone marrow transplant conditioning in mice. Blood. 124: 296-304. PMID 24876562 DOI: 10.1182/Blood-2014-01-552794 |
0.471 |
|
| 2014 |
Murase K, Kim HT, Bascug OR, Kawano Y, Ryan J, Matsuoka K, Davids MS, Koreth J, Ho VT, Cutler C, Armand P, Alyea EP, Blazar BR, Antin JH, Soiffer RJ, et al. Increased mitochondrial apoptotic priming of human regulatory T cells after allogeneic hematopoietic stem cell transplantation. Haematologica. 99: 1499-508. PMID 24859877 DOI: 10.3324/Haematol.2014.104166 |
0.559 |
|
| 2014 |
Olin MR, Low W, McKenna DH, Haines SJ, Dahlheimer T, Nascene D, Gustafson MP, Dietz AB, Clark HB, Chen W, Blazar B, Ohlfest JR, Moertel C. Vaccination with dendritic cells loaded with allogeneic brain tumor cells for recurrent malignant brain tumors induces a CD4(+)IL17(+) response. Journal For Immunotherapy of Cancer. 2: 4. PMID 24829761 DOI: 10.1186/2051-1426-2-4 |
0.357 |
|
| 2014 |
Flynn R, Du J, Veenstra RG, Reichenbach DK, Panoskaltsis-Mortari A, Taylor PA, Freeman GJ, Serody JS, Murphy WJ, Munn DH, Sarantopoulos S, Luznik L, Maillard I, Koreth J, Cutler C, ... ... Blazar BR, et al. Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. Blood. 123: 3988-98. PMID 24820310 DOI: 10.1182/Blood-2014-03-562231 |
0.861 |
|
| 2014 |
Miller JS, Rooney CM, Curtsinger J, McElmurry R, McCullar V, Verneris MR, Lapteva N, McKenna D, Wagner JE, Blazar BR, Tolar J. Expansion and homing of adoptively transferred human natural killer cells in immunodeficient mice varies with product preparation and in vivo cytokine administration: implications for clinical therapy. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 1252-7. PMID 24816582 DOI: 10.1016/J.Bbmt.2014.05.004 |
0.403 |
|
| 2014 |
Ding ZC, Lu X, Yu M, Lemos H, Huang L, Chandler P, Liu K, Walters M, Krasinski A, Mack M, Blazar BR, Mellor AL, Munn DH, Zhou G. Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis. Cancer Research. 74: 3441-53. PMID 24780756 DOI: 10.1158/0008-5472.Can-13-3596 |
0.437 |
|
| 2014 |
Bachanova V, Cooley S, Defor TE, Verneris MR, Zhang B, McKenna DH, Curtsinger J, Panoskaltsis-Mortari A, Lewis D, Hippen K, McGlave P, Weisdorf DJ, Blazar BR, Miller JS. Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein. Blood. 123: 3855-63. PMID 24719405 DOI: 10.1182/Blood-2013-10-532531 |
0.439 |
|
| 2014 |
Gleason MK, Ross JA, Warlick ED, Lund TC, Verneris MR, Wiernik A, Spellman S, Haagenson MD, Lenvik AJ, Litzow MR, Epling-Burnette PK, Blazar BR, Weiner LM, Weisdorf DJ, Vallera DA, et al. CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets. Blood. 123: 3016-26. PMID 24652987 DOI: 10.1182/Blood-2013-10-533398 |
0.475 |
|
| 2014 |
Kaliyaperumal S, Watkins B, Sharma P, Furlan S, Ramakrishnan S, Giver C, Garcia A, Courtney C, Knight H, Strobert E, Elder E, Crenshaw T, Blazar BR, Waller EK, Westmoreland S, et al. CD8-predominant T-cell CNS infiltration accompanies GVHD in primates and is improved with immunoprophylaxis. Blood. 123: 1967-9. PMID 24652969 DOI: 10.1182/Blood-2014-01-547612 |
0.464 |
|
| 2014 |
Felices M, Lenvik TR, Ankarlo DE, Foley B, Curtsinger J, Luo X, Blazar BR, Anderson SK, Miller JS. Functional NK cell repertoires are maintained through IL-2Rα and Fas ligand. Journal of Immunology (Baltimore, Md. : 1950). 192: 3889-97. PMID 24634493 DOI: 10.4049/Jimmunol.1302601 |
0.405 |
|
| 2014 |
MacDonald KP, Le Texier L, Zhang P, Morris H, Kuns RD, Lineburg KE, Leveque L, Don AL, Markey KA, Vuckovic S, Bagger FO, Boyle GM, Blazar BR, Hill GR. Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10. Journal of Immunology (Baltimore, Md. : 1950). 192: 3180-9. PMID 24585878 DOI: 10.4049/Jimmunol.1302315 |
0.507 |
|
| 2014 |
Jacobson CA, Sun L, Kim HT, McDonough SM, Reynolds CG, Schowalter M, Koreth J, Cutler CS, Ho VT, Alyea EP, Armand P, Blazar BR, Soiffer RJ, Antin JH, Ritz J, et al. Post-transplantation B cell activating factor and B cell recovery before onset of chronic graft-versus-host disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 668-75. PMID 24462743 DOI: 10.1016/J.Bbmt.2014.01.021 |
0.458 |
|
| 2014 |
Lin KL, Fulton LM, Berginski M, West ML, Taylor NA, Moran TP, Coghill JM, Blazar BR, Bear JE, Serody JS. Intravital imaging of donor allogeneic effector and regulatory T cells with host dendritic cells during GVHD. Blood. 123: 1604-14. PMID 24415540 DOI: 10.1182/Blood-2013-09-526020 |
0.527 |
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| 2014 |
Tolar J, McGrath JA, Xia L, Riddle MJ, Lees CJ, Eide C, Keene DR, Liu L, Osborn MJ, Lund TC, Blazar BR, Wagner JE. Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa. The Journal of Investigative Dermatology. 134: 1246-54. PMID 24317394 DOI: 10.1038/Jid.2013.523 |
0.688 |
|
| 2014 |
Sawitzki B, Brunstein C, Meisel C, Schumann J, Vogt K, Appelt C, Curtsinger JM, Verneris MR, Miller JS, Wagner JE, Blazar BR. Prevention of graft-versus-host disease by adoptive T regulatory therapy is associated with active repression of peripheral blood Toll-like receptor 5 mRNA expression. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 173-82. PMID 24184334 DOI: 10.1016/J.Bbmt.2013.10.022 |
0.531 |
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| 2014 |
Rogosheske JR, Fargen AD, DeFor TE, Warlick E, Arora M, Blazar BR, Weisdorf DJ, Brunstein CG. Higher therapeutic CsA levels early post transplantation reduce risk of acute GVHD and improves survival. Bone Marrow Transplantation. 49: 122-5. PMID 24037024 DOI: 10.1038/Bmt.2013.139 |
0.348 |
|
| 2014 |
Sckisel GD, Tietze JK, Zamora AE, Hsiao HH, Priest SO, Wilkins DE, Lanier LL, Blazar BR, Baumgarth N, Murphy WJ. Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function. Clinical and Experimental Immunology. 175: 79-91. PMID 23937663 DOI: 10.1111/Cei.12186 |
0.443 |
|
| 2014 |
Reichenbach DK, Schwarze V, Matta BM, Tkachev V, Lieberknecht E, Liu Q, Koehn BH, Pfeifer D, Taylor PA, Prinz G, Dierbach H, Stickel N, Beck Y, Warncke M, Junt T, ... ... Blazar BR, et al. Regulation of Immune Responses during Acute GvHD Via the IL-33/ST2 Axis Blood. 124: 844-844. DOI: 10.1182/Blood.V124.21.844.844 |
0.464 |
|
| 2014 |
Chung J, Ebens CL, Radojcic V, Koch U, Friedman A, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Ludewig B, Siebel CW, Radtke F, Maillard I. Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease Blood. 124: 841-841. DOI: 10.1182/Blood.V124.21.841.841 |
0.585 |
|
| 2014 |
Cichocki F, Davis ZB, DeFor TE, Cooley SA, Bryceson YT, Diamond DJ, Blazar BR, Brunstein C, Wagner JE, Verneris MR, Weisdorf DJ, Miller JS. CMV Reactivation is Associated with Reduced Relapse Risk, Better Disease-Free Survival and Expansion of Adaptive NK Cells after Reduced Intensity Hematopoietic Cell Transplantation Blood. 124: 668-668. DOI: 10.1182/Blood.V124.21.668.668 |
0.469 |
|
| 2014 |
Hoseini SS, Hapke M, Herbst J, Wedekind D, Baumann R, Krueger A, Heinz N, Schiedlmeier B, Vignali D, van den Brink MR, Schambach A, Blazar BR, Sauer MG. Timely Controlled T Cell Receptor Expression of Genetically Engineered Precursor T Cells Requires Early Transgene Induction for Leukemia Control after Hematopoietic Stem Cell Transplantation Blood. 124: 657-657. DOI: 10.1182/Blood.V124.21.657.657 |
0.565 |
|
| 2014 |
Zanin-Zhorov A, Flynn R, Luznik L, Panoskaltsis-Mortari A, Jing D, Goodman K, Weiss J, Nyuydzefe M, Chen W, Serody JS, MacDonald KP, Hill GR, O'Shea J, Roche M, Weiss S, ... ... Blazar BR, et al. A Selective and Potent Rock 2 Inhibitor (KD025) Decreases Human STAT3-Dependent IL-21 and IL-17 Production and Experimental Chronic Graft-Versus-Host Disease (cGVHD) Blood. 124: 540-540. DOI: 10.1182/Blood.V124.21.540.540 |
0.75 |
|
| 2014 |
Bruce D, West M, Dant TA, Panoskaltsis-Mortari A, Blazar BR, Coghill JM, Serody JS. Infusion of Ex Vivo Activated Donor Type 2 Innate Lymphoid Cells Inhibit Th1 Activity and Reduces Acute Graft-Versus-Host Disease Blood. 124: 538-538. DOI: 10.1182/Blood.V124.21.538.538 |
0.573 |
|
| 2014 |
Flynn RP, Goodman K, Qi J, Jing D, Panoskaltsis-Mortari A, Yi Z, Dong C, Liu X, MacDonald KPA, Hill GR, Serody JS, Murphy WJ, Luznik L, Maillard I, Koreth J, ... ... Blazar BR, et al. Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies Blood. 124: 535-535. DOI: 10.1182/Blood.V124.21.535.535 |
0.771 |
|
| 2014 |
Mirsoian A, Bouchlaka MN, Sckisel G, Chen M, Pai CS, Maverakis E, Spencer R, Fishbein K, Siddiqui S, Monjazeb A, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, ... Blazar BR, et al. Adiposity As a Principal Component of Lethal Cytokine Storm Following Cancer Immunotherapy in Aged Mice Blood. 124: 460-460. DOI: 10.1182/Blood.V124.21.460.460 |
0.305 |
|
| 2014 |
Holtan SG, DeFor TE, Lazaryan A, Bejanyan N, Arora M, Blazar BR, MacMillan ML, Weisdorf DJ. What Predicts Success for a New Composite Endpoint: Graft–versus-Host Disease-Free and Relapse-Free Survival (GRFS) after Allogeneic Hematopoietic Cell Transplantation? Blood. 124: 429-429. DOI: 10.1182/Blood.V124.21.429.429 |
0.41 |
|
| 2014 |
Knorr DA, Nelson RW, Shanley R, Karras N, Miller JS, Wagner JE, Blazar BR, Verneris MR. Stem Cell Source Dependent Differences in Reconstituting Peripheral T Follicular Helper Cells Following Hematopoietic Cell Transplantation, Their Association with Chronic Gvhd and Role in Response to Influenza Vaccination Blood. 124: 3919-3919. DOI: 10.1182/Blood.V124.21.3919.3919 |
0.47 |
|
| 2014 |
He FC, Verneris MR, Cooley SA, Blazar BR, MacMillan ML, Panoskaltsis-Mortari A, Weisdorf DJ, Holtan SG. Relationship of Epidermal Growth Factor to Cyclosporine-Assocated Magnesium Wasting and Clinical Outcomes Post-Allogeneic Hematopoietic Cell Transplantation Blood. 124: 3914-3914. DOI: 10.1182/Blood.V124.21.3914.3914 |
0.385 |
|
| 2014 |
Furlan SN, Watkins B, Hanby K, Garrett AP, Panoskaltsis-Mortari A, Blazar BR, Kean LS. T-Cell Transcriptome Analysis Reveals the Mechanisms Controlling Synergy Between Costimulation Blockade and mTOR Inhibition during Graft Versus Host Disease Prevention Blood. 124: 3824-3824. DOI: 10.1182/Blood.V124.21.3824.3824 |
0.526 |
|
| 2014 |
Furlan SN, Watkins B, Flynn RP, Ramakrishnan S, Singh K, Giver CR, Hanby K, Stempora L, Garrett AP, Ziegler CG, Tharp G, Bosinger S, Blazar BR, Waller EK, Kean LS. Defining the Primate T Cell Transcriptome during Graft Versus Host Disease: New Data Implicating the Hedgehog and Aurora Kinase Pathways in Pathogenesis and Prevention Blood. 124: 2432-2432. DOI: 10.1182/Blood.V124.21.2432.2432 |
0.768 |
|
| 2014 |
Lazaryan A, DeFor TE, Brunstein C, MacMillan ML, Bejanyan N, Holtan SG, Blazar BR, Wagner JE, Weisdorf DJ, Arora M. Risk Factors for Acute and Chronic Gvhd after Allogeneic Hematopoietic Cell Transplantation (allo-HCT): Relative Risks with Umbilical Cord Blood (UCB) and Matched Related Donors (MRD) Blood. 124: 189-189. DOI: 10.1182/Blood.V124.21.189.189 |
0.425 |
|
| 2014 |
MacMillan ML, Robin M, Harris AC, Defor TE, Martin PJ, Alousi A, Ho VT, Bolanos-Meade J, Ferrara JL, Jones RJ, Arora M, Blazar BR, Holtan SG, Jacobsohn D, Pasquini MC, et al. A Refined Clinical Risk Score at Onset of Treatment for Acute Gvhd That Predicts Response to Initial Therapy, Survival and Transplant-Related Mortality Blood. 124: 188-188. DOI: 10.1182/Blood.V124.21.188.188 |
0.306 |
|
| 2014 |
Davis ZB, Cichocki F, Felices M, Wangen R, DeFor TE, Cooley SA, Bryceson YT, Diamond DJ, Brunstein C, Blazar BR, Wagner JE, Weisdorf DJ, Horowitz A, Guethlein LA, Parham P, et al. Clonal Expansion of Adaptive NK Cells and NKG2C+CD57+ KIR-Expressing T Cells from Sibling, but Not Umbilical Cord Blood, Grafts Is Induced By Recipient Latent CMV and Is Associated with Protection Against CMV Reactivation Blood. 124: 181-181. DOI: 10.1182/Blood.V124.21.181.181 |
0.473 |
|
| 2014 |
Li Y, Chen H, Bannick N, Henry MD, Elliott DE, Weiner GJ, Blazar BR, Ince MN. Intestinal Helminth Colonization Regulates Lethal Graft Versus Host Disease and Preserves Graft Versus Tumor in Bone Marrow Transplanted Mice Blood. 124: 1102-1102. DOI: 10.1182/Blood.V124.21.1102.1102 |
0.529 |
|
| 2014 |
Dubovsky JA, Flynn R, Du J, Harrington BK, Zhong Y, Yang C, Towns W, Lehman A, Johnson A, Devine S, Jaglowski S, Serody JS, Murphy WJ, Munn DH, Luznik L, ... ... Blazar BR, et al. Abstract 2591: Ibrutinib can reverse established chronic graft-versus-host disease, which is dependent upon IL-2 inducible T-cell kinase (ITK) and Bruton's tyrosine kinase (BTK)-driven lymphocyte activation Cancer Research. 74: 2591-2591. DOI: 10.1158/1538-7445.Am2014-2591 |
0.769 |
|
| 2014 |
Matta B, Lott J, Mathews L, Rosborough B, Blazar B, Turnquist H. IL-33 Promotes Selective Expansion of ST2+Foxp3+ Regulatory T Cells Dependent On Dendritic Cell Secretion of IL-2. Transplantation. 98: 291. DOI: 10.1097/00007890-201407151-00909 |
0.41 |
|
| 2014 |
Li Y, Chen H, Elliott DE, Urban JF, Blazar BR, Ince MN. Sa1772 The Transcription Factor STAT6 Is Required for Mucosal TGFβ Generating T Cell (TH3) Induction and Intestinal Immune Regulation Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)61043-X |
0.402 |
|
| 2014 |
Varelias A, Gartlan KH, Kreijveld E, Olver SD, Lor M, Kuns RD, Lineburg KE, Teal BE, Raffelt NC, Cheong M, Alexander KA, Koyama M, Markey KA, Sturgeon E, Leach J, ... ... Blazar BR, et al. 188: Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation Cytokine. 70: 73-73. DOI: 10.1016/J.Cyto.2014.07.195 |
0.409 |
|
| 2014 |
Kaliyaperumal S, Sharma P, Watkins BK, Furlan SN, Ramakrishnan S, Giver C, Garcia A, Courtney C, Hamby K, Garrett A, Deane T, Strobert E, Jenkins J, Elder E, Eishiavielli N, ... ... Blazar BR, et al. CD8-Predominant T Cell Meningitis Accompanies Gvhd in Primates and Is Prevented with Immunoprophylaxis Biology of Blood and Marrow Transplantation. 20: S270-S272. DOI: 10.1016/J.Bbmt.2013.12.455 |
0.472 |
|
| 2014 |
Lazaryan A, Wagner JE, Brunstein CG, Defor T, MacMillan ML, Blazar BR, Weisdorf DJ, Arora M. High-Resolution Donor-Recipient HLA Matching Does Not Influence Acute or Chronic Gvhd in Umbilical Cord Blood Transplantation Biology of Blood and Marrow Transplantation. 20. DOI: 10.1016/J.Bbmt.2013.12.216 |
0.35 |
|
| 2014 |
Watkins BK, Poirier N, Mary C, Blancho G, Singh K, Garrett A, Hamby K, Deane T, Blazar BR, Vanhove B, Kean LS. Preventing Primate Gvhd Using a Novel Antagonistic Anti-CD28 Antibody Plus Rapamycin: Downregulation of CD8 Proliferation Predicts Gvhd-Free Survival Biology of Blood and Marrow Transplantation. 20. DOI: 10.1016/J.Bbmt.2013.12.061 |
0.341 |
|
| 2013 |
Bouchlaka MN, Sckisel GD, Chen M, Mirsoian A, Zamora AE, Maverakis E, Wilkins DE, Alderson KL, Hsiao HH, Weiss JM, Monjazeb AM, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, et al. Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy. The Journal of Experimental Medicine. 210: 2223-37. PMID 24081947 DOI: 10.1084/Jem.20131219 |
0.324 |
|
| 2013 |
Glass TJ, Hui SK, Blazar BR, Lund TC. Effect of radiation dose-rate on hematopoietic cell engraftment in adult zebrafish. Plos One. 8: e73745. PMID 24058487 DOI: 10.1371/Journal.Pone.0073745 |
0.736 |
|
| 2013 |
Saha A, Aoyama K, Taylor PA, Koehn BH, Veenstra RG, Panoskaltsis-Mortari A, Munn DH, Murphy WJ, Azuma M, Yagita H, Fife BT, Sayegh MH, Najafian N, Socie G, Ahmed R, ... ... Blazar BR, et al. Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality. Blood. 122: 3062-73. PMID 24030385 DOI: 10.1182/Blood-2013-05-500801 |
0.786 |
|
| 2013 |
Webber BR, Iacovino M, Choi SH, Tolar J, Kyba M, Blazar BR. DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo. Blood. 122: 2978-86. PMID 24030384 DOI: 10.1182/Blood-2013-03-489369 |
0.672 |
|
| 2013 |
Haarberg KM, Li J, Heinrichs J, Wang D, Liu C, Bronk CC, Kaosaard K, Owyang AM, Holland S, Masuda E, Tso K, Blazar BR, Anasetti C, Beg AA, Yu XZ. Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice. Blood. 122: 2500-11. PMID 23908466 DOI: 10.1182/Blood-2012-12-471938 |
0.564 |
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| 2013 |
Cutler C, Kim HT, Bindra B, Sarantopoulos S, Ho VT, Chen YB, Rosenblatt J, McDonough S, Watanaboonyongcharoen P, Armand P, Koreth J, Glotzbecker B, Alyea E, Blazar BR, Soiffer RJ, et al. Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial. Blood. 122: 1510-7. PMID 23861248 DOI: 10.1182/Blood-2013-04-495895 |
0.435 |
|
| 2013 |
Aoyama K, Saha A, Tolar J, Riddle MJ, Veenstra RG, Taylor PA, Blomhoff R, Panoskaltsis-Mortari A, Klebanoff CA, Socié G, Munn DH, Murphy WJ, Serody JS, Fulton LM, Teshima T, ... ... Blazar BR, et al. Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration. Blood. 122: 2125-34. PMID 23814022 DOI: 10.1182/Blood-2012-11-470252 |
0.86 |
|
| 2013 |
Brunstein CG, Blazar BR, Miller JS, Cao Q, Hippen KL, McKenna DH, Curtsinger J, McGlave PB, Wagner JE. Adoptive transfer of umbilical cord blood-derived regulatory T cells and early viral reactivation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 1271-3. PMID 23806771 DOI: 10.1016/J.Bbmt.2013.06.004 |
0.329 |
|
| 2013 |
Coghill JM, Fowler KA, West ML, Fulton LM, van Deventer H, McKinnon KP, Vincent BG, Lin K, Panoskaltsis-Mortari A, Cook DN, Blazar BR, Serody JS. CC chemokine receptor 8 potentiates donor Treg survival and is critical for the prevention of murine graft-versus-host disease. Blood. 122: 825-36. PMID 23798714 DOI: 10.1182/Blood-2012-06-435735 |
0.518 |
|
| 2013 |
Dietz WM, Skinner NE, Hamilton SE, Jund MD, Heitfeld SM, Litterman AJ, Hwu P, Chen ZY, Salazar AM, Ohlfest JR, Blazar BR, Pennell CA, Osborn MJ. Minicircle DNA is superior to plasmid DNA in eliciting antigen-specific CD8+ T-cell responses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1526-35. PMID 23689601 DOI: 10.1038/Mt.2013.85 |
0.647 |
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| 2013 |
Sharma MD, Huang L, Choi JH, Lee EJ, Wilson JM, Lemos H, Pan F, Blazar BR, Pardoll DM, Mellor AL, Shi H, Munn DH. An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos. Immunity. 38: 998-1012. PMID 23684987 DOI: 10.1016/J.Immuni.2013.01.013 |
0.5 |
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| 2013 |
Matsuoka K, Koreth J, Kim HT, Bascug G, McDonough S, Kawano Y, Murase K, Cutler C, Ho VT, Alyea EP, Armand P, Blazar BR, Antin JH, Soiffer RJ, Ritz J. Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease. Science Translational Medicine. 5: 179ra43. PMID 23552371 DOI: 10.1126/Scitranslmed.3005265 |
0.491 |
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| 2013 |
Osborn MJ, Starker CG, McElroy AN, Webber BR, Riddle MJ, Xia L, DeFeo AP, Gabriel R, Schmidt M, von Kalle C, Carlson DF, Maeder ML, Joung JK, Wagner JE, Voytas DF, ... Blazar BR, et al. TALEN-based gene correction for epidermolysis bullosa. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1151-9. PMID 23546300 DOI: 10.1038/Mt.2013.56 |
0.769 |
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| 2013 |
Lund TC, Kobs AJ, Kramer A, Nyquist M, Kuroki MT, Osborn J, Lidke DS, Low-Nam ST, Blazar BR, Tolar J. Bone marrow stromal and vascular smooth muscle cells have chemosensory capacity via bitter taste receptor expression. Plos One. 8: e58945. PMID 23520545 DOI: 10.1371/Journal.Pone.0058945 |
0.343 |
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| 2013 |
Romee R, Weisdorf DJ, Brunstein C, Wagner JE, Cao Q, Blazar BR, Majhail NS, Vercellotti GM, Miller JS, Arora M. Impact of ABO-mismatch on risk of GVHD after umbilical cord blood transplantation. Bone Marrow Transplantation. 48: 1046-9. PMID 23419434 DOI: 10.1038/Bmt.2013.8 |
0.399 |
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| 2013 |
Nikiforow S, Kim HT, Bindra B, McDonough S, Glotzbecker B, Armand P, Koreth J, Ho VT, Alyea EP, Blazar BR, Ritz J, Soiffer RJ, Antin JH, Cutler CS. Phase I study of alemtuzumab for therapy of steroid-refractory chronic graft-versus-host disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 804-11. PMID 23416855 DOI: 10.1016/J.Bbmt.2013.02.009 |
0.364 |
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| 2013 |
Ahn YO, Blazar BR, Miller JS, Verneris MR. Lineage relationships of human interleukin-22-producing CD56+ RORγt+ innate lymphoid cells and conventional natural killer cells. Blood. 121: 2234-43. PMID 23327921 DOI: 10.1182/Blood-2012-07-440099 |
0.454 |
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| 2013 |
Karras NA, Weeres M, Sessions W, Xu X, Defor T, Young JA, Stefanski H, Brunstein C, Cooley S, Miller JS, Blazar BR, Wagner JE, Verneris MR. A randomized trial of one versus two doses of influenza vaccine after allogeneic transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 109-16. PMID 22940056 DOI: 10.1016/J.Bbmt.2012.08.015 |
0.303 |
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| 2013 |
Tolar J, Xia L, Lees CJ, Riddle M, McElroy A, Keene DR, Lund TC, Osborn MJ, Marinkovich MP, Blazar BR, Wagner JE. Keratinocytes from induced pluripotent stem cells in junctional epidermolysis bullosa. The Journal of Investigative Dermatology. 133: 562-5. PMID 22931927 DOI: 10.1038/Jid.2012.278 |
0.682 |
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| 2013 |
Bachanova V, Cooley S, Defor T, Verneris MR, Zhang B, McKenna D, Curtsinger J, Panoskaltsis-Mortari A, Lewis D, Hippen K, McGlave P, Weisdorf D, Blazar BR, Miller JS. Transient regulatory T-cell (Treg) depletion with IL-2 diphtheria toxin fusion protein enhances clearance of acute myeloid leukemia by haploidentical natural killer (NK) cells Journal For Immunotherapy of Cancer. 1: 1-1. DOI: 10.1186/2051-1426-1-S1-P1 |
0.465 |
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| 2013 |
Kim HT, Bindra B, Alyea EP, Armand P, Cutler CS, Ho VT, Ritz J, Blazar BR, Antin JH, Soiffer RJ, Koreth J. A Phase II Study Of Proteasome-Inhibition For Initial Therapy Of Chronic Graft-Versus-Host Disease Blood. 122: 909-909. DOI: 10.1182/Blood.V122.21.909.909 |
0.35 |
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| 2013 |
Singh K, Stempora L, Kirk AD, Larsen CP, Blazar BR, Kean LS. Rapamycin Rescues The Rapid Disappearance and Loss Of Phenotypic Integrity Of Autologous, Ex-Vivo Expanded Rhesus Macaque Natural Regulatory T Cells After Adoptive Transfer Blood. 122: 895-895. DOI: 10.1182/Blood.V122.21.895.895 |
0.447 |
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| 2013 |
Felices M, Lenvik T, Ankarlo D, Foley B, Curtsinger J, Blazar BR, Anderson SK, Miller JS. Functional NK Cell Repertoires Are Determined By Survival Mechanisms Through IL-2Ra and FasL Blood. 122: 786-786. DOI: 10.1182/Blood.V122.21.786.786 |
0.429 |
|
| 2013 |
Verneris MR, Ahn Y, Weeres MA, Blazar BR, Miller JS. Death Receptor 3 (DR3) Is Expressed By Innate Lymphoid Cells (ILC) and Ligation By Tumor Like Antigen-1 (TL1A) Leads To Costimulation and Significant ILC Expansion Blood. 122: 782-782. DOI: 10.1182/Blood.V122.21.782.782 |
0.373 |
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| 2013 |
Cooley S, Curtsinger J, Shanley R, Brunstein C, Blazar BR, Wagner JE, Miller JS, Verneris MR. Early NK Cell Proliferation After Umbilical Cord Blood Transplantation Is Associated With Superior Disease-Free Survival Due To Reduced Leukemia Relapse Blood. 122: 4610-4610. DOI: 10.1182/Blood.V122.21.4610.4610 |
0.475 |
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| 2013 |
Bommiasamy H, Ott L, West S, Fulton LM, Panoskaltsis-Mortari A, Blazar BR, Fouser L, Serody J. IL-22 Is Critical To The Pathogenesis Of Cutaneous Gvhd Mediated By Th17 Cells Blood. 122: 4482-4482. DOI: 10.1182/Blood.V122.21.4482.4482 |
0.515 |
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| 2013 |
Pai C, Mirsoian A, Grossenbacher S, Ames E, Sun K, Chen M, Blazar BR, Abedi M, Murphy WJ. Organ-Specific Protection By Bortezomib On The Treatment Of Cutaneous Chronic and Acute GvHD Blood. 122: 4473-4473. DOI: 10.1182/Blood.V122.21.4473.4473 |
0.472 |
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| 2013 |
Koreth J, Kim HT, Lange PB, Bindra B, Armand P, Cutler CS, Ho VT, Glotzbecker B, Ritz J, Blazar BR, Soiffer RJ, Antin JH, Alyea EP. A Bortezomib-Based Regimen Offers Excellent Outcomes In Myeloablative HLA-Mismatched and Unrelated Donor Transplantation: Phase II Results Blood. 122: 3335-3335. DOI: 10.1182/Blood.V122.21.3335.3335 |
0.398 |
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| 2013 |
Flynn R, Du J, Veenstra R, Panoskaltsis-Mortari A, Price A, Taylor PA, Freeman GJ, Browning JL, Serody J, Murphy WJ, Munn D, Sarantopoulos S, Luznik L, Maillard I, Koreth J, ... ... Blazar BR, et al. Germinal Center Generation and Maintenance By T Follicular Helper Cells Is Required For The Development Of Chronic Gvhd Associated Bronchiolitis Obliterans In a Preclinical Model Blood. 122: 292-292. DOI: 10.1182/Blood.V122.21.292.292 |
0.869 |
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