Mark A. Lovell - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Biochemistry, Analytical Chemistry

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Ellison EM, Bradley-Whitman MA, Lovell MA. Single-Base Resolution Mapping of 5-Hydroxymethylcytosine Modifications in Hippocampus of Alzheimer's Disease Subjects. Journal of Molecular Neuroscience : Mn. PMID 28866733 DOI: 10.1007/S12031-017-0969-Y  0.387
2017 Sompol P, Furman JL, Pleiss MM, Kraner SD, Artiushin IA, Batten SR, Quintero JE, Simmerman LA, Beckett TL, Lovell MA, Murphy MP, Gerhardt GA, Norris CM. Calcineurin/NFAT signaling in activated astrocytes drives network hyperexcitability in Aβ-bearing mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28559377 DOI: 10.1523/Jneurosci.0877-17.2017  0.349
2017 Kryscio RJ, Abner EL, Caban-Holt A, Lovell M, Goodman P, Darke AK, Yee M, Crowley J, Schmitt FA. Association of Antioxidant Supplement Use and Dementia in the Prevention of Alzheimer's Disease by Vitamin E and Selenium Trial (PREADViSE). Jama Neurology. PMID 28319243 DOI: 10.1001/Jamaneurol.2016.5778  0.316
2016 Ellison EM, Abner EL, Lovell MA. Multiregional analysis of global 5-methylcytosine and 5-hydroxymethylcytosine throughout the progression of Alzheimer's disease. Journal of Neurochemistry. PMID 27889911 DOI: 10.1111/Jnc.13912  0.404
2016 Lovell MA, Lynn BC, Fister S, Bradley-Whitman M, Murphy MP, Beckett TL, Norris CM. A Novel Small Molecule Modulator of Amyloid Pathology. Journal of Alzheimer's Disease : Jad. PMID 27163808 DOI: 10.3233/Jad-151160  0.344
2015 Bradley-Whitman MA, Abner E, Lynn BC, Lovell MA. A Novel Plasma Based Biomarker of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 47: 761-71. PMID 26401710 DOI: 10.3233/Jad-150183  0.363
2015 Lovell MA, Abner E, Kryscio R, Xu L, Fister SX, Lynn BC. Calcium Channel Blockers, Progression to Dementia, and Effects on Amyloid Beta Peptide Production. Oxidative Medicine and Cellular Longevity. 2015: 787805. PMID 26221415 DOI: 10.1155/2015/787805  0.35
2015 Bradley-Whitman MA, Lovell MA. Biomarkers of lipid peroxidation in Alzheimer disease (AD): an update. Archives of Toxicology. 89: 1035-44. PMID 25895140 DOI: 10.1007/S00204-015-1517-6  0.41
2014 Bradley-Whitman MA, Timmons MD, Beckett TL, Murphy MP, Lynn BC, Lovell MA. Nucleic acid oxidation: an early feature of Alzheimer's disease. Journal of Neurochemistry. 128: 294-304. PMID 24032632 DOI: 10.1111/Jnc.12444  0.423
2013 Bradley-Whitman MA, Lovell MA. Epigenetic changes in the progression of Alzheimer's disease Mechanisms of Ageing and Development. 134: 486-495. PMID 24012631 DOI: 10.1016/J.Mad.2013.08.005  0.427
2012 Lovell MA, Bradley MA, Fister SX. 4-Hydroxyhexenal (HHE) impairs glutamate transport in astrocyte cultures. Journal of Alzheimer's Disease : Jad. 32: 139-46. PMID 22766736 DOI: 10.3233/Jad-2012-120409  0.677
2012 Lyubartseva G, Lovell MA. A potential role for zinc alterations in the pathogenesis of Alzheimer's disease. Biofactors (Oxford, England). 38: 98-106. PMID 22447723 DOI: 10.1002/Biof.199  0.765
2012 Bradley MA, Xiong-Fister S, Markesbery WR, Lovell MA. Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression. Neurobiology of Aging. 33: 1034-44. PMID 20965613 DOI: 10.1016/J.Neurobiolaging.2010.08.016  0.708
2011 Weidner AM, Bradley MA, Beckett TL, Niedowicz DM, Dowling AL, Matveev SV, LeVine H, Lovell MA, Murphy MP. RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer's disease. Plos One. 6: e24930. PMID 21949792 DOI: 10.1371/Journal.Pone.0024930  0.694
2011 Lovell MA, Soman S, Bradley MA. Oxidatively modified nucleic acids in preclinical Alzheimer's disease (PCAD) brain. Mechanisms of Ageing and Development. 132: 443-8. PMID 21878349 DOI: 10.1016/J.Mad.2011.08.003  0.709
2011 Timmons MD, Bradley MA, Lovell MA, Lynn BC. Procedure for the isolation of mitochondria, cytosolic and nuclear material from a single piece of neurological tissue for high-throughput mass spectral analysis. Journal of Neuroscience Methods. 197: 279-82. PMID 21392528 DOI: 10.1016/J.Jneumeth.2011.02.027  0.633
2010 Bradley MA, Markesbery WR, Lovell MA. Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease. Free Radical Biology & Medicine. 48: 1570-6. PMID 20171275 DOI: 10.1016/J.Freeradbiomed.2010.02.016  0.69
2010 Lynn BC, Wang J, Markesbery WR, Lovell MA. Quantitative changes in the mitochondrial proteome from subjects with mild cognitive impairment, early stage, and late stage Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 19: 325-39. PMID 20061648 DOI: 10.3233/Jad-2010-1254  0.382
2010 Lovell MA. Similarities and differences between mild cognitive impairment and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 19: 219. PMID 20061640 DOI: 10.3233/Jad-2010-1263  0.38
2010 Lyubartseva G, Smith JL, Markesbery WR, Lovell MA. Alterations of zinc transporter proteins ZnT-1, ZnT-4 and ZnT-6 in preclinical Alzheimer's disease brain. Brain Pathology (Zurich, Switzerland). 20: 343-50. PMID 19371353 DOI: 10.1111/J.1750-3639.2009.00283.X  0.779
2010 Smith CD, Chebrolu H, Andersen AH, Powell DA, Lovell MA, Xiong S, Gold BT. White matter diffusion alterations in normal women at risk of Alzheimer's disease. Neurobiology of Aging. 31: 1122-31. PMID 18801597 DOI: 10.1016/J.Neurobiolaging.2008.08.006  0.329
2010 Lovell MA. Upcoming Meetings Related to Alzheimer's Disease* Journal of Alzheimer's Disease. 19: 373-374. DOI: 10.3233/Jad-2010-1264  0.333
2009 Lovell MA, Xiong S, Lyubartseva G, Markesbery WR. Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice. Free Radical Biology & Medicine. 46: 1527-33. PMID 19303433 DOI: 10.1016/J.Freeradbiomed.2009.03.008  0.748
2009 Lovell MA. A potential role for alterations of zinc and zinc transport proteins in the progression of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 16: 471-83. PMID 19276540 DOI: 10.3233/Jad-2009-0992  0.371
2009 Fu YJ, Xiong S, Lovell MA, Lynn BC. Quantitative proteomic analysis of mitochondria in aging PS-1 transgenic mice. Cellular and Molecular Neurobiology. 29: 649-64. PMID 19241155 DOI: 10.1007/S10571-009-9359-5  0.317
2008 Dong J, Robertson JD, Markesbery WR, Lovell MA. Serum zinc in the progression of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 15: 443-50. PMID 18997297 DOI: 10.3233/Jad-2008-15310  0.349
2008 Shao C, Xiong S, Li GM, Gu L, Mao G, Markesbery WR, Lovell MA. Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer's disease brain. Free Radical Biology & Medicine. 45: 813-9. PMID 18598755 DOI: 10.1016/J.Freeradbiomed.2008.06.003  0.394
2008 Sonnen JA, Breitner JC, Lovell MA, Markesbery WR, Quinn JF, Montine TJ. Free radical-mediated damage to brain in Alzheimer's disease and its transgenic mouse models. Free Radical Biology & Medicine. 45: 219-30. PMID 18482592 DOI: 10.1016/J.Freeradbiomed.2008.04.022  0.394
2008 Lovell MA, Lynn BC, Xiong S, Quinn JF, Kaye J, Markesbery WR. An aberrant protein complex in CSF as a biomarker of Alzheimer disease. Neurology. 70: 2212-8. PMID 18448869 DOI: 10.1212/01.Wnl.0000312383.39973.88  0.338
2007 Lovell MA, Markesbery WR. Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease. Nucleic Acids Research. 35: 7497-504. PMID 17947327 DOI: 10.1093/Nar/Gkm821  0.37
2007 Markesbery WR, Lovell MA. Damage to lipids, proteins, DNA, and RNA in mild cognitive impairment. Archives of Neurology. 64: 954-6. PMID 17620484 DOI: 10.1001/Archneur.64.7.954  0.365
2007 Lovell MA, Markesbery WR. Oxidative damage in mild cognitive impairment and early Alzheimer's disease. Journal of Neuroscience Research. 85: 3036-40. PMID 17510979 DOI: 10.1002/Jnr.21346  0.409
2007 Mao G, Pan X, Zhu BB, Zhang Y, Yuan F, Huang J, Lovell MA, Lee MP, Markesbery WR, Li GM, Gu L. Identification and characterization of OGG1 mutations in patients with Alzheimer's disease. Nucleic Acids Research. 35: 2759-66. PMID 17426120 DOI: 10.1093/Nar/Gkm189  0.388
2007 Xiong S, Markesbery WR, Shao C, Lovell MA. Seleno-L-methionine protects against beta-amyloid and iron/hydrogen peroxide-mediated neuron death. Antioxidants & Redox Signaling. 9: 457-67. PMID 17280487 DOI: 10.1089/Ars.2006.1363  0.303
2007 Mehta SG, Watts GD, Adamson JL, Hutton M, Umberger G, Xiong S, Ramdeen S, Lovell MA, Kimonis VE, Smith CD. APOE is a potential modifier gene in an autosomal dominant form of frontotemporal dementia (IBMPFD). Genetics in Medicine : Official Journal of the American College of Medical Genetics. 9: 9-13. PMID 17224685 DOI: 10.1097/Gim.0B013E31802D830D  0.327
2006 Markesbery WR, Lovell MA. DNA oxidation in Alzheimer's disease. Antioxidants & Redox Signaling. 8: 2039-45. PMID 17034348 DOI: 10.1089/Ars.2006.8.2039  0.363
2006 Lovell MA, Markesbery WR. Amyloid beta peptide, 4-hydroxynonenal and apoptosis. Current Alzheimer Research. 3: 359-64. PMID 17017866 DOI: 10.2174/156720506778249506  0.345
2006 Lovell MA, Smith JL, Markesbery WR. Elevated zinc transporter-6 in mild cognitive impairment, Alzheimer disease, and pick disease. Journal of Neuropathology and Experimental Neurology. 65: 489-98. PMID 16772872 DOI: 10.1097/01.Jnen.0000229237.98124.91  0.393
2006 Liu X, Lovell MA, Lynn BC. Detection and quantification of endogenous cyclic DNA adducts derived from trans-4-hydroxy-2-nonenal in human brain tissue by isotope dilution capillary liquid chromatography nanoelectrospray tandem mass spectrometry. Chemical Research in Toxicology. 19: 710-8. PMID 16696574 DOI: 10.1021/Tx0502903  0.305
2006 Smith JL, Xiong S, Markesbery WR, Lovell MA. Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain. Neuroscience. 140: 879-88. PMID 16580781 DOI: 10.1016/J.Neuroscience.2006.02.049  0.377
2006 Wang J, Markesbery WR, Lovell MA. Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment. Journal of Neurochemistry. 96: 825-32. PMID 16405502 DOI: 10.1111/J.1471-4159.2005.03615.X  0.368
2006 Smith JL, Xiong S, Lovell MA. 4-Hydroxynonenal disrupts zinc export in primary rat cortical cells Neurotoxicology. 27: 1-5. PMID 16125244 DOI: 10.1016/J.Neuro.2005.05.009  0.355
2006 Williams TI, Lynn BC, Markesbery WR, Lovell MA. Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease. Neurobiology of Aging. 27: 1094-9. PMID 15993986 DOI: 10.1016/J.Neurobiolaging.2005.06.004  0.408
2006 Lovell MA, Geiger H, Van Zant GE, Lynn BC, Markesbery WR. Isolation of neural precursor cells from Alzheimer's disease and aged control postmortem brain. Neurobiology of Aging. 27: 909-17. PMID 15979211 DOI: 10.1016/J.Neurobiolaging.2005.05.004  0.379
2005 Markesbery WR, Kryscio RJ, Lovell MA, Morrow JD. Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment. Annals of Neurology. 58: 730-5. PMID 16240347 DOI: 10.1002/Ana.20629  0.367
2005 Lovell MA, Smith JL, Xiong S, Markesbery WR. Alterations in zinc transporter protein-1 (ZnT-1) in the brain of subjects with mild cognitive impairment, early, and late-stage Alzheimer's disease. Neurotoxicity Research. 7: 265-71. PMID 16179263 DOI: 10.1007/Bf03033884  0.425
2005 Lovell MA, Markesbery WR. Ectopic expression of Musashi-1 in Alzheimer disease and Pick disease. Journal of Neuropathology and Experimental Neurology. 64: 675-80. PMID 16106215 DOI: 10.1097/01.Jnen.0000173891.17176.5B  0.377
2005 Smith CD, Kryscio RJ, Schmitt FA, Lovell MA, Blonder LX, Rayens WS, Andersen AH. Longitudinal functional alterations in asymptomatic women at risk for Alzheimer's disease Journal of Neuroimaging. 15: 271-277. PMID 15951411 DOI: 10.1111/J.1552-6569.2005.Tb00321.X  0.339
2005 Williams TI, Lovell MA, Lynn BC. Analysis of derivatized biogenic aldehydes by LC tandem mass spectrometry. Analytical Chemistry. 77: 3383-9. PMID 15889933 DOI: 10.1021/Ac048265+  0.322
2005 Wang J, Xiong S, Xie C, Markesbery WR, Lovell MA. Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease. Journal of Neurochemistry. 93: 953-62. PMID 15857398 DOI: 10.1111/J.1471-4159.2005.03053.X  0.387
2005 Lovell MA, Xiong S, Markesbery WR, Lynn BC. Quantitative proteomic analysis of mitochondria from primary neuron cultures treated with amyloid beta peptide. Neurochemical Research. 30: 113-22. PMID 15756939 DOI: 10.1007/S11064-004-9692-5  0.331
2004 Lovell MA, Lynn BC, Markesbery WR. O2-04-05 Proteomic analysis of mitochondria from control, early, and late state Alzheimer's disease subjects Neurobiology of Aging. 25: S39-S40. DOI: 10.1016/S0197-4580(04)80131-3  0.326
2003 Lovell MA, Xie C, Xiong S, Markesbery WR. Wilms' tumor suppressor (WT1) is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer's disease. Brain Research. 983: 84-96. PMID 12914969 DOI: 10.1016/S0006-8993(03)03032-4  0.355
2003 Lovell MA, Xie C, Xiong S, Markesbery WR. Protection against amyloid beta peptide and iron/hydrogen peroxide toxicity by alpha lipoic acid. Journal of Alzheimer's Disease : Jad. 5: 229-39. PMID 12897407 DOI: 10.3233/Jad-2003-5306  0.311
2002 Lovell MA, Robertson JD, Buchholz BA, Xie C, Markesbery WR. Use of bomb pulse carbon-14 to age senile plaques and neurofibrillary tangles in Alzheimer's disease. Neurobiology of Aging. 23: 179-86. PMID 11804701 DOI: 10.1016/S0197-4580(01)00281-0  0.352
2002 Robertson JD, Crafford AM, Markesbery WR, Lovell MA. Disruption of zinc homeostasis in Alzheimer's disease Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions With Materials and Atoms. 189: 454-458. DOI: 10.1016/S0168-583X(01)01124-7  0.398
2001 Lovell MA, Markesbery WR. Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid. Archives of Neurology. 58: 392-6. PMID 11255442 DOI: 10.1001/Archneur.58.3.392  0.398
2001 Lovell MA, Xie C, Markesbery WR. Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiology of Aging. 22: 187-94. PMID 11182468 DOI: 10.1016/S0197-4580(00)00235-9  0.411
2000 Lovell MA, Xie C, Markesbery WR. Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures. Free Radical Biology & Medicine. 29: 714-20. PMID 11053772 DOI: 10.1016/S0891-5849(00)00346-4  0.366
2000 Rulon LL, Robertson JD, Lovell MA, Deibel MA, Ehmann WD, Markesbery WR. Serum zinc levels and Alzheimer's disease Biological Trace Element Research. 75: 79-85. PMID 11051598 DOI: 10.1385/Bter:75:1-3:79  0.394
2000 Lovell MA, Xie C, Gabbita SP, Markesbery WR. Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain. Free Radical Biology & Medicine. 28: 418-27. PMID 10699754 DOI: 10.1016/S0891-5849(99)00258-0  0.418
2000 Lovell MA, Xie C, Markesbery WR. Decreased base excision repair and increased helicase activity in Alzheimer's disease brain. Brain Research. 855: 116-23. PMID 10650137 DOI: 10.1016/S0006-8993(99)02335-5  0.39
1999 Gabbita SP, Aksenov MY, Lovell MA, Markesbery WR. Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain. Journal of Neurochemistry. 73: 1660-6. PMID 10501213 DOI: 10.1046/J.1471-4159.1999.0731660.X  0.408
1999 Lovell MA, Gabbita SP, Markesbery WR. Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF. Journal of Neurochemistry. 72: 771-6. PMID 9930752 DOI: 10.1046/J.1471-4159.1999.0720771.X  0.387
1998 Lovell MA, Xie C, Markesbery WR. Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease. Neurology. 51: 1562-6. PMID 9855502 DOI: 10.1212/Wnl.51.6.1562  0.408
1998 Gabbita SP, Lovell MA, Markesbery WR. Increased nuclear DNA oxidation in the brain in Alzheimer's disease. Journal of Neurochemistry. 71: 2034-40. PMID 9798928 DOI: 10.1046/J.1471-4159.1998.71052034.X  0.416
1998 Lauterbach EC, Cummings JL, Duffy J, Coffey CE, Kaufer D, Lovell M, Malloy P, Reeve A, Royall DR, Rummans TA, Salloway SP. Neuropsychiatric correlates and treatment of lenticulostriatal diseases: a review of the literature and overview of research opportunities in Huntington's, Wilson's, and Fahr's diseases. A report of the ANPA Committee on Research. American Neuropsychiatric Association. The Journal of Neuropsychiatry and Clinical Neurosciences. 10: 249-66. PMID 9706533 DOI: 10.1176/Jnp.10.3.249  0.309
1998 Lovell MA, Robertson JD, Teesdale WJ, Campbell JL, Markesbery WR. Copper, iron and zinc in Alzheimer's disease senile plaques. Journal of the Neurological Sciences. 158: 47-52. PMID 9667777 DOI: 10.1016/S0022-510X(98)00092-6  0.347
1998 Bruce-Keller AJ, Li YJ, Lovell MA, Kraemer PJ, Gary DS, Brown RR, Markesbery WR, Mattson MP. 4-Hydroxynonenal, a product of lipid peroxidation, damages cholinergic neurons and impairs visuospatial memory in rats. Journal of Neuropathology and Experimental Neurology. 57: 257-67. PMID 9600218 DOI: 10.1097/00005072-199803000-00007  0.328
1998 Markesbery WR, Lovell MA. Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiology of Aging. 19: 33-6. PMID 9562500 DOI: 10.1016/S0197-4580(98)00009-8  0.421
1998 Prasad MR, Lovell MA, Yatin M, Dhillon H, Markesbery WR. Regional membrane phospholipid alterations in Alzheimer's disease. Neurochemical Research. 23: 81-8. PMID 9482271 DOI: 10.1023/A:1022457605436  0.366
1997 Lovell MA, Ehmann WD, Mattson MP, Markesbery WR. Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease. Neurobiology of Aging. 18: 457-61. PMID 9390770 DOI: 10.1016/S0197-4580(97)00108-5  0.415
1997 Mark RJ, Lovell MA, Markesbery WR, Uchida K, Mattson MP. A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide. Journal of Neurochemistry. 68: 255-64. PMID 8978733 DOI: 10.1046/J.1471-4159.1997.68010255.X  0.303
1995 Lovell MA, Ehmann WD, Butler SM, Markesbery WR. Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurology. 45: 1594-601. PMID 7644059 DOI: 10.1212/Wnl.45.8.1594  0.39
1995 Lovell MA, Robertson JD, Ehmann WD, Markesbery WR, Teesdale WJ, Campbell JL. Comparison of laser microprobe mass spectrometry (LMMS) and micro particle induced X-ray emission (micro-PIXE) for the analysis of senile plaques in Alzheimer's disease: A preliminary study Journal of Radioanalytical and Nuclear Chemistry Articles. 195: 7-12. DOI: 10.1007/Bf02036467  0.306
1993 Lovell MA, Ehmann WD, Markesbery WR. Laser microprobe analysis of brain aluminum in Alzheimer's disease. Annals of Neurology. 33: 36-42. PMID 8257483 DOI: 10.1002/Ana.410330107  0.352
1993 Ehmann WD, Ding X-, Khare SS, Lovell MA, Ni B-, Tandon L, Vance DE, Wenstrup DE. Activation analysis in a multitechnique study of trace element imbalances in age-related neurological diseases Journal of Radioanalytical and Nuclear Chemistry Articles. 168: 223-231. DOI: 10.1007/Bf02040894  0.304
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