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Kevin M. Dean, Ph.D. - Publications

Affiliations: 
2002-2006 Chemistry Willamette University, Salem, OR, United States 
 2007-2014 Chemistry and Biochemistry University of Colorado, Boulder, Boulder, CO, United States 
 2014- Cell Biology and Bioinformatics University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Biochemistry, General Biophysics
Website:
www.kevinmdean.com
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59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mcfadden C, Marin Z, Chen B, Daetwyler S, Wang X, Rajendran D, Dean KM, Fiolka R. Adaptive optics in an oblique plane microscope. Biomedical Optics Express. 15: 4498-4512. PMID 39346993 DOI: 10.1364/BOE.524013  0.725
2024 Lin J, Mehra D, Marin Z, Wang X, Borges HM, Shen Q, Gałecki S, Haug J, Abbott DH, Dean KM. Mechanically sheared axially swept light-sheet microscopy. Biomedical Optics Express. 15: 5314-5327. PMID 39296406 DOI: 10.1364/BOE.526145  0.318
2024 Marin Z, Wang X, Collison DW, McFadden C, Lin J, Borges HM, Chen B, Mehra D, Shen Q, Gałecki S, Daetwyler S, Sheppard SJ, Thien P, Porter BA, Conzen SD, ... ... Dean KM, et al. Navigate: an open-source platform for smart light-sheet microscopy. Nature Methods. PMID 39261640 DOI: 10.1038/s41592-024-02413-4  0.618
2024 Ju RJ, Falconer AD, Schmidt CJ, Enriquez Martinez MA, Dean KM, Fiolka RP, Sester DP, Nobis M, Timpson P, Lomakin AJ, Danuser G, White MD, Haass NK, Oelz DB, Stehbens SJ. Compression-dependent microtubule reinforcement enables cells to navigate confined environments. Nature Cell Biology. PMID 39160291 DOI: 10.1038/s41556-024-01476-x  0.706
2024 Nanes BA, Bhatt K, Azarova E, Rajendran D, Munawar S, Isogai T, Dean KM, Danuser G. Shifts in keratin isoform expression activate motility signals during wound healing. Developmental Cell. PMID 39002537 DOI: 10.1016/j.devcel.2024.06.011  0.478
2024 Driscoll MK, Welf ES, Weems A, Sapoznik E, Zhou F, Murali VS, García-Arcos JM, Roh-Johnson M, Piel M, Dean KM, Fiolka R, Danuser G. Proteolysis-free amoeboid migration of melanoma cells through crowded environments via bleb-driven worrying. Developmental Cell. PMID 38870943 DOI: 10.1016/j.devcel.2024.05.024  0.708
2024 Zhou FY, Yapp C, Shang Z, Daetwyler S, Marin Z, Islam MT, Nanes BA, Jenkins E, Gihana GM, Chang BJ, Weems A, Dustin M, Morrison SJ, Fiolka RP, Dean KM, et al. A general algorithm for consensus 3D cell segmentation from 2D segmented stacks. Biorxiv : the Preprint Server For Biology. PMID 38766074 DOI: 10.1101/2024.05.03.592249  0.7
2024 Lin J, Mehra D, Marin Z, Wang X, Borges HM, Shen Q, Gałecki S, Haug J, Dean KM. Mechanically Sheared Axially Swept Light-Sheet Microscopy. Biorxiv : the Preprint Server For Biology. PMID 38645073 DOI: 10.1101/2024.04.10.588892  0.314
2024 McFadden C, Marin Z, Chen B, Daetwyler S, Xiaoding W, Rajendran D, Dean KM, Fiolka R. Adaptive Optics in an Oblique Plane Microscope. Biorxiv : the Preprint Server For Biology. PMID 38562744 DOI: 10.1101/2024.03.21.586191  0.725
2024 Marin Z, Wang X, Collison DW, McFadden C, Lin J, Borges H, Chen B, Mehra D, Shen Q, Galecki S, Daetwyler S, Fiolka R, Dean KM. navigate: an open-source platform for smart light-sheet microscopy. Biorxiv : the Preprint Server For Biology. PMID 38370811 DOI: 10.1101/2024.02.09.579083  0.666
2023 Roudot P, Legant WR, Zou Q, Dean KM, Isogai T, Welf ES, David AF, Gerlich DW, Fiolka R, Betzig E, Danuser G. u-track3D: Measuring, navigating, and validating dense particle trajectories in three dimensions. Cell Reports Methods. 100655. PMID 38042149 DOI: 10.1016/j.crmeth.2023.100655  0.683
2023 Nanes BA, Bhatt K, Azarova E, Rajendran D, Isogai T, Dean KM, Danuser G. Keratin isoform shifts modulate motility signals during wound healing. Biorxiv : the Preprint Server For Biology. PMID 37205459 DOI: 10.1101/2023.05.04.538989  0.465
2023 Weems AD, Welf ES, Driscoll MK, Zhou FY, Mazloom-Farsibaf H, Chang BJ, Murali VS, Gihana GM, Weiss BG, Chi J, Rajendran D, Dean KM, Fiolka R, Danuser G. Blebs promote cell survival by assembling oncogenic signalling hubs. Nature. PMID 36859545 DOI: 10.1038/s41586-023-05758-6  0.711
2022 Chen B, Chang BJ, Zhou FY, Daetwyler S, Sapoznik E, Nanes BA, Terrazas I, Gihana GM, Castro LP, Chan IS, Conacci-Sorrell M, Dean KM, Millett-Sikking A, York AG, Fiolka R. Increasing the field-of-view in oblique plane microscopy via optical tiling. Biomedical Optics Express. 13: 5616-5627. PMID 36733723 DOI: 10.1364/BOE.467969  0.688
2022 Chen B, Chang BJ, Roudot P, Zhou F, Sapoznik E, Marlar-Pavey M, Hayes JB, Brown PT, Zeng CW, Lambert T, Friedman JR, Zhang CL, Burnette DT, Shepherd DP, Dean KM, et al. Resolution doubling in light-sheet microscopy via oblique plane structured illumination. Nature Methods. PMID 36280718 DOI: 10.1038/s41592-022-01635-8  0.726
2022 Dean KM, Chakraborty T, Daetwyler S, Lin J, Garrelts G, M'Saad O, Mekbib HT, Voigt FF, Schaettin M, Stoeckli ET, Helmchen F, Bewersdorf J, Fiolka R. Isotropic imaging across spatial scales with axially swept light-sheet microscopy. Nature Protocols. PMID 35831614 DOI: 10.1038/s41596-022-00706-6  0.712
2021 Liu H, Hiremath C, Patterson Q, Vora S, Shang Z, Jamieson A, Fiolka R, Dean K, Dellinger M, Marciano D. Heterozygous Mutation of Reduces Renal Lymphatics Without Renal Dysfunction. Journal of the American Society of Nephrology : Jasn. PMID 34551997 DOI: 10.1681/ASN.2021010061  0.566
2021 Chang BJ, Manton JD, Sapoznik E, Pohlkamp T, Terrones TS, Welf ES, Murali VS, Roudot P, Hake K, Whitehead L, York AG, Dean KM, Fiolka R. Real-time multi-angle projection imaging of biological dynamics. Nature Methods. PMID 34183831 DOI: 10.1038/s41592-021-01175-7  0.677
2021 Han SJ, Azarova EV, Whitewood AJ, Bachir A, Guttierrez E, Groisman A, Horwitz AR, Goult BT, Dean KM, Danuser G. Pre-complexation of talin and vinculin without tension is required for efficient nascent adhesion maturation. Elife. 10. PMID 33783351 DOI: 10.7554/eLife.66151  0.452
2020 Welf ES, Miles CE, Huh J, Sapoznik E, Chi J, Driscoll MK, Isogai T, Noh J, Weems AD, Pohlkamp T, Dean K, Fiolka R, Mogilner A, Danuser G. Actin-Membrane Release Initiates Cell Protrusions. Developmental Cell. PMID 33308479 DOI: 10.1016/j.devcel.2020.11.024  0.687
2020 Sapoznik E, Chang BJ, Huh J, Ju RJ, Azarova EV, Pohlkamp T, Welf ES, Broadbent D, Carisey AF, Stehbens SJ, Lee KM, Marin A, Hanker AB, Schmidt JC, Arteaga CL, ... ... Dean KM, et al. A versatile Oblique Plane Microscope for large-scale and high-resolution imaging of subcellular dynamics. Elife. 9. PMID 33179596 DOI: 10.7554/eLife.57681  0.69
2020 Lee KM, Guerrero-Zotano AL, Servetto A, Sudhan DR, Lin CC, Formisano L, Jansen VM, González-Ericsson P, Sanders ME, Stricker TP, Raj G, Dean KM, Fiolka R, Cantley LC, Hanker AB, et al. Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer. Nature Communications. 11: 5488. PMID 33127913 DOI: 10.1038/s41467-020-19291-x  0.554
2020 Chakraborty T, Chen B, Daetwyler S, Chang BJ, Vanderpoorten O, Sapoznik E, Kaminski CF, Knowles TPJ, Dean KM, Fiolka R. Converting lateral scanning into axial focusing to speed up three-dimensional microscopy. Light, Science & Applications. 9: 165. PMID 33024553 DOI: 10.1038/s41377-020-00401-9  0.688
2020 Chen B, Chakraborty T, Daetwyler S, Manton JD, Dean K, Fiolka R. Extended depth of focus multiphoton microscopy via incoherent pulse splitting. Biomedical Optics Express. 11: 3830-3842. PMID 33014569 DOI: 10.1364/Boe.393931  0.719
2020 Chang BJ, Dean KM, Fiolka R. Systematic and quantitative comparison of lattice and Gaussian light-sheets. Optics Express. 28: 27052-27077. PMID 32906967 DOI: 10.1364/Oe.400164  0.686
2019 Chakraborty T, Driscoll MK, Jeffery E, Murphy MM, Roudot P, Chang BJ, Vora S, Wong WM, Nielson CD, Zhang H, Zhemkov V, Hiremath C, De La Cruz ED, Yi Y, Bezprozvanny I, ... ... Dean KM, et al. Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution. Nature Methods. 16: 1109-1113. PMID 31673159 DOI: 10.1038/S41592-019-0615-4  0.763
2019 Driscoll MK, Welf ES, Jamieson AR, Dean KM, Isogai T, Fiolka R, Danuser G. Robust and automated detection of subcellular morphological motifs in 3D microscopy images. Nature Methods. PMID 31501548 DOI: 10.1038/S41592-019-0539-Z  0.746
2019 Mohan AS, Dean KM, Isogai T, Kasitinon SY, Murali VS, Roudot P, Groisman A, Reed DK, Welf ES, Han SJ, Noh J, Danuser G. Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1 Melanoma Cells. Developmental Cell. 49: 444-460.e9. PMID 31063759 DOI: 10.1016/J.Devcel.2019.04.007  0.547
2019 Chang BJ, Kittisopikul M, Dean KM, Roudot P, Welf ES, Fiolka R. Universal light-sheet generation with field synthesis. Nature Methods. PMID 30804550 DOI: 10.1038/S41592-019-0327-9  0.667
2018 Mohan A, Dean K, Murali V, Yuan S, Isogai T, Han S, Welf E, Danuser G. 1264 Rac1P29S coordinates the actin cytoskeleton to mediate a mechanosensitive proliferative advantage in melanoma Journal of Investigative Dermatology. 138: S214. DOI: 10.1016/J.Jid.2018.03.1279  0.499
2018 Fiolka RP, Dean KM, Driscoll M, Welf E, Danuser G. Quantitative Imaging of Cellular Morphodynamics and Signaling with Light-Sheet Microscopy Biophysical Journal. 114: 6a-7a. DOI: 10.1016/J.Bpj.2017.11.068  0.756
2017 Dean KM, Roudot P, Welf ES, Pohlkamp T, Garrelts G, Herz J, Fiolka R. Imaging Subcellular Dynamics with Fast and Light-Efficient Volumetrically Parallelized Microscopy. Optica. 4: 263-271. PMID 28944279 DOI: 10.1364/OPTICA.4.000263  0.721
2017 Dean KM, Fiolka R. Lossless Three-Dimensional Parallelization in Digitally Scanned Light-Sheet Fluorescence Microscopy. Scientific Reports. 7: 9332. PMID 28839150 DOI: 10.1038/S41598-017-08113-8  0.746
2017 Mohan A, Dean K, Han S, Welf E, Danuser G. LB993 Focal adhesions mediate Rac1P29S-dependent drug resistance to MAPK inhibitors in melanoma Journal of Investigative Dermatology. 137: B11. DOI: 10.1016/J.Jid.2017.07.075  0.476
2016 Chu J, Oh Y, Sens A, Ataie N, Dana H, Macklin JJ, Laviv T, Welf ES, Dean KM, Zhang F, Kim BB, Tang CT, Hu M, Baird MA, Davidson MW, et al. A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo. Nature Biotechnology. PMID 27240196 DOI: 10.1038/Nbt.3550  0.738
2016 Williamson JC, Brown AM, Helvie EN, Dean KM. Determination of liquid-liquid critical point composition using 90^{∘} laser light scattering. Physical Review. E. 93: 042610. PMID 27176355 DOI: 10.1103/Physreve.93.042610  0.409
2016 Dean KM, Roudot P, Reis CR, Welf ES, Mettlen M, Fiolka R. Diagonally Scanned Light-Sheet Microscopy for Fast Volumetric Imaging of Adherent Cells. Biophysical Journal. 110: 1456-65. PMID 27028654 DOI: 10.1016/J.Bpj.2016.01.029  0.739
2016 Welf ES, Driscoll MK, Dean KM, Schäfer C, Chu J, Davidson MW, Lin MZ, Danuser G, Fiolka R. Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments. Developmental Cell. 36: 462-75. PMID 26906741 DOI: 10.1016/J.Devcel.2016.01.022  0.757
2016 Dean KM, Driscoll MK, Welf ES, Fiolka R. Microscope technologies for quantitative imaging in 3D microenvironments Spie Newsroom. DOI: 10.1117/2.1201608.006670  0.659
2015 Dean KM, Roudot P, Welf ES, Danuser G, Fiolka R. Deconvolution-free Subcellular Imaging with Axially Swept Light Sheet Microscopy. Biophysical Journal. 108: 2807-15. PMID 26083920 DOI: 10.1016/J.Bpj.2015.05.013  0.797
2015 Dean KM, Davis LM, Lubbeck JL, Manna P, Friis P, Palmer AE, Jimenez R. High-speed multiparameter photophysical analyses of fluorophore libraries. Analytical Chemistry. 87: 5026-30. PMID 25898152 DOI: 10.1021/Acs.Analchem.5B00607  0.802
2015 Dean KM, Lubbeck JL, Davis LM, Regmi CK, Chapagain PP, Gerstman BS, Jimenez R, Palmer AE. Microfluidics-based selection of red-fluorescent proteins with decreased rates of photobleaching. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 263-73. PMID 25477249 DOI: 10.1039/C4Ib00251B  0.816
2015 Dean KM, Roudot P, Welf ES, Danuser G, Fiolka R. Deconvolution-free Subcellular Imaging with Axially Swept Light Sheet Microscopy Biophysical Journal. 108: 2807-2815. DOI: 10.1016/j.bpj.2015.05.013  0.742
2014 Dean KM, Fiolka R. Uniform and scalable light-sheets generated by extended focusing. Optics Express. 22: 26141-52. PMID 25401646 DOI: 10.1364/OE.22.026141  0.703
2014 Dean KM, Palmer AE. Advances in fluorescence labeling strategies for dynamic cellular imaging. Nature Chemical Biology. 10: 512-23. PMID 24937069 DOI: 10.1038/Nchembio.1556  0.699
2014 Dean KM, Davis LM, Lubbeck JL, Manna P, Palmer AE, Jimenez R. Microfluidic flow cytometer for multiparameter screening of fluorophore photophysics Conference On Lasers and Electro-Optics Europe - Technical Digest. 2014.  0.799
2013 Qin Y, Miranda JG, Stoddard CI, Dean KM, Galati DF, Palmer AE. Direct comparison of a genetically encoded sensor and small molecule indicator: implications for quantification of cytosolic Zn(2+). Acs Chemical Biology. 8: 2366-71. PMID 23992616 DOI: 10.1021/Cb4003859  0.656
2013 Davis LM, Lubbeck JL, Dean KM, Palmer AE, Jimenez R. Microfluidic cell sorter for use in developing red fluorescent proteins with improved photostability. Lab On a Chip. 13: 2320-7. PMID 23636097 DOI: 10.1039/C3Lc50191D  0.822
2012 Dean KM, Qin Y, Palmer AE. Visualizing metal ions in cells: an overview of analytical techniques, approaches, and probes. Biochimica Et Biophysica Acta. 1823: 1406-15. PMID 22521452 DOI: 10.1016/J.Bbamcr.2012.04.001  0.655
2012 Lubbeck JL, Dean KM, Ma H, Palmer AE, Jimenez R. Microfluidic flow cytometer for quantifying photobleaching of fluorescent proteins in cells. Analytical Chemistry. 84: 3929-37. PMID 22424298 DOI: 10.1021/Ac202825Z  0.812
2012 Davis LM, Lubbeck JL, Dean KM, Palmer AE, Jimenez R. Real-time analysis of multi-laser-beam fluorescence for timed control of laser tweezers in a microfluidic cell-sorting device Proceedings of Spie - the International Society For Optical Engineering. 8412. DOI: 10.1117/12.2001362  0.817
2012 Ma H, Gibson EA, Dittmer PJ, Dean K, Palmer AE, Jimenez R. Heterogeneity and Kinetics of FRET-Based Ca2+ and Zn2+ Sensors in HeLa Cells Biophysical Journal. 102: 209a. DOI: 10.1016/J.Bpj.2011.11.1139  0.77
2012 Lubbeck JL, Dean KM, Davis LM, Palmer AE, Jimenez R. Microfluidic Cytometer For Simultaneous High-Throughput Screening of Fluorescent Proteins on the Basis of Fluorescence Lifetime, Photostability, and Brightness Biophysical Journal. 102: 208a-209a. DOI: 10.1016/J.Bpj.2011.11.1138  0.818
2011 Dean KM, Lubbeck JL, Binder JK, Schwall LR, Jimenez R, Palmer AE. Analysis of red-fluorescent proteins provides insight into dark-state conversion and photodegradation. Biophysical Journal. 101: 961-9. PMID 21843488 DOI: 10.1016/J.Bpj.2011.06.055  0.782
2011 Dean KM, Williamson JC. The stir-settle approach to semiautomated light scattering determination of liquid-liquid coexistence curves Journal of Chemical and Engineering Data. 56: 1433-1437. DOI: 10.1021/Je101143G  0.417
2011 Lubbeck JL, Dean KM, Davis LM, Palmer AE, Jimenez R. A Microfluidic Cell Sorter for Directed Evolution of Fluorescent Proteins Based on Dark-State Conversion and Photobleaching Biophysical Journal. 100: 175a. DOI: 10.1016/J.Bpj.2010.12.1176  0.824
2010 Dean KM, Babayco CB, Sluss DR, Williamson JC. The accuracy of liquid-liquid phase transition temperatures determined from semiautomated light scattering measurements. The Journal of Chemical Physics. 133: 074506. PMID 20726651 DOI: 10.1063/1.3469778  0.416
2010 Lubbeck JL, Dean KM, Jiminez R, Palmer AE. A Microfluidic Cytometer for High-Throughput and Quantitative Single Cell Red Fluorescent Protein Photobleaching Biophysical Journal. 98: 584a. DOI: 10.1016/J.Bpj.2009.12.3173  0.827
2009 Gibson EA, Dittmer PJ, Dean K, Jimenez R, Palmer AE. A Microfluidic Platform For High-Throughput Screening And Sorting Of Cells Based Upon FRET Response Biophysical Journal. 96: 544a-545a. DOI: 10.1016/J.Bpj.2008.12.2948  0.816
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